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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17439722
log Bayes Factor = 11.9801
Chromosome 7   position 116,780,178  (GRCh37) Explore rs17439722 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
I20.0 Unstable angina
0.997 0.003 0.000
I20 Angina pectoris
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.994 0.006 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.990 0.010 0.000
J90-J94 Other diseases of pleura
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.985 0.015 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.984 0.016 0.000
I50 Heart failure
0.983 0.017 0.000
I47 Paroxysmal tachycardia
0.983 0.017 0.000
I26 Pulmonary embolism
0.980 0.020 0.000
I42 Cardiomyopathy
0.977 0.023 0.000
C79 Secondary malignant neoplasm of other sites
0.975 0.025 0.000
Chapter I Certain infectious and parasitic diseases
0.975 0.025 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.973 0.027 0.000
J95-J99 Other diseases of the respiratory system
0.970 0.030 0.000
Chapter VI Diseases of the nervous system
0.967 0.033 0.000
C15-C26 Malignant neoplasms of digestive organs
0.967 0.033 0.000
J92 Pleural plaque
0.958 0.042 0.000
I50.0 Congestive heart failure
0.958 0.042 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.957 0.043 0.000
H30-H36 Disorders of choroid and retina
0.955 0.045 0.000
E10-E14 Diabetes mellitus
0.955 0.045 0.000
E70-E90 Metabolic disorders
0.947 0.053 0.000
I47.1 Supraventricular tachycardia
0.939 0.061 0.000
J90 Pleural effusion, not elsewhere classified
0.938 0.062 0.000
A30-A49 Other bacterial diseases
0.935 0.065 0.000
H40-H42 Glaucoma
0.934 0.066 0.000
I24 Other acute ischaemic heart diseases
0.927 0.073 0.000
J98 Other respiratory disorders
0.926 0.074 0.000
I05-I09 Chronic rheumatic heart diseases
0.925 0.075 0.000
C78.0 Secondary malignant neoplasm of lung
0.919 0.081 0.000
E11 Non-insulin-dependent diabetes mellitus
0.913 0.087 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.908 0.092 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.900 0.100 0.000
I42.9 Cardiomyopathy, unspecified
0.900 0.100 0.000
Chapter V Mental and behavioural disorders
0.899 0.101 0.000
A41 Other septicaemia
0.899 0.101 0.000
E10 Insulin-dependent diabetes mellitus
0.898 0.102 0.000
I49 Other cardiac arrhythmias
0.898 0.102 0.000
J92.0 Pleural plaque with presence of asbestos
0.895 0.105 0.000
B95-B98 Bacterial, viral and other infectious agents
0.894 0.106 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.893 0.107 0.000
I47.2 Ventricular tachycardia
0.892 0.108 0.000
J98.1 Pulmonary collapse
0.891 0.109 0.000
H40 Glaucoma
0.891 0.109 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.889 0.111 0.000
C78.7 Secondary malignant neoplasm of liver
0.885 0.115 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.883 0.117 0.000
H10-H13 Disorders of conjunctiva
0.882 0.118 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.881 0.119 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.880 0.120 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.872 0.128 0.000
J92.9 Pleural plaque without asbestos
0.871 0.129 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.869 0.131 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.866 0.134 0.000
H36 Retinal disorders in diseases classified elsewhere
0.863 0.137 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.862 0.138 0.000
I50.1 Left ventricular failure
0.862 0.138 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.861 0.139 0.000
C17 Malignant neoplasm of small intestine
0.860 0.140 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.857 0.142 0.000
A41.9 Septicaemia, unspecified
0.857 0.143 0.000
E11.3 With ophthalmic complications
0.855 0.145 0.000
I08 Multiple valve diseases
0.853 0.147 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.846 0.154 0.000
H40.1 Primary open-angle glaucoma
0.844 0.156 0.000
J09-J18 Influenza and pneumonia
0.842 0.158 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.842 0.158 0.000
J60-J70 Lung diseases due to external agents
0.842 0.158 0.000
E87.5 Hyperkalaemia
0.840 0.160 0.000
H40.9 Glaucoma, unspecified
0.839 0.161 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.838 0.162 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.836 0.164 0.000
D68 Other coagulation defects
0.832 0.168 0.000
Chapter XX External causes of morbidity and mortality
0.831 0.169 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.830 0.170 0.000
I60-I69 Cerebrovascular diseases
0.827 0.173 0.000
I36 Nonrheumatic tricuspid valve disorders
0.827 0.173 0.000
I21 Acute myocardial infarction
0.824 0.176 0.000
E11.4 With neurological complications
0.824 0.176 0.000
G35 Multiple sclerosis
0.822 0.178 0.000
H11 Other disorders of conjunctiva
0.821 0.179 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.819 0.181 0.000
I24.8 Other forms of acute ischaemic heart disease
0.818 0.182 0.000
G90-G99 Other disorders of the nervous system
0.818 0.182 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.818 0.182 0.000
G70-G73 Diseases of myoneural junction and muscle
0.816 0.184 0.000
C80 Malignant neoplasm without specification of site
0.815 0.185 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.813 0.187 0.000
I49.1 Atrial premature depolarisation
0.811 0.189 0.000
I42.6 Alcoholic cardiomyopathy
0.809 0.191 0.000
E74 Other disorders of carbohydrate metabolism
0.807 0.193 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.804 0.196 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.802 0.198 0.000
I27 Other pulmonary heart diseases
0.799 0.201 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.799 0.201 0.000
H36.0 Diabetic retinopathy
0.798 0.202 0.000
I25 Chronic ischaemic heart disease
0.797 0.203 0.000
I22 Subsequent myocardial infarction
0.797 0.203 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.797 0.203 0.000
I21.9 Acute myocardial infarction, unspecified
0.796 0.204 0.000
I42.0 Dilated cardiomyopathy
0.795 0.205 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.795 0.205 0.000
H35 Other retinal disorders
0.792 0.208 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.792 0.208 0.000
H25-H28 Disorders of lens
0.791 0.209 0.000
E10.1 With ketoacidosis
0.790 0.210 0.000
C83.3 Large cell (diffuse)
0.789 0.211 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.788 0.212 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.786 0.214 0.000
B35-B49 Mycoses
0.784 0.216 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.784 0.216 0.000
C71 Malignant neoplasm of brain
0.780 0.220 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.776 0.224 0.000
I45 Other conduction disorders
0.774 0.226 0.000
E20-E35 Disorders of other endocrine glands
0.772 0.228 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.772 0.228 0.000
I33 Acute and subacute endocarditis
0.769 0.231 0.000
C16 Malignant neoplasm of stomach
0.766 0.234 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.766 0.234 0.000
D68.2 Hereditary deficiency of other clotting factors
0.765 0.235 0.000
F43 Reaction to severe stress, and adjustment disorders
0.764 0.236 0.000
E89.0 Postprocedural hypothyroidism
0.764 0.236 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.763 0.237 0.000
H34 Retinal vascular occlusions
0.763 0.237 0.000
H33 Retinal detachments and breaks
0.760 0.240 0.000
J18 Pneumonia, organism unspecified
0.758 0.242 0.000
F40 Phobic anxiety disorders
0.758 0.242 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.756 0.244 0.000
Chapter XXII Codes for special purposes
0.754 0.246 0.000
H55-H59 Other disorders of eye and adnexa
0.754 0.246 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.754 0.246 0.000
I37 Pulmonary valve disorders
0.751 0.249 0.000
I35 Nonrheumatic aortic valve disorders
0.751 0.249 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.750 0.250 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.748 0.252 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.748 0.252 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.748 0.252 0.000
B91 Sequelae of poliomyelitis
0.747 0.253 0.000
I42.2 Other hypertrophic cardiomyopathy
0.747 0.253 0.000
C23 Malignant neoplasm of gallbladder
0.745 0.255 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.744 0.256 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.743 0.256 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.741 0.259 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.740 0.260 0.000
C88 Malignant immunoproliferative diseases
0.740 0.260 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.738 0.262 0.000
E10.3 With ophthalmic complications
0.737 0.263 0.000
D37.4 Colon
0.737 0.263 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.736 0.264 0.000
C17.0 Duodenum
0.735 0.265 0.000
E11.6 With other specified complications
0.734 0.266 0.000
E10.6 With other specified complications
0.733 0.267 0.000
I49.0 Ventricular fibrillation and flutter
0.733 0.267 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.733 0.267 0.000
C15 Malignant neoplasm of oesophagus
0.732 0.268 0.000
C21 Malignant neoplasm of anus and anal canal
0.732 0.268 0.000
C81 Hodgkin's disease
0.729 0.270 0.000
I07 Rheumatic tricuspid valve diseases
0.729 0.271 0.000
C78.2 Secondary malignant neoplasm of pleura
0.728 0.272 0.000
E83 Disorders of mineral metabolism
0.726 0.273 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.726 0.274 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.724 0.276 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.724 0.276 0.000
A49 Bacterial infection of unspecified site
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I30 Acute pericarditis
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.716 0.284 0.000
G30-G32 Other degenerative diseases of the nervous system
0.714 0.286 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.714 0.286 0.000
J18.1 Lobar pneumonia, unspecified
0.714 0.286 0.000
C17.9 Small intestine, unspecified
0.712 0.288 0.000
E73 Lactose intolerance
0.710 0.289 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.711 0.289 0.000
E11.2 With renal complications
0.710 0.289 0.000
I28 Other diseases of pulmonary vessels
0.710 0.290 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.709 0.291 0.000
C77.1 Intrathoracic lymph nodes
0.709 0.291 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.708 0.292 0.000
J94 Other pleural conditions
0.707 0.292 0.000
J69 Pneumonitis due to solids and liquids
0.707 0.292 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.706 0.294 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.706 0.294 0.000
I45.6 Preexcitation syndrome
0.706 0.294 0.000
I44 Atrioventricular and left bundle-branch block
0.705 0.295 0.000
D68.8 Other specified coagulation defects
0.705 0.295 0.000
I47.0 Reentry ventricular arrhythmia
0.705 0.295 0.000
H33.5 Other retinal detachments
0.705 0.295 0.000
A41.8 Other specified septicaemia
0.704 0.296 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.703 0.297 0.000
C20 Malignant neoplasm of rectum
0.703 0.297 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.703 0.297 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.703 0.297 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.701 0.299 0.000
I42.8 Other cardiomyopathies
0.700 0.300 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.700 0.300 0.000
I42.5 Other restrictive cardiomyopathy
0.700 0.300 0.000
I42.4 Endocardial fibroelastosis
0.700 0.300 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.700 0.300 0.000
I62 Other nontraumatic intracranial haemorrhage
0.700 0.300 0.000
C79.6 Secondary malignant neoplasm of ovary
0.699 0.301 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.699 0.301 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.699 0.301 0.000
B99-B99 Other infectious diseases
0.699 0.301 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.699 0.301 0.000
B50-B64 Protozoal diseases
0.699 0.301 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.699 0.301 0.000
A80-A89 Viral infections of the central nervous system
0.699 0.301 0.000
A75-A79 Rickettsioses
0.699 0.301 0.000
A70-A74 Other diseases caused by chlamydiae
0.699 0.301 0.000
A65-A69 Other spirochaetal diseases
0.699 0.301 0.000
A20-A28 Certain zoonotic bacterial diseases
0.699 0.301 0.000
A15-A19 Tuberculosis
0.699 0.301 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.697 0.303 0.000
H43-H45 Disorders of vitreous body and globe
0.696 0.304 0.000
J96 Respiratory failure, not elsewhere classified
0.695 0.305 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.695 0.305 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.695 0.305 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.693 0.307 0.000
I61 Intracerebral haemorrhage
0.692 0.308 0.000
E10.4 With neurological complications
0.692 0.308 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.692 0.308 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.692 0.308 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.691 0.309 0.000
F41 Other anxiety disorders
0.691 0.309 0.000
T66-T78 Other and unspecified effects of external causes
0.690 0.310 0.000
E40-E46 Malnutrition
0.690 0.310 0.000
F43.2 Adjustment disorders
0.690 0.310 0.000
D66 Hereditary factor VIII deficiency
0.687 0.313 0.000
C92 Myeloid leukaemia
0.687 0.313 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.686 0.313 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.686 0.314 0.000
C95 Leukaemia of unspecified cell type
0.686 0.314 0.000
C94 Other leukaemias of specified cell type
0.686 0.314 0.000
C93 Monocytic leukaemia
0.686 0.314 0.000
C86 Other specified types of T/NK-cell lymphoma
0.686 0.314 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.686 0.314 0.000
E11.5 With peripheral circulatory complications
0.686 0.314 0.000
F45 Somatoform disorders
0.685 0.315 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.685 0.315 0.000
H31 Other disorders of choroid
0.685 0.315 0.000
H30 Chorioretinal inflammation
0.685 0.315 0.000
E12 Malnutrition-related diabetes mellitus
0.684 0.315 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.683 0.317 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.683 0.317 0.000
E83.5 Disorders of calcium metabolism
0.683 0.317 0.000
C25 Malignant neoplasm of pancreas
0.682 0.317 0.000
G57 Mononeuropathies of lower limb
0.682 0.318 0.000
C71.9 Brain, unspecified
0.682 0.318 0.000
F60-F69 Disorders of adult personality and behaviour
0.682 0.318 0.000
J98.9 Respiratory disorder, unspecified
0.681 0.319 0.000
B44 Aspergillosis
0.680 0.320 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.680 0.320 0.000
S20-S29 Injuries to the thorax
0.679 0.321 0.000
E85 Amyloidosis
0.679 0.321 0.000
E84 Cystic fibrosis
0.679 0.321 0.000
E79 Disorders of purine and pyrimidine metabolism
0.679 0.321 0.000
E77 Disorders of glycoprotein metabolism
0.679 0.321 0.000
E76 Disorders of glycosaminoglycan metabolism
0.679 0.321 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.679 0.321 0.000
E72 Other disorders of amino-acid metabolism
0.679 0.321 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.679 0.321 0.000
E70 Disorders of aromatic amino-acid metabolism
0.679 0.321 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.679 0.321 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.678 0.322 0.000
E00-E07 Disorders of thyroid gland
0.678 0.322 0.000
C85.1 B-cell lymphoma, unspecified
0.677 0.323 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.675 0.325 0.000
I50.9 Heart failure, unspecified
0.674 0.326 0.000
I49.4 Other and unspecified premature depolarisation
0.672 0.328 0.000
Y52 Agents primarily affecting the cardiovascular system
0.671 0.329 0.000
C91 Lymphoid leukaemia
0.671 0.329 0.000
G54 Nerve root and plexus disorders
0.671 0.329 0.000
J91 Pleural effusion in conditions classified elsewhere
0.670 0.329 0.000
G51 Facial nerve disorders
0.670 0.330 0.000
A48 Other bacterial diseases, not elsewhere classified
0.670 0.330 0.000
A44 Bartonellosis
0.670 0.330 0.000
A43 Nocardiosis
0.670 0.330 0.000
A42 Actinomycosis
0.670 0.330 0.000
A40 Streptococcal septicaemia
0.670 0.330 0.000
A39 Meningococcal infection
0.670 0.330 0.000
A37 Whooping cough
0.670 0.330 0.000
A36 Diphtheria
0.670 0.330 0.000
A32 Listeriosis
0.670 0.330 0.000
A31 Infection due to other mycobacteria
0.670 0.330 0.000
A30 Leprosy [Hansen's disease]
0.670 0.330 0.000
A46 Erysipelas
0.670 0.330 0.000
A38 Scarlet fever
0.670 0.330 0.000
A35 Other tetanus
0.670 0.330 0.000
A34 Obstetrical tetanus
0.670 0.330 0.000
A33 Tetanus neonatorum
0.670 0.330 0.000
H42 Glaucoma in diseases classified elsewhere
0.670 0.330 0.000
E86 Volume depletion
0.668 0.332 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.668 0.332 0.000
I49.5 Sick sinus syndrome
0.667 0.333 0.000
Q00-Q07 Congenital malformations of the nervous system
0.666 0.334 0.000
Q80-Q89 Other congenital malformations
0.665 0.334 0.000
G70 Myasthenia gravis and other myoneural disorders
0.665 0.335 0.000
I24.1 Dressler's syndrome
0.664 0.336 0.000
X60-X84 Intentional self-harm
0.664 0.336 0.000
J98.6 Disorders of diaphragm
0.664 0.336 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.664 0.336 0.000
J98.3 Compensatory emphysema
0.664 0.336 0.000
J98.2 Interstitial emphysema
0.664 0.336 0.000
I09 Other rheumatic heart diseases
0.663 0.337 0.000
I06 Rheumatic aortic valve diseases
0.663 0.337 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.663 0.337 0.000
I60 Subarachnoid haemorrhage
0.662 0.338 0.000
E87.7 Fluid overload
0.660 0.339 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.660 0.340 0.000
G20-G26 Extrapyramidal and movement disorders
0.660 0.340 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.660 0.340 0.000
I05 Rheumatic mitral valve diseases
0.660 0.340 0.000
E10.5 With peripheral circulatory complications
0.660 0.340 0.000
I35.9 Aortic valve disorder, unspecified
0.659 0.341 0.000
G93 Other disorders of brain
0.659 0.341 0.000
H35.3 Degeneration of macula and posterior pole
0.658 0.342 0.000
Q23 Congenital malformations of aortic and mitral valves
0.657 0.343 0.000
E11.1 With ketoacidosis
0.657 0.343 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.656 0.344 0.000
I49.8 Other specified cardiac arrhythmias
0.656 0.344 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.656 0.344 0.000
F42 Obsessive-compulsive disorder
0.656 0.344 0.000
H11.0 Pterygium
0.656 0.344 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.655 0.345 0.000
E11.8 With unspecified complications
0.654 0.345 0.000
E11.7 With multiple complications
0.654 0.345 0.000
E11.0 With coma
0.654 0.345 0.000
G40-G47 Episodic and paroxysmal disorders
0.654 0.345 0.000
J93 Pneumothorax
0.654 0.346 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.654 0.346 0.000
F80-F89 Disorders of psychological development
0.653 0.347 0.000
E88 Other metabolic disorders
0.652 0.348 0.000
B25-B34 Other viral diseases
0.651 0.349 0.000
E87.4 Mixed disorder of acid-base balance
0.651 0.349 0.000
E87.3 Alkalosis
0.651 0.349 0.000
G71 Primary disorders of muscles
0.651 0.349 0.000
H11.8 Other specified disorders of conjunctiva
0.650 0.350 0.000
E87.6 Hypokalaemia
0.650 0.350 0.000
D68.6 Other Thrombophilia
0.649 0.351 0.000
D50-D53 Nutritional anaemias
0.648 0.352 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.648 0.352 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.648 0.352 0.000
H11.1 Conjunctival degenerations and deposits
0.647 0.353 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.647 0.353 0.000
S70-S79 Injuries to the hip and thigh
0.646 0.354 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.646 0.354 0.000
E87.0 Hyperosmolality and hypernatraemia
0.646 0.354 0.000
D55-D59 Haemolytic anaemias
0.646 0.354 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.645 0.355 0.000
F70-F79 Mental retardation
0.645 0.355 0.000
A41.4 Septicaemia due to anaerobes
0.645 0.355 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.645 0.355 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.645 0.355 0.000
F40.2 Specific (isolated) phobias
0.644 0.356 0.000
E10.8 With unspecified complications
0.644 0.356 0.000
E10.7 With multiple complications
0.644 0.356 0.000
E10.2 With renal complications
0.644 0.356 0.000
E10.0 With coma
0.644 0.356 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.644 0.356 0.000
I49.2 Junctional premature depolarisation
0.643 0.356 0.000
Y57 Other and unspecified drugs and medicaments
0.643 0.357 0.000
J80 Adult respiratory distress syndrome
0.643 0.357 0.000
D80-D89 Certain disorders involving the immune mechanism
0.642 0.358 0.000
C77.5 Intrapelvic lymph nodes
0.642 0.358 0.000
I25.3 Aneurysm of heart
0.641 0.359 0.000
S50-S59 Injuries to the elbow and forearm
0.641 0.359 0.000
G95 Other diseases of spinal cord
0.641 0.359 0.000
G90 Disorders of autonomic nervous system
0.640 0.360 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.640 0.360 0.000
I46 Cardiac arrest
0.640 0.360 0.000
E13 Other specified diabetes mellitus
0.639 0.360 0.000
H40.8 Other glaucoma
0.639 0.361 0.000
H40.6 Glaucoma secondary to drugs
0.639 0.361 0.000
H40.4 Glaucoma secondary to eye inflammation
0.639 0.361 0.000
H40.3 Glaucoma secondary to eye trauma
0.639 0.361 0.000
I20.8 Other forms of angina pectoris
0.638 0.362 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.638 0.362 0.000
Q35-Q37 Cleft lip and cleft palate
0.638 0.362 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.638 0.362 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.638 0.362 0.000
F99-F99 Unspecified mental disorder
0.637 0.363 0.000
I67 Other cerebrovascular diseases
0.637 0.363 0.000
J00-J06 Acute upper respiratory infections
0.636 0.364 0.000
E89.2 Postprocedural hypoparathyroidism
0.636 0.364 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.635 0.365 0.000
B15-B19 Viral hepatitis
0.635 0.365 0.000
C51-C58 Malignant neoplasms of female genital organs
0.634 0.366 0.000
E27 Other disorders of adrenal gland
0.633 0.366 0.000
I27.0 Primary pulmonary hypertension
0.633 0.367 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.633 0.367 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.633 0.367 0.000
C85.0 Lymphosarcoma
0.633 0.367 0.000
J11 Influenza, virus not identified
0.633 0.367 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.633 0.367 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.632 0.368 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.632 0.368 0.000
G36 Other acute disseminated demyelination
0.631 0.369 0.000
G47 Sleep disorders
0.631 0.369 0.000
H34.8 Other retinal vascular occlusions
0.630 0.370 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.629 0.370 0.000
H57 Other disorders of eye and adnexa
0.630 0.370 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.629 0.371 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.629 0.371 0.000
Q50-Q56 Congenital malformations of genital organs
0.629 0.371 0.000
H40.5 Glaucoma secondary to other eye disorders
0.628 0.372 0.000
H35.0 Background retinopathy and retinal vascular changes
0.627 0.372 0.000
I27.8 Other specified pulmonary heart diseases
0.627 0.373 0.000
Y00-Y09 Assault
0.626 0.374 0.000
B35 Dermatophytosis
0.625 0.375 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.625 0.375 0.000
C70 Malignant neoplasm of meninges
0.625 0.375 0.000
C69 Malignant neoplasm of eye and adnexa
0.625 0.375 0.000
F20 Schizophrenia
0.624 0.376 0.000
A49.0 Staphylococcal infection, unspecified
0.624 0.376 0.000
F48 Other neurotic disorders
0.623 0.377 0.000
F44 Dissociative [conversion] disorders
0.623 0.377 0.000
Y42.7 Androgens and anabolic congeners
0.622 0.378 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.622 0.378 0.000
I49.3 Ventricular premature depolarisation
0.622 0.378 0.000
D68.5 Primary Thrombophilia
0.622 0.378 0.000
D68.9 Coagulation defect, unspecified
0.621 0.379 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.621 0.379 0.000
H50 Other strabismus
0.621 0.379 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.620 0.380 0.000
J84 Other interstitial pulmonary diseases
0.620 0.380 0.000
I69 Sequelae of cerebrovascular disease
0.619 0.381 0.000
C60-C63 Malignant neoplasms of male genital organs
0.619 0.381 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.619 0.381 0.000
J98.8 Other specified respiratory disorders
0.619 0.381 0.000
C77.8 Lymph nodes of multiple regions
0.618 0.381 0.000
D67 Hereditary factor IX deficiency
0.618 0.382 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.618 0.382 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.618 0.382 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.618 0.382 0.000
T78 Adverse effects, not elsewhere classified
0.618 0.382 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.618 0.382 0.000
C83.7 Burkitt's tumour
0.618 0.382 0.000
C83.6 Undifferentiated (diffuse)
0.618 0.382 0.000
C83.5 Lymphoblastic (diffuse)
0.618 0.382 0.000
C83.4 Immunoblastic (diffuse)
0.618 0.382 0.000
C83.2 Mixed small and large cell (diffuse)
0.618 0.382 0.000
C83.1 Small cleaved cell (diffuse)
0.618 0.382 0.000
C83.0 Small cell (diffuse)
0.618 0.382 0.000
G37 Other demyelinating diseases of central nervous system
0.617 0.383 0.000
C17.8 Overlapping lesion of small intestine
0.617 0.383 0.000
C17.3 Meckel's diverticulum
0.617 0.383 0.000
C17.2 Ileum
0.617 0.383 0.000
C17.1 Jejunum
0.617 0.383 0.000
H53-H54 Visual disturbances and blindness
0.617 0.383 0.000
H40.2 Primary angle-closure glaucoma
0.617 0.383 0.000
G47.3 Sleep apnoea
0.616 0.384 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.616 0.384 0.000
H35.9 Retinal disorder, unspecified
0.616 0.384 0.000
I44.7 Left bundle-branch block, unspecified
0.616 0.384 0.000
H49 Paralytic strabismus
0.615 0.384 0.000
C16.0 Cardia
0.615 0.385 0.000
C18 Malignant neoplasm of colon
0.614 0.386 0.000
F41.9 Anxiety disorder, unspecified
0.612 0.388 0.000
I08.9 Multiple valve disease, unspecified
0.612 0.388 0.000
I08.8 Other multiple valve diseases
0.612 0.388 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.612 0.388 0.000
H25 Senile cataract
0.611 0.389 0.000
J69.0 Pneumonitis due to food and vomit
0.611 0.389 0.000
E87.2 Acidosis
0.610 0.390 0.000
S90-S99 Injuries to the ankle and foot
0.610 0.390 0.000
H26 Other cataract
0.610 0.390 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.609 0.391 0.000
I08.0 Disorders of both mitral and aortic valves
0.608 0.392 0.000
F40.0 Agoraphobia
0.608 0.392 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.607 0.393 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.607 0.393 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.607 0.393 0.000
E89.5 Postprocedural testicular hypofunction
0.607 0.393 0.000
E89.4 Postprocedural ovarian failure
0.607 0.393 0.000
E89.3 Postprocedural hypopituitarism
0.607 0.393 0.000
E89.1 Postprocedural hypoinsulinaemia
0.607 0.393 0.000
G91 Hydrocephalus
0.606 0.394 0.000
V80-V89 Other land transport accidents
0.606 0.394 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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