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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17561091
log Bayes Factor = 19.659
Chromosome 18   position 33,053,097  (GRCh37) Explore rs17561091 on Ensembl!
Variant rs17561091 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
F30-F39 Mood [affective] disorders
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
E11 Non-insulin-dependent diabetes mellitus
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.989 0.011 0.000
I20-I25 Ischaemic heart diseases
0.987 0.013 0.000
E11.9 Without complications
0.987 0.013 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.985 0.015 0.000
Chapter X Diseases of the respiratory system
0.979 0.021 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.976 0.024 0.000
W00-W19 Falls
0.973 0.027 0.000
E70-E90 Metabolic disorders
0.972 0.028 0.000
M20-M25 Other joint disorders
0.967 0.033 0.000
I69 Sequelae of cerebrovascular disease
0.964 0.036 0.000
F31 Bipolar affective disorder
0.963 0.037 0.000
J20-J22 Other acute lower respiratory infections
0.960 0.040 0.000
S70-S79 Injuries to the hip and thigh
0.959 0.041 0.000
F32 Depressive episode
0.958 0.042 0.000
E83 Disorders of mineral metabolism
0.958 0.042 0.000
I25 Chronic ischaemic heart disease
0.956 0.044 0.000
G40-G47 Episodic and paroxysmal disorders
0.955 0.045 0.000
G90-G99 Other disorders of the nervous system
0.954 0.046 0.000
F33 Recurrent depressive disorder
0.953 0.047 0.000
M25 Other joint disorders, not elsewhere classified
0.950 0.050 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.950 0.050 0.000
Q60-Q64 Congenital malformations of the urinary system
0.950 0.050 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.949 0.051 0.000
Chapter I Certain infectious and parasitic diseases
0.946 0.054 0.000
N00-N08 Glomerular diseases
0.945 0.055 0.000
J22 Unspecified acute lower respiratory infection
0.942 0.058 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.940 0.060 0.000
E10 Insulin-dependent diabetes mellitus
0.939 0.061 0.000
J09-J18 Influenza and pneumonia
0.938 0.062 0.000
N10-N16 Renal tubulo-interstitial diseases
0.938 0.062 0.000
I63 Cerebral infarction
0.937 0.063 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.935 0.065 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.933 0.067 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.926 0.074 0.000
E83.5 Disorders of calcium metabolism
0.925 0.075 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.925 0.075 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.921 0.079 0.000
M40-M43 Deforming dorsopathies
0.921 0.079 0.000
N99-N99 Other disorders of the genitourinary system
0.921 0.079 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.914 0.086 0.000
F33.9 Recurrent depressive disorder, unspecified
0.909 0.091 0.000
M80-M85 Disorders of bone density and structure
0.907 0.093 0.000
N02 Recurrent and persistent haematuria
0.906 0.094 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.906 0.094 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.903 0.097 0.000
Q61 Cystic kidney disease
0.902 0.098 0.000
G81 Hemiplegia
0.901 0.099 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.898 0.102 0.000
G20-G26 Extrapyramidal and movement disorders
0.893 0.107 0.000
N25-N29 Other disorders of kidney and ureter
0.893 0.107 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.892 0.108 0.000
V80-V89 Other land transport accidents
0.892 0.108 0.000
S72 Fracture of femur
0.891 0.109 0.000
G30-G32 Other degenerative diseases of the nervous system
0.891 0.109 0.000
W19 Unspecified fall
0.887 0.113 0.000
E83.4 Disorders of magnesium metabolism
0.885 0.115 0.000
F32.9 Depressive episode, unspecified
0.884 0.116 0.000
I63.9 Cerebral infarction, unspecified
0.884 0.116 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.884 0.116 0.000
E86 Volume depletion
0.881 0.119 0.000
E10.9 Without complications
0.878 0.122 0.000
E14 Unspecified diabetes mellitus
0.877 0.122 0.000
G81.9 Hemiplegia, unspecified
0.877 0.123 0.000
I67 Other cerebrovascular diseases
0.877 0.123 0.000
M24 Other specific joint derangements
0.876 0.124 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.876 0.124 0.000
N02.9 Unspecified
0.875 0.125 0.000
T39.1 4-Aminophenol derivatives
0.874 0.126 0.000
S90-S99 Injuries to the ankle and foot
0.871 0.129 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.867 0.133 0.000
E20-E35 Disorders of other endocrine glands
0.864 0.136 0.000
W07 Fall involving chair
0.863 0.137 0.000
W20-W49 Exposure to inanimate mechanical forces
0.862 0.138 0.000
N72 Inflammatory disease of cervix uteri
0.860 0.140 0.000
S72.0 Fracture of neck of femur
0.860 0.140 0.000
J18 Pneumonia, organism unspecified
0.860 0.140 0.000
I22 Subsequent myocardial infarction
0.859 0.141 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.855 0.145 0.000
I21 Acute myocardial infarction
0.855 0.145 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.854 0.146 0.000
M25.5 Pain in joint
0.854 0.146 0.000
Q61.3 Polycystic kidney, unspecified
0.853 0.147 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.853 0.147 0.000
M25.8 Other specified joint disorders
0.846 0.154 0.000
M21 Other acquired deformities of limbs
0.844 0.156 0.000
N75 Diseases of Bartholin's gland
0.843 0.157 0.000
M41 Scoliosis
0.842 0.158 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.841 0.159 0.000
S72.00 Fracture of neck of femur (closed)
0.838 0.162 0.000
M31 Other necrotising vasculopathies
0.835 0.165 0.000
I69.3 Sequelae of cerebral infarction
0.835 0.165 0.000
E14.9 Without complications
0.834 0.166 0.000
G45.3 Amaurosis fugax
0.834 0.166 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.832 0.168 0.000
D50-D53 Nutritional anaemias
0.832 0.168 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.830 0.170 0.000
T79-T79 Certain early complications of trauma
0.828 0.172 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.826 0.174 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.824 0.176 0.000
Chapter XXII Codes for special purposes
0.823 0.177 0.000
V40-V49 Car occupant injured in transport accident
0.821 0.179 0.000
E11.4 With neurological complications
0.821 0.179 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.820 0.180 0.000
R25 Abnormal involuntary movements
0.820 0.180 0.000
I78 Diseases of capillaries
0.820 0.180 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.819 0.181 0.000
N20-N23 Urolithiasis
0.819 0.181 0.000
B02 Zoster [herpes zoster]
0.819 0.181 0.000
G20 Parkinson's disease
0.817 0.183 0.000
E10.4 With neurological complications
0.816 0.184 0.000
D50.8 Other iron deficiency anaemias
0.815 0.185 0.000
D50 Iron deficiency anaemia
0.815 0.185 0.000
M86-M90 Other osteopathies
0.815 0.185 0.000
G03 Meningitis due to other and unspecified causes
0.813 0.187 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.813 0.187 0.000
V20-V29 Motorcycle rider injured in transport accident
0.813 0.187 0.000
T43.2 Other and unspecified antidepressants
0.811 0.189 0.000
I24 Other acute ischaemic heart diseases
0.811 0.189 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.811 0.189 0.000
F31.9 Bipolar affective disorder, unspecified
0.810 0.190 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.809 0.191 0.000
B07 Viral warts
0.808 0.192 0.000
I05-I09 Chronic rheumatic heart diseases
0.808 0.192 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.806 0.194 0.000
E40-E46 Malnutrition
0.804 0.196 0.000
M80 Osteoporosis with pathological fracture
0.803 0.196 0.000
A80-A89 Viral infections of the central nervous system
0.802 0.198 0.000
J40-J47 Chronic lower respiratory diseases
0.800 0.200 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.800 0.200 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.800 0.200 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.799 0.201 0.000
Q63 Other congenital malformations of kidney
0.798 0.202 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.798 0.202 0.000
I78.1 Naevus, nonneoplastic
0.797 0.203 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.796 0.204 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.795 0.205 0.000
E83.3 Disorders of phosphorus metabolism
0.794 0.206 0.000
I10-I15 Hypertensive diseases
0.792 0.208 0.000
M25.9 Joint disorder, unspecified
0.790 0.210 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.790 0.210 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.790 0.210 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.788 0.212 0.000
W10 Fall on and from stairs and steps
0.787 0.213 0.000
Q00-Q07 Congenital malformations of the nervous system
0.787 0.213 0.000
N30-N39 Other diseases of urinary system
0.786 0.214 0.000
M41.9 Scoliosis, unspecified
0.786 0.214 0.000
S80-S89 Injuries to the knee and lower leg
0.785 0.215 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.785 0.215 0.000
G96 Other disorders of central nervous system
0.784 0.216 0.000
W19.4 Street and highway
0.784 0.216 0.000
M25.7 Osteophyte
0.783 0.217 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.783 0.217 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.783 0.217 0.000
A30-A49 Other bacterial diseases
0.782 0.218 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.780 0.220 0.000
F03 Unspecified dementia
0.780 0.220 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.779 0.221 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.779 0.221 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.779 0.221 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.779 0.221 0.000
W07.0 Home
0.776 0.223 0.000
R25.1 Tremor, unspecified
0.776 0.224 0.000
N10 Acute tubulo-interstitial nephritis
0.776 0.224 0.000
M60-M63 Disorders of muscles
0.775 0.225 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.773 0.227 0.000
M84 Disorders of continuity of bone
0.773 0.227 0.000
G45.4 Transient global amnesia
0.772 0.228 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.772 0.228 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.772 0.228 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.772 0.228 0.000
I62 Other nontraumatic intracranial haemorrhage
0.771 0.229 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.770 0.229 0.000
T93 Sequelae of injuries of lower limb
0.770 0.230 0.000
F99-F99 Unspecified mental disorder
0.770 0.230 0.000
M45-M49 Spondylopathies
0.769 0.231 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.767 0.233 0.000
E11.6 With other specified complications
0.764 0.235 0.000
M25.56 Pain in joint (Lower leg)
0.764 0.236 0.000
J20 Acute bronchitis
0.764 0.236 0.000
N75.1 Abscess of Bartholin's gland
0.764 0.236 0.000
E23 Hypofunction and other disorders of pituitary gland
0.764 0.236 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.764 0.236 0.000
F80-F89 Disorders of psychological development
0.761 0.239 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.761 0.239 0.000
N11 Chronic tubulo-interstitial nephritis
0.760 0.240 0.000
S71 Open wound of hip and thigh
0.760 0.240 0.000
G95 Other diseases of spinal cord
0.759 0.240 0.000
M43 Other deforming dorsopathies
0.759 0.241 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.758 0.242 0.000
N70 Salpingitis and oophoritis
0.758 0.242 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.758 0.242 0.000
J18.1 Lobar pneumonia, unspecified
0.758 0.242 0.000
R47-R49 Symptoms and signs involving speech and voice
0.757 0.243 0.000
W50-W64 Exposure to animate mechanical forces
0.756 0.243 0.000
R29.6 Tendency to fall, not elsewhere classified
0.756 0.244 0.000
R26 Abnormalities of gait and mobility
0.756 0.244 0.000
Y00-Y09 Assault
0.755 0.245 0.000
J40 Bronchitis, not specified as acute or chronic
0.754 0.246 0.000
M25.3 Other instability of joint
0.753 0.247 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.752 0.248 0.000
F30 Manic episode
0.752 0.248 0.000
N76 Other inflammation of vagina and vulva
0.751 0.249 0.000
T92 Sequelae of injuries of upper limb
0.751 0.249 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.749 0.251 0.000
G91 Hydrocephalus
0.749 0.251 0.000
S10-S19 Injuries to the neck
0.748 0.252 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.747 0.253 0.000
I71 Aortic aneurysm and dissection
0.747 0.253 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.747 0.253 0.000
Q50-Q56 Congenital malformations of genital organs
0.746 0.253 0.000
Q80-Q89 Other congenital malformations
0.746 0.254 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.746 0.254 0.000
N35 Urethral stricture
0.745 0.255 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.744 0.256 0.000
N20 Calculus of kidney and ureter
0.743 0.257 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.743 0.257 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.741 0.259 0.000
W18 Other fall on same level
0.740 0.260 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.740 0.260 0.000
N03 Chronic nephritic syndrome
0.739 0.261 0.000
M31.6 Other giant cell arteritis
0.738 0.262 0.000
N13 Obstructive and reflux uropathy
0.738 0.262 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.737 0.262 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.737 0.263 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.737 0.263 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.737 0.263 0.000
G90 Disorders of autonomic nervous system
0.736 0.263 0.000
Q61.2 Polycystic kidney, adult type
0.735 0.265 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.735 0.265 0.000
E74 Other disorders of carbohydrate metabolism
0.735 0.265 0.000
N36 Other disorders of urethra
0.734 0.266 0.000
E65-E68 Obesity and other hyperalimentation
0.733 0.267 0.000
M00-M03 Infectious arthropathies
0.732 0.268 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.731 0.269 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.731 0.269 0.000
M30 Polyarteritis nodosa and related conditions
0.731 0.269 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.731 0.269 0.000
I67.8 Other specified cerebrovascular diseases
0.731 0.269 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.730 0.269 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.730 0.270 0.000
S00-S09 Injuries to the head
0.730 0.270 0.000
X20-X29 Contact with venomous animals and plants
0.728 0.272 0.000
J18.9 Pneumonia, unspecified
0.728 0.272 0.000
Y40 Systemic antibiotics
0.728 0.272 0.000
S79 Other and unspecified injuries of hip and thigh
0.726 0.274 0.000
W06 Fall involving bed
0.726 0.274 0.000
F32.0 Mild depressive episode
0.726 0.274 0.000
I25.2 Old myocardial infarction
0.725 0.275 0.000
X50-X57 Overexertion, travel and privation
0.725 0.275 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.725 0.275 0.000
E88 Other metabolic disorders
0.724 0.276 0.000
G03.9 Meningitis, unspecified
0.723 0.277 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.722 0.278 0.000
W19.1 Residential institution
0.721 0.279 0.000
J42 Unspecified chronic bronchitis
0.720 0.280 0.000
B15-B19 Viral hepatitis
0.719 0.280 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.719 0.281 0.000
B00 Herpesviral [herpes simplex] infections
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
B01 Varicella [chickenpox]
0.716 0.284 0.000
T40.6 Other and unspecified narcotics
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
N20.0 Calculus of kidney
0.716 0.284 0.000
F38 Other mood [affective] disorders
0.716 0.284 0.000
F34 Persistent mood [affective] disorders
0.716 0.284 0.000
F39 Unspecified mood [affective] disorder
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.284 0.000
M25.57 Pain in joint (Ankle and foot)
0.715 0.285 0.000
N35.9 Urethral stricture, unspecified
0.715 0.285 0.000
J17 Pneumonia in diseases classified elsewhere
0.714 0.286 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.713 0.287 0.000
R47 Speech disturbances, not elsewhere classified
0.712 0.288 0.000
E11.8 With unspecified complications
0.711 0.289 0.000
E11.7 With multiple complications
0.711 0.289 0.000
E11.1 With ketoacidosis
0.711 0.289 0.000
E11.0 With coma
0.711 0.289 0.000
E10.1 With ketoacidosis
0.711 0.289 0.000
M24.5 Contracture of joint
0.710 0.290 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.709 0.291 0.000
Q35-Q37 Cleft lip and cleft palate
0.709 0.291 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.709 0.291 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.709 0.291 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.708 0.292 0.000
I23 Certain current complications following acute myocardial infarction
0.708 0.292 0.000
E29 Testicular dysfunction
0.707 0.292 0.000
S70 Superficial injury of hip and thigh
0.707 0.293 0.000
G51 Facial nerve disorders
0.707 0.293 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.706 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.706 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.706 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.706 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.706 0.293 0.000
T36 Poisoning by systemic antibiotics
0.706 0.293 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.706 0.294 0.000
I67.2 Cerebral atherosclerosis
0.706 0.294 0.000
F02 Dementia in other diseases classified elsewhere
0.704 0.296 0.000
E10.5 With peripheral circulatory complications
0.704 0.296 0.000
T98 Sequelae of other and unspecified effects of external causes
0.702 0.298 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.702 0.298 0.000
J44 Other chronic obstructive pulmonary disease
0.702 0.298 0.000
E24 Cushing's syndrome
0.702 0.298 0.000
Y43 Primarily systemic agents
0.702 0.298 0.000
J14 Pneumonia due to Haemophilus influenzae
0.702 0.298 0.000
M21.1 Varus deformity, not elsewhere classified
0.701 0.299 0.000
N04 Nephrotic syndrome
0.701 0.299 0.000
J60-J70 Lung diseases due to external agents
0.701 0.299 0.000
S82 Fracture of lower leg, including ankle
0.701 0.299 0.000
D60-D64 Aplastic and other anaemias
0.701 0.299 0.000
W13 Fall from, out of or through building or structure
0.700 0.300 0.000
S92 Fracture of foot, except ankle
0.700 0.300 0.000
S99 Other and unspecified injuries of ankle and foot
0.698 0.302 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.698 0.302 0.000
E16 Other disorders of pancreatic internal secretion
0.698 0.302 0.000
W17 Other fall from one level to another
0.698 0.302 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.698 0.302 0.000
W15 Fall from cliff
0.698 0.302 0.000
W14 Fall from tree
0.698 0.302 0.000
W12 Fall on and from scaffolding
0.698 0.302 0.000
W11 Fall on and from ladder
0.698 0.302 0.000
W09 Fall involving playground equipment
0.698 0.302 0.000
W05 Fall involving wheelchair
0.698 0.302 0.000
W04 Fall while being carried or supported by other persons
0.698 0.302 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.698 0.302 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.698 0.302 0.000
W00 Fall on same level involving ice and snow
0.698 0.302 0.000
S20-S29 Injuries to the thorax
0.698 0.302 0.000
I67.9 Cerebrovascular disease, unspecified
0.697 0.303 0.000
E85 Amyloidosis
0.697 0.303 0.000
E84 Cystic fibrosis
0.697 0.303 0.000
E79 Disorders of purine and pyrimidine metabolism
0.697 0.303 0.000
E77 Disorders of glycoprotein metabolism
0.697 0.303 0.000
E76 Disorders of glycosaminoglycan metabolism
0.697 0.303 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.697 0.303 0.000
E73 Lactose intolerance
0.697 0.303 0.000
E72 Other disorders of amino-acid metabolism
0.697 0.303 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.697 0.303 0.000
E70 Disorders of aromatic amino-acid metabolism
0.697 0.303 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.697 0.303 0.000
N71 Inflammatory disease of uterus, except cervix
0.697 0.303 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.697 0.303 0.000
I11 Hypertensive heart disease
0.696 0.304 0.000
R40 Somnolence, stupor and coma
0.696 0.304 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.696 0.304 0.000
B02.9 Zoster without complication
0.696 0.304 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.696 0.304 0.000
T66-T78 Other and unspecified effects of external causes
0.694 0.306 0.000
M24.1 Other articular cartilage disorders
0.694 0.306 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.694 0.306 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.693 0.307 0.000
M33 Dermatopolymyositis
0.693 0.307 0.000
M32 Systemic lupus erythematosus
0.693 0.307 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.693 0.307 0.000
F00 Dementia in Alzheimer's disease
0.692 0.308 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.691 0.309 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.691 0.309 0.000
N26 Unspecified contracted kidney
0.691 0.309 0.000
F31.8 Other bipolar affective disorders
0.690 0.310 0.000
F31.7 Bipolar affective disorder, currently in remission
0.690 0.310 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.690 0.310 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.690 0.310 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.690 0.310 0.000
M25.88 Other specified joint disorders (Other)
0.689 0.311 0.000
N28.0 Ischaemia and infarction of kidney
0.689 0.311 0.000
J21 Acute bronchiolitis
0.688 0.311 0.000
M25.0 Haemarthrosis
0.688 0.312 0.000
I24.8 Other forms of acute ischaemic heart disease
0.688 0.312 0.000
M47 Spondylosis
0.688 0.312 0.000
S78 Traumatic amputation of hip and thigh
0.687 0.313 0.000
S77 Crushing injury of hip and thigh
0.687 0.313 0.000
S75 Injury of blood vessels at hip and thigh level
0.687 0.313 0.000
S74 Injury of nerves at hip and thigh level
0.687 0.313 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.687 0.313 0.000
F32.8 Other depressive episodes
0.687 0.313 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.687 0.313 0.000
E83.8 Other disorders of mineral metabolism
0.687 0.313 0.000
E83.2 Disorders of zinc metabolism
0.687 0.313 0.000
E83.0 Disorders of copper metabolism
0.687 0.313 0.000
B99-B99 Other infectious diseases
0.687 0.313 0.000
X60-X84 Intentional self-harm
0.686 0.314 0.000
I25.6 Silent myocardial ischaemia
0.686 0.314 0.000
I25.4 Coronary artery aneurysm
0.686 0.314 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.686 0.314 0.000
G70-G73 Diseases of myoneural junction and muscle
0.685 0.315 0.000
B65-B83 Helminthiases
0.685 0.315 0.000
M91-M94 Chondropathies
0.685 0.315 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.684 0.315 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.684 0.316 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G92 Toxic encephalopathy
0.684 0.316 0.000
G30 Alzheimer's disease
0.684 0.316 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.684 0.316 0.000
F32.1 Moderate depressive episode
0.683 0.317 0.000
F33.8 Other recurrent depressive disorders
0.683 0.317 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.683 0.317 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.683 0.317 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.683 0.317 0.000
G82 Paraplegia and tetraplegia
0.683 0.317 0.000
B35-B49 Mycoses
0.682 0.318 0.000
N99.5 Malfunction of external stoma of urinary tract
0.682 0.318 0.000
M25.2 Flail joint
0.681 0.318 0.000
M25.1 Fistula of joint
0.681 0.318 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.681 0.319 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.681 0.319 0.000
G45.0 Vertebro-basilar artery syndrome
0.681 0.319 0.000
M70-M79 Other soft tissue disorders
0.681 0.319 0.000
Q64 Other congenital malformations of urinary system
0.681 0.319 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.681 0.319 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.681 0.319 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.681 0.319 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.680 0.320 0.000
Y52 Agents primarily affecting the cardiovascular system
0.680 0.320 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.679 0.321 0.000
I25.5 Ischaemic cardiomyopathy
0.679 0.321 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.679 0.321 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.678 0.321 0.000
B50-B64 Protozoal diseases
0.678 0.321 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.678 0.321 0.000
A75-A79 Rickettsioses
0.678 0.321 0.000
A70-A74 Other diseases caused by chlamydiae
0.678 0.321 0.000
A65-A69 Other spirochaetal diseases
0.678 0.321 0.000
A20-A28 Certain zoonotic bacterial diseases
0.678 0.321 0.000
A15-A19 Tuberculosis
0.678 0.321 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.678 0.321 0.000
B91 Sequelae of poliomyelitis
0.678 0.322 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.678 0.322 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.677 0.322 0.000
N06 Isolated proteinuria with specified morphological lesion
0.677 0.322 0.000
N01 Rapidly progressive nephritic syndrome
0.677 0.322 0.000
N00 Acute nephritic syndrome
0.677 0.322 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.677 0.323 0.000
N05 Unspecified nephritic syndrome
0.676 0.324 0.000
N02.8 Other
0.676 0.324 0.000
I65.2 Occlusion and stenosis of carotid artery
0.676 0.324 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.675 0.324 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.675 0.325 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.675 0.325 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.674 0.326 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.674 0.326 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.674 0.326 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.674 0.326 0.000
G00 Bacterial meningitis, not elsewhere classified
0.674 0.326 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.674 0.326 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.674 0.326 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.674 0.326 0.000
E10.8 With unspecified complications
0.673 0.327 0.000
E10.7 With multiple complications
0.673 0.327 0.000
E10.6 With other specified complications
0.673 0.327 0.000
E10.2 With renal complications
0.673 0.327 0.000
E10.0 With coma
0.673 0.327 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.673 0.327 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.673 0.327 0.000
J12 Viral pneumonia, not elsewhere classified
0.673 0.327 0.000
J09 Influenza due to certain identified influenza virus
0.673 0.327 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.672 0.327 0.000
N15 Other renal tubulo-interstitial diseases
0.672 0.327 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.672 0.327 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.672 0.328 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.672 0.328 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.672 0.328 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.672 0.328 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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