TreeWAS – Variant ID: rs17647114

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.987	0.013
Chapter XIV Diseases of the genitourinary system	0.985	0.015
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.983	0.017
N80-N98 Noninflammatory disorders of female genital tract	0.983	0.017
Chapter II Neoplasms	0.969	0.031
S00-S09 Injuries to the head	0.960	0.040
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.954	0.046
N85 Other noninflammatory disorders of uterus, except cervix	0.941	0.059
C50-C50 Malignant neoplasm of breast	0.916	0.084
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.906	0.094
D10-D36 Benign neoplasms	0.905	0.095
N84 Polyp of female genital tract	0.899	0.101
N85.2 Hypertrophy of uterus	0.898	0.102
Chapter XI Diseases of the digestive system	0.893	0.107
Chapter XV Pregnancy, childbirth and the puerperium	0.891	0.109
S01 Open wound of head	0.888	0.112
N70-N77 Inflammatory diseases of female pelvic organs	0.886	0.114
C50 Malignant neoplasm of breast	0.879	0.121
M20-M25 Other joint disorders	0.874	0.126
N80 Endometriosis	0.873	0.127
N86 Erosion and ectropion of cervix uteri	0.869	0.131
D17 Benign lipomatous neoplasm	0.859	0.141
Chapter XX External causes of morbidity and mortality	0.841	0.159
T36-T50 Poisoning by drugs, medicaments and biological substances	0.838	0.162
N20-N23 Urolithiasis	0.837	0.163
M25 Other joint disorders, not elsewhere classified	0.837	0.163
C51-C58 Malignant neoplasms of female genital organs	0.833	0.167
Chapter XII Diseases of the skin and subcutaneous tissue	0.832	0.168
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.825	0.175
N84.1 Polyp of cervix uteri	0.824	0.176
S00 Superficial injury of head	0.823	0.177
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.819	0.181
N83.2 Other and unspecified ovarian cysts	0.818	0.182
C50.9 Breast, unspecified	0.812	0.188
K70-K77 Diseases of liver	0.805	0.195
Chapter V Mental and behavioural disorders	0.805	0.195
S01.8 Open wound of other parts of head	0.801	0.199
S09 Other and unspecified injuries of head	0.798	0.202
M25.5 Pain in joint	0.798	0.202
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.798	0.202
C43-C44 Melanoma and other malignant neoplasms of skin	0.798	0.202
S40-S49 Injuries to the shoulder and upper arm	0.797	0.203
N72 Inflammatory disease of cervix uteri	0.794	0.206
N99-N99 Other disorders of the genitourinary system	0.793	0.206
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.793	0.207
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.789	0.211
N80.3 Endometriosis of pelvic peritoneum	0.789	0.211
N85.8 Other specified noninflammatory disorders of uterus	0.784	0.216
D25 Leiomyoma of uterus	0.782	0.217
M05-M14 Inflammatory polyarthropathies	0.782	0.218
M80-M85 Disorders of bone density and structure	0.782	0.218
M70-M79 Other soft tissue disorders	0.777	0.223
T66-T78 Other and unspecified effects of external causes	0.773	0.227
M25.56 Pain in joint (Lower leg)	0.771	0.229
C50.2 Upper-inner quadrant of breast	0.771	0.229
C64-C68 Malignant neoplasms of urinary tract	0.770	0.230
S50-S59 Injuries to the elbow and forearm	0.765	0.235
N10-N16 Renal tubulo-interstitial diseases	0.764	0.236
Chapter VII Diseases of the eye and adnexa	0.758	0.242
O60-O75 Complications of labour and delivery	0.749	0.251
L80-L99 Other disorders of the skin and subcutaneous tissue	0.745	0.255
N93 Other abnormal uterine and vaginal bleeding	0.744	0.256
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.743	0.257
S02 Fracture of skull and facial bones	0.742	0.258
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.742	0.258
W00-W19 Falls	0.741	0.259
N00-N08 Glomerular diseases	0.734	0.266
M65-M68 Disorders of synovium and tendon	0.734	0.266
S60-S69 Injuries to the wrist and hand	0.733	0.267
S01.5 Open wound of lip and oral cavity	0.728	0.272
T15-T19 Effects of foreign body entering through natural orifice	0.727	0.272
N20 Calculus of kidney and ureter	0.727	0.273
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.726	0.274
K40-K46 Hernia	0.724	0.276
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.723	0.277
Chapter VIII Diseases of the ear and mastoid process	0.721	0.279
M50-M54 Other dorsopathies	0.720	0.279
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.717	0.283
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.717	0.283
N88 Other noninflammatory disorders of cervix uteri	0.716	0.283
K86 Other diseases of pancreas	0.714	0.286
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.708	0.292
D27 Benign neoplasm of ovary	0.708	0.292
K83 Other diseases of biliary tract	0.708	0.292
D25.2 Subserosal leiomyoma of uterus	0.708	0.292
Chapter XXII Codes for special purposes	0.707	0.292
Chapter XVI Certain conditions originating in the perinatal period	0.707	0.292
C54 Malignant neoplasm of corpus uteri	0.707	0.293
T79-T79 Certain early complications of trauma	0.705	0.295
T33-T35 Frostbite	0.705	0.295
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.705	0.295
T26-T28 Burns and corrosions confined to eye and internal organs	0.705	0.295
T20-T25 Burns and corrosions of external body surface, specified by site	0.705	0.295
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.705	0.295
T00-T07 Injuries involving multiple body regions	0.705	0.295
S90-S99 Injuries to the ankle and foot	0.705	0.295
S10-S19 Injuries to the neck	0.705	0.295
N98 Complications associated with artificial fertilisation	0.705	0.295
N91 Absent, scanty and rare menstruation	0.705	0.295
N82 Fistulae involving female genital tract	0.705	0.295
N96 Habitual aborter	0.705	0.295
N90 Other noninflammatory disorders of vulva and perineum	0.704	0.296
K80 Cholelithiasis	0.704	0.296
S80-S89 Injuries to the knee and lower leg	0.704	0.296
M22 Disorders of patella	0.704	0.296
S00.8 Superficial injury of other parts of head	0.700	0.300
D37-D48 Neoplasms of uncertain or unknown behaviour	0.695	0.305
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.695	0.305
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.695	0.305
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.695	0.305
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.695	0.305
C40-C41 Malignant neoplasms of bone and articular cartilage	0.695	0.305
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.695	0.305
D00-D09 In situ neoplasms	0.694	0.306
N17-N19 Renal failure	0.694	0.306
N84.0 Polyp of corpus uteri	0.694	0.306
N83.0 Follicular cyst of ovary	0.694	0.306
S70-S79 Injuries to the hip and thigh	0.690	0.310
N94.6 Dysmenorrhoea, unspecified	0.689	0.311
D36 Benign neoplasm of other and unspecified sites	0.688	0.312
S08 Traumatic amputation of part of head	0.688	0.312
S07 Crushing injury of head	0.688	0.312
S06 Intracranial injury	0.688	0.312
S05 Injury of eye and orbit	0.688	0.312
S04 Injury of cranial nerves	0.688	0.312
S03 Dislocation, sprain and strain of joints and ligaments of head	0.688	0.312
M45-M49 Spondylopathies	0.686	0.314
M79 Other soft tissue disorders, not elsewhere classified	0.685	0.315
N87 Dysplasia of cervix uteri	0.685	0.315
S01.9 Open wound of head, part unspecified	0.684	0.315
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.684	0.316
M91-M94 Chondropathies	0.684	0.316
M86-M90 Other osteopathies	0.684	0.316
M60-M63 Disorders of muscles	0.684	0.316
M00-M03 Infectious arthropathies	0.684	0.316
S20-S29 Injuries to the thorax	0.684	0.316
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.683	0.316
N70 Salpingitis and oophoritis	0.683	0.317
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.683	0.317
N83.1 Corpus luteum cyst	0.683	0.317
S09.9 Unspecified injury of head	0.683	0.317
N25-N29 Other disorders of kidney and ureter	0.682	0.318
O80-O84 Delivery	0.681	0.319
N89 Other noninflammatory disorders of vagina	0.679	0.321
H25-H28 Disorders of lens	0.679	0.321
N81 Female genital prolapse	0.679	0.321
K76 Other diseases of liver	0.678	0.322
K50-K52 Noninfective enteritis and colitis	0.678	0.322
N21 Calculus of lower urinary tract	0.678	0.322
L40-L45 Papulosquamous disorders	0.677	0.323
O36 Maternal care for other known or suspected foetal problems	0.677	0.323
C15-C26 Malignant neoplasms of digestive organs	0.677	0.323
N85.9 Noninflammatory disorder of uterus, unspecified	0.674	0.326
N85.7 Haematometra	0.674	0.326
N85.6 Intra-uterine synechiae	0.674	0.326
N85.5 Inversion of uterus	0.674	0.326
N85.3 Subinvolution of uterus	0.674	0.326
N85.1 Endometrial adenomatous hyperplasia	0.674	0.326
K90-K93 Other diseases of the digestive system	0.674	0.326
W19 Unspecified fall	0.669	0.331
N80.1 Endometriosis of ovary	0.666	0.334
C43 Malignant melanoma of skin	0.664	0.336
D35 Benign neoplasm of other and unspecified endocrine glands	0.664	0.336
M35 Other systemic involvement of connective tissue	0.663	0.337
N95 Menopausal and other perimenopausal disorders	0.663	0.337
O48 Prolonged pregnancy	0.662	0.338
M25.8 Other specified joint disorders	0.660	0.340
K74 Fibrosis and cirrhosis of liver	0.659	0.341
C67 Malignant neoplasm of bladder	0.658	0.342
T93 Sequelae of injuries of lower limb	0.657	0.343
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.656	0.344
K43 Ventral hernia	0.656	0.344
D11 Benign neoplasm of major salivary glands	0.656	0.344
M40-M43 Deforming dorsopathies	0.655	0.345
M80 Osteoporosis with pathological fracture	0.655	0.345
D24 Benign neoplasm of breast	0.655	0.345
C50.1 Central portion of breast	0.653	0.347
O94-O99 Other obstetric conditions, not elsewhere classified	0.653	0.347
N85.4 Malposition of uterus	0.652	0.347
N80.0 Endometriosis of uterus	0.651	0.348
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.651	0.349
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.650	0.350
N83.7 Haematoma of broad ligament	0.650	0.350
N83.6 Haematosalpinx	0.650	0.350
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.650	0.350
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.650	0.350
N83.3 Acquired atrophy of ovary and Fallopian tube	0.650	0.350
C56 Malignant neoplasm of ovary	0.650	0.350
D33 Benign neoplasm of brain and other parts of central nervous system	0.649	0.351
D32 Benign neoplasm of meninges	0.649	0.351
D31 Benign neoplasm of eye and adnexa	0.649	0.351
D30 Benign neoplasm of urinary organs	0.649	0.351
D29 Benign neoplasm of male genital organs	0.649	0.351
D28 Benign neoplasm of other and unspecified female genital organs	0.649	0.351
D26 Other benign neoplasms of uterus	0.649	0.351
D21 Other benign neoplasms of connective and other soft tissue	0.649	0.351
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.649	0.351
D19 Benign neoplasm of mesothelial tissue	0.649	0.351
D16 Benign neoplasm of bone and articular cartilage	0.649	0.351
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.649	0.351
D14 Benign neoplasm of middle ear and respiratory system	0.649	0.351
D10 Benign neoplasm of mouth and pharynx	0.649	0.351
D34 Benign neoplasm of thyroid gland	0.649	0.351
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.648	0.352
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.645	0.355
N84.9 Polyp of female genital tract, unspecified	0.645	0.355
N84.8 Polyp of other parts of female genital tract	0.645	0.355
N84.3 Polyp of vulva	0.645	0.355
N84.2 Polyp of vagina	0.645	0.355
D22 Melanocytic naevi	0.644	0.356
M25.53 Pain in joint (Forearm)	0.644	0.356
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.644	0.356
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.643	0.356
N75 Diseases of Bartholin's gland	0.643	0.357
N85.0 Endometrial glandular hyperplasia	0.642	0.358
O32 Maternal care for known or suspected malpresentation of foetus	0.642	0.358
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.642	0.358
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.641	0.359
L92 Granulomatous disorders of skin and subcutaneous tissue	0.639	0.361
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.639	0.361
F00-F09 Organic, including symptomatic, mental disorders	0.639	0.361
O85-O92 Complications predominantly related to the puerperium	0.639	0.361
N73 Other female pelvic inflammatory diseases	0.638	0.362
S42 Fracture of shoulder and upper arm	0.637	0.363
S01.7 Multiple open wounds of head	0.637	0.363
S01.4 Open wound of cheek and temporomandibular area	0.637	0.363
S01.3 Open wound of ear	0.637	0.363
S01.2 Open wound of nose	0.637	0.363
S01.1 Open wound of eyelid and periocular area	0.637	0.363
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.635	0.365
N76 Other inflammation of vagina and vulva	0.635	0.365
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.635	0.365
N71 Inflammatory disease of uterus, except cervix	0.635	0.365
M07 Psoriatic and enteropathic arthropathies	0.634	0.366
K65-K67 Diseases of peritoneum	0.633	0.367
S00.0 Superficial injury of scalp	0.631	0.368
K70 Alcoholic liver disease	0.631	0.369
C50.8 Overlapping lesion of breast	0.630	0.370
C50.6 Axillary tail of breast	0.630	0.370
C50.5 Lower-outer quadrant of breast	0.630	0.370
C50.3 Lower-inner quadrant of breast	0.630	0.370
C50.0 Nipple and areola	0.630	0.370
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.630	0.370
L20-L30 Dermatitis and eczema	0.629	0.371
N20.0 Calculus of kidney	0.629	0.371
M24 Other specific joint derangements	0.628	0.371
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.627	0.373
M34 Systemic sclerosis	0.627	0.373
M33 Dermatopolymyositis	0.627	0.373
M32 Systemic lupus erythematosus	0.627	0.373
M31 Other necrotising vasculopathies	0.627	0.373
M30 Polyarteritis nodosa and related conditions	0.627	0.373
M21 Other acquired deformities of limbs	0.627	0.373
N80.8 Other endometriosis	0.626	0.374
N80.6 Endometriosis in cutaneous scar	0.626	0.374
N80.5 Endometriosis of intestine	0.626	0.374
N80.4 Endometriosis of rectovaginal septum and vagina	0.626	0.374
N80.2 Endometriosis of Fallopian tube	0.626	0.374
O46 Antepartum haemorrhage, not elsewhere classified	0.626	0.374
X60-X84 Intentional self-harm	0.625	0.375
K83.1 Obstruction of bile duct	0.625	0.375
M25.4 Effusion of joint	0.624	0.376
T78 Adverse effects, not elsewhere classified	0.623	0.377
M79.6 Pain in limb	0.622	0.378
N93.0 Postcoital and contact bleeding	0.622	0.378
C50.4 Upper-outer quadrant of breast	0.621	0.379
C54.1 Endometrium	0.617	0.383
D25.1 Intramural leiomyoma of uterus	0.616	0.384
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.616	0.384
D17.9 Benign lipomatous neoplasm, unspecified	0.616	0.384
D17.7 Benign lipomatous neoplasm of other sites	0.616	0.384
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.616	0.384
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.616	0.384
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.616	0.384
N97 Female infertility	0.615	0.385
D17.6 Benign lipomatous neoplasm of spermatic cord	0.613	0.387
L50-L54 Urticaria and erythema	0.613	0.387
L97 Ulcer of lower limb, not elsewhere classified	0.613	0.387
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.611	0.388
M70 Soft tissue disorders related to use, overuse and pressure	0.611	0.389
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.610	0.390
N60-N64 Disorders of breast	0.610	0.390
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.609	0.391
S52 Fracture of forearm	0.609	0.391
W19.9 Unspecified place	0.609	0.391
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.608	0.392
V10-V19 Pedal cyclist injured in transport accident	0.607	0.393
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.603	0.397
Y60-Y69 Misadventures to patients during surgical and medical care	0.603	0.397
Y35-Y36 Legal intervention and operations of war	0.603	0.397
Y10-Y34 Event of undetermined intent	0.603	0.397
Y00-Y09 Assault	0.603	0.397
X85-X99 Assault	0.603	0.397
X58-X59 Accidental exposure to other and unspecified factors	0.603	0.397
X50-X57 Overexertion, travel and privation	0.603	0.397
X40-X49 Accidental poisoning by and exposure to noxious substances	0.603	0.397
X30-X39 Exposure to forces of nature	0.603	0.397
X20-X29 Contact with venomous animals and plants	0.603	0.397
X10-X19 Contact with heat and hot substances	0.603	0.397
X00-X09 Exposure to smoke, fire and flames	0.603	0.397
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.603	0.397
W75-W84 Other accidental threats to breathing	0.603	0.397
W65-W74 Accidental drowning and submersion	0.603	0.397
W50-W64 Exposure to animate mechanical forces	0.603	0.397
W20-W49 Exposure to inanimate mechanical forces	0.603	0.397
V98-V99 Other and unspecified transport accidents	0.603	0.397
V95-V97 Air and space transport accidents	0.603	0.397
V90-V94 Water transport accidents	0.603	0.397
V80-V89 Other land transport accidents	0.603	0.397
V70-V79 Bus occupant injured in transport accident	0.603	0.397
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.603	0.397
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.603	0.397
V40-V49 Car occupant injured in transport accident	0.603	0.397
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.603	0.397
V20-V29 Motorcycle rider injured in transport accident	0.603	0.397
V01-V09 Pedestrian injured in transport accident	0.603	0.397
S01.0 Open wound of scalp	0.603	0.397
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.602	0.398
K86.8 Other specified diseases of pancreas	0.602	0.398
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.601	0.399
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.601	0.399
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.601	0.399
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.601	0.399
T46 Poisoning by agents primarily affecting the cardiovascular system	0.601	0.399
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.601	0.399
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.601	0.399
T41 Poisoning by anaesthetics and therapeutic gases	0.601	0.399
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.601	0.399
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.601	0.399
T36 Poisoning by systemic antibiotics	0.601	0.399
N22 Calculus of urinary tract in diseases classified elsewhere	0.600	0.400
M25.9 Joint disorder, unspecified	0.600	0.400
M25.6 Stiffness of joint, not elsewhere classified	0.600	0.400
M25.3 Other instability of joint	0.600	0.400
M25.2 Flail joint	0.600	0.400
M25.1 Fistula of joint	0.600	0.400
M25.0 Haemarthrosis	0.600	0.400
O75 Other complications of labour and delivery, not elsewhere classified	0.600	0.400
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.599	0.401
S00.9 Superficial injury of head, part unspecified	0.598	0.402
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.598	0.402
C57 Malignant neoplasm of other and unspecified female genital organs	0.597	0.403
C53 Malignant neoplasm of cervix uteri	0.597	0.403
C51 Malignant neoplasm of vulva	0.597	0.403
C58 Malignant neoplasm of placenta	0.597	0.403
C55 Malignant neoplasm of uterus, part unspecified	0.597	0.403
C52 Malignant neoplasm of vagina	0.597	0.403
L10-L14 Bullous disorders	0.597	0.403
L85 Other epidermal thickening	0.596	0.404
N94.1 Dyspareunia	0.596	0.404
D18 Haemangioma and lymphangioma, any site	0.596	0.404
K80.2 Calculus of gallbladder without cholecystitis	0.594	0.406
M05 Seropositive rheumatoid arthritis	0.594	0.406
S02.5 Fracture of tooth	0.593	0.407
K42 Umbilical hernia	0.593	0.407
M25.7 Osteophyte	0.593	0.407
M11 Other crystal arthropathies	0.592	0.408
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.592	0.408
K85 Acute pancreatitis	0.592	0.408
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.591	0.409
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.591	0.409
K50 Crohn's disease [regional enteritis]	0.590	0.410
S00.7 Multiple superficial injuries of head	0.590	0.410
S00.5 Superficial injury of lip and oral cavity	0.590	0.410
S00.4 Superficial injury of ear	0.590	0.410
S00.3 Superficial injury of nose	0.590	0.410
S00.2 Other superficial injuries of eyelid and periocular area	0.590	0.410
S00.1 Contusion of eyelid and periocular area	0.590	0.410
O69 Labour and delivery complicated by umbilical cord complications	0.590	0.410
C44 Other malignant neoplasms of skin	0.590	0.410
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.587	0.412
N94.5 Secondary dysmenorrhoea	0.587	0.412
N94.4 Primary dysmenorrhoea	0.587	0.412
N94.3 Premenstrual tension syndrome	0.587	0.412
N94.2 Vaginismus	0.587	0.412
N94.0 Mittelschmerz	0.587	0.412
M25.57 Pain in joint (Ankle and foot)	0.587	0.413
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.587	0.413
T39.1 4-Aminophenol derivatives	0.587	0.413
M23 Internal derangement of knee	0.585	0.415
O72 Postpartum haemorrhage	0.584	0.416
M15-M19 Arthrosis	0.584	0.416
M50 Cervical disk disorders	0.583	0.417
M22.4 Chondromalacia patellae	0.582	0.418
O66 Other obstructed labour	0.581	0.419
H53-H54 Visual disturbances and blindness	0.581	0.419
K76.6 Portal hypertension	0.579	0.421
M65 Synovitis and tenosynovitis	0.578	0.422
C67.9 Bladder, unspecified	0.578	0.422
H26 Other cataract	0.578	0.422
O68 Labour and delivery complicated by foetal stress [distress]	0.578	0.422
K77 Liver disorders in diseases classified elsewhere	0.577	0.422
K75 Other inflammatory liver diseases	0.577	0.422
K73 Chronic hepatitis, not elsewhere classified	0.577	0.422
K72 Hepatic failure, not elsewhere classified	0.577	0.422
K71 Toxic liver disease	0.577	0.422
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.577	0.423
F99-F99 Unspecified mental disorder	0.577	0.423
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.577	0.423
F80-F89 Disorders of psychological development	0.577	0.423
F70-F79 Mental retardation	0.577	0.423
F60-F69 Disorders of adult personality and behaviour	0.577	0.423
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.577	0.423
T85 Complications of other internal prosthetic devices, implants and grafts	0.577	0.423
K43.0 Ventral hernia with obstruction, without gangrene	0.576	0.424
C60-C63 Malignant neoplasms of male genital organs	0.575	0.425
H25 Senile cataract	0.573	0.427
S09.8 Other specified injuries of head	0.572	0.428
S09.7 Multiple injuries of head	0.572	0.428
S09.2 Traumatic rupture of ear drum	0.572	0.428
S09.1 Injury of muscle and tendon of head	0.572	0.428
S09.0 Injury of blood vessels of head, not elsewhere classified	0.572	0.428
M25.59 Pain in joint (Site unspecified)	0.572	0.428
M25.58 Pain in joint (Other)	0.572	0.428
M25.54 Pain in joint (Hand)	0.572	0.428
M25.52 Pain in joint (Upper arm)	0.572	0.428
M25.50 Pain in joint (Multiple sites)	0.572	0.428
O45 Premature separation of placenta [abruptio placentae]	0.572	0.428
O44 Placenta praevia	0.572	0.428
O43 Placental disorders	0.572	0.428
O41 Other disorders of amniotic fluid and membranes	0.572	0.428
O35 Maternal care for known or suspected foetal abnormality and damage	0.572	0.428
O33 Maternal care for known or suspected disproportion	0.572	0.428
O31 Complications specific to multiple gestation	0.572	0.428
O30 Multiple gestation	0.572	0.428
O40 Polyhydramnios	0.572	0.428
S49 Other and unspecified injuries of shoulder and upper arm	0.572	0.428
S48 Traumatic amputation of shoulder and upper arm	0.572	0.428
S46 Injury of muscle and tendon at shoulder and upper arm level	0.572	0.428
S45 Injury of blood vessels at shoulder and upper arm level	0.572	0.428
S44 Injury of nerves at shoulder and upper arm level	0.572	0.428
S41 Open wound of shoulder and upper arm	0.572	0.428
S40 Superficial injury of shoulder and upper arm	0.572	0.428
S47 Crushing injury of shoulder and upper arm	0.572	0.428
K86.1 Other chronic pancreatitis	0.571	0.429
K55-K64 Other diseases of intestines	0.571	0.429
M13 Other arthritis	0.570	0.430
M06 Other rheumatoid arthritis	0.569	0.431
T98 Sequelae of other and unspecified effects of external causes	0.569	0.431
T95 Sequelae of burns, corrosions and frostbite	0.569	0.431
T94 Sequelae of injuries involving multiple and unspecified body regions	0.569	0.431
T92 Sequelae of injuries of upper limb	0.569	0.431
T91 Sequelae of injuries of neck and trunk	0.569	0.431
T90 Sequelae of injuries of head	0.569	0.431
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.569	0.431
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.569	0.431
M25.51 Pain in joint (Shoulder region)	0.567	0.433
K76.8 Other specified diseases of liver	0.567	0.433
N80.9 Endometriosis, unspecified	0.567	0.433
S62 Fracture at wrist and hand level	0.567	0.433
Q20-Q28 Congenital malformations of the circulatory system	0.566	0.434
M79.66 Pain in limb (Lower leg)	0.566	0.434
O20-O29 Other maternal disorders predominantly related to pregnancy	0.566	0.434
M81 Osteoporosis without pathological fracture	0.565	0.435
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.565	0.435
M80.9 Unspecified osteoporosis with pathological fracture	0.564	0.436
N99.4 Postprocedural pelvic peritoneal adhesions	0.564	0.436
F40-F48 Neurotic, stress-related and somatoform disorders	0.564	0.436
N21.0 Calculus in bladder	0.563	0.437
D60-D64 Aplastic and other anaemias	0.562	0.438
M14 Arthropathies in other diseases classified elsewhere	0.561	0.439
M12 Other specific arthropathies	0.561	0.439
M09 Juvenile arthritis in diseases classified elsewhere	0.561	0.439
M08 Juvenile arthritis	0.561	0.439
L89 Decubitus ulcer	0.561	0.439
M85 Other disorders of bone density and structure	0.560	0.439
M84 Disorders of continuity of bone	0.560	0.439
M83 Adult osteomalacia	0.560	0.439
M82 Osteoporosis in diseases classified elsewhere	0.560	0.439
O00-O08 Pregnancy with abortive outcome	0.560	0.440
K35-K38 Diseases of appendix	0.559	0.441
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.558	0.441
O36.9 Maternal care for foetal problem, unspecified	0.558	0.442
K92 Other diseases of digestive system	0.558	0.442
M77 Other enthesopathies	0.557	0.443
M76 Enthesopathies of lower limb, excluding foot	0.557	0.443
M73 Soft tissue disorders in diseases classified elsewhere	0.557	0.443
M71 Other bursopathies	0.557	0.443
H60-H62 Diseases of external ear	0.556	0.443
T75 Effects of other external causes	0.555	0.445
T74 Maltreatment syndromes	0.555	0.445
T73 Effects of other deprivation	0.555	0.445
T70 Effects of air pressure and water pressure	0.555	0.445
T69 Other effects of reduced temperature	0.555	0.445
T67 Effects of heat and light	0.555	0.445
T71 Asphyxiation	0.555	0.445
T68 Hypothermia	0.555	0.445
T66 Unspecified effects of radiation	0.555	0.445
K74.6 Other and unspecified cirrhosis of liver	0.554	0.446
N03 Chronic nephritic syndrome	0.554	0.446
L40 Psoriasis	0.553	0.447
C68 Malignant neoplasm of other and unspecified urinary organs	0.552	0.448
C66 Malignant neoplasm of ureter	0.552	0.448
C65 Malignant neoplasm of renal pelvis	0.552	0.448
N20.2 Calculus of kidney with calculus of ureter	0.551	0.449
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.551	0.449
D50-D53 Nutritional anaemias	0.551	0.449
S59 Other and unspecified injuries of forearm	0.549	0.451
S58 Traumatic amputation of forearm	0.549	0.451
S57 Crushing injury of forearm	0.549	0.451

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations