TreeWAS – Variant ID: rs17854135

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter VIII Diseases of the ear and mastoid process	0.999	0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.993	0.007
Chapter VII Diseases of the eye and adnexa	0.989	0.011
Chapter XX External causes of morbidity and mortality	0.986	0.014
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.986	0.014
H25-H28 Disorders of lens	0.985	0.015
H26.9 Cataract, unspecified	0.984	0.016
H26 Other cataract	0.984	0.016
H60-H62 Diseases of external ear	0.980	0.020
H65-H75 Diseases of middle ear and mastoid	0.974	0.026
D70-D77 Other diseases of blood and blood-forming organs	0.968	0.032
S00-S09 Injuries to the head	0.964	0.036
S80-S89 Injuries to the knee and lower leg	0.944	0.056
H40-H42 Glaucoma	0.931	0.069
H61 Other disorders of external ear	0.929	0.071
Q20-Q28 Congenital malformations of the circulatory system	0.927	0.073
D70 Agranulocytosis	0.925	0.075
T20-T25 Burns and corrosions of external body surface, specified by site	0.922	0.078
Chapter VI Diseases of the nervous system	0.921	0.079
H90-H95 Other disorders of ear	0.919	0.081
H60 Otitis externa	0.907	0.093
S60-S69 Injuries to the wrist and hand	0.907	0.093
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.905	0.095
Chapter XV Pregnancy, childbirth and the puerperium	0.901	0.099
S02 Fracture of skull and facial bones	0.892	0.108
S40-S49 Injuries to the shoulder and upper arm	0.890	0.110
H40 Glaucoma	0.890	0.110
G30-G32 Other degenerative diseases of the nervous system	0.885	0.115
H72 Perforation of tympanic membrane	0.878	0.122
Q80-Q89 Other congenital malformations	0.878	0.122
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.873	0.127
Chapter II Neoplasms	0.872	0.128
S82 Fracture of lower leg, including ankle	0.868	0.132
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.867	0.133
K86 Other diseases of pancreas	0.866	0.134
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.865	0.135
Q21 Congenital malformations of cardiac septa	0.865	0.135
T15-T19 Effects of foreign body entering through natural orifice	0.864	0.136
W00-W19 Falls	0.864	0.136
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.863	0.137
D60-D64 Aplastic and other anaemias	0.862	0.138
K81 Cholecystitis	0.856	0.144
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.854	0.146
K82 Other diseases of gallbladder	0.854	0.146
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.853	0.147
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.853	0.147
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.852	0.148
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.850	0.150
D50-D53 Nutritional anaemias	0.850	0.150
H74 Other disorders of middle ear and mastoid	0.845	0.155
Chapter X Diseases of the respiratory system	0.844	0.156
W20-W49 Exposure to inanimate mechanical forces	0.839	0.161
H61.0 Perichondritis of external ear	0.838	0.162
G30 Alzheimer's disease	0.836	0.164
H90 Conductive and sensorineural hearing loss	0.829	0.171
Y43 Primarily systemic agents	0.828	0.172
S06 Intracranial injury	0.828	0.172
H69 Other disorders of Eustachian tube	0.827	0.173
S62 Fracture at wrist and hand level	0.826	0.174
K82.8 Other specified diseases of gallbladder	0.824	0.176
H40.9 Glaucoma, unspecified	0.823	0.177
C91 Lymphoid leukaemia	0.822	0.178
S09 Other and unspecified injuries of head	0.817	0.183
K81.0 Acute cholecystitis	0.817	0.183
J30-J39 Other diseases of upper respiratory tract	0.815	0.185
S82.2 Fracture of shaft of tibia	0.813	0.187
H53-H54 Visual disturbances and blindness	0.810	0.190
H61.2 Impacted cerumen	0.810	0.190
Y60-Y69 Misadventures to patients during surgical and medical care	0.809	0.191
T88 Other complications of surgical and medical care, not elsewhere classified	0.807	0.193
H60.1 Cellulitis of external ear	0.801	0.199
Chapter XXI Factors influencing health status and contact with health services	0.799	0.201
S80 Superficial injury of lower leg	0.797	0.203
T20 Burn and corrosion of head and neck	0.795	0.205
H10-H13 Disorders of conjunctiva	0.794	0.206
Q21.1 Atrial septal defect	0.793	0.207
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.793	0.207
S05 Injury of eye and orbit	0.791	0.209
J90-J94 Other diseases of pleura	0.788	0.212
D75 Other diseases of blood and blood-forming organs	0.787	0.213
K81.9 Cholecystitis, unspecified	0.786	0.214
Y43.3 Other antineoplastic drugs	0.786	0.214
C91.1 Chronic lymphocytic leukaemia	0.786	0.214
O20-O29 Other maternal disorders predominantly related to pregnancy	0.786	0.214
C92 Myeloid leukaemia	0.784	0.216
G30.9 Alzheimer's disease, unspecified	0.781	0.219
S01 Open wound of head	0.779	0.221
S82.20 Fracture of shaft of tibia (closed)	0.778	0.222
K85 Acute pancreatitis	0.778	0.222
Q23 Congenital malformations of aortic and mitral valves	0.776	0.223
W10 Fall on and from stairs and steps	0.776	0.224
Z40-Z54 Persons encountering health services for specific procedures and health care	0.775	0.225
H93 Other disorders of ear, not elsewhere classified	0.774	0.226
D62 Acute posthaemorrhagic anaemia	0.773	0.227
G63 Polyneuropathy in diseases classified elsewhere	0.771	0.229
W50-W64 Exposure to animate mechanical forces	0.771	0.229
K86.1 Other chronic pancreatitis	0.769	0.231
T79-T79 Certain early complications of trauma	0.769	0.231
C15-C26 Malignant neoplasms of digestive organs	0.769	0.231
K86.3 Pseudocyst of pancreas	0.768	0.232
Q50-Q56 Congenital malformations of genital organs	0.768	0.232
T85 Complications of other internal prosthetic devices, implants and grafts	0.768	0.232
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.768	0.232
Q38-Q45 Other congenital malformations of the digestive system	0.767	0.233
H73 Other disorders of tympanic membrane	0.766	0.234
H66 Suppurative and unspecified otitis media	0.765	0.235
K86.0 Alcohol-induced chronic pancreatitis	0.763	0.237
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.762	0.238
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.758	0.241
C50-C50 Malignant neoplasm of breast	0.758	0.242
T88.7 Unspecified adverse effect of drug or medicament	0.758	0.242
Y95 Nosocomial condition	0.758	0.242
Z42 Follow-up care involving plastic surgery	0.756	0.244
Y00-Y09 Assault	0.755	0.245
D68 Other coagulation defects	0.755	0.245
V20-V29 Motorcycle rider injured in transport accident	0.755	0.245
S02.1 Fracture of base of skull	0.754	0.246
S10-S19 Injuries to the neck	0.754	0.246
S62.6 Fracture of other finger	0.751	0.249
J34 Other disorders of nose and nasal sinuses	0.751	0.249
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.751	0.249
C43-C44 Melanoma and other malignant neoplasms of skin	0.750	0.250
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.750	0.250
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.749	0.251
G20-G26 Extrapyramidal and movement disorders	0.748	0.252
H40.1 Primary open-angle glaucoma	0.747	0.253
S40 Superficial injury of shoulder and upper arm	0.747	0.253
S64 Injury of nerves at wrist and hand level	0.746	0.254
T31 Burns classified according to extent of body surface involved	0.746	0.254
Q89 Other congenital malformations, not elsewhere classified	0.745	0.255
H60.9 Otitis externa, unspecified	0.744	0.256
H74.3 Other acquired abnormalities of ear ossicles	0.743	0.257
H72.8 Other perforations of tympanic membrane	0.743	0.257
J32 Chronic sinusitis	0.741	0.259
Chapter XI Diseases of the digestive system	0.741	0.259
D63 Anaemia in chronic diseases classified elsewhere	0.741	0.259
H72.9 Perforation of tympanic membrane, unspecified	0.741	0.259
X58-X59 Accidental exposure to other and unspecified factors	0.741	0.259
Chapter I Certain infectious and parasitic diseases	0.741	0.259
H71 Cholesteatoma of middle ear	0.740	0.260
S02.8 Fractures of other skull and facial bones	0.740	0.260
Z45 Adjustment and management of implanted device	0.740	0.260
H27 Other disorders of lens	0.739	0.261
H90.5 Sensorineural hearing loss, unspecified	0.738	0.262
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.737	0.262
D73 Diseases of spleen	0.737	0.263
Q60-Q64 Congenital malformations of the urinary system	0.736	0.264
Q00-Q07 Congenital malformations of the nervous system	0.736	0.264
X10-X19 Contact with heat and hot substances	0.736	0.264
T21 Burn and corrosion of trunk	0.736	0.264
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.735	0.265
S66 Injury of muscle and tendon at wrist and hand level	0.733	0.267
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.731	0.269
H70 Mastoiditis and related conditions	0.731	0.269
J95-J99 Other diseases of the respiratory system	0.729	0.271
S82.6 Fracture of lateral malleolus	0.729	0.271
H40.4 Glaucoma secondary to eye inflammation	0.728	0.271
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.727	0.273
K86.8 Other specified diseases of pancreas	0.727	0.273
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.726	0.274
K82.9 Disease of gallbladder, unspecified	0.726	0.274
K86.2 Cyst of pancreas	0.726	0.274
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.725	0.275
V40-V49 Car occupant injured in transport accident	0.724	0.275
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.721	0.279
V80-V89 Other land transport accidents	0.720	0.279
G00-G09 Inflammatory diseases of the central nervous system	0.720	0.280
T16 Foreign body in ear	0.718	0.282
H26.1 Traumatic cataract	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S70-S79 Injuries to the hip and thigh	0.717	0.283
S01.8 Open wound of other parts of head	0.715	0.285
T86 Failure and rejection of transplanted organs and tissues	0.714	0.286
Z47 Other orthopaedic follow-up care	0.713	0.287
Z42.0 Follow-up care involving plastic surgery of head and neck	0.713	0.287
G61 Inflammatory polyneuropathy	0.713	0.287
O80-O84 Delivery	0.713	0.287
G63.2 Diabetic polyneuropathy	0.712	0.288
Q21.0 Ventricular septal defect	0.711	0.289
K82.4 Cholesterolosis of gallbladder	0.710	0.290
S41 Open wound of shoulder and upper arm	0.709	0.291
J34.2 Deviated nasal septum	0.709	0.291
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.709	0.291
H60.8 Other otitis externa	0.708	0.292
Y35-Y36 Legal intervention and operations of war	0.707	0.293
Y10-Y34 Event of undetermined intent	0.707	0.293
X85-X99 Assault	0.707	0.293
X50-X57 Overexertion, travel and privation	0.707	0.293
X30-X39 Exposure to forces of nature	0.707	0.293
X20-X29 Contact with venomous animals and plants	0.707	0.293
X00-X09 Exposure to smoke, fire and flames	0.707	0.293
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.707	0.293
W75-W84 Other accidental threats to breathing	0.707	0.293
W65-W74 Accidental drowning and submersion	0.707	0.293
V98-V99 Other and unspecified transport accidents	0.707	0.293
V95-V97 Air and space transport accidents	0.707	0.293
V90-V94 Water transport accidents	0.707	0.293
V70-V79 Bus occupant injured in transport accident	0.707	0.293
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.707	0.293
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.707	0.293
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.707	0.293
V01-V09 Pedestrian injured in transport accident	0.707	0.293
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.707	0.293
Q35-Q37 Cleft lip and cleft palate	0.707	0.293
Q30-Q34 Congenital malformations of the respiratory system	0.707	0.293
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.707	0.293
D72 Other disorders of white blood cells	0.707	0.293
T23 Burn and corrosion of wrist and hand	0.706	0.293
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.706	0.294
O94-O99 Other obstetric conditions, not elsewhere classified	0.706	0.294
H26.3 Drug-induced cataract	0.705	0.294
H26.0 Infantile, juvenile and presenile cataract	0.705	0.294
C25 Malignant neoplasm of pancreas	0.705	0.295
Y41 Other systemic anti-infectives and antiparasitics	0.704	0.296
K83 Other diseases of biliary tract	0.703	0.297
H62 Disorders of external ear in diseases classified elsewhere	0.703	0.297
S82.0 Fracture of patella	0.701	0.299
H61.3 Acquired stenosis of external ear canal	0.699	0.301
J36 Peritonsillar abscess	0.699	0.301
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.698	0.302
H68 Eustachian salpingitis and obstruction	0.698	0.302
H67 Otitis media in diseases classified elsewhere	0.698	0.302
C92.0 Acute myeloid leukaemia	0.698	0.302
H72.2 Other marginal perforations of tympanic membrane	0.697	0.303
T94 Sequelae of injuries involving multiple and unspecified body regions	0.697	0.303
C20 Malignant neoplasm of rectum	0.696	0.304
W44 Foreign body entering into or through eye or natural orifice	0.695	0.305
D74 Methaemoglobinaemia	0.694	0.306
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.694	0.306
D71 Functional disorders of polymorphonuclear neutrophils	0.694	0.306
V10-V19 Pedal cyclist injured in transport accident	0.693	0.307
S69 Other and unspecified injuries of wrist and hand	0.692	0.308
D55-D59 Haemolytic anaemias	0.692	0.308
S08 Traumatic amputation of part of head	0.691	0.308
S07 Crushing injury of head	0.691	0.308
S04 Injury of cranial nerves	0.691	0.308
S03 Dislocation, sprain and strain of joints and ligaments of head	0.691	0.308
H26.4 After-cataract	0.690	0.310
H46-H48 Disorders of optic nerve and visual pathways	0.689	0.311
X40-X49 Accidental poisoning by and exposure to noxious substances	0.689	0.311
S02.0 Fracture of vault of skull	0.688	0.311
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.688	0.312
H69.9 Eustachian tube disorder, unspecified	0.688	0.312
G30.0 Alzheimer's disease with early onset	0.688	0.312
Chapter V Mental and behavioural disorders	0.687	0.313
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.687	0.313
Z43 Attention to artificial openings	0.687	0.313
W10.8 Other specified place	0.687	0.313
Q82 Other congenital malformations of skin	0.686	0.314
S86 Injury of muscle and tendon at lower leg level	0.685	0.315
W21 Striking against or struck by sports equipment	0.685	0.315
G90-G99 Other disorders of the nervous system	0.685	0.315
H26.2 Complicated cataract	0.685	0.315
Y52 Agents primarily affecting the cardiovascular system	0.684	0.316
S80.9 Superficial injury of lower leg, unspecified	0.684	0.316
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.683	0.317
D37-D48 Neoplasms of uncertain or unknown behaviour	0.683	0.317
S02.6 Fracture of mandible	0.683	0.317
C90 Multiple myeloma and malignant plasma cell neoplasms	0.682	0.317
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.682	0.318
S49 Other and unspecified injuries of shoulder and upper arm	0.682	0.318
Z45.2 Adjustment and management of vascular access device	0.682	0.318
H93.9 Disorder of ear, unspecified	0.681	0.319
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.679	0.321
H53 Visual disturbances	0.678	0.322
D50 Iron deficiency anaemia	0.677	0.323
S88 Traumatic amputation of lower leg	0.677	0.323
S87 Crushing injury of lower leg	0.677	0.323
S85 Injury of blood vessels at lower leg level	0.677	0.323
S84 Injury of nerves at lower leg level	0.677	0.323
C50 Malignant neoplasm of breast	0.676	0.324
T66-T78 Other and unspecified effects of external causes	0.676	0.324
T18 Foreign body in alimentary tract	0.675	0.325
W07 Fall involving chair	0.674	0.326
X60-X84 Intentional self-harm	0.673	0.327
G80-G83 Cerebral palsy and other paralytic syndromes	0.672	0.327
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.672	0.328
S06.3 Focal brain injury	0.672	0.328
O23 Infections of genito-urinary tract in pregnancy	0.670	0.330
Z42.1 Follow-up care involving plastic surgery of breast	0.670	0.330
T31.0 Burns involving less than 10% of body surface	0.670	0.330
C44 Other malignant neoplasms of skin	0.670	0.330
S02.2 Fracture of nasal bones	0.669	0.331
T20.1 Burn of first degree of head and neck	0.669	0.331
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.669	0.331
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.669	0.331
H42 Glaucoma in diseases classified elsewhere	0.668	0.332
D51 Vitamin B12 deficiency anaemia	0.668	0.332
J32.9 Chronic sinusitis, unspecified	0.667	0.333
S02.3 Fracture of orbital floor	0.667	0.333
H61.9 Disorder of external ear, unspecified	0.666	0.334
H61.8 Other specified disorders of external ear	0.666	0.334
K83.1 Obstruction of bile duct	0.666	0.334
Q26 Congenital malformations of great veins	0.665	0.335
Q25 Congenital malformations of great arteries	0.665	0.335
Q24 Other congenital malformations of heart	0.665	0.335
Q22 Congenital malformations of pulmonary and tricuspid valves	0.665	0.335
Q20 Congenital malformations of cardiac chambers and connexions	0.665	0.335
T88.5 Other complications of anaesthesia	0.665	0.335
H61.1 Non-infective disorders of pinna	0.664	0.336
T87 Complications peculiar to reattachment and amputation	0.664	0.336
S09.9 Unspecified injury of head	0.663	0.337
S62.8 Fracture of other and unspecified parts of wrist and hand	0.663	0.337
H90.0 Conductive hearing loss, bilateral	0.662	0.338
Q27 Other congenital malformations of peripheral vascular system	0.661	0.339
K85.1 Biliary acute pancreatitis	0.661	0.339
T25 Burn and corrosion of ankle and foot	0.661	0.339
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.661	0.339
H40.0 Glaucoma suspect	0.661	0.339
J90 Pleural effusion, not elsewhere classified	0.661	0.339
D52 Folate deficiency anaemia	0.660	0.340
S09.8 Other specified injuries of head	0.660	0.340
D69 Purpura and other haemorrhagic conditions	0.660	0.340
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.659	0.341
S50-S59 Injuries to the elbow and forearm	0.659	0.341
T91 Sequelae of injuries of neck and trunk	0.659	0.341
H94 Other disorders of ear in diseases classified elsewhere	0.659	0.341
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.658	0.342
S06.5 Traumatic subdural haemorrhage	0.658	0.342
H40.8 Other glaucoma	0.658	0.342
Q85 Phakomatoses, not elsewhere classified	0.657	0.343
B15-B19 Viral hepatitis	0.656	0.344
S02.10 Fracture of base of skull (closed)	0.656	0.344
J31.0 Chronic rhinitis	0.654	0.346
Y44 Agents primarily affecting blood constituents	0.654	0.346
O85-O92 Complications predominantly related to the puerperium	0.654	0.346
S62.61 Fracture of other finger (open)	0.652	0.348
T17 Foreign body in respiratory tract	0.652	0.348
J93 Pneumothorax	0.651	0.349
H60.5 Acute otitis externa, non-infective	0.650	0.349
H60.4 Cholesteatoma of external ear	0.650	0.349
H60.3 Other infective otitis externa	0.650	0.349
H60.2 Malignant otitis externa	0.650	0.349
H60.0 Abscess of external ear	0.650	0.349
S65 Injury of blood vessels at wrist and hand level	0.650	0.350
H69.8 Other specified disorders of Eustachian tube	0.650	0.350
Q89.2 Congenital malformations of other endocrine glands	0.650	0.350
K85.9 Acute pancreatitis, unspecified	0.649	0.350
Y59 Other and unspecified vaccines and biological substances	0.649	0.351
Y58 Bacterial vaccines	0.649	0.351
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.649	0.351
Y53 Agents primarily affecting the gastro-intestinal system	0.649	0.351
Y50 Central nervous system stimulants, not elsewhere classified	0.649	0.351
Y49 Psychotropic drugs, not elsewhere classified	0.649	0.351
Y48 Anaesthetics and therapeutic gases	0.649	0.351
Y47 Sedatives, hypnotics and antianxiety drugs	0.649	0.351
Y46 Antiepileptics and anti-Parkinsonism drugs	0.649	0.351
S89 Other and unspecified injuries of lower leg	0.649	0.351
J94 Other pleural conditions	0.648	0.352
S06.8 Other intracranial injuries	0.647	0.353
G31.8 Other specified degenerative diseases of nervous system	0.647	0.353
J33 Nasal polyp	0.646	0.354
G70-G73 Diseases of myoneural junction and muscle	0.645	0.355
S05.1 Contusion of eyeball and orbital tissues	0.645	0.355
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.644	0.356
G24 Dystonia	0.643	0.357
B35-B49 Mycoses	0.643	0.357
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.643	0.357
C50.3 Lower-inner quadrant of breast	0.642	0.358
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.642	0.358
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.642	0.358
S02.9 Fracture of skull and facial bones, part unspecified	0.639	0.361
S02.7 Multiple fractures involving skull and facial bones	0.639	0.361
H55-H59 Other disorders of eye and adnexa	0.639	0.361
D75.9 Disease of blood and blood-forming organs, unspecified	0.639	0.361
S46 Injury of muscle and tendon at shoulder and upper arm level	0.639	0.361
S48 Traumatic amputation of shoulder and upper arm	0.638	0.362
S45 Injury of blood vessels at shoulder and upper arm level	0.638	0.362
S44 Injury of nerves at shoulder and upper arm level	0.638	0.362
S47 Crushing injury of shoulder and upper arm	0.638	0.362
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.638	0.362
H40.6 Glaucoma secondary to drugs	0.638	0.362
H40.3 Glaucoma secondary to eye trauma	0.638	0.362
C92.1 Chronic myeloid leukaemia	0.638	0.362
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.637	0.363
H74.4 Polyp of middle ear	0.637	0.363
W06 Fall involving bed	0.637	0.363
Z45.1 Adjustment and management of infusion pump	0.637	0.363
S62.60 Fracture of other finger (closed)	0.636	0.364
S40.0 Contusion of shoulder and upper arm	0.636	0.364
C25.0 Head of pancreas	0.636	0.364
D50.8 Other iron deficiency anaemias	0.635	0.365
S81 Open wound of lower leg	0.635	0.365
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.634	0.365
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.634	0.366
S64.4 Injury of digital nerve of other finger	0.633	0.367
S02.5 Fracture of tooth	0.633	0.367
Chapter XXII Codes for special purposes	0.632	0.368
S20-S29 Injuries to the thorax	0.632	0.368
S02.80 Fractures of other skull and facial bones (closed)	0.631	0.369
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.631	0.369
T20.2 Burn of second degree of head and neck	0.631	0.369
H72.1 Attic perforation of tympanic membrane	0.630	0.370
W17 Other fall from one level to another	0.630	0.370
H40.2 Primary angle-closure glaucoma	0.630	0.370
W29 Contact with other powered hand tools and household machinery	0.630	0.370
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.630	0.370
Q84 Other congenital malformations of integument	0.630	0.370
Q83 Congenital malformations of breast	0.630	0.370
Q81 Epidermolysis bullosa	0.630	0.370
Q80 Congenital ichthyosis	0.630	0.370
S82.60 Fracture of lateral malleolus (closed)	0.630	0.370
T93 Sequelae of injuries of lower limb	0.629	0.371
C91.4 Hairy-cell leukaemia	0.629	0.371
C44.1 Skin of eyelid, including canthus	0.628	0.372
H10 Conjunctivitis	0.628	0.372
T92 Sequelae of injuries of upper limb	0.628	0.372
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.627	0.373
Q28 Other congenital malformations of circulatory system	0.627	0.373
T86.8 Failure and rejection of other transplanted organs and tissues	0.627	0.373
Z34 Supervision of normal pregnancy	0.627	0.373
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.626	0.374
T90 Sequelae of injuries of head	0.625	0.375
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.625	0.375
C40-C41 Malignant neoplasms of bone and articular cartilage	0.625	0.375
O14.9 Preeclampsia, unspecified	0.625	0.375
Q23.1 Congenital insufficiency of aortic valve	0.625	0.375
H53.2 Diplopia	0.625	0.375
D63.0 Anaemia in neoplastic disease	0.624	0.376
S62.3 Fracture of other metacarpal bone	0.623	0.377
Z70-Z76 Persons encountering health services in other circumstances	0.623	0.377
K86.9 Disease of pancreas, unspecified	0.622	0.378
J92 Pleural plaque	0.622	0.378
S82.9 Fracture of lower leg, part unspecified	0.622	0.378
S82.7 Multiple fractures of lower leg	0.622	0.378
W49 Exposure to other and unspecified inanimate mechanical forces	0.622	0.378
W08 Fall involving other furniture	0.620	0.379
D67 Hereditary factor IX deficiency	0.620	0.380
D66 Hereditary factor VIII deficiency	0.620	0.380
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.620	0.380
Q21.9 Congenital malformation of cardiac septum, unspecified	0.620	0.380
Q21.8 Other congenital malformations of cardiac septa	0.620	0.380
Q21.4 Aortopulmonary septal defect	0.620	0.380
Q21.3 Tetralogy of Fallot	0.620	0.380
Q21.2 Atrioventricular septal defect	0.620	0.380
D68.9 Coagulation defect, unspecified	0.620	0.380
S06.4 Epidural haemorrhage	0.620	0.380
Q23.0 Congenital stenosis of aortic valve	0.620	0.380
T19 Foreign body in genito-urinary tract	0.619	0.380
T15 Foreign body on external eye	0.619	0.380
W10.4 Street and highway	0.619	0.381
W16 Diving or jumping into water causing injury other than drowning or submersion	0.619	0.381
W15 Fall from cliff	0.619	0.381
W14 Fall from tree	0.619	0.381
W12 Fall on and from scaffolding	0.619	0.381
W11 Fall on and from ladder	0.619	0.381
W09 Fall involving playground equipment	0.619	0.381
W05 Fall involving wheelchair	0.619	0.381
W04 Fall while being carried or supported by other persons	0.619	0.381
W03 Other fall on same level due to collision with, or pushing by, another person	0.619	0.381
W01 Fall on same level from slipping, tripping and stumbling	0.619	0.381
W00 Fall on same level involving ice and snow	0.619	0.381
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.619	0.381
C95 Leukaemia of unspecified cell type	0.619	0.381
C94 Other leukaemias of specified cell type	0.619	0.381
C93 Monocytic leukaemia	0.619	0.381
C88 Malignant immunoproliferative diseases	0.619	0.381
C86 Other specified types of T/NK-cell lymphoma	0.619	0.381
C84 Peripheral and cutaneous T-cell lymphomas	0.619	0.381
S01.9 Open wound of head, part unspecified	0.619	0.381
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.618	0.382
H90.2 Conductive hearing loss, unspecified	0.618	0.382
C81 Hodgkin's disease	0.617	0.383
S68 Traumatic amputation of wrist and hand	0.617	0.383
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.617	0.383
H73.8 Other specified disorders of tympanic membrane	0.616	0.384
Q51 Congenital malformations of uterus and cervix	0.616	0.384
T98 Sequelae of other and unspecified effects of external causes	0.615	0.385
K81.8 Other cholecystitis	0.614	0.386
Z36 Antenatal screening	0.614	0.386
Q43 Other congenital malformations of intestine	0.613	0.387
T95 Sequelae of burns, corrosions and frostbite	0.613	0.387
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.613	0.387
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.613	0.387
K82.3 Fistula of gallbladder	0.612	0.388
K82.2 Perforation of gallbladder	0.612	0.388
K82.0 Obstruction of gallbladder	0.612	0.388
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.612	0.388
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.612	0.388
Y91 Evidence of alcohol involvement determined by level of intoxication	0.612	0.388
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.612	0.388
Y98 Lifestyle-related condition	0.612	0.388
Y97 Environmental-pollution-related condition	0.612	0.388
Y96 Work-related condition	0.612	0.388
G60 Hereditary and idiopathic neuropathy	0.611	0.388
G64 Other disorders of peripheral nervous system	0.611	0.388
T32 Corrosions classified according to extent of body surface involved	0.611	0.389
T30 Burn and corrosion, body region unspecified	0.611	0.389
T29 Burns and corrosions of multiple body regions	0.611	0.389
C50.5 Lower-outer quadrant of breast	0.611	0.389
Z48 Other surgical follow-up care	0.610	0.390
D61 Other aplastic anaemias	0.610	0.390
S90-S99 Injuries to the ankle and foot	0.609	0.390
S01.3 Open wound of ear	0.610	0.390
O15 Eclampsia	0.609	0.391

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations