TreeWAS – Variant ID: rs1800750

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000
E10.9 Without complications	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter II Neoplasms	1.000	0.000
E03 Other hypothyroidism	1.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000
K62.1 Rectal polyp	0.999	0.001
K55-K64 Other diseases of intestines	0.999	0.001
K62 Other diseases of anus and rectum	0.999	0.001
Chapter VII Diseases of the eye and adnexa	0.998	0.002
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.997	0.003
D10-D36 Benign neoplasms	0.997	0.003
H30-H36 Disorders of choroid and retina	0.996	0.004
K90-K93 Other diseases of the digestive system	0.995	0.005
E10.3 With ophthalmic complications	0.994	0.006
H36 Retinal disorders in diseases classified elsewhere	0.993	0.007
K40-K46 Hernia	0.993	0.007
K90 Intestinal malabsorption	0.992	0.008
Chapter VI Diseases of the nervous system	0.992	0.008
H36.0 Diabetic retinopathy	0.991	0.009
K90.0 Coeliac disease	0.991	0.009
G35-G37 Demyelinating diseases of the central nervous system	0.989	0.011
Chapter V Mental and behavioural disorders	0.988	0.012
G35 Multiple sclerosis	0.988	0.012
D12.5 Sigmoid colon	0.978	0.022
C43-C44 Melanoma and other malignant neoplasms of skin	0.974	0.026
K44 Diaphragmatic hernia	0.969	0.031
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.967	0.033
E10.4 With neurological complications	0.955	0.045
D12.6 Colon, unspecified	0.954	0.046
Chapter XX External causes of morbidity and mortality	0.953	0.047
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.951	0.049
S50-S59 Injuries to the elbow and forearm	0.950	0.050
C15-C26 Malignant neoplasms of digestive organs	0.947	0.053
F30-F39 Mood [affective] disorders	0.943	0.057
S40-S49 Injuries to the shoulder and upper arm	0.941	0.059
C44 Other malignant neoplasms of skin	0.939	0.061
S60-S69 Injuries to the wrist and hand	0.932	0.068
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.930	0.070
D12.3 Transverse colon	0.930	0.070
E10.1 With ketoacidosis	0.930	0.070
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.929	0.071
K63 Other diseases of intestine	0.927	0.073
K62.3 Rectal prolapse	0.926	0.074
Chapter I Certain infectious and parasitic diseases	0.913	0.087
S52 Fracture of forearm	0.911	0.089
E14 Unspecified diabetes mellitus	0.908	0.092
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.905	0.095
D12.8 Rectum	0.904	0.096
S42 Fracture of shoulder and upper arm	0.903	0.097
D60-D64 Aplastic and other anaemias	0.901	0.098
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.900	0.100
K41 Femoral hernia	0.900	0.100
K63.5 Polyp of colon	0.898	0.102
K42 Umbilical hernia	0.880	0.120
E16 Other disorders of pancreatic internal secretion	0.878	0.122
S80-S89 Injuries to the knee and lower leg	0.871	0.129
T81 Complications of procedures, not elsewhere classified	0.867	0.133
D64 Other anaemias	0.867	0.133
T66-T78 Other and unspecified effects of external causes	0.864	0.136
S20-S29 Injuries to the thorax	0.862	0.138
C44.1 Skin of eyelid, including canthus	0.861	0.139
S52.6 Fracture of lower end of both ulna and radius	0.855	0.145
F32 Depressive episode	0.855	0.145
W00-W19 Falls	0.854	0.146
H25-H28 Disorders of lens	0.853	0.147
Chapter XIV Diseases of the genitourinary system	0.848	0.152
D12.2 Ascending colon	0.848	0.152
D26 Other benign neoplasms of uterus	0.846	0.154
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.844	0.156
D64.9 Anaemia, unspecified	0.843	0.157
E16.2 Hypoglycaemia, unspecified	0.842	0.158
E07 Other disorders of thyroid	0.835	0.165
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.833	0.167
K55 Vascular disorders of intestine	0.832	0.167
C43 Malignant melanoma of skin	0.831	0.169
N32.8 Other specified disorders of bladder	0.827	0.173
D37-D48 Neoplasms of uncertain or unknown behaviour	0.826	0.174
N30-N39 Other diseases of urinary system	0.826	0.174
E14.9 Without complications	0.825	0.175
C44.7 Skin of lower limb, including hip	0.824	0.176
N32 Other disorders of bladder	0.823	0.177
H35 Other retinal disorders	0.822	0.178
C50-C50 Malignant neoplasm of breast	0.818	0.182
B35-B49 Mycoses	0.816	0.184
E10.5 With peripheral circulatory complications	0.816	0.184
S52.60 Fracture of lower end of both ulna and radius (closed)	0.815	0.185
S60 Superficial injury of wrist and hand	0.815	0.185
K35-K38 Diseases of appendix	0.812	0.188
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.810	0.190
T85 Complications of other internal prosthetic devices, implants and grafts	0.808	0.192
C44.5 Skin of trunk	0.803	0.197
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.803	0.197
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.803	0.197
H34 Retinal vascular occlusions	0.803	0.197
C15 Malignant neoplasm of oesophagus	0.801	0.199
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.801	0.199
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.801	0.199
A00-A09 Intestinal infectious diseases	0.801	0.199
T88 Other complications of surgical and medical care, not elsewhere classified	0.798	0.202
K70-K77 Diseases of liver	0.798	0.202
F31 Bipolar affective disorder	0.794	0.206
S42.1 Fracture of scapula	0.792	0.208
K42.9 Umbilical hernia without obstruction or gangrene	0.791	0.209
T83.1 Mechanical complication of other urinary devices and implants	0.790	0.210
C44.4 Skin of scalp and neck	0.788	0.212
H26 Other cataract	0.787	0.213
Chapter IX Diseases of the circulatory system	0.787	0.213
T36-T50 Poisoning by drugs, medicaments and biological substances	0.786	0.214
K43 Ventral hernia	0.783	0.217
F17 Mental and behavioural disorders due to use of tobacco	0.782	0.218
F10 Mental and behavioural disorders due to use of alcohol	0.781	0.219
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.779	0.221
T81.8 Other complications of procedures, not elsewhere classified	0.779	0.221
D36 Benign neoplasm of other and unspecified sites	0.777	0.223
H55-H59 Other disorders of eye and adnexa	0.776	0.224
S42.2 Fracture of upper end of humerus	0.775	0.225
D32 Benign neoplasm of meninges	0.775	0.225
D21 Other benign neoplasms of connective and other soft tissue	0.774	0.226
G70-G73 Diseases of myoneural junction and muscle	0.774	0.226
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.772	0.227
W19 Unspecified fall	0.770	0.230
S42.0 Fracture of clavicle	0.769	0.231
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.769	0.231
F33 Recurrent depressive disorder	0.768	0.232
T78 Adverse effects, not elsewhere classified	0.767	0.233
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.767	0.233
T79-T79 Certain early complications of trauma	0.763	0.237
D17 Benign lipomatous neoplasm	0.763	0.237
S82 Fracture of lower leg, including ankle	0.762	0.238
D24 Benign neoplasm of breast	0.762	0.238
D12.4 Descending colon	0.761	0.239
E13 Other specified diabetes mellitus	0.760	0.240
H46-H48 Disorders of optic nerve and visual pathways	0.760	0.240
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.759	0.241
E11 Non-insulin-dependent diabetes mellitus	0.756	0.244
T83.0 Mechanical complication of urinary (indwelling) catheter	0.753	0.247
S66 Injury of muscle and tendon at wrist and hand level	0.752	0.248
Chapter XXII Codes for special purposes	0.752	0.248
S64 Injury of nerves at wrist and hand level	0.751	0.249
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.750	0.250
D14 Benign neoplasm of middle ear and respiratory system	0.750	0.250
E05 Thyrotoxicosis [hyperthyroidism]	0.748	0.252
K55.2 Angiodysplasia of colon	0.748	0.252
S61 Open wound of wrist and hand	0.747	0.253
S52.1 Fracture of upper end of radius	0.747	0.253
X20-X29 Contact with venomous animals and plants	0.746	0.254
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.745	0.255
T15-T19 Effects of foreign body entering through natural orifice	0.744	0.256
K61 Abscess of anal and rectal regions	0.743	0.256
K83 Other diseases of biliary tract	0.742	0.258
D62 Acute posthaemorrhagic anaemia	0.741	0.259
D00-D09 In situ neoplasms	0.739	0.261
C25 Malignant neoplasm of pancreas	0.739	0.261
F60-F69 Disorders of adult personality and behaviour	0.739	0.261
F32.9 Depressive episode, unspecified	0.737	0.263
C64-C68 Malignant neoplasms of urinary tract	0.736	0.264
H43-H45 Disorders of vitreous body and globe	0.736	0.264
N25-N29 Other disorders of kidney and ureter	0.735	0.265
H26.4 After-cataract	0.734	0.266
G30-G32 Other degenerative diseases of the nervous system	0.733	0.267
Chapter VIII Diseases of the ear and mastoid process	0.733	0.267
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.732	0.268
E65-E68 Obesity and other hyperalimentation	0.732	0.268
S52.5 Fracture of lower end of radius	0.732	0.268
A04 Other bacterial intestinal infections	0.730	0.270
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.729	0.271
C19 Malignant neoplasm of rectosigmoid junction	0.729	0.271
E20-E35 Disorders of other endocrine glands	0.729	0.271
H10-H13 Disorders of conjunctiva	0.727	0.273
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.726	0.274
N10-N16 Renal tubulo-interstitial diseases	0.726	0.274
C44.0 Skin of lip	0.726	0.274
D10 Benign neoplasm of mouth and pharynx	0.725	0.275
F32.2 Severe depressive episode without psychotic symptoms	0.724	0.276
F10.2 Dependence syndrome	0.724	0.276
E11.3 With ophthalmic complications	0.723	0.277
G90-G99 Other disorders of the nervous system	0.722	0.278
E06 Thyroiditis	0.720	0.280
F99-F99 Unspecified mental disorder	0.720	0.280
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.720	0.280
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.719	0.281
C26 Malignant neoplasm of other and ill-defined digestive organs	0.718	0.282
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.718	0.282
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.718	0.282
E07.9 Disorder of thyroid, unspecified	0.718	0.282
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
E10.2 With renal complications	0.717	0.283
E10.0 With coma	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.717	0.283
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.717	0.283
E03.8 Other specified hypothyroidism	0.717	0.283
E03.5 Myxoedema coma	0.717	0.283
E03.4 Atrophy of thyroid (acquired)	0.717	0.283
E03.3 Postinfectious hypothyroidism	0.717	0.283
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283
E03.1 Congenital hypothyroidism without goitre	0.717	0.283
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283
E00 Congenital iodine-deficiency syndrome	0.717	0.283
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283
S90-S99 Injuries to the ankle and foot	0.716	0.283
K64 Haemorrhoids and perianal venous thrombosis	0.716	0.283
K62.6 Ulcer of anus and rectum	0.716	0.284
K62.4 Stenosis of anus and rectum	0.716	0.284
K62.2 Anal prolapse	0.716	0.284
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.716	0.284
C51-C58 Malignant neoplasms of female genital organs	0.715	0.285
D12.9 Anus and anal canal	0.715	0.285
D12.1 Appendix	0.715	0.285
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.715	0.285
D31 Benign neoplasm of eye and adnexa	0.715	0.285
D30 Benign neoplasm of urinary organs	0.715	0.285
D29 Benign neoplasm of male genital organs	0.715	0.285
D28 Benign neoplasm of other and unspecified female genital organs	0.715	0.285
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.715	0.285
D19 Benign neoplasm of mesothelial tissue	0.715	0.285
D16 Benign neoplasm of bone and articular cartilage	0.715	0.285
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.715	0.285
D34 Benign neoplasm of thyroid gland	0.715	0.285
H32 Chorioretinal disorders in diseases classified elsewhere	0.714	0.286
H31 Other disorders of choroid	0.714	0.286
H30 Chorioretinal inflammation	0.714	0.286
C43.4 Malignant melanoma of scalp and neck	0.714	0.286
K93 Disorders of other digestive organs in diseases classified elsewhere	0.713	0.286
F17.1 Harmful use	0.713	0.287
G50-G59 Nerve, nerve root and plexus disorders	0.713	0.287
K62.7 Radiation proctitis	0.713	0.287
B37 Candidiasis	0.712	0.287
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.712	0.288
S42.10 Fracture of scapula (closed)	0.712	0.288
H36.8 Other retinal disorders in diseases classified elsewhere	0.712	0.288
K45 Other abdominal hernia	0.712	0.288
D50-D53 Nutritional anaemias	0.712	0.288
K90.9 Intestinal malabsorption, unspecified	0.711	0.288
K90.8 Other intestinal malabsorption	0.711	0.288
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.711	0.288
K90.3 Pancreatic steatorrhoea	0.711	0.288
K90.2 Blind loop syndrome, not elsewhere classified	0.711	0.288
K90.1 Tropical sprue	0.711	0.288
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.711	0.288
G00-G09 Inflammatory diseases of the central nervous system	0.711	0.288
V20-V29 Motorcycle rider injured in transport accident	0.711	0.289
G36 Other acute disseminated demyelination	0.709	0.291
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.708	0.292
F80-F89 Disorders of psychological development	0.708	0.292
F70-F79 Mental retardation	0.708	0.292
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.708	0.292
S22 Fracture of rib(s), sternum and thoracic spine	0.708	0.292
W20-W49 Exposure to inanimate mechanical forces	0.706	0.294
N00-N08 Glomerular diseases	0.705	0.295
H40-H42 Glaucoma	0.705	0.295
E14.3 With ophthalmic complications	0.704	0.296
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.704	0.296
D27 Benign neoplasm of ovary	0.704	0.296
G37 Other demyelinating diseases of central nervous system	0.703	0.297
F00-F09 Organic, including symptomatic, mental disorders	0.701	0.299
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.700	0.300
C24.0 Extrahepatic bile duct	0.697	0.303
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.697	0.303
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.697	0.303
D33 Benign neoplasm of brain and other parts of central nervous system	0.696	0.304
S50 Superficial injury of forearm	0.696	0.304
T93 Sequelae of injuries of lower limb	0.696	0.304
K44.1 Diaphragmatic hernia with gangrene	0.694	0.305
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.694	0.305
D26.0 Cervix uteri	0.694	0.306
K63.2 Fistula of intestine	0.694	0.306
D12.7 Rectosigmoid junction	0.693	0.306
T87 Complications peculiar to reattachment and amputation	0.693	0.307
T86 Failure and rejection of transplanted organs and tissues	0.693	0.307
T80 Complications following infusion, transfusion and therapeutic injection	0.693	0.307
K46 Unspecified abdominal hernia	0.693	0.307
N99-N99 Other disorders of the genitourinary system	0.692	0.308
S60.8 Other superficial injuries of wrist and hand	0.691	0.309
F40-F48 Neurotic, stress-related and somatoform disorders	0.691	0.309
C50 Malignant neoplasm of breast	0.687	0.313
I95-I99 Other and unspecified disorders of the circulatory system	0.687	0.313
F31.9 Bipolar affective disorder, unspecified	0.687	0.313
D61 Other aplastic anaemias	0.686	0.314
A30-A49 Other bacterial diseases	0.684	0.316
K62.0 Anal polyp	0.684	0.316
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.684	0.316
Y35-Y36 Legal intervention and operations of war	0.683	0.317
Y10-Y34 Event of undetermined intent	0.683	0.317
Y00-Y09 Assault	0.683	0.317
X85-X99 Assault	0.683	0.317
X58-X59 Accidental exposure to other and unspecified factors	0.683	0.317
X50-X57 Overexertion, travel and privation	0.683	0.317
X40-X49 Accidental poisoning by and exposure to noxious substances	0.683	0.317
X30-X39 Exposure to forces of nature	0.683	0.317
X10-X19 Contact with heat and hot substances	0.683	0.317
X00-X09 Exposure to smoke, fire and flames	0.683	0.317
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.683	0.317
W75-W84 Other accidental threats to breathing	0.683	0.317
W65-W74 Accidental drowning and submersion	0.683	0.317
W50-W64 Exposure to animate mechanical forces	0.683	0.317
V98-V99 Other and unspecified transport accidents	0.683	0.317
V95-V97 Air and space transport accidents	0.683	0.317
V90-V94 Water transport accidents	0.683	0.317
V80-V89 Other land transport accidents	0.683	0.317
V70-V79 Bus occupant injured in transport accident	0.683	0.317
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.683	0.317
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.683	0.317
V40-V49 Car occupant injured in transport accident	0.683	0.317
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.683	0.317
V01-V09 Pedestrian injured in transport accident	0.683	0.317
S42.20 Fracture of upper end of humerus (closed)	0.683	0.317
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.682	0.318
S59 Other and unspecified injuries of forearm	0.681	0.319
S58 Traumatic amputation of forearm	0.681	0.319
S57 Crushing injury of forearm	0.681	0.319
S56 Injury of muscle and tendon at forearm level	0.681	0.319
S55 Injury of blood vessels at forearm level	0.681	0.319
S54 Injury of nerves at forearm level	0.681	0.319
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.681	0.319
S51 Open wound of forearm	0.681	0.319
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.679	0.321
C21 Malignant neoplasm of anus and anal canal	0.679	0.321
C17 Malignant neoplasm of small intestine	0.679	0.321
C23 Malignant neoplasm of gallbladder	0.679	0.321
T88.7 Unspecified adverse effect of drug or medicament	0.677	0.323
F38 Other mood [affective] disorders	0.676	0.324
F34 Persistent mood [affective] disorders	0.676	0.324
F30 Manic episode	0.676	0.324
F39 Unspecified mood [affective] disorder	0.676	0.324
T78.4 Allergy, unspecified	0.676	0.324
S49 Other and unspecified injuries of shoulder and upper arm	0.675	0.325
S48 Traumatic amputation of shoulder and upper arm	0.675	0.325
S46 Injury of muscle and tendon at shoulder and upper arm level	0.675	0.325
S45 Injury of blood vessels at shoulder and upper arm level	0.675	0.325
S44 Injury of nerves at shoulder and upper arm level	0.675	0.325
S41 Open wound of shoulder and upper arm	0.675	0.325
S40 Superficial injury of shoulder and upper arm	0.675	0.325
S47 Crushing injury of shoulder and upper arm	0.675	0.325
D26.1 Corpus uteri	0.675	0.325
S27 Injury of other and unspecified intrathoracic organs	0.674	0.326
D11 Benign neoplasm of major salivary glands	0.674	0.326
V10-V19 Pedal cyclist injured in transport accident	0.674	0.326
S42.00 Fracture of clavicle (closed)	0.674	0.326
C44.9 Malignant neoplasm of skin, unspecified	0.673	0.327
C44.8 Overlapping lesion of skin	0.673	0.327
X60-X84 Intentional self-harm	0.673	0.327
W19.9 Unspecified place	0.670	0.330
K65-K67 Diseases of peritoneum	0.670	0.330
S69 Other and unspecified injuries of wrist and hand	0.668	0.331
S67 Crushing injury of wrist and hand	0.668	0.331
S65 Injury of blood vessels at wrist and hand level	0.668	0.331
C44.2 Skin of ear and external auricular canal	0.668	0.332
D55-D59 Haemolytic anaemias	0.667	0.333
H33 Retinal detachments and breaks	0.667	0.333
E15 Nondiabetic hypoglycaemic coma	0.666	0.334
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.665	0.335
Y60-Y69 Misadventures to patients during surgical and medical care	0.664	0.335
K63.4 Enteroptosis	0.664	0.335
K63.0 Abscess of intestine	0.664	0.335
H34.8 Other retinal vascular occlusions	0.664	0.336
K70 Alcoholic liver disease	0.663	0.337
C15.9 Oesophagus, unspecified	0.662	0.338
S80 Superficial injury of lower leg	0.661	0.339
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.661	0.339
B35 Dermatophytosis	0.660	0.340
C43.5 Malignant melanoma of trunk	0.660	0.340
S20 Superficial injury of thorax	0.659	0.341
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.659	0.341
C34 Malignant neoplasm of bronchus and lung	0.659	0.341
N17-N19 Renal failure	0.659	0.341
Q20-Q28 Congenital malformations of the circulatory system	0.658	0.342
S42.3 Fracture of shaft of humerus	0.657	0.342
S60.9 Superficial injury of wrist and hand, unspecified	0.657	0.343
C18 Malignant neoplasm of colon	0.657	0.343
A04.8 Other specified bacterial intestinal infections	0.656	0.344
S42.4 Fracture of lower end of humerus	0.656	0.344
B99-B99 Other infectious diseases	0.655	0.345
B90-B94 Sequelae of infectious and parasitic diseases	0.655	0.345
B85-B89 Pediculosis, acariasis and other infestations	0.655	0.345
B65-B83 Helminthiases	0.655	0.345
B50-B64 Protozoal diseases	0.655	0.345
B20-B24 Human immunodeficiency virus [HIV] disease	0.655	0.345
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.655	0.345
A80-A89 Viral infections of the central nervous system	0.655	0.345
A75-A79 Rickettsioses	0.655	0.345
A70-A74 Other diseases caused by chlamydiae	0.655	0.345
A65-A69 Other spirochaetal diseases	0.655	0.345
A50-A64 Infections with a predominantly sexual mode of transmission	0.655	0.345
A20-A28 Certain zoonotic bacterial diseases	0.655	0.345
A15-A19 Tuberculosis	0.655	0.345
T90 Sequelae of injuries of head	0.654	0.345
K42.0 Umbilical hernia with obstruction, without gangrene	0.654	0.345
N28 Other disorders of kidney and ureter, not elsewhere classified	0.654	0.346
S52.9 Fracture of forearm, part unspecified	0.653	0.347
S52.8 Fracture of other parts of forearm	0.653	0.347
S52.7 Multiple fractures of forearm	0.653	0.347
S52.4 Fracture of shafts of both ulna and radius	0.653	0.347
S52.3 Fracture of shaft of radius	0.653	0.347
S52.2 Fracture of shaft of ulna	0.653	0.347
K43.0 Ventral hernia with obstruction, without gangrene	0.653	0.347
C20 Malignant neoplasm of rectum	0.653	0.347
W10 Fall on and from stairs and steps	0.652	0.348
B37.0 Candidal stomatitis	0.652	0.348
E14.8 With unspecified complications	0.651	0.349
E14.7 With multiple complications	0.651	0.349
E14.6 With other specified complications	0.651	0.349
E14.5 With peripheral circulatory complications	0.651	0.349
E14.4 With neurological complications	0.651	0.349
E14.2 Withrenal complications	0.651	0.349
E14.1 With ketoacidosis	0.651	0.349
E14.0 With coma	0.651	0.349
B15-B19 Viral hepatitis	0.650	0.349
C44.6 Skin of upper limb, including shoulder	0.650	0.350
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.649	0.351
F18 Mental and behavioural disorders due to use of volatile solvents	0.649	0.351
F16 Mental and behavioural disorders due to use of hallucinogens	0.649	0.351
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.649	0.351
F14 Mental and behavioural disorders due to use of cocaine	0.649	0.351
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.649	0.351
F12 Mental and behavioural disorders due to use of cannabinoids	0.649	0.351
F11 Mental and behavioural disorders due to use of opioids	0.649	0.351
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.648	0.352
C22.1 Intrahepatic bile duct carcinoma	0.648	0.352
S42.9 Fracture of shoulder girdle, part unspecified	0.648	0.352
S42.8 Fracture of other parts of shoulder and upper arm	0.648	0.352
S42.7 Multiple fractures of clavicle, scapula and humerus	0.648	0.352
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.646	0.354
Y86 Sequelae of other accidents	0.646	0.354
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.645	0.355
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.645	0.355
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.645	0.355
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.645	0.355
T83.3 Mechanical complication of intra-uterine contraceptive device	0.645	0.355
T83.2 Mechanical complication of graft of urinary organ	0.645	0.355
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.645	0.355
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.645	0.355
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.645	0.355
K41.1 Bilateral femoral hernia, with gangrene	0.645	0.355
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.645	0.355
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.645	0.355
K86 Other diseases of pancreas	0.645	0.355
F33.9 Recurrent depressive disorder, unspecified	0.643	0.357
D36.7 Other specified sites	0.641	0.358
K63.9 Disease of intestine, unspecified	0.641	0.359
A08 Viral and other specified intestinal infections	0.641	0.359
S70-S79 Injuries to the hip and thigh	0.641	0.359
G80-G83 Cerebral palsy and other paralytic syndromes	0.641	0.359
H35.6 Retinal haemorrhage	0.639	0.360
K63.1 Perforation of intestine (nontraumatic)	0.639	0.361
K35 Acute appendicitis	0.638	0.362
S62 Fracture at wrist and hand level	0.637	0.363
W19.1 Residential institution	0.637	0.363
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.636	0.364
K57 Diverticular disease of intestine	0.636	0.364
N32.3 Diverticulum of bladder	0.636	0.364
K62.9 Disease of anus and rectum, unspecified	0.635	0.365
K37 Unspecified appendicitis	0.634	0.366
C16 Malignant neoplasm of stomach	0.633	0.367
I30-I52 Other forms of heart disease	0.633	0.367
K83.0 Cholangitis	0.632	0.368
C15.5 Lower third of oesophagus	0.632	0.368
T81.3 Disruption of operation wound, not elsewhere classified	0.632	0.368
K42.1 Umbilical hernia with gangrene	0.631	0.369
E16.9 Disorder of pancreatic internal secretion, unspecified	0.629	0.370
E16.8 Other specified disorders of pancreatic internal secretion	0.629	0.370
E16.4 Abnormal secretion of gastrin	0.629	0.370
E16.3 Increased secretion of glucagon	0.629	0.370
E16.1 Other hypoglycaemia	0.629	0.370
E16.0 Drug-induced hypoglycaemia without coma	0.629	0.370
S52.10 Fracture of upper end of radius (closed)	0.629	0.371
H35.3 Degeneration of macula and posterior pole	0.628	0.372
S52.0 Fracture of upper end of ulna	0.628	0.372
S82.2 Fracture of shaft of tibia	0.628	0.372
S82.8 Fractures of other parts of lower leg	0.627	0.373
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.626	0.374
S89 Other and unspecified injuries of lower leg	0.625	0.375
S88 Traumatic amputation of lower leg	0.625	0.375
S87 Crushing injury of lower leg	0.625	0.375
S86 Injury of muscle and tendon at lower leg level	0.625	0.375
S85 Injury of blood vessels at lower leg level	0.625	0.375
S84 Injury of nerves at lower leg level	0.625	0.375
S81 Open wound of lower leg	0.625	0.375
S82.3 Fracture of lower end of tibia	0.624	0.375
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.624	0.376

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations