TreeWAS – Variant ID: rs181705462

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
K55-K64 Other diseases of intestines	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
# Top node	1.000	0.000
K57 Diverticular disease of intestine	1.000	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	1.000	0.000
Chapter II Neoplasms	1.000	0.000
D10-D36 Benign neoplasms	0.999	0.001
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.996	0.004
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.995	0.005
K56 Paralytic ileus and intestinal obstruction without hernia	0.989	0.011
K56.6 Other and unspecified intestinal obstruction	0.978	0.022
K63 Other diseases of intestine	0.977	0.023
K83 Other diseases of biliary tract	0.976	0.024
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.971	0.029
Chapter IX Diseases of the circulatory system	0.969	0.031
Chapter XX External causes of morbidity and mortality	0.960	0.040
K65-K67 Diseases of peritoneum	0.960	0.040
Chapter XIV Diseases of the genitourinary system	0.955	0.045
K80 Cholelithiasis	0.954	0.046
D12.5 Sigmoid colon	0.951	0.049
I60-I69 Cerebrovascular diseases	0.949	0.051
Chapter VII Diseases of the eye and adnexa	0.938	0.062
D12.2 Ascending colon	0.929	0.071
K50-K52 Noninfective enteritis and colitis	0.929	0.071
Chapter XV Pregnancy, childbirth and the puerperium	0.926	0.074
Chapter XII Diseases of the skin and subcutaneous tissue	0.925	0.075
K66 Other disorders of peritoneum	0.925	0.075
K83.8 Other specified diseases of biliary tract	0.922	0.078
K63.8 Other specified diseases of intestine	0.922	0.078
Chapter XXI Factors influencing health status and contact with health services	0.915	0.085
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.903	0.097
D23 Other benign neoplasms of skin	0.902	0.098
D22 Melanocytic naevi	0.902	0.098
N17-N19 Renal failure	0.900	0.100
K66.0 Peritoneal adhesions	0.900	0.100
K70-K77 Diseases of liver	0.896	0.104
I30-I52 Other forms of heart disease	0.894	0.106
K50 Crohn's disease [regional enteritis]	0.893	0.107
I70-I79 Diseases of arteries, arterioles and capillaries	0.892	0.108
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.889	0.111
L80-L99 Other disorders of the skin and subcutaneous tissue	0.889	0.111
N25-N29 Other disorders of kidney and ureter	0.884	0.116
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.884	0.116
D12.3 Transverse colon	0.874	0.126
I67 Other cerebrovascular diseases	0.872	0.128
Z00-Z13 Persons encountering health services for examination and investigation	0.869	0.131
D24 Benign neoplasm of breast	0.869	0.131
K80.1 Calculus of gallbladder with other cholecystitis	0.868	0.132
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.863	0.137
I63 Cerebral infarction	0.861	0.139
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.859	0.141
I60 Subarachnoid haemorrhage	0.855	0.145
K83.0 Cholangitis	0.854	0.146
Chapter VI Diseases of the nervous system	0.850	0.150
K57.1 Diverticular disease of small intestine without perforation or abscess	0.849	0.151
I44 Atrioventricular and left bundle-branch block	0.849	0.151
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.848	0.152
H30-H36 Disorders of choroid and retina	0.848	0.152
K63.5 Polyp of colon	0.842	0.158
S70-S79 Injuries to the hip and thigh	0.842	0.158
O60-O75 Complications of labour and delivery	0.839	0.161
K55 Vascular disorders of intestine	0.838	0.162
N28 Other disorders of kidney and ureter, not elsewhere classified	0.834	0.166
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.832	0.168
N60-N64 Disorders of breast	0.830	0.170
S60-S69 Injuries to the wrist and hand	0.828	0.172
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.820	0.180
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.819	0.181
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.818	0.182
N18 Chronic renal failure	0.816	0.184
D23.3 Skin of other and unspecified parts of face	0.814	0.186
D12.8 Rectum	0.813	0.187
Z08 Follow-up examination after treatment for malignant neoplasm	0.812	0.188
K63.3 Ulcer of intestine	0.809	0.191
K83.1 Obstruction of bile duct	0.806	0.194
L97 Ulcer of lower limb, not elsewhere classified	0.805	0.195
I44.0 Atrioventricular block, first degree	0.805	0.195
I71 Aortic aneurysm and dissection	0.804	0.195
H40-H42 Glaucoma	0.802	0.198
L40-L45 Papulosquamous disorders	0.801	0.199
D21 Other benign neoplasms of connective and other soft tissue	0.801	0.199
I67.9 Cerebrovascular disease, unspecified	0.797	0.203
D32 Benign neoplasm of meninges	0.796	0.204
N30-N39 Other diseases of urinary system	0.794	0.206
H33 Retinal detachments and breaks	0.793	0.207
K86 Other diseases of pancreas	0.792	0.208
I77 Other disorders of arteries and arterioles	0.791	0.209
D23.6 Skin of upper limb, including shoulder	0.790	0.210
Chapter I Certain infectious and parasitic diseases	0.790	0.210
Z03 Medical observation and evaluation for suspected diseases and conditions	0.790	0.210
I95-I99 Other and unspecified disorders of the circulatory system	0.789	0.211
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.787	0.212
K50.0 Crohn's disease of small intestine	0.785	0.215
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.785	0.215
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.783	0.217
K57.2 Diverticular disease of large intestine with perforation and abscess	0.781	0.219
H43-H45 Disorders of vitreous body and globe	0.780	0.220
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.775	0.225
N10-N16 Renal tubulo-interstitial diseases	0.773	0.227
G35-G37 Demyelinating diseases of the central nervous system	0.771	0.229
D36 Benign neoplasm of other and unspecified sites	0.769	0.231
D18 Haemangioma and lymphangioma, any site	0.767	0.233
K59 Other functional intestinal disorders	0.767	0.233
K85 Acute pancreatitis	0.767	0.233
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.767	0.233
D12.0 Caecum	0.766	0.234
I47 Paroxysmal tachycardia	0.765	0.235
N17 Acute renal failure	0.764	0.236
O63 Long labour	0.762	0.238
T15-T19 Effects of foreign body entering through natural orifice	0.760	0.240
C15-C26 Malignant neoplasms of digestive organs	0.760	0.240
K50.9 Crohn's disease, unspecified	0.760	0.240
A00-A09 Intestinal infectious diseases	0.760	0.240
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.759	0.241
N99-N99 Other disorders of the genitourinary system	0.759	0.241
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.758	0.242
Z04 Examination and observation for other reasons	0.758	0.242
K63.1 Perforation of intestine (nontraumatic)	0.757	0.243
K56.2 Volvulus	0.757	0.243
K80.8 Other cholelithiasis	0.754	0.246
V10-V19 Pedal cyclist injured in transport accident	0.754	0.246
C51-C58 Malignant neoplasms of female genital organs	0.753	0.247
Chapter XXII Codes for special purposes	0.753	0.247
S90-S99 Injuries to the ankle and foot	0.751	0.249
D00-D09 In situ neoplasms	0.751	0.249
N30 Cystitis	0.750	0.250
I63.9 Cerebral infarction, unspecified	0.750	0.250
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.749	0.251
K61 Abscess of anal and rectal regions	0.748	0.252
K80.2 Calculus of gallbladder without cholecystitis	0.747	0.253
L92 Granulomatous disorders of skin and subcutaneous tissue	0.746	0.254
K56.4 Other impaction of intestine	0.746	0.254
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.746	0.254
S50-S59 Injuries to the elbow and forearm	0.745	0.255
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.744	0.256
N28.8 Other specified disorders of kidney and ureter	0.744	0.256
S80-S89 Injuries to the knee and lower leg	0.743	0.256
D22.7 Melanocytic naevi of lower limb, including hip	0.742	0.258
Y83.6 Removal of other organ (partial) (total)	0.739	0.261
C64-C68 Malignant neoplasms of urinary tract	0.738	0.262
K65 Peritonitis	0.736	0.264
C80 Malignant neoplasm without specification of site	0.736	0.264
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.735	0.265
K58 Irritable bowel syndrome	0.735	0.265
I60.9 Subarachnoid haemorrhage, unspecified	0.734	0.266
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.734	0.266
Z22 Carrier of infectious disease	0.734	0.266
Z12 Special screening examination for neoplasms	0.733	0.267
L89 Decubitus ulcer	0.732	0.268
L81 Other disorders of pigmentation	0.731	0.269
D22.4 Melanocytic naevi of scalp and neck	0.730	0.270
C60-C63 Malignant neoplasms of male genital organs	0.729	0.271
K50.8 Other Crohn's disease	0.729	0.271
Chapter V Mental and behavioural disorders	0.728	0.272
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.725	0.275
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.725	0.275
Y86 Sequelae of other accidents	0.724	0.276
H55-H59 Other disorders of eye and adnexa	0.723	0.277
K63.2 Fistula of intestine	0.722	0.278
C34 Malignant neoplasm of bronchus and lung	0.722	0.278
N64 Other disorders of breast	0.722	0.278
K50.1 Crohn's disease of large intestine	0.721	0.278
C50-C50 Malignant neoplasm of breast	0.721	0.279
Z03.4 Observation for suspected myocardial infarction	0.720	0.280
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.720	0.280
K74 Fibrosis and cirrhosis of liver	0.720	0.280
D23.5 Skin of trunk	0.719	0.281
K76 Other diseases of liver	0.719	0.281
I61 Intracerebral haemorrhage	0.719	0.281
L40 Psoriasis	0.718	0.282
I50 Heart failure	0.717	0.283
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.717	0.283
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.717	0.283
K57.0 Diverticular disease of small intestine with perforation and abscess	0.717	0.283
K64 Haemorrhoids and perianal venous thrombosis	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
D33 Benign neoplasm of brain and other parts of central nervous system	0.716	0.283
D31 Benign neoplasm of eye and adnexa	0.716	0.283
D30 Benign neoplasm of urinary organs	0.716	0.283
D29 Benign neoplasm of male genital organs	0.716	0.283
D28 Benign neoplasm of other and unspecified female genital organs	0.716	0.283
D26 Other benign neoplasms of uterus	0.716	0.283
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.716	0.283
D19 Benign neoplasm of mesothelial tissue	0.716	0.283
D16 Benign neoplasm of bone and articular cartilage	0.716	0.283
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.716	0.283
D14 Benign neoplasm of middle ear and respiratory system	0.716	0.283
D10 Benign neoplasm of mouth and pharynx	0.716	0.283
D34 Benign neoplasm of thyroid gland	0.716	0.283
T79-T79 Certain early complications of trauma	0.716	0.283
I44.1 Atrioventricular block, second degree	0.717	0.283
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.714	0.285
G35 Multiple sclerosis	0.714	0.285
D22.3 Melanocytic naevi of other and unspecified parts of face	0.714	0.286
I67.1 Cerebral aneurysm, nonruptured	0.714	0.286
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.713	0.287
D12.9 Anus and anal canal	0.713	0.287
D12.7 Rectosigmoid junction	0.713	0.287
D12.1 Appendix	0.713	0.287
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.713	0.287
T66-T78 Other and unspecified effects of external causes	0.713	0.287
O72 Postpartum haemorrhage	0.710	0.290
O20-O29 Other maternal disorders predominantly related to pregnancy	0.710	0.290
K56.7 Ileus, unspecified	0.709	0.291
K56.3 Gallstone ileus	0.709	0.291
K56.1 Intussusception	0.709	0.291
K56.0 Paralytic ileus	0.709	0.291
S20-S29 Injuries to the thorax	0.708	0.292
V20-V29 Motorcycle rider injured in transport accident	0.708	0.292
K56.5 Intestinal adhesions [bands] with obstruction	0.707	0.293
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.707	0.293
O63.1 Prolonged second stage (of labour)	0.707	0.293
Z03.5 Observation for other suspected cardiovascular diseases	0.707	0.293
D37-D48 Neoplasms of uncertain or unknown behaviour	0.707	0.293
W20-W49 Exposure to inanimate mechanical forces	0.706	0.294
H40 Glaucoma	0.705	0.295
K35-K38 Diseases of appendix	0.704	0.296
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.701	0.299
K70 Alcoholic liver disease	0.701	0.299
K63.4 Enteroptosis	0.700	0.300
K63.0 Abscess of intestine	0.700	0.300
S40-S49 Injuries to the shoulder and upper arm	0.700	0.300
K83.9 Disease of biliary tract, unspecified	0.700	0.300
K83.5 Biliary cyst	0.700	0.300
K83.4 Spasm of sphincter of Oddi	0.700	0.300
K83.3 Fistula of bile duct	0.700	0.300
K83.2 Perforation of bile duct	0.700	0.300
K72 Hepatic failure, not elsewhere classified	0.698	0.302
I64 Stroke, not specified as haemorrhage or infarction	0.698	0.302
H33.0 Retinal detachment with retinal break	0.698	0.302
S71 Open wound of hip and thigh	0.696	0.303
T33-T35 Frostbite	0.696	0.304
T26-T28 Burns and corrosions confined to eye and internal organs	0.696	0.304
T20-T25 Burns and corrosions of external body surface, specified by site	0.696	0.304
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.696	0.304
T00-T07 Injuries involving multiple body regions	0.696	0.304
S10-S19 Injuries to the neck	0.696	0.304
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.696	0.304
I00-I02 Acute rheumatic fever	0.695	0.305
C32 Malignant neoplasm of larynx	0.694	0.306
L50-L54 Urticaria and erythema	0.693	0.307
N30.1 Interstitial cystitis (chronic)	0.693	0.307
N28.1 Cyst of kidney, acquired	0.693	0.307
K82 Other diseases of gallbladder	0.692	0.308
Z40-Z54 Persons encountering health services for specific procedures and health care	0.690	0.310
S72 Fracture of femur	0.690	0.310
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.690	0.310
D27 Benign neoplasm of ovary	0.690	0.310
C79 Secondary malignant neoplasm of other sites	0.689	0.311
K55.2 Angiodysplasia of colon	0.689	0.311
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.688	0.311
Y35-Y36 Legal intervention and operations of war	0.688	0.311
Y10-Y34 Event of undetermined intent	0.688	0.311
Y00-Y09 Assault	0.688	0.311
X85-X99 Assault	0.688	0.311
X60-X84 Intentional self-harm	0.688	0.311
X58-X59 Accidental exposure to other and unspecified factors	0.688	0.311
X50-X57 Overexertion, travel and privation	0.688	0.311
X40-X49 Accidental poisoning by and exposure to noxious substances	0.688	0.311
X30-X39 Exposure to forces of nature	0.688	0.311
X20-X29 Contact with venomous animals and plants	0.688	0.311
X10-X19 Contact with heat and hot substances	0.688	0.311
X00-X09 Exposure to smoke, fire and flames	0.688	0.311
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.688	0.311
W75-W84 Other accidental threats to breathing	0.688	0.311
W65-W74 Accidental drowning and submersion	0.688	0.311
W50-W64 Exposure to animate mechanical forces	0.688	0.311
V98-V99 Other and unspecified transport accidents	0.688	0.311
V95-V97 Air and space transport accidents	0.688	0.311
V90-V94 Water transport accidents	0.688	0.311
V80-V89 Other land transport accidents	0.688	0.311
V70-V79 Bus occupant injured in transport accident	0.688	0.311
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.688	0.311
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.688	0.311
V40-V49 Car occupant injured in transport accident	0.688	0.311
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.688	0.311
V01-V09 Pedestrian injured in transport accident	0.688	0.311
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.688	0.312
N18.9 Chronic renal failure, unspecified	0.688	0.312
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.688	0.312
T90 Sequelae of injuries of head	0.688	0.312
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.687	0.312
D22.5 Melanocytic naevi of trunk	0.687	0.313
Y84.8 Other medical procedures	0.687	0.313
D11 Benign neoplasm of major salivary glands	0.686	0.314
D12.6 Colon, unspecified	0.685	0.315
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.685	0.315
K80.3 Calculus of bile duct with cholangitis	0.684	0.316
O34 Maternal care for known or suspected abnormality of pelvic organs	0.682	0.318
K80.4 Calculus of bile duct with cholecystitis	0.681	0.319
I34 Nonrheumatic mitral valve disorders	0.681	0.319
I68 Cerebrovascular disorders in diseases classified elsewhere	0.680	0.320
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.680	0.320
I62 Other nontraumatic intracranial haemorrhage	0.680	0.320
H20 Iridocyclitis	0.680	0.320
I71.3 Abdominal aortic aneurysm, ruptured	0.679	0.321
I46 Cardiac arrest	0.679	0.321
I77.1 Stricture of artery	0.679	0.321
N19 Unspecified renal failure	0.678	0.322
Z04.8 Examination and observation for other specified reasons	0.677	0.322
N00-N08 Glomerular diseases	0.676	0.323
N13 Obstructive and reflux uropathy	0.676	0.324
N28.9 Disorder of kidney and ureter, unspecified	0.676	0.324
A08 Viral and other specified intestinal infections	0.675	0.325
T92 Sequelae of injuries of upper limb	0.675	0.325
D17 Benign lipomatous neoplasm	0.675	0.325
Chapter VIII Diseases of the ear and mastoid process	0.674	0.326
H46-H48 Disorders of optic nerve and visual pathways	0.672	0.328
H10-H13 Disorders of conjunctiva	0.672	0.328
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.672	0.328
K52 Other non-infective gastro-enteritis and colitis	0.671	0.329
I47.1 Supraventricular tachycardia	0.671	0.329
D70-D77 Other diseases of blood and blood-forming organs	0.670	0.330
D35 Benign neoplasm of other and unspecified endocrine glands	0.667	0.333
S61 Open wound of wrist and hand	0.667	0.333
N17.9 Acute renal failure, unspecified	0.666	0.334
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.666	0.334
T93 Sequelae of injuries of lower limb	0.665	0.334
O85-O92 Complications predominantly related to the puerperium	0.664	0.336
L10-L14 Bullous disorders	0.663	0.337
K66.9 Disorder of peritoneum, unspecified	0.663	0.337
K66.8 Other specified disorders of peritoneum	0.663	0.337
K66.1 Haemoperitoneum	0.663	0.337
H43 Disorders of vitreous body	0.663	0.337
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.658	0.342
K90-K93 Other diseases of the digestive system	0.658	0.342
L85 Other epidermal thickening	0.658	0.342
K55.0 Acute vascular disorders of intestine	0.654	0.346
I98 Other disorders of circulatory system in diseases classified elsewhere	0.654	0.346
D23.4 Skin of scalp and neck	0.653	0.347
N30.9 Cystitis, unspecified	0.651	0.349
O46 Antepartum haemorrhage, not elsewhere classified	0.650	0.350
S60 Superficial injury of wrist and hand	0.650	0.350
G80-G83 Cerebral palsy and other paralytic syndromes	0.649	0.351
S62 Fracture at wrist and hand level	0.649	0.351
I45 Other conduction disorders	0.648	0.352
N18.2 Chronic kidney disease, stage 2	0.648	0.352
I77.9 Disorder of arteries and arterioles, unspecified	0.648	0.352
G90-G99 Other disorders of the nervous system	0.647	0.353
I78 Diseases of capillaries	0.647	0.353
D23.9 Skin, unspecified	0.647	0.353
D23.2 Skin of ear and external auricular canal	0.647	0.353
D23.0 Skin of lip	0.647	0.353
G40-G47 Episodic and paroxysmal disorders	0.647	0.353
D22.9 Melanocytic naevi, unspecified	0.647	0.353
D22.2 Melanocytic naevi of ear and external auricular canal	0.647	0.353
D22.1 Melanocytic naevi of eyelid, including canthus	0.647	0.353
D22.0 Melanocytic naevi of lip	0.647	0.353
N70-N77 Inflammatory diseases of female pelvic organs	0.647	0.353
L91 Hypertrophic disorders of skin	0.646	0.354
Y60-Y69 Misadventures to patients during surgical and medical care	0.645	0.355
C77.0 Lymph nodes of head, face and neck	0.645	0.355
H33.3 Retinal breaks without detachment	0.643	0.357
K77 Liver disorders in diseases classified elsewhere	0.643	0.357
K75 Other inflammatory liver diseases	0.643	0.357
K73 Chronic hepatitis, not elsewhere classified	0.643	0.357
K71 Toxic liver disease	0.643	0.357
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.642	0.358
I52 Other heart disorders in diseases classified elsewhere	0.641	0.359
I48 Atrial fibrillation and flutter	0.641	0.359
I43 Cardiomyopathy in diseases classified elsewhere	0.641	0.359
I41 Myocarditis in diseases classified elsewhere	0.641	0.359
I40 Acute myocarditis	0.641	0.359
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.641	0.359
I37 Pulmonary valve disorders	0.641	0.359
I36 Nonrheumatic tricuspid valve disorders	0.641	0.359
I33 Acute and subacute endocarditis	0.641	0.359
I32 Pericarditis in diseases classified elsewhere	0.641	0.359
I30 Acute pericarditis	0.641	0.359
I38 Endocarditis, valve unspecified	0.641	0.359
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.639	0.360
I72 Other aneurysm	0.639	0.360
I70 Atherosclerosis	0.639	0.360
Z22.3 Carrier of other specified bacterial diseases	0.639	0.361
N18.3 Chronic kidney disease, stage 3	0.638	0.362
C76 Malignant neoplasm of other and ill-defined sites	0.638	0.362
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.638	0.362
L95 Vasculitis limited to skin, not elsewhere classified	0.638	0.362
L94 Other localised connective tissue disorders	0.638	0.362
L93 Lupus erythematosus	0.638	0.362
L87 Transepidermal elimination disorders	0.638	0.362
L88 Pyoderma gangrenosum	0.638	0.362
L86 Keratoderma in diseases classified elsewhere	0.638	0.362
L84 Corns and callosities	0.638	0.362
L83 Acanthosis nigricans	0.638	0.362
L80 Vitiligo	0.638	0.362
A09.9 Gastroenteritis and colitis of unspecified origin	0.638	0.362
D22.6 Melanocytic naevi of upper limb, including shoulder	0.637	0.363
C77.5 Intrapelvic lymph nodes	0.636	0.364
Z12.1 Special screening examination for neoplasm of intestinal tract	0.636	0.364
I74 Arterial embolism and thrombosis	0.636	0.364
N60 Benign mammary dysplasia	0.635	0.365
N62 Hypertrophy of breast	0.635	0.365
Z29 Need for other prophylactic measures	0.635	0.365
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.634	0.366
N27 Small kidney of unknown cause	0.634	0.366
N25 Disorders resulting from impaired renal tubular function	0.634	0.366
N26 Unspecified contracted kidney	0.634	0.366
O80-O84 Delivery	0.634	0.366
K60 Fissure and fistula of anal and rectal regions	0.634	0.366
L90 Atrophic disorders of skin	0.632	0.368
I31 Other diseases of pericardium	0.631	0.369
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.631	0.369
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.630	0.369
K81 Cholecystitis	0.629	0.371
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.628	0.371
C56 Malignant neoplasm of ovary	0.628	0.372
K86.9 Disease of pancreas, unspecified	0.628	0.372
S00-S09 Injuries to the head	0.628	0.372
D60-D64 Aplastic and other anaemias	0.627	0.372
K86.1 Other chronic pancreatitis	0.627	0.373
D32.9 Meninges, unspecified	0.627	0.373
O47 False labour	0.627	0.373
L40.9 Psoriasis, unspecified	0.626	0.374
I67.7 Cerebral arteritis, not elsewhere classified	0.625	0.375
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.625	0.375
I67.5 Moyamoya disease	0.625	0.375
I67.4 Hypertensive encephalopathy	0.625	0.375
I67.3 Progressive vascular leukoencephalopathy	0.625	0.375
I67.2 Cerebral atherosclerosis	0.625	0.375
I67.0 Dissection of cerebral arteries, nonruptured	0.625	0.375
H33.5 Other retinal detachments	0.625	0.375
K40-K46 Hernia	0.625	0.375
O94-O99 Other obstetric conditions, not elsewhere classified	0.624	0.376
H35 Other retinal disorders	0.624	0.376
Z11 Special screening examination for infectious and parasitic diseases	0.623	0.377
Z10 Routine general health check-up of defined subpopulation	0.623	0.377
F40-F48 Neurotic, stress-related and somatoform disorders	0.623	0.377
L89.1 Stage II decubitus ulcer	0.620	0.380
Y84.2 Radiological procedure and radiotherapy	0.619	0.381
H40.0 Glaucoma suspect	0.619	0.381
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.619	0.381
C38 Malignant neoplasm of heart, mediastinum and pleura	0.619	0.381
C31 Malignant neoplasm of accessory sinuses	0.619	0.381
C30 Malignant neoplasm of nasal cavity and middle ear	0.619	0.381
C37 Malignant neoplasm of thymus	0.619	0.381
C33 Malignant neoplasm of trachea	0.619	0.381
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.618	0.382
D12.4 Descending colon	0.618	0.382
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.618	0.382
H52 Disorders of refraction and accommodation	0.618	0.382
I63.8 Other cerebral infarction	0.618	0.382
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.618	0.382
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.618	0.382
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.618	0.382
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.618	0.382
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.618	0.382
L81.4 Other melanin hyperpigmentation	0.618	0.382
C77.4 Inguinal and lower limb lymph nodes	0.616	0.384
A08.4 Viral intestinal infection, unspecified	0.615	0.385
N63 Unspecified lump in breast	0.615	0.385
N64.9 Disorder of breast, unspecified	0.615	0.385
C80.0 Malignant neoplasm, primary site unknown, so stated	0.614	0.386
I44.2 Atrioventricular block, complete	0.613	0.387
N18.5 Chronic kidney disease, stage 5	0.613	0.387
I60.8 Other subarachnoid haemorrhage	0.613	0.387
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.613	0.387
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.613	0.387
I60.5 Subarachnoid haemorrhage from vertebral artery	0.613	0.387
I60.4 Subarachnoid haemorrhage from basilar artery	0.613	0.387
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.613	0.387
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.613	0.387
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.613	0.387
K76.6 Portal hypertension	0.613	0.387
O68 Labour and delivery complicated by foetal stress [distress]	0.612	0.388
D23.7 Skin of lower limb, including hip	0.610	0.390
G30-G32 Other degenerative diseases of the nervous system	0.610	0.390
T17 Foreign body in respiratory tract	0.610	0.390
I05-I09 Chronic rheumatic heart diseases	0.609	0.390
G70-G73 Diseases of myoneural junction and muscle	0.609	0.390
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.609	0.390
G00-G09 Inflammatory diseases of the central nervous system	0.609	0.390
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.609	0.391
I44.6 Other and unspecified fascicular block	0.608	0.392
I44.5 Left posterior fascicular block	0.608	0.392
I44.4 Left anterior fascicular block	0.608	0.392
I44.3 Other and unspecified atrioventricular block	0.608	0.392
T98 Sequelae of other and unspecified effects of external causes	0.608	0.392
T95 Sequelae of burns, corrosions and frostbite	0.608	0.392
T94 Sequelae of injuries involving multiple and unspecified body regions	0.608	0.392
T91 Sequelae of injuries of neck and trunk	0.608	0.392
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.608	0.392
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.608	0.392
H32 Chorioretinal disorders in diseases classified elsewhere	0.608	0.392
H31 Other disorders of choroid	0.608	0.392
H30 Chorioretinal inflammation	0.608	0.392
N18.0 End-stage renal disease	0.607	0.393
V18 Pedal cyclist injured in noncollision transport accident	0.606	0.394
H33.2 Serous retinal detachment	0.605	0.395
C92 Myeloid leukaemia	0.605	0.395
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.605	0.395
D36.1 Peripheral nerves and autonomic nervous system	0.604	0.396
T36-T50 Poisoning by drugs, medicaments and biological substances	0.604	0.396
K62 Other diseases of anus and rectum	0.604	0.396
S79 Other and unspecified injuries of hip and thigh	0.603	0.396
S78 Traumatic amputation of hip and thigh	0.603	0.396
S77 Crushing injury of hip and thigh	0.603	0.396

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations