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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs181867028
log Bayes Factor = 0.380125
Chromosome 2   position 2,545,734  (GRCh37) Explore rs181867028 on Ensembl!
Variant rs181867028 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.578 0.422 0.000
Chapter VII Diseases of the eye and adnexa
0.542 0.458 0.000
Chapter XIV Diseases of the genitourinary system
0.538 0.462 0.000
Chapter IX Diseases of the circulatory system
0.534 0.466 0.000
Chapter XXI Factors influencing health status and contact with health services
0.511 0.489 0.000
H25-H28 Disorders of lens
0.499 0.501 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.499 0.501 0.000
Chapter II Neoplasms
0.495 0.505 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.493 0.507 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.490 0.510 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.488 0.512 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.478 0.522 0.000
Chapter VI Diseases of the nervous system
0.476 0.524 0.000
I30-I52 Other forms of heart disease
0.473 0.527 0.000
I60-I69 Cerebrovascular diseases
0.471 0.529 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.467 0.533 0.000
H26 Other cataract
0.464 0.536 0.000
N30-N39 Other diseases of urinary system
0.464 0.536 0.000
R11 Nausea and vomiting
0.459 0.541 0.000
N17-N19 Renal failure
0.456 0.543 0.000
Chapter X Diseases of the respiratory system
0.450 0.550 0.000
Chapter XX External causes of morbidity and mortality
0.445 0.554 0.000
Chapter I Certain infectious and parasitic diseases
0.440 0.560 0.000
D10-D36 Benign neoplasms
0.439 0.561 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.439 0.561 0.000
H26.9 Cataract, unspecified
0.439 0.561 0.000
E70-E90 Metabolic disorders
0.436 0.564 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.435 0.565 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.431 0.569 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.431 0.569 0.000
N84 Polyp of female genital tract
0.427 0.573 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.422 0.578 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.421 0.579 0.000
H30-H36 Disorders of choroid and retina
0.420 0.580 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.420 0.580 0.000
Chapter XXII Codes for special purposes
0.415 0.585 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.415 0.585 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.415 0.585 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.415 0.585 0.000
Chapter VIII Diseases of the ear and mastoid process
0.415 0.585 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.413 0.587 0.000
I20-I25 Ischaemic heart diseases
0.412 0.588 0.000
N39 Other disorders of urinary system
0.393 0.607 0.000
N89 Other noninflammatory disorders of vagina
0.392 0.608 0.000
N92 Excessive, frequent and irregular menstruation
0.390 0.609 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.390 0.610 0.000
H55-H59 Other disorders of eye and adnexa
0.389 0.611 0.000
H53-H54 Visual disturbances and blindness
0.389 0.611 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.389 0.611 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.389 0.611 0.000
H43-H45 Disorders of vitreous body and globe
0.389 0.611 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.389 0.611 0.000
H10-H13 Disorders of conjunctiva
0.389 0.611 0.000
C15-C26 Malignant neoplasms of digestive organs
0.388 0.611 0.000
I69 Sequelae of cerebrovascular disease
0.388 0.611 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.387 0.613 0.000
Z37 Outcome of delivery
0.387 0.613 0.000
G40-G47 Episodic and paroxysmal disorders
0.386 0.614 0.000
N99-N99 Other disorders of the genitourinary system
0.386 0.614 0.000
N60-N64 Disorders of breast
0.386 0.614 0.000
N25-N29 Other disorders of kidney and ureter
0.386 0.614 0.000
N10-N16 Renal tubulo-interstitial diseases
0.386 0.614 0.000
N00-N08 Glomerular diseases
0.386 0.614 0.000
I50 Heart failure
0.386 0.614 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.383 0.616 0.000
I05-I09 Chronic rheumatic heart diseases
0.383 0.617 0.000
I00-I02 Acute rheumatic fever
0.383 0.617 0.000
C51-C58 Malignant neoplasms of female genital organs
0.382 0.618 0.000
N84.0 Polyp of corpus uteri
0.382 0.618 0.000
N17 Acute renal failure
0.379 0.621 0.000
N95 Menopausal and other perimenopausal disorders
0.378 0.622 0.000
I63 Cerebral infarction
0.378 0.622 0.000
H25 Senile cataract
0.377 0.623 0.000
N32 Other disorders of bladder
0.377 0.623 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.377 0.623 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.376 0.624 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.375 0.625 0.000
H40-H42 Glaucoma
0.374 0.626 0.000
R15 Faecal incontinence
0.374 0.626 0.000
J30-J39 Other diseases of upper respiratory tract
0.374 0.626 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.373 0.626 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.373 0.627 0.000
S50-S59 Injuries to the elbow and forearm
0.373 0.627 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.372 0.628 0.000
G90-G99 Other disorders of the nervous system
0.372 0.628 0.000
I34 Nonrheumatic mitral valve disorders
0.371 0.629 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.371 0.629 0.000
R18 Ascites
0.371 0.629 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.371 0.629 0.000
N20-N23 Urolithiasis
0.368 0.631 0.000
S80-S89 Injuries to the knee and lower leg
0.368 0.632 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.367 0.633 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.367 0.633 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.366 0.633 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.364 0.636 0.000
E10-E14 Diabetes mellitus
0.364 0.636 0.000
D23 Other benign neoplasms of skin
0.364 0.636 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.362 0.638 0.000
J09-J18 Influenza and pneumonia
0.362 0.638 0.000
I45 Other conduction disorders
0.360 0.640 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.359 0.640 0.000
N18 Chronic renal failure
0.359 0.641 0.000
I51 Complications and ill-defined descriptions of heart disease
0.358 0.642 0.000
H02 Other disorders of eyelid
0.358 0.642 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.358 0.642 0.000
H27 Other disorders of lens
0.358 0.642 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.358 0.642 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.358 0.642 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.358 0.642 0.000
R47-R49 Symptoms and signs involving speech and voice
0.358 0.642 0.000
I95 Hypotension
0.357 0.643 0.000
I26 Pulmonary embolism
0.357 0.643 0.000
L60-L75 Disorders of skin appendages
0.356 0.644 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.355 0.645 0.000
D00-D09 In situ neoplasms
0.355 0.645 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.355 0.645 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.355 0.645 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.355 0.645 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.355 0.645 0.000
C64-C68 Malignant neoplasms of urinary tract
0.355 0.645 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.355 0.645 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.355 0.645 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.355 0.645 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.355 0.645 0.000
R14 Flatulence and related conditions
0.355 0.645 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.353 0.646 0.000
T79-T79 Certain early complications of trauma
0.353 0.646 0.000
T66-T78 Other and unspecified effects of external causes
0.353 0.646 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.353 0.646 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.353 0.646 0.000
T33-T35 Frostbite
0.353 0.646 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.353 0.646 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.353 0.646 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.353 0.646 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.353 0.646 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.353 0.646 0.000
T00-T07 Injuries involving multiple body regions
0.353 0.646 0.000
S90-S99 Injuries to the ankle and foot
0.353 0.646 0.000
S70-S79 Injuries to the hip and thigh
0.353 0.646 0.000
S60-S69 Injuries to the wrist and hand
0.353 0.646 0.000
S40-S49 Injuries to the shoulder and upper arm
0.353 0.646 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.353 0.646 0.000
S20-S29 Injuries to the thorax
0.353 0.646 0.000
S10-S19 Injuries to the neck
0.353 0.646 0.000
S00-S09 Injuries to the head
0.353 0.646 0.000
I44 Atrioventricular and left bundle-branch block
0.353 0.647 0.000
C50-C50 Malignant neoplasm of breast
0.352 0.648 0.000
Z50 Care involving use of rehabilitation procedures
0.352 0.648 0.000
N98 Complications associated with artificial fertilisation
0.351 0.649 0.000
N97 Female infertility
0.351 0.649 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.351 0.649 0.000
N93 Other abnormal uterine and vaginal bleeding
0.351 0.649 0.000
N91 Absent, scanty and rare menstruation
0.351 0.649 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.351 0.649 0.000
N88 Other noninflammatory disorders of cervix uteri
0.351 0.649 0.000
N87 Dysplasia of cervix uteri
0.351 0.649 0.000
N82 Fistulae involving female genital tract
0.351 0.649 0.000
N80 Endometriosis
0.351 0.649 0.000
N96 Habitual aborter
0.351 0.649 0.000
N86 Erosion and ectropion of cervix uteri
0.351 0.649 0.000
E50-E64 Other nutritional deficiencies
0.350 0.650 0.000
E40-E46 Malnutrition
0.350 0.650 0.000
E20-E35 Disorders of other endocrine glands
0.350 0.650 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.350 0.650 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.350 0.650 0.000
Z37.0 Single live birth
0.349 0.650 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.349 0.651 0.000
E86 Volume depletion
0.349 0.651 0.000
E78.5 Hyperlipidaemia, unspecified
0.347 0.653 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.345 0.654 0.000
N39.0 Urinary tract infection, site not specified
0.345 0.654 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.345 0.655 0.000
R13 Dysphagia
0.345 0.655 0.000
Chapter V Mental and behavioural disorders
0.344 0.655 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.344 0.656 0.000
D17 Benign lipomatous neoplasm
0.344 0.656 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.343 0.657 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.343 0.657 0.000
R17 Unspecified jaundice
0.343 0.657 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.343 0.657 0.000
G70-G73 Diseases of myoneural junction and muscle
0.341 0.659 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.341 0.659 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.341 0.659 0.000
G30-G32 Other degenerative diseases of the nervous system
0.341 0.659 0.000
G20-G26 Extrapyramidal and movement disorders
0.341 0.659 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.341 0.659 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.341 0.659 0.000
B95-B98 Bacterial, viral and other infectious agents
0.341 0.659 0.000
I52 Other heart disorders in diseases classified elsewhere
0.339 0.660 0.000
I49 Other cardiac arrhythmias
0.339 0.660 0.000
I48 Atrial fibrillation and flutter
0.339 0.660 0.000
I47 Paroxysmal tachycardia
0.339 0.660 0.000
I46 Cardiac arrest
0.339 0.660 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.339 0.660 0.000
I42 Cardiomyopathy
0.339 0.660 0.000
I41 Myocarditis in diseases classified elsewhere
0.339 0.660 0.000
I40 Acute myocarditis
0.339 0.660 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.339 0.660 0.000
I37 Pulmonary valve disorders
0.339 0.660 0.000
I36 Nonrheumatic tricuspid valve disorders
0.339 0.660 0.000
I35 Nonrheumatic aortic valve disorders
0.339 0.660 0.000
I33 Acute and subacute endocarditis
0.339 0.660 0.000
I32 Pericarditis in diseases classified elsewhere
0.339 0.660 0.000
I31 Other diseases of pericardium
0.339 0.660 0.000
I30 Acute pericarditis
0.339 0.660 0.000
I38 Endocarditis, valve unspecified
0.339 0.660 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.339 0.661 0.000
R12 Heartburn
0.339 0.661 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.338 0.662 0.000
I67 Other cerebrovascular diseases
0.338 0.662 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.338 0.662 0.000
I62 Other nontraumatic intracranial haemorrhage
0.338 0.662 0.000
I61 Intracerebral haemorrhage
0.338 0.662 0.000
I60 Subarachnoid haemorrhage
0.338 0.662 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.338 0.662 0.000
I21 Acute myocardial infarction
0.336 0.664 0.000
E65-E68 Obesity and other hyperalimentation
0.336 0.664 0.000
L50-L54 Urticaria and erythema
0.335 0.665 0.000
L40-L45 Papulosquamous disorders
0.335 0.665 0.000
L20-L30 Dermatitis and eczema
0.335 0.665 0.000
L10-L14 Bullous disorders
0.335 0.665 0.000
H33 Retinal detachments and breaks
0.333 0.667 0.000
H26.8 Other specified cataract
0.333 0.667 0.000
H26.4 After-cataract
0.333 0.667 0.000
H26.3 Drug-induced cataract
0.333 0.667 0.000
H26.2 Complicated cataract
0.333 0.667 0.000
H26.1 Traumatic cataract
0.333 0.667 0.000
H26.0 Infantile, juvenile and presenile cataract
0.333 0.667 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.333 0.667 0.000
N37 Urethral disorders in diseases classified elsewhere
0.332 0.667 0.000
N36 Other disorders of urethra
0.332 0.667 0.000
N34 Urethritis and urethral syndrome
0.332 0.667 0.000
N33 Bladder disorders in diseases classified elsewhere
0.332 0.667 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.332 0.667 0.000
N30 Cystitis
0.332 0.667 0.000
R50-R69 General symptoms and signs
0.330 0.670 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.330 0.670 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.329 0.671 0.000
J90-J94 Other diseases of pleura
0.329 0.671 0.000
Z87 Personal history of other diseases and conditions
0.328 0.672 0.000
N19 Unspecified renal failure
0.327 0.672 0.000
R10 Abdominal and pelvic pain
0.327 0.673 0.000
W00-W19 Falls
0.325 0.675 0.000
N17.9 Acute renal failure, unspecified
0.323 0.677 0.000
J95-J99 Other diseases of the respiratory system
0.323 0.677 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.323 0.677 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.323 0.677 0.000
J60-J70 Lung diseases due to external agents
0.323 0.677 0.000
J00-J06 Acute upper respiratory infections
0.323 0.677 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.322 0.678 0.000
D22 Melanocytic naevi
0.322 0.678 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.321 0.679 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.320 0.679 0.000
A00-A09 Intestinal infectious diseases
0.320 0.680 0.000
D25 Leiomyoma of uterus
0.320 0.680 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.319 0.680 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.319 0.680 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.319 0.680 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.319 0.680 0.000
Y35-Y36 Legal intervention and operations of war
0.319 0.680 0.000
Y10-Y34 Event of undetermined intent
0.319 0.680 0.000
Y00-Y09 Assault
0.319 0.680 0.000
X85-X99 Assault
0.319 0.680 0.000
X60-X84 Intentional self-harm
0.319 0.680 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.319 0.680 0.000
X50-X57 Overexertion, travel and privation
0.319 0.680 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.319 0.680 0.000
X30-X39 Exposure to forces of nature
0.319 0.680 0.000
X20-X29 Contact with venomous animals and plants
0.319 0.680 0.000
X10-X19 Contact with heat and hot substances
0.319 0.680 0.000
X00-X09 Exposure to smoke, fire and flames
0.319 0.680 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.319 0.680 0.000
W75-W84 Other accidental threats to breathing
0.319 0.680 0.000
W65-W74 Accidental drowning and submersion
0.319 0.680 0.000
W50-W64 Exposure to animate mechanical forces
0.319 0.680 0.000
W20-W49 Exposure to inanimate mechanical forces
0.319 0.680 0.000
V98-V99 Other and unspecified transport accidents
0.319 0.680 0.000
V95-V97 Air and space transport accidents
0.319 0.680 0.000
V90-V94 Water transport accidents
0.319 0.680 0.000
V80-V89 Other land transport accidents
0.319 0.680 0.000
V70-V79 Bus occupant injured in transport accident
0.319 0.680 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.319 0.680 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.319 0.680 0.000
V40-V49 Car occupant injured in transport accident
0.319 0.680 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.319 0.680 0.000
V20-V29 Motorcycle rider injured in transport accident
0.319 0.680 0.000
V10-V19 Pedal cyclist injured in transport accident
0.319 0.680 0.000
V01-V09 Pedestrian injured in transport accident
0.319 0.680 0.000
R41.0 Disorientation, unspecified
0.319 0.681 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.318 0.682 0.000
M45-M49 Spondylopathies
0.316 0.684 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.316 0.684 0.000
B99-B99 Other infectious diseases
0.315 0.684 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.315 0.684 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.315 0.684 0.000
B65-B83 Helminthiases
0.315 0.684 0.000
B50-B64 Protozoal diseases
0.315 0.684 0.000
B35-B49 Mycoses
0.315 0.684 0.000
B25-B34 Other viral diseases
0.315 0.684 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.315 0.684 0.000
B15-B19 Viral hepatitis
0.315 0.684 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.315 0.684 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.315 0.684 0.000
A80-A89 Viral infections of the central nervous system
0.315 0.684 0.000
A75-A79 Rickettsioses
0.315 0.684 0.000
A70-A74 Other diseases caused by chlamydiae
0.315 0.684 0.000
A65-A69 Other spirochaetal diseases
0.315 0.684 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.315 0.684 0.000
A20-A28 Certain zoonotic bacterial diseases
0.315 0.684 0.000
A15-A19 Tuberculosis
0.315 0.684 0.000
D36 Benign neoplasm of other and unspecified sites
0.315 0.685 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.315 0.685 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.315 0.685 0.000
D32 Benign neoplasm of meninges
0.315 0.685 0.000
D31 Benign neoplasm of eye and adnexa
0.315 0.685 0.000
D30 Benign neoplasm of urinary organs
0.315 0.685 0.000
D29 Benign neoplasm of male genital organs
0.315 0.685 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.315 0.685 0.000
D26 Other benign neoplasms of uterus
0.315 0.685 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.315 0.685 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.315 0.685 0.000
D19 Benign neoplasm of mesothelial tissue
0.315 0.685 0.000
D18 Haemangioma and lymphangioma, any site
0.315 0.685 0.000
D16 Benign neoplasm of bone and articular cartilage
0.315 0.685 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.315 0.685 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.315 0.685 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.315 0.685 0.000
D11 Benign neoplasm of major salivary glands
0.315 0.685 0.000
D10 Benign neoplasm of mouth and pharynx
0.315 0.685 0.000
D34 Benign neoplasm of thyroid gland
0.315 0.685 0.000
D27 Benign neoplasm of ovary
0.315 0.685 0.000
D24 Benign neoplasm of breast
0.315 0.685 0.000
Z30 Contraceptive management
0.315 0.685 0.000
Z39 Postpartum care and examination
0.315 0.685 0.000
Z38 Liveborn infants according to place of birth
0.315 0.685 0.000
Z36 Antenatal screening
0.315 0.685 0.000
Z35 Supervision of high-risk pregnancy
0.315 0.685 0.000
Z34 Supervision of normal pregnancy
0.315 0.685 0.000
Z32 Pregnancy examination and test
0.315 0.685 0.000
Z31 Procreative management
0.315 0.685 0.000
Z33 Pregnant state, incidental
0.315 0.685 0.000
I50.1 Left ventricular failure
0.315 0.685 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.314 0.686 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.314 0.686 0.000
Z50.1 Other physical therapy
0.313 0.687 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.313 0.687 0.000
E88 Other metabolic disorders
0.313 0.687 0.000
E85 Amyloidosis
0.313 0.687 0.000
E84 Cystic fibrosis
0.313 0.687 0.000
E83 Disorders of mineral metabolism
0.313 0.687 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.313 0.687 0.000
E79 Disorders of purine and pyrimidine metabolism
0.313 0.687 0.000
E77 Disorders of glycoprotein metabolism
0.313 0.687 0.000
E76 Disorders of glycosaminoglycan metabolism
0.313 0.687 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.313 0.687 0.000
E74 Other disorders of carbohydrate metabolism
0.313 0.687 0.000
E73 Lactose intolerance
0.313 0.687 0.000
E72 Other disorders of amino-acid metabolism
0.313 0.687 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.313 0.687 0.000
E70 Disorders of aromatic amino-acid metabolism
0.313 0.687 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.313 0.687 0.000
N35 Urethral stricture
0.313 0.687 0.000
C18 Malignant neoplasm of colon
0.312 0.688 0.000
L03 Cellulitis
0.312 0.688 0.000
Z88.5 Personal history of allergy to narcotic agent
0.312 0.688 0.000
R42 Dizziness and giddiness
0.312 0.688 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.312 0.688 0.000
H05 Disorders of orbit
0.312 0.688 0.000
H04 Disorders of lachrymal system
0.312 0.688 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.312 0.688 0.000
H01 Other inflammation of eyelid
0.312 0.688 0.000
H00 Hordeolum and chalazion
0.312 0.688 0.000
I63.9 Cerebral infarction, unspecified
0.311 0.689 0.000
J20-J22 Other acute lower respiratory infections
0.311 0.689 0.000
E00-E07 Disorders of thyroid gland
0.311 0.689 0.000
A30-A49 Other bacterial diseases
0.310 0.690 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.310 0.690 0.000
D23.1 Skin of eyelid, including canthus
0.310 0.690 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.309 0.691 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.309 0.691 0.000
I99 Other and unspecified disorders of circulatory system
0.309 0.691 0.000
I28 Other diseases of pulmonary vessels
0.309 0.691 0.000
I27 Other pulmonary heart diseases
0.309 0.691 0.000
Z92 Personal history of medical treatment
0.309 0.691 0.000
I25 Chronic ischaemic heart disease
0.309 0.691 0.000
J34 Other disorders of nose and nasal sinuses
0.306 0.694 0.000
G47 Sleep disorders
0.306 0.694 0.000
N84.9 Polyp of female genital tract, unspecified
0.306 0.694 0.000
N84.8 Polyp of other parts of female genital tract
0.306 0.694 0.000
N84.3 Polyp of vulva
0.306 0.694 0.000
N84.2 Polyp of vagina
0.306 0.694 0.000
N84.1 Polyp of cervix uteri
0.306 0.694 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.304 0.696 0.000
R46 Symptoms and signs involving appearance and behaviour
0.303 0.697 0.000
R45 Symptoms and signs involving emotional state
0.303 0.697 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.303 0.697 0.000
R43 Disturbances of smell and taste
0.303 0.697 0.000
R40 Somnolence, stupor and coma
0.303 0.697 0.000
N32.3 Diverticulum of bladder
0.302 0.697 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.302 0.697 0.000
D80-D89 Certain disorders involving the immune mechanism
0.302 0.698 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.302 0.698 0.000
D55-D59 Haemolytic anaemias
0.302 0.698 0.000
H36 Retinal disorders in diseases classified elsewhere
0.301 0.698 0.000
H35 Other retinal disorders
0.301 0.698 0.000
H34 Retinal vascular occlusions
0.301 0.698 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.301 0.698 0.000
H31 Other disorders of choroid
0.301 0.698 0.000
H30 Chorioretinal inflammation
0.301 0.698 0.000
C54 Malignant neoplasm of corpus uteri
0.301 0.698 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.301 0.699 0.000
Z98 Other postsurgical states
0.301 0.699 0.000
Z97 Presence of other devices
0.301 0.699 0.000
Z94 Transplanted organ and tissue status
0.301 0.699 0.000
Z93 Artificial opening status
0.301 0.699 0.000
Z89 Acquired absence of limb
0.301 0.699 0.000
Z84 Family history of other conditions
0.301 0.699 0.000
Z83 Family history of other specific disorders
0.301 0.699 0.000
Z81 Family history of mental and behavioural disorders
0.301 0.699 0.000
N85.0 Endometrial glandular hyperplasia
0.301 0.699 0.000
Z86 Personal history of certain other diseases
0.300 0.699 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.299 0.701 0.000
J18 Pneumonia, organism unspecified
0.299 0.701 0.000
N95.0 Postmenopausal bleeding
0.298 0.702 0.000
I34.0 Mitral (valve) insufficiency
0.298 0.702 0.000
H90-H95 Other disorders of ear
0.297 0.702 0.000
H80-H83 Diseases of inner ear
0.297 0.702 0.000
H65-H75 Diseases of middle ear and mastoid
0.297 0.702 0.000
H60-H62 Diseases of external ear
0.297 0.702 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.297 0.702 0.000
O85-O92 Complications predominantly related to the puerperium
0.297 0.702 0.000
O80-O84 Delivery
0.297 0.702 0.000
O60-O75 Complications of labour and delivery
0.297 0.702 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.297 0.702 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.297 0.702 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.297 0.702 0.000
O00-O08 Pregnancy with abortive outcome
0.297 0.702 0.000
P90-P96 Other disorders originating in the perinatal period
0.297 0.702 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.297 0.702 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.297 0.702 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.297 0.702 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.297 0.702 0.000
P35-P39 Infections specific to the perinatal period
0.297 0.702 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.297 0.702 0.000
P10-P15 Birth trauma
0.297 0.702 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.297 0.702 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.297 0.702 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.297 0.702 0.000
Q80-Q89 Other congenital malformations
0.297 0.702 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.297 0.702 0.000
Q60-Q64 Congenital malformations of the urinary system
0.297 0.702 0.000
Q50-Q56 Congenital malformations of genital organs
0.297 0.702 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.297 0.702 0.000
Q35-Q37 Cleft lip and cleft palate
0.297 0.702 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.297 0.702 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.297 0.702 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.297 0.702 0.000
Q00-Q07 Congenital malformations of the nervous system
0.297 0.702 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.297 0.702 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.297 0.702 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.297 0.703 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.296 0.703 0.000
T87 Complications peculiar to reattachment and amputation
0.296 0.703 0.000
T86 Failure and rejection of transplanted organs and tissues
0.296 0.703 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.296 0.703 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.296 0.703 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.296 0.703 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.296 0.703 0.000
I24 Other acute ischaemic heart diseases
0.295 0.705 0.000
I23 Certain current complications following acute myocardial infarction
0.295 0.705 0.000
I22 Subsequent myocardial infarction
0.295 0.705 0.000
I95.9 Hypotension, unspecified
0.294 0.706 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.293 0.707 0.000
N92.6 Irregular menstruation, unspecified
0.292 0.708 0.000
I65.2 Occlusion and stenosis of carotid artery
0.292 0.708 0.000
N81 Female genital prolapse
0.291 0.708 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.291 0.709 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.291 0.709 0.000
I50.0 Congestive heart failure
0.290 0.710 0.000
T81 Complications of procedures, not elsewhere classified
0.290 0.710 0.000
H25.8 Other senile cataract
0.290 0.710 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.290 0.710 0.000
D50-D53 Nutritional anaemias
0.289 0.711 0.000
G81 Hemiplegia
0.289 0.711 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.289 0.711 0.000
D60-D64 Aplastic and other anaemias
0.288 0.712 0.000
G43 Migraine
0.288 0.712 0.000
N18.9 Chronic renal failure, unspecified
0.288 0.712 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.288 0.712 0.000
N32.8 Other specified disorders of bladder
0.288 0.712 0.000
J33 Nasal polyp
0.287 0.712 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.287 0.713 0.000
S52 Fracture of forearm
0.287 0.713 0.000
Z42 Follow-up care involving plastic surgery
0.287 0.713 0.000
H02.4 Ptosis of eyelid
0.285 0.715 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.283 0.716 0.000
E10 Insulin-dependent diabetes mellitus
0.283 0.717 0.000
R51 Headache
0.283 0.717 0.000
R21 Rash and other nonspecific skin eruption
0.283 0.717 0.000
N39.9 Disorder of urinary system, unspecified
0.282 0.718 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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