TreeWAS – Variant ID: rs187296392

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.993	0.007
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.990	0.010
C34 Malignant neoplasm of bronchus and lung	0.990	0.010
D37-D48 Neoplasms of uncertain or unknown behaviour	0.977	0.023
T81 Complications of procedures, not elsewhere classified	0.976	0.024
Chapter XIV Diseases of the genitourinary system	0.971	0.029
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.970	0.030
Chapter VII Diseases of the eye and adnexa	0.970	0.030
C34.9 Bronchus or lung, unspecified	0.970	0.030
Chapter XX External causes of morbidity and mortality	0.967	0.033
Chapter I Certain infectious and parasitic diseases	0.967	0.033
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.966	0.034
A30-A49 Other bacterial diseases	0.960	0.040
A41 Other septicaemia	0.957	0.043
A41.9 Septicaemia, unspecified	0.950	0.050
M05-M14 Inflammatory polyarthropathies	0.947	0.053
H30-H36 Disorders of choroid and retina	0.940	0.060
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.936	0.064
M06 Other rheumatoid arthritis	0.916	0.084
Chapter VIII Diseases of the ear and mastoid process	0.916	0.084
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.914	0.086
Chapter V Mental and behavioural disorders	0.911	0.089
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.901	0.099
C34.1 Upper lobe, bronchus or lung	0.900	0.100
Chapter IV Endocrine, nutritional and metabolic diseases	0.896	0.104
N17-N19 Renal failure	0.895	0.105
C15-C26 Malignant neoplasms of digestive organs	0.894	0.106
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.893	0.107
T81.8 Other complications of procedures, not elsewhere classified	0.891	0.109
Chapter XXII Codes for special purposes	0.889	0.111
M06.9 Rheumatoid arthritis, unspecified	0.888	0.112
D70-D77 Other diseases of blood and blood-forming organs	0.881	0.119
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.879	0.121
T36-T50 Poisoning by drugs, medicaments and biological substances	0.879	0.121
S80-S89 Injuries to the knee and lower leg	0.870	0.130
H35 Other retinal disorders	0.870	0.130
T88 Other complications of surgical and medical care, not elsewhere classified	0.866	0.134
H53-H54 Visual disturbances and blindness	0.865	0.135
C34.3 Lower lobe, bronchus or lung	0.864	0.136
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.861	0.139
N80-N98 Noninflammatory disorders of female genital tract	0.861	0.139
E70-E90 Metabolic disorders	0.858	0.142
N95 Menopausal and other perimenopausal disorders	0.850	0.150
N17 Acute renal failure	0.846	0.154
Chapter IX Diseases of the circulatory system	0.842	0.158
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.841	0.159
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.840	0.160
M10 Gout	0.839	0.161
Y40 Systemic antibiotics	0.834	0.166
N70-N77 Inflammatory diseases of female pelvic organs	0.827	0.173
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.817	0.183
W20-W49 Exposure to inanimate mechanical forces	0.815	0.185
E83 Disorders of mineral metabolism	0.814	0.186
N10-N16 Renal tubulo-interstitial diseases	0.814	0.186
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.812	0.188
N17.9 Acute renal failure, unspecified	0.810	0.190
M70-M79 Other soft tissue disorders	0.809	0.191
N95.0 Postmenopausal bleeding	0.807	0.193
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.807	0.193
N90 Other noninflammatory disorders of vulva and perineum	0.805	0.195
H53 Visual disturbances	0.802	0.198
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.801	0.199
H33 Retinal detachments and breaks	0.801	0.199
S60-S69 Injuries to the wrist and hand	0.799	0.201
N60-N64 Disorders of breast	0.797	0.203
A41.2 Septicaemia due to unspecified staphylococcus	0.792	0.208
C51-C58 Malignant neoplasms of female genital organs	0.792	0.208
I20-I25 Ischaemic heart diseases	0.791	0.209
Q20-Q28 Congenital malformations of the circulatory system	0.790	0.209
H43-H45 Disorders of vitreous body and globe	0.787	0.213
T15-T19 Effects of foreign body entering through natural orifice	0.787	0.213
N00-N08 Glomerular diseases	0.786	0.213
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.785	0.215
H90-H95 Other disorders of ear	0.783	0.217
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.783	0.217
M15-M19 Arthrosis	0.781	0.219
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.781	0.219
H35.3 Degeneration of macula and posterior pole	0.781	0.219
I20 Angina pectoris	0.779	0.221
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.779	0.221
H35.8 Other specified retinal disorders	0.776	0.224
N95.2 Postmenopausal atrophic vaginitis	0.776	0.224
H65-H75 Diseases of middle ear and mastoid	0.774	0.226
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.774	0.226
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.773	0.227
D80-D89 Certain disorders involving the immune mechanism	0.771	0.229
N60 Benign mammary dysplasia	0.767	0.233
V80-V89 Other land transport accidents	0.766	0.234
F30-F39 Mood [affective] disorders	0.766	0.234
D70 Agranulocytosis	0.763	0.237
M10.9 Gout, unspecified	0.762	0.238
T81.9 Unspecified complication of procedure	0.760	0.240
N99-N99 Other disorders of the genitourinary system	0.759	0.241
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.759	0.241
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.758	0.242
S82 Fracture of lower leg, including ankle	0.756	0.243
I20.0 Unstable angina	0.756	0.244
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.755	0.245
C25 Malignant neoplasm of pancreas	0.755	0.245
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.753	0.247
H31 Other disorders of choroid	0.752	0.248
A41.0 Septicaemia due to Staphylococcus aureus	0.752	0.248
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.752	0.248
V40-V49 Car occupant injured in transport accident	0.751	0.249
M60-M63 Disorders of muscles	0.748	0.252
C20 Malignant neoplasm of rectum	0.746	0.254
A41.5 Septicaemia due to other Gram-negative organisms	0.746	0.254
D75 Other diseases of blood and blood-forming organs	0.745	0.255
S40-S49 Injuries to the shoulder and upper arm	0.745	0.255
C34.0 Main bronchus	0.740	0.260
M05 Seropositive rheumatoid arthritis	0.740	0.260
Y60-Y69 Misadventures to patients during surgical and medical care	0.739	0.261
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.738	0.262
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.737	0.263
N85 Other noninflammatory disorders of uterus, except cervix	0.737	0.263
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.737	0.263
D37.7 Other digestive organs	0.737	0.263
H55-H59 Other disorders of eye and adnexa	0.737	0.263
N90.5 Atrophy of vulva	0.735	0.265
B20-B24 Human immunodeficiency virus [HIV] disease	0.734	0.266
I95-I99 Other and unspecified disorders of the circulatory system	0.734	0.266
I20.9 Angina pectoris, unspecified	0.733	0.267
T84.1 Mechanical complication of internal fixation device of bones of limb	0.733	0.267
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.733	0.267
F00-F09 Organic, including symptomatic, mental disorders	0.732	0.267
F17 Mental and behavioural disorders due to use of tobacco	0.732	0.268
H53.1 Subjective visual disturbances	0.732	0.268
D46 Myelodysplastic syndromes	0.732	0.268
M19 Other arthrosis	0.732	0.268
D37.2 Small intestine	0.731	0.269
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.731	0.269
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.731	0.269
N25-N29 Other disorders of kidney and ureter	0.729	0.271
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.727	0.273
C97 Malignant neoplasms of independent (primary) multiple sites	0.727	0.273
T80 Complications following infusion, transfusion and therapeutic injection	0.726	0.273
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.726	0.274
S10-S19 Injuries to the neck	0.726	0.274
N19 Unspecified renal failure	0.726	0.274
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.726	0.274
Q80-Q89 Other congenital malformations	0.725	0.275
T84.3 Mechanical complication of other bone devices, implants and grafts	0.725	0.275
H46-H48 Disorders of optic nerve and visual pathways	0.725	0.275
S90-S99 Injuries to the ankle and foot	0.724	0.275
M91-M94 Chondropathies	0.724	0.276
Y43 Primarily systemic agents	0.723	0.277
Q50-Q56 Congenital malformations of genital organs	0.722	0.277
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.720	0.280
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.719	0.281
D73 Diseases of spleen	0.719	0.281
E88 Other metabolic disorders	0.718	0.282
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.717	0.283
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
D37.5 Rectum	0.717	0.283
M06.0 Seronegative rheumatoid arthritis	0.717	0.283
F80-F89 Disorders of psychological development	0.716	0.284
N84 Polyp of female genital tract	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
H90 Conductive and sensorineural hearing loss	0.716	0.284
T33-T35 Frostbite	0.715	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.284
T00-T07 Injuries involving multiple body regions	0.715	0.284
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.715	0.285
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.714	0.286
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.714	0.286
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.712	0.288
C38 Malignant neoplasm of heart, mediastinum and pleura	0.712	0.288
C32 Malignant neoplasm of larynx	0.712	0.288
C31 Malignant neoplasm of accessory sinuses	0.712	0.288
C30 Malignant neoplasm of nasal cavity and middle ear	0.712	0.288
C37 Malignant neoplasm of thymus	0.712	0.288
C33 Malignant neoplasm of trachea	0.712	0.288
A50-A64 Infections with a predominantly sexual mode of transmission	0.712	0.288
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.711	0.289
X60-X84 Intentional self-harm	0.711	0.289
E83.3 Disorders of phosphorus metabolism	0.711	0.289
T40.2 Other opioids	0.711	0.289
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.710	0.290
T87 Complications peculiar to reattachment and amputation	0.710	0.290
T86 Failure and rejection of transplanted organs and tissues	0.710	0.290
C34.8 Overlapping lesion of bronchus and lung	0.710	0.290
C34.2 Middle lobe, bronchus or lung	0.710	0.290
H10-H13 Disorders of conjunctiva	0.710	0.290
A46 Erysipelas	0.709	0.291
F17.1 Harmful use	0.709	0.291
M10.99 Gout, unspecified (Site unspecified)	0.708	0.292
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.708	0.292
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.708	0.292
T66-T78 Other and unspecified effects of external causes	0.707	0.293
H34 Retinal vascular occlusions	0.707	0.293
W22 Striking against or struck by other objects	0.705	0.295
X40-X49 Accidental poisoning by and exposure to noxious substances	0.705	0.295
M00-M03 Infectious arthropathies	0.703	0.297
M19.0 Primary arthrosis of other joints	0.703	0.297
C19 Malignant neoplasm of rectosigmoid junction	0.702	0.298
Y40.9 Systemic antibiotic, unspecified	0.702	0.298
D37.0 Lip, oral cavity and pharynx	0.702	0.298
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.701	0.299
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.701	0.299
V20-V29 Motorcycle rider injured in transport accident	0.701	0.299
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.700	0.300
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.700	0.300
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.700	0.300
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.700	0.300
D45 Polycythaemia vera	0.700	0.300
T81.7 Vascular complications following a procedure, not elsewhere classified	0.700	0.300
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.700	0.300
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.700	0.300
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.700	0.300
N73 Other female pelvic inflammatory diseases	0.699	0.301
M40-M43 Deforming dorsopathies	0.697	0.303
T79-T79 Certain early complications of trauma	0.697	0.303
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.696	0.304
Chapter XV Pregnancy, childbirth and the puerperium	0.696	0.304
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.696	0.304
S20-S29 Injuries to the thorax	0.696	0.304
Q23 Congenital malformations of aortic and mitral valves	0.696	0.304
H80-H83 Diseases of inner ear	0.695	0.305
N60.2 Fibroadenosis of breast	0.694	0.306
E87 Other disorders of fluid, electrolyte and acid-base balance	0.694	0.306
A41.8 Other specified septicaemia	0.693	0.306
Y35-Y36 Legal intervention and operations of war	0.693	0.307
Y10-Y34 Event of undetermined intent	0.693	0.307
Y00-Y09 Assault	0.693	0.307
X85-X99 Assault	0.693	0.307
X58-X59 Accidental exposure to other and unspecified factors	0.693	0.307
X50-X57 Overexertion, travel and privation	0.693	0.307
X30-X39 Exposure to forces of nature	0.693	0.307
X20-X29 Contact with venomous animals and plants	0.693	0.307
X10-X19 Contact with heat and hot substances	0.693	0.307
X00-X09 Exposure to smoke, fire and flames	0.693	0.307
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.693	0.307
W75-W84 Other accidental threats to breathing	0.693	0.307
W65-W74 Accidental drowning and submersion	0.693	0.307
W50-W64 Exposure to animate mechanical forces	0.693	0.307
V98-V99 Other and unspecified transport accidents	0.693	0.307
V95-V97 Air and space transport accidents	0.693	0.307
V90-V94 Water transport accidents	0.693	0.307
V70-V79 Bus occupant injured in transport accident	0.693	0.307
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.693	0.307
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.693	0.307
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.693	0.307
V01-V09 Pedestrian injured in transport accident	0.693	0.307
B99-B99 Other infectious diseases	0.693	0.307
B90-B94 Sequelae of infectious and parasitic diseases	0.693	0.307
B85-B89 Pediculosis, acariasis and other infestations	0.693	0.307
B65-B83 Helminthiases	0.693	0.307
B50-B64 Protozoal diseases	0.693	0.307
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.693	0.307
A80-A89 Viral infections of the central nervous system	0.693	0.307
A75-A79 Rickettsioses	0.693	0.307
A70-A74 Other diseases caused by chlamydiae	0.693	0.307
A65-A69 Other spirochaetal diseases	0.693	0.307
A20-A28 Certain zoonotic bacterial diseases	0.693	0.307
A15-A19 Tuberculosis	0.693	0.307
H33.0 Retinal detachment with retinal break	0.693	0.307
E83.1 Disorders of iron metabolism	0.693	0.307
U80 Agent resistant to penicillin and related antibiotics	0.691	0.309
S66 Injury of muscle and tendon at wrist and hand level	0.691	0.309
N85.8 Other specified noninflammatory disorders of uterus	0.691	0.309
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.690	0.310
N95.1 Menopausal and female climacteric states	0.689	0.311
N87 Dysplasia of cervix uteri	0.689	0.311
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.689	0.311
A48 Other bacterial diseases, not elsewhere classified	0.688	0.312
A44 Bartonellosis	0.688	0.312
A43 Nocardiosis	0.688	0.312
A42 Actinomycosis	0.688	0.312
A40 Streptococcal septicaemia	0.688	0.312
A39 Meningococcal infection	0.688	0.312
A37 Whooping cough	0.688	0.312
A36 Diphtheria	0.688	0.312
A32 Listeriosis	0.688	0.312
A31 Infection due to other mycobacteria	0.688	0.312
A30 Leprosy [Hansen's disease]	0.688	0.312
A38 Scarlet fever	0.688	0.312
A35 Other tetanus	0.688	0.312
A34 Obstetrical tetanus	0.688	0.312
A33 Tetanus neonatorum	0.688	0.312
C73 Malignant neoplasm of thyroid gland	0.687	0.313
T88.7 Unspecified adverse effect of drug or medicament	0.687	0.313
Y40.8 Other systemic antibiotics	0.687	0.313
T46 Poisoning by agents primarily affecting the cardiovascular system	0.686	0.313
M11 Other crystal arthropathies	0.686	0.314
A41.4 Septicaemia due to anaerobes	0.686	0.314
A41.3 Septicaemia due to Haemophilus influenzae	0.686	0.314
A41.1 Septicaemia due to other specified staphylococcus	0.686	0.314
M20-M25 Other joint disorders	0.684	0.316
B15-B19 Viral hepatitis	0.682	0.318
D47.2 Monoclonal gammopathy	0.682	0.318
H33.2 Serous retinal detachment	0.680	0.320
Y40.3 Macrolides	0.679	0.320
H36 Retinal disorders in diseases classified elsewhere	0.679	0.321
M14 Arthropathies in other diseases classified elsewhere	0.679	0.321
M12 Other specific arthropathies	0.679	0.321
M09 Juvenile arthritis in diseases classified elsewhere	0.679	0.321
M08 Juvenile arthritis	0.679	0.321
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.679	0.321
H66 Suppurative and unspecified otitis media	0.678	0.322
M86-M90 Other osteopathies	0.677	0.323
S70-S79 Injuries to the hip and thigh	0.677	0.323
E50-E64 Other nutritional deficiencies	0.677	0.323
D44.3 Pituitary gland	0.676	0.324
C45 Mesothelioma	0.676	0.324
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.675	0.325
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.675	0.325
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.674	0.325
H32 Chorioretinal disorders in diseases classified elsewhere	0.674	0.326
H30 Chorioretinal inflammation	0.674	0.326
C21 Malignant neoplasm of anus and anal canal	0.673	0.327
B35-B49 Mycoses	0.673	0.327
D55-D59 Haemolytic anaemias	0.671	0.329
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.671	0.329
F31 Bipolar affective disorder	0.670	0.330
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.668	0.332
H60-H62 Diseases of external ear	0.666	0.334
W00-W19 Falls	0.666	0.334
I84 Haemorrhoids	0.666	0.334
M19.01 Primary arthrosis of other joints (Shoulder region)	0.665	0.335
Y57 Other and unspecified drugs and medicaments	0.664	0.336
M77 Other enthesopathies	0.663	0.337
N71 Inflammatory disease of uterus, except cervix	0.663	0.337
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.663	0.337
H53.9 Visual disturbance, unspecified	0.662	0.338
Y52 Agents primarily affecting the cardiovascular system	0.661	0.339
D00-D09 In situ neoplasms	0.661	0.339
N84.0 Polyp of corpus uteri	0.659	0.341
I95 Hypotension	0.658	0.342
M06.8 Other specified rheumatoid arthritis	0.657	0.343
M06.4 Inflammatory polyarthropathy	0.657	0.343
M06.3 Rheumatoid nodule	0.657	0.343
M06.2 Rheumatoid bursitis	0.657	0.343
M06.1 Adult-onset Still's disease	0.657	0.343
N76 Other inflammation of vagina and vulva	0.657	0.343
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.656	0.344
Q38-Q45 Other congenital malformations of the digestive system	0.656	0.344
Q35-Q37 Cleft lip and cleft palate	0.656	0.344
Q30-Q34 Congenital malformations of the respiratory system	0.656	0.344
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.656	0.344
Q00-Q07 Congenital malformations of the nervous system	0.656	0.344
D47.1 Chronic myeloproliferative disease	0.655	0.344
D47.3 Essential (haemorrhagic) thrombocythaemia	0.654	0.345
D60-D64 Aplastic and other anaemias	0.654	0.346
H43 Disorders of vitreous body	0.654	0.346
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.653	0.347
F70-F79 Mental retardation	0.653	0.347
F60-F69 Disorders of adult personality and behaviour	0.653	0.347
E83.5 Disorders of calcium metabolism	0.653	0.347
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.653	0.347
C26 Malignant neoplasm of other and ill-defined digestive organs	0.653	0.347
E40-E46 Malnutrition	0.651	0.349
Y59 Other and unspecified vaccines and biological substances	0.646	0.354
Y58 Bacterial vaccines	0.646	0.354
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.646	0.354
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.646	0.354
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.646	0.354
Y53 Agents primarily affecting the gastro-intestinal system	0.646	0.354
Y50 Central nervous system stimulants, not elsewhere classified	0.646	0.354
Y49 Psychotropic drugs, not elsewhere classified	0.646	0.354
Y48 Anaesthetics and therapeutic gases	0.646	0.354
Y47 Sedatives, hypnotics and antianxiety drugs	0.646	0.354
Y46 Antiepileptics and anti-Parkinsonism drugs	0.646	0.354
Y41 Other systemic anti-infectives and antiparasitics	0.646	0.354
F99-F99 Unspecified mental disorder	0.646	0.354
M79 Other soft tissue disorders, not elsewhere classified	0.643	0.357
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.641	0.359
C18 Malignant neoplasm of colon	0.641	0.359
V10-V19 Pedal cyclist injured in transport accident	0.641	0.359
C25.9 Pancreas, unspecified	0.641	0.359
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.641	0.359
C17 Malignant neoplasm of small intestine	0.641	0.359
C16 Malignant neoplasm of stomach	0.641	0.359
C23 Malignant neoplasm of gallbladder	0.641	0.359
N88 Other noninflammatory disorders of cervix uteri	0.641	0.359
C48.2 Peritoneum, unspecified	0.640	0.360
S89 Other and unspecified injuries of lower leg	0.640	0.360
D72 Other disorders of white blood cells	0.640	0.360
D37.9 Digestive organ, unspecified	0.640	0.360
D37.6 Liver, gallbladder and bile ducts	0.640	0.360
D37.3 Appendix	0.640	0.360
D37.1 Stomach	0.640	0.360
N20-N23 Urolithiasis	0.639	0.361
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.639	0.361
M06.98 Rheumatoid arthritis, unspecified (Other)	0.637	0.363
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.637	0.363
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.637	0.363
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.637	0.363
D75.8 Other specified diseases of blood and blood-forming organs	0.635	0.365
T83.3 Mechanical complication of intra-uterine contraceptive device	0.635	0.365
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.634	0.366
M70 Soft tissue disorders related to use, overuse and pressure	0.634	0.366
N60.3 Fibrosclerosis of breast	0.633	0.367
N60.0 Solitary cyst of breast	0.633	0.367
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.633	0.367
N85.2 Hypertrophy of uterus	0.632	0.368
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.631	0.369
D74 Methaemoglobinaemia	0.631	0.369
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.631	0.369
D71 Functional disorders of polymorphonuclear neutrophils	0.631	0.369
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.630	0.370
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.630	0.370
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.630	0.370
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.630	0.370
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.630	0.370
T41 Poisoning by anaesthetics and therapeutic gases	0.630	0.370
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.630	0.370
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.630	0.370
T36 Poisoning by systemic antibiotics	0.630	0.370
N90.6 Hypertrophy of vulva	0.630	0.370
D86 Sarcoidosis	0.629	0.371
T14 Injury of unspecified body region	0.629	0.371
Q23.1 Congenital insufficiency of aortic valve	0.628	0.372
S82.5 Fracture of medial malleolus	0.627	0.373
W22.9 Unspecified place	0.626	0.374
M07 Psoriatic and enteropathic arthropathies	0.625	0.374
I22 Subsequent myocardial infarction	0.625	0.375
Y40.0 Penicillins	0.624	0.376
S88 Traumatic amputation of lower leg	0.624	0.376
S87 Crushing injury of lower leg	0.624	0.376
S86 Injury of muscle and tendon at lower leg level	0.624	0.376
S85 Injury of blood vessels at lower leg level	0.624	0.376
S84 Injury of nerves at lower leg level	0.624	0.376
H35.9 Retinal disorder, unspecified	0.624	0.376
H35.7 Separation of retinal layers	0.624	0.376
H35.6 Retinal haemorrhage	0.624	0.376
H35.5 Hereditary retinal dystrophy	0.624	0.376
H35.4 Peripheral retinal degeneration	0.624	0.376
H35.2 Other proliferative retinopathy	0.624	0.376
H35.1 Retinopathy of prematurity	0.624	0.376
Q27 Other congenital malformations of peripheral vascular system	0.624	0.376
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.623	0.377
N95.8 Other specified menopausal and perimenopausal disorders	0.623	0.377
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident	0.623	0.377
I84.2 Internal haemorrhoids without complication	0.623	0.377
B02 Zoster [herpes zoster]	0.622	0.377
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.622	0.378
S83.2 Tear of meniscus, current	0.622	0.378
T88.9 Complication of surgical and medical care, unspecified	0.621	0.379
T88.5 Other complications of anaesthesia	0.621	0.379
T88.4 Failed or difficult intubation	0.621	0.379
T88.3 Malignant hyperthermia due to anaesthesis	0.621	0.379
T88.2 Shock due to anaesthesia	0.621	0.379
T88.1 Other complications following immunisation, not elsewhere classified	0.621	0.379
T88.0 Infection following immunisation	0.621	0.379
C50-C50 Malignant neoplasm of breast	0.621	0.379
E83.4 Disorders of magnesium metabolism	0.620	0.380
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.620	0.380
S50-S59 Injuries to the elbow and forearm	0.618	0.381
H31.0 Chorioretinal scars	0.618	0.382
N60.4 Mammary duct ectasia	0.618	0.382
C49 Malignant neoplasm of other connective and soft tissue	0.618	0.382
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.618	0.382
C46 Kaposi's sarcoma	0.618	0.382
N98 Complications associated with artificial fertilisation	0.617	0.383
N91 Absent, scanty and rare menstruation	0.617	0.383
N82 Fistulae involving female genital tract	0.617	0.383
N96 Habitual aborter	0.617	0.383
N97 Female infertility	0.617	0.383
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.617	0.383
E85 Amyloidosis	0.615	0.384
E84 Cystic fibrosis	0.615	0.384
E79 Disorders of purine and pyrimidine metabolism	0.615	0.384
E77 Disorders of glycoprotein metabolism	0.615	0.384
E76 Disorders of glycosaminoglycan metabolism	0.615	0.384
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.615	0.384
E74 Other disorders of carbohydrate metabolism	0.615	0.384
E73 Lactose intolerance	0.615	0.384
E72 Other disorders of amino-acid metabolism	0.615	0.384
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.615	0.384
E70 Disorders of aromatic amino-acid metabolism	0.615	0.384
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.615	0.384
T17 Foreign body in respiratory tract	0.614	0.386
I21 Acute myocardial infarction	0.614	0.386
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.613	0.386
Q60-Q64 Congenital malformations of the urinary system	0.613	0.386
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.613	0.387
C54 Malignant neoplasm of corpus uteri	0.612	0.388
H53.4 Visual field defects	0.612	0.388
N05 Unspecified nephritic syndrome	0.611	0.389
Y51 Drugs primarily affecting the autonomic nervous system	0.611	0.389
N95.9 Menopausal and perimenopausal disorder, unspecified	0.609	0.391
N95.3 States associated with artificial menopause	0.609	0.391
E87.2 Acidosis	0.609	0.391
S62 Fracture at wrist and hand level	0.608	0.392
H53.8 Other visual disturbances	0.608	0.392
U80.1 Methicillin resistant agent	0.608	0.392
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.608	0.392
N70 Salpingitis and oophoritis	0.608	0.392
C56 Malignant neoplasm of ovary	0.608	0.392
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.607	0.392
N17.8 Other acute renal failure	0.606	0.393
N17.2 Acute renal failure with medullary necrosis	0.606	0.393
N17.1 Acute renal failure with acute cortical necrosis	0.606	0.393
N17.0 Acute renal failure with tubular necrosis	0.606	0.393
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.606	0.394

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations