TreeWAS – Variant ID: rs190738582

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XI Diseases of the digestive system	0.001	0.998
# Top node	0.001	0.998
K50-K52 Noninfective enteritis and colitis	0.001	0.998
K55-K64 Other diseases of intestines	0.001	0.998
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.001	0.998
K52 Other non-infective gastro-enteritis and colitis	0.001	0.998
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.001	0.998
K40-K46 Hernia	0.001	0.998
K57 Diverticular disease of intestine	0.001	0.998
K57.3 Diverticular disease of large intestine without perforation or abscess	0.001	0.998
Chapter IX Diseases of the circulatory system	0.001	0.998
K90-K93 Other diseases of the digestive system	0.001	0.999
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.001	0.999
K70-K77 Diseases of liver	0.001	0.999
K65-K67 Diseases of peritoneum	0.001	0.999
K35-K38 Diseases of appendix	0.001	0.999
K20-K31 Diseases of oesophagus, stomach and duodenum	0.001	0.999
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.999
R50-R69 General symptoms and signs	0.001	0.999
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.001	0.999
Chapter XXII Codes for special purposes	0.001	0.999
Chapter XXI Factors influencing health status and contact with health services	0.001	0.999
Chapter XX External causes of morbidity and mortality	0.001	0.999
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.001	0.999
Chapter XVI Certain conditions originating in the perinatal period	0.001	0.999
Chapter XV Pregnancy, childbirth and the puerperium	0.001	0.999
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.001	0.999
Chapter XIV Diseases of the genitourinary system	0.001	0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.001	0.999
Chapter XII Diseases of the skin and subcutaneous tissue	0.001	0.999
Chapter X Diseases of the respiratory system	0.001	0.999
Chapter VIII Diseases of the ear and mastoid process	0.001	0.999
Chapter VII Diseases of the eye and adnexa	0.001	0.999
Chapter VI Diseases of the nervous system	0.001	0.999
Chapter V Mental and behavioural disorders	0.001	0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999
Chapter II Neoplasms	0.001	0.999
Chapter I Certain infectious and parasitic diseases	0.001	0.999
K40 Inguinal hernia	0.001	0.999
K51 Ulcerative colitis	0.001	0.999
K50 Crohn's disease [regional enteritis]	0.001	0.999
I20-I25 Ischaemic heart diseases	0.001	0.999
K64 Haemorrhoids and perianal venous thrombosis	0.001	0.999
K63 Other diseases of intestine	0.001	0.999
K62 Other diseases of anus and rectum	0.001	0.999
K61 Abscess of anal and rectal regions	0.001	0.999
K60 Fissure and fistula of anal and rectal regions	0.001	0.999
K59 Other functional intestinal disorders	0.001	0.999
K58 Irritable bowel syndrome	0.001	0.999
K56 Paralytic ileus and intestinal obstruction without hernia	0.001	0.999
K55 Vascular disorders of intestine	0.001	0.999
R69 Unknown and unspecified causes of morbidity	0.001	0.999
R95-R99 Ill-defined and unknown causes of mortality	0.001	0.999
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.001	0.999
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.001	0.999
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.001	0.999
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.001	0.999
R47-R49 Symptoms and signs involving speech and voice	0.001	0.999
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.001	0.999
R30-R39 Symptoms and signs involving the urinary system	0.001	0.999
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.001	0.999
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.001	0.999
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.001	0.999
K52.8 Other specified non-infective gastro-enteritis and colitis	0.001	0.999
K52.3 Indeterminate colitis	0.001	0.999
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.001	0.999
K52.1 Toxic gastro-enteritis and colitis	0.001	0.999
K52.0 Gastro-enteritis and colitis due to radiation	0.001	0.999
R07 Pain in throat and chest	0.001	0.999
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.001	0.999
K46 Unspecified abdominal hernia	0.001	0.999
K45 Other abdominal hernia	0.001	0.999
K44 Diaphragmatic hernia	0.001	0.999
K43 Ventral hernia	0.001	0.999
K42 Umbilical hernia	0.001	0.999
K41 Femoral hernia	0.001	0.999
E70-E90 Metabolic disorders	0.001	0.999
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.001	0.999
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.001	0.999
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.001	0.999
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.001	0.999
K57.2 Diverticular disease of large intestine with perforation and abscess	0.001	0.999
K57.1 Diverticular disease of small intestine without perforation or abscess	0.001	0.999
K57.0 Diverticular disease of small intestine with perforation and abscess	0.001	0.999
R07.4 Chest pain, unspecified	0.001	0.999
I20 Angina pectoris	0.001	0.999
I95-I99 Other and unspecified disorders of the circulatory system	0.001	0.999
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.001	0.999
I70-I79 Diseases of arteries, arterioles and capillaries	0.001	0.999
I60-I69 Cerebrovascular diseases	0.001	0.999
I30-I52 Other forms of heart disease	0.001	0.999
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.001	0.999
I05-I09 Chronic rheumatic heart diseases	0.001	0.999
I00-I02 Acute rheumatic fever	0.001	0.999
E65-E68 Obesity and other hyperalimentation	0.001	0.999
E50-E64 Other nutritional deficiencies	0.001	0.999
E40-E46 Malnutrition	0.001	0.999
E20-E35 Disorders of other endocrine glands	0.001	0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.001	0.999
E10-E14 Diabetes mellitus	0.001	0.999
E00-E07 Disorders of thyroid gland	0.001	0.999
I10-I15 Hypertensive diseases	0.001	0.999
I20.9 Angina pectoris, unspecified	0.001	0.999
K14 Diseases of tongue	0.001	0.999
K13 Other diseases of lip and oral mucosa	0.001	0.999
K12 Stomatitis and related lesions	0.001	0.999
K11 Diseases of salivary glands	0.001	0.999
K10 Other diseases of jaws	0.001	0.999
K09 Cysts of oral region, not elsewhere classified	0.001	0.999
K08 Other disorders of teeth and supporting structures	0.001	0.999
K07 Dentofacial anomalies [including malocclusion]	0.001	0.999
K06 Other disorders of gingiva and edentulous alveolar ridge	0.001	0.999
K05 Gingivitis and periodontal diseases	0.001	0.999
K04 Diseases of pulp and periapical tissues	0.001	0.999
K03 Other diseases of hard tissues of teeth	0.001	0.999
K02 Dental caries	0.001	0.999
K01 Embedded and impacted teeth	0.001	0.999
K00 Disorders of tooth development and eruption	0.001	0.999
K31 Other diseases of stomach and duodenum	0.001	0.999
K29 Gastritis and duodenitis	0.001	0.999
K28 Gastrojejunal ulcer	0.001	0.999
K27 Peptic ulcer, site unspecified	0.001	0.999
K26 Duodenal ulcer	0.001	0.999
K25 Gastric ulcer	0.001	0.999
K23 Disorders of oesophagus in diseases classified elsewhere	0.001	0.999
K22 Other diseases of oesophagus	0.001	0.999
K21 Gastro-oesophageal reflux disease	0.001	0.999
K30 Dyspepsia	0.001	0.999
K20 Oesophagitis	0.001	0.999
K38 Other diseases of appendix	0.001	0.999
K35 Acute appendicitis	0.001	0.999
K37 Unspecified appendicitis	0.001	0.999
K36 Other appendicitis	0.001	0.999
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.001	0.999
K66 Other disorders of peritoneum	0.001	0.999
K65 Peritonitis	0.001	0.999
K77 Liver disorders in diseases classified elsewhere	0.001	0.999
K76 Other diseases of liver	0.001	0.999
K75 Other inflammatory liver diseases	0.001	0.999
K74 Fibrosis and cirrhosis of liver	0.001	0.999
K73 Chronic hepatitis, not elsewhere classified	0.001	0.999
K72 Hepatic failure, not elsewhere classified	0.001	0.999
K71 Toxic liver disease	0.001	0.999
K70 Alcoholic liver disease	0.001	0.999
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.001	0.999
K86 Other diseases of pancreas	0.001	0.999
K85 Acute pancreatitis	0.001	0.999
K83 Other diseases of biliary tract	0.001	0.999
K82 Other diseases of gallbladder	0.001	0.999
K81 Cholecystitis	0.001	0.999
K80 Cholelithiasis	0.001	0.999
K93 Disorders of other digestive organs in diseases classified elsewhere	0.001	0.999
K92 Other diseases of digestive system	0.001	0.999
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.001	0.999
K90 Intestinal malabsorption	0.001	0.999
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.001	0.999
R06 Abnormalities of breathing	0.001	0.999
R04 Haemorrhage from respiratory passages	0.001	0.999
R03 Abnormal blood-pressure reading, without diagnosis	0.001	0.999
R01 Cardiac murmurs and other cardiac sounds	0.001	0.999
R00 Abnormalities of heart beat	0.001	0.999
R05 Cough	0.001	0.999
R02 Gangrene, not elsewhere classified	0.001	0.999
R68 Other general symptoms and signs	0.001	0.999
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.001	0.999
R63 Symptoms and signs concerning food and fluid intake	0.001	0.999
R62 Lack of expected normal physiological development	0.001	0.999
R61 Hyperhidrosis	0.001	0.999
R60 Oedema, not elsewhere classified	0.001	0.999
R59 Enlarged lymph nodes	0.001	0.999
R57 Shock, not elsewhere classified	0.001	0.999
R56 Convulsions, not elsewhere classified	0.001	0.999
R52 Pain, not elsewhere classified	0.001	0.999
R50 Fever of unknown origin	0.001	0.999
R64 Cachexia	0.001	0.999
R58 Haemorrhage, not elsewhere classified	0.001	0.999
R55 Syncope and collapse	0.001	0.999
R54 Senility	0.001	0.999
R53 Malaise and fatigue	0.001	0.999
R51 Headache	0.001	0.999
B99-B99 Other infectious diseases	0.001	0.999
B95-B98 Bacterial, viral and other infectious agents	0.001	0.999
B90-B94 Sequelae of infectious and parasitic diseases	0.001	0.999
B85-B89 Pediculosis, acariasis and other infestations	0.001	0.999
B65-B83 Helminthiases	0.001	0.999
B50-B64 Protozoal diseases	0.001	0.999
B35-B49 Mycoses	0.001	0.999
B25-B34 Other viral diseases	0.001	0.999
B20-B24 Human immunodeficiency virus [HIV] disease	0.001	0.999
B15-B19 Viral hepatitis	0.001	0.999
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.001	0.999
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.001	0.999
A80-A89 Viral infections of the central nervous system	0.001	0.999
A75-A79 Rickettsioses	0.001	0.999
A70-A74 Other diseases caused by chlamydiae	0.001	0.999
A65-A69 Other spirochaetal diseases	0.001	0.999
A50-A64 Infections with a predominantly sexual mode of transmission	0.001	0.999
A30-A49 Other bacterial diseases	0.001	0.999
A20-A28 Certain zoonotic bacterial diseases	0.001	0.999
A15-A19 Tuberculosis	0.001	0.999
A00-A09 Intestinal infectious diseases	0.001	0.999
D37-D48 Neoplasms of uncertain or unknown behaviour	0.001	0.999
D10-D36 Benign neoplasms	0.001	0.999
D00-D09 In situ neoplasms	0.001	0.999
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.001	0.999
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.001	0.999
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.001	0.999
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.001	0.999
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.001	0.999
C64-C68 Malignant neoplasms of urinary tract	0.001	0.999
C60-C63 Malignant neoplasms of male genital organs	0.001	0.999
C51-C58 Malignant neoplasms of female genital organs	0.001	0.999
C50-C50 Malignant neoplasm of breast	0.001	0.999
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.001	0.999
C43-C44 Melanoma and other malignant neoplasms of skin	0.001	0.999
C40-C41 Malignant neoplasms of bone and articular cartilage	0.001	0.999
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.001	0.999
C15-C26 Malignant neoplasms of digestive organs	0.001	0.999
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.001	0.999
D80-D89 Certain disorders involving the immune mechanism	0.001	0.999
D70-D77 Other diseases of blood and blood-forming organs	0.001	0.999
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.001	0.999
D60-D64 Aplastic and other anaemias	0.001	0.999
D55-D59 Haemolytic anaemias	0.001	0.999
D50-D53 Nutritional anaemias	0.001	0.999
F99-F99 Unspecified mental disorder	0.001	0.999
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.001	0.999
F80-F89 Disorders of psychological development	0.001	0.999
F70-F79 Mental retardation	0.001	0.999
F60-F69 Disorders of adult personality and behaviour	0.001	0.999
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.001	0.999
F40-F48 Neurotic, stress-related and somatoform disorders	0.001	0.999
F30-F39 Mood [affective] disorders	0.001	0.999
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.001	0.999
F00-F09 Organic, including symptomatic, mental disorders	0.001	0.999
G90-G99 Other disorders of the nervous system	0.001	0.999
G80-G83 Cerebral palsy and other paralytic syndromes	0.001	0.999
G70-G73 Diseases of myoneural junction and muscle	0.001	0.999
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.001	0.999
G50-G59 Nerve, nerve root and plexus disorders	0.001	0.999
G40-G47 Episodic and paroxysmal disorders	0.001	0.999
G35-G37 Demyelinating diseases of the central nervous system	0.001	0.999
G30-G32 Other degenerative diseases of the nervous system	0.001	0.999
G20-G26 Extrapyramidal and movement disorders	0.001	0.999
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.001	0.999
G00-G09 Inflammatory diseases of the central nervous system	0.001	0.999
H55-H59 Other disorders of eye and adnexa	0.001	0.999
H53-H54 Visual disturbances and blindness	0.001	0.999
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.001	0.999
H46-H48 Disorders of optic nerve and visual pathways	0.001	0.999
H43-H45 Disorders of vitreous body and globe	0.001	0.999
H40-H42 Glaucoma	0.001	0.999
H30-H36 Disorders of choroid and retina	0.001	0.999
H25-H28 Disorders of lens	0.001	0.999
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.001	0.999
H10-H13 Disorders of conjunctiva	0.001	0.999
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.001	0.999
H90-H95 Other disorders of ear	0.001	0.999
H80-H83 Diseases of inner ear	0.001	0.999
H65-H75 Diseases of middle ear and mastoid	0.001	0.999
H60-H62 Diseases of external ear	0.001	0.999
J95-J99 Other diseases of the respiratory system	0.001	0.999
J90-J94 Other diseases of pleura	0.001	0.999
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.001	0.999
J80-J84 Other respiratory diseases principally affecting the interstitium	0.001	0.999
J60-J70 Lung diseases due to external agents	0.001	0.999
J40-J47 Chronic lower respiratory diseases	0.001	0.999
J30-J39 Other diseases of upper respiratory tract	0.001	0.999
J20-J22 Other acute lower respiratory infections	0.001	0.999
J09-J18 Influenza and pneumonia	0.001	0.999
J00-J06 Acute upper respiratory infections	0.001	0.999
L80-L99 Other disorders of the skin and subcutaneous tissue	0.001	0.999
L60-L75 Disorders of skin appendages	0.001	0.999
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.001	0.999
L50-L54 Urticaria and erythema	0.001	0.999
L40-L45 Papulosquamous disorders	0.001	0.999
L20-L30 Dermatitis and eczema	0.001	0.999
L10-L14 Bullous disorders	0.001	0.999
L00-L08 Infections of the skin and subcutaneous tissue	0.001	0.999
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.001	0.999
M91-M94 Chondropathies	0.001	0.999
M86-M90 Other osteopathies	0.001	0.999
M80-M85 Disorders of bone density and structure	0.001	0.999
M70-M79 Other soft tissue disorders	0.001	0.999
M65-M68 Disorders of synovium and tendon	0.001	0.999
M60-M63 Disorders of muscles	0.001	0.999
M50-M54 Other dorsopathies	0.001	0.999
M45-M49 Spondylopathies	0.001	0.999
M40-M43 Deforming dorsopathies	0.001	0.999
M20-M25 Other joint disorders	0.001	0.999
M15-M19 Arthrosis	0.001	0.999
M05-M14 Inflammatory polyarthropathies	0.001	0.999
M00-M03 Infectious arthropathies	0.001	0.999
N99-N99 Other disorders of the genitourinary system	0.001	0.999
N80-N98 Noninflammatory disorders of female genital tract	0.001	0.999
N70-N77 Inflammatory diseases of female pelvic organs	0.001	0.999
N60-N64 Disorders of breast	0.001	0.999
N40-N51 Diseases of male genital organs	0.001	0.999
N30-N39 Other diseases of urinary system	0.001	0.999
N25-N29 Other disorders of kidney and ureter	0.001	0.999
N20-N23 Urolithiasis	0.001	0.999
N17-N19 Renal failure	0.001	0.999
N10-N16 Renal tubulo-interstitial diseases	0.001	0.999
N00-N08 Glomerular diseases	0.001	0.999
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.999
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.001	0.999
T79-T79 Certain early complications of trauma	0.001	0.999
T66-T78 Other and unspecified effects of external causes	0.001	0.999
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.001	0.999
T36-T50 Poisoning by drugs, medicaments and biological substances	0.001	0.999
T33-T35 Frostbite	0.001	0.999
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.001	0.999
T26-T28 Burns and corrosions confined to eye and internal organs	0.001	0.999
T20-T25 Burns and corrosions of external body surface, specified by site	0.001	0.999
T15-T19 Effects of foreign body entering through natural orifice	0.001	0.999
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.001	0.999
T00-T07 Injuries involving multiple body regions	0.001	0.999
S90-S99 Injuries to the ankle and foot	0.001	0.999
S80-S89 Injuries to the knee and lower leg	0.001	0.999
S70-S79 Injuries to the hip and thigh	0.001	0.999
S60-S69 Injuries to the wrist and hand	0.001	0.999
S50-S59 Injuries to the elbow and forearm	0.001	0.999
S40-S49 Injuries to the shoulder and upper arm	0.001	0.999
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.001	0.999
S20-S29 Injuries to the thorax	0.001	0.999
S10-S19 Injuries to the neck	0.001	0.999
S00-S09 Injuries to the head	0.001	0.999
O94-O99 Other obstetric conditions, not elsewhere classified	0.001	0.999
O85-O92 Complications predominantly related to the puerperium	0.001	0.999
O80-O84 Delivery	0.001	0.999
O60-O75 Complications of labour and delivery	0.001	0.999
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.001	0.999
O20-O29 Other maternal disorders predominantly related to pregnancy	0.001	0.999
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.001	0.999
O00-O08 Pregnancy with abortive outcome	0.001	0.999
P90-P96 Other disorders originating in the perinatal period	0.001	0.999
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.001	0.999
P75-P78 Digestive system disorders of fetus and newborn	0.001	0.999
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.001	0.999
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.001	0.999
P35-P39 Infections specific to the perinatal period	0.001	0.999
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.001	0.999
P10-P15 Birth trauma	0.001	0.999
P05-P08 Disorders related to length of gestation and fetal growth	0.001	0.999
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.001	0.999
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.999
Q80-Q89 Other congenital malformations	0.001	0.999
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.001	0.999
Q60-Q64 Congenital malformations of the urinary system	0.001	0.999
Q50-Q56 Congenital malformations of genital organs	0.001	0.999
Q38-Q45 Other congenital malformations of the digestive system	0.001	0.999
Q35-Q37 Cleft lip and cleft palate	0.001	0.999
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.999
Q20-Q28 Congenital malformations of the circulatory system	0.001	0.999
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.001	0.999
Q00-Q07 Congenital malformations of the nervous system	0.001	0.999
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.001	0.999
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.001	0.999
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.001	0.999
Y60-Y69 Misadventures to patients during surgical and medical care	0.001	0.999
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.001	0.999
Y35-Y36 Legal intervention and operations of war	0.001	0.999
Y10-Y34 Event of undetermined intent	0.001	0.999
Y00-Y09 Assault	0.001	0.999
X85-X99 Assault	0.001	0.999
X60-X84 Intentional self-harm	0.001	0.999
X58-X59 Accidental exposure to other and unspecified factors	0.001	0.999
X50-X57 Overexertion, travel and privation	0.001	0.999
X40-X49 Accidental poisoning by and exposure to noxious substances	0.001	0.999
X30-X39 Exposure to forces of nature	0.001	0.999
X20-X29 Contact with venomous animals and plants	0.001	0.999
X10-X19 Contact with heat and hot substances	0.001	0.999
X00-X09 Exposure to smoke, fire and flames	0.001	0.999
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.001	0.999
W75-W84 Other accidental threats to breathing	0.001	0.999
W65-W74 Accidental drowning and submersion	0.001	0.999
W50-W64 Exposure to animate mechanical forces	0.001	0.999
W20-W49 Exposure to inanimate mechanical forces	0.001	0.999
W00-W19 Falls	0.001	0.999
V98-V99 Other and unspecified transport accidents	0.001	0.999
V95-V97 Air and space transport accidents	0.001	0.999
V90-V94 Water transport accidents	0.001	0.999
V80-V89 Other land transport accidents	0.001	0.999
V70-V79 Bus occupant injured in transport accident	0.001	0.999
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.001	0.999
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.001	0.999
V40-V49 Car occupant injured in transport accident	0.001	0.999
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.001	0.999
V20-V29 Motorcycle rider injured in transport accident	0.001	0.999
V10-V19 Pedal cyclist injured in transport accident	0.001	0.999
V01-V09 Pedestrian injured in transport accident	0.001	0.999
Z70-Z76 Persons encountering health services in other circumstances	0.001	0.999
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.001	0.999
Z40-Z54 Persons encountering health services for specific procedures and health care	0.001	0.999
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.001	0.999
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.001	0.999
Z00-Z13 Persons encountering health services for examination and investigation	0.001	0.999
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.001	0.999
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.001	0.999
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.001	0.999
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.001	0.999
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.001	0.999
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.001	0.999
K40.1 Bilateral inguinal hernia, with gangrene	0.001	0.999
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.001	0.999
K50.9 Crohn's disease, unspecified	0.001	0.999
K50.8 Other Crohn's disease	0.001	0.999
K50.1 Crohn's disease of large intestine	0.001	0.999
K50.0 Crohn's disease of small intestine	0.001	0.999
K51.9 Ulcerative colitis, unspecified	0.001	0.999
K51.8 Other ulcerative colitis	0.001	0.999
K51.5 Mucosal proctocolitis	0.001	0.999
K51.4 Pseudopolyposis of colon	0.001	0.999
K51.3 Ulcerative (chronic) rectosigmoiditis	0.001	0.999
K51.2 Ulcerative (chronic) proctitis	0.001	0.999
K51.1 Ulcerative (chronic) ileocolitis	0.001	0.999
K51.0 Ulcerative (chronic) enterocolitis	0.001	0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.001	0.999
I25 Chronic ischaemic heart disease	0.001	0.999
I24 Other acute ischaemic heart diseases	0.001	0.999
I23 Certain current complications following acute myocardial infarction	0.001	0.999
I22 Subsequent myocardial infarction	0.001	0.999
I21 Acute myocardial infarction	0.001	0.999
K55.9 Vascular disorder of intestine, unspecified	0.001	0.999
K55.8 Other vascular disorders of intestine	0.001	0.999
K55.2 Angiodysplasia of colon	0.001	0.999
K55.1 Chronic vascular disorders of intestine	0.001	0.999
K55.0 Acute vascular disorders of intestine	0.001	0.999
K56.7 Ileus, unspecified	0.001	0.999
K56.6 Other and unspecified intestinal obstruction	0.001	0.999
K56.5 Intestinal adhesions [bands] with obstruction	0.001	0.999
K56.4 Other impaction of intestine	0.001	0.999
K56.3 Gallstone ileus	0.001	0.999
K56.2 Volvulus	0.001	0.999
K56.1 Intussusception	0.001	0.999
K56.0 Paralytic ileus	0.001	0.999
K58.9 Irritable bowel syndrome without diarrhoea	0.001	0.999
K58.0 Irritable bowel syndrome with diarrhoea	0.001	0.999
K59.9 Functional intestinal disorder, unspecified	0.001	0.999
K59.8 Other specified functional intestinal disorders	0.001	0.999
K59.4 Anal spasm	0.001	0.999
K59.3 Megacolon, not elsewhere classified	0.001	0.999
K59.2 Neurogenic bowel, not elsewhere classified	0.001	0.999
K59.1 Functional diarrhoea	0.001	0.999
K59.0 Constipation	0.001	0.999
K60.5 Anorectal fistula	0.001	0.999
K60.4 Rectal fistula	0.001	0.999
K60.3 Anal fistula	0.001	0.999
K60.2 Anal fissure, unspecified	0.001	0.999
K60.1 Chronic anal fissure	0.001	0.999
K60.0 Acute anal fissure	0.001	0.999
K61.4 Intrasphincteric abscess	0.001	0.999
K61.3 Ischiorectal abscess	0.001	0.999
K61.2 Anorectal abscess	0.001	0.999
K61.1 Rectal abscess	0.001	0.999
K61.0 Anal abscess	0.001	0.999
K62.9 Disease of anus and rectum, unspecified	0.001	0.999
K62.8 Other specified diseases of anus and rectum	0.001	0.999
K62.7 Radiation proctitis	0.001	0.999
K62.6 Ulcer of anus and rectum	0.001	0.999
K62.5 Haemorrhage of anus and rectum	0.001	0.999
K62.4 Stenosis of anus and rectum	0.001	0.999
K62.3 Rectal prolapse	0.001	0.999
K62.2 Anal prolapse	0.001	0.999
K62.1 Rectal polyp	0.001	0.999
K62.0 Anal polyp	0.001	0.999
K63.9 Disease of intestine, unspecified	0.001	0.999
K63.8 Other specified diseases of intestine	0.001	0.999
K63.5 Polyp of colon	0.001	0.999
K63.4 Enteroptosis	0.001	0.999
K63.3 Ulcer of intestine	0.001	0.999
K63.2 Fistula of intestine	0.001	0.999
K63.1 Perforation of intestine (nontraumatic)	0.001	0.999
K63.0 Abscess of intestine	0.001	0.999
K64.9 Haemorrhoids, unspecified	0.001	0.999
K64.8 Other specified haemorrhoids	0.001	0.999
K64.5 Perianal venous thrombosis	0.001	0.999
K64.4 Residual haemorrhoidal skin tags	0.001	0.999
K64.3 Fourth degree haemorrhoids	0.001	0.999
K64.2 Third degree haemorrhoids	0.001	0.999
K64.1 Second degree haemorrhoids	0.001	0.999
K64.0 First degree haemorrhoids	0.001	0.999
R07.3 Other chest pain	0.001	0.999
R07.2 Precordial pain	0.001	0.999
R07.1 Chest pain on breathing	0.001	0.999
R07.0 Pain in throat	0.001	0.999
R19 Other symptoms and signs involving the digestive system and abdomen	0.001	0.999
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.001	0.999
R10 Abdominal and pelvic pain	0.001	0.999
R18 Ascites	0.001	0.999
R17 Unspecified jaundice	0.001	0.999
R15 Faecal incontinence	0.001	0.999
R14 Flatulence and related conditions	0.001	0.999
R13 Dysphagia	0.001	0.999
R12 Heartburn	0.001	0.999
R11 Nausea and vomiting	0.001	0.999
R23 Other skin changes	0.001	0.999

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations