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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs191800091
log Bayes Factor = 14.8331
Chromosome 14   position 27,245,961  (GRCh37) Explore rs191800091 on Ensembl!
Variant rs191800091 is part of Cluster X0042

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
F30-F39 Mood [affective] disorders
0.996 0.004 0.000
I60-I69 Cerebrovascular diseases
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
C15-C26 Malignant neoplasms of digestive organs
0.992 0.008 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.986 0.014 0.000
S00-S09 Injuries to the head
0.985 0.015 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.985 0.015 0.000
F32 Depressive episode
0.984 0.016 0.000
S20-S29 Injuries to the thorax
0.983 0.017 0.000
C18 Malignant neoplasm of colon
0.983 0.017 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.979 0.021 0.000
I95 Hypotension
0.976 0.024 0.000
F33 Recurrent depressive disorder
0.971 0.029 0.000
I67 Other cerebrovascular diseases
0.968 0.032 0.000
S80-S89 Injuries to the knee and lower leg
0.967 0.033 0.000
G40-G47 Episodic and paroxysmal disorders
0.966 0.034 0.000
Chapter I Certain infectious and parasitic diseases
0.962 0.038 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.961 0.039 0.000
G90-G99 Other disorders of the nervous system
0.959 0.041 0.000
I95.1 Orthostatic hypotension
0.959 0.041 0.000
S27 Injury of other and unspecified intrathoracic organs
0.958 0.042 0.000
C18.9 Colon, unspecified
0.952 0.048 0.000
C79 Secondary malignant neoplasm of other sites
0.952 0.048 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.942 0.058 0.000
I67.9 Cerebrovascular disease, unspecified
0.940 0.060 0.000
F33.9 Recurrent depressive disorder, unspecified
0.939 0.061 0.000
E20-E35 Disorders of other endocrine glands
0.937 0.063 0.000
I63 Cerebral infarction
0.937 0.063 0.000
G47 Sleep disorders
0.933 0.067 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.930 0.070 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.928 0.072 0.000
R50-R69 General symptoms and signs
0.928 0.072 0.000
C78.2 Secondary malignant neoplasm of pleura
0.924 0.076 0.000
C51-C58 Malignant neoplasms of female genital organs
0.921 0.079 0.000
S00 Superficial injury of head
0.917 0.083 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.917 0.083 0.000
G70-G73 Diseases of myoneural junction and muscle
0.914 0.086 0.000
C18.2 Ascending colon
0.913 0.087 0.000
S27.0 Traumatic pneumothorax
0.913 0.087 0.000
G47.3 Sleep apnoea
0.912 0.088 0.000
B35-B49 Mycoses
0.912 0.088 0.000
E00-E07 Disorders of thyroid gland
0.905 0.095 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.905 0.095 0.000
R50 Fever of unknown origin
0.905 0.095 0.000
I69 Sequelae of cerebrovascular disease
0.904 0.096 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.904 0.096 0.000
R51 Headache
0.900 0.100 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.899 0.101 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.897 0.103 0.000
R50.9 Fever, unspecified
0.891 0.109 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.887 0.113 0.000
N84 Polyp of female genital tract
0.886 0.114 0.000
R01 Cardiac murmurs and other cardiac sounds
0.883 0.117 0.000
R01.1 Cardiac murmur, unspecified
0.882 0.118 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.880 0.120 0.000
Chapter XIV Diseases of the genitourinary system
0.879 0.121 0.000
S82 Fracture of lower leg, including ankle
0.878 0.122 0.000
D60-D64 Aplastic and other anaemias
0.878 0.122 0.000
I95.9 Hypotension, unspecified
0.877 0.123 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.877 0.123 0.000
G44 Other headache syndromes
0.876 0.124 0.000
N80 Endometriosis
0.876 0.124 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.873 0.127 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.873 0.127 0.000
F32.1 Moderate depressive episode
0.868 0.132 0.000
N84.0 Polyp of corpus uteri
0.863 0.137 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.862 0.138 0.000
B37 Candidiasis
0.858 0.142 0.000
E27 Other disorders of adrenal gland
0.858 0.142 0.000
Chapter VII Diseases of the eye and adnexa
0.857 0.143 0.000
G91 Hydrocephalus
0.856 0.144 0.000
Chapter XXII Codes for special purposes
0.855 0.145 0.000
F32.9 Depressive episode, unspecified
0.855 0.145 0.000
C18.4 Transverse colon
0.855 0.145 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.853 0.147 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.852 0.148 0.000
S02 Fracture of skull and facial bones
0.851 0.149 0.000
C78.7 Secondary malignant neoplasm of liver
0.849 0.151 0.000
G20-G26 Extrapyramidal and movement disorders
0.847 0.153 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.846 0.154 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.845 0.155 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.845 0.155 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.843 0.157 0.000
N80.3 Endometriosis of pelvic peritoneum
0.843 0.157 0.000
N86 Erosion and ectropion of cervix uteri
0.841 0.159 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.837 0.163 0.000
I20-I25 Ischaemic heart diseases
0.836 0.164 0.000
I61 Intracerebral haemorrhage
0.836 0.164 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.835 0.165 0.000
R53 Malaise and fatigue
0.834 0.166 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.833 0.167 0.000
C17 Malignant neoplasm of small intestine
0.831 0.169 0.000
S06 Intracranial injury
0.830 0.170 0.000
R05 Cough
0.829 0.171 0.000
D61 Other aplastic anaemias
0.829 0.171 0.000
G30-G32 Other degenerative diseases of the nervous system
0.828 0.172 0.000
H40-H42 Glaucoma
0.827 0.173 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.827 0.173 0.000
E23 Hypofunction and other disorders of pituitary gland
0.827 0.173 0.000
B37.0 Candidal stomatitis
0.825 0.175 0.000
N92 Excessive, frequent and irregular menstruation
0.820 0.180 0.000
Chapter VIII Diseases of the ear and mastoid process
0.818 0.182 0.000
S01 Open wound of head
0.818 0.182 0.000
C64-C68 Malignant neoplasms of urinary tract
0.818 0.182 0.000
G72 Other myopathies
0.817 0.183 0.000
S22.4 Multiple fractures of ribs
0.817 0.183 0.000
E29 Testicular dysfunction
0.816 0.184 0.000
S90-S99 Injuries to the ankle and foot
0.816 0.184 0.000
S32 Fracture of lumbar spine and pelvis
0.814 0.186 0.000
C80 Malignant neoplasm without specification of site
0.812 0.188 0.000
F80-F89 Disorders of psychological development
0.811 0.189 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.810 0.190 0.000
F99-F99 Unspecified mental disorder
0.808 0.191 0.000
T79-T79 Certain early complications of trauma
0.808 0.192 0.000
G93 Other disorders of brain
0.808 0.192 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.808 0.192 0.000
H40 Glaucoma
0.806 0.194 0.000
A30-A49 Other bacterial diseases
0.805 0.195 0.000
S31 Open wound of abdomen, lower back and pelvis
0.804 0.195 0.000
I60 Subarachnoid haemorrhage
0.804 0.196 0.000
N88 Other noninflammatory disorders of cervix uteri
0.802 0.198 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.802 0.198 0.000
C18.3 Hepatic flexure
0.801 0.199 0.000
G82 Paraplegia and tetraplegia
0.801 0.199 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.799 0.201 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.799 0.201 0.000
B65-B83 Helminthiases
0.799 0.201 0.000
G81 Hemiplegia
0.798 0.202 0.000
R56 Convulsions, not elsewhere classified
0.797 0.203 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.796 0.204 0.000
C79.6 Secondary malignant neoplasm of ovary
0.795 0.205 0.000
G90 Disorders of autonomic nervous system
0.795 0.205 0.000
D61.9 Aplastic anaemia, unspecified
0.793 0.207 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.792 0.208 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.791 0.208 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.790 0.210 0.000
C78.0 Secondary malignant neoplasm of lung
0.789 0.211 0.000
R55 Syncope and collapse
0.788 0.212 0.000
I62 Other nontraumatic intracranial haemorrhage
0.787 0.213 0.000
S80 Superficial injury of lower leg
0.782 0.218 0.000
S10-S19 Injuries to the neck
0.782 0.218 0.000
O60-O75 Complications of labour and delivery
0.780 0.220 0.000
C25 Malignant neoplasm of pancreas
0.778 0.221 0.000
G71 Primary disorders of muscles
0.778 0.222 0.000
S89 Other and unspecified injuries of lower leg
0.778 0.222 0.000
S22.40 Multiple fractures of ribs (closed)
0.777 0.223 0.000
S30.1 Contusion of abdominal wall
0.776 0.224 0.000
S27.8 Injury of other specified intrathoracic organs
0.775 0.224 0.000
I21 Acute myocardial infarction
0.775 0.225 0.000
E03 Other hypothyroidism
0.774 0.226 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.774 0.226 0.000
S00.8 Superficial injury of other parts of head
0.773 0.227 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.773 0.227 0.000
G20 Parkinson's disease
0.772 0.228 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.772 0.228 0.000
O00-O08 Pregnancy with abortive outcome
0.772 0.228 0.000
F34 Persistent mood [affective] disorders
0.771 0.229 0.000
B15-B19 Viral hepatitis
0.770 0.230 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.770 0.230 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.768 0.232 0.000
N80.2 Endometriosis of Fallopian tube
0.767 0.233 0.000
G47.8 Other sleep disorders
0.764 0.236 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.764 0.236 0.000
G44.2 Tension-type headache
0.764 0.236 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.763 0.237 0.000
D55-D59 Haemolytic anaemias
0.761 0.239 0.000
E04 Other non-toxic goitre
0.761 0.239 0.000
C18.7 Sigmoid colon
0.759 0.241 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.759 0.241 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.758 0.241 0.000
G46.4 Cerebellar stroke syndrome
0.758 0.242 0.000
C53 Malignant neoplasm of cervix uteri
0.757 0.243 0.000
G91.1 Obstructive hydrocephalus
0.757 0.243 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.755 0.245 0.000
N94.6 Dysmenorrhoea, unspecified
0.754 0.246 0.000
N92.3 Ovulation bleeding
0.754 0.246 0.000
S00.1 Contusion of eyelid and periocular area
0.754 0.246 0.000
S05 Injury of eye and orbit
0.752 0.248 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.752 0.248 0.000
N84.1 Polyp of cervix uteri
0.751 0.249 0.000
S82.8 Fractures of other parts of lower leg
0.751 0.249 0.000
H40.9 Glaucoma, unspecified
0.751 0.249 0.000
H90-H95 Other disorders of ear
0.750 0.250 0.000
G83 Other paralytic syndromes
0.749 0.251 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.748 0.252 0.000
G12 Spinal muscular atrophy and related syndromes
0.748 0.252 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.747 0.253 0.000
E70-E90 Metabolic disorders
0.745 0.255 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.745 0.255 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.744 0.256 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.744 0.256 0.000
S82.1 Fracture of upper end of tibia
0.744 0.256 0.000
S36 Injury of intra-abdominal organs
0.741 0.259 0.000
C91 Lymphoid leukaemia
0.739 0.261 0.000
S27.2 Traumatic heamopneumothorax
0.739 0.261 0.000
F32.0 Mild depressive episode
0.738 0.262 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.738 0.262 0.000
E23.0 Hypopituitarism
0.737 0.262 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.737 0.263 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.737 0.263 0.000
C54 Malignant neoplasm of corpus uteri
0.736 0.263 0.000
I99 Other and unspecified disorders of circulatory system
0.734 0.265 0.000
G96 Other disorders of central nervous system
0.734 0.266 0.000
N92.6 Irregular menstruation, unspecified
0.731 0.269 0.000
S27.3 Other injuries of lung
0.731 0.269 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.731 0.269 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.731 0.269 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.730 0.270 0.000
D64 Other anaemias
0.730 0.270 0.000
E29.1 Testicular hypofunction
0.730 0.270 0.000
S00.3 Superficial injury of nose
0.729 0.271 0.000
S00.9 Superficial injury of head, part unspecified
0.729 0.271 0.000
A80-A89 Viral infections of the central nervous system
0.728 0.272 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.728 0.272 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.728 0.272 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.728 0.272 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.727 0.273 0.000
C23 Malignant neoplasm of gallbladder
0.726 0.274 0.000
N84.3 Polyp of vulva
0.726 0.274 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.725 0.274 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.725 0.275 0.000
S30.0 Contusion of lower back and pelvis
0.725 0.275 0.000
N82 Fistulae involving female genital tract
0.724 0.276 0.000
S50-S59 Injuries to the elbow and forearm
0.723 0.276 0.000
E28 Ovarian dysfunction
0.723 0.277 0.000
R23 Other skin changes
0.722 0.278 0.000
E04.2 Non-toxic multinodular goitre
0.721 0.279 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.721 0.279 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I67.8 Other specified cerebrovascular diseases
0.716 0.284 0.000
S27.1 Traumatic haemothorax
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
S40-S49 Injuries to the shoulder and upper arm
0.715 0.285 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
F38 Other mood [affective] disorders
0.714 0.286 0.000
F30 Manic episode
0.714 0.286 0.000
F39 Unspecified mood [affective] disorder
0.714 0.286 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.714 0.286 0.000
S29 Other and unspecified injuries of thorax
0.714 0.286 0.000
S81 Open wound of lower leg
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
S02.1 Fracture of base of skull
0.714 0.286 0.000
O36 Maternal care for other known or suspected foetal problems
0.713 0.287 0.000
R58 Haemorrhage, not elsewhere classified
0.712 0.288 0.000
U80 Agent resistant to penicillin and related antibiotics
0.712 0.288 0.000
G72.9 Myopathy, unspecified
0.712 0.288 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.712 0.288 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.711 0.289 0.000
C15 Malignant neoplasm of oesophagus
0.711 0.289 0.000
N80.8 Other endometriosis
0.711 0.289 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.710 0.290 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.710 0.290 0.000
H40.1 Primary open-angle glaucoma
0.709 0.291 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.709 0.291 0.000
C56 Malignant neoplasm of ovary
0.709 0.291 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.708 0.292 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.707 0.293 0.000
S08 Traumatic amputation of part of head
0.706 0.294 0.000
S07 Crushing injury of head
0.706 0.294 0.000
S04 Injury of cranial nerves
0.706 0.294 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.706 0.294 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.706 0.294 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.706 0.294 0.000
S37 Injury of urinary and pelvic organs
0.706 0.294 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.706 0.294 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.706 0.294 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.706 0.294 0.000
F32.8 Other depressive episodes
0.706 0.294 0.000
R22.2 Localised swelling, mass and lump, trunk
0.705 0.295 0.000
S00.5 Superficial injury of lip and oral cavity
0.705 0.295 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.705 0.295 0.000
S26 Injury of heart
0.705 0.295 0.000
S25 Injury of blood vessels of thorax
0.705 0.295 0.000
S24 Injury of nerves and spinal cord at thorax level
0.705 0.295 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.705 0.295 0.000
S21 Open wound of thorax
0.705 0.295 0.000
G81.9 Hemiplegia, unspecified
0.705 0.295 0.000
C18.8 Overlapping lesion of colon
0.704 0.295 0.000
C18.1 Appendix
0.704 0.295 0.000
E27.2 Addisonian crisis
0.704 0.296 0.000
B95-B98 Bacterial, viral and other infectious agents
0.703 0.297 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.703 0.297 0.000
C71 Malignant neoplasm of brain
0.703 0.297 0.000
R56.8 Other and unspecified convulsions
0.702 0.298 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.702 0.298 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.702 0.298 0.000
S22.5 Flail chest
0.702 0.298 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.701 0.299 0.000
E20 Hypoparathyroidism
0.700 0.299 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.700 0.299 0.000
I95.8 Other hypotension
0.700 0.300 0.000
I95.0 Idiopathic hypotension
0.700 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.699 0.301 0.000
I69.3 Sequelae of cerebral infarction
0.698 0.302 0.000
B49 Unspecified mycosis
0.698 0.302 0.000
H92 Otalgia and effusion of ear
0.697 0.303 0.000
S32.4 Fracture of acetabulum
0.697 0.303 0.000
S82.4 Fracture of fibula alone
0.697 0.303 0.000
B44 Aspergillosis
0.696 0.303 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.696 0.303 0.000
F33.8 Other recurrent depressive disorders
0.696 0.304 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.696 0.304 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.696 0.304 0.000
O03 Spontaneous abortion
0.696 0.304 0.000
S02.6 Fracture of mandible
0.696 0.304 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.694 0.306 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.694 0.306 0.000
I67.5 Moyamoya disease
0.694 0.306 0.000
I67.4 Hypertensive encephalopathy
0.694 0.306 0.000
I67.3 Progressive vascular leukoencephalopathy
0.694 0.306 0.000
S88 Traumatic amputation of lower leg
0.694 0.306 0.000
S87 Crushing injury of lower leg
0.694 0.306 0.000
S86 Injury of muscle and tendon at lower leg level
0.694 0.306 0.000
S85 Injury of blood vessels at lower leg level
0.694 0.306 0.000
S84 Injury of nerves at lower leg level
0.694 0.306 0.000
R52 Pain, not elsewhere classified
0.693 0.307 0.000
G82.5 Tetraplegia, unspecified
0.693 0.307 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.693 0.307 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.692 0.308 0.000
E26 Hyperaldosteronism
0.692 0.308 0.000
N87 Dysplasia of cervix uteri
0.691 0.309 0.000
B25-B34 Other viral diseases
0.691 0.309 0.000
I67.2 Cerebral atherosclerosis
0.691 0.309 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.691 0.309 0.000
C67 Malignant neoplasm of bladder
0.691 0.309 0.000
C21 Malignant neoplasm of anus and anal canal
0.690 0.310 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.690 0.310 0.000
B50-B64 Protozoal diseases
0.690 0.310 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.690 0.310 0.000
A75-A79 Rickettsioses
0.690 0.310 0.000
A70-A74 Other diseases caused by chlamydiae
0.690 0.310 0.000
A65-A69 Other spirochaetal diseases
0.690 0.310 0.000
A20-A28 Certain zoonotic bacterial diseases
0.690 0.310 0.000
A15-A19 Tuberculosis
0.690 0.310 0.000
S01.3 Open wound of ear
0.689 0.311 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.689 0.311 0.000
B37.1 Pulmonary candidiasis
0.689 0.311 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.688 0.312 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.688 0.312 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.688 0.312 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.688 0.312 0.000
G92 Toxic encephalopathy
0.688 0.312 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.688 0.312 0.000
R57 Shock, not elsewhere classified
0.687 0.313 0.000
S27.9 Injury of unspecified intrathoracic organ
0.687 0.313 0.000
S27.7 Multiple injuries of intrathoracic organs
0.687 0.313 0.000
S27.6 Injury of pleura
0.687 0.313 0.000
S27.5 Injury of thoracic trachea
0.687 0.313 0.000
S27.4 Injury of bronchus
0.687 0.313 0.000
L60-L75 Disorders of skin appendages
0.687 0.313 0.000
E27.1 Primary adrenocortical insufficiency
0.685 0.314 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.685 0.314 0.000
O85-O92 Complications predominantly related to the puerperium
0.685 0.315 0.000
I63.9 Cerebral infarction, unspecified
0.683 0.317 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.683 0.317 0.000
E40-E46 Malnutrition
0.682 0.318 0.000
B80 Enterobiasis
0.682 0.318 0.000
S06.8 Other intracranial injuries
0.681 0.318 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.682 0.318 0.000
G71.1 Myotonic disorders
0.681 0.319 0.000
F60-F69 Disorders of adult personality and behaviour
0.681 0.319 0.000
G41 Status epilepticus
0.680 0.319 0.000
B99-B99 Other infectious diseases
0.680 0.320 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.680 0.320 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.680 0.320 0.000
E06 Thyroiditis
0.680 0.320 0.000
C17.9 Small intestine, unspecified
0.679 0.321 0.000
G93.0 Cerebral cysts
0.679 0.321 0.000
I63.8 Other cerebral infarction
0.678 0.322 0.000
S01.0 Open wound of scalp
0.678 0.322 0.000
D73 Diseases of spleen
0.677 0.323 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.677 0.323 0.000
D00-D09 In situ neoplasms
0.677 0.323 0.000
R47-R49 Symptoms and signs involving speech and voice
0.677 0.323 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.676 0.324 0.000
E07 Other disorders of thyroid
0.676 0.324 0.000
G91.9 Hydrocephalus, unspecified
0.675 0.325 0.000
C81 Hodgkin's disease
0.675 0.325 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.675 0.325 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.673 0.326 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.673 0.327 0.000
R61 Hyperhidrosis
0.673 0.327 0.000
F99 Mental disorder, not otherwise specified
0.673 0.327 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.672 0.328 0.000
E32 Diseases of thymus
0.672 0.328 0.000
E31 Polyglandular dysfunction
0.672 0.328 0.000
E30 Disorders of puberty, not elsewhere classified
0.672 0.328 0.000
E25 Adrenogenital disorders
0.672 0.328 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.672 0.328 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.672 0.328 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.672 0.328 0.000
S70-S79 Injuries to the hip and thigh
0.671 0.328 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.671 0.329 0.000
H55-H59 Other disorders of eye and adnexa
0.671 0.329 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.671 0.329 0.000
I67.1 Cerebral aneurysm, nonruptured
0.671 0.329 0.000
I22 Subsequent myocardial infarction
0.670 0.330 0.000
D50-D53 Nutritional anaemias
0.670 0.330 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.670 0.330 0.000
G03 Meningitis due to other and unspecified causes
0.669 0.331 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.669 0.331 0.000
G47.4 Narcolepsy and cataplexy
0.669 0.331 0.000
G47.2 Disorders of the sleep-wake schedule
0.669 0.331 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.668 0.332 0.000
S83.2 Tear of meniscus, current
0.668 0.332 0.000
E24 Cushing's syndrome
0.667 0.333 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.667 0.333 0.000
N94.1 Dyspareunia
0.667 0.333 0.000
E34 Other endocrine disorders
0.667 0.333 0.000
S01.2 Open wound of nose
0.667 0.333 0.000
O48 Prolonged pregnancy
0.666 0.334 0.000
G12.2 Motor neuron disease
0.666 0.334 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.665 0.334 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.665 0.335 0.000
R62 Lack of expected normal physiological development
0.665 0.335 0.000
R64 Cachexia
0.665 0.335 0.000
S80.0 Contusion of knee
0.665 0.335 0.000
G72.0 Drug-induced myopathy
0.664 0.336 0.000
I95.2 Hypotension due to drugs
0.664 0.336 0.000
N80.0 Endometriosis of uterus
0.664 0.336 0.000
B37.4 Candidiasis of other urogenital sites
0.663 0.337 0.000
H92.1 Otorrhoea
0.663 0.337 0.000
C88 Malignant immunoproliferative diseases
0.662 0.338 0.000
I20 Angina pectoris
0.662 0.338 0.000
A40 Streptococcal septicaemia
0.662 0.338 0.000
R50.8 Other specified fever
0.661 0.339 0.000
B35 Dermatophytosis
0.661 0.339 0.000
C16 Malignant neoplasm of stomach
0.660 0.339 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.660 0.339 0.000
L60 Nail disorders
0.660 0.340 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.660 0.340 0.000
C51 Malignant neoplasm of vulva
0.660 0.340 0.000
C58 Malignant neoplasm of placenta
0.660 0.340 0.000
C52 Malignant neoplasm of vagina
0.660 0.340 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.659 0.340 0.000
S09 Other and unspecified injuries of head
0.659 0.341 0.000
F80 Specific developmental disorders of speech and language
0.658 0.341 0.000
S90 Superficial injury of ankle and foot
0.658 0.342 0.000
S00.4 Superficial injury of ear
0.657 0.343 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.657 0.343 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.657 0.343 0.000
S30.2 Contusion of external genital organs
0.657 0.343 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.655 0.344 0.000
S82.3 Fracture of lower end of tibia
0.655 0.345 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.655 0.345 0.000
R21 Rash and other nonspecific skin eruption
0.655 0.345 0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)
0.654 0.346 0.000
O03.4 Incomplete, without complication
0.654 0.346 0.000
H40.2 Primary angle-closure glaucoma
0.654 0.346 0.000
B48 Other mycoses, not elsewhere classified
0.654 0.346 0.000
B47 Mycetoma
0.654 0.346 0.000
B46 Zygomycosis
0.654 0.346 0.000
B45 Cryptococcosis
0.654 0.346 0.000
B43 Chromomycosis and phaeomycotic abscess
0.654 0.346 0.000
B42 Sporotrichosis
0.654 0.346 0.000
B41 Paracoccidioidomycosis
0.654 0.346 0.000
B40 Blastomycosis
0.654 0.346 0.000
B39 Histoplasmosis
0.654 0.346 0.000
B38 Coccidioidomycosis
0.654 0.346 0.000
B36 Other superficial mycoses
0.654 0.346 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.653 0.347 0.000
C69 Malignant neoplasm of eye and adnexa
0.652 0.348 0.000
G11 Hereditary ataxia
0.651 0.349 0.000
E05.9 Thyrotoxicosis, unspecified
0.651 0.349 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.651 0.349 0.000
N91 Absent, scanty and rare menstruation
0.650 0.349 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.650 0.350 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.649 0.351 0.000
S02.2 Fracture of nasal bones
0.649 0.351 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.649 0.351 0.000
E00 Congenital iodine-deficiency syndrome
0.649 0.351 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.649 0.351 0.000
S02.3 Fracture of orbital floor
0.649 0.351 0.000
R50.2 Drug-induced fever
0.649 0.351 0.000
R50.1 Persistent fever
0.649 0.351 0.000
S82.81 Fractures of other parts of lower leg (open)
0.648 0.352 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.648 0.352 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.648 0.352 0.000
C95 Leukaemia of unspecified cell type
0.648 0.352 0.000
C94 Other leukaemias of specified cell type
0.648 0.352 0.000
C93 Monocytic leukaemia
0.648 0.352 0.000
C86 Other specified types of T/NK-cell lymphoma
0.648 0.352 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.648 0.352 0.000
S82.10 Fracture of upper end of tibia (closed)
0.647 0.353 0.000
N92.4 Excessive bleeding in the premenopausal period
0.647 0.353 0.000
Chapter XI Diseases of the digestive system
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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