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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs201564772
log Bayes Factor = 17.1704
Chromosome 21   position 17,774,632  (GRCh37) Explore rs201564772 on Ensembl!
Variant rs201564772 is part of Cluster X0161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
R50-R69 General symptoms and signs
0.994 0.006 0.000
Chapter XI Diseases of the digestive system
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.991 0.009 0.000
F30-F39 Mood [affective] disorders
0.991 0.009 0.000
R63 Symptoms and signs concerning food and fluid intake
0.990 0.010 0.000
D10-D36 Benign neoplasms
0.989 0.011 0.000
K70-K77 Diseases of liver
0.988 0.012 0.000
F32 Depressive episode
0.986 0.014 0.000
R63.4 Abnormal weight loss
0.985 0.015 0.000
S00-S09 Injuries to the head
0.983 0.017 0.000
F32.9 Depressive episode, unspecified
0.982 0.018 0.000
K70 Alcoholic liver disease
0.977 0.023 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.976 0.024 0.000
N30-N39 Other diseases of urinary system
0.976 0.024 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.975 0.025 0.000
W00-W19 Falls
0.969 0.031 0.000
M20-M25 Other joint disorders
0.968 0.032 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.966 0.034 0.000
Chapter X Diseases of the respiratory system
0.965 0.035 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.960 0.040 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.954 0.046 0.000
D22 Melanocytic naevi
0.950 0.050 0.000
S00 Superficial injury of head
0.947 0.053 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.939 0.061 0.000
M45-M49 Spondylopathies
0.936 0.064 0.000
M20 Acquired deformities of fingers and toes
0.935 0.065 0.000
K70.9 Alcoholic liver disease, unspecified
0.934 0.066 0.000
W19 Unspecified fall
0.930 0.070 0.000
N30 Cystitis
0.926 0.074 0.000
R52 Pain, not elsewhere classified
0.923 0.077 0.000
N17-N19 Renal failure
0.909 0.091 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.908 0.092 0.000
S00.8 Superficial injury of other parts of head
0.902 0.098 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.897 0.103 0.000
J40-J47 Chronic lower respiratory diseases
0.897 0.103 0.000
M50-M54 Other dorsopathies
0.893 0.107 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.893 0.107 0.000
S60-S69 Injuries to the wrist and hand
0.891 0.109 0.000
M70-M79 Other soft tissue disorders
0.889 0.111 0.000
M47 Spondylosis
0.886 0.114 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.886 0.114 0.000
N25-N29 Other disorders of kidney and ureter
0.883 0.117 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.880 0.120 0.000
R59 Enlarged lymph nodes
0.879 0.121 0.000
M80-M85 Disorders of bone density and structure
0.879 0.121 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.877 0.123 0.000
K86 Other diseases of pancreas
0.876 0.124 0.000
K76 Other diseases of liver
0.875 0.125 0.000
S40-S49 Injuries to the shoulder and upper arm
0.874 0.126 0.000
O60-O75 Complications of labour and delivery
0.874 0.126 0.000
D23 Other benign neoplasms of skin
0.873 0.127 0.000
M15-M19 Arthrosis
0.873 0.127 0.000
S80-S89 Injuries to the knee and lower leg
0.871 0.129 0.000
W19.9 Unspecified place
0.870 0.130 0.000
K70.3 Alcoholic cirrhosis of liver
0.870 0.130 0.000
C64-C68 Malignant neoplasms of urinary tract
0.869 0.131 0.000
L90 Atrophic disorders of skin
0.864 0.136 0.000
D22.5 Melanocytic naevi of trunk
0.864 0.136 0.000
M20.1 Hallux valgus (acquired)
0.859 0.141 0.000
J44 Other chronic obstructive pulmonary disease
0.858 0.142 0.000
D18 Haemangioma and lymphangioma, any site
0.856 0.144 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.855 0.145 0.000
R63.0 Anorexia
0.852 0.148 0.000
D17 Benign lipomatous neoplasm
0.852 0.148 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.851 0.149 0.000
Chapter VIII Diseases of the ear and mastoid process
0.849 0.151 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.847 0.153 0.000
M47.8 Other spondylosis
0.847 0.153 0.000
K83 Other diseases of biliary tract
0.846 0.154 0.000
K70.1 Alcoholic hepatitis
0.843 0.157 0.000
F10.2 Dependence syndrome
0.841 0.159 0.000
Chapter VI Diseases of the nervous system
0.841 0.159 0.000
D36 Benign neoplasm of other and unspecified sites
0.839 0.161 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.834 0.166 0.000
K72 Hepatic failure, not elsewhere classified
0.828 0.172 0.000
S01 Open wound of head
0.827 0.173 0.000
M75 Shoulder lesions
0.824 0.176 0.000
N10-N16 Renal tubulo-interstitial diseases
0.823 0.177 0.000
R52.1 Chronic intractable pain
0.823 0.177 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.822 0.178 0.000
W13 Fall from, out of or through building or structure
0.821 0.179 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.818 0.182 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.817 0.182 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.817 0.183 0.000
M05-M14 Inflammatory polyarthropathies
0.815 0.185 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.815 0.185 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.814 0.186 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.811 0.189 0.000
N30.2 Other chronic cystitis
0.811 0.189 0.000
K50-K52 Noninfective enteritis and colitis
0.807 0.193 0.000
R53 Malaise and fatigue
0.806 0.194 0.000
S20-S29 Injuries to the thorax
0.805 0.194 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.805 0.195 0.000
V20-V29 Motorcycle rider injured in transport accident
0.804 0.196 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.804 0.196 0.000
M25 Other joint disorders, not elsewhere classified
0.803 0.197 0.000
R06 Abnormalities of breathing
0.802 0.198 0.000
M19 Other arthrosis
0.801 0.199 0.000
S06 Intracranial injury
0.801 0.199 0.000
J90-J94 Other diseases of pleura
0.800 0.200 0.000
L90.5 Scar conditions and fibrosis of skin
0.799 0.201 0.000
W19.4 Street and highway
0.797 0.203 0.000
N19 Unspecified renal failure
0.796 0.204 0.000
S00.0 Superficial injury of scalp
0.792 0.208 0.000
F10.3 Withdrawal state
0.790 0.209 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.788 0.212 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.788 0.212 0.000
R52.2 Other chronic pain
0.788 0.212 0.000
D26 Other benign neoplasms of uterus
0.788 0.212 0.000
F17.1 Harmful use
0.788 0.212 0.000
D00-D09 In situ neoplasms
0.786 0.214 0.000
C15-C26 Malignant neoplasms of digestive organs
0.786 0.214 0.000
X50-X57 Overexertion, travel and privation
0.785 0.214 0.000
N35 Urethral stricture
0.784 0.216 0.000
J00-J06 Acute upper respiratory infections
0.784 0.216 0.000
F10.0 Acute intoxication
0.782 0.217 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.782 0.218 0.000
M20.4 Other hammer toe(s) (acquired)
0.778 0.222 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.773 0.227 0.000
K82 Other diseases of gallbladder
0.773 0.227 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.773 0.227 0.000
K80 Cholelithiasis
0.773 0.227 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.772 0.228 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.772 0.228 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.772 0.228 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.771 0.229 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.771 0.229 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.767 0.233 0.000
Chapter I Certain infectious and parasitic diseases
0.767 0.233 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.767 0.233 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.766 0.234 0.000
N32 Other disorders of bladder
0.765 0.235 0.000
M54 Dorsalgia
0.765 0.235 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.764 0.236 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.764 0.236 0.000
M21 Other acquired deformities of limbs
0.763 0.237 0.000
D18.0 Haemangioma, any site
0.761 0.239 0.000
R00 Abnormalities of heart beat
0.760 0.240 0.000
S40 Superficial injury of shoulder and upper arm
0.759 0.241 0.000
L20-L30 Dermatitis and eczema
0.759 0.241 0.000
N30.0 Acute cystitis
0.758 0.242 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.758 0.242 0.000
D23.7 Skin of lower limb, including hip
0.758 0.242 0.000
N39 Other disorders of urinary system
0.756 0.244 0.000
M19.9 Arthrosis, unspecified
0.756 0.244 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.755 0.245 0.000
D27 Benign neoplasm of ovary
0.754 0.245 0.000
L85 Other epidermal thickening
0.753 0.247 0.000
M31 Other necrotising vasculopathies
0.753 0.247 0.000
M47.89 Other spondylosis (Site unspecified)
0.752 0.248 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.752 0.248 0.000
O48 Prolonged pregnancy
0.752 0.248 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.751 0.249 0.000
N30.1 Interstitial cystitis (chronic)
0.751 0.249 0.000
K86.1 Other chronic pancreatitis
0.750 0.250 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.748 0.252 0.000
D50-D53 Nutritional anaemias
0.748 0.252 0.000
R59.0 Localised enlarged lymph nodes
0.748 0.252 0.000
M20.5 Other deformities of toe(s) (acquired)
0.747 0.253 0.000
L89 Decubitus ulcer
0.747 0.253 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.746 0.254 0.000
K65-K67 Diseases of peritoneum
0.745 0.255 0.000
L50-L54 Urticaria and erythema
0.745 0.255 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.743 0.257 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.743 0.257 0.000
L91 Hypertrophic disorders of skin
0.741 0.259 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.740 0.259 0.000
R06.0 Dyspnoea
0.740 0.260 0.000
J40 Bronchitis, not specified as acute or chronic
0.740 0.260 0.000
Chapter VII Diseases of the eye and adnexa
0.738 0.262 0.000
M20.3 Other deformity of hallux (acquired)
0.737 0.263 0.000
N28.1 Cyst of kidney, acquired
0.737 0.263 0.000
K76.8 Other specified diseases of liver
0.736 0.264 0.000
K85 Acute pancreatitis
0.736 0.264 0.000
J20-J22 Other acute lower respiratory infections
0.735 0.265 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.734 0.266 0.000
N30.9 Cystitis, unspecified
0.734 0.266 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.732 0.268 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.732 0.268 0.000
F33 Recurrent depressive disorder
0.732 0.268 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.732 0.268 0.000
R69 Unknown and unspecified causes of morbidity
0.731 0.269 0.000
M51 Other intervertebral disk disorders
0.731 0.269 0.000
S09 Other and unspecified injuries of head
0.728 0.272 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.728 0.272 0.000
J95-J99 Other diseases of the respiratory system
0.727 0.273 0.000
N17 Acute renal failure
0.727 0.273 0.000
R02 Gangrene, not elsewhere classified
0.727 0.273 0.000
W20-W49 Exposure to inanimate mechanical forces
0.725 0.274 0.000
S02 Fracture of skull and facial bones
0.724 0.276 0.000
M81 Osteoporosis without pathological fracture
0.724 0.276 0.000
R59.1 Generalised enlarged lymph nodes
0.724 0.276 0.000
M86-M90 Other osteopathies
0.722 0.278 0.000
F10.1 Harmful use
0.722 0.278 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.722 0.278 0.000
M19.94 Arthrosis, unspecified (Hand)
0.722 0.278 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.722 0.278 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.721 0.279 0.000
N18 Chronic renal failure
0.720 0.280 0.000
N36 Other disorders of urethra
0.719 0.280 0.000
M24 Other specific joint derangements
0.719 0.281 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.718 0.282 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.718 0.282 0.000
O72 Postpartum haemorrhage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
L40-L45 Papulosquamous disorders
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
D23.4 Skin of scalp and neck
0.717 0.283 0.000
R68 Other general symptoms and signs
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.716 0.284 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.716 0.284 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
Chapter XXII Codes for special purposes
0.716 0.284 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.716 0.284 0.000
W13.9 Unspecified place
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.715 0.284 0.000
K83.8 Other specified diseases of biliary tract
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.714 0.286 0.000
M25.7 Osteophyte
0.714 0.286 0.000
K72.9 Hepatic failure, unspecified
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.712 0.288 0.000
R62 Lack of expected normal physiological development
0.712 0.288 0.000
R57 Shock, not elsewhere classified
0.712 0.288 0.000
R64 Cachexia
0.712 0.288 0.000
R58 Haemorrhage, not elsewhere classified
0.712 0.288 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.712 0.288 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.712 0.288 0.000
Y57 Other and unspecified drugs and medicaments
0.712 0.288 0.000
M16 Coxarthrosis [arthrosis of hip]
0.711 0.289 0.000
S61 Open wound of wrist and hand
0.711 0.289 0.000
F38 Other mood [affective] disorders
0.710 0.289 0.000
F34 Persistent mood [affective] disorders
0.710 0.289 0.000
F30 Manic episode
0.710 0.289 0.000
F39 Unspecified mood [affective] disorder
0.710 0.289 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.710 0.290 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.710 0.290 0.000
R63.5 Abnormal weight gain
0.710 0.290 0.000
R63.3 Feeding difficulties and mismanagement
0.710 0.290 0.000
R63.2 Polyphagia
0.710 0.290 0.000
R63.1 Polydipsia
0.710 0.290 0.000
D31 Benign neoplasm of eye and adnexa
0.709 0.291 0.000
D30 Benign neoplasm of urinary organs
0.709 0.291 0.000
D29 Benign neoplasm of male genital organs
0.709 0.291 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.709 0.291 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.709 0.291 0.000
D19 Benign neoplasm of mesothelial tissue
0.709 0.291 0.000
D16 Benign neoplasm of bone and articular cartilage
0.709 0.291 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.709 0.291 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.709 0.291 0.000
D11 Benign neoplasm of major salivary glands
0.709 0.291 0.000
D10 Benign neoplasm of mouth and pharynx
0.709 0.291 0.000
D34 Benign neoplasm of thyroid gland
0.709 0.291 0.000
K77 Liver disorders in diseases classified elsewhere
0.708 0.292 0.000
K75 Other inflammatory liver diseases
0.708 0.292 0.000
K73 Chronic hepatitis, not elsewhere classified
0.708 0.292 0.000
K71 Toxic liver disease
0.708 0.292 0.000
K50 Crohn's disease [regional enteritis]
0.708 0.292 0.000
O70 Perineal laceration during delivery
0.708 0.292 0.000
R47-R49 Symptoms and signs involving speech and voice
0.707 0.293 0.000
S90-S99 Injuries to the ankle and foot
0.707 0.293 0.000
F32.8 Other depressive episodes
0.707 0.293 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.707 0.293 0.000
F32.1 Moderate depressive episode
0.707 0.293 0.000
F32.0 Mild depressive episode
0.707 0.293 0.000
M22 Disorders of patella
0.707 0.293 0.000
N60-N64 Disorders of breast
0.707 0.293 0.000
T66-T78 Other and unspecified effects of external causes
0.706 0.294 0.000
C67 Malignant neoplasm of bladder
0.706 0.294 0.000
K76.9 Liver disease, unspecified
0.706 0.294 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.706 0.294 0.000
S08 Traumatic amputation of part of head
0.705 0.295 0.000
S07 Crushing injury of head
0.705 0.295 0.000
S05 Injury of eye and orbit
0.705 0.295 0.000
S04 Injury of cranial nerves
0.705 0.295 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.705 0.295 0.000
N39.3 Stress incontinence
0.705 0.295 0.000
O80-O84 Delivery
0.704 0.296 0.000
S70-S79 Injuries to the hip and thigh
0.704 0.296 0.000
K76.6 Portal hypertension
0.704 0.296 0.000
D36.7 Other specified sites
0.703 0.297 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.703 0.297 0.000
R61 Hyperhidrosis
0.703 0.297 0.000
S01.8 Open wound of other parts of head
0.702 0.298 0.000
D23.6 Skin of upper limb, including shoulder
0.702 0.298 0.000
M47.86 Other spondylosis (Lumbar region)
0.701 0.299 0.000
K70.4 Alcoholic hepatic failure
0.700 0.300 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.700 0.300 0.000
K70.0 Alcoholic fatty liver
0.700 0.300 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.700 0.300 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.700 0.300 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.700 0.300 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.700 0.300 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.700 0.300 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.700 0.300 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.700 0.300 0.000
F11 Mental and behavioural disorders due to use of opioids
0.700 0.300 0.000
R29.6 Tendency to fall, not elsewhere classified
0.700 0.300 0.000
N37 Urethral disorders in diseases classified elsewhere
0.700 0.300 0.000
N34 Urethritis and urethral syndrome
0.700 0.300 0.000
N33 Bladder disorders in diseases classified elsewhere
0.700 0.300 0.000
M46 Other inflammatory spondylopathies
0.699 0.300 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.699 0.300 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.699 0.301 0.000
L10-L14 Bullous disorders
0.699 0.301 0.000
R51 Headache
0.698 0.302 0.000
M80 Osteoporosis with pathological fracture
0.698 0.302 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.697 0.303 0.000
N32.3 Diverticulum of bladder
0.697 0.303 0.000
D35.2 Pituitary gland
0.696 0.304 0.000
W19.2 School, other institution and public administrative area
0.695 0.305 0.000
K86.9 Disease of pancreas, unspecified
0.695 0.305 0.000
W18 Other fall on same level
0.694 0.305 0.000
W17 Other fall from one level to another
0.694 0.305 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.694 0.305 0.000
W15 Fall from cliff
0.694 0.305 0.000
W14 Fall from tree
0.694 0.305 0.000
W12 Fall on and from scaffolding
0.694 0.305 0.000
W11 Fall on and from ladder
0.694 0.305 0.000
W10 Fall on and from stairs and steps
0.694 0.305 0.000
W09 Fall involving playground equipment
0.694 0.305 0.000
W08 Fall involving other furniture
0.694 0.305 0.000
W07 Fall involving chair
0.694 0.305 0.000
W06 Fall involving bed
0.694 0.305 0.000
W05 Fall involving wheelchair
0.694 0.305 0.000
W04 Fall while being carried or supported by other persons
0.694 0.305 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.694 0.305 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.694 0.305 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.694 0.305 0.000
W00 Fall on same level involving ice and snow
0.694 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M34 Systemic sclerosis
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M32 Systemic lupus erythematosus
0.694 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.306 0.000
R04 Haemorrhage from respiratory passages
0.694 0.306 0.000
M75.5 Bursitis of shoulder
0.694 0.306 0.000
J60-J70 Lung diseases due to external agents
0.693 0.307 0.000
O00-O08 Pregnancy with abortive outcome
0.693 0.307 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.693 0.307 0.000
O85-O92 Complications predominantly related to the puerperium
0.692 0.308 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.691 0.309 0.000
V10-V19 Pedal cyclist injured in transport accident
0.691 0.309 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.691 0.309 0.000
R27 Other lack of coordination
0.690 0.309 0.000
J81 Pulmonary oedema
0.690 0.310 0.000
M40-M43 Deforming dorsopathies
0.690 0.310 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.690 0.310 0.000
M85 Other disorders of bone density and structure
0.689 0.311 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.688 0.311 0.000
K83.1 Obstruction of bile duct
0.688 0.312 0.000
K74 Fibrosis and cirrhosis of liver
0.687 0.312 0.000
S80 Superficial injury of lower leg
0.686 0.314 0.000
S00.9 Superficial injury of head, part unspecified
0.685 0.315 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.684 0.316 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.684 0.316 0.000
L94 Other localised connective tissue disorders
0.684 0.316 0.000
L93 Lupus erythematosus
0.684 0.316 0.000
L87 Transepidermal elimination disorders
0.684 0.316 0.000
L88 Pyoderma gangrenosum
0.684 0.316 0.000
L86 Keratoderma in diseases classified elsewhere
0.684 0.316 0.000
L83 Acanthosis nigricans
0.684 0.316 0.000
L80 Vitiligo
0.684 0.316 0.000
Y52 Agents primarily affecting the cardiovascular system
0.684 0.316 0.000
K86.2 Cyst of pancreas
0.683 0.317 0.000
S82 Fracture of lower leg, including ankle
0.682 0.318 0.000
D22.9 Melanocytic naevi, unspecified
0.681 0.318 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.681 0.318 0.000
D22.0 Melanocytic naevi of lip
0.681 0.318 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.681 0.318 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.680 0.319 0.000
S68 Traumatic amputation of wrist and hand
0.680 0.320 0.000
R25 Abnormal involuntary movements
0.680 0.320 0.000
S00.7 Multiple superficial injuries of head
0.679 0.321 0.000
S00.5 Superficial injury of lip and oral cavity
0.679 0.321 0.000
S00.4 Superficial injury of ear
0.679 0.321 0.000
S00.3 Superficial injury of nose
0.679 0.321 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.679 0.321 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.678 0.321 0.000
H90-H95 Other disorders of ear
0.678 0.322 0.000
S89 Other and unspecified injuries of lower leg
0.677 0.323 0.000
J46 Status asthmaticus
0.677 0.323 0.000
O62 Abnormalities of forces of labour
0.676 0.324 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.676 0.324 0.000
L84 Corns and callosities
0.675 0.325 0.000
M45 Ankylosing spondylitis
0.675 0.325 0.000
S00.1 Contusion of eyelid and periocular area
0.675 0.325 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.674 0.326 0.000
R50 Fever of unknown origin
0.674 0.326 0.000
N30.8 Other cystitis
0.673 0.327 0.000
F10.9 Unspecified mental and behavioural disorder
0.673 0.327 0.000
F10.8 Other mental and behavioural disorders
0.673 0.327 0.000
F10.7 Residual and late-onset psychotic disorder
0.673 0.327 0.000
F10.6 Amnesic syndrome
0.673 0.327 0.000
F10.5 Psychotic disorder
0.673 0.327 0.000
F10.4 Withdrawal state with delirium
0.673 0.327 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.673 0.327 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.673 0.327 0.000
D32 Benign neoplasm of meninges
0.672 0.327 0.000
N28.8 Other specified disorders of kidney and ureter
0.672 0.328 0.000
M49 Spondylopathies in diseases classified elsewhere
0.671 0.328 0.000
M20.0 Deformity of finger(s)
0.670 0.330 0.000
O41 Other disorders of amniotic fluid and membranes
0.670 0.330 0.000
K86.8 Other specified diseases of pancreas
0.669 0.331 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.669 0.331 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.668 0.332 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.668 0.332 0.000
M20.2 Hallux rigidus
0.668 0.332 0.000
C43 Malignant melanoma of skin
0.668 0.332 0.000
S81 Open wound of lower leg
0.668 0.332 0.000
M71 Other bursopathies
0.668 0.332 0.000
O36 Maternal care for other known or suspected foetal problems
0.667 0.332 0.000
M65-M68 Disorders of synovium and tendon
0.667 0.333 0.000
W19.8 Other specified place
0.667 0.333 0.000
W19.5 Trade and service area
0.667 0.333 0.000
W19.0 Home
0.667 0.333 0.000
W19.7 Farm
0.667 0.333 0.000
W19.6 Industrial and construction area
0.667 0.333 0.000
W19.3 Sports and athletics area
0.667 0.333 0.000
W19.1 Residential institution
0.667 0.333 0.000
R52.9 Pain, unspecified
0.667 0.333 0.000
Y42.5 Other oestrogens and progestogens
0.666 0.334 0.000
J43 Emphysema
0.666 0.334 0.000
M25.4 Effusion of joint
0.666 0.334 0.000
M48 Other spondylopathies
0.666 0.334 0.000
C15 Malignant neoplasm of oesophagus
0.666 0.334 0.000
H80-H83 Diseases of inner ear
0.666 0.334 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.665 0.334 0.000
Chapter IX Diseases of the circulatory system
0.665 0.335 0.000
M75.4 Impingement syndrome of shoulder
0.664 0.336 0.000
N30.4 Irradiation cystitis
0.664 0.336 0.000
N30.3 Trigonitis
0.664 0.336 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.664 0.336 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.664 0.336 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.663 0.337 0.000
Y83.8 Other surgical procedures
0.663 0.337 0.000
T86 Failure and rejection of transplanted organs and tissues
0.663 0.337 0.000
G40-G47 Episodic and paroxysmal disorders
0.662 0.338 0.000
R52.0 Acute pain
0.662 0.338 0.000
J90 Pleural effusion, not elsewhere classified
0.661 0.339 0.000
M50 Cervical disk disorders
0.659 0.341 0.000
M75.1 Rotator cuff syndrome
0.659 0.341 0.000
G51 Facial nerve disorders
0.659 0.341 0.000
N13 Obstructive and reflux uropathy
0.659 0.341 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.658 0.342 0.000
R60 Oedema, not elsewhere classified
0.656 0.344 0.000
J02 Acute pharyngitis
0.656 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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