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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs204993
log Bayes Factor = 249.805
Chromosome 6   position 32,155,581  (GRCh37) Explore rs204993 on Ensembl!
Variant rs204993 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
0.999 0.001 0.000
D64 Other anaemias
0.999 0.001 0.000
D60-D64 Aplastic and other anaemias
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
E10.1 With ketoacidosis
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.998 0.002 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.997 0.003 0.000
E14.9 Without complications
0.996 0.004 0.000
D00-D09 In situ neoplasms
0.995 0.005 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.994 0.006 0.000
D50-D53 Nutritional anaemias
0.992 0.008 0.000
E16 Other disorders of pancreatic internal secretion
0.991 0.009 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.986 0.014 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.985 0.015 0.000
E16.2 Hypoglycaemia, unspecified
0.984 0.016 0.000
E11.3 With ophthalmic complications
0.984 0.016 0.000
E14.3 With ophthalmic complications
0.982 0.018 0.000
K90 Intestinal malabsorption
0.980 0.020 0.000
D07.1 Vulva
0.980 0.020 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.979 0.021 0.000
C15 Malignant neoplasm of oesophagus
0.979 0.021 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.973 0.027 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.973 0.027 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.972 0.028 0.000
E11.1 With ketoacidosis
0.971 0.029 0.000
G35 Multiple sclerosis
0.000 0.030 0.970
Chapter VI Diseases of the nervous system
0.970 0.030 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.967 0.033 0.000
G51 Facial nerve disorders
0.966 0.034 0.000
I74 Arterial embolism and thrombosis
0.965 0.035 0.000
Chapter IX Diseases of the circulatory system
0.965 0.035 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.964 0.036 0.000
D51 Vitamin B12 deficiency anaemia
0.960 0.040 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.959 0.041 0.000
G51.0 Bell's palsy
0.957 0.043 0.000
L40.5 Arthropathic psoriasis
0.954 0.046 0.000
C85.1 B-cell lymphoma, unspecified
0.953 0.047 0.000
Q50-Q56 Congenital malformations of genital organs
0.952 0.048 0.000
C91 Lymphoid leukaemia
0.952 0.048 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.025 0.049 0.926
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.950 0.050 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.947 0.053 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.944 0.056 0.000
I73 Other peripheral vascular diseases
0.944 0.056 0.000
L40.0 Psoriasis vulgaris
0.938 0.062 0.000
K75 Other inflammatory liver diseases
0.937 0.063 0.000
K90-K93 Other diseases of the digestive system
0.933 0.067 0.000
K70-K77 Diseases of liver
0.932 0.068 0.000
E20-E35 Disorders of other endocrine glands
0.931 0.069 0.000
D04 Carcinoma in situ of skin
0.931 0.069 0.000
Chapter XI Diseases of the digestive system
0.930 0.070 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.070 0.930
K75.8 Other specified inflammatory liver diseases
0.928 0.072 0.000
D50 Iron deficiency anaemia
0.928 0.072 0.000
I73.9 Peripheral vascular disease, unspecified
0.926 0.074 0.000
Q43 Other congenital malformations of intestine
0.923 0.077 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.922 0.078 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.921 0.079 0.000
C21 Malignant neoplasm of anus and anal canal
0.919 0.081 0.000
G37 Other demyelinating diseases of central nervous system
0.004 0.085 0.910
D50.9 Iron deficiency anaemia, unspecified
0.914 0.086 0.000
I05-I09 Chronic rheumatic heart diseases
0.913 0.087 0.000
C18 Malignant neoplasm of colon
0.912 0.088 0.000
J45 Asthma
0.911 0.089 0.000
K75.4 Autoimmune hepatitis
0.911 0.089 0.000
Q54 Hypospadias
0.909 0.091 0.000
L10-L14 Bullous disorders
0.908 0.092 0.000
C15.4 Middle third of oesophagus
0.906 0.094 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.904 0.096 0.000
G51.9 Disorder of facial nerve, unspecified
0.898 0.102 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.898 0.102 0.000
K73 Chronic hepatitis, not elsewhere classified
0.898 0.102 0.000
C15.9 Oesophagus, unspecified
0.896 0.104 0.000
L50-L54 Urticaria and erythema
0.895 0.105 0.000
E10.2 With renal complications
0.892 0.108 0.000
C18.9 Colon, unspecified
0.891 0.109 0.000
C91.1 Chronic lymphocytic leukaemia
0.889 0.111 0.000
E11.2 With renal complications
0.889 0.111 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.888 0.112 0.000
I74.8 Embolism and thrombosis of other arteries
0.888 0.112 0.000
I08 Multiple valve diseases
0.886 0.114 0.000
E14.8 With unspecified complications
0.881 0.119 0.000
J40-J47 Chronic lower respiratory diseases
0.881 0.119 0.000
K90.9 Intestinal malabsorption, unspecified
0.880 0.120 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.880 0.120 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.877 0.123 0.000
L13 Other bullous disorders
0.877 0.123 0.000
D07.4 Penis
0.877 0.123 0.000
J43 Emphysema
0.873 0.127 0.000
C18.6 Descending colon
0.872 0.128 0.000
C22.0 Liver cell carcinoma
0.870 0.130 0.000
C22.9 Liver, unspecified
0.868 0.132 0.000
E10.8 With unspecified complications
0.867 0.133 0.000
C32 Malignant neoplasm of larynx
0.866 0.134 0.000
I08.0 Disorders of both mitral and aortic valves
0.865 0.135 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.864 0.136 0.000
J43.9 Emphysema, unspecified
0.864 0.136 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.001 0.138 0.862
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.862 0.138 0.000
C95 Leukaemia of unspecified cell type
0.858 0.142 0.000
G50 Disorders of trigeminal nerve
0.855 0.145 0.000
L13.0 Dermatitis herpetiformis
0.854 0.146 0.000
J46 Status asthmaticus
0.854 0.146 0.000
C18.7 Sigmoid colon
0.853 0.147 0.000
Q80-Q89 Other congenital malformations
0.852 0.148 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.848 0.152 0.000
E14.4 With neurological complications
0.848 0.152 0.000
D04.5 Skin of trunk
0.848 0.152 0.000
L44 Other papulosquamous disorders
0.848 0.152 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.848 0.152 0.000
C23 Malignant neoplasm of gallbladder
0.845 0.155 0.000
D53 Other nutritional anaemias
0.845 0.155 0.000
C16 Malignant neoplasm of stomach
0.843 0.157 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.843 0.157 0.000
C60-C63 Malignant neoplasms of male genital organs
0.843 0.157 0.000
L52 Erythema nodosum
0.843 0.157 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.838 0.162 0.000
Chapter VIII Diseases of the ear and mastoid process
0.835 0.165 0.000
C83.3 Large cell (diffuse)
0.834 0.166 0.000
E11.5 With peripheral circulatory complications
0.833 0.167 0.000
L42 Pityriasis rosea
0.832 0.168 0.000
E14.1 With ketoacidosis
0.832 0.168 0.000
D06 Carcinoma in situ of cervix uteri
0.830 0.170 0.000
Q54.1 Hypospadias, penile
0.829 0.171 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.829 0.171 0.000
E10.0 With coma
0.825 0.175 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.823 0.177 0.000
C07 Malignant neoplasm of parotid gland
0.818 0.182 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.815 0.185 0.000
C15.0 Cervical part of oesophagus
0.811 0.189 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.809 0.191 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.808 0.192 0.000
I77 Other disorders of arteries and arterioles
0.808 0.192 0.000
L40.1 Generalised pustular psoriasis
0.807 0.193 0.000
I74.5 Embolism and thrombosis of iliac artery
0.806 0.194 0.000
L40.3 Pustulosis palmaris et plantaris
0.805 0.195 0.000
E03.1 Congenital hypothyroidism without goitre
0.803 0.197 0.000
Q43.0 Meckel's diverticulum
0.799 0.201 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.798 0.202 0.000
C02.9 Tongue, unspecified
0.796 0.204 0.000
E21.0 Primary hyperparathyroidism
0.794 0.206 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.793 0.207 0.000
Q60-Q64 Congenital malformations of the urinary system
0.789 0.211 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.002 0.211 0.787
H90-H95 Other disorders of ear
0.789 0.211 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.788 0.212 0.000
K73.9 Chronic hepatitis, unspecified
0.785 0.215 0.000
C91.0 Acute lymphoblastic leukaemia
0.785 0.215 0.000
K72 Hepatic failure, not elsewhere classified
0.785 0.215 0.000
M45 Ankylosing spondylitis
0.001 0.216 0.783
C34 Malignant neoplasm of bronchus and lung
0.784 0.216 0.000
I73.0 Raynaud's syndrome
0.784 0.216 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.783 0.217 0.000
C32.0 Glottis
0.783 0.217 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.002 0.219 0.780
E27 Other disorders of adrenal gland
0.781 0.219 0.000
E16.1 Other hypoglycaemia
0.776 0.224 0.000
Q00-Q07 Congenital malformations of the nervous system
0.775 0.224 0.000
C15.1 Thoracic part of oesophagus
0.775 0.225 0.000
C21.1 Anal canal
0.775 0.225 0.000
D04.3 Skin of other and unspecified parts of face
0.775 0.225 0.000
I77.1 Stricture of artery
0.775 0.225 0.000
E14.0 With coma
0.774 0.226 0.000
C04 Malignant neoplasm of floor of mouth
0.774 0.226 0.000
Q44.6 Cystic disease of liver
0.773 0.227 0.000
H90 Conductive and sensorineural hearing loss
0.773 0.227 0.000
D80-D89 Certain disorders involving the immune mechanism
0.771 0.229 0.000
C21.0 Anus, unspecified
0.771 0.229 0.000
Q45 Other congenital malformations of digestive system
0.770 0.230 0.000
E14.2 Withrenal complications
0.769 0.231 0.000
E10.4 With neurological complications
0.768 0.232 0.000
C60 Malignant neoplasm of penis
0.766 0.234 0.000
E27.1 Primary adrenocortical insufficiency
0.764 0.236 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.758 0.242 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.757 0.243 0.000
Chapter X Diseases of the respiratory system
0.757 0.243 0.000
C95.9 Leukaemia, unspecified
0.757 0.243 0.000
E07 Other disorders of thyroid
0.756 0.244 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.756 0.244 0.000
D01.3 Anus and anal canal
0.756 0.244 0.000
C22.1 Intrahepatic bile duct carcinoma
0.755 0.245 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.754 0.246 0.000
E34 Other endocrine disorders
0.754 0.246 0.000
E06 Thyroiditis
0.753 0.247 0.000
E10.7 With multiple complications
0.751 0.249 0.000
G00 Bacterial meningitis, not elsewhere classified
0.751 0.249 0.000
D04.9 Skin, unspecified
0.750 0.250 0.000
H90.5 Sensorineural hearing loss, unspecified
0.748 0.252 0.000
Q44.5 Other congenital malformations of bile ducts
0.744 0.256 0.000
D62 Acute posthaemorrhagic anaemia
0.744 0.256 0.000
C62 Malignant neoplasm of testis
0.744 0.256 0.000
Q54.9 Hypospadias, unspecified
0.743 0.257 0.000
I72 Other aneurysm
0.743 0.257 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.742 0.258 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.741 0.259 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.740 0.260 0.000
D53.9 Nutritional anaemia, unspecified
0.740 0.260 0.000
L44.0 Pityriasis rubra pilaris
0.739 0.261 0.000
I06 Rheumatic aortic valve diseases
0.738 0.262 0.000
E10.6 With other specified complications
0.737 0.263 0.000
Q44.7 Other congenital malformations of liver
0.737 0.263 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.736 0.264 0.000
C02.1 Border of tongue
0.736 0.264 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.736 0.264 0.000
C86 Other specified types of T/NK-cell lymphoma
0.735 0.265 0.000
I08.8 Other multiple valve diseases
0.735 0.265 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.734 0.266 0.000
D50.1 Sideropenic dysphagia
0.734 0.266 0.000
Q52 Other congenital malformations of female genitalia
0.734 0.266 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.733 0.267 0.000
D07.2 Vagina
0.733 0.267 0.000
C32.9 Larynx, unspecified
0.731 0.269 0.000
C38.4 Pleura
0.730 0.270 0.000
C84.5 Other and unspecified T-cell lymphomas
0.729 0.271 0.000
K75.9 Inflammatory liver disease, unspecified
0.727 0.272 0.000
Q54.0 Hypospadias, balanic
0.727 0.273 0.000
Q51 Congenital malformations of uterus and cervix
0.726 0.274 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.725 0.275 0.000
C16.6 Greater curvature of stomach, unspecified
0.724 0.276 0.000
E21.2 Other hyperparathyroidism
0.724 0.276 0.000
E21.3 Hyperparathyroidism, unspecified
0.722 0.278 0.000
C13 Malignant neoplasm of hypopharynx
0.721 0.279 0.000
C34.3 Lower lobe, bronchus or lung
0.720 0.280 0.000
I07 Rheumatic tricuspid valve diseases
0.720 0.280 0.000
C84.4 Peripheral T-cell lymphoma
0.720 0.280 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.720 0.280 0.000
C17 Malignant neoplasm of small intestine
0.719 0.280 0.000
D04.2 Skin of ear and external auricular canal
0.719 0.281 0.000
N48.6 Balanitis xerotica obliterans
0.718 0.282 0.000
C82.2 Large cell, follicular
0.718 0.282 0.000
N48 Other disorders of penis
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
C16.8 Overlapping lesion of stomach
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.716 0.284 0.000
D64.3 Other sideroblastic anaemias
0.716 0.284 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.716 0.284 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.716 0.284 0.000
D64.0 Hereditary sideroblastic anaemia
0.716 0.284 0.000
Q89 Other congenital malformations, not elsewhere classified
0.716 0.284 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.715 0.284 0.000
C94 Other leukaemias of specified cell type
0.715 0.284 0.000
Q85 Phakomatoses, not elsewhere classified
0.716 0.284 0.000
E14.5 With peripheral circulatory complications
0.713 0.287 0.000
E15 Nondiabetic hypoglycaemic coma
0.713 0.287 0.000
Q40 Other congenital malformations of upper alimentary tract
0.713 0.287 0.000
E24 Cushing's syndrome
0.712 0.288 0.000
Q43.3 Congenital malformations of intestinal fixation
0.712 0.288 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.710 0.290 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.710 0.290 0.000
E16.4 Abnormal secretion of gastrin
0.710 0.290 0.000
E16.3 Increased secretion of glucagon
0.710 0.290 0.000
G50.1 Atypical facial pain
0.710 0.290 0.000
K71 Toxic liver disease
0.710 0.290 0.000
C60.9 Penis, unspecified
0.710 0.290 0.000
E11.8 With unspecified complications
0.710 0.290 0.000
N00-N08 Glomerular diseases
0.708 0.292 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
D07.6 Other and unspecified male genital organs
0.707 0.293 0.000
D07.3 Other and unspecified female genital organs
0.707 0.293 0.000
D07.0 Endometrium
0.707 0.293 0.000
Chapter XIV Diseases of the genitourinary system
0.706 0.294 0.000
C85.0 Lymphosarcoma
0.706 0.294 0.000
C91.4 Hairy-cell leukaemia
0.706 0.294 0.000
Q43.8 Other specified congenital malformations of intestine
0.706 0.294 0.000
E31 Polyglandular dysfunction
0.705 0.295 0.000
G50.8 Other disorders of trigeminal nerve
0.705 0.295 0.000
D01.0 Colon
0.704 0.296 0.000
K90.3 Pancreatic steatorrhoea
0.703 0.297 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.703 0.297 0.000
K90.1 Tropical sprue
0.703 0.297 0.000
N40-N51 Diseases of male genital organs
0.702 0.298 0.000
Q35-Q37 Cleft lip and cleft palate
0.702 0.298 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.702 0.298 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.702 0.298 0.000
C15.8 Overlapping lesion of oesophagus
0.702 0.298 0.000
C15.2 Abdominal part of oesophagus
0.702 0.298 0.000
D70 Agranulocytosis
0.701 0.299 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.001 0.299 0.701
E03.8 Other specified hypothyroidism
0.701 0.299 0.000
C38.3 Mediastinum, part unspecified
0.701 0.299 0.000
H80-H83 Diseases of inner ear
0.699 0.301 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.698 0.301 0.000
C84.0 Mycosis fungoides
0.698 0.302 0.000
C12 Malignant neoplasm of pyriform sinus
0.698 0.302 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.698 0.302 0.000
C91.5 Adult T-cell leukaemia
0.698 0.302 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.697 0.303 0.000
I72.4 Aneurysm of artery of lower extremity
0.695 0.305 0.000
H90.0 Conductive hearing loss, bilateral
0.694 0.306 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.694 0.306 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.694 0.306 0.000
G51.4 Facial myokymia
0.693 0.307 0.000
G51.2 Melkersson's syndrome
0.693 0.307 0.000
G51.1 Geniculate ganglionitis
0.693 0.307 0.000
C16.9 Stomach, unspecified
0.692 0.308 0.000
Q39 Congenital malformations of oesophagus
0.691 0.309 0.000
Q54.8 Other hypospadias
0.691 0.309 0.000
C22.7 Other specified carcinomas of liver
0.691 0.309 0.000
C22.4 Other sarcomas of liver
0.691 0.309 0.000
C22.3 Angiosarcoma of liver
0.691 0.309 0.000
C22.2 Hepatoblastoma
0.691 0.309 0.000
J43.2 Centrilobular emphysema
0.689 0.311 0.000
Q43.1 Hirschsprung's disease
0.688 0.312 0.000
D51.2 Transcobalamin II deficiency
0.688 0.312 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.688 0.312 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.687 0.313 0.000
K72.9 Hepatic failure, unspecified
0.687 0.313 0.000
E23 Hypofunction and other disorders of pituitary gland
0.686 0.314 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.685 0.315 0.000
N04 Nephrotic syndrome
0.685 0.315 0.000
C91.9 Lymphoid leukaemia, unspecified
0.684 0.316 0.000
D80 Immunodeficiency with predominantly antibody defects
0.684 0.316 0.000
N05 Unspecified nephritic syndrome
0.684 0.316 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.683 0.317 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.683 0.317 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.682 0.318 0.000
C91.7 Other lymphoid leukaemia
0.682 0.318 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.682 0.318 0.000
C91.3 Prolymphocytic leukaemia
0.682 0.318 0.000
C91.2 Subacute lymphocytic leukaemia
0.682 0.318 0.000
G36 Other acute disseminated demyelination
0.018 0.318 0.664
M45.X2 Ankylosing spondylitis (Cervical region)
0.001 0.318 0.681
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.681 0.319 0.000
C31 Malignant neoplasm of accessory sinuses
0.681 0.319 0.000
C33 Malignant neoplasm of trachea
0.681 0.319 0.000
I09 Other rheumatic heart diseases
0.681 0.319 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.679 0.321 0.000
G00.1 Pneumococcal meningitis
0.679 0.321 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.679 0.321 0.000
C16.2 Body of stomach
0.678 0.322 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.677 0.322 0.000
D09 Carcinoma in situ of other and unspecified sites
0.677 0.323 0.000
E11.6 With other specified complications
0.676 0.323 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.676 0.323 0.000
G70-G73 Diseases of myoneural junction and muscle
0.675 0.325 0.000
Q53 Undescended testicle
0.675 0.325 0.000
D06.9 Cervix, unspecified
0.675 0.325 0.000
D04.4 Skin of scalp and neck
0.673 0.327 0.000
N48.0 Leukoplakia of penis
0.672 0.328 0.000
K75.2 Nonspecific reactive hepatitis
0.671 0.328 0.000
K75.1 Phlebitis of portal vein
0.671 0.328 0.000
I00-I02 Acute rheumatic fever
0.670 0.330 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.670 0.330 0.000
C00 Malignant neoplasm of lip
0.670 0.330 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.669 0.331 0.000
C15.3 Upper third of oesophagus
0.669 0.331 0.000
K77 Liver disorders in diseases classified elsewhere
0.668 0.332 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.668 0.332 0.000
E32 Diseases of thymus
0.668 0.332 0.000
E30 Disorders of puberty, not elsewhere classified
0.668 0.332 0.000
E25 Adrenogenital disorders
0.668 0.332 0.000
D04.8 Skin of other sites
0.667 0.333 0.000
D04.0 Skin of lip
0.667 0.333 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.667 0.333 0.000
J45.8 Mixed asthma
0.666 0.334 0.000
J43.8 Other emphysema
0.665 0.334 0.000
G50.0 Trigeminal neuralgia
0.665 0.335 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.665 0.335 0.000
C05 Malignant neoplasm of palate
0.664 0.336 0.000
C88 Malignant immunoproliferative diseases
0.663 0.337 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.662 0.338 0.000
Q43.7 Persistent cloaca
0.662 0.338 0.000
Q43.6 Congenital fistula of rectum and anus
0.662 0.338 0.000
Q43.5 Ectopic anus
0.662 0.338 0.000
Q43.4 Duplication of intestine
0.662 0.338 0.000
Q43.2 Other congenital functional disorders of colon
0.662 0.338 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.661 0.339 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.661 0.339 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.661 0.339 0.000
C84.3 Lymphoepithelioid lymphoma
0.661 0.339 0.000
C84.2 T-zone lymphoma
0.661 0.339 0.000
C84.1 Sezary's diease
0.661 0.339 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.659 0.340 0.000
L43 Lichen planus
0.659 0.341 0.000
C21.2 Cloacogenic zone
0.659 0.341 0.000
C62.9 Testis, unspecified
0.659 0.341 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.657 0.343 0.000
N04.9 Unspecified
0.657 0.343 0.000
G37.5 Concentric sclerosis [Balo]
0.003 0.344 0.652
G37.4 Subacute necrotising myelitis
0.003 0.344 0.652
G37.2 Central pontine myelinolysis
0.003 0.344 0.652
G37.1 Central demyelination of corpus callosum
0.003 0.344 0.652
G37.0 Diffuse sclerosis
0.003 0.344 0.652
J45.1 Nonallergic asthma
0.655 0.345 0.000
Q54.4 Congenital chordee
0.652 0.348 0.000
Q54.3 Hypospadias, perineal
0.652 0.348 0.000
Q54.2 Hypospadias, penoscrotal
0.652 0.348 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.651 0.348 0.000
L14 Bullous disorders in diseases classified elsewhere
0.651 0.349 0.000
Q44.4 Choledochal cyst
0.648 0.351 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.648 0.351 0.000
Q44.2 Atresia of bile ducts
0.648 0.351 0.000
Q44.1 Other congenital malformations of gallbladder
0.648 0.351 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.648 0.351 0.000
Q83 Congenital malformations of breast
0.648 0.352 0.000
E28 Ovarian dysfunction
0.647 0.353 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.647 0.353 0.000
D06.0 Endocervix
0.647 0.353 0.000
C04.9 Floor of mouth, unspecified
0.646 0.353 0.000
Q55 Other congenital malformations of male genital organs
0.646 0.354 0.000
L53 Other erythematous conditions
0.646 0.354 0.000
I08.9 Multiple valve disease, unspecified
0.645 0.355 0.000
G52 Disorders of other cranial nerves
0.644 0.356 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.644 0.356 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.644 0.356 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.644 0.356 0.000
C34.2 Middle lobe, bronchus or lung
0.644 0.356 0.000
C03 Malignant neoplasm of gum
0.643 0.357 0.000
D55-D59 Haemolytic anaemias
0.642 0.358 0.000
Q64 Other congenital malformations of urinary system
0.642 0.358 0.000
L54 Erythema in diseases classified elsewhere
0.641 0.358 0.000
E07.8 Other specified disorders of thyroid
0.639 0.361 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.639 0.361 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.638 0.362 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.637 0.363 0.000
Q03 Congenital hydrocephalus
0.637 0.363 0.000
E21.4 Other specified disorders of parathyroid gland
0.637 0.363 0.000
Q85.9 Phakomatosis, unspecified
0.636 0.364 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.636 0.364 0.000
C37 Malignant neoplasm of thymus
0.636 0.364 0.000
L50 Urticaria
0.635 0.365 0.000
H93 Other disorders of ear, not elsewhere classified
0.634 0.366 0.000
D04.1 Skin of eyelid, including canthus
0.633 0.367 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.633 0.367 0.000
E06.3 Autoimmune thyroiditis
0.630 0.370 0.000
L40.8 Other psoriasis
0.630 0.370 0.000
D01.9 Digestive organ, unspecified
0.629 0.371 0.000
D01.7 Other specified digestive organs
0.629 0.371 0.000
D01.5 Liver, gallbladder and bile ducts
0.629 0.371 0.000
D01.4 Other and unspecified parts of intestine
0.629 0.371 0.000
D01.2 Rectum
0.629 0.371 0.000
D01.1 Rectosigmoid junction
0.629 0.371 0.000
L13.9 Bullous disorder, unspecified
0.629 0.371 0.000
L13.8 Other specified bullous disorders
0.629 0.371 0.000
L13.1 Subcorneal pustular dermatitis
0.629 0.371 0.000
N05.2 Diffuse membranous glomerulonephritis
0.627 0.373 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.627 0.373 0.000
L10 Pemphigus
0.626 0.373 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.626 0.374 0.000
J43.1 Panlobular emphysema
0.626 0.374 0.000
J43.0 MacLeod's syndrome
0.626 0.374 0.000
N48.8 Other specified disorders of penis
0.626 0.374 0.000
E10.5 With peripheral circulatory complications
0.625 0.375 0.000
I65.2 Occlusion and stenosis of carotid artery
0.625 0.375 0.000
I60-I69 Cerebrovascular diseases
0.625 0.375 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.624 0.376 0.000
Chapter I Certain infectious and parasitic diseases
0.624 0.376 0.000
Q04 Other congenital malformations of brain
0.623 0.376 0.000
C34.8 Overlapping lesion of bronchus and lung
0.622 0.378 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.622 0.378 0.000
E50-E64 Other nutritional deficiencies
0.622 0.378 0.000
C32.8 Overlapping lesion of larynx
0.621 0.379 0.000
C32.3 Laryngeal cartilage
0.621 0.379 0.000
C32.2 Subglottis
0.621 0.379 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.620 0.380 0.000
H80 Otosclerosis
0.620 0.380 0.000
Q45.8 Other specified congenital malformations of digestive system
0.620 0.380 0.000
E34.9 Endocrine disorder, unspecified
0.620 0.380 0.000
C02.8 Overlapping lesion of tongue
0.620 0.380 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.620 0.380 0.000
C02.0 Dorsal surface of tongue
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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