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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2272592
log Bayes Factor = 130.912
Chromosome 6   position 31,698,352  (GRCh37) Explore rs2272592 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
# Top node
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
I20-I25 Ischaemic heart diseases
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
J45 Asthma
0.000 0.001 0.999
H36.0 Diabetic retinopathy
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
G20 Parkinson's disease
0.998 0.002 0.000
G20-G26 Extrapyramidal and movement disorders
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.002 0.998
J33.9 Nasal polyp, unspecified
0.000 0.003 0.997
J33 Nasal polyp
0.000 0.003 0.997
E14 Unspecified diabetes mellitus
0.000 0.004 0.996
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
E83.1 Disorders of iron metabolism
0.996 0.004 0.000
I22 Subsequent myocardial infarction
0.000 0.005 0.995
M45 Ankylosing spondylitis
0.000 0.006 0.994
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.006 0.994
M45-M49 Spondylopathies
0.000 0.007 0.993
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.008 0.992
J30-J39 Other diseases of upper respiratory tract
0.000 0.009 0.991
H43-H45 Disorders of vitreous body and globe
0.000 0.011 0.989
E07 Other disorders of thyroid
0.000 0.011 0.989
G37 Other demyelinating diseases of central nervous system
0.988 0.012 0.000
E14.3 With ophthalmic complications
0.000 0.013 0.987
H43 Disorders of vitreous body
0.000 0.013 0.987
E16 Other disorders of pancreatic internal secretion
0.000 0.013 0.987
E05.9 Thyrotoxicosis, unspecified
0.000 0.015 0.985
M05 Seropositive rheumatoid arthritis
0.000 0.015 0.985
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.018 0.982
E07.9 Disorder of thyroid, unspecified
0.000 0.018 0.982
E78.0 Pure hypercholesterolaemia
0.000 0.018 0.982
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.020 0.980
E70-E90 Metabolic disorders
0.001 0.022 0.978
E16.2 Hypoglycaemia, unspecified
0.000 0.023 0.977
H43.8 Other disorders of vitreous body
0.000 0.024 0.976
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.026 0.974
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.026 0.974
G37.9 Demyelinating disease of central nervous system, unspecified
0.974 0.026 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.034 0.966
I12 Hypertensive renal disease
0.000 0.035 0.965
L40 Psoriasis
0.962 0.037 0.001
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.040 0.960
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.050 0.950
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.054 0.946
J33.0 Polyp of nasal cavity
0.000 0.054 0.946
H35 Other retinal disorders
0.000 0.056 0.944
I12.9 Hypertensive renal disease without renal failure
0.000 0.060 0.940
I20 Angina pectoris
0.000 0.061 0.939
I15 Secondary hypertension
0.000 0.061 0.939
I25 Chronic ischaemic heart disease
0.000 0.063 0.937
E10.5 With peripheral circulatory complications
0.000 0.071 0.929
H35.8 Other specified retinal disorders
0.000 0.073 0.927
J86 Pyothorax
0.000 0.079 0.921
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.083 0.917
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.083 0.917
E10.2 With renal complications
0.000 0.088 0.912
E14.9 Without complications
0.000 0.089 0.911
J33.8 Other polyp of sinus
0.000 0.089 0.911
L40.5 Arthropathic psoriasis
0.908 0.092 0.000
E83 Disorders of mineral metabolism
0.883 0.096 0.021
L40.0 Psoriasis vulgaris
0.903 0.096 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.101 0.899
I20.9 Angina pectoris, unspecified
0.000 0.105 0.895
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.108 0.892
I20.1 Angina pectoris with documented spasm
0.000 0.111 0.889
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.111 0.889
H34 Retinal vascular occlusions
0.000 0.111 0.889
J44 Other chronic obstructive pulmonary disease
0.000 0.112 0.888
G30-G32 Other degenerative diseases of the nervous system
0.884 0.116 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.123 0.877
I25.5 Ischaemic cardiomyopathy
0.000 0.124 0.876
G40-G47 Episodic and paroxysmal disorders
0.874 0.126 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.128 0.872
E10.8 With unspecified complications
0.000 0.130 0.870
E78.2 Mixed hyperlipidaemia
0.000 0.132 0.868
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.132 0.868
G40 Epilepsy
0.863 0.137 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.139 0.861
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.140 0.860
M06.0 Seronegative rheumatoid arthritis
0.000 0.143 0.857
G37.8 Other specified demyelinating diseases of central nervous system
0.857 0.143 0.000
J86.9 Pyothorax without fistula
0.000 0.149 0.851
E06 Thyroiditis
0.000 0.149 0.851
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.153 0.847
J37 Chronic laryngitis and laryngotracheitis
0.000 0.157 0.843
E83.3 Disorders of phosphorus metabolism
0.837 0.159 0.004
J46 Status asthmaticus
0.000 0.162 0.838
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.168 0.832
E13 Other specified diabetes mellitus
0.000 0.169 0.831
M65-M68 Disorders of synovium and tendon
0.000 0.171 0.829
H43.3 Other vitreous opacities
0.000 0.174 0.826
G24 Dystonia
0.826 0.174 0.000
M06.3 Rheumatoid nodule
0.000 0.175 0.825
J85 Abscess of lung and mediastinum
0.000 0.176 0.824
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.178 0.822
E10.6 With other specified complications
0.000 0.178 0.822
H43.9 Disorder of vitreous body, unspecified
0.000 0.178 0.822
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.816 0.184 0.000
E11.9 Without complications
0.000 0.184 0.816
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.187 0.813
K90 Intestinal malabsorption
0.000 0.192 0.808
J42 Unspecified chronic bronchitis
0.000 0.200 0.800
J86.0 Pyothorax with fistula
0.000 0.200 0.800
H35.4 Peripheral retinal degeneration
0.000 0.200 0.800
H43.2 Crystalline deposits in vitreous body
0.000 0.202 0.798
E03.8 Other specified hypothyroidism
0.000 0.206 0.794
I15.9 Seconday hypertension, unspecified
0.000 0.207 0.793
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.208 0.792
E16.1 Other hypoglycaemia
0.000 0.211 0.789
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.788 0.212 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.212 0.788
H31 Other disorders of choroid
0.000 0.224 0.776
M65 Synovitis and tenosynovitis
0.000 0.227 0.773
M06.4 Inflammatory polyarthropathy
0.000 0.229 0.771
E11.0 With coma
0.000 0.231 0.769
H43.1 Vitreous haemorrhage
0.000 0.231 0.769
E78.1 Pure hyperglyceridaemia
0.000 0.232 0.768
I25.1 Atherosclerotic heart disease
0.000 0.233 0.767
E89.0 Postprocedural hypothyroidism
0.000 0.236 0.763
I23 Certain current complications following acute myocardial infarction
0.000 0.238 0.762
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.760 0.240 0.000
H30 Chorioretinal inflammation
0.000 0.240 0.760
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.244 0.756
H34.2 Other retinal artery occlusions
0.000 0.246 0.754
H35.5 Hereditary retinal dystrophy
0.000 0.250 0.750
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.250 0.750
H35.2 Other proliferative retinopathy
0.000 0.251 0.749
I25.2 Old myocardial infarction
0.000 0.255 0.745
G46 Vascular syndromes of brain in cerebrovascular diseases
0.745 0.255 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.255 0.745
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.257 0.743
G24.9 Dystonia, unspecified
0.741 0.259 0.000
E14.6 With other specified complications
0.000 0.260 0.740
J37.0 Chronic laryngitis
0.000 0.262 0.738
E14.1 With ketoacidosis
0.000 0.270 0.730
H25-H28 Disorders of lens
0.000 0.271 0.729
G41 Status epilepticus
0.727 0.273 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.274 0.726
L40.3 Pustulosis palmaris et plantaris
0.725 0.274 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.276 0.724
E83.9 Disorder of mineral metabolism, unspecified
0.711 0.277 0.013
E06.3 Autoimmune thyroiditis
0.000 0.280 0.720
G40.9 Epilepsy, unspecified
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E79 Disorders of purine and pyrimidine metabolism
0.001 0.283 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
J45.8 Mixed asthma
0.000 0.284 0.716
J45.1 Nonallergic asthma
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
J41 Simple and mucopurulent chronic bronchitis
0.000 0.284 0.716
G23 Other degenerative diseases of basal ganglia
0.716 0.284 0.000
G21 Secondary Parkinsonism
0.716 0.284 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.716 0.284 0.000
G22 Parkinsonism in diseases classified elsewhere
0.716 0.284 0.000
J33.1 Polypoid sinus degeneration
0.000 0.285 0.715
E14.8 With unspecified complications
0.000 0.285 0.714
E14.7 With multiple complications
0.000 0.285 0.714
E14.5 With peripheral circulatory complications
0.000 0.285 0.714
E14.2 Withrenal complications
0.000 0.285 0.714
E14.0 With coma
0.000 0.285 0.714
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.286 0.714
E89.3 Postprocedural hypopituitarism
0.000 0.286 0.713
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.287 0.713
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.287 0.713
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.287 0.713
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.287 0.713
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.287 0.713
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.287 0.713
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.287 0.713
E15 Nondiabetic hypoglycaemic coma
0.000 0.289 0.711
E13.9 Without complications
0.000 0.289 0.711
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.291 0.709
E07.1 Dyshormogenetic goitre
0.000 0.291 0.709
E07.0 Hypersecretion of calcitonin
0.000 0.291 0.709
G37.5 Concentric sclerosis [Balo]
0.708 0.292 0.000
G37.4 Subacute necrotising myelitis
0.708 0.292 0.000
G37.2 Central pontine myelinolysis
0.708 0.292 0.000
G37.1 Central demyelination of corpus callosum
0.708 0.292 0.000
G37.0 Diffuse sclerosis
0.708 0.292 0.000
E14.4 With neurological complications
0.000 0.292 0.708
I24 Other acute ischaemic heart diseases
0.000 0.292 0.708
H43.0 Vitreous prolapse
0.000 0.292 0.707
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.293 0.707
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.293 0.707
E16.4 Abnormal secretion of gastrin
0.000 0.293 0.707
E16.3 Increased secretion of glucagon
0.000 0.293 0.707
M49 Spondylopathies in diseases classified elsewhere
0.000 0.294 0.706
M05.8 Other seropositive rheumatoid arthritis
0.000 0.294 0.706
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.294 0.706
M05.2 Rheumatoid vasculitis
0.000 0.294 0.706
M05.1 Rheumatoid lung disease
0.000 0.294 0.706
M05.0 Felty's syndrome
0.000 0.294 0.706
K90.9 Intestinal malabsorption, unspecified
0.000 0.295 0.705
L40.1 Generalised pustular psoriasis
0.705 0.295 0.000
G40.5 Special epileptic syndromes
0.704 0.296 0.000
H35.6 Retinal haemorrhage
0.000 0.297 0.703
E78.3 Hyperchylomicronaemia
0.000 0.298 0.702
M70-M79 Other soft tissue disorders
0.000 0.298 0.702
E89.2 Postprocedural hypoparathyroidism
0.000 0.298 0.702
G31.9 Degenerative disease of nervous system, unspecified
0.702 0.298 0.000
E77 Disorders of glycoprotein metabolism
0.001 0.298 0.701
E76 Disorders of glycosaminoglycan metabolism
0.001 0.298 0.701
E72 Other disorders of amino-acid metabolism
0.001 0.298 0.701
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.298 0.701
E70 Disorders of aromatic amino-acid metabolism
0.001 0.298 0.701
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.298 0.701
H34.8 Other retinal vascular occlusions
0.000 0.299 0.701
G30 Alzheimer's disease
0.699 0.301 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.302 0.698
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.302 0.698
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.302 0.698
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.302 0.698
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.302 0.698
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.302 0.698
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.302 0.698
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.302 0.698
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.302 0.698
E83.5 Disorders of calcium metabolism
0.696 0.303 0.001
I12.0 Hypertensive renal disease with renal failure
0.000 0.303 0.697
M14 Arthropathies in other diseases classified elsewhere
0.000 0.303 0.697
H34.1 Central retinal artery occlusion
0.000 0.305 0.695
M11 Other crystal arthropathies
0.000 0.308 0.692
E74 Other disorders of carbohydrate metabolism
0.001 0.309 0.691
J31.0 Chronic rhinitis
0.000 0.309 0.691
L40.4 Guttate psoriasis
0.690 0.310 0.001
L40.2 Acrodermatitis continua
0.690 0.310 0.001
J31.2 Chronic pharyngitis
0.000 0.311 0.689
J85.2 Abscess of lung without pneumonia
0.000 0.312 0.688
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.686 0.314 0.000
I00-I02 Acute rheumatic fever
0.000 0.316 0.684
E05.8 Other thyrotoxicosis
0.000 0.316 0.684
E11.5 With peripheral circulatory complications
0.000 0.318 0.682
H27 Other disorders of lens
0.000 0.319 0.681
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.680 0.320 0.000
I22.8 Subsequent myocardial infarction of other sites
0.000 0.320 0.680
E78.6 Lipoprotein deficiency
0.000 0.321 0.678
E40-E46 Malnutrition
0.000 0.322 0.678
J95-J99 Other diseases of the respiratory system
0.000 0.322 0.678
H35.1 Retinopathy of prematurity
0.000 0.323 0.677
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.324 0.675
M75 Shoulder lesions
0.000 0.325 0.675
I15.8 Other secondary hypertension
0.000 0.326 0.673
I15.2 Hypertension secondary to endocrine disorders
0.000 0.326 0.673
I15.0 Renovascular hypertension
0.000 0.326 0.673
G25 Other extrapyramidal and movement disorders
0.672 0.328 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.672 0.328 0.000
I25.6 Silent myocardial ischaemia
0.000 0.328 0.672
I11 Hypertensive heart disease
0.000 0.330 0.670
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.330 0.670
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.331 0.669
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.332 0.667
M75.0 Adhesive capsulitis of shoulder
0.000 0.333 0.667
H35.7 Separation of retinal layers
0.000 0.333 0.667
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.333 0.666
K90-K93 Other diseases of the digestive system
0.000 0.338 0.662
I25.4 Coronary artery aneurysm
0.000 0.338 0.662
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.660 0.340 0.000
E84 Cystic fibrosis
0.001 0.342 0.657
E78.5 Hyperlipidaemia, unspecified
0.000 0.343 0.657
E07.8 Other specified disorders of thyroid
0.000 0.345 0.655
E11.1 With ketoacidosis
0.000 0.345 0.655
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.345 0.655
M12 Other specific arthropathies
0.000 0.346 0.654
E06.9 Thyroiditis, unspecified
0.000 0.346 0.654
Chapter XI Diseases of the digestive system
0.000 0.348 0.652
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.349 0.651
K70-K77 Diseases of liver
0.000 0.350 0.650
K74 Fibrosis and cirrhosis of liver
0.000 0.350 0.650
J85.1 Abscess of lung with pneumonia
0.000 0.350 0.650
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.351 0.649
E78.4 Other hyperlipidaemia
0.000 0.351 0.649
E83.8 Other disorders of mineral metabolism
0.633 0.352 0.015
E83.2 Disorders of zinc metabolism
0.633 0.352 0.015
E83.0 Disorders of copper metabolism
0.633 0.352 0.015
K74.3 Primary biliary cirrhosis
0.000 0.352 0.648
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.360 0.639
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.360 0.639
E89.5 Postprocedural testicular hypofunction
0.000 0.360 0.639
E89.1 Postprocedural hypoinsulinaemia
0.000 0.360 0.639
H34.0 Transient retinal artery occlusion
0.000 0.363 0.637
G24.8 Other dystonia
0.635 0.365 0.000
H34.9 Retinal vascular occlusion, unspecified
0.000 0.368 0.632
H31.0 Chorioretinal scars
0.000 0.369 0.631
G00-G09 Inflammatory diseases of the central nervous system
0.629 0.371 0.000
J60-J70 Lung diseases due to external agents
0.000 0.372 0.628
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.626 0.374 0.000
E11.7 With multiple complications
0.000 0.375 0.625
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.625 0.375 0.000
I25.3 Aneurysm of heart
0.000 0.378 0.622
L40.8 Other psoriasis
0.621 0.378 0.001
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.380 0.620
G40.4 Other generalised epilepsy and epileptic syndromes
0.618 0.381 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.385 0.614
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.385 0.614
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.385 0.614
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.385 0.614
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.385 0.614
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.385 0.614
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.386 0.614
E11.6 With other specified complications
0.000 0.387 0.613
G41.0 Grand mal status epilepticus
0.611 0.389 0.000
E06.5 Other chronic thyroiditis
0.000 0.390 0.610
E06.4 Drug-induced thyroiditis
0.000 0.390 0.610
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.390 0.610
E06.1 Subacute thyroiditis
0.000 0.390 0.610
E06.0 Acute thyroiditis
0.000 0.390 0.610
G46.4 Cerebellar stroke syndrome
0.608 0.392 0.000
J31.1 Chronic nasopharyngitis
0.000 0.392 0.607
M65.8 Other synovitis and tenosynovitis
0.000 0.393 0.607
K74.5 Biliary cirrhosis, unspecified
0.000 0.394 0.606
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.395 0.605
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.395 0.605
J37.1 Chronic laryngotracheitis
0.000 0.395 0.605
M00-M03 Infectious arthropathies
0.000 0.396 0.603
G80-G83 Cerebral palsy and other paralytic syndromes
0.602 0.398 0.000
G46.7 Other lacunar syndromes
0.602 0.398 0.000
M80-M85 Disorders of bone density and structure
0.000 0.399 0.601
K75 Other inflammatory liver diseases
0.000 0.402 0.598
H35.9 Retinal disorder, unspecified
0.000 0.402 0.598
G40.8 Other epilepsy
0.597 0.403 0.000
E13.8 With unspecified complications
0.000 0.404 0.596
E13.7 With multiple complications
0.000 0.404 0.596
E13.6 With other specified complications
0.000 0.404 0.596
E13.5 With peripheral circulatory complications
0.000 0.404 0.596
E13.4 With neurological complications
0.000 0.404 0.596
E13.3 With ophthalmic complications
0.000 0.404 0.596
E13.2 With renal complications
0.000 0.404 0.596
E13.1 With ketoacidosis
0.000 0.404 0.596
E13.0 With coma
0.000 0.404 0.596
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.405 0.595
E89.4 Postprocedural ovarian failure
0.000 0.406 0.594
H27.0 Aphakia
0.000 0.406 0.594
K90.8 Other intestinal malabsorption
0.000 0.407 0.593
M75.2 Bicipital tendinitis
0.000 0.407 0.593
G24.4 Idiopathic orofacial dystonia
0.592 0.408 0.000
G24.2 Idiopathic nonfamilial dystonia
0.592 0.408 0.000
G24.1 Idiopathic familial dystonia
0.592 0.408 0.000
G24.0 Drug-induced dystonia
0.592 0.408 0.000
I23.8 Other current complications following acute myocardial infarction
0.000 0.409 0.591
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.409 0.591
M06.38 Rheumatoid nodule (Other)
0.000 0.409 0.591
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.409 0.591
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.409 0.591
M06.33 Rheumatoid nodule (Forearm)
0.000 0.409 0.591
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.409 0.591
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.409 0.591
J85.3 Abscess of mediastinum
0.000 0.409 0.591
J85.0 Gangrene and necrosis of lung
0.000 0.409 0.591
H40-H42 Glaucoma
0.000 0.409 0.591
H31.1 Choroidal degeneration
0.000 0.411 0.589
H30.9 Chorioretinal inflammation, unspecified
0.000 0.412 0.588
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.413 0.587
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.413 0.587
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.414 0.586
M65.1 Other infective (teno)synovitis
0.000 0.415 0.585
G30.9 Alzheimer's disease, unspecified
0.582 0.418 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.420 0.579
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.420 0.579
K90.1 Tropical sprue
0.000 0.420 0.579
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.422 0.578
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.423 0.577
G70-G73 Diseases of myoneural junction and muscle
0.575 0.425 0.000
E11.8 With unspecified complications
0.000 0.428 0.572
G24.3 Spasmodic torticollis
0.570 0.430 0.000
K75.4 Autoimmune hepatitis
0.000 0.432 0.568
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.433 0.567
H27.8 Other specified disorders of lens
0.000 0.434 0.566
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.438 0.562
I05-I09 Chronic rheumatic heart diseases
0.000 0.439 0.561
H27.1 Dislocation of lens
0.000 0.442 0.558
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.443 0.557
H31.9 Disorder of choroid, unspecified
0.000 0.443 0.556
H31.4 Choroidal detachment
0.000 0.443 0.556
H31.3 Choroidal haemorrhage and rupture
0.000 0.443 0.556
H31.2 Hereditary choroidal dystrophy
0.000 0.443 0.556
K72 Hepatic failure, not elsewhere classified
0.000 0.445 0.555
G30.8 Other Alzheimer's disease
0.555 0.445 0.000
M65.2 Calcific tendinitis
0.000 0.446 0.554
M65.0 Abscess of tendon sheath
0.000 0.446 0.554
M60-M63 Disorders of muscles
0.000 0.446 0.554
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.447 0.553
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.447 0.553
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.447 0.553
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.447 0.553
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.447 0.553
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.447 0.553
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.447 0.553
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.447 0.553
E11.2 With renal complications
0.000 0.448 0.552
K73 Chronic hepatitis, not elsewhere classified
0.000 0.451 0.549
M82 Osteoporosis in diseases classified elsewhere
0.000 0.452 0.548
G31.2 Degeneration of nervous system due to alcohol
0.546 0.453 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.454 0.546
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.454 0.546
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.454 0.546
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.454 0.546
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.454 0.546
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.454 0.546
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.454 0.546
G31.1 Senile degeneration of brain, not elsewhere classified
0.545 0.455 0.000
H30.8 Other chorioretinal inflammations
0.000 0.455 0.545
H30.2 Posterior cyclitis
0.000 0.455 0.545
H30.1 Disseminated chorioretinal inflammation
0.000 0.455 0.545
H30.0 Focal chorioretinal inflammation
0.000 0.455 0.545
G11 Hereditary ataxia
0.544 0.456 0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.458 0.542
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.458 0.542
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.458 0.542
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.458 0.542
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.458 0.542
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.458 0.542
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.458 0.542
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.458 0.542
G41.9 Status epilepticus, unspecified
0.541 0.458 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.534 0.466 0.000
G46.6 Pure sensory lacunar syndrome
0.534 0.466 0.000
G46.5 Pure motor lacunar syndrome
0.534 0.466 0.000
G46.3 Brain stem stroke syndrome
0.534 0.466 0.000
G46.2 Posterior cerebral artery syndrome
0.534 0.466 0.000
G46.1 Anterior cerebral artery syndrome
0.534 0.466 0.000
G46.0 Middle cerebral artery syndrome
0.534 0.466 0.000
M75.5 Bursitis of shoulder
0.000 0.467 0.533
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.468 0.532
M65.84 Other synovitis and tenosynovitis (Hand)
0.000 0.468 0.532
J32 Chronic sinusitis
0.000 0.468 0.532
G90-G99 Other disorders of the nervous system
0.532 0.468 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.469 0.531
M86-M90 Other osteopathies
0.000 0.469 0.531
E73 Lactose intolerance
0.001 0.470 0.529
G25.1 Drug-induced tremor
0.530 0.470 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.471 0.528
M70.4 Prepatellar bursitis
0.000 0.474 0.526
E88 Other metabolic disorders
0.001 0.474 0.525
E85 Amyloidosis
0.001 0.475 0.524
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.477 0.522
G41.8 Other status epilepticus
0.521 0.479 0.000
G41.2 Complex partial status epilepticus
0.521 0.479 0.000
G41.1 Petit mal status epilepticus
0.521 0.479 0.000
J69 Pneumonitis due to solids and liquids
0.000 0.480 0.520
K75.0 Abscess of liver
0.000 0.481 0.519
M91-M94 Chondropathies
0.000 0.484 0.515
G31.0 Circumscribed brain atrophy
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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