TreeWAS – Variant ID: rs2281388

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J45.9 Asthma, unspecified	0.000	0.007	0.993
E03.9 Hypothyroidism, unspecified	0.000	0.020	0.980
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.840	0.160	0.000
M50-M54 Other dorsopathies	0.825	0.175	0.000
M15-M19 Arthrosis	0.820	0.180	0.000
M20-M25 Other joint disorders	0.820	0.180	0.000
M20 Acquired deformities of fingers and toes	0.816	0.184	0.000
M50 Cervical disk disorders	0.795	0.205	0.000
M16 Coxarthrosis [arthrosis of hip]	0.793	0.207	0.000
M20.5 Other deformities of toe(s) (acquired)	0.786	0.214	0.000
M16.0 Primary coxarthrosis, bilateral	0.768	0.232	0.000
E03 Other hypothyroidism	0.002	0.233	0.764
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.766	0.234	0.000
M20.1 Hallux valgus (acquired)	0.763	0.237	0.000
# Top node	0.757	0.243	0.000
S60-S69 Injuries to the wrist and hand	0.757	0.243	0.000
M19 Other arthrosis	0.755	0.245	0.000
M51 Other intervertebral disk disorders	0.745	0.255	0.000
M86-M90 Other osteopathies	0.739	0.261	0.000
Chapter VIII Diseases of the ear and mastoid process	0.739	0.261	0.000
M50.1 Cervical disk disorder with radiculopathy	0.732	0.268	0.000
Chapter VI Diseases of the nervous system	0.726	0.274	0.000
M16.1 Other primary coxarthrosis	0.719	0.281	0.000
M19.9 Arthrosis, unspecified	0.713	0.287	0.000
S68 Traumatic amputation of wrist and hand	0.708	0.292	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.708	0.292	0.000
H65-H75 Diseases of middle ear and mastoid	0.707	0.293	0.000
M20.4 Other hammer toe(s) (acquired)	0.699	0.301	0.000
M21 Other acquired deformities of limbs	0.688	0.312	0.000
Chapter XX External causes of morbidity and mortality	0.686	0.314	0.000
G90-G99 Other disorders of the nervous system	0.681	0.319	0.000
M24 Other specific joint derangements	0.681	0.319	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.674	0.326	0.000
Chapter I Certain infectious and parasitic diseases	0.672	0.328	0.000
M50.3 Other cervical disk degeneration	0.670	0.330	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.669	0.331	0.000
S40-S49 Injuries to the shoulder and upper arm	0.665	0.335	0.000
M51.2 Other specified intervertebral disk displacement	0.664	0.336	0.000
M20.2 Hallux rigidus	0.662	0.338	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.659	0.341	0.000
S64 Injury of nerves at wrist and hand level	0.659	0.341	0.000
M50.2 Other cervical disk displacement	0.659	0.341	0.000
S67 Crushing injury of wrist and hand	0.655	0.344	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.654	0.346	0.000
M65-M68 Disorders of synovium and tendon	0.648	0.352	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.647	0.353	0.000
M89 Other disorders of bone	0.643	0.357	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.642	0.358	0.000
M60-M63 Disorders of muscles	0.637	0.363	0.000
H66 Suppurative and unspecified otitis media	0.635	0.365	0.000
H72 Perforation of tympanic membrane	0.631	0.369	0.000
H90-H95 Other disorders of ear	0.631	0.369	0.000
M91-M94 Chondropathies	0.626	0.374	0.000
S70-S79 Injuries to the hip and thigh	0.625	0.375	0.000
G95 Other diseases of spinal cord	0.623	0.377	0.000
Chapter XXII Codes for special purposes	0.621	0.379	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.620	0.379	0.000
A30-A49 Other bacterial diseases	0.620	0.380	0.000
M45-M49 Spondylopathies	0.617	0.383	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.616	0.384	0.000
E00-E07 Disorders of thyroid gland	0.006	0.385	0.609
M19.96 Arthrosis, unspecified-Lower leg	0.606	0.394	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.603	0.397	0.000
M00-M03 Infectious arthropathies	0.602	0.398	0.000
H60-H62 Diseases of external ear	0.597	0.403	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.597	0.403	0.000
Chapter V Mental and behavioural disorders	0.596	0.404	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.595	0.405	0.000
M70-M79 Other soft tissue disorders	0.595	0.405	0.000
A41 Other septicaemia	0.594	0.406	0.000
G56 Mononeuropathies of upper limb	0.589	0.411	0.000
M54 Dorsalgia	0.588	0.412	0.000
M15 Polyarthrosis	0.588	0.412	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.588	0.412	0.000
M34 Systemic sclerosis	0.588	0.412	0.000
M33 Dermatopolymyositis	0.588	0.412	0.000
M32 Systemic lupus erythematosus	0.588	0.412	0.000
M30 Polyarteritis nodosa and related conditions	0.588	0.412	0.000
H66.9 Otitis media, unspecified	0.587	0.413	0.000
W00-W19 Falls	0.586	0.414	0.000
S60 Superficial injury of wrist and hand	0.586	0.414	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.586	0.414	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.586	0.414	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.583	0.417	0.000
T51 Toxic effect of alcohol	0.583	0.417	0.000
T79-T79 Certain early complications of trauma	0.581	0.419	0.000
M16.7 Other secondary coxarthrosis	0.580	0.420	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.579	0.421	0.000
M53 Other dorsopathies, not elsewhere classified	0.578	0.422	0.000
G90 Disorders of autonomic nervous system	0.577	0.423	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.576	0.424	0.000
M89.9 Disorder of bone, unspecified	0.573	0.427	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.571	0.429	0.000
Y52 Agents primarily affecting the cardiovascular system	0.570	0.430	0.000
M50.9 Cervical disk disorder, unspecified	0.570	0.430	0.000
M50.8 Other cervical disk disorders	0.570	0.430	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.568	0.431	0.000
M16.5 Other posttraumatic coxarthrosis	0.568	0.431	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.568	0.431	0.000
M16.3 Other dysplastic coxarthrosis	0.568	0.431	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.568	0.431	0.000
S64.1 Injury of median nerve at wrist and hand level	0.568	0.432	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.565	0.435	0.000
S90-S99 Injuries to the ankle and foot	0.564	0.435	0.000
M50.0 Cervical disk disorder with myelopathy	0.564	0.435	0.000
S61 Open wound of wrist and hand	0.564	0.435	0.000
M87 Osteonecrosis	0.564	0.436	0.000
M67 Other disorders of synovium and tendon	0.563	0.437	0.000
T91 Sequelae of injuries of neck and trunk	0.563	0.437	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.562	0.438	0.000
E04 Other non-toxic goitre	0.002	0.438	0.560
M90 Osteopathies in diseases classified elsewhere	0.560	0.440	0.000
H91 Other hearing loss	0.559	0.441	0.000
M24.1 Other articular cartilage disorders	0.558	0.441	0.000
G30-G32 Other degenerative diseases of the nervous system	0.558	0.442	0.000
M51.8 Other specified intervertebral disk disorders	0.557	0.443	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.554	0.446	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.554	0.446	0.000
S69 Other and unspecified injuries of wrist and hand	0.554	0.446	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.553	0.447	0.000
M21.3 Wrist or foot drop (acquired)	0.551	0.449	0.000
S40 Superficial injury of shoulder and upper arm	0.550	0.450	0.000
E03.8 Other specified hypothyroidism	0.002	0.450	0.548
E03.5 Myxoedema coma	0.002	0.450	0.548
E03.4 Atrophy of thyroid (acquired)	0.002	0.450	0.548
E03.3 Postinfectious hypothyroidism	0.002	0.450	0.548
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.002	0.450	0.548
E03.1 Congenital hypothyroidism without goitre	0.002	0.450	0.548
E03.0 Congenital hypothyroidism with diffuse goitre	0.002	0.450	0.548
T33-T35 Frostbite	0.549	0.450	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.549	0.450	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.549	0.450	0.000
T00-T07 Injuries involving multiple body regions	0.549	0.450	0.000
S10-S19 Injuries to the neck	0.549	0.450	0.000
M40-M43 Deforming dorsopathies	0.548	0.452	0.000
S32 Fracture of lumbar spine and pelvis	0.545	0.455	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.543	0.457	0.000
S65 Injury of blood vessels at wrist and hand level	0.543	0.457	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.542	0.458	0.000
M19.8 Other specified arthrosis	0.541	0.459	0.000
M19.2 Other secondary arthrosis	0.541	0.459	0.000
M21.2 Flexion deformity	0.541	0.459	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.541	0.459	0.000
B99-B99 Other infectious diseases	0.539	0.460	0.000
M88 Paget's disease of bone [osteitis deformans]	0.539	0.461	0.000
T66-T78 Other and unspecified effects of external causes	0.538	0.462	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.536	0.464	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.535	0.465	0.000
G95.8 Other specified diseases of spinal cord	0.534	0.465	0.000
M51.3 Other specified intervertebral disk degeneration	0.534	0.466	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.534	0.466	0.000
M51.9 Intervertebral disk disorder, unspecified	0.534	0.466	0.000
M51.4 Schmorl's nodes	0.534	0.466	0.000
H65 Nonsuppurative otitis media	0.533	0.467	0.000
M19.0 Primary arthrosis of other joints	0.532	0.467	0.000
L60-L75 Disorders of skin appendages	0.532	0.468	0.000
S50-S59 Injuries to the elbow and forearm	0.532	0.468	0.000
T90 Sequelae of injuries of head	0.532	0.468	0.000
M20.0 Deformity of finger(s)	0.532	0.468	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.531	0.468	0.000
Y44 Agents primarily affecting blood constituents	0.531	0.469	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.531	0.469	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.531	0.469	0.000
M20.3 Other deformity of hallux (acquired)	0.531	0.469	0.000
G95.9 Disease of spinal cord, unspecified	0.530	0.470	0.000
G93 Other disorders of brain	0.530	0.470	0.000
A41.8 Other specified septicaemia	0.530	0.470	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.530	0.470	0.000
G56.2 Lesion of ulnar nerve	0.529	0.471	0.000
H74 Other disorders of middle ear and mastoid	0.529	0.471	0.000
S64.3 Injury of digital nerve of thumb	0.528	0.472	0.000
M80-M85 Disorders of bone density and structure	0.526	0.473	0.001
M19.1 Posttraumatic arthrosis of other joints	0.527	0.473	0.000
M22 Disorders of patella	0.525	0.475	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.525	0.475	0.000
S70 Superficial injury of hip and thigh	0.525	0.475	0.000
S42 Fracture of shoulder and upper arm	0.525	0.475	0.000
W20-W49 Exposure to inanimate mechanical forces	0.524	0.476	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.524	0.476	0.000
M19.98 Arthrosis, unspecified (Other)	0.524	0.476	0.000
H73 Other disorders of tympanic membrane	0.523	0.477	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.522	0.478	0.000
S20-S29 Injuries to the thorax	0.522	0.478	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.521	0.479	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.519	0.480	0.000
M21.0 Valgus deformity, not elsewhere classified	0.519	0.481	0.000
B35-B49 Mycoses	0.519	0.481	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.516	0.484	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.516	0.484	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.516	0.484	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.516	0.484	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.513	0.487	0.000
M86 Osteomyelitis	0.513	0.487	0.000
V20-V29 Motorcycle rider injured in transport accident	0.512	0.488	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.511	0.489	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.511	0.489	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.511	0.489	0.000
B65-B83 Helminthiases	0.511	0.489	0.000
G70-G73 Diseases of myoneural junction and muscle	0.510	0.490	0.000
M54.1 Radiculopathy	0.510	0.490	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.510	0.490	0.000
H91.9 Hearing loss, unspecified	0.508	0.492	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.508	0.492	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.508	0.492	0.000
S68.4 Traumatic amputation of hand at wrist level	0.508	0.492	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.508	0.492	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.508	0.492	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.508	0.492	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.508	0.492	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.507	0.493	0.000
H70 Mastoiditis and related conditions	0.507	0.493	0.000
H69 Other disorders of Eustachian tube	0.507	0.493	0.000
H68 Eustachian salpingitis and obstruction	0.507	0.493	0.000
H67 Otitis media in diseases classified elsewhere	0.507	0.493	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.506	0.494	0.000
Y43 Primarily systemic agents	0.502	0.498	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.502	0.498	0.000
M18 Arthrosis of first carpometacarpal joint	0.500	0.500	0.000
M17 Gonarthrosis [arthrosis of knee]	0.499	0.501	0.000
T93 Sequelae of injuries of lower limb	0.498	0.502	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.497	0.503	0.000
E04.9 Non-toxic goitre, unspecified	0.001	0.503	0.496
T84.0 Mechanical complication of internal joint prosthesis	0.496	0.504	0.000
T51.9 Alcohol, unspecified	0.496	0.504	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.494	0.505	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.494	0.505	0.000
E07 Other disorders of thyroid	0.004	0.506	0.490
M21.9 Acquired deformity of limb, unspecified	0.493	0.506	0.000
M21.8 Other specified acquired deformities of limbs	0.493	0.506	0.000
M21.7 Unequal limb length (acquired)	0.493	0.506	0.000
M21.6 Other acquired deformities of ankle and foot	0.493	0.506	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.493	0.506	0.000
M21.4 Flat foot [pes planus] (acquired)	0.493	0.506	0.000
M79.6 Pain in limb	0.492	0.508	0.000
M62 Other disorders of muscle	0.492	0.508	0.000
Y35-Y36 Legal intervention and operations of war	0.492	0.508	0.000
Y10-Y34 Event of undetermined intent	0.492	0.508	0.000
Y00-Y09 Assault	0.492	0.508	0.000
X85-X99 Assault	0.492	0.508	0.000
X50-X57 Overexertion, travel and privation	0.492	0.508	0.000
X30-X39 Exposure to forces of nature	0.492	0.508	0.000
X20-X29 Contact with venomous animals and plants	0.492	0.508	0.000
X10-X19 Contact with heat and hot substances	0.492	0.508	0.000
X00-X09 Exposure to smoke, fire and flames	0.492	0.508	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.492	0.508	0.000
W75-W84 Other accidental threats to breathing	0.492	0.508	0.000
W65-W74 Accidental drowning and submersion	0.492	0.508	0.000
W50-W64 Exposure to animate mechanical forces	0.492	0.508	0.000
V98-V99 Other and unspecified transport accidents	0.492	0.508	0.000
V95-V97 Air and space transport accidents	0.492	0.508	0.000
V90-V94 Water transport accidents	0.492	0.508	0.000
V70-V79 Bus occupant injured in transport accident	0.492	0.508	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.492	0.508	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.492	0.508	0.000
V40-V49 Car occupant injured in transport accident	0.492	0.508	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.492	0.508	0.000
V01-V09 Pedestrian injured in transport accident	0.492	0.508	0.000
V80-V89 Other land transport accidents	0.492	0.508	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.491	0.509	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.491	0.509	0.000
M05-M14 Inflammatory polyarthropathies	0.491	0.509	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.490	0.510	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.489	0.511	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.489	0.511	0.000
G96 Other disorders of central nervous system	0.489	0.511	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.489	0.511	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.489	0.511	0.000
G92 Toxic encephalopathy	0.489	0.511	0.000
M24.9 Joint derangement, unspecified	0.488	0.512	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.488	0.512	0.000
M24.7 Protrusio acetabuli	0.488	0.512	0.000
M24.6 Ankylosis of joint	0.488	0.512	0.000
M24.5 Contracture of joint	0.488	0.512	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.488	0.512	0.000
M24.2 Disorder of ligament	0.488	0.512	0.000
M24.0 Loose body in joint	0.488	0.512	0.000
H80-H83 Diseases of inner ear	0.488	0.512	0.000
G57 Mononeuropathies of lower limb	0.487	0.513	0.000
M23 Internal derangement of knee	0.487	0.513	0.000
F25 Schizoaffective disorders	0.486	0.514	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.486	0.514	0.000
M21.1 Varus deformity, not elsewhere classified	0.484	0.516	0.000
S62 Fracture at wrist and hand level	0.483	0.517	0.000
A80-A89 Viral infections of the central nervous system	0.483	0.517	0.000
W19 Unspecified fall	0.483	0.517	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.482	0.517	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.482	0.518	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.482	0.518	0.000
B50-B64 Protozoal diseases	0.482	0.518	0.000
B15-B19 Viral hepatitis	0.482	0.518	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.482	0.518	0.000
A75-A79 Rickettsioses	0.482	0.518	0.000
A70-A74 Other diseases caused by chlamydiae	0.482	0.518	0.000
A65-A69 Other spirochaetal diseases	0.482	0.518	0.000
A20-A28 Certain zoonotic bacterial diseases	0.482	0.518	0.000
A15-A19 Tuberculosis	0.482	0.518	0.000
G50 Disorders of trigeminal nerve	0.480	0.520	0.000
T98 Sequelae of other and unspecified effects of external causes	0.480	0.520	0.000
T95 Sequelae of burns, corrosions and frostbite	0.480	0.520	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.480	0.520	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.480	0.520	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.480	0.520	0.000
T39.0 Salicylates	0.479	0.521	0.000
M48 Other spondylopathies	0.479	0.521	0.000
T51.0 Ethanol	0.479	0.521	0.000
V10-V19 Pedal cyclist injured in transport accident	0.477	0.522	0.000
H60 Otitis externa	0.477	0.522	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.477	0.523	0.000
S48 Traumatic amputation of shoulder and upper arm	0.477	0.523	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.477	0.523	0.000
S44 Injury of nerves at shoulder and upper arm level	0.477	0.523	0.000
S41 Open wound of shoulder and upper arm	0.477	0.523	0.000
S47 Crushing injury of shoulder and upper arm	0.477	0.523	0.000
T92 Sequelae of injuries of upper limb	0.477	0.523	0.000
G83 Other paralytic syndromes	0.476	0.524	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.475	0.524	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.475	0.525	0.000
F20 Schizophrenia	0.475	0.525	0.000
H92 Otalgia and effusion of ear	0.475	0.525	0.000
S32.0 Fracture of lumbar vertebra	0.474	0.526	0.000
T65 Toxic effect of other and unspecified substances	0.473	0.527	0.000
T63 Toxic effect of contact with venomous animals	0.473	0.527	0.000
T62 Toxic effect of other noxious substances eaten as food	0.473	0.527	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.473	0.527	0.000
T60 Toxic effect of pesticides	0.473	0.527	0.000
T59 Toxic effect of other gases, fumes and vapours	0.473	0.527	0.000
T57 Toxic effect of other inorganic substances	0.473	0.527	0.000
T56 Toxic effect of metals	0.473	0.527	0.000
T54 Toxic effect of corrosive substances	0.473	0.527	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.473	0.527	0.000
T52 Toxic effect of organic solvents	0.473	0.527	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.473	0.527	0.000
T58 Toxic effect of carbon monoxide	0.473	0.527	0.000
T55 Toxic effect of soaps and detergents	0.473	0.527	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.472	0.527	0.000
S64.8 Injury of other nerves at wrist and hand level	0.472	0.527	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.472	0.527	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.472	0.527	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.472	0.527	0.000
M93 Other osteochondropathies	0.472	0.528	0.000
T14 Injury of unspecified body region	0.472	0.528	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.471	0.529	0.000
M31 Other necrotising vasculopathies	0.470	0.530	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.470	0.530	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.470	0.530	0.000
M47 Spondylosis	0.470	0.530	0.000
G58 Other mononeuropathies	0.469	0.531	0.000
G54 Nerve root and plexus disorders	0.469	0.531	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.469	0.531	0.000
G52 Disorders of other cranial nerves	0.469	0.531	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.468	0.532	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.468	0.532	0.000
H71 Cholesteatoma of middle ear	0.467	0.533	0.000
S42.3 Fracture of shaft of humerus	0.466	0.533	0.000
Y57 Other and unspecified drugs and medicaments	0.466	0.533	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.466	0.534	0.000
G30 Alzheimer's disease	0.465	0.534	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.465	0.535	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.465	0.535	0.000
M66 Spontaneous rupture of synovium and tendon	0.465	0.535	0.000
Y59 Other and unspecified vaccines and biological substances	0.464	0.536	0.000
Y58 Bacterial vaccines	0.464	0.536	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.464	0.536	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.464	0.536	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.464	0.536	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.464	0.536	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.464	0.536	0.000
Y48 Anaesthetics and therapeutic gases	0.464	0.536	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.464	0.536	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.464	0.536	0.000
G95.2 Cord compression, unspecified	0.463	0.537	0.000
S60.8 Other superficial injuries of wrist and hand	0.463	0.537	0.000
M25 Other joint disorders, not elsewhere classified	0.462	0.538	0.000
M89.8 Other specified disorders of bone	0.461	0.539	0.000
M89.6 Osteopathy after poliomyelitis	0.461	0.539	0.000
M89.5 Osteolysis	0.461	0.539	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.461	0.539	0.000
M89.3 Hypertrophy of bone	0.461	0.539	0.000
M89.2 Other disorders of bone development and growth	0.461	0.539	0.000
M89.1 Epiphyseal arrest	0.461	0.539	0.000
M89.0 Algoneurodystrophy	0.461	0.539	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.461	0.539	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.461	0.539	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.461	0.539	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.461	0.539	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.461	0.539	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.461	0.539	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.461	0.539	0.000
T36 Poisoning by systemic antibiotics	0.461	0.539	0.000
G56.0 Carpal tunnel syndrome	0.460	0.540	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.459	0.541	0.000
X60-X84 Intentional self-harm	0.459	0.541	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.458	0.542	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.458	0.542	0.000
S72 Fracture of femur	0.458	0.542	0.000
S61.8 Open wound of other parts of wrist and hand	0.457	0.543	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.457	0.543	0.000
M61 Calcification and ossification of muscle	0.457	0.543	0.000
M60 Myositis	0.457	0.543	0.000
H72.0 Central perforation of tympanic membrane	0.457	0.543	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.457	0.543	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.457	0.543	0.000
M67.8 Other specified disorders of synovium and tendon	0.456	0.544	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.456	0.544	0.000
S64.4 Injury of digital nerve of other finger	0.456	0.544	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.456	0.544	0.000
H66.4 Suppurative otitis media, unspecified	0.455	0.545	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.455	0.545	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.455	0.545	0.000
H66.0 Acute suppurative otitis media	0.455	0.545	0.000
H61 Other disorders of external ear	0.455	0.545	0.000
M54.12 Radiculopathy (Cervical region)	0.455	0.545	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.453	0.547	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.453	0.547	0.000
H72.8 Other perforations of tympanic membrane	0.453	0.547	0.000
H72.2 Other marginal perforations of tympanic membrane	0.453	0.547	0.000
H72.1 Attic perforation of tympanic membrane	0.453	0.547	0.000
E04.2 Non-toxic multinodular goitre	0.001	0.547	0.452
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.453	0.547	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.452	0.547	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.452	0.548	0.000
F99-F99 Unspecified mental disorder	0.452	0.548	0.000
T91.3 Sequelae of injury of spinal cord	0.451	0.549	0.000
W18 Other fall on same level	0.451	0.549	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.450	0.550	0.000
W06 Fall involving bed	0.450	0.550	0.000
G12 Spinal muscular atrophy and related syndromes	0.449	0.550	0.000
M94 Other disorders of cartilage	0.449	0.551	0.000
M92 Other juvenile osteochondrosis	0.449	0.551	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.449	0.551	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.449	0.551	0.000
S78 Traumatic amputation of hip and thigh	0.448	0.552	0.000
S77 Crushing injury of hip and thigh	0.448	0.552	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.448	0.552	0.000
S75 Injury of blood vessels at hip and thigh level	0.448	0.552	0.000
S74 Injury of nerves at hip and thigh level	0.448	0.552	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.448	0.552	0.000
S71 Open wound of hip and thigh	0.448	0.552	0.000
Y44.2 Anticoagulants	0.448	0.552	0.000
L60 Nail disorders	0.448	0.552	0.000
M67.1 Other contracture of tendon (sheath)	0.448	0.552	0.000
G95.1 Vascular myelopathies	0.447	0.553	0.000
G95.0 Syringomyelia and syringobulbia	0.447	0.553	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.446	0.554	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.445	0.555	0.000
S37 Injury of urinary and pelvic organs	0.445	0.555	0.000
S36 Injury of intra-abdominal organs	0.445	0.555	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.445	0.555	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.445	0.555	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.445	0.555	0.000
S31 Open wound of abdomen, lower back and pelvis	0.445	0.555	0.000
B99 Other and unspecified infectious diseases	0.445	0.555	0.000
A48 Other bacterial diseases, not elsewhere classified	0.444	0.555	0.000
A44 Bartonellosis	0.444	0.555	0.000
A43 Nocardiosis	0.444	0.555	0.000
A42 Actinomycosis	0.444	0.555	0.000
A40 Streptococcal septicaemia	0.444	0.555	0.000
A39 Meningococcal infection	0.444	0.555	0.000
A37 Whooping cough	0.444	0.555	0.000
A36 Diphtheria	0.444	0.555	0.000
A32 Listeriosis	0.444	0.555	0.000
A31 Infection due to other mycobacteria	0.444	0.555	0.000
A30 Leprosy [Hansen's disease]	0.444	0.555	0.000
A46 Erysipelas	0.444	0.555	0.000
A38 Scarlet fever	0.444	0.555	0.000
A35 Other tetanus	0.444	0.555	0.000
A34 Obstetrical tetanus	0.444	0.555	0.000
A33 Tetanus neonatorum	0.444	0.555	0.000
M79.66 Pain in limb (Lower leg)	0.445	0.555	0.000
S32.4 Fracture of acetabulum	0.444	0.556	0.000
B25-B34 Other viral diseases	0.443	0.557	0.000
M49 Spondylopathies in diseases classified elsewhere	0.443	0.557	0.000
S00-S09 Injuries to the head	0.442	0.558	0.000
M99 Biomechanical lesions, not elsewhere classified	0.442	0.558	0.000
L72.1 Trichilemmal cyst	0.441	0.559	0.000
E06 Thyroiditis	0.004	0.559	0.437
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.004	0.559	0.437
E00 Congenital iodine-deficiency syndrome	0.004	0.559	0.437
E02 Subclinical iodine-deficiency hypothyroidism	0.004	0.559	0.437
S30 Superficial injury of abdomen, lower back and pelvis	0.440	0.560	0.000
H66.3 Other chronic suppurative otitis media	0.440	0.560	0.000
W29 Contact with other powered hand tools and household machinery	0.440	0.560	0.000
M87.9 Osteonecrosis, unspecified	0.439	0.561	0.000
L70 Acne	0.439	0.561	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.438	0.562	0.000
F25.9 Schizoaffective disorder, unspecified	0.438	0.562	0.000
J45 Asthma	0.002	0.562	0.436
Q00-Q07 Congenital malformations of the nervous system	0.437	0.562	0.000
S79 Other and unspecified injuries of hip and thigh	0.437	0.563	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.437	0.563	0.000
G80 Infantile cerebral palsy	0.436	0.564	0.000
M21.27 Flexion deformity (Ankle and foot)	0.436	0.564	0.000
F60-F69 Disorders of adult personality and behaviour	0.436	0.564	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.435	0.565	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.434	0.566	0.000
W07 Fall involving chair	0.434	0.566	0.000
E04.1 Non-toxic single thyroid nodule	0.001	0.567	0.432
U89 Agent resistant to other and unspecified antibiotics	0.433	0.567	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.432	0.567	0.000
Q80-Q89 Other congenital malformations	0.432	0.567	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations