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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs241418
log Bayes Factor = 13.3098
Chromosome 6   position 32,827,356  (GRCh37) Explore rs241418 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.002 0.998
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.004 0.996
M06 Other rheumatoid arthritis
0.000 0.005 0.995
Chapter II Neoplasms
0.000 0.007 0.993
M05-M14 Inflammatory polyarthropathies
0.000 0.007 0.993
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.007 0.993
C44 Other malignant neoplasms of skin
0.000 0.008 0.992
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.008 0.992
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.011 0.989
E10-E14 Diabetes mellitus
0.000 0.016 0.984
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.017 0.983
Chapter VI Diseases of the nervous system
0.000 0.018 0.982
C44.3 Skin of other and unspecified parts of face
0.000 0.018 0.982
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.019 0.981
G35 Multiple sclerosis
0.000 0.019 0.981
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.025 0.975
Chapter VII Diseases of the eye and adnexa
0.000 0.027 0.973
H30-H36 Disorders of choroid and retina
0.000 0.034 0.966
L40-L45 Papulosquamous disorders
0.000 0.039 0.961
E10 Insulin-dependent diabetes mellitus
0.000 0.039 0.961
C44.1 Skin of eyelid, including canthus
0.000 0.041 0.959
E04 Other non-toxic goitre
0.000 0.043 0.957
L60-L75 Disorders of skin appendages
0.000 0.050 0.950
L40 Psoriasis
0.000 0.060 0.940
H36 Retinal disorders in diseases classified elsewhere
0.000 0.070 0.930
C78.0 Secondary malignant neoplasm of lung
0.000 0.078 0.922
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.078 0.922
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.078 0.922
L72 Follicular cysts of skin and subcutaneous tissue
0.000 0.080 0.920
C44.7 Skin of lower limb, including hip
0.000 0.095 0.905
H36.0 Diabetic retinopathy
0.000 0.096 0.904
H35 Other retinal disorders
0.000 0.097 0.903
C44.6 Skin of upper limb, including shoulder
0.000 0.097 0.903
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.098 0.902
E04.2 Non-toxic multinodular goitre
0.000 0.099 0.901
Chapter IX Diseases of the circulatory system
0.000 0.099 0.901
L40.5 Arthropathic psoriasis
0.000 0.103 0.897
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.000 0.109 0.891
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.112 0.888
H02 Other disorders of eyelid
0.000 0.113 0.887
E10.9 Without complications
0.000 0.116 0.884
L72.1 Trichilemmal cyst
0.000 0.120 0.880
I20-I25 Ischaemic heart diseases
0.000 0.124 0.876
D60-D64 Aplastic and other anaemias
0.000 0.125 0.875
L20-L30 Dermatitis and eczema
0.000 0.127 0.873
M05 Seropositive rheumatoid arthritis
0.000 0.130 0.870
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.132 0.868
E10.3 With ophthalmic complications
0.000 0.141 0.859
L40.9 Psoriasis, unspecified
0.000 0.144 0.856
C78.7 Secondary malignant neoplasm of liver
0.000 0.145 0.855
I21 Acute myocardial infarction
0.000 0.149 0.851
H35.3 Degeneration of macula and posterior pole
0.000 0.152 0.848
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.156 0.844
M15-M19 Arthrosis
0.000 0.161 0.839
C79 Secondary malignant neoplasm of other sites
0.000 0.162 0.838
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.165 0.835
H02.1 Ectropion of eyelid
0.000 0.166 0.834
Chapter X Diseases of the respiratory system
0.000 0.173 0.827
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.173 0.826
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.175 0.825
M07 Psoriatic and enteropathic arthropathies
0.000 0.177 0.823
E04.9 Non-toxic goitre, unspecified
0.000 0.180 0.820
J30-J39 Other diseases of upper respiratory tract
0.000 0.180 0.820
E50-E64 Other nutritional deficiencies
0.000 0.187 0.813
H02.4 Ptosis of eyelid
0.000 0.189 0.811
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.000 0.194 0.806
E65-E68 Obesity and other hyperalimentation
0.000 0.195 0.805
E10.1 With ketoacidosis
0.000 0.199 0.801
J35 Chronic diseases of tonsils and adenoids
0.000 0.200 0.800
H33 Retinal detachments and breaks
0.000 0.204 0.796
E11 Non-insulin-dependent diabetes mellitus
0.000 0.204 0.796
E06 Thyroiditis
0.000 0.206 0.794
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.210 0.790
I21.9 Acute myocardial infarction, unspecified
0.000 0.214 0.786
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.215 0.785
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.218 0.782
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.218 0.782
I05-I09 Chronic rheumatic heart diseases
0.000 0.220 0.780
C73 Malignant neoplasm of thyroid gland
0.000 0.221 0.779
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.222 0.778
L71 Rosacea
0.000 0.222 0.778
J35.0 Chronic tonsillitis
0.000 0.224 0.776
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.229 0.771
E14 Unspecified diabetes mellitus
0.000 0.231 0.769
H01 Other inflammation of eyelid
0.000 0.231 0.769
M06.0 Seronegative rheumatoid arthritis
0.000 0.238 0.762
M19 Other arthrosis
0.000 0.239 0.761
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.244 0.756
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.000 0.246 0.754
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.246 0.754
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.247 0.753
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.249 0.751
L29 Pruritus
0.000 0.250 0.750
Chapter XXII Codes for special purposes
0.000 0.251 0.749
J33 Nasal polyp
0.000 0.251 0.749
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.252 0.748
M10 Gout
0.000 0.254 0.746
D00-D09 In situ neoplasms
0.000 0.255 0.745
H43-H45 Disorders of vitreous body and globe
0.000 0.256 0.744
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.000 0.256 0.744
G37 Other demyelinating diseases of central nervous system
0.000 0.259 0.741
D61 Other aplastic anaemias
0.000 0.263 0.737
L08 Other local infections of skin and subcutaneous tissue
0.000 0.265 0.735
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.267 0.733
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.268 0.732
H35.8 Other specified retinal disorders
0.000 0.272 0.728
G56 Mononeuropathies of upper limb
0.000 0.274 0.726
M18 Arthrosis of first carpometacarpal joint
0.000 0.277 0.723
H55-H59 Other disorders of eye and adnexa
0.000 0.277 0.723
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.277 0.723
H35.4 Peripheral retinal degeneration
0.000 0.279 0.721
D64 Other anaemias
0.000 0.279 0.721
G30-G32 Other degenerative diseases of the nervous system
0.000 0.282 0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.8 Other specified hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
H02.0 Entropion and trichiasis of eyelid
0.000 0.283 0.717
E13 Other specified diabetes mellitus
0.000 0.284 0.716
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.284 0.716
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.285 0.714
C81 Hodgkin's disease
0.000 0.286 0.714
C44.0 Skin of lip
0.000 0.286 0.714
L10-L14 Bullous disorders
0.000 0.286 0.714
M19.9 Arthrosis, unspecified
0.000 0.286 0.714
M06.8 Other specified rheumatoid arthritis
0.000 0.286 0.714
M06.4 Inflammatory polyarthropathy
0.000 0.286 0.714
M06.2 Rheumatoid bursitis
0.000 0.286 0.714
M06.1 Adult-onset Still's disease
0.000 0.286 0.714
C78.2 Secondary malignant neoplasm of pleura
0.000 0.286 0.713
I60-I69 Cerebrovascular diseases
0.000 0.287 0.713
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.000 0.287 0.713
M14 Arthropathies in other diseases classified elsewhere
0.000 0.288 0.712
M12 Other specific arthropathies
0.000 0.288 0.712
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.288 0.712
M08 Juvenile arthritis
0.000 0.288 0.712
C44.8 Overlapping lesion of skin
0.000 0.289 0.711
M11 Other crystal arthropathies
0.000 0.289 0.711
M00-M03 Infectious arthropathies
0.000 0.291 0.709
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.292 0.708
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.293 0.707
D62 Acute posthaemorrhagic anaemia
0.000 0.294 0.706
J32 Chronic sinusitis
0.000 0.294 0.706
E12 Malnutrition-related diabetes mellitus
0.000 0.295 0.705
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.295 0.705
G36 Other acute disseminated demyelination
0.000 0.296 0.703
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.297 0.703
G70-G73 Diseases of myoneural junction and muscle
0.000 0.298 0.702
M07.3 Other psoriatic arthropathies
0.000 0.298 0.702
G56.0 Carpal tunnel syndrome
0.000 0.299 0.701
C78.4 Secondary malignant neoplasm of small intestine
0.000 0.301 0.699
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.000 0.301 0.699
C78.1 Secondary malignant neoplasm of mediastinum
0.000 0.301 0.699
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.303 0.697
E10.4 With neurological complications
0.000 0.306 0.694
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.307 0.692
H31 Other disorders of choroid
0.000 0.307 0.692
H30 Chorioretinal inflammation
0.000 0.307 0.692
J33.0 Polyp of nasal cavity
0.000 0.309 0.691
L44 Other papulosquamous disorders
0.000 0.311 0.689
L41 Parapsoriasis
0.000 0.311 0.689
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.311 0.689
L42 Pityriasis rosea
0.000 0.311 0.689
E10.8 With unspecified complications
0.000 0.311 0.689
E10.7 With multiple complications
0.000 0.311 0.689
E10.6 With other specified complications
0.000 0.311 0.689
E10.5 With peripheral circulatory complications
0.000 0.311 0.689
E10.2 With renal complications
0.000 0.311 0.689
E10.0 With coma
0.000 0.311 0.689
C79.8 Secondary malignant neoplasm of other specified sites
0.000 0.311 0.689
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.312 0.688
C80 Malignant neoplasm without specification of site
0.000 0.314 0.686
M86-M90 Other osteopathies
0.000 0.314 0.686
E04.8 Other specified non-toxic goitre
0.000 0.314 0.686
E04.0 Non-toxic diffuse goitre
0.000 0.314 0.686
L27 Dermatitis due to substances taken internally
0.000 0.316 0.684
I25 Chronic ischaemic heart disease
0.000 0.316 0.684
H33.3 Retinal breaks without detachment
0.000 0.316 0.684
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.317 0.683
M19.90 Arthrosis, unspecified (Multiple sites)
0.000 0.319 0.681
L75 Apocrine sweat disorders
0.000 0.319 0.681
L74 Eccrine sweat disorders
0.000 0.319 0.681
L70 Acne
0.000 0.319 0.681
L68 Hypertrichosis
0.000 0.319 0.681
L67 Hair colour and hair shaft abnormalities
0.000 0.319 0.681
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.319 0.681
L64 Androgenic alopecia
0.000 0.319 0.681
L63 Alopecia areata
0.000 0.319 0.681
L62 Nail disorders in diseases classified elsewhere
0.000 0.319 0.681
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.319 0.681
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.319 0.681
H04 Disorders of lachrymal system
0.000 0.322 0.678
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.322 0.678
M60-M63 Disorders of muscles
0.000 0.322 0.678
E07 Other disorders of thyroid
0.000 0.323 0.677
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.323 0.676
E11.3 With ophthalmic complications
0.000 0.323 0.677
L40.8 Other psoriasis
0.000 0.326 0.674
L40.4 Guttate psoriasis
0.000 0.326 0.674
L40.3 Pustulosis palmaris et plantaris
0.000 0.326 0.674
L40.2 Acrodermatitis continua
0.000 0.326 0.674
L40.1 Generalised pustular psoriasis
0.000 0.326 0.674
H34 Retinal vascular occlusions
0.000 0.326 0.674
I27 Other pulmonary heart diseases
0.000 0.326 0.674
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.328 0.672
J31.0 Chronic rhinitis
0.000 0.329 0.671
M06.3 Rheumatoid nodule
0.000 0.329 0.671
G90-G99 Other disorders of the nervous system
0.000 0.329 0.670
H33.2 Serous retinal detachment
0.000 0.330 0.670
L05 Pilonidal cyst
0.000 0.333 0.667
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.333 0.666
I22 Subsequent myocardial infarction
0.000 0.334 0.666
E55 Vitamin D deficiency
0.000 0.334 0.666
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.000 0.334 0.666
D70 Agranulocytosis
0.000 0.334 0.666
E66 Obesity
0.000 0.334 0.666
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.335 0.665
J35.8 Other chronic diseases of tonsils and adenoids
0.000 0.337 0.663
D80-D89 Certain disorders involving the immune mechanism
0.000 0.337 0.663
M19.99 Arthrosis, unspecified (Site unspecified)
0.000 0.337 0.663
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.000 0.338 0.662
C83.3 Large cell (diffuse)
0.000 0.339 0.661
H05 Disorders of orbit
0.000 0.339 0.661
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.339 0.661
D55-D59 Haemolytic anaemias
0.000 0.339 0.661
E05.9 Thyrotoxicosis, unspecified
0.000 0.340 0.660
L72.2 Steatocystoma multiplex
0.000 0.340 0.660
H01.0 Blepharitis
0.000 0.340 0.659
I24 Other acute ischaemic heart diseases
0.000 0.341 0.659
E04.1 Non-toxic single thyroid nodule
0.000 0.344 0.656
L71.9 Rosacea, unspecified
0.000 0.346 0.654
H10-H13 Disorders of conjunctiva
0.000 0.347 0.653
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.348 0.652
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.348 0.652
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.349 0.651
M40-M43 Deforming dorsopathies
0.000 0.349 0.651
C92 Myeloid leukaemia
0.000 0.349 0.651
M91-M94 Chondropathies
0.000 0.349 0.650
E53 Deficiency of other B group vitamins
0.000 0.350 0.650
E14.3 With ophthalmic complications
0.000 0.350 0.650
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.350 0.650
L28 Lichen simplex chronicus and prurigo
0.000 0.351 0.649
H35.7 Separation of retinal layers
0.000 0.352 0.648
H35.2 Other proliferative retinopathy
0.000 0.352 0.648
H35.1 Retinopathy of prematurity
0.000 0.352 0.648
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.352 0.647
L04 Acute lymphadenitis
0.000 0.353 0.647
L01 Impetigo
0.000 0.353 0.647
L00 Staphylococcal scalded skin syndrome
0.000 0.353 0.647
E06.3 Autoimmune thyroiditis
0.000 0.353 0.647
I00-I02 Acute rheumatic fever
0.000 0.354 0.646
L65 Other nonscarring hair loss
0.000 0.354 0.646
L40.0 Psoriasis vulgaris
0.000 0.355 0.645
H35.9 Retinal disorder, unspecified
0.000 0.356 0.644
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.357 0.643
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.358 0.642
L43 Lichen planus
0.000 0.359 0.641
I08 Multiple valve diseases
0.000 0.361 0.639
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.361 0.639
H02.9 Disorder of eyelid, unspecified
0.000 0.362 0.638
D61.9 Aplastic anaemia, unspecified
0.000 0.362 0.638
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.362 0.638
M45-M49 Spondylopathies
0.000 0.362 0.638
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.364 0.636
C95 Leukaemia of unspecified cell type
0.000 0.364 0.636
C94 Other leukaemias of specified cell type
0.000 0.364 0.636
C93 Monocytic leukaemia
0.000 0.364 0.636
C88 Malignant immunoproliferative diseases
0.000 0.364 0.636
C86 Other specified types of T/NK-cell lymphoma
0.000 0.364 0.636
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.364 0.636
J32.0 Chronic maxillary sinusitis
0.000 0.364 0.636
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.364 0.636
H02.2 Lagophthalmos
0.000 0.364 0.636
J33.9 Nasal polyp, unspecified
0.000 0.365 0.635
I27.2 Other secondary pulmonary hypertension
0.000 0.365 0.635
C44.5 Skin of trunk
0.000 0.366 0.634
D05 Carcinoma in situ of breast
0.000 0.366 0.634
D41.4 Bladder
0.000 0.368 0.632
L60 Nail disorders
0.000 0.368 0.632
J84 Other interstitial pulmonary diseases
0.000 0.369 0.631
H02.5 Other disorders affecting eyelid function
0.000 0.370 0.630
C44.4 Skin of scalp and neck
0.000 0.370 0.630
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.370 0.630
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.371 0.629
L29.0 Pruritus ani
0.000 0.372 0.628
I23 Certain current complications following acute myocardial infarction
0.000 0.372 0.628
E11.5 With peripheral circulatory complications
0.000 0.372 0.628
H02.6 Xanthelasma of eyelid
0.000 0.372 0.628
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.373 0.627
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.373 0.627
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.374 0.626
L25 Unspecified contact dermatitis
0.000 0.374 0.626
L24 Irritant contact dermatitis
0.000 0.374 0.626
L23 Allergic contact dermatitis
0.000 0.374 0.626
L21 Seborrhoeic dermatitis
0.000 0.374 0.626
L20 Atopic dermatitis
0.000 0.374 0.626
L26 Exfoliative dermatitis
0.000 0.374 0.626
L22 Diaper [napkin] dermatitis
0.000 0.374 0.626
D45 Polycythaemia vera
0.000 0.375 0.625
M05.8 Other seropositive rheumatoid arthritis
0.000 0.376 0.624
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.376 0.624
M05.2 Rheumatoid vasculitis
0.000 0.376 0.624
M05.1 Rheumatoid lung disease
0.000 0.376 0.624
M05.0 Felty's syndrome
0.000 0.376 0.624
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.377 0.623
C74 Malignant neoplasm of adrenal gland
0.000 0.377 0.623
H02.3 Blepharochalasis
0.000 0.377 0.623
M19.93 Arthrosis, unspecified (Forearm)
0.000 0.378 0.622
M65-M68 Disorders of synovium and tendon
0.000 0.378 0.622
E66.8 Other obesity
0.000 0.381 0.619
L30 Other dermatitis
0.000 0.381 0.619
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.383 0.617
L50-L54 Urticaria and erythema
0.000 0.384 0.616
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.385 0.615
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.385 0.615
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.386 0.613
L29.9 Pruritus, unspecified
0.000 0.387 0.613
K90 Intestinal malabsorption
0.613 0.387 0.000
D46 Myelodysplastic syndromes
0.000 0.387 0.613
H35.5 Hereditary retinal dystrophy
0.000 0.387 0.613
D06 Carcinoma in situ of cervix uteri
0.000 0.387 0.613
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.387 0.612
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.388 0.612
H35.0 Background retinopathy and retinal vascular changes
0.000 0.388 0.612
G56.2 Lesion of ulnar nerve
0.000 0.388 0.612
C91 Lymphoid leukaemia
0.000 0.388 0.611
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.389 0.610
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.390 0.610
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.390 0.610
I07 Rheumatic tricuspid valve diseases
0.000 0.390 0.610
D64.9 Anaemia, unspecified
0.000 0.390 0.610
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.000 0.393 0.607
L73 Other follicular disorders
0.000 0.393 0.607
I05 Rheumatic mitral valve diseases
0.000 0.395 0.605
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.395 0.605
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.395 0.605
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.395 0.605
I30-I52 Other forms of heart disease
0.000 0.395 0.605
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.397 0.602
E11.2 With renal complications
0.000 0.398 0.602
M15 Polyarthrosis
0.000 0.399 0.601
C79.6 Secondary malignant neoplasm of ovary
0.000 0.399 0.601
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.399 0.601
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.399 0.601
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.399 0.601
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.401 0.599
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.401 0.599
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.401 0.599
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.401 0.599
H43 Disorders of vitreous body
0.000 0.402 0.598
H04.2 Epiphora
0.000 0.402 0.598
L72.0 Epidermal cyst
0.000 0.404 0.596
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.405 0.595
I67 Other cerebrovascular diseases
0.000 0.406 0.594
E05.8 Other thyrotoxicosis
0.000 0.407 0.593
E05.5 Thyroid crisis or storm
0.000 0.407 0.593
E05.4 Thyrotoxicosis factitia
0.000 0.407 0.593
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.407 0.593
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.407 0.593
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.407 0.593
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.408 0.592
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.409 0.591
M07.6 Other enteropathic arthropathies
0.000 0.410 0.590
M07.5 Arthropathy in ulcerative colitis
0.000 0.410 0.590
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.410 0.590
M07.2 Psoriatic spondylitis
0.000 0.410 0.590
M07.1 Arthritis mutilans
0.000 0.410 0.590
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.410 0.590
C81.9 Hodgkin's disease, unspecified
0.000 0.410 0.590
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.410 0.590
H53-H54 Visual disturbances and blindness
0.000 0.415 0.585
J35.1 Hypertrophy of tonsils
0.000 0.417 0.583
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.417 0.583
E63 Other nutritional deficiencies
0.000 0.417 0.583
E56 Other vitamin deficiencies
0.000 0.417 0.583
E51 Thiamine deficiency
0.000 0.417 0.583
E50 Vitamin A deficiency
0.000 0.417 0.583
E60 Dietary zinc deficiency
0.000 0.417 0.583
E59 Dietary selenium deficiency
0.000 0.417 0.583
E58 Dietary calcium deficiency
0.000 0.417 0.583
E54 Ascorbic acid deficiency
0.000 0.417 0.583
E52 Niacin deficiency [pellagra]
0.000 0.417 0.583
H55 Nystagmus and other irregular eye movements
0.000 0.417 0.583
H35.6 Retinal haemorrhage
0.000 0.418 0.582
D63.0 Anaemia in neoplastic disease
0.000 0.418 0.582
I62 Other nontraumatic intracranial haemorrhage
0.000 0.419 0.581
G91 Hydrocephalus
0.000 0.420 0.580
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.422 0.578
E67 Other hyperalimentation
0.000 0.423 0.577
E68 Sequelae of hyperalimentation
0.000 0.423 0.577
E65 Localised adiposity
0.000 0.423 0.577
J36 Peritonsillar abscess
0.000 0.425 0.575
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.000 0.426 0.574
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.000 0.426 0.574
J35.2 Hypertrophy of adenoids
0.000 0.426 0.574
E40-E46 Malnutrition
0.000 0.426 0.573
D72 Other disorders of white blood cells
0.000 0.427 0.573
M16 Coxarthrosis [arthrosis of hip]
0.000 0.428 0.572
M19.1 Posttraumatic arthrosis of other joints
0.000 0.429 0.571
G59.0 Diabetic mononeuropathy
0.000 0.429 0.571
D73 Diseases of spleen
0.000 0.429 0.571
H33.4 Traction detachment of retina
0.000 0.429 0.571
E11.8 With unspecified complications
0.000 0.429 0.571
E11.7 With multiple complications
0.000 0.429 0.571
E11.6 With other specified complications
0.000 0.429 0.571
E11.1 With ketoacidosis
0.000 0.429 0.571
E11.0 With coma
0.000 0.429 0.571
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.429 0.570
E06.9 Thyroiditis, unspecified
0.000 0.430 0.569
E06.5 Other chronic thyroiditis
0.000 0.430 0.569
E06.4 Drug-induced thyroiditis
0.000 0.430 0.569
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.430 0.569
E06.1 Subacute thyroiditis
0.000 0.430 0.569
E06.0 Acute thyroiditis
0.000 0.430 0.569
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.431 0.569
M10.9 Gout, unspecified
0.000 0.431 0.569
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.431 0.569
I50 Heart failure
0.000 0.431 0.569
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.431 0.568
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.432 0.568
I61 Intracerebral haemorrhage
0.000 0.432 0.568
C34 Malignant neoplasm of bronchus and lung
0.000 0.434 0.566
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.434 0.566
J95-J99 Other diseases of the respiratory system
0.000 0.434 0.566
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.434 0.565
J20-J22 Other acute lower respiratory infections
0.000 0.436 0.564
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.436 0.564
I20 Angina pectoris
0.000 0.437 0.563
Chapter XV Pregnancy, childbirth and the puerperium
0.000 0.438 0.562
E55.9 Vitamin D deficiency, unspecified
0.000 0.439 0.561
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.439 0.561
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.439 0.560
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.439 0.560
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.439 0.560
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.439 0.560
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.439 0.560
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.439 0.560
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.439 0.560
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.439 0.560
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.440 0.560
I09 Other rheumatic heart diseases
0.000 0.440 0.560
I06 Rheumatic aortic valve diseases
0.000 0.440 0.560
D05.1 Intraductal carcinoma in situ
0.000 0.441 0.559
J38.1 Polyp of vocal cord and larynx
0.000 0.441 0.559
M99 Biomechanical lesions, not elsewhere classified
0.000 0.442 0.558
L71.8 Other rosacea
0.000 0.442 0.557
L71.1 Rhinophyma
0.000 0.442 0.557
L71.0 Perioral dermatitis
0.000 0.442 0.557
J81 Pulmonary oedema
0.000 0.444 0.556
E11.4 With neurological complications
0.000 0.445 0.555
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.445 0.555
I50.1 Left ventricular failure
0.000 0.447 0.553
H33.0 Retinal detachment with retinal break
0.000 0.448 0.552
L05.0 Pilonidal cyst with abscess
0.000 0.448 0.552
E14.8 With unspecified complications
0.000 0.448 0.551
E14.7 With multiple complications
0.000 0.448 0.551
E14.6 With other specified complications
0.000 0.448 0.551
E14.5 With peripheral circulatory complications
0.000 0.448 0.551
E14.4 With neurological complications
0.000 0.448 0.551
E14.2 Withrenal complications
0.000 0.448 0.551
E14.1 With ketoacidosis
0.000 0.448 0.551
E14.0 With coma
0.000 0.448 0.551
H01.9 Inflammation of eyelid, unspecified
0.000 0.449 0.551
H01.8 Other specified inflammation of eyelid
0.000 0.449 0.551
H01.1 Non-infectious dermatoses of eyelid
0.000 0.449 0.551
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.451 0.549
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.000 0.453 0.547
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.453 0.546
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.453 0.546
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.453 0.546
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.453 0.546
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.453 0.546
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.453 0.546
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.453 0.546
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.453 0.546
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.453 0.546
M19.8 Other specified arthrosis
0.000 0.454 0.546
M19.2 Other secondary arthrosis
0.000 0.454 0.546
C79.2 Secondary malignant neoplasm of skin
0.000 0.454 0.545
M80-M85 Disorders of bone density and structure
0.000 0.455 0.544
M95.0 Acquired deformity of nose
0.000 0.456 0.544
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.457 0.543
G70 Myasthenia gravis and other myoneural disorders
0.000 0.457 0.542
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.458 0.542
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.458 0.542

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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