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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs259479
log Bayes Factor = 12.9589
Chromosome 1   position 218,746,640  (GRCh37) Explore rs259479 on Ensembl!
Variant rs259479 is part of Cluster X0157

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
I25 Chronic ischaemic heart disease
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
N30-N39 Other diseases of urinary system
0.992 0.008 0.000
I30-I52 Other forms of heart disease
0.990 0.010 0.000
E10-E14 Diabetes mellitus
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.986 0.014 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.984 0.016 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.978 0.022 0.000
Chapter V Mental and behavioural disorders
0.978 0.022 0.000
Y95 Nosocomial condition
0.974 0.026 0.000
Chapter VI Diseases of the nervous system
0.968 0.032 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.967 0.033 0.000
I25.1 Atherosclerotic heart disease
0.965 0.035 0.000
S60-S69 Injuries to the wrist and hand
0.956 0.044 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.955 0.045 0.000
E10 Insulin-dependent diabetes mellitus
0.954 0.046 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.952 0.048 0.000
I44 Atrioventricular and left bundle-branch block
0.950 0.050 0.000
B95-B98 Bacterial, viral and other infectious agents
0.948 0.052 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.947 0.053 0.000
N00-N08 Glomerular diseases
0.947 0.053 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.944 0.056 0.000
R30-R39 Symptoms and signs involving the urinary system
0.943 0.057 0.000
F30-F39 Mood [affective] disorders
0.943 0.057 0.000
I49 Other cardiac arrhythmias
0.936 0.064 0.000
N32 Other disorders of bladder
0.936 0.064 0.000
R39 Other symptoms and signs involving the urinary system
0.935 0.065 0.000
Y83.8 Other surgical procedures
0.929 0.071 0.000
N10-N16 Renal tubulo-interstitial diseases
0.924 0.076 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.923 0.077 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.915 0.085 0.000
S50-S59 Injuries to the elbow and forearm
0.910 0.090 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.910 0.090 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.909 0.091 0.000
I10-I15 Hypertensive diseases
0.907 0.093 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.905 0.095 0.000
I31 Other diseases of pericardium
0.905 0.095 0.000
N36 Other disorders of urethra
0.901 0.099 0.000
N03 Chronic nephritic syndrome
0.898 0.102 0.000
I21 Acute myocardial infarction
0.893 0.107 0.000
F31 Bipolar affective disorder
0.893 0.107 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.892 0.108 0.000
E10.9 Without complications
0.891 0.109 0.000
E11 Non-insulin-dependent diabetes mellitus
0.890 0.110 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.888 0.112 0.000
N30 Cystitis
0.887 0.113 0.000
S20-S29 Injuries to the thorax
0.887 0.113 0.000
S61 Open wound of wrist and hand
0.887 0.113 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.883 0.117 0.000
R31 Unspecified haematuria
0.880 0.120 0.000
Chapter VIII Diseases of the ear and mastoid process
0.877 0.123 0.000
E70-E90 Metabolic disorders
0.876 0.124 0.000
N32.3 Diverticulum of bladder
0.873 0.127 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.871 0.129 0.000
B15-B19 Viral hepatitis
0.870 0.129 0.000
G40-G47 Episodic and paroxysmal disorders
0.865 0.135 0.000
N03.9 Unspecified
0.863 0.137 0.000
R42 Dizziness and giddiness
0.858 0.142 0.000
T81 Complications of procedures, not elsewhere classified
0.856 0.144 0.000
I12 Hypertensive renal disease
0.855 0.145 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.854 0.146 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.853 0.147 0.000
R25 Abnormal involuntary movements
0.853 0.147 0.000
F31.9 Bipolar affective disorder, unspecified
0.851 0.149 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.847 0.153 0.000
E16 Other disorders of pancreatic internal secretion
0.846 0.154 0.000
I44.7 Left bundle-branch block, unspecified
0.843 0.157 0.000
F33 Recurrent depressive disorder
0.843 0.157 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.842 0.158 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.841 0.159 0.000
S64 Injury of nerves at wrist and hand level
0.841 0.159 0.000
N39 Other disorders of urinary system
0.840 0.160 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.838 0.162 0.000
G43 Migraine
0.836 0.164 0.000
I46 Cardiac arrest
0.835 0.165 0.000
E78.0 Pure hypercholesterolaemia
0.835 0.165 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.833 0.167 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.830 0.170 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.830 0.170 0.000
N32.8 Other specified disorders of bladder
0.828 0.172 0.000
I51 Complications and ill-defined descriptions of heart disease
0.827 0.173 0.000
I12.0 Hypertensive renal disease with renal failure
0.827 0.173 0.000
E50-E64 Other nutritional deficiencies
0.824 0.176 0.000
I25.2 Old myocardial infarction
0.823 0.177 0.000
H80-H83 Diseases of inner ear
0.822 0.178 0.000
S61.0 Open wound of finger(s) without damage to nail
0.821 0.179 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.821 0.179 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.819 0.181 0.000
E14 Unspecified diabetes mellitus
0.819 0.181 0.000
G43.9 Migraine, unspecified
0.816 0.184 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.816 0.184 0.000
I49.4 Other and unspecified premature depolarisation
0.816 0.184 0.000
B35-B49 Mycoses
0.815 0.185 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.814 0.186 0.000
N17-N19 Renal failure
0.813 0.187 0.000
E10.3 With ophthalmic complications
0.811 0.189 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.810 0.190 0.000
I23 Certain current complications following acute myocardial infarction
0.809 0.191 0.000
N36.8 Other specified disorders of urethra
0.809 0.191 0.000
I44.2 Atrioventricular block, complete
0.808 0.192 0.000
G90-G99 Other disorders of the nervous system
0.805 0.195 0.000
I49.8 Other specified cardiac arrhythmias
0.804 0.196 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.804 0.196 0.000
I36 Nonrheumatic tricuspid valve disorders
0.803 0.197 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.803 0.197 0.000
R39.1 Other difficulties with micturition
0.803 0.197 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.802 0.198 0.000
I44.6 Other and unspecified fascicular block
0.801 0.198 0.000
E16.2 Hypoglycaemia, unspecified
0.801 0.199 0.000
S52 Fracture of forearm
0.799 0.201 0.000
I31.3 Pericardial effusion (noninflammatory)
0.795 0.205 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.793 0.207 0.000
E11.3 With ophthalmic complications
0.793 0.207 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.792 0.208 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.790 0.210 0.000
I25.3 Aneurysm of heart
0.790 0.210 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.788 0.212 0.000
Y40 Systemic antibiotics
0.788 0.212 0.000
N39.4 Other specified urinary incontinence
0.788 0.212 0.000
I24 Other acute ischaemic heart diseases
0.785 0.215 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.785 0.215 0.000
G70-G73 Diseases of myoneural junction and muscle
0.783 0.217 0.000
N30.9 Cystitis, unspecified
0.781 0.219 0.000
E20-E35 Disorders of other endocrine glands
0.780 0.219 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.778 0.222 0.000
I22 Subsequent myocardial infarction
0.777 0.223 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.777 0.223 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.774 0.225 0.000
G20-G26 Extrapyramidal and movement disorders
0.773 0.227 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.772 0.228 0.000
H81 Disorders of vestibular function
0.771 0.229 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.770 0.230 0.000
B18 Chronic viral hepatitis
0.768 0.232 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.768 0.232 0.000
S60 Superficial injury of wrist and hand
0.766 0.234 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.764 0.236 0.000
E11.9 Without complications
0.764 0.236 0.000
R25.1 Tremor, unspecified
0.763 0.237 0.000
I31.9 Disease of pericardium, unspecified
0.762 0.238 0.000
N13 Obstructive and reflux uropathy
0.762 0.238 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.762 0.238 0.000
R34 Anuria and oliguria
0.761 0.239 0.000
I21.9 Acute myocardial infarction, unspecified
0.761 0.239 0.000
I49.0 Ventricular fibrillation and flutter
0.760 0.240 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.760 0.240 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.755 0.245 0.000
E10.1 With ketoacidosis
0.754 0.246 0.000
I47 Paroxysmal tachycardia
0.753 0.247 0.000
R79 Other abnormal findings of blood chemistry
0.753 0.247 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.752 0.247 0.000
W00-W19 Falls
0.752 0.248 0.000
O24 Diabetes mellitus in pregnancy
0.751 0.249 0.000
T66-T78 Other and unspecified effects of external causes
0.750 0.250 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.750 0.250 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.749 0.251 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.748 0.251 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.748 0.252 0.000
N30.3 Trigonitis
0.746 0.254 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.744 0.256 0.000
I25.5 Ischaemic cardiomyopathy
0.742 0.258 0.000
O20 Haemorrhage in early pregnancy
0.742 0.258 0.000
Chapter XXII Codes for special purposes
0.740 0.260 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.739 0.260 0.000
Y43 Primarily systemic agents
0.739 0.261 0.000
Y83.5 Amputation of limb(s)
0.738 0.262 0.000
Y42.5 Other oestrogens and progestogens
0.737 0.263 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.736 0.264 0.000
Chapter X Diseases of the respiratory system
0.735 0.265 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.735 0.265 0.000
N30.0 Acute cystitis
0.734 0.266 0.000
S40-S49 Injuries to the shoulder and upper arm
0.734 0.266 0.000
S50 Superficial injury of forearm
0.731 0.269 0.000
R26 Abnormalities of gait and mobility
0.731 0.269 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.730 0.270 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.728 0.272 0.000
W20-W49 Exposure to inanimate mechanical forces
0.727 0.272 0.000
E40-E46 Malnutrition
0.726 0.273 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.726 0.274 0.000
B25-B34 Other viral diseases
0.725 0.275 0.000
S10-S19 Injuries to the neck
0.725 0.275 0.000
S20 Superficial injury of thorax
0.725 0.275 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.725 0.275 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.724 0.276 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.724 0.276 0.000
S27 Injury of other and unspecified intrathoracic organs
0.723 0.276 0.000
N18 Chronic renal failure
0.723 0.277 0.000
R40 Somnolence, stupor and coma
0.723 0.277 0.000
I51.7 Cardiomegaly
0.723 0.277 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.722 0.278 0.000
H81.0 Meniere's disease
0.721 0.279 0.000
F20 Schizophrenia
0.720 0.280 0.000
N36.2 Urethral caruncle
0.720 0.280 0.000
E86 Volume depletion
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.717 0.283 0.000
N05 Unspecified nephritic syndrome
0.717 0.283 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
I25.6 Silent myocardial ischaemia
0.715 0.285 0.000
I25.4 Coronary artery aneurysm
0.715 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.715 0.285 0.000
I44.1 Atrioventricular block, second degree
0.715 0.285 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.713 0.287 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.712 0.288 0.000
F99-F99 Unspecified mental disorder
0.712 0.288 0.000
N37 Urethral disorders in diseases classified elsewhere
0.711 0.289 0.000
N34 Urethritis and urethral syndrome
0.711 0.289 0.000
N33 Bladder disorders in diseases classified elsewhere
0.711 0.289 0.000
S61.7 Multiple open wounds of wrist and hand
0.711 0.289 0.000
Y57 Other and unspecified drugs and medicaments
0.711 0.289 0.000
I52 Other heart disorders in diseases classified elsewhere
0.710 0.290 0.000
I48 Atrial fibrillation and flutter
0.710 0.290 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.710 0.290 0.000
I41 Myocarditis in diseases classified elsewhere
0.710 0.290 0.000
I40 Acute myocarditis
0.710 0.290 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.710 0.290 0.000
I37 Pulmonary valve disorders
0.710 0.290 0.000
I32 Pericarditis in diseases classified elsewhere
0.710 0.290 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.710 0.290 0.000
N02 Recurrent and persistent haematuria
0.709 0.291 0.000
F03 Unspecified dementia
0.709 0.291 0.000
S61.1 Open wound of finger(s) with damage to nail
0.709 0.291 0.000
N04 Nephrotic syndrome
0.709 0.291 0.000
E13 Other specified diabetes mellitus
0.708 0.292 0.000
E12 Malnutrition-related diabetes mellitus
0.708 0.292 0.000
I49.5 Sick sinus syndrome
0.707 0.293 0.000
B99-B99 Other infectious diseases
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.293 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A80-A89 Viral infections of the central nervous system
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
Y42.7 Androgens and anabolic congeners
0.706 0.294 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.706 0.294 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.706 0.294 0.000
Y98 Lifestyle-related condition
0.706 0.294 0.000
Y97 Environmental-pollution-related condition
0.706 0.294 0.000
Y96 Work-related condition
0.706 0.294 0.000
I46.9 Cardiac arrest, unspecified
0.705 0.295 0.000
E14.9 Without complications
0.705 0.295 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.705 0.295 0.000
S90-S99 Injuries to the ankle and foot
0.705 0.295 0.000
I49.9 Cardiac arrhythmia, unspecified
0.704 0.296 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.704 0.296 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.701 0.299 0.000
F80-F89 Disorders of psychological development
0.701 0.299 0.000
F70-F79 Mental retardation
0.701 0.299 0.000
F60-F69 Disorders of adult personality and behaviour
0.701 0.299 0.000
S51 Open wound of forearm
0.700 0.300 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.700 0.300 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.700 0.300 0.000
N25-N29 Other disorders of kidney and ureter
0.700 0.300 0.000
N99-N99 Other disorders of the genitourinary system
0.700 0.300 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.700 0.300 0.000
N39.8 Other specified disorders of urinary system
0.699 0.301 0.000
N32.1 Vesicointestinal fistula
0.698 0.302 0.000
I30 Acute pericarditis
0.697 0.303 0.000
S64.4 Injury of digital nerve of other finger
0.697 0.303 0.000
S70-S79 Injuries to the hip and thigh
0.696 0.304 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.696 0.304 0.000
B18.2 Chronic viral hepatitis C
0.695 0.305 0.000
Y59 Other and unspecified vaccines and biological substances
0.693 0.307 0.000
Y58 Bacterial vaccines
0.693 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.693 0.307 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.693 0.307 0.000
Y52 Agents primarily affecting the cardiovascular system
0.693 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.693 0.307 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.693 0.307 0.000
Y48 Anaesthetics and therapeutic gases
0.693 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.693 0.307 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.693 0.307 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
S52.5 Fracture of lower end of radius
0.693 0.307 0.000
G30-G32 Other degenerative diseases of the nervous system
0.691 0.309 0.000
I47.2 Ventricular tachycardia
0.688 0.312 0.000
N11 Chronic tubulo-interstitial nephritis
0.688 0.312 0.000
R25.3 Fasciculation
0.687 0.313 0.000
Y84.0 Cardiac catheterisation
0.687 0.313 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.685 0.315 0.000
S67 Crushing injury of wrist and hand
0.685 0.315 0.000
S65 Injury of blood vessels at wrist and hand level
0.685 0.315 0.000
E10.4 With neurological complications
0.685 0.315 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.685 0.315 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.684 0.316 0.000
E11.4 With neurological complications
0.684 0.316 0.000
E10.8 With unspecified complications
0.684 0.316 0.000
E10.7 With multiple complications
0.684 0.316 0.000
E10.6 With other specified complications
0.684 0.316 0.000
E10.5 With peripheral circulatory complications
0.684 0.316 0.000
E10.2 With renal complications
0.684 0.316 0.000
E10.0 With coma
0.684 0.316 0.000
F33.9 Recurrent depressive disorder, unspecified
0.683 0.317 0.000
G40 Epilepsy
0.683 0.317 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.683 0.317 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.683 0.317 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.683 0.317 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.683 0.317 0.000
Y83.0 Surgical operation with transplant of whole organ
0.682 0.318 0.000
L50-L54 Urticaria and erythema
0.681 0.318 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.681 0.319 0.000
I44.5 Left posterior fascicular block
0.681 0.319 0.000
I44.4 Left anterior fascicular block
0.681 0.319 0.000
I44.3 Other and unspecified atrioventricular block
0.681 0.319 0.000
H83 Other diseases of inner ear
0.681 0.319 0.000
R25.2 Cramp and spasm
0.680 0.320 0.000
T87 Complications peculiar to reattachment and amputation
0.679 0.321 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.679 0.321 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.679 0.321 0.000
N06 Isolated proteinuria with specified morphological lesion
0.679 0.321 0.000
N01 Rapidly progressive nephritic syndrome
0.679 0.321 0.000
N00 Acute nephritic syndrome
0.679 0.321 0.000
F41 Other anxiety disorders
0.677 0.323 0.000
R73 Elevated blood glucose level
0.677 0.323 0.000
O85-O92 Complications predominantly related to the puerperium
0.677 0.323 0.000
R36 Urethral discharge
0.676 0.324 0.000
F38 Other mood [affective] disorders
0.676 0.324 0.000
F34 Persistent mood [affective] disorders
0.676 0.324 0.000
F30 Manic episode
0.676 0.324 0.000
F39 Unspecified mood [affective] disorder
0.676 0.324 0.000
Y83.3 Surgical operation with formation of external stoma
0.675 0.325 0.000
I23.8 Other current complications following acute myocardial infarction
0.673 0.327 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.672 0.327 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.672 0.328 0.000
B17 Other acute viral hepatitis
0.672 0.328 0.000
I49.2 Junctional premature depolarisation
0.671 0.329 0.000
I49.1 Atrial premature depolarisation
0.671 0.329 0.000
I05-I09 Chronic rheumatic heart diseases
0.671 0.329 0.000
N32.4 Rupture of bladder, nontraumatic
0.671 0.329 0.000
N32.2 Vesical fistula, not elsewhere classified
0.671 0.329 0.000
Y83.9 Surgical procedure, unspecified
0.671 0.329 0.000
R39.2 Extrarenal uraemia
0.670 0.329 0.000
R39.0 Extravasation of urine
0.670 0.329 0.000
I33 Acute and subacute endocarditis
0.670 0.330 0.000
S69 Other and unspecified injuries of wrist and hand
0.670 0.330 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.669 0.330 0.000
S52.6 Fracture of lower end of both ulna and radius
0.669 0.331 0.000
G61 Inflammatory polyneuropathy
0.669 0.331 0.000
E55 Vitamin D deficiency
0.669 0.331 0.000
T86 Failure and rejection of transplanted organs and tissues
0.669 0.331 0.000
R30 Pain associated with micturition
0.668 0.332 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.666 0.334 0.000
T17 Foreign body in respiratory tract
0.666 0.334 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.663 0.336 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.663 0.337 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.662 0.338 0.000
N15 Other renal tubulo-interstitial diseases
0.662 0.338 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.662 0.338 0.000
N10 Acute tubulo-interstitial nephritis
0.662 0.338 0.000
X60-X84 Intentional self-harm
0.661 0.339 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.658 0.342 0.000
N60-N64 Disorders of breast
0.658 0.342 0.000
I44.0 Atrioventricular block, first degree
0.658 0.342 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.658 0.342 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.657 0.343 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.656 0.344 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.656 0.344 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.656 0.344 0.000
A30-A49 Other bacterial diseases
0.655 0.344 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.655 0.345 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.653 0.347 0.000
S59 Other and unspecified injuries of forearm
0.652 0.347 0.000
S58 Traumatic amputation of forearm
0.652 0.347 0.000
S57 Crushing injury of forearm
0.652 0.347 0.000
S56 Injury of muscle and tendon at forearm level
0.652 0.347 0.000
S55 Injury of blood vessels at forearm level
0.652 0.347 0.000
S54 Injury of nerves at forearm level
0.652 0.347 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.652 0.347 0.000
E15 Nondiabetic hypoglycaemic coma
0.652 0.348 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.652 0.348 0.000
S32 Fracture of lumbar spine and pelvis
0.650 0.350 0.000
I15 Secondary hypertension
0.650 0.350 0.000
I13 Hypertensive heart and renal disease
0.650 0.350 0.000
I11 Hypertensive heart disease
0.650 0.350 0.000
I31.8 Other specified diseases of pericardium
0.649 0.351 0.000
I31.2 Haemopericardium, not elsewhere classified
0.649 0.351 0.000
I31.1 Chronic constrictive pericarditis
0.649 0.351 0.000
I31.0 Chronic adhesive pericarditis
0.649 0.351 0.000
O23 Infections of genito-urinary tract in pregnancy
0.649 0.351 0.000
H65-H75 Diseases of middle ear and mastoid
0.648 0.352 0.000
B35 Dermatophytosis
0.648 0.352 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.647 0.353 0.000
N36.9 Urethral disorder, unspecified
0.646 0.354 0.000
N36.3 Prolapsed urethral mucosa
0.646 0.354 0.000
N36.1 Urethral diverticulum
0.646 0.354 0.000
N36.0 Urethral fistula
0.646 0.354 0.000
A00-A09 Intestinal infectious diseases
0.645 0.355 0.000
I50 Heart failure
0.644 0.356 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.644 0.356 0.000
T81.9 Unspecified complication of procedure
0.644 0.356 0.000
N03.8 Other
0.644 0.356 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.644 0.356 0.000
N03.6 Dense deposit disease
0.644 0.356 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.644 0.356 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.644 0.356 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.644 0.356 0.000
N03.2 Diffuse membranous glomerulonephritis
0.644 0.356 0.000
N03.1 Focal and segmental glomerular lesions
0.644 0.356 0.000
N03.0 Minor glomerular abnormality
0.644 0.356 0.000
Y83.4 Other reconstructive surgery
0.643 0.357 0.000
J60-J70 Lung diseases due to external agents
0.643 0.357 0.000
E78.2 Mixed hyperlipidaemia
0.643 0.357 0.000
Y84.2 Radiological procedure and radiotherapy
0.642 0.358 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.642 0.358 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.642 0.358 0.000
I24.8 Other forms of acute ischaemic heart disease
0.641 0.359 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.640 0.360 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.640 0.360 0.000
N39.0 Urinary tract infection, site not specified
0.640 0.360 0.000
V10-V19 Pedal cyclist injured in transport accident
0.640 0.360 0.000
F31.8 Other bipolar affective disorders
0.640 0.360 0.000
F31.7 Bipolar affective disorder, currently in remission
0.640 0.360 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.640 0.360 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.640 0.360 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.640 0.360 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.640 0.360 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.640 0.360 0.000
B49 Unspecified mycosis
0.640 0.360 0.000
R46 Symptoms and signs involving appearance and behaviour
0.640 0.360 0.000
R43 Disturbances of smell and taste
0.640 0.360 0.000
N30.1 Interstitial cystitis (chronic)
0.639 0.360 0.000
N40-N51 Diseases of male genital organs
0.639 0.361 0.000
E11.8 With unspecified complications
0.638 0.362 0.000
E11.7 With multiple complications
0.638 0.362 0.000
E11.6 With other specified complications
0.638 0.362 0.000
E11.1 With ketoacidosis
0.638 0.362 0.000
E11.0 With coma
0.638 0.362 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.637 0.363 0.000
I27 Other pulmonary heart diseases
0.637 0.363 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.637 0.363 0.000
S64.3 Injury of digital nerve of thumb
0.637 0.363 0.000
N30.4 Irradiation cystitis
0.636 0.364 0.000
S29 Other and unspecified injuries of thorax
0.636 0.364 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.636 0.364 0.000
S26 Injury of heart
0.636 0.364 0.000
S25 Injury of blood vessels of thorax
0.636 0.364 0.000
S24 Injury of nerves and spinal cord at thorax level
0.636 0.364 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.636 0.364 0.000
S21 Open wound of thorax
0.636 0.364 0.000
E53 Deficiency of other B group vitamins
0.636 0.364 0.000
G93 Other disorders of brain
0.635 0.365 0.000
B07 Viral warts
0.634 0.366 0.000
Y65 Other misadventures during surgical and medical care
0.634 0.366 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.634 0.366 0.000
I46.0 Cardiac arrest with successful resuscitation
0.634 0.366 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.633 0.367 0.000
O29 Complications of anaesthesia during pregnancy
0.633 0.367 0.000
O28 Abnormal findings on antenatal screening of mother
0.633 0.367 0.000
O22 Venous complications in pregnancy
0.633 0.367 0.000
O21 Excessive vomiting in pregnancy
0.633 0.367 0.000
O25 Malnutrition in pregnancy
0.633 0.367 0.000
T31 Burns classified according to extent of body surface involved
0.632 0.368 0.000
O20.0 Threatened abortion
0.631 0.369 0.000
Y44 Agents primarily affecting blood constituents
0.631 0.369 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.630 0.370 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.630 0.370 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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