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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2736177
log Bayes Factor = 114.154
Chromosome 6   position 31,586,094  (GRCh37) Explore rs2736177 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
# Top node
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.001 0.999
H36.0 Diabetic retinopathy
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
E83.1 Disorders of iron metabolism
0.997 0.003 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.004 0.996
I20.9 Angina pectoris, unspecified
0.000 0.005 0.995
E14.9 Without complications
0.000 0.005 0.995
E10.4 With neurological complications
0.000 0.006 0.994
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.006 0.994
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
I25.1 Atherosclerotic heart disease
0.000 0.007 0.993
E70-E90 Metabolic disorders
0.000 0.008 0.992
L43 Lichen planus
0.000 0.008 0.992
H43-H45 Disorders of vitreous body and globe
0.000 0.010 0.990
I22 Subsequent myocardial infarction
0.000 0.010 0.990
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.010 0.990
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.010 0.990
H43 Disorders of vitreous body
0.000 0.012 0.988
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.013 0.987
L43.9 Lichen planus, unspecified
0.000 0.014 0.986
Chapter VI Diseases of the nervous system
0.983 0.017 0.000
E14.3 With ophthalmic complications
0.000 0.018 0.982
E16 Other disorders of pancreatic internal secretion
0.000 0.018 0.982
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.020 0.980
G20-G26 Extrapyramidal and movement disorders
0.978 0.022 0.000
H43.8 Other disorders of vitreous body
0.000 0.022 0.978
M45-M49 Spondylopathies
0.000 0.022 0.978
E16.2 Hypoglycaemia, unspecified
0.000 0.023 0.977
M45 Ankylosing spondylitis
0.000 0.024 0.976
I25.5 Ischaemic cardiomyopathy
0.000 0.024 0.976
G20 Parkinson's disease
0.976 0.024 0.000
I20.0 Unstable angina
0.000 0.026 0.974
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.027 0.973
M70-M79 Other soft tissue disorders
0.000 0.034 0.966
J45.9 Asthma, unspecified
0.000 0.036 0.964
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.041 0.959
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.049 0.951
H43.3 Other vitreous opacities
0.000 0.058 0.942
E07 Other disorders of thyroid
0.000 0.058 0.942
H35 Other retinal disorders
0.000 0.068 0.932
H34 Retinal vascular occlusions
0.000 0.071 0.929
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.078 0.922
I24 Other acute ischaemic heart diseases
0.000 0.078 0.921
M75 Shoulder lesions
0.000 0.082 0.918
M05 Seropositive rheumatoid arthritis
0.000 0.092 0.908
I25.2 Old myocardial infarction
0.000 0.092 0.908
G37.8 Other specified demyelinating diseases of central nervous system
0.904 0.096 0.000
H35.8 Other specified retinal disorders
0.000 0.097 0.903
I30-I52 Other forms of heart disease
0.000 0.098 0.902
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.099 0.901
I15 Secondary hypertension
0.000 0.099 0.901
M75.0 Adhesive capsulitis of shoulder
0.000 0.099 0.901
I47 Paroxysmal tachycardia
0.000 0.100 0.900
E78.2 Mixed hyperlipidaemia
0.000 0.102 0.898
I12 Hypertensive renal disease
0.000 0.102 0.898
E07.9 Disorder of thyroid, unspecified
0.000 0.104 0.896
E13 Other specified diabetes mellitus
0.000 0.107 0.893
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.113 0.887
E11.3 With ophthalmic complications
0.000 0.116 0.884
I47.1 Supraventricular tachycardia
0.000 0.116 0.884
M07 Psoriatic and enteropathic arthropathies
0.000 0.118 0.882
E10.5 With peripheral circulatory complications
0.000 0.124 0.876
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.127 0.873
M77 Other enthesopathies
0.000 0.134 0.866
K90 Intestinal malabsorption
0.000 0.136 0.864
E11.1 With ketoacidosis
0.000 0.138 0.862
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.139 0.861
I35 Nonrheumatic aortic valve disorders
0.000 0.140 0.860
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.140 0.860
I35.0 Aortic (valve) stenosis
0.000 0.142 0.858
E78.8 Other disorders of lipoprotein metabolism
0.000 0.145 0.855
H34.8 Other retinal vascular occlusions
0.000 0.146 0.854
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.152 0.848
E11.2 With renal complications
0.000 0.153 0.847
I12.9 Hypertensive renal disease without renal failure
0.000 0.153 0.847
E10.2 With renal complications
0.000 0.155 0.845
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.157 0.843
G30-G32 Other degenerative diseases of the nervous system
0.840 0.160 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.161 0.839
I51 Complications and ill-defined descriptions of heart disease
0.000 0.164 0.836
I20.1 Angina pectoris with documented spasm
0.000 0.165 0.835
G40-G47 Episodic and paroxysmal disorders
0.831 0.169 0.000
M06.3 Rheumatoid nodule
0.000 0.169 0.831
I15.1 Hypertension secondary to other renal disorders
0.000 0.171 0.829
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.174 0.826
K90-K93 Other diseases of the digestive system
0.000 0.177 0.823
Chapter XI Diseases of the digestive system
0.000 0.180 0.820
I51.8 Other ill-defined heart diseases
0.000 0.180 0.820
E83 Disorders of mineral metabolism
0.766 0.182 0.051
E13.9 Without complications
0.000 0.183 0.817
K70-K77 Diseases of liver
0.000 0.185 0.815
M77.1 Lateral epicondylitis
0.000 0.186 0.814
E11.0 With coma
0.000 0.189 0.811
K74 Fibrosis and cirrhosis of liver
0.000 0.189 0.811
G00-G09 Inflammatory diseases of the central nervous system
0.803 0.197 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.197 0.803
M70.4 Prepatellar bursitis
0.000 0.198 0.802
K74.3 Primary biliary cirrhosis
0.000 0.199 0.801
M07.3 Other psoriatic arthropathies
0.000 0.201 0.799
L43.8 Other lichen planus
0.000 0.205 0.795
M75.2 Bicipital tendinitis
0.000 0.207 0.793
I47.2 Ventricular tachycardia
0.000 0.212 0.788
M65-M68 Disorders of synovium and tendon
0.000 0.213 0.787
M11 Other crystal arthropathies
0.000 0.213 0.786
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.214 0.786
L40.8 Other psoriasis
0.000 0.215 0.785
H43.9 Disorder of vitreous body, unspecified
0.000 0.216 0.784
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.222 0.778
E74 Other disorders of carbohydrate metabolism
0.000 0.222 0.778
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.222 0.778
G25 Other extrapyramidal and movement disorders
0.776 0.224 0.000
E11.5 With peripheral circulatory complications
0.000 0.224 0.776
M75.3 Calcific tendinitis of shoulder
0.000 0.224 0.776
I25.3 Aneurysm of heart
0.000 0.225 0.775
K72 Hepatic failure, not elsewhere classified
0.000 0.236 0.764
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.236 0.764
H35.4 Peripheral retinal degeneration
0.000 0.239 0.761
G80-G83 Cerebral palsy and other paralytic syndromes
0.761 0.239 0.000
E78.4 Other hyperlipidaemia
0.000 0.240 0.760
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.240 0.760
E06 Thyroiditis
0.000 0.250 0.750
E03.8 Other specified hypothyroidism
0.000 0.252 0.748
I23 Certain current complications following acute myocardial infarction
0.000 0.255 0.745
E78.1 Pure hyperglyceridaemia
0.000 0.256 0.744
H35.2 Other proliferative retinopathy
0.000 0.256 0.743
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.257 0.743
E40-E46 Malnutrition
0.000 0.258 0.742
H35.6 Retinal haemorrhage
0.000 0.260 0.740
G46 Vascular syndromes of brain in cerebrovascular diseases
0.737 0.263 0.000
E14.4 With neurological complications
0.000 0.264 0.735
M46 Other inflammatory spondylopathies
0.000 0.265 0.735
H34.2 Other retinal artery occlusions
0.000 0.266 0.734
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.266 0.734
E05.9 Thyrotoxicosis, unspecified
0.000 0.266 0.734
I46 Cardiac arrest
0.000 0.271 0.729
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.727 0.273 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.276 0.724
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.280 0.719
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H30 Chorioretinal inflammation
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
H35.5 Hereditary retinal dystrophy
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
L42 Pityriasis rosea
0.000 0.285 0.715
E78.6 Lipoprotein deficiency
0.000 0.286 0.714
E78.3 Hyperchylomicronaemia
0.000 0.286 0.714
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.286 0.714
I21 Acute myocardial infarction
0.000 0.287 0.713
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.287 0.713
M14 Arthropathies in other diseases classified elsewhere
0.000 0.287 0.712
K74.5 Biliary cirrhosis, unspecified
0.000 0.288 0.712
E79 Disorders of purine and pyrimidine metabolism
0.000 0.288 0.711
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.711
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.711
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.711
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.711
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.711
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.711
L43.3 Subacute (active) lichen planus
0.000 0.288 0.711
L43.2 Lichenoid drug reaction
0.000 0.288 0.711
L43.1 Bullous lichen planus
0.000 0.288 0.711
L43.0 Hypertrophic lichen planus
0.000 0.288 0.711
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.290 0.710
E15 Nondiabetic hypoglycaemic coma
0.000 0.290 0.710
M65 Synovitis and tenosynovitis
0.000 0.291 0.709
H43.2 Crystalline deposits in vitreous body
0.000 0.291 0.709
H43.0 Vitreous prolapse
0.000 0.291 0.709
L40.0 Psoriasis vulgaris
0.000 0.294 0.706
G47 Sleep disorders
0.706 0.294 0.000
H34.1 Central retinal artery occlusion
0.000 0.295 0.705
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.296 0.704
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.296 0.704
E16.4 Abnormal secretion of gastrin
0.000 0.296 0.704
E16.3 Increased secretion of glucagon
0.000 0.296 0.704
E16.1 Other hypoglycaemia
0.000 0.296 0.704
M49 Spondylopathies in diseases classified elsewhere
0.000 0.297 0.703
G23 Other degenerative diseases of basal ganglia
0.701 0.298 0.000
G21 Secondary Parkinsonism
0.701 0.298 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.701 0.298 0.000
G22 Parkinsonism in diseases classified elsewhere
0.701 0.298 0.000
E83.3 Disorders of phosphorus metabolism
0.686 0.299 0.015
G30 Alzheimer's disease
0.701 0.299 0.000
K74.6 Other and unspecified cirrhosis of liver
0.000 0.299 0.701
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.300 0.700
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.300 0.700
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.300 0.700
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.300 0.700
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.300 0.700
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.300 0.700
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.300 0.700
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.300 0.700
E07.8 Other specified disorders of thyroid
0.000 0.301 0.698
M91-M94 Chondropathies
0.000 0.303 0.697
E11.8 With unspecified complications
0.000 0.304 0.696
I47.0 Reentry ventricular arrhythmia
0.000 0.304 0.696
M06.34 Rheumatoid nodule (Hand)
0.000 0.305 0.695
I11 Hypertensive heart disease
0.000 0.305 0.695
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.307 0.693
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.309 0.691
K72.9 Hepatic failure, unspecified
0.000 0.311 0.689
G41 Status epilepticus
0.686 0.314 0.000
K73 Chronic hepatitis, not elsewhere classified
0.000 0.319 0.680
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.320 0.680
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.678 0.322 0.000
I51.9 Heart disease, unspecified
0.000 0.324 0.676
E07.1 Dyshormogenetic goitre
0.000 0.325 0.675
E07.0 Hypersecretion of calcitonin
0.000 0.325 0.675
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.326 0.674
M77.5 Other enthesopathy of foot
0.000 0.326 0.673
E14.6 With other specified complications
0.000 0.330 0.669
G44 Other headache syndromes
0.669 0.331 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.331 0.669
M71 Other bursopathies
0.000 0.331 0.668
M06.4 Inflammatory polyarthropathy
0.000 0.332 0.668
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.332 0.668
H35.1 Retinopathy of prematurity
0.000 0.332 0.668
M75.4 Impingement syndrome of shoulder
0.000 0.334 0.666
H34.0 Transient retinal artery occlusion
0.000 0.334 0.666
H31 Other disorders of choroid
0.000 0.335 0.664
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.663 0.337 0.000
I51.0 Cardiac septal defect, acquired
0.000 0.339 0.661
M12 Other specific arthropathies
0.000 0.339 0.661
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.340 0.660
K51.9 Ulcerative colitis, unspecified
0.659 0.341 0.000
K72.0 Acute and subacute hepatic failure
0.000 0.342 0.658
M75.8 Other shoulder lesions
0.000 0.342 0.658
G09 Sequelae of inflammatory diseases of central nervous system
0.656 0.344 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.344 0.656
K51 Ulcerative colitis
0.654 0.345 0.001
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.345 0.655
L40.3 Pustulosis palmaris et plantaris
0.000 0.346 0.654
M05.8 Other seropositive rheumatoid arthritis
0.000 0.349 0.651
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.349 0.651
M05.2 Rheumatoid vasculitis
0.000 0.349 0.651
M05.1 Rheumatoid lung disease
0.000 0.349 0.651
M05.0 Felty's syndrome
0.000 0.349 0.651
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.349 0.651
I31 Other diseases of pericardium
0.000 0.350 0.650
E11.6 With other specified complications
0.000 0.351 0.649
M06.0 Seronegative rheumatoid arthritis
0.000 0.351 0.649
H34.9 Retinal vascular occlusion, unspecified
0.000 0.351 0.649
H35.7 Separation of retinal layers
0.000 0.351 0.649
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.351 0.649
I52 Other heart disorders in diseases classified elsewhere
0.000 0.353 0.646
I48 Atrial fibrillation and flutter
0.000 0.353 0.646
I41 Myocarditis in diseases classified elsewhere
0.000 0.353 0.646
I40 Acute myocarditis
0.000 0.353 0.646
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.353 0.646
I32 Pericarditis in diseases classified elsewhere
0.000 0.353 0.646
I15.9 Seconday hypertension, unspecified
0.000 0.354 0.646
I15.8 Other secondary hypertension
0.000 0.354 0.646
I15.2 Hypertension secondary to endocrine disorders
0.000 0.354 0.646
I15.0 Renovascular hypertension
0.000 0.354 0.646
I51.6 Cardiovascular disease, unspecified
0.000 0.354 0.646
E84 Cystic fibrosis
0.001 0.357 0.643
K51.3 Ulcerative (chronic) rectosigmoiditis
0.642 0.357 0.000
I25.4 Coronary artery aneurysm
0.000 0.359 0.641
E13.8 With unspecified complications
0.000 0.359 0.641
E13.7 With multiple complications
0.000 0.359 0.641
E13.6 With other specified complications
0.000 0.359 0.641
E13.5 With peripheral circulatory complications
0.000 0.359 0.641
E13.4 With neurological complications
0.000 0.359 0.641
E13.3 With ophthalmic complications
0.000 0.359 0.641
E13.2 With renal complications
0.000 0.359 0.641
E13.1 With ketoacidosis
0.000 0.359 0.641
E13.0 With coma
0.000 0.359 0.641
G40 Epilepsy
0.640 0.360 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.361 0.639
G46.7 Other lacunar syndromes
0.638 0.362 0.000
M11.2 Other chondrocalcinosis
0.000 0.366 0.634
G00 Bacterial meningitis, not elsewhere classified
0.634 0.366 0.000
I44 Atrioventricular and left bundle-branch block
0.000 0.367 0.633
M07.6 Other enteropathic arthropathies
0.000 0.367 0.633
M07.5 Arthropathy in ulcerative colitis
0.000 0.367 0.633
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.367 0.633
M07.2 Psoriatic spondylitis
0.000 0.367 0.633
M07.1 Arthritis mutilans
0.000 0.367 0.633
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.367 0.633
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.369 0.631
M77.0 Medial epicondylitis
0.000 0.370 0.630
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.371 0.629
M70.7 Other bursitis of hip
0.000 0.371 0.628
E89.3 Postprocedural hypopituitarism
0.000 0.372 0.628
L10-L14 Bullous disorders
0.000 0.373 0.627
M70.5 Other bursitis of knee
0.000 0.374 0.626
I22.8 Subsequent myocardial infarction of other sites
0.000 0.375 0.625
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.375 0.624
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.378 0.622
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.378 0.621
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.379 0.621
M77.3 Calcaneal spur
0.000 0.379 0.621
M77.2 Periarthritis of wrist
0.000 0.379 0.621
E83.5 Disorders of calcium metabolism
0.616 0.380 0.004
G81 Hemiplegia
0.620 0.380 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.381 0.619
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.381 0.619
K90.1 Tropical sprue
0.000 0.381 0.619
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.383 0.617
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.383 0.617
M70.1 Bursitis of hand
0.000 0.383 0.617
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.383 0.617
G31.9 Degenerative disease of nervous system, unspecified
0.617 0.383 0.000
I46.9 Cardiac arrest, unspecified
0.000 0.386 0.614
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.387 0.612
G03 Meningitis due to other and unspecified causes
0.611 0.388 0.000
E06.3 Autoimmune thyroiditis
0.000 0.390 0.610
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.390 0.610
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.391 0.609
E05.5 Thyroid crisis or storm
0.000 0.392 0.608
E05.4 Thyrotoxicosis factitia
0.000 0.392 0.608
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.392 0.608
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.392 0.608
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.392 0.607
H43.1 Vitreous haemorrhage
0.000 0.393 0.607
K90.9 Intestinal malabsorption, unspecified
0.000 0.393 0.607
G90-G99 Other disorders of the nervous system
0.606 0.394 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.396 0.604
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.396 0.604
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.396 0.604
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.396 0.604
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.396 0.604
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.396 0.604
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.396 0.604
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.396 0.604
G06 Intracranial and intraspinal abscess and granuloma
0.604 0.396 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.602 0.398 0.000
E88 Other metabolic disorders
0.000 0.399 0.601
I35.8 Other aortic valve disorders
0.000 0.400 0.600
I51.5 Myocardial degeneration
0.000 0.400 0.600
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.400 0.600
G83 Other paralytic syndromes
0.600 0.400 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.600 0.400 0.000
H35.9 Retinal disorder, unspecified
0.000 0.401 0.599
G25.8 Other specified extrapyramidal and movement disorders
0.598 0.402 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.404 0.596
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.404 0.596
M06.38 Rheumatoid nodule (Other)
0.000 0.404 0.596
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.404 0.596
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.404 0.596
M06.33 Rheumatoid nodule (Forearm)
0.000 0.404 0.596
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.404 0.596
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.404 0.596
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.404 0.596
G25.9 Extrapyramidal and movement disorder, unspecified
0.596 0.404 0.000
G46.4 Cerebellar stroke syndrome
0.595 0.405 0.000
M70.6 Trochanteric bursitis
0.000 0.406 0.594
M00-M03 Infectious arthropathies
0.000 0.407 0.592
G47.8 Other sleep disorders
0.593 0.407 0.000
M94 Other disorders of cartilage
0.000 0.408 0.592
M75.9 Shoulder lesion, unspecified
0.000 0.408 0.592
M79.7 Fibromyalgia
0.000 0.409 0.591
G25.2 Other specified forms of tremor
0.590 0.409 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.410 0.590
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.411 0.589
M70.3 Other bursitis of elbow
0.000 0.412 0.588
G44.8 Other specified headache syndromes
0.588 0.412 0.000
H40-H42 Glaucoma
0.000 0.413 0.587
E83.9 Disorder of mineral metabolism, unspecified
0.549 0.414 0.037
E83.8 Other disorders of mineral metabolism
0.549 0.414 0.037
E83.2 Disorders of zinc metabolism
0.549 0.414 0.037
E83.0 Disorders of copper metabolism
0.549 0.414 0.037
K77 Liver disorders in diseases classified elsewhere
0.000 0.416 0.584
K71 Toxic liver disease
0.000 0.416 0.584
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.416 0.584
M77.18 Lateral epicondylitis-Other
0.000 0.416 0.584
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.416 0.584
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.416 0.584
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.416 0.584
M77.14 Lateral epicondylitis-Hand
0.000 0.416 0.584
M77.13 Lateral epicondylitis-Forearm
0.000 0.416 0.584
M77.11 Lateral epicondylitis-Shldr region
0.000 0.416 0.584
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.416 0.584
M70.2 Olecranon bursitis
0.000 0.417 0.583
M86-M90 Other osteopathies
0.000 0.418 0.581
K74.4 Secondary biliary cirrhosis
0.000 0.418 0.582
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.418 0.582
K74.1 Hepatic sclerosis
0.000 0.418 0.582
K90.8 Other intestinal malabsorption
0.000 0.419 0.581
G04 Encephalitis, myelitis and encephalomyelitis
0.580 0.420 0.000
K51.2 Ulcerative (chronic) proctitis
0.577 0.423 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.576 0.424 0.000
M46.4 Discitis, unspecified
0.000 0.424 0.576
M70.49 Prepatellar bursitis-Site unspec
0.000 0.425 0.575
M70.48 Prepatellar bursitis-Other
0.000 0.425 0.575
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.425 0.575
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.425 0.575
M70.44 Prepatellar bursitis-Hand
0.000 0.425 0.575
M70.43 Prepatellar bursitis-Forearm
0.000 0.425 0.575
M70.42 Prepatellar bursitis-Upper arm
0.000 0.425 0.575
M70.41 Prepatellar bursitis-Shldr region
0.000 0.425 0.575
M70.40 Prepatellar bursitis-Mult sites
0.000 0.425 0.575
I36 Nonrheumatic tricuspid valve disorders
0.000 0.426 0.574
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.426 0.574
K51.8 Other ulcerative colitis
0.574 0.426 0.000
M76 Enthesopathies of lower limb, excluding foot
0.000 0.427 0.572
M07.38 Other psoriatic arthropathies (Other)
0.000 0.427 0.573
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.427 0.573
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.427 0.573
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.427 0.573
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.427 0.573
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.427 0.573
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.427 0.573
G30.9 Alzheimer's disease, unspecified
0.572 0.428 0.000
H35.0 Background retinopathy and retinal vascular changes
0.000 0.430 0.570
G25.3 Myoclonus
0.569 0.430 0.000
G24 Dystonia
0.569 0.431 0.000
G30.8 Other Alzheimer's disease
0.569 0.431 0.000
M77.4 Metatarsalgia
0.000 0.432 0.567
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.433 0.567
M79.6 Pain in limb
0.000 0.433 0.567
G41.0 Grand mal status epilepticus
0.566 0.434 0.000
K75 Other inflammatory liver diseases
0.000 0.434 0.566
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.436 0.564
M11.9 Crystal arthropathy, unspecified
0.000 0.436 0.564
M11.8 Other specified crystal arthropathies
0.000 0.436 0.564
M11.1 Familial chondrocalcinosis
0.000 0.436 0.564
M11.0 Hydroxyapatite deposition disease
0.000 0.436 0.564
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.001 0.436 0.563
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.438 0.562
I23.8 Other current complications following acute myocardial infarction
0.000 0.438 0.562
E73 Lactose intolerance
0.001 0.442 0.558
I31.3 Pericardial effusion (noninflammatory)
0.000 0.442 0.558
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.442 0.558
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.442 0.558
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.442 0.558
E74.2 Disorders of galactose metabolism
0.000 0.442 0.558
E74.1 Disorders of fructose metabolism
0.000 0.442 0.558

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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