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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28404158
log Bayes Factor = 15.9414
Chromosome 5   position 177,028,676  (GRCh37) Explore rs28404158 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
Chapter VIII Diseases of the ear and mastoid process
0.995 0.005 0.000
J40-J47 Chronic lower respiratory diseases
0.995 0.005 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.988 0.012 0.000
T81 Complications of procedures, not elsewhere classified
0.982 0.018 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.980 0.020 0.000
J09-J18 Influenza and pneumonia
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.979 0.021 0.000
J43 Emphysema
0.978 0.022 0.000
J44 Other chronic obstructive pulmonary disease
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.974 0.026 0.000
D70 Agranulocytosis
0.974 0.026 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.972 0.028 0.000
J43.9 Emphysema, unspecified
0.966 0.034 0.000
J18 Pneumonia, organism unspecified
0.959 0.041 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.958 0.042 0.000
H02 Other disorders of eyelid
0.955 0.045 0.000
M70-M79 Other soft tissue disorders
0.953 0.047 0.000
H25-H28 Disorders of lens
0.952 0.048 0.000
G90-G99 Other disorders of the nervous system
0.952 0.048 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.950 0.050 0.000
J95-J99 Other diseases of the respiratory system
0.947 0.053 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.941 0.059 0.000
H65-H75 Diseases of middle ear and mastoid
0.940 0.060 0.000
S00-S09 Injuries to the head
0.940 0.060 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.939 0.061 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.936 0.064 0.000
M45-M49 Spondylopathies
0.935 0.065 0.000
H90-H95 Other disorders of ear
0.932 0.068 0.000
J60-J70 Lung diseases due to external agents
0.932 0.068 0.000
J18.1 Lobar pneumonia, unspecified
0.931 0.069 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.931 0.069 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.931 0.069 0.000
D50-D53 Nutritional anaemias
0.930 0.070 0.000
H02.4 Ptosis of eyelid
0.929 0.071 0.000
M20-M25 Other joint disorders
0.927 0.073 0.000
H30-H36 Disorders of choroid and retina
0.924 0.076 0.000
O60-O75 Complications of labour and delivery
0.918 0.082 0.000
M79.8 Other specified soft tissue disorders
0.917 0.083 0.000
Chapter I Certain infectious and parasitic diseases
0.913 0.087 0.000
J90-J94 Other diseases of pleura
0.904 0.096 0.000
G91 Hydrocephalus
0.902 0.098 0.000
M80-M85 Disorders of bone density and structure
0.899 0.101 0.000
J30-J39 Other diseases of upper respiratory tract
0.898 0.102 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.898 0.102 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.896 0.104 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.892 0.108 0.000
H73 Other disorders of tympanic membrane
0.890 0.110 0.000
M05-M14 Inflammatory polyarthropathies
0.890 0.110 0.000
H35 Other retinal disorders
0.890 0.110 0.000
O47 False labour
0.885 0.115 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.885 0.115 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.884 0.116 0.000
H26 Other cataract
0.880 0.120 0.000
S01 Open wound of head
0.878 0.122 0.000
O48 Prolonged pregnancy
0.875 0.125 0.000
J69 Pneumonitis due to solids and liquids
0.872 0.128 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.869 0.131 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.866 0.134 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.864 0.136 0.000
D50 Iron deficiency anaemia
0.862 0.138 0.000
S90-S99 Injuries to the ankle and foot
0.858 0.142 0.000
H73.8 Other specified disorders of tympanic membrane
0.855 0.145 0.000
A30-A49 Other bacterial diseases
0.852 0.148 0.000
O63 Long labour
0.851 0.149 0.000
D60-D64 Aplastic and other anaemias
0.849 0.150 0.000
D73 Diseases of spleen
0.849 0.151 0.000
M47 Spondylosis
0.849 0.151 0.000
H80-H83 Diseases of inner ear
0.848 0.152 0.000
M20 Acquired deformities of fingers and toes
0.846 0.154 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.845 0.155 0.000
T82.1 Mechanical complication of cardiac electronic device
0.844 0.156 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.842 0.158 0.000
H04 Disorders of lachrymal system
0.842 0.158 0.000
H90 Conductive and sensorineural hearing loss
0.842 0.158 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.841 0.159 0.000
M79.6 Pain in limb
0.838 0.162 0.000
H60-H62 Diseases of external ear
0.837 0.163 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.835 0.165 0.000
M24 Other specific joint derangements
0.835 0.165 0.000
H02.1 Ectropion of eyelid
0.835 0.165 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.831 0.169 0.000
J69.0 Pneumonitis due to food and vomit
0.829 0.171 0.000
H25 Senile cataract
0.825 0.175 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.824 0.176 0.000
D80-D89 Certain disorders involving the immune mechanism
0.823 0.177 0.000
H35.0 Background retinopathy and retinal vascular changes
0.817 0.183 0.000
J47 Bronchiectasis
0.815 0.185 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.814 0.186 0.000
G91.9 Hydrocephalus, unspecified
0.813 0.187 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.809 0.191 0.000
J18.9 Pneumonia, unspecified
0.807 0.193 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.804 0.196 0.000
D50.9 Iron deficiency anaemia, unspecified
0.802 0.198 0.000
O63.1 Prolonged second stage (of labour)
0.802 0.198 0.000
H26.4 After-cataract
0.802 0.198 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.801 0.199 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.800 0.200 0.000
S40-S49 Injuries to the shoulder and upper arm
0.798 0.202 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.797 0.203 0.000
M91-M94 Chondropathies
0.796 0.204 0.000
M40-M43 Deforming dorsopathies
0.795 0.205 0.000
H92 Otalgia and effusion of ear
0.792 0.208 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.790 0.210 0.000
Y95 Nosocomial condition
0.790 0.210 0.000
M21 Other acquired deformities of limbs
0.789 0.211 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.789 0.211 0.000
J34 Other disorders of nose and nasal sinuses
0.789 0.211 0.000
J39 Other diseases of upper respiratory tract
0.788 0.212 0.000
H05 Disorders of orbit
0.788 0.212 0.000
A49 Bacterial infection of unspecified site
0.787 0.213 0.000
M79.67 Pain in limb (Ankle and foot)
0.786 0.214 0.000
T79-T79 Certain early complications of trauma
0.785 0.215 0.000
V80-V89 Other land transport accidents
0.784 0.216 0.000
J95.0 Tracheostomy malfunction
0.784 0.216 0.000
Chapter V Mental and behavioural disorders
0.783 0.217 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.781 0.219 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.778 0.222 0.000
M48 Other spondylopathies
0.776 0.224 0.000
J95.8 Other postprocedural respiratory disorders
0.776 0.224 0.000
H53-H54 Visual disturbances and blindness
0.775 0.225 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.775 0.225 0.000
T82.3 Mechanical complication of other vascular grafts
0.774 0.226 0.000
J90 Pleural effusion, not elsewhere classified
0.774 0.226 0.000
G95 Other diseases of spinal cord
0.773 0.226 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.769 0.231 0.000
M47.8 Other spondylosis
0.768 0.231 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.768 0.232 0.000
H55-H59 Other disorders of eye and adnexa
0.767 0.233 0.000
H43-H45 Disorders of vitreous body and globe
0.767 0.233 0.000
S80-S89 Injuries to the knee and lower leg
0.765 0.235 0.000
S00 Superficial injury of head
0.764 0.236 0.000
H35.4 Peripheral retinal degeneration
0.763 0.237 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.763 0.237 0.000
M65-M68 Disorders of synovium and tendon
0.763 0.237 0.000
M13 Other arthritis
0.763 0.237 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.763 0.237 0.000
M84 Disorders of continuity of bone
0.762 0.238 0.000
S01.8 Open wound of other parts of head
0.761 0.239 0.000
M79.1 Myalgia
0.761 0.239 0.000
T81.9 Unspecified complication of procedure
0.761 0.239 0.000
H74 Other disorders of middle ear and mastoid
0.760 0.240 0.000
G91.8 Other hydrocephalus
0.759 0.241 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.759 0.241 0.000
H01 Other inflammation of eyelid
0.754 0.245 0.000
J93 Pneumothorax
0.752 0.248 0.000
H04.1 Other disorders of lachrymal gland
0.750 0.250 0.000
S60-S69 Injuries to the wrist and hand
0.750 0.250 0.000
O44 Placenta praevia
0.749 0.251 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.747 0.253 0.000
S06 Intracranial injury
0.744 0.256 0.000
J14 Pneumonia due to Haemophilus influenzae
0.743 0.257 0.000
H25.9 Senile cataract, unspecified
0.741 0.259 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.741 0.259 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.741 0.259 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.741 0.259 0.000
O43 Placental disorders
0.741 0.259 0.000
O85-O92 Complications predominantly related to the puerperium
0.740 0.260 0.000
J38.0 Paralysis of vocal cords and larynx
0.740 0.260 0.000
M81 Osteoporosis without pathological fracture
0.740 0.260 0.000
W00-W19 Falls
0.739 0.261 0.000
D51 Vitamin B12 deficiency anaemia
0.739 0.261 0.000
S10-S19 Injuries to the neck
0.739 0.261 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.738 0.261 0.000
S01.1 Open wound of eyelid and periocular area
0.737 0.263 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.736 0.264 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.735 0.265 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.735 0.265 0.000
G96 Other disorders of central nervous system
0.735 0.265 0.000
O73 Retained placenta and membranes, without haemorrhage
0.734 0.266 0.000
H65 Nonsuppurative otitis media
0.734 0.266 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.733 0.267 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.731 0.269 0.000
G20-G26 Extrapyramidal and movement disorders
0.730 0.270 0.000
J94 Other pleural conditions
0.729 0.271 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.728 0.272 0.000
H26.8 Other specified cataract
0.727 0.273 0.000
H91 Other hearing loss
0.727 0.273 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.726 0.274 0.000
D75 Other diseases of blood and blood-forming organs
0.725 0.275 0.000
H35.6 Retinal haemorrhage
0.725 0.275 0.000
B35-B49 Mycoses
0.725 0.275 0.000
O80-O84 Delivery
0.723 0.277 0.000
M79.66 Pain in limb (Lower leg)
0.722 0.278 0.000
M25 Other joint disorders, not elsewhere classified
0.721 0.279 0.000
G91.1 Obstructive hydrocephalus
0.721 0.279 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.719 0.281 0.000
Y83.6 Removal of other organ (partial) (total)
0.719 0.281 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.719 0.281 0.000
B95-B98 Bacterial, viral and other infectious agents
0.719 0.281 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.719 0.281 0.000
O62 Abnormalities of forces of labour
0.719 0.281 0.000
M76 Enthesopathies of lower limb, excluding foot
0.718 0.282 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
D55-D59 Haemolytic anaemias
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.285 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.714 0.286 0.000
J91 Pleural effusion in conditions classified elsewhere
0.713 0.287 0.000
J41 Simple and mucopurulent chronic bronchitis
0.713 0.287 0.000
M20.4 Other hammer toe(s) (acquired)
0.713 0.287 0.000
J11 Influenza, virus not identified
0.712 0.288 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.712 0.288 0.000
D73.0 Hyposplenism
0.712 0.288 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.712 0.288 0.000
H02.3 Blepharochalasis
0.711 0.289 0.000
S91 Open wound of ankle and foot
0.710 0.290 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.710 0.290 0.000
M07 Psoriatic and enteropathic arthropathies
0.709 0.291 0.000
S70-S79 Injuries to the hip and thigh
0.709 0.291 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.709 0.291 0.000
D74 Methaemoglobinaemia
0.709 0.291 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.709 0.291 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.709 0.291 0.000
S20-S29 Injuries to the thorax
0.708 0.292 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.708 0.292 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.708 0.292 0.000
O66 Other obstructed labour
0.708 0.292 0.000
M46 Other inflammatory spondylopathies
0.708 0.292 0.000
J18.0 Bronchopneumonia, unspecified
0.707 0.293 0.000
D50.8 Other iron deficiency anaemias
0.707 0.293 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.707 0.293 0.000
J10 Influenza due to identified influenza virus
0.706 0.294 0.000
M34 Systemic sclerosis
0.705 0.295 0.000
M10 Gout
0.704 0.296 0.000
Chapter XXII Codes for special purposes
0.704 0.296 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.704 0.296 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.704 0.296 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.704 0.296 0.000
H10-H13 Disorders of conjunctiva
0.704 0.296 0.000
H90.3 Sensorineural hearing loss, bilateral
0.704 0.296 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.703 0.297 0.000
J17 Pneumonia in diseases classified elsewhere
0.703 0.297 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.703 0.297 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.703 0.297 0.000
J12 Viral pneumonia, not elsewhere classified
0.703 0.297 0.000
J09 Influenza due to certain identified influenza virus
0.703 0.297 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.702 0.298 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
Y00-Y09 Assault
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
X50-X57 Overexertion, travel and privation
0.702 0.298 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.298 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W75-W84 Other accidental threats to breathing
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
W50-W64 Exposure to animate mechanical forces
0.702 0.298 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V40-V49 Car occupant injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V20-V29 Motorcycle rider injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
J43.8 Other emphysema
0.701 0.299 0.000
J43.2 Centrilobular emphysema
0.701 0.299 0.000
J43.1 Panlobular emphysema
0.701 0.299 0.000
J43.0 MacLeod's syndrome
0.701 0.299 0.000
H35.9 Retinal disorder, unspecified
0.701 0.299 0.000
H80 Otosclerosis
0.700 0.300 0.000
J32 Chronic sinusitis
0.699 0.301 0.000
M86-M90 Other osteopathies
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.698 0.302 0.000
A49.8 Other bacterial infections of unspecified site
0.698 0.302 0.000
O45 Premature separation of placenta [abruptio placentae]
0.697 0.303 0.000
O41 Other disorders of amniotic fluid and membranes
0.697 0.303 0.000
O33 Maternal care for known or suspected disproportion
0.697 0.303 0.000
O31 Complications specific to multiple gestation
0.697 0.303 0.000
O40 Polyhydramnios
0.697 0.303 0.000
G93 Other disorders of brain
0.696 0.303 0.000
H25.8 Other senile cataract
0.696 0.304 0.000
H83 Other diseases of inner ear
0.696 0.304 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.695 0.304 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.694 0.305 0.000
S50-S59 Injuries to the elbow and forearm
0.694 0.306 0.000
V10-V19 Pedal cyclist injured in transport accident
0.694 0.306 0.000
D72 Other disorders of white blood cells
0.693 0.307 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.693 0.307 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.693 0.307 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.692 0.308 0.000
H36 Retinal disorders in diseases classified elsewhere
0.691 0.309 0.000
D86 Sarcoidosis
0.689 0.311 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.688 0.311 0.000
S99 Other and unspecified injuries of ankle and foot
0.688 0.312 0.000
J18.8 Other pneumonia, organism unspecified
0.688 0.312 0.000
J18.2 Hypostatic pneumonia, unspecified
0.688 0.312 0.000
G35 Multiple sclerosis
0.688 0.312 0.000
J00-J06 Acute upper respiratory infections
0.687 0.312 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.687 0.313 0.000
O97 Death from sequelae of direct obstetric causes
0.687 0.313 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.687 0.313 0.000
O95 Obstetric death of unspecified cause
0.687 0.313 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.687 0.313 0.000
Y43 Primarily systemic agents
0.686 0.313 0.000
H69 Other disorders of Eustachian tube
0.686 0.314 0.000
M20.2 Hallux rigidus
0.685 0.315 0.000
M82 Osteoporosis in diseases classified elsewhere
0.685 0.315 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.685 0.315 0.000
H02.5 Other disorders affecting eyelid function
0.685 0.315 0.000
H02.2 Lagophthalmos
0.685 0.315 0.000
M79.61 Pain in limb (Shoulder region)
0.685 0.315 0.000
G30-G32 Other degenerative diseases of the nervous system
0.685 0.315 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.684 0.316 0.000
O30 Multiple gestation
0.684 0.316 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.683 0.317 0.000
M71 Other bursopathies
0.683 0.317 0.000
J39.2 Other diseases of pharynx
0.683 0.317 0.000
M24.0 Loose body in joint
0.683 0.317 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.683 0.317 0.000
H27 Other disorders of lens
0.683 0.317 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.682 0.317 0.000
G90 Disorders of autonomic nervous system
0.682 0.317 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.682 0.317 0.000
G92 Toxic encephalopathy
0.682 0.317 0.000
M43 Other deforming dorsopathies
0.682 0.318 0.000
M85 Other disorders of bone density and structure
0.682 0.318 0.000
J37 Chronic laryngitis and laryngotracheitis
0.681 0.319 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.681 0.319 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.681 0.319 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.681 0.319 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.681 0.319 0.000
H90.5 Sensorineural hearing loss, unspecified
0.680 0.320 0.000
J96 Respiratory failure, not elsewhere classified
0.679 0.321 0.000
W20-W49 Exposure to inanimate mechanical forces
0.679 0.321 0.000
M11 Other crystal arthropathies
0.678 0.322 0.000
O61 Failed induction of labour
0.678 0.322 0.000
H92.0 Otalgia
0.678 0.322 0.000
O63.9 Long labour, unspecified
0.678 0.322 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.677 0.322 0.000
H61 Other disorders of external ear
0.677 0.323 0.000
S01.7 Multiple open wounds of head
0.677 0.323 0.000
S02 Fracture of skull and facial bones
0.676 0.323 0.000
H90.2 Conductive hearing loss, unspecified
0.676 0.324 0.000
Chapter XXI Factors influencing health status and contact with health services
0.676 0.324 0.000
S01.3 Open wound of ear
0.676 0.324 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.675 0.325 0.000
J38.3 Other diseases of vocal cords
0.674 0.325 0.000
M79.9 Soft tissue disorder, unspecified
0.674 0.326 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.674 0.326 0.000
M79.3 Panniculitis, unspecified
0.674 0.326 0.000
M79.2 Neuralgia and neuritis, unspecified
0.674 0.326 0.000
D73.5 Infarction of spleen
0.674 0.326 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.674 0.326 0.000
H70 Mastoiditis and related conditions
0.674 0.326 0.000
H68 Eustachian salpingitis and obstruction
0.674 0.326 0.000
H67 Otitis media in diseases classified elsewhere
0.674 0.326 0.000
S08 Traumatic amputation of part of head
0.674 0.326 0.000
S07 Crushing injury of head
0.674 0.326 0.000
S05 Injury of eye and orbit
0.674 0.326 0.000
S04 Injury of cranial nerves
0.674 0.326 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.674 0.326 0.000
M21.0 Valgus deformity, not elsewhere classified
0.672 0.328 0.000
D62 Acute posthaemorrhagic anaemia
0.671 0.329 0.000
M13.9 Arthritis, unspecified
0.671 0.329 0.000
M49 Spondylopathies in diseases classified elsewhere
0.671 0.329 0.000
H60 Otitis externa
0.670 0.330 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.668 0.332 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.668 0.332 0.000
A40 Streptococcal septicaemia
0.668 0.332 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.668 0.332 0.000
J70 Respiratory conditions due to other external agents
0.668 0.332 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.668 0.332 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.668 0.332 0.000
J66 Airway disease due to specific organic dust
0.668 0.332 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.668 0.332 0.000
J62 Pneumoconiosis due to dust containing silica
0.668 0.332 0.000
J65 Pneumoconiosis associated with tuberculosis
0.668 0.332 0.000
J64 Unspecified pneumoconiosis
0.668 0.332 0.000
J60 Coalworker's pneumoconiosis
0.668 0.332 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.667 0.332 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.667 0.332 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.667 0.332 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.667 0.332 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.667 0.332 0.000
H35.8 Other specified retinal disorders
0.667 0.332 0.000
D53 Other nutritional anaemias
0.667 0.333 0.000
D52 Folate deficiency anaemia
0.667 0.333 0.000
M20.1 Hallux valgus (acquired)
0.667 0.333 0.000
M77 Other enthesopathies
0.666 0.334 0.000
M45 Ankylosing spondylitis
0.665 0.335 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.664 0.335 0.000
M33 Dermatopolymyositis
0.664 0.335 0.000
M32 Systemic lupus erythematosus
0.664 0.335 0.000
M30 Polyarteritis nodosa and related conditions
0.664 0.335 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.664 0.336 0.000
Chapter IX Diseases of the circulatory system
0.664 0.336 0.000
S01.2 Open wound of nose
0.662 0.337 0.000
M48.0 Spinal stenosis
0.662 0.338 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.662 0.338 0.000
H31 Other disorders of choroid
0.662 0.338 0.000
H30 Chorioretinal inflammation
0.662 0.338 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.662 0.338 0.000
S90 Superficial injury of ankle and foot
0.661 0.339 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.661 0.339 0.000
H66 Suppurative and unspecified otitis media
0.661 0.339 0.000
M79.5 Residual foreign body in soft tissue
0.660 0.340 0.000
Y40 Systemic antibiotics
0.660 0.340 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.660 0.340 0.000
J86 Pyothorax
0.659 0.341 0.000
O74 Complications of anaesthesia during labour and delivery
0.658 0.342 0.000
O71 Other obstetric trauma
0.658 0.342 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.658 0.342 0.000
O60 Preterm delivery
0.658 0.342 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.658 0.342 0.000
M79.88 Other specified soft tissue disorders (Other)
0.658 0.342 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.658 0.342 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.658 0.342 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.658 0.342 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.658 0.342 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.658 0.342 0.000
S01.4 Open wound of cheek and temporomandibular area
0.657 0.343 0.000
H02.8 Other specified disorders of eyelid
0.657 0.343 0.000
M35 Other systemic involvement of connective tissue
0.657 0.343 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.655 0.344 0.000
M24.2 Disorder of ligament
0.655 0.345 0.000
X60-X84 Intentional self-harm
0.655 0.345 0.000
B99-B99 Other infectious diseases
0.654 0.346 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.654 0.346 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.654 0.346 0.000
B65-B83 Helminthiases
0.654 0.346 0.000
B50-B64 Protozoal diseases
0.654 0.346 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.654 0.346 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.654 0.346 0.000
A75-A79 Rickettsioses
0.654 0.346 0.000
A70-A74 Other diseases caused by chlamydiae
0.654 0.346 0.000
A65-A69 Other spirochaetal diseases
0.654 0.346 0.000
A20-A28 Certain zoonotic bacterial diseases
0.654 0.346 0.000
A15-A19 Tuberculosis
0.654 0.346 0.000
H46 Optic neuritis
0.652 0.348 0.000
J30 Vasomotor and allergic rhinitis
0.652 0.348 0.000
S01.9 Open wound of head, part unspecified
0.650 0.350 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.649 0.351 0.000
H02.0 Entropion and trichiasis of eyelid
0.649 0.351 0.000
M24.5 Contracture of joint
0.649 0.351 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.648 0.352 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.648 0.352 0.000
H02.6 Xanthelasma of eyelid
0.648 0.352 0.000
B25-B34 Other viral diseases
0.648 0.352 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.648 0.352 0.000
D61 Other aplastic anaemias
0.647 0.352 0.000
O36 Maternal care for other known or suspected foetal problems
0.647 0.353 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.647 0.353 0.000
G91.2 Normal-pressure hydrocephalus
0.647 0.353 0.000
G91.0 Communicating hydrocephalus
0.647 0.353 0.000
M79.0 Rheumatism, unspecified
0.647 0.353 0.000
A49.0 Staphylococcal infection, unspecified
0.646 0.354 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.645 0.355 0.000
A41 Other septicaemia
0.645 0.355 0.000
M83 Adult osteomalacia
0.645 0.355 0.000
A80-A89 Viral infections of the central nervous system
0.644 0.356 0.000
M47.9 Spondylosis, unspecified
0.644 0.356 0.000
Z60 Problems related to social environment
0.643 0.357 0.000
D64 Other anaemias
0.643 0.357 0.000
J38.2 Nodules of vocal cords
0.643 0.357 0.000
B15-B19 Viral hepatitis
0.641 0.359 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.641 0.359 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.640 0.360 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.640 0.360 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.639 0.361 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.638 0.361 0.000
H73.1 Chronic myringitis
0.638 0.361 0.000
H73.0 Acute myringitis
0.638 0.361 0.000
M14 Arthropathies in other diseases classified elsewhere
0.638 0.362 0.000
M12 Other specific arthropathies
0.638 0.362 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.638 0.362 0.000
M08 Juvenile arthritis
0.638 0.362 0.000
G83 Other paralytic syndromes
0.638 0.362 0.000
H35.7 Separation of retinal layers
0.638 0.362 0.000
H35.5 Hereditary retinal dystrophy
0.638 0.362 0.000
H35.2 Other proliferative retinopathy
0.638 0.362 0.000
H35.1 Retinopathy of prematurity
0.638 0.362 0.000
H57 Other disorders of eye and adnexa
0.637 0.363 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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