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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857151
log Bayes Factor = 32.4317
Chromosome 6   position 32,763,514  (GRCh37) Explore rs2857151 on Ensembl!
Variant rs2857151 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
L57.0 Actinic keratosis
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.999 0.001 0.000
C44.7 Skin of lower limb, including hip
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
C44.6 Skin of upper limb, including shoulder
0.999 0.001 0.000
L40.9 Psoriasis, unspecified
0.998 0.002 0.000
C44.3 Skin of other and unspecified parts of face
0.998 0.002 0.000
E05.9 Thyrotoxicosis, unspecified
0.996 0.004 0.000
L40-L45 Papulosquamous disorders
0.994 0.006 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.994 0.006 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.990 0.010 0.000
E23 Hypofunction and other disorders of pituitary gland
0.988 0.012 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.986 0.014 0.000
C44.4 Skin of scalp and neck
0.978 0.022 0.000
E27 Other disorders of adrenal gland
0.976 0.024 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.035 0.965
M07.3 Other psoriatic arthropathies
0.955 0.045 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.046 0.954
M07.39 Other psoriatic arthropathies (Site unspecified)
0.949 0.051 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.945 0.055 0.000
E10.9 Without complications
0.944 0.056 0.000
E23.7 Disorder of pituitary gland, unspecified
0.941 0.059 0.000
E27.1 Primary adrenocortical insufficiency
0.941 0.059 0.000
C44.2 Skin of ear and external auricular canal
0.941 0.059 0.000
E23.6 Other disorders of pituitary gland
0.938 0.062 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.936 0.064 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.068 0.932
J45.9 Asthma, unspecified
0.000 0.069 0.931
E10.2 With renal complications
0.918 0.082 0.000
E10.5 With peripheral circulatory complications
0.911 0.089 0.000
E24 Cushing's syndrome
0.908 0.092 0.000
Chapter II Neoplasms
0.901 0.099 0.000
E10.1 With ketoacidosis
0.899 0.101 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.894 0.106 0.000
# Top node
0.890 0.110 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.887 0.113 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.877 0.123 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.125 0.875
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.866 0.134 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.864 0.136 0.000
L43 Lichen planus
0.862 0.138 0.000
M07 Psoriatic and enteropathic arthropathies
0.859 0.141 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.856 0.144 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.849 0.151 0.000
Q60-Q64 Congenital malformations of the urinary system
0.847 0.153 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.846 0.154 0.000
E28 Ovarian dysfunction
0.846 0.154 0.000
E83.1 Disorders of iron metabolism
0.000 0.156 0.844
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.842 0.158 0.000
J45 Asthma
0.000 0.158 0.842
Q61 Cystic kidney disease
0.838 0.162 0.000
D43.0 Brain, supratentorial
0.834 0.166 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.833 0.167 0.000
L40.1 Generalised pustular psoriasis
0.830 0.170 0.000
L40.3 Pustulosis palmaris et plantaris
0.829 0.171 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.822 0.178 0.000
J45.0 Predominantly allergic asthma
0.000 0.182 0.818
E26 Hyperaldosteronism
0.815 0.185 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.812 0.188 0.000
Q50-Q56 Congenital malformations of genital organs
0.809 0.191 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.808 0.192 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.806 0.194 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.802 0.198 0.000
M05-M14 Inflammatory polyarthropathies
0.801 0.199 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.799 0.201 0.000
C44.0 Skin of lip
0.798 0.202 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.797 0.203 0.000
Q61.3 Polycystic kidney, unspecified
0.795 0.205 0.000
G36 Other acute disseminated demyelination
0.000 0.213 0.787
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.781 0.219 0.000
E10.0 With coma
0.780 0.220 0.000
Q80-Q89 Other congenital malformations
0.780 0.220 0.000
E06 Thyroiditis
0.778 0.222 0.000
E10.7 With multiple complications
0.777 0.223 0.000
E10.4 With neurological complications
0.777 0.223 0.000
M70-M79 Other soft tissue disorders
0.776 0.224 0.000
L44 Other papulosquamous disorders
0.775 0.225 0.000
C73 Malignant neoplasm of thyroid gland
0.773 0.227 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.771 0.229 0.000
L40.4 Guttate psoriasis
0.771 0.229 0.000
E23.0 Hypopituitarism
0.770 0.230 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.769 0.231 0.000
Q61.0 Congenital single renal cyst
0.769 0.231 0.000
E31 Polyglandular dysfunction
0.768 0.232 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.767 0.233 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.766 0.234 0.000
E13 Other specified diabetes mellitus
0.764 0.236 0.000
L57.5 Actinic granuloma
0.760 0.240 0.000
E11 Non-insulin-dependent diabetes mellitus
0.758 0.242 0.000
D47.2 Monoclonal gammopathy
0.757 0.243 0.000
L10-L14 Bullous disorders
0.754 0.246 0.000
E29 Testicular dysfunction
0.754 0.246 0.000
E24.0 Pituitary-dependent Cushing's disease
0.751 0.249 0.000
L40.0 Psoriasis vulgaris
0.749 0.251 0.000
C82.0 Small cleaved cell, follicular
0.747 0.253 0.000
D43.2 Brain, unspecified
0.745 0.255 0.000
E24.2 Drug-induced Cushing's syndrome
0.744 0.256 0.000
L43.9 Lichen planus, unspecified
0.743 0.257 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.736 0.264 0.000
Q53 Undescended testicle
0.735 0.265 0.000
C88 Malignant immunoproliferative diseases
0.730 0.270 0.000
E11.3 With ophthalmic complications
0.728 0.272 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.724 0.276 0.000
Q85 Phakomatoses, not elsewhere classified
0.723 0.277 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.723 0.277 0.000
E28.2 Polycystic ovarian syndrome
0.722 0.278 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.721 0.279 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.720 0.280 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.719 0.281 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.716 0.284 0.000
E00 Congenital iodine-deficiency syndrome
0.716 0.284 0.000
L41 Parapsoriasis
0.715 0.285 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.713 0.287 0.000
L57.3 Poikiloderma of Civatte
0.713 0.287 0.000
L57.2 Cutis rhomboidalis nuchae
0.713 0.287 0.000
L57.1 Actinic reticuloid
0.713 0.287 0.000
M71 Other bursopathies
0.711 0.289 0.000
E24.9 Cushing's syndrome, unspecified
0.710 0.290 0.000
L55 Sunburn
0.710 0.290 0.000
C91 Lymphoid leukaemia
0.709 0.291 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.708 0.291 0.000
E23.1 Drug-induced hypopituitarism
0.708 0.291 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.708 0.292 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.706 0.294 0.000
E34 Other endocrine disorders
0.705 0.295 0.000
C85.1 B-cell lymphoma, unspecified
0.703 0.297 0.000
E21.3 Hyperparathyroidism, unspecified
0.702 0.298 0.000
E27.5 Adrenomedullary hyperfunction
0.700 0.300 0.000
E27.0 Other adrenocortical overactivity
0.700 0.300 0.000
M79.1 Myalgia
0.697 0.303 0.000
E70-E90 Metabolic disorders
0.694 0.306 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.693 0.307 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.692 0.308 0.000
D40.0 Prostate
0.691 0.309 0.000
Q61.9 Cystic kidney disease, unspecified
0.690 0.309 0.000
E24.8 Other Cushing's syndrome
0.688 0.312 0.000
C12 Malignant neoplasm of pyriform sinus
0.688 0.312 0.000
M65-M68 Disorders of synovium and tendon
0.687 0.313 0.000
Q55 Other congenital malformations of male genital organs
0.685 0.315 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.685 0.315 0.000
E20 Hypoparathyroidism
0.685 0.315 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.684 0.315 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.684 0.315 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.684 0.316 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.316 0.684
G37.4 Subacute necrotising myelitis
0.000 0.316 0.684
G37.2 Central pontine myelinolysis
0.000 0.316 0.684
G37.1 Central demyelination of corpus callosum
0.000 0.316 0.684
G37.0 Diffuse sclerosis
0.000 0.316 0.684
C83.3 Large cell (diffuse)
0.684 0.316 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.683 0.317 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.681 0.319 0.000
M79.2 Neuralgia and neuritis, unspecified
0.679 0.321 0.000
D00-D09 In situ neoplasms
0.677 0.323 0.000
M79.18 Myalgia (Other)
0.675 0.325 0.000
E25 Adrenogenital disorders
0.673 0.326 0.000
E27.9 Disorder of adrenal gland, unspecified
0.672 0.328 0.000
E06.3 Autoimmune thyroiditis
0.671 0.329 0.000
Q53.1 Undescended testicle, unilateral
0.671 0.329 0.000
M70.4 Prepatellar bursitis
0.669 0.331 0.000
M76 Enthesopathies of lower limb, excluding foot
0.668 0.332 0.000
L43.8 Other lichen planus
0.668 0.332 0.000
C03 Malignant neoplasm of gum
0.668 0.332 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.667 0.333 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.666 0.334 0.000
D04 Carcinoma in situ of skin
0.665 0.335 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.665 0.335 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.664 0.336 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.663 0.336 0.000
E05.8 Other thyrotoxicosis
0.663 0.337 0.000
E26.9 Hyperaldosteronism, unspecified
0.662 0.338 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.661 0.339 0.000
M67 Other disorders of synovium and tendon
0.661 0.339 0.000
G36.0 Neuromyelitis optica [Devic]
0.000 0.340 0.660
E65-E68 Obesity and other hyperalimentation
0.659 0.341 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.658 0.342 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.657 0.343 0.000
E10.6 With other specified complications
0.657 0.343 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.654 0.346 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.654 0.346 0.000
C83.7 Burkitt's tumour
0.653 0.347 0.000
E27.2 Addisonian crisis
0.652 0.347 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.652 0.348 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.652 0.348 0.000
M07.38 Other psoriatic arthropathies (Other)
0.652 0.348 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.652 0.348 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.652 0.348 0.000
C82.4 Follicular lymphoma grade IIIb
0.651 0.349 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.651 0.349 0.000
E24.3 Ectopic ACTH syndrome
0.651 0.349 0.000
E24.1 Nelson's syndrome
0.651 0.349 0.000
L58 Radiodermatitis
0.651 0.349 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.651 0.349 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.648 0.352 0.000
J45.8 Mixed asthma
0.000 0.357 0.643
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.643 0.357 0.000
C91.9 Lymphoid leukaemia, unspecified
0.642 0.358 0.000
C02.9 Tongue, unspecified
0.642 0.358 0.000
D46 Myelodysplastic syndromes
0.641 0.359 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.641 0.359 0.000
D43.1 Brain, infratentorial
0.637 0.363 0.000
D45 Polycythaemia vera
0.637 0.363 0.000
C93 Monocytic leukaemia
0.636 0.363 0.000
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.636 0.364 0.000
Q61.5 Medullary cystic kidney
0.636 0.364 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.636 0.364 0.000
E23.2 Diabetes insipidus
0.635 0.365 0.000
Q52 Other congenital malformations of female genitalia
0.635 0.365 0.000
C82.2 Large cell, follicular
0.634 0.366 0.000
D48.5 Skin
0.634 0.366 0.000
E40-E46 Malnutrition
0.633 0.367 0.000
E28.3 Primary ovarian failure
0.631 0.369 0.000
C11 Malignant neoplasm of nasopharynx
0.631 0.369 0.000
Q64 Other congenital malformations of urinary system
0.629 0.371 0.000
J45.1 Nonallergic asthma
0.000 0.372 0.628
D43.4 Spinal cord
0.627 0.373 0.000
M08 Juvenile arthritis
0.627 0.373 0.000
E27.8 Other specified disorders of adrenal gland
0.626 0.374 0.000
M79.5 Residual foreign body in soft tissue
0.625 0.375 0.000
C94 Other leukaemias of specified cell type
0.622 0.378 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.622 0.378 0.000
Q51 Congenital malformations of uterus and cervix
0.622 0.378 0.000
E11.2 With renal complications
0.622 0.378 0.000
E89.0 Postprocedural hypothyroidism
0.622 0.378 0.000
D43.9 Central nervous system, unspecified
0.621 0.379 0.000
D43.7 Other parts of central nervous system
0.621 0.379 0.000
D43.3 Cranial nerves
0.621 0.379 0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.621 0.379 0.000
Q61.4 Renal dysplasia
0.619 0.381 0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg
0.619 0.381 0.000
M60-M63 Disorders of muscles
0.618 0.381 0.000
L43.3 Subacute (active) lichen planus
0.618 0.382 0.000
L43.2 Lichenoid drug reaction
0.618 0.382 0.000
L43.1 Bullous lichen planus
0.618 0.382 0.000
L43.0 Hypertrophic lichen planus
0.618 0.382 0.000
E78.2 Mixed hyperlipidaemia
0.618 0.382 0.000
L44.0 Pityriasis rubra pilaris
0.617 0.383 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.616 0.384 0.000
M07.5 Arthropathy in ulcerative colitis
0.616 0.384 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.616 0.384 0.000
M07.2 Psoriatic spondylitis
0.616 0.384 0.000
M07.1 Arthritis mutilans
0.616 0.384 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.616 0.384 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.616 0.384 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.615 0.385 0.000
C85.0 Lymphosarcoma
0.614 0.386 0.000
E26.0 Primary hyperaldosteronism
0.614 0.386 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.613 0.386 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.612 0.388 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.611 0.389 0.000
Q85.9 Phakomatosis, unspecified
0.611 0.389 0.000
Chapter I Certain infectious and parasitic diseases
0.611 0.389 0.000
E78.5 Hyperlipidaemia, unspecified
0.611 0.389 0.000
D47.1 Chronic myeloproliferative disease
0.610 0.390 0.000
M80-M85 Disorders of bone density and structure
0.610 0.390 0.000
E21.4 Other specified disorders of parathyroid gland
0.608 0.392 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.607 0.393 0.000
E28.9 Ovarian dysfunction, unspecified
0.606 0.394 0.000
E28.8 Other ovarian dysfunction
0.606 0.394 0.000
E28.1 Androgen excess
0.606 0.394 0.000
E28.0 Oestrogen excess
0.606 0.394 0.000
E11.7 With multiple complications
0.605 0.395 0.000
D04.5 Skin of trunk
0.604 0.396 0.000
L42 Pityriasis rosea
0.603 0.397 0.000
C86 Other specified types of T/NK-cell lymphoma
0.603 0.397 0.000
C95 Leukaemia of unspecified cell type
0.602 0.398 0.000
E11.0 With coma
0.602 0.398 0.000
E31.0 Autoimmune polyglandular failure
0.602 0.398 0.000
Q61.8 Other cystic kidney diseases
0.601 0.399 0.000
Q61.1 Polycystic kidney, infantile type
0.601 0.399 0.000
C83.1 Small cleaved cell (diffuse)
0.598 0.402 0.000
C82.6 Cutaneous follicle centre lymphoma
0.597 0.403 0.000
C82.5 Diffuse follicle centre lymphoma
0.597 0.403 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.404 0.596
D04.3 Skin of other and unspecified parts of face
0.594 0.406 0.000
C84.5 Other and unspecified T-cell lymphomas
0.593 0.407 0.000
C43 Malignant melanoma of skin
0.593 0.407 0.000
L10 Pemphigus
0.592 0.408 0.000
B15-B19 Viral hepatitis
0.590 0.410 0.000
M67.8 Other specified disorders of synovium and tendon
0.589 0.411 0.000
M79.9 Soft tissue disorder, unspecified
0.588 0.412 0.000
E04 Other non-toxic goitre
0.588 0.412 0.000
C07 Malignant neoplasm of parotid gland
0.588 0.412 0.000
E78.6 Lipoprotein deficiency
0.586 0.414 0.000
M10 Gout
0.585 0.415 0.000
Q00-Q07 Congenital malformations of the nervous system
0.585 0.415 0.000
C83.2 Mixed small and large cell (diffuse)
0.585 0.415 0.000
E10.8 With unspecified complications
0.584 0.416 0.000
E26.8 Other hyperaldosteronism
0.584 0.416 0.000
E26.1 Secondary hyperaldosteronism
0.584 0.416 0.000
M67.1 Other contracture of tendon (sheath)
0.583 0.417 0.000
Q43 Other congenital malformations of intestine
0.583 0.417 0.000
E13.9 Without complications
0.582 0.418 0.000
C02.8 Overlapping lesion of tongue
0.581 0.419 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.580 0.420 0.000
Q89 Other congenital malformations, not elsewhere classified
0.580 0.420 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.580 0.420 0.000
C00 Malignant neoplasm of lip
0.579 0.421 0.000
E29.1 Testicular hypofunction
0.577 0.423 0.000
E06.5 Other chronic thyroiditis
0.577 0.423 0.000
E34.8 Other specified endocrine disorders
0.577 0.423 0.000
C02.2 Ventral surface of tongue
0.576 0.424 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.576 0.424 0.000
E21.2 Other hyperparathyroidism
0.575 0.425 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.575 0.425 0.000
L60-L75 Disorders of skin appendages
0.574 0.426 0.000
D40.1 Testis
0.574 0.426 0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.574 0.426 0.000
C05 Malignant neoplasm of palate
0.573 0.427 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.573 0.427 0.000
Q53.2 Undescended testicle, bilateral
0.572 0.427 0.000
C74 Malignant neoplasm of adrenal gland
0.572 0.428 0.000
D47.4 Osteomyelofibrosis
0.571 0.429 0.000
E88 Other metabolic disorders
0.571 0.429 0.000
M07.6 Other enteropathic arthropathies
0.570 0.429 0.000
M79.7 Fibromyalgia
0.568 0.432 0.000
C90.2 Plasmacytoma, extramedullary
0.568 0.432 0.000
M79.11 Myalgia (Shoulder region)
0.568 0.432 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.566 0.434 0.000
E65 Localised adiposity
0.565 0.435 0.000
B18 Chronic viral hepatitis
0.565 0.435 0.000
G36.9 Acute disseminated demyelination, unspecified
0.000 0.435 0.564
G36.8 Other specified acute disseminated demyelination
0.000 0.435 0.564
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.435 0.564
C04 Malignant neoplasm of floor of mouth
0.564 0.436 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.563 0.437 0.000
M77 Other enthesopathies
0.563 0.437 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.563 0.437 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.563 0.437 0.000
E13.3 With ophthalmic complications
0.562 0.438 0.000
M76.6 Achilles tendinitis
0.562 0.438 0.000
L12 Pemphigoid
0.562 0.438 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.562 0.438 0.000
L59.0 Erythema ab igne [dermatitis ab igne]
0.560 0.440 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.559 0.441 0.000
Q84 Other congenital malformations of integument
0.559 0.441 0.000
Q81 Epidermolysis bullosa
0.559 0.441 0.000
Q80 Congenital ichthyosis
0.559 0.441 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.559 0.441 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.558 0.442 0.000
E06.4 Drug-induced thyroiditis
0.558 0.442 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.558 0.442 0.000
E06.0 Acute thyroiditis
0.558 0.442 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.557 0.443 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.557 0.443 0.000
E06.9 Thyroiditis, unspecified
0.556 0.444 0.000
Q61.2 Polycystic kidney, adult type
0.556 0.444 0.000
Q83 Congenital malformations of breast
0.556 0.444 0.000
L44.9 Papulosquamous disorder, unspecified
0.555 0.444 0.000
L44.8 Other specified papulosquamous disorders
0.555 0.444 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.555 0.444 0.000
L44.3 Lichen ruber moniliformis
0.555 0.444 0.000
L44.2 Lichen striatus
0.555 0.444 0.000
L44.1 Lichen nitidus
0.555 0.444 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.555 0.445 0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.553 0.447 0.000
C83.6 Undifferentiated (diffuse)
0.553 0.447 0.000
C83.4 Immunoblastic (diffuse)
0.553 0.447 0.000
Q35-Q37 Cleft lip and cleft palate
0.553 0.447 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.552 0.447 0.000
E31.9 Polyglandular dysfunction, unspecified
0.550 0.449 0.000
E31.8 Other polyglandular dysfunction
0.550 0.449 0.000
E31.1 Polyglandular hyperfunction
0.550 0.449 0.000
D40.9 Male genital organ, unspecified
0.550 0.450 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.550 0.450 0.000
L56.3 Solar urticaria
0.549 0.451 0.000
L56.2 Photocontact dermatitis [berloque dermatitis]
0.549 0.451 0.000
L56.1 Drug photoallergic response
0.549 0.451 0.000
L56.0 Drug phototoxic response
0.549 0.451 0.000
M82 Osteoporosis in diseases classified elsewhere
0.549 0.451 0.000
Q63 Other congenital malformations of kidney
0.548 0.452 0.000
C09 Malignant neoplasm of tonsil
0.548 0.452 0.000
E13.8 With unspecified complications
0.548 0.452 0.000
E13.7 With multiple complications
0.548 0.452 0.000
E13.6 With other specified complications
0.548 0.452 0.000
E13.5 With peripheral circulatory complications
0.548 0.452 0.000
E13.4 With neurological complications
0.548 0.452 0.000
E13.2 With renal complications
0.548 0.452 0.000
E13.1 With ketoacidosis
0.548 0.452 0.000
E13.0 With coma
0.548 0.452 0.000
E78.1 Pure hyperglyceridaemia
0.548 0.452 0.000
E16 Other disorders of pancreatic internal secretion
0.547 0.453 0.000
C81 Hodgkin's disease
0.546 0.454 0.000
D04.2 Skin of ear and external auricular canal
0.544 0.456 0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate
0.544 0.456 0.000
C91.0 Acute lymphoblastic leukaemia
0.543 0.457 0.000
C13 Malignant neoplasm of hypopharynx
0.542 0.458 0.000
M71.9 Bursopathy, unspecified
0.542 0.458 0.000
L14 Bullous disorders in diseases classified elsewhere
0.541 0.459 0.000
M76.0 Gluteal tendinitis
0.541 0.459 0.000
E29.9 Testicular dysfunction, unspecified
0.540 0.460 0.000
E29.8 Other testicular dysfunction
0.540 0.460 0.000
E29.0 Testicular hyperfunction
0.540 0.460 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.540 0.460 0.000
E79 Disorders of purine and pyrimidine metabolism
0.539 0.460 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.539 0.461 0.000
D06 Carcinoma in situ of cervix uteri
0.538 0.462 0.000
E34.3 Short stature, not elsewhere classified
0.537 0.463 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.537 0.463 0.000
C91.5 Adult T-cell leukaemia
0.536 0.464 0.000
C03.0 Upper gum
0.536 0.464 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.535 0.465 0.000
L11 Other acantholytic disorders
0.535 0.465 0.000
Q51.2 Other doubling of uterus
0.534 0.466 0.000
Q55.0 Absence and aplasia of testis
0.532 0.468 0.000
M71.3 Other bursal cyst
0.532 0.468 0.000
C03.1 Lower gum
0.532 0.468 0.000
M79.10 Myalgia (Multiple sites)
0.532 0.468 0.000
C83.5 Lymphoblastic (diffuse)
0.531 0.469 0.000
E22 Hyperfunction of pituitary gland
0.531 0.469 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.531 0.469 0.000
Q45 Other congenital malformations of digestive system
0.529 0.470 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.529 0.471 0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)
0.528 0.472 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.528 0.472 0.000
M76.7 Peroneal tendinitis
0.528 0.472 0.000
E15 Nondiabetic hypoglycaemic coma
0.528 0.472 0.000
C90.3 Solitary plasmacytoma
0.527 0.473 0.000
Q53.0 Ectopic testis
0.527 0.473 0.000
E04.0 Non-toxic diffuse goitre
0.527 0.473 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.526 0.473 0.000
M67.0 Short Achilles tendon (acquired)
0.526 0.474 0.000
M96.5 Postradiation scoliosis
0.526 0.474 0.000
M71.8 Other specified bursopathies
0.525 0.474 0.000
E11.6 With other specified complications
0.525 0.475 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.524 0.476 0.000
C88.7 Other malignant immunoproliferative diseases
0.524 0.476 0.000
C88.3 Immunoproliferative small intestinal disease
0.524 0.476 0.000
C88.2 Gamma heavy chain disease
0.524 0.476 0.000
C88.1 Alpha heavy chain disease
0.524 0.476 0.000
L40.8 Other psoriasis
0.523 0.477 0.000
E11.8 With unspecified complications
0.523 0.477 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.521 0.479 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.521 0.479 0.000
L13 Other bullous disorders
0.520 0.479 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.519 0.480 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.519 0.480 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.519 0.481 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.519 0.481 0.000
M79.56 Residual foreign body in soft tissue (Lower leg)
0.519 0.481 0.000
Q55.6 Other congenital malformations of penis
0.518 0.482 0.000
C02.0 Dorsal surface of tongue
0.517 0.483 0.000
D04.4 Skin of scalp and neck
0.517 0.483 0.000
B16 Acute hepatitis B
0.517 0.483 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.517 0.483 0.000
M79.3 Panniculitis, unspecified
0.515 0.484 0.000
E70 Disorders of aromatic amino-acid metabolism
0.515 0.485 0.000
L41.1 Pityriasis lichenoides chronica
0.514 0.485 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.514 0.486 0.000
E30.8 Other disorders of puberty
0.514 0.486 0.000
E30.1 Precocious puberty
0.514 0.486 0.000
E30.0 Delayed puberty
0.514 0.486 0.000
E32.9 Disease of thymus, unspecified
0.514 0.486 0.000
E32.8 Other diseases of thymus
0.514 0.486 0.000
E32.1 Abscess of thymus
0.514 0.486 0.000
E32.0 Persistent hyperplasia of thymus
0.514 0.486 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.514 0.486 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.514 0.486 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
L57.4 Cutis laxa senilis
0.513 0.486 0.000
Q39 Congenital malformations of oesophagus
0.513 0.487 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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