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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857600
log Bayes Factor = 118.19
Chromosome 6   position 31,582,287  (GRCh37) Explore rs2857600 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
E11.9 Without complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.001 0.999
H36.0 Diabetic retinopathy
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
I20.9 Angina pectoris, unspecified
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.003 0.997
E83.1 Disorders of iron metabolism
0.997 0.003 0.000
I25.1 Atherosclerotic heart disease
0.000 0.004 0.996
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.004 0.996
G37.9 Demyelinating disease of central nervous system, unspecified
0.995 0.005 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.006 0.994
E14.9 Without complications
0.000 0.006 0.994
G20-G26 Extrapyramidal and movement disorders
0.993 0.007 0.000
E10.4 With neurological complications
0.000 0.007 0.993
E70-E90 Metabolic disorders
0.000 0.008 0.992
H43-H45 Disorders of vitreous body and globe
0.000 0.008 0.992
G20 Parkinson's disease
0.991 0.009 0.000
I22 Subsequent myocardial infarction
0.000 0.009 0.991
H43 Disorders of vitreous body
0.000 0.010 0.990
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.011 0.989
L43 Lichen planus
0.000 0.011 0.989
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.012 0.988
I20.0 Unstable angina
0.000 0.014 0.986
H43.8 Other disorders of vitreous body
0.000 0.017 0.983
E16 Other disorders of pancreatic internal secretion
0.000 0.018 0.982
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.019 0.981
L43.9 Lichen planus, unspecified
0.000 0.020 0.980
E14.3 With ophthalmic complications
0.000 0.021 0.979
M70-M79 Other soft tissue disorders
0.000 0.021 0.979
J45.9 Asthma, unspecified
0.000 0.024 0.976
M45-M49 Spondylopathies
0.000 0.024 0.976
E16.2 Hypoglycaemia, unspecified
0.000 0.024 0.976
M45 Ankylosing spondylitis
0.000 0.025 0.975
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.029 0.971
I25.5 Ischaemic cardiomyopathy
0.000 0.030 0.970
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.040 0.960
I24 Other acute ischaemic heart diseases
0.000 0.041 0.959
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.053 0.947
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.059 0.941
E07 Other disorders of thyroid
0.000 0.059 0.941
H43.3 Other vitreous opacities
0.000 0.061 0.939
M75 Shoulder lesions
0.000 0.061 0.939
I30-I52 Other forms of heart disease
0.000 0.063 0.937
I25.2 Old myocardial infarction
0.000 0.063 0.937
I47 Paroxysmal tachycardia
0.000 0.065 0.935
M75.0 Adhesive capsulitis of shoulder
0.000 0.077 0.923
H34 Retinal vascular occlusions
0.000 0.079 0.921
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.081 0.919
I47.1 Supraventricular tachycardia
0.000 0.084 0.916
H35 Other retinal disorders
0.000 0.084 0.916
M05 Seropositive rheumatoid arthritis
0.000 0.090 0.910
I12 Hypertensive renal disease
0.000 0.092 0.908
I15 Secondary hypertension
0.000 0.102 0.898
G30-G32 Other degenerative diseases of the nervous system
0.895 0.105 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.105 0.895
E78.2 Mixed hyperlipidaemia
0.000 0.106 0.894
M07 Psoriatic and enteropathic arthropathies
0.000 0.109 0.891
G37.8 Other specified demyelinating diseases of central nervous system
0.890 0.109 0.000
E10.5 With peripheral circulatory complications
0.000 0.111 0.889
E13 Other specified diabetes mellitus
0.000 0.111 0.889
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.115 0.885
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.116 0.884
I51 Complications and ill-defined descriptions of heart disease
0.000 0.117 0.883
H35.8 Other specified retinal disorders
0.000 0.119 0.881
I35 Nonrheumatic aortic valve disorders
0.000 0.119 0.881
G40-G47 Episodic and paroxysmal disorders
0.880 0.120 0.000
M77 Other enthesopathies
0.000 0.120 0.880
I35.0 Aortic (valve) stenosis
0.000 0.124 0.876
I51.8 Other ill-defined heart diseases
0.000 0.129 0.871
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.131 0.869
I20.1 Angina pectoris with documented spasm
0.000 0.135 0.865
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.138 0.862
I12.9 Hypertensive renal disease without renal failure
0.000 0.140 0.860
E11.1 With ketoacidosis
0.000 0.143 0.857
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.144 0.856
E78.8 Other disorders of lipoprotein metabolism
0.000 0.144 0.856
E11.3 With ophthalmic complications
0.000 0.149 0.851
I47.2 Ventricular tachycardia
0.000 0.154 0.846
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.154 0.846
E10.2 With renal complications
0.000 0.159 0.841
H34.8 Other retinal vascular occlusions
0.000 0.160 0.840
E11.2 With renal complications
0.000 0.162 0.838
M77.1 Lateral epicondylitis
0.000 0.170 0.830
G25 Other extrapyramidal and movement disorders
0.830 0.170 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.172 0.828
M06.3 Rheumatoid nodule
0.000 0.173 0.827
I15.1 Hypertension secondary to other renal disorders
0.000 0.175 0.825
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.177 0.823
M65-M68 Disorders of synovium and tendon
0.000 0.179 0.821
I25.3 Aneurysm of heart
0.000 0.184 0.816
G00-G09 Inflammatory diseases of the central nervous system
0.815 0.185 0.000
M07.3 Other psoriatic arthropathies
0.000 0.187 0.813
E83 Disorders of mineral metabolism
0.756 0.187 0.057
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.188 0.812
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.188 0.812
E13.9 Without complications
0.000 0.191 0.809
E11.0 With coma
0.000 0.192 0.808
E10.6 With other specified complications
0.000 0.194 0.806
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.199 0.801
M70.4 Prepatellar bursitis
0.000 0.199 0.801
M75.2 Bicipital tendinitis
0.000 0.201 0.799
E05.9 Thyrotoxicosis, unspecified
0.000 0.201 0.799
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.205 0.795
L43.8 Other lichen planus
0.000 0.210 0.790
K90 Intestinal malabsorption
0.000 0.215 0.785
L40.8 Other psoriasis
0.000 0.217 0.783
H43.9 Disorder of vitreous body, unspecified
0.000 0.217 0.783
G46 Vascular syndromes of brain in cerebrovascular diseases
0.783 0.217 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.780 0.220 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.222 0.778
E74 Other disorders of carbohydrate metabolism
0.000 0.224 0.775
M75.4 Impingement syndrome of shoulder
0.000 0.227 0.773
G30 Alzheimer's disease
0.767 0.233 0.000
M75.3 Calcific tendinitis of shoulder
0.000 0.234 0.766
M11 Other crystal arthropathies
0.000 0.235 0.765
I46 Cardiac arrest
0.000 0.237 0.763
G40 Epilepsy
0.762 0.238 0.000
I47.0 Reentry ventricular arrhythmia
0.000 0.241 0.759
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.242 0.758
E78.4 Other hyperlipidaemia
0.000 0.244 0.756
M65 Synovitis and tenosynovitis
0.000 0.252 0.748
I11 Hypertensive heart disease
0.000 0.252 0.748
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.744 0.256 0.000
E03.8 Other specified hypothyroidism
0.000 0.256 0.743
I23 Certain current complications following acute myocardial infarction
0.000 0.257 0.743
H35.6 Retinal haemorrhage
0.000 0.257 0.743
E11.5 With peripheral circulatory complications
0.000 0.258 0.742
E78.1 Pure hyperglyceridaemia
0.000 0.259 0.741
H35.4 Peripheral retinal degeneration
0.000 0.261 0.739
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.262 0.738
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.736 0.263 0.000
E40-E46 Malnutrition
0.000 0.264 0.736
E14.4 With neurological complications
0.000 0.267 0.733
G41 Status epilepticus
0.733 0.267 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.267 0.733
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.267 0.733
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.269 0.731
E06 Thyroiditis
0.000 0.269 0.731
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.271 0.729
H34.2 Other retinal artery occlusions
0.000 0.272 0.728
H35.2 Other proliferative retinopathy
0.000 0.272 0.728
K90-K93 Other diseases of the digestive system
0.000 0.276 0.724
H35.5 Hereditary retinal dystrophy
0.000 0.278 0.722
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.282 0.718
Chapter XI Diseases of the digestive system
0.000 0.282 0.718
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.716
E14.7 With multiple complications
0.000 0.283 0.716
E14.5 With peripheral circulatory complications
0.000 0.283 0.716
E14.2 Withrenal complications
0.000 0.283 0.716
E14.1 With ketoacidosis
0.000 0.283 0.716
E14.0 With coma
0.000 0.283 0.716
M46 Other inflammatory spondylopathies
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H30 Chorioretinal inflammation
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.285 0.715
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.285 0.715
E78.6 Lipoprotein deficiency
0.000 0.285 0.715
E78.3 Hyperchylomicronaemia
0.000 0.285 0.715
G23 Other degenerative diseases of basal ganglia
0.712 0.288 0.000
G21 Secondary Parkinsonism
0.712 0.288 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.712 0.288 0.000
G22 Parkinsonism in diseases classified elsewhere
0.712 0.288 0.000
L42 Pityriasis rosea
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.711
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.711
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.711
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.711
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.711
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.711
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.289 0.711
K70-K77 Diseases of liver
0.000 0.289 0.711
H43.2 Crystalline deposits in vitreous body
0.000 0.290 0.710
H43.0 Vitreous prolapse
0.000 0.290 0.710
G47 Sleep disorders
0.710 0.290 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.291 0.709
L43.3 Subacute (active) lichen planus
0.000 0.291 0.709
L43.2 Lichenoid drug reaction
0.000 0.291 0.709
L43.1 Bullous lichen planus
0.000 0.291 0.709
L43.0 Hypertrophic lichen planus
0.000 0.291 0.709
K74 Fibrosis and cirrhosis of liver
0.000 0.292 0.708
I21 Acute myocardial infarction
0.000 0.295 0.705
M06.4 Inflammatory polyarthropathy
0.000 0.295 0.705
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.296 0.704
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.296 0.704
E16.4 Abnormal secretion of gastrin
0.000 0.296 0.704
E16.3 Increased secretion of glucagon
0.000 0.296 0.704
E16.1 Other hypoglycaemia
0.000 0.296 0.704
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.298 0.702
M91-M94 Chondropathies
0.000 0.299 0.701
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.300 0.700
K74.3 Primary biliary cirrhosis
0.000 0.300 0.700
E83.3 Disorders of phosphorus metabolism
0.683 0.300 0.017
G44 Other headache syndromes
0.700 0.300 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.300 0.700
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.301 0.699
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.301 0.699
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.301 0.699
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.301 0.699
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.301 0.699
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.301 0.699
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.301 0.699
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.301 0.699
M49 Spondylopathies in diseases classified elsewhere
0.000 0.301 0.699
G31.9 Degenerative disease of nervous system, unspecified
0.699 0.301 0.000
L40.0 Psoriasis vulgaris
0.000 0.302 0.697
H34.1 Central retinal artery occlusion
0.000 0.303 0.697
E79 Disorders of purine and pyrimidine metabolism
0.000 0.304 0.695
I51.0 Cardiac septal defect, acquired
0.000 0.305 0.695
E07.8 Other specified disorders of thyroid
0.000 0.306 0.694
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.306 0.694
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.308 0.692
I51.9 Heart disease, unspecified
0.000 0.308 0.692
M14 Arthropathies in other diseases classified elsewhere
0.000 0.310 0.689
M06.34 Rheumatoid nodule (Hand)
0.000 0.311 0.689
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.316 0.684
M71 Other bursopathies
0.000 0.317 0.682
M77.5 Other enthesopathy of foot
0.000 0.318 0.682
G46.7 Other lacunar syndromes
0.680 0.320 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.321 0.679
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.321 0.678
I51.6 Cardiovascular disease, unspecified
0.000 0.322 0.678
E07.1 Dyshormogenetic goitre
0.000 0.326 0.674
E07.0 Hypersecretion of calcitonin
0.000 0.326 0.674
M75.8 Other shoulder lesions
0.000 0.326 0.673
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.327 0.673
I31 Other diseases of pericardium
0.000 0.327 0.673
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.672 0.328 0.000
I52 Other heart disorders in diseases classified elsewhere
0.000 0.328 0.672
I48 Atrial fibrillation and flutter
0.000 0.328 0.672
I41 Myocarditis in diseases classified elsewhere
0.000 0.328 0.672
I40 Acute myocarditis
0.000 0.328 0.672
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.328 0.672
I32 Pericarditis in diseases classified elsewhere
0.000 0.328 0.672
E11.8 With unspecified complications
0.000 0.329 0.671
G09 Sequelae of inflammatory diseases of central nervous system
0.669 0.331 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.669 0.331 0.000
I25.4 Coronary artery aneurysm
0.000 0.333 0.667
M79.6 Pain in limb
0.000 0.337 0.663
H34.0 Transient retinal artery occlusion
0.000 0.339 0.660
M12 Other specific arthropathies
0.000 0.340 0.659
G00 Bacterial meningitis, not elsewhere classified
0.659 0.341 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.658 0.342 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.658 0.342 0.000
G90-G99 Other disorders of the nervous system
0.657 0.343 0.000
H31 Other disorders of choroid
0.000 0.343 0.657
H35.1 Retinopathy of prematurity
0.000 0.343 0.657
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.344 0.656
K72 Hepatic failure, not elsewhere classified
0.000 0.344 0.656
G40.9 Epilepsy, unspecified
0.655 0.345 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.347 0.653
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.347 0.653
M05.8 Other seropositive rheumatoid arthritis
0.000 0.347 0.652
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.347 0.652
M05.2 Rheumatoid vasculitis
0.000 0.347 0.652
M05.1 Rheumatoid lung disease
0.000 0.347 0.652
M05.0 Felty's syndrome
0.000 0.347 0.652
I46.9 Cardiac arrest, unspecified
0.000 0.348 0.652
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.349 0.651
G83 Other paralytic syndromes
0.650 0.350 0.000
M79.7 Fibromyalgia
0.000 0.350 0.650
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.351 0.649
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.351 0.649
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.354 0.646
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.355 0.645
I15.9 Seconday hypertension, unspecified
0.000 0.356 0.644
I15.8 Other secondary hypertension
0.000 0.356 0.644
I15.2 Hypertension secondary to endocrine disorders
0.000 0.356 0.644
I15.0 Renovascular hypertension
0.000 0.356 0.644
I44 Atrioventricular and left bundle-branch block
0.000 0.356 0.644
G30.9 Alzheimer's disease, unspecified
0.643 0.357 0.000
E84 Cystic fibrosis
0.001 0.357 0.642
H34.9 Retinal vascular occlusion, unspecified
0.000 0.357 0.642
M07.6 Other enteropathic arthropathies
0.000 0.361 0.639
M07.5 Arthropathy in ulcerative colitis
0.000 0.361 0.639
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.361 0.639
M07.2 Psoriatic spondylitis
0.000 0.361 0.639
M07.1 Arthritis mutilans
0.000 0.361 0.639
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.361 0.639
G25.9 Extrapyramidal and movement disorder, unspecified
0.639 0.361 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.362 0.638
E14.6 With other specified complications
0.000 0.362 0.637
E13.8 With unspecified complications
0.000 0.363 0.637
E13.7 With multiple complications
0.000 0.363 0.637
E13.6 With other specified complications
0.000 0.363 0.637
E13.5 With peripheral circulatory complications
0.000 0.363 0.637
E13.4 With neurological complications
0.000 0.363 0.637
E13.3 With ophthalmic complications
0.000 0.363 0.637
E13.2 With renal complications
0.000 0.363 0.637
E13.1 With ketoacidosis
0.000 0.363 0.637
E13.0 With coma
0.000 0.363 0.637
M77.0 Medial epicondylitis
0.000 0.364 0.636
G46.4 Cerebellar stroke syndrome
0.634 0.366 0.000
E05.5 Thyroid crisis or storm
0.000 0.366 0.634
E05.4 Thyrotoxicosis factitia
0.000 0.366 0.634
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.366 0.634
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.366 0.634
I51.5 Myocardial degeneration
0.000 0.367 0.633
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.367 0.633
G25.2 Other specified forms of tremor
0.633 0.367 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.369 0.631
M77.3 Calcaneal spur
0.000 0.369 0.631
M77.2 Periarthritis of wrist
0.000 0.369 0.631
M70.7 Other bursitis of hip
0.000 0.372 0.628
H40-H42 Glaucoma
0.000 0.373 0.627
I35.8 Other aortic valve disorders
0.000 0.375 0.625
M70.5 Other bursitis of knee
0.000 0.375 0.625
H35.7 Separation of retinal layers
0.000 0.376 0.624
L10-L14 Bullous disorders
0.000 0.376 0.623
G30.8 Other Alzheimer's disease
0.623 0.377 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.378 0.621
H43.1 Vitreous haemorrhage
0.000 0.379 0.621
I22.8 Subsequent myocardial infarction of other sites
0.000 0.380 0.620
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.380 0.620
K74.5 Biliary cirrhosis, unspecified
0.000 0.380 0.620
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.382 0.618
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.382 0.618
M70.1 Bursitis of hand
0.000 0.382 0.618
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.382 0.618
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.383 0.617
G25.3 Myoclonus
0.616 0.384 0.000
E11.6 With other specified complications
0.000 0.387 0.613
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.611 0.389 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.389 0.611
G03 Meningitis due to other and unspecified causes
0.609 0.391 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.391 0.609
G81 Hemiplegia
0.608 0.392 0.000
I05-I09 Chronic rheumatic heart diseases
0.000 0.393 0.607
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.393 0.606
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.393 0.606
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.393 0.606
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.393 0.606
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.393 0.606
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.393 0.606
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.393 0.606
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.393 0.606
G41.0 Grand mal status epilepticus
0.606 0.394 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.394 0.606
G44.8 Other specified headache syndromes
0.605 0.395 0.000
M79.79 Fibromyalgia (Site unspecified)
0.000 0.396 0.604
G06 Intracranial and intraspinal abscess and granuloma
0.601 0.399 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.399 0.601
E89.3 Postprocedural hypopituitarism
0.000 0.400 0.600
M75.9 Shoulder lesion, unspecified
0.000 0.402 0.598
I42 Cardiomyopathy
0.000 0.402 0.598
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.402 0.598
I36 Nonrheumatic tricuspid valve disorders
0.000 0.403 0.597
E83.5 Disorders of calcium metabolism
0.592 0.403 0.005
M11.2 Other chondrocalcinosis
0.000 0.403 0.597
M00-M03 Infectious arthropathies
0.000 0.404 0.596
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.405 0.595
M77.18 Lateral epicondylitis-Other
0.000 0.405 0.595
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.405 0.595
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.405 0.595
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.405 0.595
M77.14 Lateral epicondylitis-Hand
0.000 0.405 0.595
M77.13 Lateral epicondylitis-Forearm
0.000 0.405 0.595
M77.11 Lateral epicondylitis-Shldr region
0.000 0.405 0.595
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.405 0.595
G25.6 Drug-induced tics and other tics of organic origin
0.595 0.405 0.000
G25.5 Other chorea
0.595 0.405 0.000
G25.4 Drug-induced chorea
0.595 0.405 0.000
G25.1 Drug-induced tremor
0.595 0.405 0.000
M94 Other disorders of cartilage
0.000 0.405 0.595
I24.1 Dressler's syndrome
0.000 0.405 0.594
E88 Other metabolic disorders
0.000 0.407 0.593
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.407 0.593
M06.38 Rheumatoid nodule (Other)
0.000 0.407 0.593
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.407 0.593
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.407 0.593
M06.33 Rheumatoid nodule (Forearm)
0.000 0.407 0.593
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.407 0.593
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.407 0.593
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.407 0.593
E89.2 Postprocedural hypoparathyroidism
0.000 0.409 0.591
K73 Chronic hepatitis, not elsewhere classified
0.000 0.409 0.591
K74.6 Other and unspecified cirrhosis of liver
0.000 0.411 0.589
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.411 0.589
M70.3 Other bursitis of elbow
0.000 0.412 0.588
M70.6 Trochanteric bursitis
0.000 0.414 0.586
M77.4 Metatarsalgia
0.000 0.414 0.586
G47.8 Other sleep disorders
0.585 0.415 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.585 0.415 0.000
K72.9 Hepatic failure, unspecified
0.000 0.416 0.584
M07.38 Other psoriatic arthropathies (Other)
0.000 0.417 0.583
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.417 0.583
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.417 0.583
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.417 0.583
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.417 0.583
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.417 0.583
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.417 0.583
E83.9 Disorder of mineral metabolism, unspecified
0.542 0.417 0.041
E83.8 Other disorders of mineral metabolism
0.542 0.417 0.041
E83.2 Disorders of zinc metabolism
0.542 0.417 0.041
E83.0 Disorders of copper metabolism
0.542 0.417 0.041
G40.7 Petit mal, unspecified, without grand mal seizures
0.583 0.417 0.000
E06.3 Autoimmune thyroiditis
0.000 0.418 0.582
G04 Encephalitis, myelitis and encephalomyelitis
0.581 0.419 0.000
H35.9 Retinal disorder, unspecified
0.000 0.419 0.581
G40.8 Other epilepsy
0.581 0.419 0.000
M70.2 Olecranon bursitis
0.000 0.420 0.580
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.421 0.579
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.421 0.579
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.422 0.577
I31.3 Pericardial effusion (noninflammatory)
0.000 0.423 0.577
G24 Dystonia
0.576 0.424 0.000
M70.49 Prepatellar bursitis-Site unspec
0.000 0.425 0.574
M70.48 Prepatellar bursitis-Other
0.000 0.425 0.574
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.425 0.574
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.425 0.574
M70.44 Prepatellar bursitis-Hand
0.000 0.425 0.574
M70.43 Prepatellar bursitis-Forearm
0.000 0.425 0.574
M70.42 Prepatellar bursitis-Upper arm
0.000 0.425 0.574
M70.41 Prepatellar bursitis-Shldr region
0.000 0.425 0.574
M70.40 Prepatellar bursitis-Mult sites
0.000 0.425 0.574
M76 Enthesopathies of lower limb, excluding foot
0.000 0.426 0.574
G83.4 Cauda equina syndrome
0.571 0.429 0.000
M60-M63 Disorders of muscles
0.000 0.429 0.571
I45 Other conduction disorders
0.000 0.430 0.570
M79.1 Myalgia
0.000 0.435 0.565
M71.2 Synovial cyst of popliteal space [Baker]
0.000 0.436 0.564
M65.8 Other synovitis and tenosynovitis
0.000 0.436 0.564
G93 Other disorders of brain
0.564 0.436 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.437 0.563
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.437 0.563
K90.1 Tropical sprue
0.000 0.437 0.563
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.562 0.438 0.000
G46.6 Pure sensory lacunar syndrome
0.562 0.438 0.000
G46.5 Pure motor lacunar syndrome
0.562 0.438 0.000
G46.3 Brain stem stroke syndrome
0.562 0.438 0.000
G46.2 Posterior cerebral artery syndrome
0.562 0.438 0.000
G46.1 Anterior cerebral artery syndrome
0.562 0.438 0.000
G46.0 Middle cerebral artery syndrome
0.562 0.438 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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