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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130071
log Bayes Factor = 117.396
Chromosome 6   position 31,594,628  (GRCh37) Explore rs3130071 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
E11.9 Without complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.003 0.997
I25.1 Atherosclerotic heart disease
0.000 0.004 0.996
I20.9 Angina pectoris, unspecified
0.000 0.004 0.996
G20-G26 Extrapyramidal and movement disorders
0.995 0.005 0.000
H43-H45 Disorders of vitreous body and globe
0.000 0.006 0.994
E10.4 With neurological complications
0.000 0.006 0.994
G20 Parkinson's disease
0.994 0.006 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.993 0.007 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.007 0.993
E70-E90 Metabolic disorders
0.000 0.007 0.992
H43 Disorders of vitreous body
0.000 0.007 0.993
E14.9 Without complications
0.000 0.008 0.992
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.010 0.990
I22 Subsequent myocardial infarction
0.000 0.010 0.990
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.012 0.988
L43 Lichen planus
0.000 0.012 0.988
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.014 0.986
H43.8 Other disorders of vitreous body
0.000 0.014 0.986
E14.3 With ophthalmic complications
0.000 0.015 0.985
E16 Other disorders of pancreatic internal secretion
0.000 0.017 0.983
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.020 0.980
L43.9 Lichen planus, unspecified
0.000 0.022 0.978
E16.2 Hypoglycaemia, unspecified
0.000 0.022 0.978
I20.0 Unstable angina
0.000 0.024 0.976
J45.9 Asthma, unspecified
0.000 0.026 0.974
I25.5 Ischaemic cardiomyopathy
0.000 0.036 0.964
M45-M49 Spondylopathies
0.000 0.037 0.963
M45 Ankylosing spondylitis
0.000 0.039 0.961
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.039 0.961
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.043 0.957
I30-I52 Other forms of heart disease
0.000 0.045 0.955
I47 Paroxysmal tachycardia
0.000 0.050 0.950
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.055 0.945
H35 Other retinal disorders
0.000 0.056 0.944
I24 Other acute ischaemic heart diseases
0.000 0.056 0.944
E07 Other disorders of thyroid
0.000 0.057 0.943
H43.3 Other vitreous opacities
0.000 0.058 0.942
M70-M79 Other soft tissue disorders
0.000 0.059 0.941
I12 Hypertensive renal disease
0.000 0.070 0.930
I51 Complications and ill-defined descriptions of heart disease
0.000 0.073 0.927
H35.8 Other specified retinal disorders
0.000 0.075 0.925
I47.1 Supraventricular tachycardia
0.000 0.079 0.921
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.081 0.919
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.082 0.918
I51.8 Other ill-defined heart diseases
0.000 0.083 0.917
I35 Nonrheumatic aortic valve disorders
0.000 0.085 0.915
H34 Retinal vascular occlusions
0.000 0.087 0.913
I35.0 Aortic (valve) stenosis
0.000 0.088 0.912
M05 Seropositive rheumatoid arthritis
0.000 0.095 0.905
M07 Psoriatic and enteropathic arthropathies
0.000 0.098 0.902
I15 Secondary hypertension
0.000 0.102 0.898
E07.9 Disorder of thyroid, unspecified
0.000 0.104 0.896
E11.3 With ophthalmic complications
0.000 0.107 0.893
K90 Intestinal malabsorption
0.000 0.110 0.890
E78.2 Mixed hyperlipidaemia
0.000 0.110 0.890
G37.8 Other specified demyelinating diseases of central nervous system
0.890 0.110 0.000
E10.5 With peripheral circulatory complications
0.000 0.111 0.889
G40-G47 Episodic and paroxysmal disorders
0.889 0.111 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.115 0.885
I25.2 Old myocardial infarction
0.000 0.116 0.884
I12.9 Hypertensive renal disease without renal failure
0.000 0.118 0.882
G30-G32 Other degenerative diseases of the nervous system
0.882 0.118 0.000
I47.2 Ventricular tachycardia
0.000 0.119 0.881
E11.1 With ketoacidosis
0.000 0.124 0.876
M75 Shoulder lesions
0.000 0.127 0.873
E78.8 Other disorders of lipoprotein metabolism
0.000 0.130 0.870
E13 Other specified diabetes mellitus
0.000 0.131 0.869
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.133 0.867
I20.1 Angina pectoris with documented spasm
0.000 0.135 0.865
M65-M68 Disorders of synovium and tendon
0.000 0.139 0.861
E10.2 With renal complications
0.000 0.144 0.856
M75.0 Adhesive capsulitis of shoulder
0.000 0.145 0.855
G00-G09 Inflammatory diseases of the central nervous system
0.853 0.146 0.000
K90-K93 Other diseases of the digestive system
0.000 0.147 0.853
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.149 0.851
Chapter XI Diseases of the digestive system
0.000 0.150 0.850
K70-K77 Diseases of liver
0.000 0.159 0.841
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.160 0.840
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.162 0.838
K74 Fibrosis and cirrhosis of liver
0.000 0.165 0.835
M77 Other enthesopathies
0.000 0.165 0.835
G25 Other extrapyramidal and movement disorders
0.835 0.165 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.166 0.834
M07.3 Other psoriatic arthropathies
0.000 0.167 0.833
E11.2 With renal complications
0.000 0.167 0.833
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.172 0.828
I15.1 Hypertension secondary to other renal disorders
0.000 0.175 0.825
K74.3 Primary biliary cirrhosis
0.000 0.176 0.824
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.176 0.824
M06.3 Rheumatoid nodule
0.000 0.178 0.822
H34.8 Other retinal vascular occlusions
0.000 0.178 0.822
I25.3 Aneurysm of heart
0.000 0.184 0.816
E11.0 With coma
0.000 0.192 0.808
M65 Synovitis and tenosynovitis
0.000 0.194 0.806
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.196 0.804
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.199 0.801
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.203 0.797
E83 Disorders of mineral metabolism
0.731 0.204 0.065
G46 Vascular syndromes of brain in cerebrovascular diseases
0.790 0.209 0.000
L43.8 Other lichen planus
0.000 0.211 0.789
I51.9 Heart disease, unspecified
0.000 0.213 0.787
H43.9 Disorder of vitreous body, unspecified
0.000 0.215 0.785
L40.8 Other psoriasis
0.000 0.217 0.783
M77.1 Lateral epicondylitis
0.000 0.219 0.780
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.223 0.777
E74 Other disorders of carbohydrate metabolism
0.000 0.224 0.776
E13.9 Without complications
0.000 0.225 0.775
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.227 0.773
G40 Epilepsy
0.771 0.229 0.000
M70.4 Prepatellar bursitis
0.000 0.231 0.769
H35.2 Other proliferative retinopathy
0.000 0.233 0.767
H35.6 Retinal haemorrhage
0.000 0.234 0.766
E05.9 Thyrotoxicosis, unspecified
0.000 0.234 0.766
M11 Other crystal arthropathies
0.000 0.235 0.765
I11 Hypertensive heart disease
0.000 0.237 0.763
G30 Alzheimer's disease
0.762 0.238 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.240 0.760
K72 Hepatic failure, not elsewhere classified
0.000 0.240 0.760
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.241 0.759
H35.4 Peripheral retinal degeneration
0.000 0.243 0.757
E78.4 Other hyperlipidaemia
0.000 0.243 0.757
E06 Thyroiditis
0.000 0.246 0.754
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.247 0.753
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.252 0.748
E14.4 With neurological complications
0.000 0.254 0.746
E03.8 Other specified hypothyroidism
0.000 0.256 0.744
I23 Certain current complications following acute myocardial infarction
0.000 0.257 0.743
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.259 0.741
E40-E46 Malnutrition
0.000 0.264 0.736
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.735 0.265 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.268 0.732
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.268 0.731
M75.2 Bicipital tendinitis
0.000 0.269 0.731
I51.0 Cardiac septal defect, acquired
0.000 0.270 0.730
G80-G83 Cerebral palsy and other paralytic syndromes
0.730 0.270 0.000
G44 Other headache syndromes
0.729 0.271 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.271 0.729
G41 Status epilepticus
0.729 0.271 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.273 0.727
M14 Arthropathies in other diseases classified elsewhere
0.000 0.276 0.724
H34.2 Other retinal artery occlusions
0.000 0.279 0.721
H35.5 Hereditary retinal dystrophy
0.000 0.279 0.721
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.280 0.720
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.281 0.719
G47 Sleep disorders
0.719 0.281 0.000
L40.0 Psoriasis vulgaris
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.716
H30 Chorioretinal inflammation
0.000 0.283 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
K74.5 Biliary cirrhosis, unspecified
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.715
L41 Parapsoriasis
0.000 0.284 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.715
G37.5 Concentric sclerosis [Balo]
0.715 0.285 0.000
G37.4 Subacute necrotising myelitis
0.715 0.285 0.000
G37.2 Central pontine myelinolysis
0.715 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.285 0.000
G37.0 Diffuse sclerosis
0.715 0.285 0.000
E07.8 Other specified disorders of thyroid
0.000 0.285 0.715
E78.6 Lipoprotein deficiency
0.000 0.285 0.715
E78.3 Hyperchylomicronaemia
0.000 0.285 0.715
I46 Cardiac arrest
0.000 0.286 0.714
G23 Other degenerative diseases of basal ganglia
0.714 0.286 0.000
G21 Secondary Parkinsonism
0.714 0.286 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.714 0.286 0.000
G22 Parkinsonism in diseases classified elsewhere
0.714 0.286 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.287 0.713
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.711
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.711
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.711
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.711
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.711
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.711
H43.2 Crystalline deposits in vitreous body
0.000 0.288 0.712
H43.0 Vitreous prolapse
0.000 0.288 0.712
E15 Nondiabetic hypoglycaemic coma
0.000 0.290 0.710
L43.3 Subacute (active) lichen planus
0.000 0.292 0.708
L43.2 Lichenoid drug reaction
0.000 0.292 0.708
L43.1 Bullous lichen planus
0.000 0.292 0.708
L43.0 Hypertrophic lichen planus
0.000 0.292 0.708
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.293 0.707
I47.0 Reentry ventricular arrhythmia
0.000 0.294 0.706
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.295 0.705
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.295 0.705
E16.4 Abnormal secretion of gastrin
0.000 0.295 0.705
E16.3 Increased secretion of glucagon
0.000 0.295 0.705
E16.1 Other hypoglycaemia
0.000 0.295 0.705
M06.4 Inflammatory polyarthropathy
0.000 0.295 0.705
G00 Bacterial meningitis, not elsewhere classified
0.703 0.297 0.000
M75.4 Impingement syndrome of shoulder
0.000 0.298 0.702
G09 Sequelae of inflammatory diseases of central nervous system
0.700 0.299 0.000
K74.6 Other and unspecified cirrhosis of liver
0.000 0.301 0.699
I31 Other diseases of pericardium
0.000 0.301 0.699
K73 Chronic hepatitis, not elsewhere classified
0.000 0.301 0.699
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.698 0.302 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.304 0.696
E79 Disorders of purine and pyrimidine metabolism
0.000 0.304 0.696
E11.5 With peripheral circulatory complications
0.000 0.305 0.695
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.306 0.694
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.306 0.694
H34.1 Central retinal artery occlusion
0.000 0.309 0.691
M49 Spondylopathies in diseases classified elsewhere
0.000 0.310 0.690
E14.6 With other specified complications
0.000 0.310 0.690
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.311 0.689
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.311 0.689
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.311 0.689
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.311 0.689
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.311 0.689
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.311 0.689
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.311 0.689
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.311 0.689
M75.3 Calcific tendinitis of shoulder
0.000 0.311 0.689
M71 Other bursopathies
0.000 0.312 0.688
G46.7 Other lacunar syndromes
0.686 0.314 0.000
I52 Other heart disorders in diseases classified elsewhere
0.000 0.315 0.684
I48 Atrial fibrillation and flutter
0.000 0.315 0.684
I41 Myocarditis in diseases classified elsewhere
0.000 0.315 0.684
I40 Acute myocarditis
0.000 0.315 0.684
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.315 0.684
I32 Pericarditis in diseases classified elsewhere
0.000 0.315 0.684
L42 Pityriasis rosea
0.000 0.317 0.683
G40.9 Epilepsy, unspecified
0.681 0.319 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.320 0.680
E83.3 Disorders of phosphorus metabolism
0.661 0.320 0.019
M06.0 Seronegative rheumatoid arthritis
0.000 0.323 0.677
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.323 0.677
H35.1 Retinopathy of prematurity
0.000 0.323 0.677
I44 Atrioventricular and left bundle-branch block
0.000 0.323 0.677
E07.1 Dyshormogenetic goitre
0.000 0.324 0.676
E07.0 Hypersecretion of calcitonin
0.000 0.324 0.676
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.324 0.676
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.324 0.676
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.325 0.674
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.326 0.673
K90.9 Intestinal malabsorption, unspecified
0.000 0.327 0.673
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.327 0.000
G90-G99 Other disorders of the nervous system
0.672 0.328 0.000
E11.8 With unspecified complications
0.000 0.329 0.671
M46 Other inflammatory spondylopathies
0.000 0.330 0.670
H31 Other disorders of choroid
0.000 0.332 0.668
I25.4 Coronary artery aneurysm
0.000 0.333 0.667
G25.8 Other specified extrapyramidal and movement disorders
0.666 0.333 0.000
I51.5 Myocardial degeneration
0.000 0.335 0.665
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.335 0.665
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.337 0.663
M77.5 Other enthesopathy of foot
0.000 0.339 0.661
M12 Other specific arthropathies
0.000 0.341 0.659
K72.9 Hepatic failure, unspecified
0.000 0.345 0.655
H34.0 Transient retinal artery occlusion
0.000 0.345 0.654
L40.3 Pustulosis palmaris et plantaris
0.000 0.347 0.653
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.652 0.348 0.000
H35.7 Separation of retinal layers
0.000 0.348 0.652
I35.8 Other aortic valve disorders
0.000 0.349 0.650
G25.9 Extrapyramidal and movement disorder, unspecified
0.649 0.351 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.351 0.649
I12.0 Hypertensive renal disease with renal failure
0.000 0.351 0.649
M05.8 Other seropositive rheumatoid arthritis
0.000 0.351 0.649
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.351 0.649
M05.2 Rheumatoid vasculitis
0.000 0.351 0.649
M05.1 Rheumatoid lung disease
0.000 0.351 0.649
M05.0 Felty's syndrome
0.000 0.351 0.649
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.648 0.352 0.000
G30.9 Alzheimer's disease, unspecified
0.647 0.353 0.000
M07.6 Other enteropathic arthropathies
0.000 0.353 0.647
M07.5 Arthropathy in ulcerative colitis
0.000 0.353 0.647
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.353 0.647
M07.2 Psoriatic spondylitis
0.000 0.353 0.647
M07.1 Arthritis mutilans
0.000 0.353 0.647
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.353 0.647
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.354 0.646
I15.9 Seconday hypertension, unspecified
0.000 0.356 0.644
I15.8 Other secondary hypertension
0.000 0.356 0.644
I15.2 Hypertension secondary to endocrine disorders
0.000 0.356 0.644
I15.0 Renovascular hypertension
0.000 0.356 0.644
G31.9 Degenerative disease of nervous system, unspecified
0.643 0.357 0.000
E11.6 With other specified complications
0.000 0.357 0.643
E84 Cystic fibrosis
0.000 0.357 0.642
K72.0 Acute and subacute hepatic failure
0.000 0.359 0.641
G46.4 Cerebellar stroke syndrome
0.640 0.360 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.640 0.360 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.360 0.639
I45 Other conduction disorders
0.000 0.361 0.639
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.361 0.639
K90.3 Pancreatic steatorrhoea
0.000 0.362 0.638
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.362 0.638
K90.1 Tropical sprue
0.000 0.362 0.638
G03 Meningitis due to other and unspecified causes
0.638 0.362 0.000
I21 Acute myocardial infarction
0.000 0.362 0.638
H34.9 Retinal vascular occlusion, unspecified
0.000 0.363 0.637
G25.2 Other specified forms of tremor
0.636 0.364 0.000
M91-M94 Chondropathies
0.000 0.364 0.636
L10-L14 Bullous disorders
0.000 0.366 0.634
G44.8 Other specified headache syndromes
0.631 0.369 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.629 0.371 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.373 0.627
M75.8 Other shoulder lesions
0.000 0.374 0.626
E13.8 With unspecified complications
0.000 0.377 0.623
E13.7 With multiple complications
0.000 0.377 0.623
E13.6 With other specified complications
0.000 0.377 0.623
E13.5 With peripheral circulatory complications
0.000 0.377 0.623
E13.4 With neurological complications
0.000 0.377 0.623
E13.3 With ophthalmic complications
0.000 0.377 0.623
E13.2 With renal complications
0.000 0.377 0.623
E13.1 With ketoacidosis
0.000 0.377 0.623
E13.0 With coma
0.000 0.377 0.623
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.377 0.623
K75 Other inflammatory liver diseases
0.000 0.377 0.623
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.378 0.622
E05.5 Thyroid crisis or storm
0.000 0.379 0.621
E05.4 Thyrotoxicosis factitia
0.000 0.379 0.621
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.379 0.621
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.379 0.621
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.379 0.621
I22.8 Subsequent myocardial infarction of other sites
0.000 0.380 0.620
G25.3 Myoclonus
0.620 0.380 0.000
G30.8 Other Alzheimer's disease
0.619 0.380 0.000
E06.3 Autoimmune thyroiditis
0.000 0.382 0.618
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.383 0.617
H43.1 Vitreous haemorrhage
0.000 0.383 0.617
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.387 0.613
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.612 0.388 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.612 0.388 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.389 0.611
G40.7 Petit mal, unspecified, without grand mal seizures
0.610 0.390 0.000
I36 Nonrheumatic tricuspid valve disorders
0.000 0.391 0.609
I42 Cardiomyopathy
0.000 0.391 0.609
G04 Encephalitis, myelitis and encephalomyelitis
0.608 0.392 0.000
M65.8 Other synovitis and tenosynovitis
0.000 0.392 0.608
I46.9 Cardiac arrest, unspecified
0.000 0.395 0.605
M77.0 Medial epicondylitis
0.000 0.396 0.604
M70.7 Other bursitis of hip
0.000 0.397 0.603
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.397 0.603
I31.3 Pericardial effusion (noninflammatory)
0.000 0.397 0.603
K77 Liver disorders in diseases classified elsewhere
0.000 0.397 0.603
K71 Toxic liver disease
0.000 0.397 0.603
H55-H59 Other disorders of eye and adnexa
0.000 0.398 0.602
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.399 0.601
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.399 0.601
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.399 0.601
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.399 0.601
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.399 0.601
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.399 0.601
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.399 0.601
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.399 0.601
M70.5 Other bursitis of knee
0.000 0.400 0.600
K74.4 Secondary biliary cirrhosis
0.000 0.401 0.599
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.401 0.599
K74.1 Hepatic sclerosis
0.000 0.401 0.599
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.401 0.599
M77.3 Calcaneal spur
0.000 0.401 0.599
M77.2 Periarthritis of wrist
0.000 0.401 0.599
I44.0 Atrioventricular block, first degree
0.000 0.401 0.599
G25.6 Drug-induced tics and other tics of organic origin
0.598 0.402 0.000
G25.5 Other chorea
0.598 0.402 0.000
G25.4 Drug-induced chorea
0.598 0.402 0.000
G25.1 Drug-induced tremor
0.598 0.402 0.000
M11.2 Other chondrocalcinosis
0.000 0.402 0.598
M07.38 Other psoriatic arthropathies (Other)
0.000 0.403 0.597
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.403 0.597
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.403 0.597
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.403 0.597
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.403 0.597
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.403 0.597
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.403 0.597
K90.8 Other intestinal malabsorption
0.000 0.403 0.597
M00-M03 Infectious arthropathies
0.000 0.404 0.595
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.407 0.593
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.407 0.593
M70.1 Bursitis of hand
0.000 0.407 0.593
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.407 0.593
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.407 0.593
G47.8 Other sleep disorders
0.592 0.408 0.000
G41.0 Grand mal status epilepticus
0.592 0.408 0.000
K50-K52 Noninfective enteritis and colitis
0.023 0.409 0.569
G24 Dystonia
0.591 0.409 0.000
E88 Other metabolic disorders
0.000 0.410 0.590
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.411 0.589
M06.38 Rheumatoid nodule (Other)
0.000 0.411 0.589
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.411 0.589
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.411 0.589
M06.33 Rheumatoid nodule (Forearm)
0.000 0.411 0.589
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.411 0.589
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.411 0.589
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.411 0.589
E89.3 Postprocedural hypopituitarism
0.000 0.411 0.589
I44.3 Other and unspecified atrioventricular block
0.000 0.413 0.587
G00.9 Bacterial meningitis, unspecified
0.586 0.414 0.000
I24.1 Dressler's syndrome
0.000 0.415 0.585
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.415 0.585
H40-H42 Glaucoma
0.000 0.416 0.584
G83 Other paralytic syndromes
0.583 0.417 0.000
M60-M63 Disorders of muscles
0.000 0.419 0.580
M65.1 Other infective (teno)synovitis
0.000 0.420 0.580
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.420 0.580
M71.2 Synovial cyst of popliteal space [Baker]
0.000 0.422 0.578
M65.2 Calcific tendinitis
0.000 0.422 0.578
M65.0 Abscess of tendon sheath
0.000 0.422 0.578
G01 Meningitis in bacterial diseases classified elsewhere
0.576 0.424 0.000
G47.3 Sleep apnoea
0.573 0.427 0.000
H35.9 Retinal disorder, unspecified
0.000 0.429 0.571
E83.9 Disorder of mineral metabolism, unspecified
0.524 0.429 0.046
E83.8 Other disorders of mineral metabolism
0.524 0.429 0.046
E83.2 Disorders of zinc metabolism
0.524 0.429 0.046
E83.0 Disorders of copper metabolism
0.524 0.429 0.046
I05-I09 Chronic rheumatic heart diseases
0.000 0.430 0.570
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.430 0.570
G40.8 Other epilepsy
0.567 0.433 0.000
I42.2 Other hypertrophic cardiomyopathy
0.000 0.433 0.567
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.567 0.433 0.000
G46.6 Pure sensory lacunar syndrome
0.567 0.433 0.000
G46.5 Pure motor lacunar syndrome
0.567 0.433 0.000
G46.3 Brain stem stroke syndrome
0.567 0.433 0.000
G46.2 Posterior cerebral artery syndrome
0.567 0.433 0.000
G46.1 Anterior cerebral artery syndrome
0.567 0.433 0.000
G46.0 Middle cerebral artery syndrome
0.567 0.433 0.000
M70.3 Other bursitis of elbow
0.000 0.435 0.565
G25.0 Essential tremor
0.564 0.436 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.437 0.563
G40.5 Special epileptic syndromes
0.560 0.440 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.440 0.560
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.440 0.560
M77.18 Lateral epicondylitis-Other
0.000 0.440 0.560
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.440 0.560
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.440 0.560
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.440 0.560
M77.14 Lateral epicondylitis-Hand
0.000 0.440 0.560
M77.13 Lateral epicondylitis-Forearm
0.000 0.440 0.560
M77.11 Lateral epicondylitis-Shldr region
0.000 0.440 0.560
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.440 0.560

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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