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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130287
log Bayes Factor = 140.271
Chromosome 6   position 32,050,544  (GRCh37) Explore rs3130287 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
E14.9 Without complications
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
G37.9 Demyelinating disease of central nervous system, unspecified
0.998 0.002 0.000
I20 Angina pectoris
0.000 0.003 0.997
E10.4 With neurological complications
0.000 0.003 0.997
J45.9 Asthma, unspecified
0.000 0.003 0.997
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.005 0.995
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.005 0.995
K70-K77 Diseases of liver
0.000 0.005 0.995
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.006 0.994
L43 Lichen planus
0.000 0.006 0.994
E70-E90 Metabolic disorders
0.000 0.007 0.993
E14.3 With ophthalmic complications
0.000 0.008 0.992
I22 Subsequent myocardial infarction
0.000 0.009 0.991
M05 Seropositive rheumatoid arthritis
0.000 0.010 0.990
I30-I52 Other forms of heart disease
0.000 0.011 0.989
I20.0 Unstable angina
0.000 0.011 0.989
L43.9 Lichen planus, unspecified
0.000 0.011 0.989
I47 Paroxysmal tachycardia
0.000 0.012 0.988
K74 Fibrosis and cirrhosis of liver
0.000 0.015 0.985
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.016 0.984
I35.0 Aortic (valve) stenosis
0.000 0.016 0.984
I35 Nonrheumatic aortic valve disorders
0.000 0.017 0.983
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.017 0.983
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.018 0.982
H43-H45 Disorders of vitreous body and globe
0.000 0.022 0.978
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.022 0.978
I47.1 Supraventricular tachycardia
0.000 0.022 0.978
K80 Cholelithiasis
0.000 0.027 0.973
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.028 0.972
H43 Disorders of vitreous body
0.000 0.029 0.971
I20.9 Angina pectoris, unspecified
0.000 0.029 0.971
H40-H42 Glaucoma
0.000 0.030 0.970
K74.3 Primary biliary cirrhosis
0.000 0.033 0.967
I25.1 Atherosclerotic heart disease
0.000 0.033 0.967
K81 Cholecystitis
0.000 0.034 0.966
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.035 0.964
E83 Disorders of mineral metabolism
0.952 0.038 0.010
I25.5 Ischaemic cardiomyopathy
0.000 0.039 0.961
K82 Other diseases of gallbladder
0.000 0.040 0.960
H34 Retinal vascular occlusions
0.000 0.041 0.959
E07 Other disorders of thyroid
0.000 0.041 0.959
I24 Other acute ischaemic heart diseases
0.000 0.041 0.959
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.042 0.958
E10.5 With peripheral circulatory complications
0.000 0.046 0.954
H40 Glaucoma
0.000 0.049 0.951
H40.9 Glaucoma, unspecified
0.000 0.050 0.950
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.052 0.948
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.052 0.948
K81.1 Chronic cholecystitis
0.000 0.062 0.938
K72 Hepatic failure, not elsewhere classified
0.000 0.062 0.938
H43.3 Other vitreous opacities
0.000 0.063 0.937
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.065 0.935
E07.9 Disorder of thyroid, unspecified
0.000 0.068 0.932
K82.8 Other specified diseases of gallbladder
0.000 0.071 0.929
M07 Psoriatic and enteropathic arthropathies
0.000 0.079 0.921
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.082 0.918
E11.3 With ophthalmic complications
0.000 0.084 0.916
H43.8 Other disorders of vitreous body
0.000 0.087 0.913
K81.9 Cholecystitis, unspecified
0.000 0.088 0.912
I46 Cardiac arrest
0.000 0.091 0.909
E11.1 With ketoacidosis
0.000 0.100 0.900
H34.2 Other retinal artery occlusions
0.000 0.101 0.899
E83.3 Disorders of phosphorus metabolism
0.896 0.101 0.002
K51 Ulcerative colitis
0.896 0.104 0.000
K51.9 Ulcerative colitis, unspecified
0.894 0.106 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.889 0.111 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.111 0.889
K51.3 Ulcerative (chronic) rectosigmoiditis
0.884 0.115 0.000
I47.2 Ventricular tachycardia
0.000 0.116 0.884
K82.1 Hydrops of gallbladder
0.000 0.117 0.883
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.124 0.876
E83.5 Disorders of calcium metabolism
0.874 0.126 0.001
I46.9 Cardiac arrest, unspecified
0.000 0.127 0.873
E11.2 With renal complications
0.000 0.127 0.873
I25.2 Old myocardial infarction
0.000 0.128 0.872
K74.6 Other and unspecified cirrhosis of liver
0.000 0.129 0.871
E10.2 With renal complications
0.000 0.132 0.868
M07.3 Other psoriatic arthropathies
0.000 0.135 0.865
M65-M68 Disorders of synovium and tendon
0.000 0.137 0.863
E11.5 With peripheral circulatory complications
0.000 0.141 0.859
K75 Other inflammatory liver diseases
0.000 0.143 0.857
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.145 0.855
K72.9 Hepatic failure, unspecified
0.000 0.147 0.853
K73 Chronic hepatitis, not elsewhere classified
0.000 0.149 0.851
I47.0 Reentry ventricular arrhythmia
0.000 0.150 0.850
E03.8 Other specified hypothyroidism
0.000 0.153 0.847
I15 Secondary hypertension
0.000 0.157 0.843
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.160 0.840
Chapter VI Diseases of the nervous system
0.836 0.160 0.004
E11.0 With coma
0.000 0.162 0.838
E13 Other specified diabetes mellitus
0.000 0.168 0.832
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.831 0.169 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.171 0.829
E78.2 Mixed hyperlipidaemia
0.000 0.174 0.826
K50-K52 Noninfective enteritis and colitis
0.033 0.175 0.792
M06.3 Rheumatoid nodule
0.000 0.176 0.824
M65 Synovitis and tenosynovitis
0.000 0.179 0.821
E06 Thyroiditis
0.000 0.186 0.814
K72.0 Acute and subacute hepatic failure
0.000 0.188 0.812
H34.8 Other retinal vascular occlusions
0.000 0.189 0.811
E16.1 Other hypoglycaemia
0.000 0.190 0.810
I12 Hypertensive renal disease
0.000 0.191 0.809
K51.8 Other ulcerative colitis
0.809 0.191 0.000
K74.5 Biliary cirrhosis, unspecified
0.000 0.193 0.807
M06.0 Seronegative rheumatoid arthritis
0.000 0.195 0.805
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.199 0.801
I20.1 Angina pectoris with documented spasm
0.000 0.200 0.800
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.201 0.799
L43.8 Other lichen planus
0.000 0.202 0.798
E83.9 Disorder of mineral metabolism, unspecified
0.784 0.210 0.006
L40.8 Other psoriasis
0.000 0.212 0.787
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.215 0.785
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.216 0.784
I25.3 Aneurysm of heart
0.000 0.219 0.780
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.221 0.779
K80.8 Other cholelithiasis
0.000 0.221 0.779
K51.2 Ulcerative (chronic) proctitis
0.774 0.226 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.226 0.774
E40-E46 Malnutrition
0.000 0.232 0.768
G20-G26 Extrapyramidal and movement disorders
0.767 0.232 0.001
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.233 0.767
L40.0 Psoriasis vulgaris
0.000 0.233 0.767
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.235 0.765
E14.4 With neurological complications
0.000 0.235 0.765
H40.1 Primary open-angle glaucoma
0.000 0.238 0.762
E74 Other disorders of carbohydrate metabolism
0.000 0.240 0.760
G80-G83 Cerebral palsy and other paralytic syndromes
0.757 0.242 0.001
I45 Other conduction disorders
0.000 0.243 0.757
H30 Chorioretinal inflammation
0.000 0.244 0.756
I31 Other diseases of pericardium
0.000 0.248 0.752
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.248 0.752
G30-G32 Other degenerative diseases of the nervous system
0.749 0.249 0.001
H43.9 Disorder of vitreous body, unspecified
0.000 0.251 0.749
E88 Other metabolic disorders
0.000 0.252 0.748
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.253 0.747
K75.4 Autoimmune hepatitis
0.000 0.254 0.746
E78.1 Pure hyperglyceridaemia
0.000 0.255 0.745
M70-M79 Other soft tissue disorders
0.000 0.257 0.743
K51.5 Mucosal proctocolitis
0.741 0.259 0.000
G20 Parkinson's disease
0.740 0.260 0.000
H43.2 Crystalline deposits in vitreous body
0.000 0.264 0.736
M14 Arthropathies in other diseases classified elsewhere
0.000 0.264 0.736
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.267 0.733
E11.6 With other specified complications
0.000 0.267 0.733
I25.4 Coronary artery aneurysm
0.000 0.269 0.731
H34.1 Central retinal artery occlusion
0.000 0.269 0.730
I23 Certain current complications following acute myocardial infarction
0.000 0.274 0.726
J45 Asthma
0.000 0.275 0.725
E78.8 Other disorders of lipoprotein metabolism
0.000 0.276 0.724
M45-M49 Spondylopathies
0.000 0.277 0.723
I30 Acute pericarditis
0.000 0.278 0.722
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.281 0.719
K50 Crohn's disease [regional enteritis]
0.002 0.281 0.717
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.281 0.719
L42 Pityriasis rosea
0.000 0.282 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.716
E16.3 Increased secretion of glucagon
0.000 0.283 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.287 0.713
K77 Liver disorders in diseases classified elsewhere
0.000 0.287 0.713
K71 Toxic liver disease
0.000 0.287 0.713
I35.8 Other aortic valve disorders
0.000 0.287 0.713
E78.6 Lipoprotein deficiency
0.000 0.287 0.713
E78.3 Hyperchylomicronaemia
0.000 0.287 0.713
L43.3 Subacute (active) lichen planus
0.000 0.287 0.713
L43.2 Lichenoid drug reaction
0.000 0.287 0.713
L43.1 Bullous lichen planus
0.000 0.287 0.713
L43.0 Hypertrophic lichen planus
0.000 0.287 0.713
E13.9 Without complications
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.712
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.712
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.288 0.712
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.712
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.712
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.712
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.712
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.288 0.712
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.289 0.711
K82.2 Perforation of gallbladder
0.000 0.290 0.710
M05.8 Other seropositive rheumatoid arthritis
0.000 0.290 0.710
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.290 0.710
M05.2 Rheumatoid vasculitis
0.000 0.290 0.710
M05.1 Rheumatoid lung disease
0.000 0.290 0.710
M05.0 Felty's syndrome
0.000 0.290 0.710
I52 Other heart disorders in diseases classified elsewhere
0.000 0.291 0.709
I48 Atrial fibrillation and flutter
0.000 0.291 0.709
I41 Myocarditis in diseases classified elsewhere
0.000 0.291 0.709
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.291 0.709
I32 Pericarditis in diseases classified elsewhere
0.000 0.291 0.709
K90.9 Intestinal malabsorption, unspecified
0.000 0.291 0.709
M06.34 Rheumatoid nodule (Hand)
0.000 0.291 0.709
E78.4 Other hyperlipidaemia
0.000 0.292 0.708
I15.1 Hypertension secondary to other renal disorders
0.000 0.292 0.708
M45 Ankylosing spondylitis
0.000 0.293 0.707
K74.4 Secondary biliary cirrhosis
0.000 0.294 0.706
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.294 0.706
K74.1 Hepatic sclerosis
0.000 0.294 0.706
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.295 0.705
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.295 0.705
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.295 0.705
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.295 0.705
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.295 0.705
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.295 0.705
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.295 0.705
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.295 0.705
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.295 0.705
H40.4 Glaucoma secondary to eye inflammation
0.000 0.297 0.703
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.298 0.702
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.298 0.701
I12.9 Hypertensive renal disease without renal failure
0.000 0.299 0.701
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.301 0.699
E06.3 Autoimmune thyroiditis
0.000 0.301 0.699
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.302 0.698
K80.3 Calculus of bile duct with cholangitis
0.000 0.302 0.697
K82.3 Fistula of gallbladder
0.000 0.303 0.697
H43.0 Vitreous prolapse
0.000 0.303 0.696
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.304 0.696
H42 Glaucoma in diseases classified elsewhere
0.000 0.304 0.696
H43.1 Vitreous haemorrhage
0.000 0.304 0.695
G30 Alzheimer's disease
0.694 0.305 0.001
M11 Other crystal arthropathies
0.000 0.307 0.693
I21 Acute myocardial infarction
0.000 0.307 0.693
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.309 0.690
E83.8 Other disorders of mineral metabolism
0.683 0.310 0.007
E83.2 Disorders of zinc metabolism
0.683 0.310 0.007
E83.0 Disorders of copper metabolism
0.683 0.310 0.007
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.312 0.688
K73.9 Chronic hepatitis, unspecified
0.000 0.312 0.688
H34.9 Retinal vascular occlusion, unspecified
0.000 0.312 0.688
H34.0 Transient retinal artery occlusion
0.000 0.312 0.688
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.312 0.688
E07.1 Dyshormogenetic goitre
0.000 0.313 0.687
E07.0 Hypersecretion of calcitonin
0.000 0.313 0.687
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.315 0.685
G90-G99 Other disorders of the nervous system
0.682 0.318 0.001
H40.6 Glaucoma secondary to drugs
0.000 0.318 0.682
H40.3 Glaucoma secondary to eye trauma
0.000 0.318 0.682
Q60-Q64 Congenital malformations of the urinary system
0.000 0.320 0.680
E11.8 With unspecified complications
0.000 0.322 0.678
E79 Disorders of purine and pyrimidine metabolism
0.000 0.323 0.677
K51.4 Pseudopolyposis of colon
0.676 0.323 0.000
E84 Cystic fibrosis
0.000 0.323 0.676
I11 Hypertensive heart disease
0.000 0.324 0.676
M75 Shoulder lesions
0.000 0.324 0.676
M12 Other specific arthropathies
0.000 0.326 0.673
K90.8 Other intestinal malabsorption
0.000 0.326 0.673
K72.1 Chronic hepatic failure
0.000 0.327 0.673
H40.5 Glaucoma secondary to other eye disorders
0.000 0.328 0.672
I40 Acute myocarditis
0.000 0.329 0.671
K55-K64 Other diseases of intestines
0.000 0.329 0.671
K51.0 Ulcerative (chronic) enterocolitis
0.670 0.330 0.000
M75.0 Adhesive capsulitis of shoulder
0.000 0.330 0.670
Q61 Cystic kidney disease
0.000 0.332 0.668
I45.2 Bifascicular block
0.000 0.333 0.667
K60 Fissure and fistula of anal and rectal regions
0.000 0.337 0.663
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.338 0.662
K81.8 Other cholecystitis
0.000 0.338 0.662
I31.3 Pericardial effusion (noninflammatory)
0.000 0.339 0.661
M07.6 Other enteropathic arthropathies
0.000 0.340 0.660
M07.5 Arthropathy in ulcerative colitis
0.000 0.340 0.660
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.340 0.660
M07.2 Psoriatic spondylitis
0.000 0.340 0.660
M07.1 Arthritis mutilans
0.000 0.340 0.660
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.340 0.660
E07.8 Other specified disorders of thyroid
0.000 0.341 0.659
J40-J47 Chronic lower respiratory diseases
0.000 0.344 0.656
G30.9 Alzheimer's disease, unspecified
0.655 0.345 0.000
K82.0 Obstruction of gallbladder
0.000 0.345 0.654
G81 Hemiplegia
0.654 0.346 0.000
G83 Other paralytic syndromes
0.652 0.348 0.000
I46.1 Sudden cardiac death, so described
0.000 0.348 0.652
I36 Nonrheumatic tricuspid valve disorders
0.000 0.349 0.651
K60.2 Anal fissure, unspecified
0.000 0.349 0.651
K75.8 Other specified inflammatory liver diseases
0.000 0.350 0.650
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.353 0.646
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.354 0.646
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.354 0.646
Chapter X Diseases of the respiratory system
0.000 0.354 0.646
I15.9 Seconday hypertension, unspecified
0.000 0.356 0.644
K51.1 Ulcerative (chronic) ileocolitis
0.642 0.357 0.000
M86-M90 Other osteopathies
0.000 0.359 0.641
K75.0 Abscess of liver
0.000 0.366 0.634
I45.8 Other specified conduction disorders
0.000 0.368 0.632
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.369 0.631
I22.8 Subsequent myocardial infarction of other sites
0.000 0.370 0.630
G93 Other disorders of brain
0.627 0.373 0.000
I24.1 Dressler's syndrome
0.000 0.373 0.627
M77 Other enthesopathies
0.000 0.375 0.625
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.379 0.621
M07.38 Other psoriatic arthropathies (Other)
0.000 0.380 0.620
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.380 0.620
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.380 0.620
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.380 0.620
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.380 0.620
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.380 0.620
E05.9 Thyrotoxicosis, unspecified
0.000 0.380 0.620
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.381 0.619
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.385 0.615
K75.2 Nonspecific reactive hepatitis
0.000 0.385 0.615
K75.1 Phlebitis of portal vein
0.000 0.385 0.615
I37 Pulmonary valve disorders
0.000 0.385 0.614
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.386 0.614
I45.5 Other specified heart block
0.000 0.388 0.612
E11.4 With neurological complications
0.000 0.388 0.612
H31 Other disorders of choroid
0.000 0.389 0.611
I44 Atrioventricular and left bundle-branch block
0.000 0.390 0.610
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.390 0.610
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.390 0.610
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.390 0.610
K60.0 Acute anal fissure
0.000 0.390 0.610
I51 Complications and ill-defined descriptions of heart disease
0.000 0.391 0.609
M75.2 Bicipital tendinitis
0.000 0.391 0.609
Q61.3 Polycystic kidney, unspecified
0.000 0.392 0.608
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.393 0.607
K50.0 Crohn's disease of small intestine
0.000 0.394 0.606
K50.8 Other Crohn's disease
0.001 0.395 0.605
M00-M03 Infectious arthropathies
0.000 0.395 0.605
Q80-Q89 Other congenital malformations
0.000 0.395 0.605
I15.8 Other secondary hypertension
0.000 0.396 0.604
I15.2 Hypertension secondary to endocrine disorders
0.000 0.396 0.604
I15.0 Renovascular hypertension
0.000 0.396 0.604
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.601 0.397 0.002
E46 Unspecified protein-energy malnutrition
0.000 0.398 0.602
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.398 0.602
Q61.0 Congenital single renal cyst
0.000 0.398 0.602
K82.9 Disease of gallbladder, unspecified
0.000 0.403 0.597
E13.8 With unspecified complications
0.000 0.403 0.597
E13.7 With multiple complications
0.000 0.403 0.597
E13.6 With other specified complications
0.000 0.403 0.597
E13.5 With peripheral circulatory complications
0.000 0.403 0.597
E13.4 With neurological complications
0.000 0.403 0.597
E13.3 With ophthalmic complications
0.000 0.403 0.597
E13.2 With renal complications
0.000 0.403 0.597
E13.1 With ketoacidosis
0.000 0.403 0.597
E13.0 With coma
0.000 0.403 0.597
E89.2 Postprocedural hypoparathyroidism
0.000 0.405 0.595
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.405 0.595
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.405 0.595
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.405 0.595
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.405 0.595
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.405 0.595
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.405 0.595
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.405 0.595
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.405 0.595
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.407 0.593
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.407 0.593
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.409 0.591
M06.38 Rheumatoid nodule (Other)
0.000 0.409 0.591
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.409 0.591
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.409 0.591
M06.33 Rheumatoid nodule (Forearm)
0.000 0.409 0.591
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.409 0.591
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.409 0.591
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.409 0.591
Q50-Q56 Congenital malformations of genital organs
0.000 0.411 0.589
G81.9 Hemiplegia, unspecified
0.589 0.411 0.000
M65.2 Calcific tendinitis
0.000 0.412 0.588
M65.0 Abscess of tendon sheath
0.000 0.412 0.588
G83.4 Cauda equina syndrome
0.588 0.412 0.000
Q61.2 Polycystic kidney, adult type
0.000 0.413 0.587
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.413 0.587
E73 Lactose intolerance
0.000 0.413 0.586
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.586 0.414 0.000
K58 Irritable bowel syndrome
0.000 0.415 0.585
G93.4 Encephalopathy, unspecified
0.584 0.416 0.000
E06.5 Other chronic thyroiditis
0.000 0.417 0.583
E06.4 Drug-induced thyroiditis
0.000 0.417 0.583
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.417 0.583
E06.1 Subacute thyroiditis
0.000 0.417 0.583
E06.0 Acute thyroiditis
0.000 0.417 0.583
K75.9 Inflammatory liver disease, unspecified
0.000 0.417 0.583
I21.9 Acute myocardial infarction, unspecified
0.000 0.417 0.583
H30.9 Chorioretinal inflammation, unspecified
0.000 0.418 0.582
J46 Status asthmaticus
0.000 0.418 0.582
M88 Paget's disease of bone [osteitis deformans]
0.000 0.419 0.581
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.420 0.579
E88.2 Lipomatosis, not elsewhere classified
0.000 0.421 0.578
G93.8 Other specified disorders of brain
0.578 0.422 0.000
I51.8 Other ill-defined heart diseases
0.000 0.422 0.578
M65.1 Other infective (teno)synovitis
0.000 0.423 0.577
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.423 0.577
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.423 0.577
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.423 0.577
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.423 0.577
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.423 0.577
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.423 0.577
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.423 0.577
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.424 0.576
G00-G09 Inflammatory diseases of the central nervous system
0.573 0.425 0.002
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.427 0.573
M77.1 Lateral epicondylitis
0.000 0.428 0.572
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.429 0.571
K74.0 Hepatic fibrosis
0.000 0.429 0.570
K55 Vascular disorders of intestine
0.000 0.431 0.569
M10 Gout
0.000 0.432 0.568
G98 Other disorders of nervous system, not elsewhere classified
0.567 0.433 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.434 0.566
K60.5 Anorectal fistula
0.000 0.435 0.565
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.438 0.562
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.438 0.562
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.438 0.562
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.438 0.562
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.438 0.562
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.438 0.562
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.438 0.562
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.438 0.562
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.438 0.562

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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