TreeWAS – Variant ID: rs34592089

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M75 Shoulder lesions	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
M70-M79 Other soft tissue disorders	1.000	0.000	0.000
M25 Other joint disorders, not elsewhere classified	1.000	0.000	0.000
M15-M19 Arthrosis	1.000	0.000	0.000
M20 Acquired deformities of fingers and toes	0.999	0.001	0.000
M13.9 Arthritis, unspecified	0.999	0.001	0.000
M05-M14 Inflammatory polyarthropathies	0.999	0.001	0.000
M13 Other arthritis	0.999	0.001	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.999	0.001	0.000
M75.1 Rotator cuff syndrome	0.998	0.002	0.000
M19 Other arthrosis	0.996	0.004	0.000
M50-M54 Other dorsopathies	0.994	0.006	0.000
M75.0 Adhesive capsulitis of shoulder	0.991	0.009	0.000
M19.9 Arthrosis, unspecified	0.991	0.009	0.000
M20.4 Other hammer toe(s) (acquired)	0.989	0.011	0.000
M45-M49 Spondylopathies	0.989	0.011	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.989	0.011	0.000
M54 Dorsalgia	0.988	0.012	0.000
M77 Other enthesopathies	0.987	0.013	0.000
I10 Essential (primary) hypertension	0.000	0.015	0.985
M25.7 Osteophyte	0.984	0.016	0.000
M54.5 Low back pain	0.983	0.017	0.000
M75.5 Bursitis of shoulder	0.982	0.018	0.000
M54.56 Low back pain (Lumbar region)	0.980	0.020	0.000
M25.5 Pain in joint	0.976	0.024	0.000
M20.1 Hallux valgus (acquired)	0.973	0.027	0.000
M22 Disorders of patella	0.967	0.033	0.000
M77.1 Lateral epicondylitis	0.964	0.036	0.000
M25.76 Osteophyte (Lower leg)	0.958	0.042	0.000
M17 Gonarthrosis [arthrosis of knee]	0.957	0.043	0.000
M20.3 Other deformity of hallux (acquired)	0.955	0.045	0.000
M17.0 Primary gonarthrosis, bilateral	0.950	0.050	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.948	0.052	0.000
M40-M43 Deforming dorsopathies	0.940	0.060	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.939	0.061	0.000
M86-M90 Other osteopathies	0.934	0.066	0.000
M25.56 Pain in joint (Lower leg)	0.930	0.070	0.000
I10-I15 Hypertensive diseases	0.000	0.079	0.921
F30-F39 Mood [affective] disorders	0.919	0.081	0.000
Chapter V Mental and behavioural disorders	0.918	0.082	0.000
F31 Bipolar affective disorder	0.915	0.085	0.000
M48 Other spondylopathies	0.904	0.096	0.000
M45 Ankylosing spondylitis	0.903	0.097	0.000
# Top node	0.897	0.103	0.000
M25.4 Effusion of joint	0.894	0.106	0.000
M19.94 Arthrosis, unspecified (Hand)	0.889	0.111	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.887	0.113	0.000
M75.3 Calcific tendinitis of shoulder	0.886	0.114	0.000
M75.4 Impingement syndrome of shoulder	0.885	0.115	0.000
M19.0 Primary arthrosis of other joints	0.884	0.116	0.000
M80-M85 Disorders of bone density and structure	0.882	0.118	0.000
F60-F69 Disorders of adult personality and behaviour	0.875	0.125	0.000
I12 Hypertensive renal disease	0.000	0.126	0.874
T36-T50 Poisoning by drugs, medicaments and biological substances	0.873	0.127	0.000
F31.9 Bipolar affective disorder, unspecified	0.872	0.128	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.872	0.128	0.000
M41 Scoliosis	0.864	0.136	0.000
M15 Polyarthrosis	0.862	0.138	0.000
M48.0 Spinal stenosis	0.862	0.138	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.861	0.139	0.000
M25.51 Pain in joint (Shoulder region)	0.861	0.139	0.000
M77.9 Enthesopathy, unspecified	0.858	0.142	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.857	0.143	0.000
Chapter VI Diseases of the nervous system	0.856	0.144	0.000
M25.77 Osteophyte (Ankle and foot)	0.852	0.148	0.000
M25.8 Other specified joint disorders	0.851	0.149	0.000
S60-S69 Injuries to the wrist and hand	0.844	0.156	0.000
F99-F99 Unspecified mental disorder	0.842	0.158	0.000
M47 Spondylosis	0.841	0.159	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.840	0.160	0.000
M22.2 Patellofemoral disorders	0.839	0.161	0.000
M22.4 Chondromalacia patellae	0.838	0.162	0.000
M91-M94 Chondropathies	0.832	0.168	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.174	0.826
M50 Cervical disk disorders	0.826	0.174	0.000
M22.3 Other derangements of patella	0.825	0.175	0.000
F60 Specific personality disorders	0.823	0.177	0.000
M54.9 Dorsalgia, unspecified	0.822	0.178	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.820	0.180	0.000
M89 Other disorders of bone	0.818	0.182	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.816	0.184	0.000
M87 Osteonecrosis	0.815	0.185	0.000
M41.9 Scoliosis, unspecified	0.810	0.190	0.000
M53 Other dorsopathies, not elsewhere classified	0.808	0.192	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.807	0.193	0.000
M24 Other specific joint derangements	0.803	0.197	0.000
Chapter XX External causes of morbidity and mortality	0.801	0.199	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.792	0.208	0.000
M25.9 Joint disorder, unspecified	0.790	0.210	0.000
S64 Injury of nerves at wrist and hand level	0.789	0.211	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.789	0.211	0.000
M40 Kyphosis and lordosis	0.788	0.212	0.000
F99 Mental disorder, not otherwise specified	0.788	0.212	0.000
F33 Recurrent depressive disorder	0.787	0.213	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.787	0.213	0.000
S10-S19 Injuries to the neck	0.786	0.214	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.786	0.214	0.000
M25.46 Effusion of joint (Lower leg)	0.786	0.214	0.000
M25.78 Osteophyte (Other)	0.784	0.216	0.000
M49 Spondylopathies in diseases classified elsewhere	0.783	0.217	0.000
F80-F89 Disorders of psychological development	0.782	0.218	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.782	0.218	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.779	0.221	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.779	0.221	0.000
M07 Psoriatic and enteropathic arthropathies	0.778	0.222	0.000
M47.8 Other spondylosis	0.775	0.225	0.000
M54.8 Other dorsalgia	0.774	0.226	0.000
G20-G26 Extrapyramidal and movement disorders	0.772	0.228	0.000
F30 Manic episode	0.772	0.228	0.000
M25.54 Pain in joint (Hand)	0.772	0.228	0.000
M54.55 Low back pain (Thoracolumbar region)	0.771	0.229	0.000
M46 Other inflammatory spondylopathies	0.767	0.233	0.000
M25.3 Other instability of joint	0.767	0.233	0.000
M65-M68 Disorders of synovium and tendon	0.767	0.233	0.000
M25.58 Pain in joint (Other)	0.767	0.233	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.766	0.234	0.000
M22.0 Recurrent dislocation of patella	0.761	0.239	0.000
C50 Malignant neoplasm of breast	0.761	0.239	0.000
M25.0 Haemarthrosis	0.761	0.239	0.000
M06 Other rheumatoid arthritis	0.761	0.239	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.760	0.240	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.760	0.240	0.000
M25.71 Osteophyte (Shoulder region)	0.757	0.243	0.000
M80 Osteoporosis with pathological fracture	0.756	0.244	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.753	0.247	0.000
F34 Persistent mood [affective] disorders	0.753	0.247	0.000
M77.4 Metatarsalgia	0.753	0.247	0.000
C50-C50 Malignant neoplasm of breast	0.752	0.248	0.000
S40-S49 Injuries to the shoulder and upper arm	0.752	0.248	0.000
M47.82 Other spondylosis (Cervical region)	0.752	0.248	0.000
M54.4 Lumbago with sciatica	0.748	0.252	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.748	0.252	0.000
Chapter II Neoplasms	0.747	0.253	0.000
M25.52 Pain in joint (Upper arm)	0.747	0.253	0.000
C50.4 Upper-outer quadrant of breast	0.746	0.254	0.000
M13.93 Arthritis, unspecified (Forearm)	0.746	0.254	0.000
M16 Coxarthrosis [arthrosis of hip]	0.745	0.255	0.000
V80-V89 Other land transport accidents	0.744	0.255	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.743	0.257	0.000
M87.9 Osteonecrosis, unspecified	0.743	0.257	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.742	0.258	0.000
M54.2 Cervicalgia	0.741	0.258	0.000
M18 Arthrosis of first carpometacarpal joint	0.741	0.259	0.000
M25.84 Other specified joint disorders (Hand)	0.741	0.259	0.000
M19.2 Other secondary arthrosis	0.741	0.259	0.000
S64.4 Injury of digital nerve of other finger	0.741	0.259	0.000
G25 Other extrapyramidal and movement disorders	0.740	0.260	0.000
F60.3 Emotionally unstable personality disorder	0.739	0.261	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.739	0.261	0.000
M54.50 Low back pain (Multiple sites in spine)	0.736	0.264	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.735	0.265	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.735	0.265	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.734	0.266	0.000
C50.8 Overlapping lesion of breast	0.733	0.267	0.000
M48.02 Spinal stenosis (Cervical region)	0.732	0.268	0.000
M86 Osteomyelitis	0.729	0.271	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.727	0.273	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.725	0.275	0.000
F69 Unspecified disorder of adult personality and behaviour	0.724	0.276	0.000
M76 Enthesopathies of lower limb, excluding foot	0.724	0.276	0.000
M48.09 Spinal stenosis (Site unspecified)	0.723	0.277	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.721	0.279	0.000
T21 Burn and corrosion of trunk	0.719	0.281	0.000
T23 Burn and corrosion of wrist and hand	0.718	0.282	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
F60.9 Personality disorder, unspecified	0.717	0.283	0.000
M75.8 Other shoulder lesions	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
M33 Dermatopolymyositis	0.717	0.283	0.000
M32 Systemic lupus erythematosus	0.717	0.283	0.000
M30 Polyarteritis nodosa and related conditions	0.717	0.283	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.717	0.283	0.000
M25.2 Flail joint	0.717	0.283	0.000
M25.1 Fistula of joint	0.717	0.283	0.000
G62 Other polyneuropathies	0.717	0.283	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.717	0.283	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.716	0.284	0.000
M14 Arthropathies in other diseases classified elsewhere	0.716	0.284	0.000
M12 Other specific arthropathies	0.716	0.284	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284	0.000
M08 Juvenile arthritis	0.716	0.284	0.000
M13.8 Other specified arthritis	0.716	0.284	0.000
M13.1 Monoarthritis, not elsewhere classified	0.716	0.284	0.000
M48.06 Spinal stenosis (Lumbar region)	0.716	0.284	0.000
M19.8 Other specified arthrosis	0.714	0.286	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.714	0.286	0.000
M81 Osteoporosis without pathological fracture	0.713	0.287	0.000
M50.3 Other cervical disk degeneration	0.713	0.287	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.710	0.290	0.000
M54.0 Panniculitis affecting regions of neck and back	0.708	0.292	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.708	0.292	0.000
M77.5 Other enthesopathy of foot	0.708	0.292	0.000
M77.3 Calcaneal spur	0.708	0.292	0.000
M77.2 Periarthritis of wrist	0.708	0.292	0.000
M77.0 Medial epicondylitis	0.708	0.292	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.708	0.292	0.000
S61 Open wound of wrist and hand	0.708	0.292	0.000
C50.1 Central portion of breast	0.707	0.293	0.000
M25.79 Osteophyte (Site unspecified)	0.705	0.295	0.000
M25.73 Osteophyte (Forearm)	0.705	0.295	0.000
M25.70 Osteophyte (Multiple sites)	0.705	0.295	0.000
M54.54 Low back pain-Thoracic	0.705	0.295	0.000
M54.53 Low back pain-Cervicothoracic	0.705	0.295	0.000
M54.52 Low back pain-Cervical	0.705	0.295	0.000
M54.51 Low back pain-Occipit-atl-axl	0.705	0.295	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.704	0.296	0.000
M89.8 Other specified disorders of bone	0.704	0.296	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.702	0.298	0.000
S68 Traumatic amputation of wrist and hand	0.702	0.298	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.701	0.299	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.299	0.700
Chapter XXII Codes for special purposes	0.700	0.300	0.000
M25.59 Pain in joint (Site unspecified)	0.698	0.302	0.000
G90-G99 Other disorders of the nervous system	0.694	0.306	0.000
M50.2 Other cervical disk displacement	0.694	0.306	0.000
M22.1 Recurrent subluxation of patella	0.693	0.307	0.000
M22.9 Disorder of patella, unspecified	0.693	0.307	0.000
M17.3 Other posttraumatic gonarthrosis	0.692	0.308	0.000
M60-M63 Disorders of muscles	0.692	0.308	0.000
M77.19 Lateral epicondylitis (Site unspecified)	0.691	0.309	0.000
M77.18 Lateral epicondylitis-Other	0.691	0.309	0.000
M77.17 Lateral epicondylitis-Ankle/Foot	0.691	0.309	0.000
M77.16 Lateral epicondylitis (Lower leg)	0.691	0.309	0.000
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.691	0.309	0.000
M77.14 Lateral epicondylitis-Hand	0.691	0.309	0.000
M77.13 Lateral epicondylitis-Forearm	0.691	0.309	0.000
M77.11 Lateral epicondylitis-Shldr region	0.691	0.309	0.000
M77.10 Lateral epicondylitis (Multiple sites)	0.691	0.309	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.690	0.309	0.000
M90 Osteopathies in diseases classified elsewhere	0.690	0.310	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.690	0.310	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.689	0.311	0.000
I11 Hypertensive heart disease	0.000	0.311	0.689
M22.8 Other disorders of patella	0.688	0.312	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.686	0.313	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.686	0.313	0.000
S61.1 Open wound of finger(s) with damage to nail	0.686	0.314	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.685	0.315	0.000
W50-W64 Exposure to animate mechanical forces	0.684	0.316	0.000
M17.5 Other secondary gonarthrosis	0.682	0.318	0.000
F39 Unspecified mood [affective] disorder	0.681	0.318	0.000
M15.8 Other polyarthrosis	0.681	0.319	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.681	0.319	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.681	0.319	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.680	0.320	0.000
M13.0 Polyarthritis, unspecified	0.680	0.320	0.000
M71 Other bursopathies	0.680	0.320	0.000
M40.2 Other and unspecified kyphosis	0.679	0.321	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.678	0.321	0.000
G25.0 Essential tremor	0.678	0.322	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.677	0.322	0.000
M43 Other deforming dorsopathies	0.677	0.323	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.676	0.324	0.000
M94 Other disorders of cartilage	0.675	0.325	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.675	0.325	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.675	0.325	0.000
M16.7 Other secondary coxarthrosis	0.675	0.325	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.674	0.326	0.000
M42 Spinal osteochondrosis	0.674	0.326	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.674	0.326	0.000
M75.9 Shoulder lesion, unspecified	0.673	0.327	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.673	0.327	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.672	0.328	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.672	0.328	0.000
M15.1 Heberden's nodes (with arthropathy)	0.672	0.328	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.670	0.330	0.000
M54.1 Radiculopathy	0.668	0.332	0.000
M06.0 Seronegative rheumatoid arthritis	0.668	0.332	0.000
M00-M03 Infectious arthropathies	0.667	0.333	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.665	0.335	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.665	0.335	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.664	0.336	0.000
F81 Specific developmental disorders of scholastic skills	0.663	0.336	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.662	0.338	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.661	0.339	0.000
I15 Secondary hypertension	0.000	0.340	0.660
I13 Hypertensive heart and renal disease	0.000	0.340	0.660
M19.02 Primary arthrosis of other joints (Upper arm)	0.660	0.340	0.000
C51-C58 Malignant neoplasms of female genital organs	0.660	0.340	0.000
F38 Other mood [affective] disorders	0.659	0.341	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.659	0.341	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.658	0.342	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.658	0.342	0.000
F70-F79 Mental retardation	0.658	0.342	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.657	0.342	0.000
M25.74 Osteophyte (Hand)	0.657	0.343	0.000
F31.8 Other bipolar affective disorders	0.656	0.344	0.000
F31.7 Bipolar affective disorder, currently in remission	0.656	0.344	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.656	0.344	0.000
M23 Internal derangement of knee	0.656	0.344	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.655	0.345	0.000
X60-X84 Intentional self-harm	0.654	0.346	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.653	0.347	0.000
M89.0 Algoneurodystrophy	0.653	0.347	0.000
M20.0 Deformity of finger(s)	0.652	0.348	0.000
M93 Other osteochondropathies	0.650	0.350	0.000
M24.6 Ankylosis of joint	0.650	0.350	0.000
M11 Other crystal arthropathies	0.649	0.351	0.000
M19.98 Arthrosis, unspecified (Other)	0.649	0.351	0.000
M48.9 Spondylopathy, unspecified	0.648	0.351	0.000
M48.8 Other specified spondylopathies	0.648	0.351	0.000
M48.4 Fatigue fracture of vertebra	0.648	0.351	0.000
M48.3 Traumatic spondylopathy	0.648	0.351	0.000
M48.2 Kissing spine	0.648	0.351	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.648	0.351	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.647	0.352	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.647	0.352	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.647	0.352	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.647	0.352	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.647	0.352	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.647	0.352	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.647	0.352	0.000
M21 Other acquired deformities of limbs	0.647	0.353	0.000
T79-T79 Certain early complications of trauma	0.645	0.354	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.645	0.355	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.645	0.355	0.000
S67 Crushing injury of wrist and hand	0.644	0.356	0.000
G95 Other diseases of spinal cord	0.644	0.356	0.000
F30.9 Manic episode, unspecified	0.643	0.357	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.643	0.357	0.000
T17 Foreign body in respiratory tract	0.642	0.358	0.000
M50.9 Cervical disk disorder, unspecified	0.642	0.358	0.000
F64 Gender identity disorders	0.642	0.358	0.000
S19 Other and unspecified injuries of neck	0.641	0.359	0.000
M25.49 Effusion of joint (Site unspecified)	0.641	0.359	0.000
M25.48 Effusion of joint (Other)	0.641	0.359	0.000
M25.44 Effusion of joint (Hand)	0.641	0.359	0.000
M25.43 Effusion of joint (Forearm)	0.641	0.359	0.000
M25.42 Effusion of joint (Upper arm)	0.641	0.359	0.000
M25.41 Effusion of joint (Shoulder region)	0.641	0.359	0.000
M25.40 Effusion of joint (Multiple sites)	0.641	0.359	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.640	0.360	0.000
M85 Other disorders of bone density and structure	0.640	0.360	0.000
M84 Disorders of continuity of bone	0.639	0.361	0.000
M19.1 Posttraumatic arthrosis of other joints	0.639	0.361	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.639	0.361	0.000
D00-D09 In situ neoplasms	0.639	0.361	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.363	0.637
G24 Dystonia	0.637	0.363	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.636	0.363	0.000
T33-T35 Frostbite	0.636	0.364	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.636	0.364	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.636	0.364	0.000
Chapter IX Diseases of the circulatory system	0.001	0.364	0.634
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.635	0.364	0.000
C56 Malignant neoplasm of ovary	0.635	0.365	0.000
G82 Paraplegia and tetraplegia	0.635	0.365	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.635	0.365	0.000
M19.08 Primary arthrosis of other joints (Other)	0.634	0.366	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.634	0.366	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.634	0.366	0.000
F34.1 Dysthymia	0.634	0.366	0.000
M47.1 Other spondylosis with myelopathy	0.634	0.366	0.000
M54.6 Pain in thoracic spine	0.633	0.366	0.000
G62.9 Polyneuropathy, unspecified	0.633	0.367	0.000
M83 Adult osteomalacia	0.632	0.368	0.000
Y10-Y34 Event of undetermined intent	0.632	0.368	0.000
Q60-Q64 Congenital malformations of the urinary system	0.632	0.368	0.000
M25.72 Osteophyte (Upper arm)	0.631	0.368	0.000
I71 Aortic aneurysm and dissection	0.000	0.369	0.631
Y00-Y09 Assault	0.630	0.370	0.000
S20-S29 Injuries to the thorax	0.629	0.371	0.000
C50.0 Nipple and areola	0.628	0.372	0.000
F68 Other disorders of adult personality and behaviour	0.628	0.372	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.628	0.372	0.000
F65 Disorders of sexual preference	0.628	0.372	0.000
F63 Habit and impulse disorders	0.628	0.372	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.628	0.372	0.000
F61 Mixed and other personality disorders	0.628	0.372	0.000
G25.3 Myoclonus	0.627	0.373	0.000
M25.53 Pain in joint (Forearm)	0.626	0.373	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.626	0.374	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.626	0.374	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.626	0.374	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.626	0.374	0.000
T36 Poisoning by systemic antibiotics	0.626	0.374	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.625	0.375	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.625	0.375	0.000
S14 Injury of nerves and spinal cord at neck level	0.624	0.376	0.000
M47.89 Other spondylosis (Site unspecified)	0.624	0.376	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.624	0.376	0.000
M75.2 Bicipital tendinitis	0.623	0.376	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.622	0.378	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.622	0.378	0.000
W00-W19 Falls	0.621	0.379	0.000
M54.89 Other dorsalgia (Site unspecified)	0.621	0.379	0.000
S69 Other and unspecified injuries of wrist and hand	0.621	0.379	0.000
M07.3 Other psoriatic arthropathies	0.620	0.380	0.000
M82 Osteoporosis in diseases classified elsewhere	0.620	0.380	0.000
S11 Open wound of neck	0.620	0.380	0.000
M41.8 Other forms of scoliosis	0.619	0.380	0.000
M41.5 Other secondary scoliosis	0.619	0.380	0.000
M41.4 Neuromuscular scoliosis	0.619	0.380	0.000
M41.3 Thoracogenic scoliosis	0.619	0.380	0.000
M41.2 Other idiopathic scoliosis	0.619	0.380	0.000
M41.1 Juvenile idiopathic scoliosis	0.619	0.380	0.000
M41.0 Infantile idiopathic scoliosis	0.619	0.380	0.000
V20-V29 Motorcycle rider injured in transport accident	0.619	0.381	0.000
M15.9 Polyarthrosis, unspecified	0.618	0.382	0.000
M15.0 Primary generalised (osteo)arthrosis	0.618	0.382	0.000
M15.4 Erosive (osteo)arthrosis	0.618	0.382	0.000
M15.3 Secondary multiple arthrosis	0.618	0.382	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.618	0.382	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.618	0.382	0.000
M48.04 Spinal stenosis (Thoracic region)	0.618	0.382	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.618	0.382	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.618	0.382	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.618	0.382	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.382	0.618
M25.6 Stiffness of joint, not elsewhere classified	0.617	0.383	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.617	0.383	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.615	0.385	0.000
M77.98 Enthesopathy, unspecified (Other)	0.615	0.385	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.615	0.385	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.615	0.385	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.615	0.385	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.615	0.385	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.615	0.385	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.615	0.385	0.000
M13.94 Arthritis, unspecified (Hand)	0.615	0.385	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.612	0.388	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.612	0.388	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.610	0.390	0.000
M25.88 Other specified joint disorders (Other)	0.610	0.390	0.000
M25.83 Other specified joint disorders (Forearm)	0.610	0.390	0.000
M25.82 Other specified joint disorders (Upper arm)	0.610	0.390	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.610	0.390	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.610	0.390	0.000
M24.1 Other articular cartilage disorders	0.610	0.390	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.610	0.390	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.609	0.391	0.000
I77 Other disorders of arteries and arterioles	0.000	0.391	0.609
X40-X49 Accidental poisoning by and exposure to noxious substances	0.608	0.392	0.000
C50.5 Lower-outer quadrant of breast	0.607	0.393	0.000
V40-V49 Car occupant injured in transport accident	0.607	0.393	0.000
F30.2 Mania with psychotic symptoms	0.607	0.393	0.000
S10 Superficial injury of neck	0.606	0.394	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.605	0.395	0.000
S65 Injury of blood vessels at wrist and hand level	0.605	0.395	0.000
G30-G32 Other degenerative diseases of the nervous system	0.605	0.395	0.000
M81.9 Osteoporosis, unspecified	0.604	0.396	0.000
M88 Paget's disease of bone [osteitis deformans]	0.604	0.396	0.000
T42.1 Iminostilbenes	0.603	0.397	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.603	0.397	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.603	0.397	0.000
T25 Burn and corrosion of ankle and foot	0.603	0.397	0.000
T20 Burn and corrosion of head and neck	0.603	0.397	0.000
M25.31 Other instability of joint (Shoulder region)	0.602	0.398	0.000
S40 Superficial injury of shoulder and upper arm	0.601	0.399	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.601	0.399	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.601	0.399	0.000
F50 Eating disorders	0.600	0.400	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.600	0.400	0.000
M24.0 Loose body in joint	0.600	0.400	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.599	0.400	0.000
M24.5 Contracture of joint	0.599	0.401	0.000
F32 Depressive episode	0.598	0.402	0.000
T40.2 Other opioids	0.597	0.403	0.000
M92 Other juvenile osteochondrosis	0.596	0.404	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.596	0.404	0.000
T00 Superficial injuries involving multiple body regions	0.595	0.405	0.000
M89.88 Other specified disorders of bone (Other)	0.595	0.405	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.594	0.406	0.000
M50.8 Other cervical disk disorders	0.592	0.408	0.000
F20 Schizophrenia	0.591	0.409	0.000
M54.59 Low back pain (Site unspecified)	0.591	0.409	0.000
M13.98 Arthritis, unspecified (Other)	0.590	0.410	0.000
F60.8 Other specific personality disorders	0.590	0.410	0.000
F60.7 Dependent personality disorder	0.590	0.410	0.000
F60.6 Anxious [avoidant] personality disorder	0.590	0.410	0.000
F60.5 Anankastic personality disorder	0.590	0.410	0.000
F60.4 Histrionic personality disorder	0.590	0.410	0.000
F60.2 Dissocial personality disorder	0.590	0.410	0.000
F60.1 Schizoid personality disorder	0.590	0.410	0.000
F60.0 Paranoid personality disorder	0.590	0.410	0.000
M25.06 Haemarthrosis (Lower leg)	0.590	0.410	0.000
G63.2 Diabetic polyneuropathy	0.590	0.410	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.589	0.410	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.589	0.410	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.589	0.410	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.589	0.410	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.589	0.410	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.589	0.410	0.000
G95.2 Cord compression, unspecified	0.588	0.412	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.588	0.412	0.000
T23.2 Burn of second degree of wrist and hand	0.588	0.412	0.000
C81 Hodgkin's disease	0.587	0.413	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.586	0.413	0.000
M89.6 Osteopathy after poliomyelitis	0.586	0.413	0.000
M89.5 Osteolysis	0.586	0.413	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.586	0.413	0.000
M89.3 Hypertrophy of bone	0.586	0.413	0.000
M89.2 Other disorders of bone development and growth	0.586	0.413	0.000
M89.1 Epiphyseal arrest	0.586	0.413	0.000
M31 Other necrotising vasculopathies	0.586	0.414	0.000
M25.34 Other instability of joint (Hand)	0.585	0.415	0.000
F84 Pervasive developmental disorders	0.585	0.415	0.000
M87.8 Other osteonecrosis	0.584	0.416	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations