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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34891485
log Bayes Factor = 9.20547
Chromosome 17   position 40,263,458  (GRCh37) Explore rs34891485 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
0.999 0.001 0.000
I73 Other peripheral vascular diseases
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
I73.9 Peripheral vascular disease, unspecified
0.997 0.003 0.000
I20 Angina pectoris
0.990 0.010 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.989 0.011 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.980 0.020 0.000
I25.1 Atherosclerotic heart disease
0.979 0.021 0.000
Chapter XX External causes of morbidity and mortality
0.977 0.023 0.000
I20.0 Unstable angina
0.972 0.028 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.965 0.035 0.000
E14 Unspecified diabetes mellitus
0.962 0.038 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.952 0.048 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.952 0.048 0.000
I24 Other acute ischaemic heart diseases
0.946 0.054 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.944 0.056 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.941 0.059 0.000
I30-I52 Other forms of heart disease
0.932 0.068 0.000
E14.9 Without complications
0.929 0.071 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.926 0.074 0.000
I72 Other aneurysm
0.924 0.076 0.000
I51 Complications and ill-defined descriptions of heart disease
0.922 0.078 0.000
I71 Aortic aneurysm and dissection
0.922 0.078 0.000
E00-E07 Disorders of thyroid gland
0.920 0.080 0.000
Y40 Systemic antibiotics
0.917 0.083 0.000
I24.8 Other forms of acute ischaemic heart disease
0.915 0.085 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.906 0.094 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.904 0.096 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.893 0.107 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.892 0.108 0.000
E03 Other hypothyroidism
0.890 0.110 0.000
T51 Toxic effect of alcohol
0.889 0.111 0.000
I51.7 Cardiomegaly
0.883 0.117 0.000
I77 Other disorders of arteries and arterioles
0.879 0.121 0.000
E03.9 Hypothyroidism, unspecified
0.873 0.127 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.871 0.129 0.000
I20.1 Angina pectoris with documented spasm
0.869 0.131 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.869 0.131 0.000
L20-L30 Dermatitis and eczema
0.869 0.131 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.867 0.133 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.864 0.136 0.000
E10 Insulin-dependent diabetes mellitus
0.862 0.138 0.000
D60-D64 Aplastic and other anaemias
0.860 0.140 0.000
I20.9 Angina pectoris, unspecified
0.856 0.144 0.000
Chapter V Mental and behavioural disorders
0.853 0.147 0.000
D64 Other anaemias
0.849 0.151 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.848 0.152 0.000
D64.9 Anaemia, unspecified
0.841 0.159 0.000
Chapter VII Diseases of the eye and adnexa
0.836 0.164 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.827 0.173 0.000
I72.8 Aneurysm of other specified arteries
0.826 0.174 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.825 0.175 0.000
E13 Other specified diabetes mellitus
0.824 0.176 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.817 0.183 0.000
E10.9 Without complications
0.816 0.184 0.000
H52 Disorders of refraction and accommodation
0.816 0.184 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.816 0.184 0.000
Y40.9 Systemic antibiotic, unspecified
0.812 0.188 0.000
W20-W49 Exposure to inanimate mechanical forces
0.811 0.189 0.000
E11.3 With ophthalmic complications
0.809 0.191 0.000
X20-X29 Contact with venomous animals and plants
0.805 0.195 0.000
I45 Other conduction disorders
0.803 0.197 0.000
E11.5 With peripheral circulatory complications
0.802 0.198 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.801 0.199 0.000
T51.0 Ethanol
0.801 0.199 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.800 0.200 0.000
H52.1 Myopia
0.800 0.200 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.800 0.200 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.800 0.200 0.000
T93 Sequelae of injuries of lower limb
0.799 0.201 0.000
I70 Atherosclerosis
0.798 0.202 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.797 0.203 0.000
S90-S99 Injuries to the ankle and foot
0.797 0.203 0.000
I51.8 Other ill-defined heart diseases
0.795 0.205 0.000
X60-X84 Intentional self-harm
0.795 0.205 0.000
E11.2 With renal complications
0.792 0.208 0.000
L29 Pruritus
0.790 0.210 0.000
Y40.0 Penicillins
0.787 0.213 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.787 0.213 0.000
I25.3 Aneurysm of heart
0.785 0.215 0.000
S50-S59 Injuries to the elbow and forearm
0.784 0.216 0.000
T56 Toxic effect of metals
0.782 0.218 0.000
S00-S09 Injuries to the head
0.782 0.218 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.782 0.218 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.782 0.218 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.781 0.219 0.000
I23 Certain current complications following acute myocardial infarction
0.777 0.223 0.000
I51.0 Cardiac septal defect, acquired
0.775 0.225 0.000
I34 Nonrheumatic mitral valve disorders
0.773 0.227 0.000
I31 Other diseases of pericardium
0.773 0.227 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.772 0.228 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.771 0.229 0.000
W75-W84 Other accidental threats to breathing
0.771 0.229 0.000
T63 Toxic effect of contact with venomous animals
0.771 0.229 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.768 0.232 0.000
F60-F69 Disorders of adult personality and behaviour
0.768 0.232 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.767 0.233 0.000
Y44 Agents primarily affecting blood constituents
0.767 0.233 0.000
I45.1 Other and unspecified right bundle-branch block
0.767 0.233 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.766 0.234 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.764 0.236 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.764 0.236 0.000
T42.4 Benzodiazepines
0.764 0.236 0.000
Y00-Y09 Assault
0.764 0.236 0.000
I72.3 Aneurysm of iliac artery
0.762 0.238 0.000
I74 Arterial embolism and thrombosis
0.760 0.240 0.000
T40.4 Other synthetic narcotics
0.758 0.242 0.000
T59 Toxic effect of other gases, fumes and vapours
0.756 0.244 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.756 0.244 0.000
I72.0 Aneurysm of carotid artery
0.755 0.245 0.000
T46.1 Calcium-channel blockers
0.750 0.250 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.750 0.250 0.000
T79-T79 Certain early complications of trauma
0.750 0.250 0.000
T45.5 Anticoagulants
0.750 0.250 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.745 0.254 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.745 0.254 0.000
I37 Pulmonary valve disorders
0.745 0.255 0.000
I25.4 Coronary artery aneurysm
0.742 0.258 0.000
E14.3 With ophthalmic complications
0.742 0.258 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.741 0.259 0.000
I77.1 Stricture of artery
0.741 0.259 0.000
I25.5 Ischaemic cardiomyopathy
0.741 0.259 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.740 0.259 0.000
S31 Open wound of abdomen, lower back and pelvis
0.736 0.264 0.000
S30.0 Contusion of lower back and pelvis
0.736 0.264 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.734 0.266 0.000
T51.9 Alcohol, unspecified
0.733 0.267 0.000
X50-X57 Overexertion, travel and privation
0.733 0.267 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.730 0.270 0.000
T43.2 Other and unspecified antidepressants
0.730 0.270 0.000
L27 Dermatitis due to substances taken internally
0.730 0.270 0.000
I46 Cardiac arrest
0.729 0.271 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.728 0.272 0.000
T66-T78 Other and unspecified effects of external causes
0.728 0.272 0.000
I77.8 Other specified disorders of arteries and arterioles
0.727 0.273 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.727 0.273 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.726 0.274 0.000
W50-W64 Exposure to animate mechanical forces
0.725 0.275 0.000
Y40.8 Other systemic antibiotics
0.724 0.276 0.000
S02 Fracture of skull and facial bones
0.719 0.281 0.000
I36 Nonrheumatic tricuspid valve disorders
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
T98 Sequelae of other and unspecified effects of external causes
0.716 0.284 0.000
I73.8 Other specified peripheral vascular diseases
0.716 0.284 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.715 0.284 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.714 0.286 0.000
T58 Toxic effect of carbon monoxide
0.714 0.286 0.000
F43 Reaction to severe stress, and adjustment disorders
0.712 0.288 0.000
E20-E35 Disorders of other endocrine glands
0.712 0.288 0.000
I51.4 Myocarditis, unspecified
0.711 0.289 0.000
L29.2 Pruritus vulvae
0.710 0.290 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.709 0.291 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.709 0.291 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.709 0.291 0.000
T42.3 Barbiturates
0.709 0.291 0.000
T42.2 Succinimides and oxazolidinediones
0.709 0.291 0.000
T42.1 Iminostilbenes
0.709 0.291 0.000
T42.0 Hydantoin derivatives
0.709 0.291 0.000
T92 Sequelae of injuries of upper limb
0.708 0.292 0.000
F60 Specific personality disorders
0.708 0.292 0.000
S06 Intracranial injury
0.706 0.294 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.703 0.296 0.000
T90 Sequelae of injuries of head
0.702 0.298 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.702 0.298 0.000
Y57 Other and unspecified drugs and medicaments
0.702 0.298 0.000
H52.2 Astigmatism
0.701 0.299 0.000
V80-V89 Other land transport accidents
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.701 0.299 0.000
Y10-Y34 Event of undetermined intent
0.701 0.299 0.000
X85-X99 Assault
0.701 0.299 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.701 0.299 0.000
X30-X39 Exposure to forces of nature
0.701 0.299 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
X00-X09 Exposure to smoke, fire and flames
0.701 0.299 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W65-W74 Accidental drowning and submersion
0.701 0.299 0.000
V98-V99 Other and unspecified transport accidents
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.701 0.299 0.000
V90-V94 Water transport accidents
0.701 0.299 0.000
V70-V79 Bus occupant injured in transport accident
0.701 0.299 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.701 0.299 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.701 0.299 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.701 0.299 0.000
V01-V09 Pedestrian injured in transport accident
0.701 0.299 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.700 0.300 0.000
E13.9 Without complications
0.697 0.303 0.000
H49 Paralytic strabismus
0.697 0.303 0.000
I71.0 Dissection of aorta [any part]
0.695 0.305 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.694 0.306 0.000
H52.7 Disorder of refraction, unspecified
0.694 0.306 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.692 0.308 0.000
T65 Toxic effect of other and unspecified substances
0.692 0.308 0.000
T62 Toxic effect of other noxious substances eaten as food
0.692 0.308 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.692 0.308 0.000
T60 Toxic effect of pesticides
0.692 0.308 0.000
T57 Toxic effect of other inorganic substances
0.692 0.308 0.000
T54 Toxic effect of corrosive substances
0.692 0.308 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.692 0.308 0.000
T52 Toxic effect of organic solvents
0.692 0.308 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.692 0.308 0.000
T55 Toxic effect of soaps and detergents
0.692 0.308 0.000
I73.0 Raynaud's syndrome
0.691 0.309 0.000
L10-L14 Bullous disorders
0.690 0.310 0.000
E14.8 With unspecified complications
0.690 0.310 0.000
E14.7 With multiple complications
0.690 0.310 0.000
E14.6 With other specified complications
0.690 0.310 0.000
E14.5 With peripheral circulatory complications
0.690 0.310 0.000
E14.4 With neurological complications
0.690 0.310 0.000
E14.2 Withrenal complications
0.690 0.310 0.000
E14.1 With ketoacidosis
0.690 0.310 0.000
E14.0 With coma
0.690 0.310 0.000
W25 Contact with sharp glass
0.689 0.310 0.000
I30 Acute pericarditis
0.689 0.311 0.000
V20-V29 Motorcycle rider injured in transport accident
0.688 0.312 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.687 0.313 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.686 0.314 0.000
E10.0 With coma
0.685 0.315 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.683 0.317 0.000
Y59 Other and unspecified vaccines and biological substances
0.682 0.317 0.000
Y58 Bacterial vaccines
0.682 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.682 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.682 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.682 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.682 0.317 0.000
I77.6 Arteritis, unspecified
0.682 0.318 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.682 0.318 0.000
S32 Fracture of lumbar spine and pelvis
0.681 0.319 0.000
X23 Contact with hornets, wasps and bees
0.681 0.319 0.000
E06 Thyroiditis
0.681 0.319 0.000
I24.1 Dressler's syndrome
0.678 0.322 0.000
Q50-Q56 Congenital malformations of genital organs
0.678 0.322 0.000
T43.9 Psychotropic drug, unspecified
0.677 0.323 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
T43.6 Psychostimulants with abuse potential
0.677 0.323 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.677 0.323 0.000
V10-V19 Pedal cyclist injured in transport accident
0.676 0.324 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.675 0.325 0.000
S37 Injury of urinary and pelvic organs
0.675 0.325 0.000
S36 Injury of intra-abdominal organs
0.675 0.325 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.675 0.325 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.675 0.325 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.675 0.325 0.000
S91 Open wound of ankle and foot
0.674 0.326 0.000
E07 Other disorders of thyroid
0.671 0.329 0.000
I47 Paroxysmal tachycardia
0.670 0.330 0.000
T91 Sequelae of injuries of neck and trunk
0.669 0.330 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.669 0.331 0.000
I52 Other heart disorders in diseases classified elsewhere
0.668 0.331 0.000
I48 Atrial fibrillation and flutter
0.668 0.331 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.668 0.331 0.000
I41 Myocarditis in diseases classified elsewhere
0.668 0.331 0.000
I40 Acute myocarditis
0.668 0.331 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.668 0.331 0.000
I32 Pericarditis in diseases classified elsewhere
0.668 0.331 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.667 0.333 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.667 0.333 0.000
S80-S89 Injuries to the knee and lower leg
0.666 0.334 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.665 0.335 0.000
F44 Dissociative [conversion] disorders
0.664 0.336 0.000
T95 Sequelae of burns, corrosions and frostbite
0.664 0.336 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.664 0.336 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.664 0.336 0.000
L28 Lichen simplex chronicus and prurigo
0.664 0.336 0.000
Q18 Other congenital malformations of face and neck
0.663 0.337 0.000
I72.9 Aneurysm of unspecified site
0.663 0.337 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.663 0.337 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.663 0.337 0.000
I72.2 Aneurysm of renal artery
0.663 0.337 0.000
I72.1 Aneurysm of artery of upper extremity
0.663 0.337 0.000
V40-V49 Car occupant injured in transport accident
0.662 0.338 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.661 0.338 0.000
E40-E46 Malnutrition
0.661 0.338 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.661 0.338 0.000
I51.6 Cardiovascular disease, unspecified
0.661 0.339 0.000
I51.5 Myocardial degeneration
0.661 0.339 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.661 0.339 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.661 0.339 0.000
L23 Allergic contact dermatitis
0.661 0.339 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.661 0.339 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.661 0.339 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.661 0.339 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.661 0.339 0.000
I31.3 Pericardial effusion (noninflammatory)
0.660 0.340 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.660 0.340 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.660 0.340 0.000
E00 Congenital iodine-deficiency syndrome
0.660 0.340 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.660 0.340 0.000
L30 Other dermatitis
0.660 0.340 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.660 0.340 0.000
E11.6 With other specified complications
0.659 0.340 0.000
E11.0 With coma
0.659 0.340 0.000
S92 Fracture of foot, except ankle
0.659 0.341 0.000
L29.9 Pruritus, unspecified
0.658 0.342 0.000
Y40.7 Antifungal antibiotics, systemically used
0.657 0.343 0.000
Y40.6 Rifamycins
0.657 0.343 0.000
Y40.5 Aminoglycosides
0.657 0.343 0.000
Y40.4 Tetracyclines
0.657 0.343 0.000
Y40.2 Chloramphenicol group
0.657 0.343 0.000
Y40.3 Macrolides
0.657 0.343 0.000
F30-F39 Mood [affective] disorders
0.657 0.343 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.657 0.343 0.000
E10.8 With unspecified complications
0.655 0.345 0.000
T40.2 Other opioids
0.655 0.345 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.655 0.345 0.000
Y54.5 Other diuretics
0.655 0.345 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.654 0.346 0.000
T38.1 Thyroid hormones and substitutes
0.654 0.346 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.652 0.348 0.000
D55-D59 Haemolytic anaemias
0.652 0.348 0.000
I25.2 Old myocardial infarction
0.652 0.348 0.000
H18 Other disorders of cornea
0.652 0.348 0.000
T56.8 Other metals
0.651 0.348 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.650 0.349 0.000
I22 Subsequent myocardial infarction
0.650 0.350 0.000
S50 Superficial injury of forearm
0.650 0.350 0.000
H16 Keratitis
0.649 0.351 0.000
T11 Other injuries of upper limb, level unspecified
0.648 0.352 0.000
Q00-Q07 Congenital malformations of the nervous system
0.646 0.354 0.000
L60-L75 Disorders of skin appendages
0.645 0.355 0.000
F60.9 Personality disorder, unspecified
0.644 0.356 0.000
S70-S79 Injuries to the hip and thigh
0.643 0.357 0.000
T45.0 Antiallergic and antiemetic drugs
0.643 0.357 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.642 0.358 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.640 0.360 0.000
Q35-Q37 Cleft lip and cleft palate
0.640 0.360 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.640 0.360 0.000
L40-L45 Papulosquamous disorders
0.640 0.360 0.000
T50.8 Diagnostic agents
0.640 0.360 0.000
T50.7 Analeptics and opioid receptor antagonists
0.640 0.360 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.640 0.360 0.000
T50.5 Appetite depressants
0.640 0.360 0.000
T50.4 Drugs affecting uric acid metabolism
0.640 0.360 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.640 0.360 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.640 0.360 0.000
T50.1 Loop [high-ceiling] diuretics
0.640 0.360 0.000
T50.0 Mineralocorticoids and their antagonists
0.640 0.360 0.000
E11.1 With ketoacidosis
0.639 0.361 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.639 0.361 0.000
E03.5 Myxoedema coma
0.638 0.362 0.000
E03.4 Atrophy of thyroid (acquired)
0.638 0.362 0.000
E03.3 Postinfectious hypothyroidism
0.638 0.362 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.638 0.362 0.000
E03.1 Congenital hypothyroidism without goitre
0.638 0.362 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.638 0.362 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.638 0.362 0.000
T51.8 Other alcohols
0.637 0.363 0.000
T51.3 Fusel oil
0.637 0.363 0.000
T51.2 2-Propanol
0.637 0.363 0.000
T51.1 Methanol
0.637 0.363 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.636 0.364 0.000
Y44.2 Anticoagulants
0.634 0.366 0.000
W00-W19 Falls
0.634 0.366 0.000
I45.9 Conduction disorder, unspecified
0.634 0.366 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.633 0.367 0.000
S10-S19 Injuries to the neck
0.632 0.368 0.000
T63.4 Venom of other arthropods
0.632 0.368 0.000
D80-D89 Certain disorders involving the immune mechanism
0.631 0.369 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.630 0.370 0.000
I77.5 Necrosis of artery
0.630 0.370 0.000
I77.4 Coeliac artery compression syndrome
0.630 0.370 0.000
I77.3 Arterial fibromuscular dysplasia
0.630 0.370 0.000
I77.2 Rupture of artery
0.630 0.370 0.000
I77.0 Arteriovenous fistula, acquired
0.630 0.370 0.000
Y52 Agents primarily affecting the cardiovascular system
0.626 0.374 0.000
I05-I09 Chronic rheumatic heart diseases
0.626 0.374 0.000
I42 Cardiomyopathy
0.625 0.375 0.000
I46.0 Cardiac arrest with successful resuscitation
0.625 0.375 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.624 0.376 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.624 0.376 0.000
T45.8 Other primarily systemic and haematological agents
0.624 0.376 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.624 0.376 0.000
T45.6 Fibrinolysis-affecting drugs
0.624 0.376 0.000
T45.4 Iron and its compounds
0.624 0.376 0.000
T45.3 Enzymes, not elsewhere classified
0.624 0.376 0.000
T45.2 Vitamins, not elsewhere classified
0.624 0.376 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.624 0.376 0.000
Q60-Q64 Congenital malformations of the urinary system
0.624 0.376 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.623 0.377 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.623 0.377 0.000
T46.7 Peripheral vasodilators
0.623 0.377 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.623 0.377 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.623 0.377 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.623 0.377 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.623 0.377 0.000
W84 Unspecified threat to breathing
0.623 0.377 0.000
L25 Unspecified contact dermatitis
0.623 0.377 0.000
L24 Irritant contact dermatitis
0.623 0.377 0.000
L21 Seborrhoeic dermatitis
0.623 0.377 0.000
L20 Atopic dermatitis
0.623 0.377 0.000
L26 Exfoliative dermatitis
0.623 0.377 0.000
L22 Diaper [napkin] dermatitis
0.623 0.377 0.000
S02.6 Fracture of mandible
0.623 0.377 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.622 0.378 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.622 0.378 0.000
T40.8 Lysergide [LSD]
0.622 0.378 0.000
T40.7 Cannabis (derivatives)
0.622 0.378 0.000
T40.6 Other and unspecified narcotics
0.622 0.378 0.000
T40.5 Cocaine
0.622 0.378 0.000
T40.3 Methadone
0.622 0.378 0.000
T40.1 Heroin
0.622 0.378 0.000
T40.0 Opium
0.622 0.378 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.622 0.378 0.000
L50-L54 Urticaria and erythema
0.619 0.381 0.000
F43.1 Posttraumatic stress disorder
0.619 0.381 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.618 0.382 0.000
E10.7 With multiple complications
0.618 0.382 0.000
E10.6 With other specified complications
0.618 0.382 0.000
I23.8 Other current complications following acute myocardial infarction
0.617 0.383 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.617 0.383 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.615 0.385 0.000
I33 Acute and subacute endocarditis
0.614 0.386 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.612 0.388 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.611 0.389 0.000
F70-F79 Mental retardation
0.611 0.389 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.611 0.389 0.000
I37.1 Pulmonary valve insufficiency
0.610 0.390 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.610 0.390 0.000
F80-F89 Disorders of psychological development
0.609 0.391 0.000
F43.2 Adjustment disorders
0.609 0.391 0.000
D64.8 Other specified anaemias
0.609 0.391 0.000
D64.4 Congenital dyserythropoietic anaemia
0.609 0.391 0.000
D64.3 Other sideroblastic anaemias
0.609 0.391 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.609 0.391 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.609 0.391 0.000
D64.0 Hereditary sideroblastic anaemia
0.609 0.391 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.608 0.392 0.000
S30.2 Contusion of external genital organs
0.608 0.392 0.000
Q80-Q89 Other congenital malformations
0.607 0.393 0.000
T59.8 Other specified gases, fumes and vapours
0.606 0.394 0.000
H49.1 Fourth [trochlear] nerve palsy
0.605 0.395 0.000
Q21 Congenital malformations of cardiac septa
0.603 0.397 0.000
D73 Diseases of spleen
0.603 0.397 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.603 0.397 0.000
W25.9 Unspecified place
0.602 0.398 0.000
H52.3 Anisometropia and aniseikonia
0.602 0.398 0.000
I74.5 Embolism and thrombosis of iliac artery
0.602 0.398 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.601 0.399 0.000
E23 Hypofunction and other disorders of pituitary gland
0.601 0.399 0.000
I45.4 Nonspecific intraventricular block
0.600 0.400 0.000
D50-D53 Nutritional anaemias
0.599 0.401 0.000
Q23 Congenital malformations of aortic and mitral valves
0.598 0.402 0.000
I99 Other and unspecified disorders of circulatory system
0.598 0.402 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.597 0.403 0.000
Q27 Other congenital malformations of peripheral vascular system
0.595 0.405 0.000
Q12 Congenital lens malformations
0.595 0.405 0.000
S56 Injury of muscle and tendon at forearm level
0.595 0.405 0.000
W44 Foreign body entering into or through eye or natural orifice
0.594 0.406 0.000
W21 Striking against or struck by sports equipment
0.594 0.406 0.000
X78 Intentional self-harm by sharp object
0.592 0.408 0.000
I34.0 Mitral (valve) insufficiency
0.592 0.408 0.000
H51 Other disorders of binocular movement
0.592 0.408 0.000
E29 Testicular dysfunction
0.591 0.409 0.000
E13.8 With unspecified complications
0.590 0.409 0.000
E13.7 With multiple complications
0.590 0.409 0.000
E13.6 With other specified complications
0.590 0.409 0.000
E13.5 With peripheral circulatory complications
0.590 0.409 0.000
E13.4 With neurological complications
0.590 0.409 0.000
E13.3 With ophthalmic complications
0.590 0.409 0.000
E13.2 With renal complications
0.590 0.409 0.000
E13.1 With ketoacidosis
0.590 0.409 0.000
E13.0 With coma
0.590 0.409 0.000
Y00 Assault by blunt object
0.590 0.410 0.000
T94.1 Sequelae of injuries, not specified by body region
0.590 0.410 0.000
S31.0 Open wound of lower back and pelvis
0.589 0.411 0.000
Y43 Primarily systemic agents
0.588 0.412 0.000
T14 Injury of unspecified body region
0.588 0.412 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.587 0.413 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.585 0.415 0.000
T90.8 Sequelae of other specified injuries of head
0.585 0.415 0.000
H52.6 Other disorders of refraction
0.585 0.415 0.000
H52.5 Disorders of accommodation
0.585 0.415 0.000
H52.4 Presbyopia
0.585 0.415 0.000
S40-S49 Injuries to the shoulder and upper arm
0.584 0.416 0.000
W46 Contact with hypodermic needle
0.582 0.418 0.000
W45 Foreign body or object entering through skin
0.582 0.418 0.000
W43 Exposure to vibration
0.582 0.418 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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