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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35303200
log Bayes Factor = 18.3789
Chromosome 9   position 82,740,305  (GRCh37) Explore rs35303200 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter II Neoplasms
0.998 0.002 0.000
E00-E07 Disorders of thyroid gland
0.994 0.006 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.994 0.006 0.000
E03 Other hypothyroidism
0.991 0.009 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.991 0.009 0.000
E03.9 Hypothyroidism, unspecified
0.989 0.011 0.000
Chapter I Certain infectious and parasitic diseases
0.988 0.012 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.984 0.016 0.000
S00-S09 Injuries to the head
0.981 0.019 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.980 0.020 0.000
B95-B98 Bacterial, viral and other infectious agents
0.978 0.022 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.978 0.022 0.000
R11 Nausea and vomiting
0.974 0.026 0.000
Chapter XX External causes of morbidity and mortality
0.971 0.029 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.966 0.034 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.960 0.040 0.000
O60-O75 Complications of labour and delivery
0.960 0.040 0.000
C15-C26 Malignant neoplasms of digestive organs
0.958 0.042 0.000
S00 Superficial injury of head
0.957 0.043 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.956 0.044 0.000
M70-M79 Other soft tissue disorders
0.956 0.044 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.955 0.045 0.000
E10-E14 Diabetes mellitus
0.947 0.053 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.943 0.057 0.000
Chapter VI Diseases of the nervous system
0.939 0.061 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.939 0.061 0.000
Z86 Personal history of certain other diseases
0.935 0.065 0.000
Z86.4 Personal history of psychoactive substance abuse
0.930 0.070 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.929 0.071 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.923 0.077 0.000
M79.6 Pain in limb
0.922 0.078 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.919 0.081 0.000
Z60 Problems related to social environment
0.918 0.082 0.000
E11 Non-insulin-dependent diabetes mellitus
0.915 0.085 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.915 0.085 0.000
M20-M25 Other joint disorders
0.914 0.086 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.913 0.087 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.899 0.101 0.000
E70-E90 Metabolic disorders
0.895 0.105 0.000
Chapter IX Diseases of the circulatory system
0.894 0.106 0.000
Z60.2 Living alone
0.891 0.109 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.891 0.109 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.890 0.110 0.000
M45-M49 Spondylopathies
0.889 0.111 0.000
Z34 Supervision of normal pregnancy
0.885 0.115 0.000
C16 Malignant neoplasm of stomach
0.879 0.121 0.000
C20 Malignant neoplasm of rectum
0.878 0.122 0.000
L40-L45 Papulosquamous disorders
0.877 0.123 0.000
C79 Secondary malignant neoplasm of other sites
0.876 0.124 0.000
C78.7 Secondary malignant neoplasm of liver
0.876 0.124 0.000
E11.9 Without complications
0.875 0.125 0.000
S06 Intracranial injury
0.874 0.126 0.000
R42 Dizziness and giddiness
0.873 0.127 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.870 0.130 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.869 0.131 0.000
G20-G26 Extrapyramidal and movement disorders
0.867 0.133 0.000
Z36 Antenatal screening
0.863 0.137 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.862 0.138 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.860 0.140 0.000
E65-E68 Obesity and other hyperalimentation
0.858 0.142 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.858 0.142 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.857 0.143 0.000
Chapter XXII Codes for special purposes
0.854 0.146 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.850 0.150 0.000
O70 Perineal laceration during delivery
0.849 0.151 0.000
C64-C68 Malignant neoplasms of urinary tract
0.848 0.152 0.000
Z35 Supervision of high-risk pregnancy
0.847 0.153 0.000
M50-M54 Other dorsopathies
0.846 0.154 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.845 0.155 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.845 0.155 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.843 0.157 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.841 0.159 0.000
S00.1 Contusion of eyelid and periocular area
0.841 0.159 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.839 0.161 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.838 0.162 0.000
M23 Internal derangement of knee
0.836 0.164 0.000
C80 Malignant neoplasm without specification of site
0.832 0.168 0.000
R14 Flatulence and related conditions
0.828 0.172 0.000
S80-S89 Injuries to the knee and lower leg
0.825 0.175 0.000
O80-O84 Delivery
0.824 0.176 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.823 0.177 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.822 0.178 0.000
Z33 Pregnant state, incidental
0.822 0.178 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.822 0.178 0.000
L08 Other local infections of skin and subcutaneous tissue
0.820 0.180 0.000
Z37 Outcome of delivery
0.818 0.182 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.817 0.183 0.000
G20 Parkinson's disease
0.816 0.184 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.816 0.184 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.815 0.185 0.000
B07 Viral warts
0.814 0.186 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.814 0.186 0.000
S70-S79 Injuries to the hip and thigh
0.814 0.186 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.814 0.186 0.000
Z95.1 Presence of aortocoronary bypass graft
0.813 0.187 0.000
M86-M90 Other osteopathies
0.812 0.188 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.812 0.188 0.000
S00.8 Superficial injury of other parts of head
0.811 0.189 0.000
R19.5 Other fecal abnormalities
0.809 0.191 0.000
L40 Psoriasis
0.806 0.194 0.000
O70.1 Second degree perineal laceration during delivery
0.804 0.196 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.803 0.197 0.000
S00.0 Superficial injury of scalp
0.802 0.198 0.000
W00-W19 Falls
0.802 0.198 0.000
S60-S69 Injuries to the wrist and hand
0.800 0.200 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.798 0.201 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.797 0.203 0.000
M79.63 Pain in limb (Forearm)
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.797 0.203 0.000
Chapter V Mental and behavioural disorders
0.795 0.205 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.794 0.206 0.000
I74 Arterial embolism and thrombosis
0.791 0.209 0.000
M79.69 Pain in limb (Site unspecified)
0.790 0.210 0.000
E20-E35 Disorders of other endocrine glands
0.789 0.211 0.000
I73 Other peripheral vascular diseases
0.789 0.211 0.000
S20-S29 Injuries to the thorax
0.789 0.211 0.000
M65-M68 Disorders of synovium and tendon
0.788 0.211 0.000
C16.9 Stomach, unspecified
0.785 0.215 0.000
Chapter VII Diseases of the eye and adnexa
0.784 0.216 0.000
S00.3 Superficial injury of nose
0.783 0.217 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.783 0.217 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.782 0.218 0.000
W20-W49 Exposure to inanimate mechanical forces
0.781 0.219 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.781 0.219 0.000
Z13 Special screening examination for other diseases and disorders
0.780 0.220 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.780 0.220 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.779 0.221 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.778 0.222 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.778 0.222 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.776 0.224 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.776 0.224 0.000
M79.67 Pain in limb (Ankle and foot)
0.775 0.225 0.000
M79.66 Pain in limb (Lower leg)
0.774 0.226 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.771 0.229 0.000
M05-M14 Inflammatory polyarthropathies
0.770 0.230 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.769 0.231 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.768 0.232 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.768 0.232 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.768 0.232 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.768 0.232 0.000
O85-O92 Complications predominantly related to the puerperium
0.767 0.233 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.766 0.234 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.766 0.234 0.000
O63 Long labour
0.765 0.234 0.000
L03 Cellulitis
0.763 0.237 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.763 0.237 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.761 0.239 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.761 0.239 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.761 0.239 0.000
O16 Unspecified maternal hypertension
0.760 0.240 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.757 0.243 0.000
S00.9 Superficial injury of head, part unspecified
0.757 0.243 0.000
E66 Obesity
0.756 0.244 0.000
R18 Ascites
0.755 0.245 0.000
R26 Abnormalities of gait and mobility
0.755 0.245 0.000
Z88.0 Personal history of allergy to penicillin
0.754 0.246 0.000
R47-R49 Symptoms and signs involving speech and voice
0.753 0.247 0.000
M48 Other spondylopathies
0.752 0.248 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.752 0.248 0.000
R50-R69 General symptoms and signs
0.750 0.250 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.750 0.250 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.750 0.250 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.749 0.251 0.000
I73.9 Peripheral vascular disease, unspecified
0.748 0.252 0.000
M79.8 Other specified soft tissue disorders
0.748 0.252 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.747 0.253 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.747 0.253 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.745 0.255 0.000
B25-B34 Other viral diseases
0.745 0.255 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.745 0.255 0.000
R40 Somnolence, stupor and coma
0.744 0.256 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.743 0.256 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.743 0.257 0.000
Y43 Primarily systemic agents
0.743 0.257 0.000
Z36.8 Other antenatal screening
0.742 0.258 0.000
M35 Other systemic involvement of connective tissue
0.741 0.258 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.740 0.260 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.740 0.260 0.000
Z89 Acquired absence of limb
0.740 0.260 0.000
Z83 Family history of other specific disorders
0.739 0.261 0.000
C18 Malignant neoplasm of colon
0.738 0.262 0.000
O73 Retained placenta and membranes, without haemorrhage
0.738 0.262 0.000
M47 Spondylosis
0.738 0.262 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.737 0.262 0.000
O47 False labour
0.737 0.263 0.000
M79.7 Fibromyalgia
0.737 0.263 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.736 0.264 0.000
V10-V19 Pedal cyclist injured in transport accident
0.735 0.265 0.000
C34 Malignant neoplasm of bronchus and lung
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
Z63 Other problems related to primary support group, including family circumstances
0.734 0.266 0.000
L50-L54 Urticaria and erythema
0.732 0.268 0.000
C16.0 Cardia
0.732 0.268 0.000
C78.2 Secondary malignant neoplasm of pleura
0.732 0.268 0.000
M25 Other joint disorders, not elsewhere classified
0.731 0.269 0.000
L40.5 Arthropathic psoriasis
0.731 0.269 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.730 0.269 0.000
R12 Heartburn
0.728 0.272 0.000
Z72 Problems related to lifestyle
0.728 0.272 0.000
Z76 Persons encountering health services in other circumstances
0.727 0.273 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.727 0.273 0.000
E11.2 With renal complications
0.727 0.273 0.000
I20-I25 Ischaemic heart diseases
0.727 0.273 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.727 0.273 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.727 0.273 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.726 0.274 0.000
E11.4 With neurological complications
0.726 0.274 0.000
S01 Open wound of head
0.726 0.274 0.000
I60-I69 Cerebrovascular diseases
0.726 0.274 0.000
C78.0 Secondary malignant neoplasm of lung
0.725 0.275 0.000
L89 Decubitus ulcer
0.723 0.277 0.000
Z87 Personal history of other diseases and conditions
0.722 0.278 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.721 0.279 0.000
C80.9 Malignant neoplasm, unspecified
0.719 0.281 0.000
G30-G32 Other degenerative diseases of the nervous system
0.719 0.281 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
M72 Fibroblastic disorders
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S90-S99 Injuries to the ankle and foot
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
A30-A49 Other bacterial diseases
0.716 0.284 0.000
M79.0 Rheumatism, unspecified
0.715 0.284 0.000
M91-M94 Chondropathies
0.715 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.715 0.285 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.714 0.286 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.714 0.286 0.000
E14 Unspecified diabetes mellitus
0.713 0.287 0.000
E06 Thyroiditis
0.713 0.287 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.713 0.287 0.000
E00 Congenital iodine-deficiency syndrome
0.713 0.287 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.713 0.287 0.000
Z97 Presence of other devices
0.712 0.288 0.000
M80-M85 Disorders of bone density and structure
0.711 0.289 0.000
Z94 Transplanted organ and tissue status
0.711 0.289 0.000
Z35.5 Supervision of elderly primigravida
0.711 0.289 0.000
E03.8 Other specified hypothyroidism
0.711 0.289 0.000
E03.5 Myxoedema coma
0.711 0.289 0.000
E03.4 Atrophy of thyroid (acquired)
0.711 0.289 0.000
E03.3 Postinfectious hypothyroidism
0.711 0.289 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.711 0.289 0.000
E03.1 Congenital hypothyroidism without goitre
0.711 0.289 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.711 0.289 0.000
R45 Symptoms and signs involving emotional state
0.710 0.289 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.710 0.290 0.000
L91 Hypertrophic disorders of skin
0.710 0.290 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.710 0.290 0.000
S06.2 Diffuse brain injury
0.709 0.291 0.000
Z93 Artificial opening status
0.709 0.291 0.000
B99-B99 Other infectious diseases
0.708 0.291 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.708 0.291 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.291 0.000
B65-B83 Helminthiases
0.708 0.291 0.000
B50-B64 Protozoal diseases
0.708 0.291 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.708 0.291 0.000
B15-B19 Viral hepatitis
0.708 0.291 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.291 0.000
A80-A89 Viral infections of the central nervous system
0.708 0.291 0.000
A75-A79 Rickettsioses
0.708 0.291 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.291 0.000
A65-A69 Other spirochaetal diseases
0.708 0.291 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.708 0.291 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.291 0.000
A15-A19 Tuberculosis
0.708 0.291 0.000
M21 Other acquired deformities of limbs
0.708 0.291 0.000
Chapter VIII Diseases of the ear and mastoid process
0.708 0.292 0.000
C77.1 Intrathoracic lymph nodes
0.707 0.293 0.000
R51 Headache
0.707 0.293 0.000
M23.8 Other internal derangements of knee
0.706 0.294 0.000
O80 Single spontaneous delivery
0.705 0.294 0.000
C25 Malignant neoplasm of pancreas
0.705 0.295 0.000
Z02 Examination and encounter for administrative purposes
0.705 0.295 0.000
C77.3 Axillary and upper limb lymph nodes
0.705 0.295 0.000
L60-L75 Disorders of skin appendages
0.704 0.296 0.000
S08 Traumatic amputation of part of head
0.703 0.297 0.000
S07 Crushing injury of head
0.703 0.297 0.000
S05 Injury of eye and orbit
0.703 0.297 0.000
S04 Injury of cranial nerves
0.703 0.297 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.703 0.297 0.000
Z38 Liveborn infants according to place of birth
0.703 0.297 0.000
Z32 Pregnancy examination and test
0.703 0.297 0.000
Z31 Procreative management
0.703 0.297 0.000
Z75 Problems related to medical facilities and other health care
0.702 0.298 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.702 0.298 0.000
L10-L14 Bullous disorders
0.701 0.299 0.000
E66.8 Other obesity
0.701 0.299 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.700 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.699 0.301 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.698 0.302 0.000
T42.4 Benzodiazepines
0.697 0.303 0.000
X60-X84 Intentional self-harm
0.697 0.303 0.000
E07 Other disorders of thyroid
0.697 0.303 0.000
M50 Cervical disk disorders
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.696 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
Y00-Y09 Assault
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.696 0.304 0.000
X50-X57 Overexertion, travel and privation
0.696 0.304 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X20-X29 Contact with venomous animals and plants
0.696 0.304 0.000
X10-X19 Contact with heat and hot substances
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
W50-W64 Exposure to animate mechanical forces
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V80-V89 Other land transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V20-V29 Motorcycle rider injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
S06.5 Traumatic subdural haemorrhage
0.696 0.304 0.000
E50-E64 Other nutritional deficiencies
0.696 0.304 0.000
I78 Diseases of capillaries
0.695 0.305 0.000
E87.2 Acidosis
0.695 0.305 0.000
E16 Other disorders of pancreatic internal secretion
0.695 0.305 0.000
Y52 Agents primarily affecting the cardiovascular system
0.694 0.306 0.000
Z95.3 Presence of xenogenic heart valve
0.694 0.306 0.000
S80 Superficial injury of lower leg
0.693 0.307 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.693 0.307 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.693 0.307 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.693 0.307 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.693 0.307 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.693 0.307 0.000
O43 Placental disorders
0.691 0.308 0.000
Y44 Agents primarily affecting blood constituents
0.691 0.309 0.000
E87.3 Alkalosis
0.691 0.309 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.690 0.310 0.000
I72 Other aneurysm
0.689 0.311 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.688 0.312 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.688 0.312 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.688 0.312 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.688 0.312 0.000
O74 Complications of anaesthesia during labour and delivery
0.688 0.312 0.000
O71 Other obstetric trauma
0.688 0.312 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.688 0.312 0.000
O66 Other obstructed labour
0.688 0.312 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.688 0.312 0.000
O62 Abnormalities of forces of labour
0.688 0.312 0.000
O61 Failed induction of labour
0.688 0.312 0.000
O60 Preterm delivery
0.688 0.312 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.688 0.312 0.000
Z57 Occupational exposure to risk-factors
0.687 0.313 0.000
R21 Rash and other nonspecific skin eruption
0.687 0.313 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.687 0.313 0.000
S50-S59 Injuries to the elbow and forearm
0.687 0.313 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.687 0.313 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.687 0.313 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.687 0.313 0.000
C21 Malignant neoplasm of anus and anal canal
0.687 0.313 0.000
C17 Malignant neoplasm of small intestine
0.687 0.313 0.000
C23 Malignant neoplasm of gallbladder
0.687 0.313 0.000
S00.7 Multiple superficial injuries of head
0.686 0.314 0.000
S00.5 Superficial injury of lip and oral cavity
0.686 0.314 0.000
S00.4 Superficial injury of ear
0.686 0.314 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.686 0.314 0.000
Z65 Problems related to other psychosocial circumstances
0.686 0.314 0.000
Z64 Problems related to certain psychosocial circumstances
0.686 0.314 0.000
Z62 Other problems related to upbringing
0.686 0.314 0.000
Z61 Problems related to negative life events in childhood
0.686 0.314 0.000
Z59 Problems related to housing and economic circumstances
0.686 0.314 0.000
Z58 Problems related to physical environment
0.686 0.314 0.000
Z56 Problems related to employment and unemployment
0.686 0.314 0.000
Z55 Problems related to education and literacy
0.686 0.314 0.000
Y57 Other and unspecified drugs and medicaments
0.686 0.314 0.000
M77 Other enthesopathies
0.686 0.314 0.000
M76 Enthesopathies of lower limb, excluding foot
0.686 0.314 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.686 0.314 0.000
M71 Other bursopathies
0.686 0.314 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.686 0.314 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.685 0.315 0.000
Z34.0 Supervision of normal first pregnancy
0.685 0.315 0.000
Z84 Family history of other conditions
0.685 0.315 0.000
Z81 Family history of mental and behavioural disorders
0.685 0.315 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.685 0.315 0.000
M40-M43 Deforming dorsopathies
0.684 0.315 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.684 0.316 0.000
Z91.5 Personal history of self-harm
0.684 0.316 0.000
S72 Fracture of femur
0.682 0.318 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.681 0.319 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.680 0.320 0.000
M89 Other disorders of bone
0.679 0.321 0.000
E13 Other specified diabetes mellitus
0.679 0.321 0.000
E12 Malnutrition-related diabetes mellitus
0.679 0.321 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.679 0.321 0.000
D45 Polycythaemia vera
0.678 0.322 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.677 0.322 0.000
T18 Foreign body in alimentary tract
0.677 0.322 0.000
Z74 Problems related to care-provider dependency
0.677 0.323 0.000
M79.9 Soft tissue disorder, unspecified
0.676 0.324 0.000
M79.5 Residual foreign body in soft tissue
0.676 0.324 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.676 0.324 0.000
M79.3 Panniculitis, unspecified
0.676 0.324 0.000
M79.2 Neuralgia and neuritis, unspecified
0.676 0.324 0.000
M79.1 Myalgia
0.676 0.324 0.000
O72 Postpartum haemorrhage
0.676 0.324 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.676 0.324 0.000
U80 Agent resistant to penicillin and related antibiotics
0.675 0.325 0.000
Z39 Postpartum care and examination
0.674 0.326 0.000
R20 Disturbances of skin sensation
0.674 0.326 0.000
G70-G73 Diseases of myoneural junction and muscle
0.674 0.326 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.674 0.326 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.674 0.326 0.000
R46 Symptoms and signs involving appearance and behaviour
0.674 0.326 0.000
R43 Disturbances of smell and taste
0.674 0.326 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.672 0.327 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.670 0.330 0.000
M54 Dorsalgia
0.669 0.331 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.669 0.331 0.000
O00-O08 Pregnancy with abortive outcome
0.668 0.332 0.000
M31 Other necrotising vasculopathies
0.668 0.332 0.000
D46 Myelodysplastic syndromes
0.668 0.332 0.000
L20-L30 Dermatitis and eczema
0.668 0.332 0.000
E04 Other non-toxic goitre
0.667 0.333 0.000
G58 Other mononeuropathies
0.667 0.333 0.000
S61 Open wound of wrist and hand
0.666 0.334 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.666 0.334 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.666 0.334 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.666 0.334 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.666 0.334 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.666 0.334 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.666 0.334 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.666 0.334 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.666 0.334 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.666 0.334 0.000
T36 Poisoning by systemic antibiotics
0.666 0.334 0.000
Z83.5 Family history of eye and ear disorders
0.665 0.335 0.000
L03.3 Cellulitis of trunk
0.663 0.337 0.000
R94 Abnormal results of function studies
0.663 0.337 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.662 0.338 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.662 0.338 0.000
M79.68 Pain in limb (Other)
0.661 0.339 0.000
M79.64 Pain in limb (Hand)
0.661 0.339 0.000
M79.61 Pain in limb (Shoulder region)
0.661 0.339 0.000
M79.60 Pain in limb (Multiple sites)
0.661 0.339 0.000
H53-H54 Visual disturbances and blindness
0.660 0.339 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.660 0.340 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.659 0.341 0.000
Z60.9 Problem related to social environment, unspecified
0.658 0.341 0.000
Z60.8 Other problems related to social environment
0.658 0.341 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.658 0.341 0.000
Z60.4 Social exclusion and rejection
0.658 0.341 0.000
Z60.3 Acculturation difficulty
0.658 0.341 0.000
Z60.1 Atypical parenting situation
0.658 0.341 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.658 0.341 0.000
Z37.0 Single live birth
0.658 0.342 0.000
E11.3 With ophthalmic complications
0.657 0.342 0.000
C51-C58 Malignant neoplasms of female genital organs
0.657 0.342 0.000
E11.8 With unspecified complications
0.656 0.344 0.000
E11.7 With multiple complications
0.656 0.344 0.000
E11.6 With other specified complications
0.656 0.344 0.000
E11.1 With ketoacidosis
0.656 0.344 0.000
E11.0 With coma
0.656 0.344 0.000
Z73 Problems related to life-management difficulty
0.656 0.344 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.656 0.344 0.000
W06 Fall involving bed
0.656 0.344 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.655 0.345 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.655 0.345 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.655 0.345 0.000
M34 Systemic sclerosis
0.655 0.345 0.000
M33 Dermatopolymyositis
0.655 0.345 0.000
M32 Systemic lupus erythematosus
0.655 0.345 0.000
M30 Polyarteritis nodosa and related conditions
0.655 0.345 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.655 0.345 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.655 0.345 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.655 0.345 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.655 0.345 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.655 0.345 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.655 0.345 0.000
M48.0 Spinal stenosis
0.655 0.345 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.655 0.345 0.000
B02 Zoster [herpes zoster]
0.654 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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