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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35348828
log Bayes Factor = 15.0337
Chromosome 3   position 177,179,941  (GRCh37) Explore rs35348828 on Ensembl!
Variant rs35348828 is part of Cluster X0100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
M20 Acquired deformities of fingers and toes
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
M20.1 Hallux valgus (acquired)
0.993 0.007 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.986 0.014 0.000
C79 Secondary malignant neoplasm of other sites
0.981 0.019 0.000
T81 Complications of procedures, not elsewhere classified
0.979 0.021 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.974 0.026 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.974 0.026 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.973 0.027 0.000
C64-C68 Malignant neoplasms of urinary tract
0.972 0.028 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.970 0.030 0.000
Chapter VII Diseases of the eye and adnexa
0.970 0.030 0.000
M50-M54 Other dorsopathies
0.962 0.038 0.000
C51-C58 Malignant neoplasms of female genital organs
0.956 0.044 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.950 0.050 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.949 0.051 0.000
G35 Multiple sclerosis
0.947 0.053 0.000
M24 Other specific joint derangements
0.945 0.055 0.000
Chapter IX Diseases of the circulatory system
0.943 0.057 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.941 0.059 0.000
M20.4 Other hammer toe(s) (acquired)
0.940 0.060 0.000
I20-I25 Ischaemic heart diseases
0.938 0.062 0.000
I21 Acute myocardial infarction
0.931 0.069 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.925 0.075 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.925 0.075 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.925 0.075 0.000
M25 Other joint disorders, not elsewhere classified
0.915 0.085 0.000
H40-H42 Glaucoma
0.915 0.085 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.914 0.086 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.913 0.087 0.000
G90-G99 Other disorders of the nervous system
0.910 0.090 0.000
M54 Dorsalgia
0.910 0.090 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.909 0.091 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.906 0.094 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.904 0.096 0.000
M51 Other intervertebral disk disorders
0.901 0.099 0.000
C78.0 Secondary malignant neoplasm of lung
0.900 0.100 0.000
W00-W19 Falls
0.896 0.104 0.000
Y43 Primarily systemic agents
0.896 0.104 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.890 0.110 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.887 0.113 0.000
S70-S79 Injuries to the hip and thigh
0.885 0.115 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.880 0.120 0.000
C56 Malignant neoplasm of ovary
0.879 0.121 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.878 0.122 0.000
I22 Subsequent myocardial infarction
0.876 0.124 0.000
H40 Glaucoma
0.876 0.124 0.000
D75 Other diseases of blood and blood-forming organs
0.873 0.127 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.872 0.128 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.871 0.129 0.000
G62 Other polyneuropathies
0.871 0.129 0.000
D45 Polycythaemia vera
0.871 0.129 0.000
W19 Unspecified fall
0.866 0.134 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.865 0.135 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.863 0.137 0.000
W19.9 Unspecified place
0.862 0.138 0.000
Q60-Q64 Congenital malformations of the urinary system
0.857 0.143 0.000
Y40 Systemic antibiotics
0.856 0.144 0.000
M51.2 Other specified intervertebral disk displacement
0.853 0.147 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.852 0.148 0.000
Chapter I Certain infectious and parasitic diseases
0.852 0.148 0.000
X50-X57 Overexertion, travel and privation
0.849 0.151 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.845 0.155 0.000
I21.4 Acute subendocardial myocardial infarction
0.844 0.156 0.000
H18 Other disorders of cornea
0.843 0.157 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.842 0.158 0.000
H40.9 Glaucoma, unspecified
0.842 0.158 0.000
M20.5 Other deformities of toe(s) (acquired)
0.841 0.159 0.000
S80-S89 Injuries to the knee and lower leg
0.840 0.160 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.839 0.161 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.838 0.162 0.000
D37.4 Colon
0.836 0.164 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.835 0.164 0.000
M54.9 Dorsalgia, unspecified
0.834 0.166 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.833 0.167 0.000
C66 Malignant neoplasm of ureter
0.831 0.169 0.000
C78.7 Secondary malignant neoplasm of liver
0.831 0.169 0.000
G37 Other demyelinating diseases of central nervous system
0.830 0.170 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.830 0.170 0.000
M05-M14 Inflammatory polyarthropathies
0.829 0.171 0.000
M40-M43 Deforming dorsopathies
0.828 0.172 0.000
T93 Sequelae of injuries of lower limb
0.828 0.172 0.000
C53 Malignant neoplasm of cervix uteri
0.823 0.177 0.000
H10-H13 Disorders of conjunctiva
0.821 0.179 0.000
M70-M79 Other soft tissue disorders
0.821 0.179 0.000
I21.9 Acute myocardial infarction, unspecified
0.820 0.180 0.000
I80 Phlebitis and thrombophlebitis
0.820 0.180 0.000
M25.5 Pain in joint
0.816 0.184 0.000
M80-M85 Disorders of bone density and structure
0.815 0.185 0.000
V40-V49 Car occupant injured in transport accident
0.815 0.185 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.813 0.187 0.000
S20-S29 Injuries to the thorax
0.812 0.188 0.000
M24.1 Other articular cartilage disorders
0.812 0.188 0.000
W50-W64 Exposure to animate mechanical forces
0.811 0.189 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.810 0.189 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.810 0.190 0.000
M20.2 Hallux rigidus
0.810 0.190 0.000
Y43.3 Other antineoplastic drugs
0.806 0.194 0.000
C81 Hodgkin's disease
0.806 0.194 0.000
T66-T78 Other and unspecified effects of external causes
0.803 0.197 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.802 0.198 0.000
D75.1 Secondary polycythaemia
0.801 0.199 0.000
S10-S19 Injuries to the neck
0.800 0.200 0.000
S40-S49 Injuries to the shoulder and upper arm
0.796 0.204 0.000
C78.2 Secondary malignant neoplasm of pleura
0.794 0.205 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.793 0.207 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.793 0.207 0.000
D10-D36 Benign neoplasms
0.793 0.207 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.792 0.208 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.788 0.212 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.787 0.213 0.000
Q80-Q89 Other congenital malformations
0.787 0.213 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.787 0.213 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.786 0.214 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.786 0.214 0.000
D37.5 Rectum
0.784 0.216 0.000
M25.56 Pain in joint (Lower leg)
0.784 0.216 0.000
I85 Oesophageal varices
0.781 0.219 0.000
D37.2 Small intestine
0.779 0.221 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.779 0.221 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.779 0.221 0.000
G62.9 Polyneuropathy, unspecified
0.779 0.221 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.778 0.222 0.000
H18.5 Hereditary corneal dystrophies
0.778 0.222 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.777 0.223 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.776 0.224 0.000
X60-X84 Intentional self-harm
0.776 0.224 0.000
Y00-Y09 Assault
0.775 0.225 0.000
H40.1 Primary open-angle glaucoma
0.775 0.225 0.000
C77.5 Intrapelvic lymph nodes
0.774 0.226 0.000
M54.2 Cervicalgia
0.774 0.226 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.773 0.227 0.000
M25.7 Osteophyte
0.772 0.227 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.772 0.228 0.000
D17 Benign lipomatous neoplasm
0.772 0.228 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.771 0.229 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.771 0.229 0.000
X10-X19 Contact with heat and hot substances
0.771 0.229 0.000
C52 Malignant neoplasm of vagina
0.770 0.230 0.000
S50-S59 Injuries to the elbow and forearm
0.770 0.230 0.000
M20.3 Other deformity of hallux (acquired)
0.769 0.231 0.000
D72 Other disorders of white blood cells
0.769 0.231 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.768 0.232 0.000
Chapter XXII Codes for special purposes
0.767 0.233 0.000
S80 Superficial injury of lower leg
0.767 0.233 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.764 0.236 0.000
T90 Sequelae of injuries of head
0.762 0.238 0.000
C79.6 Secondary malignant neoplasm of ovary
0.762 0.238 0.000
M34 Systemic sclerosis
0.761 0.239 0.000
T79-T79 Certain early complications of trauma
0.761 0.239 0.000
I25 Chronic ischaemic heart disease
0.760 0.240 0.000
Y43.1 Antineoplastic antimetabolites
0.760 0.240 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.760 0.240 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.759 0.241 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.758 0.242 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.758 0.242 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.756 0.244 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.756 0.244 0.000
S72 Fracture of femur
0.756 0.244 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.756 0.244 0.000
C92 Myeloid leukaemia
0.751 0.249 0.000
A30-A49 Other bacterial diseases
0.751 0.249 0.000
G70-G73 Diseases of myoneural junction and muscle
0.750 0.250 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.750 0.250 0.000
D37.7 Other digestive organs
0.749 0.251 0.000
T81.9 Unspecified complication of procedure
0.748 0.252 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.748 0.252 0.000
Q50-Q56 Congenital malformations of genital organs
0.745 0.255 0.000
M31 Other necrotising vasculopathies
0.744 0.256 0.000
T87 Complications peculiar to reattachment and amputation
0.743 0.257 0.000
H11 Other disorders of conjunctiva
0.743 0.257 0.000
X51 Travel and motion
0.743 0.257 0.000
Y40.0 Penicillins
0.743 0.257 0.000
M54.1 Radiculopathy
0.742 0.258 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.742 0.258 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.739 0.261 0.000
Q61 Cystic kidney disease
0.739 0.261 0.000
D73 Diseases of spleen
0.739 0.261 0.000
G62.8 Other specified polyneuropathies
0.738 0.262 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.737 0.263 0.000
C77.9 Lymph node, unspecified
0.737 0.263 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.735 0.265 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.734 0.266 0.000
Y48 Anaesthetics and therapeutic gases
0.734 0.266 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.734 0.266 0.000
T17 Foreign body in respiratory tract
0.733 0.267 0.000
M60-M63 Disorders of muscles
0.732 0.268 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.731 0.268 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.730 0.269 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.730 0.270 0.000
M24.5 Contracture of joint
0.728 0.272 0.000
M91-M94 Chondropathies
0.728 0.272 0.000
C53.9 Cervix uteri, unspecified
0.728 0.272 0.000
G96 Other disorders of central nervous system
0.728 0.272 0.000
Q63 Other congenital malformations of kidney
0.727 0.273 0.000
T86 Failure and rejection of transplanted organs and tissues
0.727 0.273 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.726 0.274 0.000
O00-O08 Pregnancy with abortive outcome
0.724 0.276 0.000
T31 Burns classified according to extent of body surface involved
0.724 0.276 0.000
T98 Sequelae of other and unspecified effects of external causes
0.723 0.277 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.722 0.278 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.721 0.279 0.000
M86-M90 Other osteopathies
0.720 0.279 0.000
T82.3 Mechanical complication of other vascular grafts
0.720 0.280 0.000
M41 Scoliosis
0.720 0.280 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.720 0.280 0.000
M25.4 Effusion of joint
0.719 0.280 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.718 0.282 0.000
X20-X29 Contact with venomous animals and plants
0.718 0.282 0.000
S82 Fracture of lower leg, including ankle
0.717 0.283 0.000
I25.2 Old myocardial infarction
0.717 0.283 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.717 0.283 0.000
S60-S69 Injuries to the wrist and hand
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C15-C26 Malignant neoplasms of digestive organs
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
C81.1 Nodular sclerosis
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
M51.8 Other specified intervertebral disk disorders
0.715 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.286 0.000
S20 Superficial injury of thorax
0.713 0.287 0.000
I82 Other venous embolism and thrombosis
0.713 0.287 0.000
V10-V19 Pedal cyclist injured in transport accident
0.713 0.287 0.000
I86 Varicose veins of other sites
0.713 0.287 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.712 0.288 0.000
M53 Other dorsopathies, not elsewhere classified
0.712 0.288 0.000
M13 Other arthritis
0.711 0.289 0.000
H20 Iridocyclitis
0.710 0.290 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.709 0.291 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.709 0.291 0.000
T18 Foreign body in alimentary tract
0.708 0.292 0.000
Y57 Other and unspecified drugs and medicaments
0.708 0.292 0.000
C51 Malignant neoplasm of vulva
0.707 0.293 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.707 0.293 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.707 0.293 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.707 0.293 0.000
M25.77 Osteophyte (Ankle and foot)
0.705 0.295 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.705 0.295 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.704 0.296 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.702 0.298 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.702 0.298 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.702 0.298 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.702 0.298 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.701 0.299 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.701 0.299 0.000
M54.5 Low back pain
0.700 0.300 0.000
I89.0 Lymphoedema, not elsewhere classified
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
Y59 Other and unspecified vaccines and biological substances
0.698 0.302 0.000
Y58 Bacterial vaccines
0.698 0.302 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.698 0.302 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.698 0.302 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.698 0.302 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.698 0.302 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.698 0.302 0.000
D36 Benign neoplasm of other and unspecified sites
0.698 0.302 0.000
G36 Other acute disseminated demyelination
0.697 0.302 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.697 0.303 0.000
C65 Malignant neoplasm of renal pelvis
0.697 0.303 0.000
Y52 Agents primarily affecting the cardiovascular system
0.697 0.303 0.000
H16 Keratitis
0.696 0.304 0.000
M65-M68 Disorders of synovium and tendon
0.696 0.304 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.696 0.304 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.696 0.304 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.696 0.304 0.000
C79.2 Secondary malignant neoplasm of skin
0.695 0.305 0.000
S70 Superficial injury of hip and thigh
0.692 0.307 0.000
S80.8 Other superficial injuries of lower leg
0.691 0.309 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.691 0.309 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.690 0.310 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.690 0.310 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.690 0.310 0.000
M54.22 Cervicalgia (Cervical region)
0.686 0.314 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.685 0.314 0.000
C58 Malignant neoplasm of placenta
0.685 0.314 0.000
Y41.0 Sulphonamides
0.685 0.315 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.685 0.315 0.000
D70 Agranulocytosis
0.685 0.315 0.000
D38.1 Trachea, bronchus and lung
0.684 0.315 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.684 0.316 0.000
S72.4 Fracture of lower end of femur
0.684 0.316 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.316 0.000
H21 Other disorders of iris and ciliary body
0.682 0.318 0.000
D47.1 Chronic myeloproliferative disease
0.682 0.318 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.682 0.318 0.000
T93.0 Sequelae of open wound of lower limb
0.681 0.318 0.000
G95 Other diseases of spinal cord
0.681 0.319 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.680 0.320 0.000
Q35-Q37 Cleft lip and cleft palate
0.680 0.320 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.680 0.320 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.680 0.320 0.000
G62.0 Drug-induced polyneuropathy
0.680 0.320 0.000
H25-H28 Disorders of lens
0.680 0.320 0.000
D46 Myelodysplastic syndromes
0.680 0.320 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.679 0.321 0.000
S79 Other and unspecified injuries of hip and thigh
0.679 0.321 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.678 0.322 0.000
M71 Other bursopathies
0.678 0.322 0.000
M24.9 Joint derangement, unspecified
0.677 0.322 0.000
M24.7 Protrusio acetabuli
0.677 0.322 0.000
M24.6 Ankylosis of joint
0.677 0.322 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.677 0.322 0.000
M24.2 Disorder of ligament
0.677 0.322 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.677 0.323 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.677 0.323 0.000
M84 Disorders of continuity of bone
0.676 0.324 0.000
I00-I02 Acute rheumatic fever
0.676 0.324 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.676 0.324 0.000
O03 Spontaneous abortion
0.675 0.325 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.675 0.325 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.675 0.325 0.000
D37.9 Digestive organ, unspecified
0.675 0.325 0.000
D37.6 Liver, gallbladder and bile ducts
0.675 0.325 0.000
D37.3 Appendix
0.675 0.325 0.000
D37.1 Stomach
0.675 0.325 0.000
D75.2 Essential thrombocytosis
0.675 0.325 0.000
Y44 Agents primarily affecting blood constituents
0.673 0.327 0.000
I23 Certain current complications following acute myocardial infarction
0.673 0.327 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.673 0.327 0.000
H52 Disorders of refraction and accommodation
0.672 0.328 0.000
Chapter VIII Diseases of the ear and mastoid process
0.672 0.328 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.671 0.329 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.671 0.329 0.000
Chapter V Mental and behavioural disorders
0.671 0.329 0.000
S43.0 Dislocation of shoulder joint
0.670 0.330 0.000
C81.9 Hodgkin's disease, unspecified
0.670 0.330 0.000
V80-V89 Other land transport accidents
0.669 0.331 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.668 0.332 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.668 0.332 0.000
W08 Fall involving other furniture
0.667 0.332 0.000
M25.50 Pain in joint (Multiple sites)
0.667 0.333 0.000
X51.9 Unspecified place
0.667 0.333 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.666 0.334 0.000
G91 Hydrocephalus
0.666 0.334 0.000
G90 Disorders of autonomic nervous system
0.664 0.336 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.663 0.337 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.663 0.337 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.663 0.337 0.000
G60 Hereditary and idiopathic neuropathy
0.663 0.337 0.000
G64 Other disorders of peripheral nervous system
0.663 0.337 0.000
T95 Sequelae of burns, corrosions and frostbite
0.663 0.337 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.663 0.337 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.663 0.337 0.000
I81 Portal vein thrombosis
0.663 0.337 0.000
I24 Other acute ischaemic heart diseases
0.662 0.338 0.000
I05-I09 Chronic rheumatic heart diseases
0.662 0.338 0.000
I85.9 Oesophageal varices without bleeding
0.662 0.338 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.661 0.338 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.661 0.339 0.000
I87 Other disorders of veins
0.661 0.339 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.661 0.339 0.000
G93 Other disorders of brain
0.661 0.339 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.660 0.339 0.000
C80 Malignant neoplasm without specification of site
0.660 0.340 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.660 0.340 0.000
M24.0 Loose body in joint
0.658 0.341 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.658 0.342 0.000
Y40.3 Macrolides
0.658 0.342 0.000
T91 Sequelae of injuries of neck and trunk
0.657 0.343 0.000
T51 Toxic effect of alcohol
0.657 0.343 0.000
M25.9 Joint disorder, unspecified
0.656 0.344 0.000
M25.2 Flail joint
0.656 0.344 0.000
M25.1 Fistula of joint
0.656 0.344 0.000
H42 Glaucoma in diseases classified elsewhere
0.656 0.344 0.000
D55-D59 Haemolytic anaemias
0.656 0.344 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.655 0.345 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.654 0.345 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.654 0.345 0.000
H17 Corneal scars and opacities
0.654 0.345 0.000
H15 Disorders of sclera
0.654 0.345 0.000
G61 Inflammatory polyneuropathy
0.654 0.346 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.653 0.347 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.653 0.347 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.653 0.347 0.000
G92 Toxic encephalopathy
0.653 0.347 0.000
C77.1 Intrathoracic lymph nodes
0.653 0.347 0.000
M54.8 Other dorsalgia
0.652 0.347 0.000
M54.0 Panniculitis affecting regions of neck and back
0.652 0.347 0.000
T82.1 Mechanical complication of cardiac electronic device
0.652 0.348 0.000
M77 Other enthesopathies
0.652 0.348 0.000
H11.3 Conjunctival haemorrhage
0.651 0.349 0.000
M25.0 Haemarthrosis
0.650 0.350 0.000
T78 Adverse effects, not elsewhere classified
0.649 0.351 0.000
Q00-Q07 Congenital malformations of the nervous system
0.648 0.352 0.000
D74 Methaemoglobinaemia
0.648 0.352 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.648 0.352 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.648 0.352 0.000
D72.8 Other specified disorders of white blood cells
0.648 0.352 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.647 0.353 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.647 0.353 0.000
M51.3 Other specified intervertebral disk degeneration
0.646 0.354 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.646 0.354 0.000
M51.9 Intervertebral disk disorder, unspecified
0.646 0.354 0.000
M51.4 Schmorl's nodes
0.646 0.354 0.000
M41.9 Scoliosis, unspecified
0.643 0.357 0.000
C88 Malignant immunoproliferative diseases
0.643 0.357 0.000
H18.9 Disorder of cornea, unspecified
0.643 0.357 0.000
W18 Other fall on same level
0.642 0.357 0.000
W17 Other fall from one level to another
0.642 0.357 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.642 0.357 0.000
W15 Fall from cliff
0.642 0.357 0.000
W14 Fall from tree
0.642 0.357 0.000
W12 Fall on and from scaffolding
0.642 0.357 0.000
W11 Fall on and from ladder
0.642 0.357 0.000
W09 Fall involving playground equipment
0.642 0.357 0.000
W05 Fall involving wheelchair
0.642 0.357 0.000
W04 Fall while being carried or supported by other persons
0.642 0.357 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.642 0.357 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.642 0.357 0.000
W00 Fall on same level involving ice and snow
0.642 0.357 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.642 0.358 0.000
Y43.9 Primarily systemic agent, unspecified
0.642 0.358 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.642 0.358 0.000
Y43.6 Enzymes, not elsewhere classified
0.642 0.358 0.000
Y43.5 Acidifying and alkalising agents
0.642 0.358 0.000
Y43.2 Antineoplastic natural products
0.642 0.358 0.000
Y43.0 Antiallergic and antiemetic drugs
0.642 0.358 0.000
H46 Optic neuritis
0.642 0.358 0.000
T31.0 Burns involving less than 10% of body surface
0.641 0.359 0.000
S20.2 Contusion of thorax
0.641 0.359 0.000
S90-S99 Injuries to the ankle and foot
0.640 0.359 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.641 0.359 0.000
M25.3 Other instability of joint
0.640 0.360 0.000
I85.0 Oesophageal varices with bleeding
0.638 0.362 0.000
I88 Nonspecific lymphadenitis
0.638 0.362 0.000
M25.72 Osteophyte (Upper arm)
0.637 0.363 0.000
A41 Other septicaemia
0.637 0.363 0.000
M95.0 Acquired deformity of nose
0.637 0.363 0.000
H55-H59 Other disorders of eye and adnexa
0.636 0.364 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.636 0.364 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.636 0.364 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.636 0.364 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.636 0.364 0.000
C07 Malignant neoplasm of parotid gland
0.635 0.365 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.635 0.365 0.000
S78 Traumatic amputation of hip and thigh
0.635 0.365 0.000
S77 Crushing injury of hip and thigh
0.635 0.365 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.635 0.365 0.000
S75 Injury of blood vessels at hip and thigh level
0.635 0.365 0.000
S74 Injury of nerves at hip and thigh level
0.635 0.365 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.635 0.365 0.000
G30-G32 Other degenerative diseases of the nervous system
0.634 0.365 0.000
A00-A09 Intestinal infectious diseases
0.634 0.366 0.000
S82.5 Fracture of medial malleolus
0.634 0.366 0.000
T93.2 Sequelae of other fractures of lower limb
0.634 0.366 0.000
M54.59 Low back pain (Site unspecified)
0.634 0.366 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.634 0.366 0.000
Q61.3 Polycystic kidney, unspecified
0.633 0.367 0.000
W13 Fall from, out of or through building or structure
0.633 0.367 0.000
S71 Open wound of hip and thigh
0.633 0.367 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.632 0.367 0.000
S72.40 Fracture of lower end of femur (closed)
0.632 0.368 0.000
C45 Mesothelioma
0.632 0.368 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.631 0.369 0.000
C95 Leukaemia of unspecified cell type
0.631 0.369 0.000
C94 Other leukaemias of specified cell type
0.631 0.369 0.000
C93 Monocytic leukaemia
0.631 0.369 0.000
C86 Other specified types of T/NK-cell lymphoma
0.631 0.369 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.631 0.369 0.000
T90.9 Sequelae of unspecified injury of head
0.631 0.369 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.630 0.370 0.000
M79.5 Residual foreign body in soft tissue
0.630 0.370 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.629 0.371 0.000
D18 Haemangioma and lymphangioma, any site
0.629 0.371 0.000
I22.8 Subsequent myocardial infarction of other sites
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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