TreeWAS – Variant ID: rs356150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter IX Diseases of the circulatory system	0.608	0.392	0.000
I20-I25 Ischaemic heart diseases	0.598	0.402	0.000
# Top node	0.595	0.405	0.000
I10-I15 Hypertensive diseases	0.571	0.429	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.570	0.430	0.000
I25 Chronic ischaemic heart disease	0.561	0.439	0.000
I20 Angina pectoris	0.548	0.452	0.000
I10 Essential (primary) hypertension	0.543	0.457	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.512	0.488	0.000
Chapter XXI Factors influencing health status and contact with health services	0.510	0.490	0.000
E70-E90 Metabolic disorders	0.501	0.499	0.000
Chapter XX External causes of morbidity and mortality	0.501	0.499	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.500	0.500	0.000
E10-E14 Diabetes mellitus	0.497	0.503	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.487	0.512	0.000
Chapter X Diseases of the respiratory system	0.486	0.514	0.000
I20.9 Angina pectoris, unspecified	0.486	0.514	0.000
I30-I52 Other forms of heart disease	0.484	0.516	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.483	0.517	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.475	0.525	0.000
I25.1 Atherosclerotic heart disease	0.469	0.531	0.000
Chapter II Neoplasms	0.468	0.532	0.000
Chapter V Mental and behavioural disorders	0.459	0.541	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.459	0.541	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.452	0.548	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.451	0.549	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.451	0.549	0.000
I20.0 Unstable angina	0.451	0.549	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.449	0.550	0.000
M15-M19 Arthrosis	0.449	0.550	0.000
E65-E68 Obesity and other hyperalimentation	0.449	0.551	0.000
E11 Non-insulin-dependent diabetes mellitus	0.447	0.553	0.000
I21 Acute myocardial infarction	0.446	0.554	0.000
I24 Other acute ischaemic heart diseases	0.445	0.555	0.000
I60-I69 Cerebrovascular diseases	0.444	0.556	0.000
I25.2 Old myocardial infarction	0.444	0.556	0.000
E00-E07 Disorders of thyroid gland	0.443	0.557	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.441	0.559	0.000
I05-I09 Chronic rheumatic heart diseases	0.440	0.560	0.000
I22 Subsequent myocardial infarction	0.437	0.562	0.000
I00-I02 Acute rheumatic fever	0.436	0.564	0.000
Chapter XXII Codes for special purposes	0.435	0.565	0.000
I23 Certain current complications following acute myocardial infarction	0.429	0.571	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.427	0.573	0.000
Chapter VI Diseases of the nervous system	0.421	0.579	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.420	0.580	0.000
E20-E35 Disorders of other endocrine glands	0.418	0.582	0.000
I12 Hypertensive renal disease	0.417	0.583	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.415	0.585	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.414	0.585	0.000
I11 Hypertensive heart disease	0.412	0.588	0.000
I15 Secondary hypertension	0.411	0.588	0.000
E40-E46 Malnutrition	0.410	0.590	0.000
I13 Hypertensive heart and renal disease	0.410	0.590	0.000
E11.9 Without complications	0.407	0.593	0.000
I20.8 Other forms of angina pectoris	0.406	0.594	0.000
I25.5 Ischaemic cardiomyopathy	0.406	0.594	0.000
I25.3 Aneurysm of heart	0.404	0.596	0.000
E50-E64 Other nutritional deficiencies	0.404	0.596	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.403	0.597	0.000
I25.4 Coronary artery aneurysm	0.403	0.597	0.000
I25.6 Silent myocardial ischaemia	0.402	0.598	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.400	0.600	0.000
I83 Varicose veins of lower extremities	0.398	0.602	0.000
M20-M25 Other joint disorders	0.398	0.602	0.000
I20.1 Angina pectoris with documented spasm	0.397	0.603	0.000
E78.0 Pure hypercholesterolaemia	0.396	0.604	0.000
M05-M14 Inflammatory polyarthropathies	0.395	0.605	0.000
J40-J47 Chronic lower respiratory diseases	0.394	0.606	0.000
J90-J94 Other diseases of pleura	0.393	0.607	0.000
Z51 Other medical care	0.390	0.610	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.388	0.612	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.387	0.613	0.000
M70-M79 Other soft tissue disorders	0.384	0.616	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.382	0.617	0.000
I50 Heart failure	0.382	0.618	0.000
J20-J22 Other acute lower respiratory infections	0.382	0.618	0.000
Chapter I Certain infectious and parasitic diseases	0.382	0.618	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.382	0.618	0.000
I73 Other peripheral vascular diseases	0.381	0.618	0.000
Z53 Persons encountering health services for specifie procedures, not carried out	0.381	0.619	0.000
Chapter VIII Diseases of the ear and mastoid process	0.377	0.623	0.000
Chapter XIV Diseases of the genitourinary system	0.376	0.624	0.000
L20-L30 Dermatitis and eczema	0.375	0.625	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.374	0.626	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.374	0.626	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.374	0.626	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.373	0.627	0.000
M65-M68 Disorders of synovium and tendon	0.373	0.627	0.000
W00-W19 Falls	0.372	0.628	0.000
M91-M94 Chondropathies	0.371	0.628	0.000
E83 Disorders of mineral metabolism	0.371	0.629	0.000
M60-M63 Disorders of muscles	0.371	0.629	0.000
M86-M90 Other osteopathies	0.371	0.629	0.000
M40-M43 Deforming dorsopathies	0.371	0.629	0.000
M00-M03 Infectious arthropathies	0.369	0.631	0.000
L50-L54 Urticaria and erythema	0.367	0.633	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.366	0.634	0.000
V10-V19 Pedal cyclist injured in transport accident	0.365	0.635	0.000
X60-X84 Intentional self-harm	0.364	0.635	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.364	0.636	0.000
W20-W49 Exposure to inanimate mechanical forces	0.364	0.636	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.363	0.637	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.363	0.637	0.000
I42 Cardiomyopathy	0.362	0.637	0.000
W50-W64 Exposure to animate mechanical forces	0.362	0.638	0.000
I51 Complications and ill-defined descriptions of heart disease	0.362	0.638	0.000
V20-V29 Motorcycle rider injured in transport accident	0.362	0.638	0.000
V40-V49 Car occupant injured in transport accident	0.362	0.638	0.000
E66 Obesity	0.362	0.638	0.000
I47 Paroxysmal tachycardia	0.361	0.639	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.361	0.639	0.000
E85 Amyloidosis	0.361	0.639	0.000
I80 Phlebitis and thrombophlebitis	0.361	0.639	0.000
V80-V89 Other land transport accidents	0.361	0.639	0.000
Y00-Y09 Assault	0.360	0.639	0.000
X50-X57 Overexertion, travel and privation	0.360	0.639	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.360	0.639	0.000
E14 Unspecified diabetes mellitus	0.360	0.640	0.000
M16 Coxarthrosis [arthrosis of hip]	0.360	0.640	0.000
E73 Lactose intolerance	0.360	0.640	0.000
V01-V09 Pedestrian injured in transport accident	0.360	0.640	0.000
L10-L14 Bullous disorders	0.360	0.640	0.000
X10-X19 Contact with heat and hot substances	0.360	0.640	0.000
X20-X29 Contact with venomous animals and plants	0.360	0.640	0.000
E74 Other disorders of carbohydrate metabolism	0.360	0.640	0.000
W75-W84 Other accidental threats to breathing	0.360	0.640	0.000
L40-L45 Papulosquamous disorders	0.360	0.640	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.359	0.640	0.000
E84 Cystic fibrosis	0.359	0.640	0.000
E79 Disorders of purine and pyrimidine metabolism	0.359	0.640	0.000
Y10-Y34 Event of undetermined intent	0.359	0.640	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.359	0.640	0.000
E72 Other disorders of amino-acid metabolism	0.359	0.640	0.000
X00-X09 Exposure to smoke, fire and flames	0.359	0.640	0.000
V98-V99 Other and unspecified transport accidents	0.359	0.640	0.000
E70 Disorders of aromatic amino-acid metabolism	0.359	0.641	0.000
E77 Disorders of glycoprotein metabolism	0.359	0.641	0.000
V95-V97 Air and space transport accidents	0.359	0.641	0.000
V70-V79 Bus occupant injured in transport accident	0.359	0.641	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.359	0.641	0.000
E76 Disorders of glycosaminoglycan metabolism	0.359	0.641	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.359	0.641	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.359	0.641	0.000
X30-X39 Exposure to forces of nature	0.359	0.641	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.359	0.641	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.359	0.641	0.000
Y35-Y36 Legal intervention and operations of war	0.359	0.641	0.000
X85-X99 Assault	0.359	0.641	0.000
W65-W74 Accidental drowning and submersion	0.359	0.641	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.359	0.641	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.358	0.641	0.000
E13 Other specified diabetes mellitus	0.358	0.642	0.000
M17 Gonarthrosis [arthrosis of knee]	0.357	0.643	0.000
E12 Malnutrition-related diabetes mellitus	0.356	0.643	0.000
I35 Nonrheumatic aortic valve disorders	0.356	0.643	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.356	0.644	0.000
I74 Arterial embolism and thrombosis	0.356	0.644	0.000
E86 Volume depletion	0.356	0.644	0.000
E78.5 Hyperlipidaemia, unspecified	0.356	0.644	0.000
Chapter VII Diseases of the eye and adnexa	0.355	0.645	0.000
J95-J99 Other diseases of the respiratory system	0.355	0.645	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.355	0.645	0.000
C15-C26 Malignant neoplasms of digestive organs	0.355	0.645	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.355	0.645	0.000
Z50 Care involving use of rehabilitation procedures	0.355	0.645	0.000
I87 Other disorders of veins	0.354	0.646	0.000
I86 Varicose veins of other sites	0.354	0.646	0.000
I82 Other venous embolism and thrombosis	0.354	0.646	0.000
Z45 Adjustment and management of implanted device	0.354	0.646	0.000
M80-M85 Disorders of bone density and structure	0.353	0.647	0.000
E88 Other metabolic disorders	0.352	0.648	0.000
V90-V94 Water transport accidents	0.352	0.648	0.000
I81 Portal vein thrombosis	0.352	0.648	0.000
I72 Other aneurysm	0.352	0.648	0.000
I77 Other disorders of arteries and arterioles	0.351	0.649	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.351	0.649	0.000
M19 Other arthrosis	0.351	0.649	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.350	0.649	0.000
I45 Other conduction disorders	0.350	0.650	0.000
I70 Atherosclerosis	0.350	0.650	0.000
I33 Acute and subacute endocarditis	0.350	0.650	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.349	0.651	0.000
J60-J70 Lung diseases due to external agents	0.349	0.651	0.000
L60-L75 Disorders of skin appendages	0.349	0.651	0.000
I36 Nonrheumatic tricuspid valve disorders	0.348	0.651	0.000
I63 Cerebral infarction	0.348	0.651	0.000
I37 Pulmonary valve disorders	0.348	0.652	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.348	0.652	0.000
I40 Acute myocarditis	0.348	0.652	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.348	0.652	0.000
I52 Other heart disorders in diseases classified elsewhere	0.347	0.652	0.000
I48 Atrial fibrillation and flutter	0.347	0.652	0.000
I41 Myocarditis in diseases classified elsewhere	0.347	0.652	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.347	0.652	0.000
I32 Pericarditis in diseases classified elsewhere	0.347	0.652	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.347	0.653	0.000
I46 Cardiac arrest	0.347	0.653	0.000
M45-M49 Spondylopathies	0.345	0.654	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.345	0.654	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.345	0.655	0.000
I85 Oesophageal varices	0.345	0.655	0.000
I34 Nonrheumatic mitral valve disorders	0.345	0.655	0.000
I49 Other cardiac arrhythmias	0.345	0.655	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.344	0.655	0.000
J09-J18 Influenza and pneumonia	0.344	0.656	0.000
C50-C50 Malignant neoplasm of breast	0.344	0.656	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.344	0.656	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.344	0.656	0.000
I78 Diseases of capillaries	0.343	0.657	0.000
E10 Insulin-dependent diabetes mellitus	0.343	0.657	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.342	0.658	0.000
I71 Aortic aneurysm and dissection	0.342	0.658	0.000
D00-D09 In situ neoplasms	0.342	0.658	0.000
E03 Other hypothyroidism	0.341	0.659	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.341	0.659	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.341	0.659	0.000
I88 Nonspecific lymphadenitis	0.340	0.659	0.000
I26 Pulmonary embolism	0.340	0.660	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.340	0.660	0.000
I30 Acute pericarditis	0.339	0.660	0.000
I31 Other diseases of pericardium	0.339	0.661	0.000
I38 Endocarditis, valve unspecified	0.339	0.661	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.338	0.661	0.000
O60-O75 Complications of labour and delivery	0.338	0.662	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.337	0.663	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.337	0.663	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.336	0.664	0.000
Z48 Other surgical follow-up care	0.336	0.664	0.000
C51-C58 Malignant neoplasms of female genital organs	0.336	0.664	0.000
M18 Arthrosis of first carpometacarpal joint	0.335	0.664	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.335	0.665	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.334	0.666	0.000
E11.3 With ophthalmic complications	0.333	0.667	0.000
I95 Hypotension	0.333	0.667	0.000
Z49 Care involving dialysis	0.333	0.667	0.000
I44 Atrioventricular and left bundle-branch block	0.333	0.667	0.000
F60-F69 Disorders of adult personality and behaviour	0.333	0.667	0.000
J00-J06 Acute upper respiratory infections	0.332	0.667	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.332	0.668	0.000
I84 Haemorrhoids	0.332	0.668	0.000
I69 Sequelae of cerebrovascular disease	0.332	0.668	0.000
F80-F89 Disorders of psychological development	0.331	0.668	0.000
F99-F99 Unspecified mental disorder	0.331	0.669	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.331	0.669	0.000
Z54 Convalescence	0.331	0.669	0.000
I21.4 Acute subendocardial myocardial infarction	0.331	0.669	0.000
Z44 Fitting and adjustment of external prosthetic device	0.330	0.670	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.330	0.670	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.330	0.670	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.330	0.670	0.000
F70-F79 Mental retardation	0.330	0.670	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.330	0.670	0.000
O85-O92 Complications predominantly related to the puerperium	0.328	0.672	0.000
Z43 Attention to artificial openings	0.328	0.672	0.000
I24.8 Other forms of acute ischaemic heart disease	0.327	0.672	0.000
I60 Subarachnoid haemorrhage	0.327	0.672	0.000
Z41 Procedures for purposes other than remedying health state	0.327	0.673	0.000
Z40 Prophylactic surgery	0.327	0.673	0.000
E11.4 With neurological complications	0.327	0.673	0.000
Z42 Follow-up care involving plastic surgery	0.326	0.674	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.326	0.674	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.326	0.674	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.326	0.674	0.000
I99 Other and unspecified disorders of circulatory system	0.325	0.674	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.325	0.675	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.325	0.675	0.000
I28 Other diseases of pulmonary vessels	0.325	0.675	0.000
E04 Other non-toxic goitre	0.325	0.675	0.000
E11.5 With peripheral circulatory complications	0.325	0.675	0.000
E78.2 Mixed hyperlipidaemia	0.324	0.676	0.000
Z51.1 Chemotherapy session for neoplasm	0.324	0.676	0.000
M15 Polyarthrosis	0.324	0.676	0.000
I27 Other pulmonary heart diseases	0.324	0.676	0.000
E78.8 Other disorders of lipoprotein metabolism	0.324	0.676	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.323	0.676	0.000
E11.2 With renal complications	0.323	0.677	0.000
E78.4 Other hyperlipidaemia	0.323	0.677	0.000
E65 Localised adiposity	0.323	0.677	0.000
E78.1 Pure hyperglyceridaemia	0.323	0.677	0.000
Z52 Donors of organs and tissues	0.323	0.677	0.000
E78.6 Lipoprotein deficiency	0.323	0.677	0.000
E78.3 Hyperchylomicronaemia	0.322	0.677	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.322	0.678	0.000
E11.1 With ketoacidosis	0.322	0.678	0.000
E11.6 With other specified complications	0.322	0.678	0.000
E67 Other hyperalimentation	0.322	0.678	0.000
E68 Sequelae of hyperalimentation	0.322	0.678	0.000
E11.8 With unspecified complications	0.322	0.678	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.321	0.678	0.000
E07 Other disorders of thyroid	0.321	0.679	0.000
E11.7 With multiple complications	0.321	0.679	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.321	0.679	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.320	0.679	0.000
Chapter XI Diseases of the digestive system	0.320	0.679	0.000
E06 Thyroiditis	0.320	0.680	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.320	0.680	0.000
C60-C63 Malignant neoplasms of male genital organs	0.320	0.680	0.000
M75 Shoulder lesions	0.320	0.680	0.000
I24.1 Dressler's syndrome	0.319	0.681	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.319	0.681	0.000
I05 Rheumatic mitral valve diseases	0.319	0.681	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.319	0.681	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.319	0.681	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.319	0.681	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.319	0.681	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.318	0.681	0.000
I07 Rheumatic tricuspid valve diseases	0.318	0.681	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.318	0.682	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.318	0.682	0.000
G20-G26 Extrapyramidal and movement disorders	0.318	0.682	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.318	0.682	0.000
E00 Congenital iodine-deficiency syndrome	0.318	0.682	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.317	0.682	0.000
F30-F39 Mood [affective] disorders	0.317	0.682	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.317	0.683	0.000
O80-O84 Delivery	0.317	0.683	0.000
I61 Intracerebral haemorrhage	0.317	0.683	0.000
I06 Rheumatic aortic valve diseases	0.316	0.684	0.000
I09 Other rheumatic heart diseases	0.316	0.684	0.000
J22 Unspecified acute lower respiratory infection	0.316	0.684	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.316	0.684	0.000
Z53.0 Procedure not carried out because of contraindication	0.316	0.684	0.000
Z47 Other orthopaedic follow-up care	0.315	0.685	0.000
J45 Asthma	0.315	0.685	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.315	0.685	0.000
I22.8 Subsequent myocardial infarction of other sites	0.315	0.685	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.314	0.685	0.000
J90 Pleural effusion, not elsewhere classified	0.314	0.686	0.000
I08 Multiple valve diseases	0.313	0.686	0.000
I00 Rheumatic fever without mention of heart involvement	0.313	0.687	0.000
I02 Rheumatic chorea	0.313	0.687	0.000
I01 Rheumatic fever with heart involvement	0.313	0.687	0.000
I62 Other nontraumatic intracranial haemorrhage	0.313	0.687	0.000
M23 Internal derangement of knee	0.312	0.688	0.000
G40-G47 Episodic and paroxysmal disorders	0.311	0.689	0.000
Z92 Personal history of medical treatment	0.311	0.689	0.000
M20 Acquired deformities of fingers and toes	0.310	0.690	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.310	0.690	0.000
L82 Seborrhoeic keratosis	0.309	0.691	0.000
G30-G32 Other degenerative diseases of the nervous system	0.309	0.691	0.000
E11.0 With coma	0.309	0.691	0.000
I23.8 Other current complications following acute myocardial infarction	0.308	0.692	0.000
Z51.2 Other chemotherapy	0.308	0.692	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.308	0.692	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.308	0.692	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.308	0.692	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.308	0.692	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.308	0.692	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.308	0.692	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.308	0.692	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.308	0.692	0.000
O00-O08 Pregnancy with abortive outcome	0.308	0.692	0.000
I50.1 Left ventricular failure	0.307	0.693	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.307	0.693	0.000
P10-P15 Birth trauma	0.306	0.694	0.000
P90-P96 Other disorders originating in the perinatal period	0.306	0.694	0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.306	0.694	0.000
P75-P78 Digestive system disorders of fetus and newborn	0.306	0.694	0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.306	0.694	0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.306	0.694	0.000
P35-P39 Infections specific to the perinatal period	0.306	0.694	0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.306	0.694	0.000
P05-P08 Disorders related to length of gestation and fetal growth	0.306	0.694	0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.306	0.694	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.306	0.694	0.000
G70-G73 Diseases of myoneural junction and muscle	0.306	0.694	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.306	0.694	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.304	0.695	0.000
L81 Other disorders of pigmentation	0.304	0.696	0.000
I12.0 Hypertensive renal disease with renal failure	0.304	0.696	0.000
L89 Decubitus ulcer	0.304	0.696	0.000
E23 Hypofunction and other disorders of pituitary gland	0.303	0.696	0.000
D55-D59 Haemolytic anaemias	0.303	0.697	0.000
L85 Other epidermal thickening	0.303	0.697	0.000
E22 Hyperfunction of pituitary gland	0.303	0.697	0.000
M50-M54 Other dorsopathies	0.302	0.697	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.302	0.698	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.302	0.698	0.000
I12.9 Hypertensive renal disease without renal failure	0.302	0.698	0.000
I21.9 Acute myocardial infarction, unspecified	0.301	0.698	0.000
E34 Other endocrine disorders	0.301	0.699	0.000
E29 Testicular dysfunction	0.301	0.699	0.000
E24 Cushing's syndrome	0.301	0.699	0.000
M06 Other rheumatoid arthritis	0.301	0.699	0.000
G90-G99 Other disorders of the nervous system	0.301	0.699	0.000
L84 Corns and callosities	0.301	0.699	0.000
E26 Hyperaldosteronism	0.301	0.699	0.000
E20 Hypoparathyroidism	0.300	0.699	0.000
N20-N23 Urolithiasis	0.300	0.700	0.000
E25 Adrenogenital disorders	0.300	0.700	0.000
E32 Diseases of thymus	0.300	0.700	0.000
E31 Polyglandular dysfunction	0.300	0.700	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.300	0.700	0.000
E30 Disorders of puberty, not elsewhere classified	0.300	0.700	0.000
Z46 Fitting and adjustment of other devices	0.300	0.700	0.000
M17.9 Gonarthrosis, unspecified	0.299	0.700	0.000
Q00-Q07 Congenital malformations of the nervous system	0.299	0.700	0.000
M16.9 Coxarthrosis, unspecified	0.299	0.700	0.000
I73.9 Peripheral vascular disease, unspecified	0.299	0.701	0.000
L94 Other localised connective tissue disorders	0.298	0.701	0.000
L83 Acanthosis nigricans	0.298	0.701	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.298	0.701	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.298	0.701	0.000
L93 Lupus erythematosus	0.298	0.702	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.298	0.702	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.298	0.702	0.000
L80 Vitiligo	0.298	0.702	0.000
L91 Hypertrophic disorders of skin	0.298	0.702	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.298	0.702	0.000
Q35-Q37 Cleft lip and cleft palate	0.298	0.702	0.000
L88 Pyoderma gangrenosum	0.298	0.702	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.297	0.703	0.000
L87 Transepidermal elimination disorders	0.297	0.703	0.000
L86 Keratoderma in diseases classified elsewhere	0.297	0.703	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.297	0.703	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.297	0.703	0.000
J44 Other chronic obstructive pulmonary disease	0.297	0.703	0.000
R30-R39 Symptoms and signs involving the urinary system	0.297	0.703	0.000
J43 Emphysema	0.297	0.703	0.000
I15.1 Hypertension secondary to other renal disorders	0.296	0.704	0.000
E27 Other disorders of adrenal gland	0.296	0.704	0.000
L90 Atrophic disorders of skin	0.296	0.704	0.000
E46 Unspecified protein-energy malnutrition	0.296	0.704	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.296	0.704	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.295	0.704	0.001
Q38-Q45 Other congenital malformations of the digestive system	0.296	0.704	0.000
E53 Deficiency of other B group vitamins	0.296	0.704	0.000
Q80-Q89 Other congenital malformations	0.296	0.704	0.000
I15.9 Seconday hypertension, unspecified	0.295	0.704	0.000
M10 Gout	0.295	0.704	0.000
D60-D64 Aplastic and other anaemias	0.295	0.705	0.000
I15.0 Renovascular hypertension	0.295	0.705	0.000
I15.8 Other secondary hypertension	0.295	0.705	0.000
I15.2 Hypertension secondary to endocrine disorders	0.295	0.705	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.294	0.706	0.000
E45 Retarded development following protein-energy malnutrition	0.294	0.706	0.000
E43 Unspecified severe protein-energy malnutrition	0.294	0.706	0.000
E42 Marasmic kwashiorkor	0.294	0.706	0.000
E41 Nutritional marasmus	0.294	0.706	0.000
E40 Kwashiorkor	0.294	0.706	0.000
C44 Other malignant neoplasms of skin	0.294	0.706	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.294	0.706	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.294	0.706	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.294	0.706	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.294	0.706	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.294	0.706	0.000
E28 Ovarian dysfunction	0.294	0.706	0.000
C64-C68 Malignant neoplasms of urinary tract	0.293	0.706	0.000
Y43 Primarily systemic agents	0.293	0.706	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.293	0.706	0.000
L03 Cellulitis	0.292	0.707	0.000
Z53.8 Procedure not carried out for other reasons	0.292	0.708	0.000
M35 Other systemic involvement of connective tissue	0.292	0.708	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.292	0.708	0.000
D80-D89 Certain disorders involving the immune mechanism	0.291	0.709	0.000
Z51.8 Other specified medical care	0.291	0.709	0.000
Z53.9 Procedure not carried out, unspecified reason	0.290	0.710	0.000
M31 Other necrotising vasculopathies	0.290	0.710	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.290	0.710	0.000
Q50-Q56 Congenital malformations of genital organs	0.290	0.710	0.000
E58 Dietary calcium deficiency	0.290	0.710	0.000
E51 Thiamine deficiency	0.290	0.710	0.000
E56 Other vitamin deficiencies	0.290	0.710	0.000
E54 Ascorbic acid deficiency	0.290	0.710	0.000
E63 Other nutritional deficiencies	0.290	0.710	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.290	0.710	0.000
E50 Vitamin A deficiency	0.290	0.710	0.000
E60 Dietary zinc deficiency	0.290	0.710	0.000
E59 Dietary selenium deficiency	0.290	0.710	0.000
E52 Niacin deficiency [pellagra]	0.290	0.710	0.000
J40 Bronchitis, not specified as acute or chronic	0.289	0.710	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.289	0.711	0.000
J93 Pneumothorax	0.289	0.711	0.000
J92 Pleural plaque	0.288	0.711	0.000
E66.9 Obesity, unspecified	0.288	0.711	0.000
Z13 Special screening examination for other diseases and disorders	0.288	0.711	0.000
L08 Other local infections of skin and subcutaneous tissue	0.288	0.712	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.288	0.712	0.000
D50-D53 Nutritional anaemias	0.288	0.712	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.288	0.712	0.000
M24 Other specific joint derangements	0.287	0.712	0.000
M34 Systemic sclerosis	0.287	0.712	0.000
M05 Seropositive rheumatoid arthritis	0.287	0.713	0.000
I67 Other cerebrovascular diseases	0.287	0.713	0.000
Z51.0 Radiotherapy session	0.287	0.713	0.000
E15 Nondiabetic hypoglycaemic coma	0.287	0.713	0.000
M07 Psoriatic and enteropathic arthropathies	0.287	0.713	0.000
Z60 Problems related to social environment	0.286	0.713	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.286	0.714	0.000
M33 Dermatopolymyositis	0.286	0.714	0.000
M30 Polyarteritis nodosa and related conditions	0.286	0.714	0.000
I73.0 Raynaud's syndrome	0.286	0.714	0.000
M32 Systemic lupus erythematosus	0.286	0.714	0.000
Q60-Q64 Congenital malformations of the urinary system	0.285	0.714	0.000
J46 Status asthmaticus	0.285	0.714	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.285	0.714	0.000
J30-J39 Other diseases of upper respiratory tract	0.285	0.714	0.000
C43 Malignant melanoma of skin	0.285	0.715	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.285	0.715	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations