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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35650677
log Bayes Factor = 25.285
Chromosome 6   position 22,078,097  (GRCh37) Explore rs35650677 on Ensembl!
Variant rs35650677 is part of Cluster X0161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
M75 Shoulder lesions
0.998 0.002 0.000
M20-M25 Other joint disorders
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.994 0.006 0.000
Z51 Other medical care
0.990 0.010 0.000
M75.4 Impingement syndrome of shoulder
0.990 0.010 0.000
C15-C26 Malignant neoplasms of digestive organs
0.988 0.012 0.000
M23 Internal derangement of knee
0.987 0.013 0.000
Chapter XI Diseases of the digestive system
0.985 0.015 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.984 0.016 0.000
M50-M54 Other dorsopathies
0.983 0.017 0.000
R50-R69 General symptoms and signs
0.982 0.018 0.000
Z93 Artificial opening status
0.977 0.023 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.974 0.026 0.000
Z53.0 Procedure not carried out because of contraindication
0.973 0.027 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.973 0.027 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.969 0.031 0.000
Chapter XX External causes of morbidity and mortality
0.969 0.031 0.000
M25 Other joint disorders, not elsewhere classified
0.968 0.032 0.000
Z51.2 Other chemotherapy
0.967 0.033 0.000
N30-N39 Other diseases of urinary system
0.967 0.033 0.000
Chapter VII Diseases of the eye and adnexa
0.964 0.036 0.000
M54 Dorsalgia
0.963 0.037 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.961 0.039 0.000
N39 Other disorders of urinary system
0.961 0.039 0.000
M05-M14 Inflammatory polyarthropathies
0.960 0.040 0.000
Chapter V Mental and behavioural disorders
0.955 0.045 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.954 0.046 0.000
K50-K52 Noninfective enteritis and colitis
0.953 0.047 0.000
M45-M49 Spondylopathies
0.953 0.047 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.951 0.049 0.000
R50 Fever of unknown origin
0.951 0.049 0.000
M23.3 Other meniscus derangements
0.948 0.052 0.000
N39.0 Urinary tract infection, site not specified
0.946 0.054 0.000
Z51.5 Palliative care
0.945 0.055 0.000
Z98 Other postsurgical states
0.944 0.056 0.000
Z96 Presence of other functional implants
0.943 0.057 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.940 0.060 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.938 0.062 0.000
C79 Secondary malignant neoplasm of other sites
0.934 0.066 0.000
M75.0 Adhesive capsulitis of shoulder
0.931 0.069 0.000
M10 Gout
0.930 0.070 0.000
R06 Abnormalities of breathing
0.928 0.072 0.000
N10-N16 Renal tubulo-interstitial diseases
0.927 0.073 0.000
R50.9 Fever, unspecified
0.927 0.073 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.926 0.074 0.000
K50 Crohn's disease [regional enteritis]
0.921 0.079 0.000
K35-K38 Diseases of appendix
0.921 0.079 0.000
Z43 Attention to artificial openings
0.921 0.079 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.920 0.080 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.918 0.082 0.000
C18 Malignant neoplasm of colon
0.918 0.082 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.915 0.085 0.000
Z45 Adjustment and management of implanted device
0.913 0.087 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.910 0.090 0.000
M54.2 Cervicalgia
0.910 0.090 0.000
Z87 Personal history of other diseases and conditions
0.910 0.090 0.000
M10.9 Gout, unspecified
0.908 0.092 0.000
K70-K77 Diseases of liver
0.904 0.096 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.904 0.096 0.000
R69 Unknown and unspecified causes of morbidity
0.904 0.096 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.903 0.097 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.903 0.097 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.903 0.097 0.000
Chapter I Certain infectious and parasitic diseases
0.897 0.103 0.000
C15 Malignant neoplasm of oesophagus
0.896 0.104 0.000
M54.5 Low back pain
0.892 0.108 0.000
M25.5 Pain in joint
0.890 0.110 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.888 0.112 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.888 0.112 0.000
C78.7 Secondary malignant neoplasm of liver
0.887 0.113 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.887 0.113 0.000
D00-D09 In situ neoplasms
0.886 0.114 0.000
Z93.3 Colostomy status
0.885 0.115 0.000
M10.99 Gout, unspecified (Site unspecified)
0.883 0.117 0.000
Z98.1 Arthrodesis status
0.882 0.118 0.000
M54.22 Cervicalgia (Cervical region)
0.872 0.128 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.868 0.132 0.000
D10-D36 Benign neoplasms
0.867 0.133 0.000
M47 Spondylosis
0.866 0.134 0.000
L90 Atrophic disorders of skin
0.865 0.135 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.863 0.137 0.000
N72 Inflammatory disease of cervix uteri
0.862 0.138 0.000
R26 Abnormalities of gait and mobility
0.862 0.138 0.000
N39.3 Stress incontinence
0.859 0.141 0.000
R59 Enlarged lymph nodes
0.856 0.144 0.000
N13 Obstructive and reflux uropathy
0.855 0.145 0.000
M75.5 Bursitis of shoulder
0.851 0.149 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.851 0.149 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.850 0.150 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.850 0.150 0.000
R06.5 Mouth breathing
0.849 0.151 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.849 0.151 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.848 0.152 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.848 0.152 0.000
Z93.2 Ileostomy status
0.848 0.152 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.846 0.154 0.000
H53-H54 Visual disturbances and blindness
0.846 0.154 0.000
R06.0 Dyspnoea
0.845 0.155 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.844 0.156 0.000
K04 Diseases of pulp and periapical tissues
0.843 0.157 0.000
K50.9 Crohn's disease, unspecified
0.843 0.157 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.839 0.161 0.000
T43.2 Other and unspecified antidepressants
0.837 0.163 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.837 0.163 0.000
Y86 Sequelae of other accidents
0.836 0.164 0.000
D22 Melanocytic naevi
0.836 0.164 0.000
Z96.8 Presence of other specified functional implants
0.836 0.164 0.000
Z90.5 Acquired absence of kidney
0.835 0.165 0.000
Z96.1 Presence of intraocular lens
0.835 0.165 0.000
G20-G26 Extrapyramidal and movement disorders
0.832 0.168 0.000
C18.7 Sigmoid colon
0.831 0.169 0.000
N95 Menopausal and other perimenopausal disorders
0.831 0.169 0.000
Z45.2 Adjustment and management of vascular access device
0.830 0.170 0.000
M54.56 Low back pain (Lumbar region)
0.829 0.171 0.000
K37 Unspecified appendicitis
0.826 0.174 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.824 0.176 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.824 0.176 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.824 0.176 0.000
M48 Other spondylopathies
0.819 0.181 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.819 0.181 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.819 0.181 0.000
B95-B98 Bacterial, viral and other infectious agents
0.817 0.183 0.000
M25.8 Other specified joint disorders
0.816 0.183 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.812 0.188 0.000
R51 Headache
0.812 0.188 0.000
S00-S09 Injuries to the head
0.811 0.189 0.000
M86-M90 Other osteopathies
0.811 0.189 0.000
S80-S89 Injuries to the knee and lower leg
0.810 0.190 0.000
Z93.0 Tracheostomy status
0.809 0.191 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.809 0.191 0.000
Z53.8 Procedure not carried out for other reasons
0.808 0.192 0.000
L60-L75 Disorders of skin appendages
0.806 0.194 0.000
Z98.0 Intestinal bypass and anastomosis status
0.805 0.195 0.000
D03 Melanoma in situ
0.805 0.195 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.804 0.196 0.000
H02 Other disorders of eyelid
0.804 0.196 0.000
K13 Other diseases of lip and oral mucosa
0.802 0.198 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.802 0.198 0.000
Z92 Personal history of medical treatment
0.802 0.198 0.000
C78.0 Secondary malignant neoplasm of lung
0.801 0.199 0.000
M25.50 Pain in joint (Multiple sites)
0.801 0.199 0.000
M21 Other acquired deformities of limbs
0.800 0.200 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.800 0.200 0.000
C51-C58 Malignant neoplasms of female genital organs
0.799 0.201 0.000
C15.9 Oesophagus, unspecified
0.799 0.201 0.000
R00 Abnormalities of heart beat
0.798 0.202 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.797 0.203 0.000
K35 Acute appendicitis
0.795 0.205 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.795 0.205 0.000
L90.5 Scar conditions and fibrosis of skin
0.795 0.205 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.794 0.206 0.000
R07 Pain in throat and chest
0.792 0.208 0.000
N88 Other noninflammatory disorders of cervix uteri
0.791 0.209 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.791 0.209 0.000
Z90.1 Acquired absence of breast(s)
0.790 0.210 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.790 0.210 0.000
M25.4 Effusion of joint
0.790 0.210 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.788 0.212 0.000
S40-S49 Injuries to the shoulder and upper arm
0.788 0.212 0.000
M24 Other specific joint derangements
0.788 0.212 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.788 0.212 0.000
Z93.5 Cystostomy status
0.787 0.213 0.000
S50-S59 Injuries to the elbow and forearm
0.786 0.214 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.785 0.215 0.000
Z90.0 Acquired absence of part of head and neck
0.784 0.216 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.783 0.217 0.000
K50.0 Crohn's disease of small intestine
0.783 0.217 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.783 0.217 0.000
Z43.3 Attention to colostomy
0.782 0.218 0.000
L81 Other disorders of pigmentation
0.782 0.218 0.000
N95.2 Postmenopausal atrophic vaginitis
0.782 0.218 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.780 0.219 0.000
Z96.0 Presence of urogenital implants
0.780 0.220 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.780 0.220 0.000
C21 Malignant neoplasm of anus and anal canal
0.779 0.221 0.000
M47.9 Spondylosis, unspecified
0.779 0.221 0.000
Chapter XXII Codes for special purposes
0.778 0.222 0.000
M65-M68 Disorders of synovium and tendon
0.777 0.223 0.000
Chapter X Diseases of the respiratory system
0.777 0.223 0.000
K51 Ulcerative colitis
0.777 0.223 0.000
K04.5 Chronic apical periodontitis
0.775 0.225 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.775 0.225 0.000
M50 Cervical disk disorders
0.773 0.227 0.000
M75.1 Rotator cuff syndrome
0.773 0.227 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.772 0.227 0.000
Z87.0 Personal history of diseases of the respiratory system
0.770 0.230 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.769 0.231 0.000
M80-M85 Disorders of bone density and structure
0.768 0.232 0.000
N13.3 Other and unspecified hydronephrosis
0.768 0.232 0.000
M54.1 Radiculopathy
0.768 0.232 0.000
M22 Disorders of patella
0.767 0.233 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.767 0.233 0.000
D22.5 Melanocytic naevi of trunk
0.767 0.233 0.000
H43-H45 Disorders of vitreous body and globe
0.767 0.233 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.767 0.233 0.000
K75 Other inflammatory liver diseases
0.765 0.235 0.000
R27 Other lack of coordination
0.764 0.236 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.763 0.237 0.000
M40-M43 Deforming dorsopathies
0.763 0.237 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.761 0.239 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.761 0.239 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.760 0.240 0.000
C78.2 Secondary malignant neoplasm of pleura
0.760 0.240 0.000
M51 Other intervertebral disk disorders
0.760 0.240 0.000
S60-S69 Injuries to the wrist and hand
0.759 0.241 0.000
R22.0 Localised swelling, mass and lump, head
0.759 0.241 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.759 0.241 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.759 0.241 0.000
Z51.0 Radiotherapy session
0.759 0.241 0.000
M79.6 Pain in limb
0.757 0.243 0.000
R59.0 Localised enlarged lymph nodes
0.757 0.243 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.757 0.243 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.757 0.243 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.756 0.244 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.756 0.244 0.000
M25.57 Pain in joint (Ankle and foot)
0.756 0.244 0.000
R07.4 Chest pain, unspecified
0.755 0.245 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.754 0.246 0.000
F17.1 Harmful use
0.754 0.246 0.000
G70-G73 Diseases of myoneural junction and muscle
0.753 0.247 0.000
N76 Other inflammation of vagina and vulva
0.753 0.247 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.753 0.247 0.000
K50.8 Other Crohn's disease
0.753 0.247 0.000
Z43.2 Attention to ileostomy
0.753 0.247 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.752 0.247 0.000
Z97 Presence of other devices
0.752 0.248 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.752 0.248 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.751 0.248 0.000
M23.8 Other internal derangements of knee
0.751 0.249 0.000
Z51.3 Blood transfusion without reported diagnosis
0.751 0.249 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.751 0.249 0.000
H53 Visual disturbances
0.751 0.249 0.000
C20 Malignant neoplasm of rectum
0.750 0.250 0.000
C80 Malignant neoplasm without specification of site
0.747 0.253 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.747 0.253 0.000
N39.8 Other specified disorders of urinary system
0.747 0.253 0.000
R00.0 Tachycardia, unspecified
0.747 0.253 0.000
C25 Malignant neoplasm of pancreas
0.746 0.254 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.746 0.254 0.000
N73 Other female pelvic inflammatory diseases
0.744 0.256 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.744 0.256 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.743 0.257 0.000
R06.6 Hiccough
0.743 0.257 0.000
M77 Other enthesopathies
0.742 0.258 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.741 0.259 0.000
Chapter VIII Diseases of the ear and mastoid process
0.741 0.259 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.739 0.260 0.000
M79.5 Residual foreign body in soft tissue
0.739 0.261 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.739 0.261 0.000
C18.4 Transverse colon
0.738 0.262 0.000
Z45.8 Adjustment and management of other implanted devices
0.738 0.262 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.738 0.262 0.000
M54.59 Low back pain (Site unspecified)
0.738 0.262 0.000
M07 Psoriatic and enteropathic arthropathies
0.737 0.263 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.736 0.264 0.000
L84 Corns and callosities
0.736 0.264 0.000
N95.0 Postmenopausal bleeding
0.736 0.264 0.000
N00-N08 Glomerular diseases
0.736 0.264 0.000
R29.6 Tendency to fall, not elsewhere classified
0.735 0.265 0.000
K12 Stomatitis and related lesions
0.733 0.266 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.733 0.267 0.000
R25 Abnormal involuntary movements
0.733 0.267 0.000
M25.7 Osteophyte
0.732 0.268 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.731 0.269 0.000
K76 Other diseases of liver
0.731 0.269 0.000
H55-H59 Other disorders of eye and adnexa
0.731 0.269 0.000
M23.4 Loose body in knee
0.729 0.271 0.000
R56 Convulsions, not elsewhere classified
0.729 0.271 0.000
H50 Other strabismus
0.729 0.271 0.000
Z93.6 Other artificial openings of urinary tract status
0.729 0.271 0.000
D11 Benign neoplasm of major salivary glands
0.728 0.272 0.000
G61 Inflammatory polyneuropathy
0.728 0.272 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.728 0.272 0.000
H25-H28 Disorders of lens
0.727 0.273 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.726 0.274 0.000
C91 Lymphoid leukaemia
0.726 0.274 0.000
C15.5 Lower third of oesophagus
0.725 0.275 0.000
C16 Malignant neoplasm of stomach
0.724 0.276 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.724 0.276 0.000
Y85 Sequelae of transport accidents
0.723 0.276 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.723 0.277 0.000
F41 Other anxiety disorders
0.723 0.277 0.000
M48.0 Spinal stenosis
0.723 0.277 0.000
K80 Cholelithiasis
0.722 0.278 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.721 0.279 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.720 0.280 0.000
M46 Other inflammatory spondylopathies
0.720 0.280 0.000
G20 Parkinson's disease
0.720 0.280 0.000
T40.2 Other opioids
0.720 0.280 0.000
M06 Other rheumatoid arthritis
0.719 0.281 0.000
G62 Other polyneuropathies
0.719 0.281 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.717 0.283 0.000
L85 Other epidermal thickening
0.717 0.283 0.000
X60-X84 Intentional self-harm
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.283 0.000
M71 Other bursopathies
0.716 0.283 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.716 0.283 0.000
Z54 Convalescence
0.716 0.283 0.000
Z52 Donors of organs and tissues
0.716 0.283 0.000
Z49 Care involving dialysis
0.716 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.283 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
M75.8 Other shoulder lesions
0.716 0.284 0.000
M75.9 Shoulder lesion, unspecified
0.716 0.284 0.000
M75.2 Bicipital tendinitis
0.716 0.284 0.000
M25.53 Pain in joint (Forearm)
0.715 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M34 Systemic sclerosis
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
N39.4 Other specified urinary incontinence
0.714 0.286 0.000
Z94 Transplanted organ and tissue status
0.714 0.286 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.714 0.286 0.000
K70 Alcoholic liver disease
0.714 0.286 0.000
L90.0 Lichen sclerosus et atrophicus
0.713 0.287 0.000
C83.0 Small cell (diffuse)
0.713 0.287 0.000
M11 Other crystal arthropathies
0.713 0.287 0.000
C43 Malignant melanoma of skin
0.713 0.287 0.000
J00-J06 Acute upper respiratory infections
0.713 0.287 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.713 0.287 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.713 0.287 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.712 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.712 0.288 0.000
W20-W49 Exposure to inanimate mechanical forces
0.712 0.288 0.000
D04 Carcinoma in situ of skin
0.712 0.288 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.711 0.289 0.000
K65-K67 Diseases of peritoneum
0.711 0.289 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.711 0.289 0.000
K05 Gingivitis and periodontal diseases
0.711 0.289 0.000
C18.9 Colon, unspecified
0.710 0.290 0.000
N25-N29 Other disorders of kidney and ureter
0.710 0.290 0.000
Z51.9 Medical care, unspecified
0.710 0.290 0.000
Z51.6 Desensitisation to allergens
0.710 0.290 0.000
V10-V19 Pedal cyclist injured in transport accident
0.709 0.291 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.709 0.291 0.000
M45 Ankylosing spondylitis
0.709 0.291 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.708 0.291 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.708 0.291 0.000
C17 Malignant neoplasm of small intestine
0.708 0.291 0.000
C23 Malignant neoplasm of gallbladder
0.708 0.291 0.000
Z88.0 Personal history of allergy to penicillin
0.708 0.292 0.000
M23.9 Internal derangement of knee, unspecified
0.707 0.293 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.707 0.293 0.000
M23.5 Chronic instability of knee
0.707 0.293 0.000
M23.1 Discoid meniscus (congenital)
0.707 0.293 0.000
M23.0 Cystic meniscus
0.707 0.293 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.707 0.293 0.000
Z93.1 Gastrostomy status
0.707 0.293 0.000
L89 Decubitus ulcer
0.707 0.293 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.707 0.293 0.000
G50 Disorders of trigeminal nerve
0.707 0.293 0.000
Z53.9 Procedure not carried out, unspecified reason
0.707 0.293 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.706 0.293 0.000
H02.4 Ptosis of eyelid
0.706 0.294 0.000
Z90.3 Acquired absence of part of stomach
0.706 0.294 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.706 0.294 0.000
Y57 Other and unspecified drugs and medicaments
0.706 0.294 0.000
R54 Senility
0.706 0.294 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.705 0.295 0.000
F40 Phobic anxiety disorders
0.705 0.295 0.000
S09 Other and unspecified injuries of head
0.705 0.295 0.000
M53 Other dorsopathies, not elsewhere classified
0.705 0.295 0.000
R94 Abnormal results of function studies
0.705 0.295 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.705 0.295 0.000
N71 Inflammatory disease of uterus, except cervix
0.704 0.295 0.000
B25-B34 Other viral diseases
0.704 0.296 0.000
R68 Other general symptoms and signs
0.704 0.296 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.704 0.296 0.000
R62 Lack of expected normal physiological development
0.704 0.296 0.000
R57 Shock, not elsewhere classified
0.704 0.296 0.000
R64 Cachexia
0.704 0.296 0.000
R58 Haemorrhage, not elsewhere classified
0.704 0.296 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.704 0.296 0.000
F45 Somatoform disorders
0.704 0.296 0.000
L08 Other local infections of skin and subcutaneous tissue
0.704 0.296 0.000
L05 Pilonidal cyst
0.703 0.297 0.000
Z87.8 Personal history of other specified conditions
0.701 0.299 0.000
N83.2 Other and unspecified ovarian cysts
0.701 0.299 0.000
Z93.9 Artificial opening status, unspecified
0.700 0.300 0.000
Z93.8 Other artificial opening status
0.700 0.300 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.700 0.300 0.000
Y43 Primarily systemic agents
0.700 0.300 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.700 0.300 0.000
L40-L45 Papulosquamous disorders
0.699 0.301 0.000
M72 Fibroblastic disorders
0.699 0.301 0.000
R50.0 Fever with chills
0.698 0.301 0.000
L10-L14 Bullous disorders
0.698 0.302 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.698 0.302 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.698 0.302 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.698 0.302 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.698 0.302 0.000
Y52 Agents primarily affecting the cardiovascular system
0.697 0.303 0.000
C54 Malignant neoplasm of corpus uteri
0.697 0.303 0.000
H02.9 Disorder of eyelid, unspecified
0.697 0.303 0.000
K50.1 Crohn's disease of large intestine
0.696 0.303 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.696 0.304 0.000
M79.8 Other specified soft tissue disorders
0.695 0.305 0.000
V20-V29 Motorcycle rider injured in transport accident
0.695 0.305 0.000
Z41 Procedures for purposes other than remedying health state
0.695 0.305 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.695 0.305 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.305 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.695 0.305 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.695 0.305 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.695 0.305 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.695 0.305 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.695 0.305 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
T36 Poisoning by systemic antibiotics
0.695 0.305 0.000
R06.8 Other and unspecified abnormalities of breathing
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.695 0.305 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.305 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V40-V49 Car occupant injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.305 0.000
M25.9 Joint disorder, unspecified
0.694 0.306 0.000
M25.3 Other instability of joint
0.694 0.306 0.000
M25.2 Flail joint
0.694 0.306 0.000
M25.1 Fistula of joint
0.694 0.306 0.000
M25.0 Haemarthrosis
0.694 0.306 0.000
N75 Diseases of Bartholin's gland
0.694 0.306 0.000
T91 Sequelae of injuries of neck and trunk
0.694 0.306 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.693 0.307 0.000
N37 Urethral disorders in diseases classified elsewhere
0.693 0.307 0.000
N36 Other disorders of urethra
0.693 0.307 0.000
N34 Urethritis and urethral syndrome
0.693 0.307 0.000
N33 Bladder disorders in diseases classified elsewhere
0.693 0.307 0.000
K74 Fibrosis and cirrhosis of liver
0.693 0.307 0.000
Z83 Family history of other specific disorders
0.692 0.308 0.000
B35-B49 Mycoses
0.691 0.309 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.691 0.309 0.000
S70-S79 Injuries to the hip and thigh
0.690 0.309 0.000
M54.8 Other dorsalgia
0.690 0.310 0.000
M54.6 Pain in thoracic spine
0.690 0.310 0.000
M54.4 Lumbago with sciatica
0.690 0.310 0.000
M54.0 Panniculitis affecting regions of neck and back
0.690 0.310 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.690 0.310 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.690 0.310 0.000
T87 Complications peculiar to reattachment and amputation
0.689 0.311 0.000
T86 Failure and rejection of transplanted organs and tissues
0.689 0.311 0.000
N39.2 Orthostatic proteinuria, unspecified
0.689 0.311 0.000
N39.1 Persistent proteinuria, unspecified
0.689 0.311 0.000
D18 Haemangioma and lymphangioma, any site
0.689 0.311 0.000
R52 Pain, not elsewhere classified
0.689 0.311 0.000
H10-H13 Disorders of conjunctiva
0.688 0.311 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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