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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3731544
log Bayes Factor = 6.92182
Chromosome 3   position 48,207,997  (GRCh37) Explore rs3731544 on Ensembl!
Variant rs3731544 is part of Cluster X0114

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
0.999 0.001 0.000
I25.1 Atherosclerotic heart disease
0.999 0.001 0.000
I25.2 Old myocardial infarction
0.991 0.009 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.984 0.016 0.000
I21 Acute myocardial infarction
0.977 0.023 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.952 0.048 0.000
I20.8 Other forms of angina pectoris
0.923 0.077 0.000
I20.1 Angina pectoris with documented spasm
0.909 0.091 0.000
I22 Subsequent myocardial infarction
0.879 0.121 0.000
I20.0 Unstable angina
0.866 0.134 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.852 0.148 0.000
I21.9 Acute myocardial infarction, unspecified
0.833 0.167 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.784 0.216 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.772 0.228 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.750 0.250 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.701 0.299 0.000
I25.3 Aneurysm of heart
0.686 0.314 0.000
I22.8 Subsequent myocardial infarction of other sites
0.683 0.317 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.671 0.329 0.000
I25.5 Ischaemic cardiomyopathy
0.649 0.351 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.634 0.366 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.632 0.368 0.000
I95 Hypotension
0.610 0.390 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.604 0.396 0.000
Chapter IX Diseases of the circulatory system
0.603 0.397 0.000
I95.9 Hypotension, unspecified
0.599 0.401 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.586 0.414 0.000
I95.2 Hypotension due to drugs
0.551 0.449 0.000
I95.1 Orthostatic hypotension
0.549 0.451 0.000
I21.4 Acute subendocardial myocardial infarction
0.523 0.477 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.517 0.483 0.000
I23.8 Other current complications following acute myocardial infarction
0.514 0.486 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.514 0.486 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.514 0.486 0.000
I10-I15 Hypertensive diseases
0.505 0.495 0.000
I95.8 Other hypotension
0.486 0.514 0.000
I26 Pulmonary embolism
0.477 0.523 0.000
I10 Essential (primary) hypertension
0.464 0.536 0.000
I24 Other acute ischaemic heart diseases
0.455 0.545 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.446 0.554 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.439 0.561 0.000
I00-I02 Acute rheumatic fever
0.432 0.568 0.000
I95.0 Idiopathic hypotension
0.426 0.574 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.414 0.586 0.000
I99 Other and unspecified disorders of circulatory system
0.386 0.614 0.000
I05-I09 Chronic rheumatic heart diseases
0.379 0.621 0.000
I28 Other diseases of pulmonary vessels
0.371 0.629 0.000
I15 Secondary hypertension
0.364 0.635 0.000
I13 Hypertensive heart and renal disease
0.362 0.638 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.350 0.650 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.331 0.669 0.000
I24.1 Dressler's syndrome
0.326 0.673 0.000
I12 Hypertensive renal disease
0.323 0.677 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.321 0.679 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.319 0.681 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.315 0.685 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.315 0.685 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.315 0.685 0.000
I98.0 Cardiovascular syphilis
0.315 0.685 0.000
I02 Rheumatic chorea
0.310 0.690 0.000
I01 Rheumatic fever with heart involvement
0.310 0.690 0.000
I00 Rheumatic fever without mention of heart involvement
0.310 0.690 0.000
I11 Hypertensive heart disease
0.309 0.691 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.297 0.703 0.000
I97.0 Postcardiotomy syndrome
0.297 0.703 0.000
I07 Rheumatic tricuspid valve diseases
0.297 0.703 0.000
I24.8 Other forms of acute ischaemic heart disease
0.296 0.704 0.000
I27 Other pulmonary heart diseases
0.296 0.704 0.000
I09 Other rheumatic heart diseases
0.287 0.713 0.000
I97.1 Other functional disturbances following cardiac surgery
0.275 0.725 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.274 0.726 0.000
I06 Rheumatic aortic valve diseases
0.272 0.728 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.266 0.734 0.000
I28.8 Other specified diseases of pulmonary vessels
0.266 0.734 0.000
I28.1 Aneurysm of pulmonary artery
0.266 0.734 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.266 0.734 0.000
I15.1 Hypertension secondary to other renal disorders
0.264 0.736 0.000
I15.9 Seconday hypertension, unspecified
0.261 0.738 0.000
I15.8 Other secondary hypertension
0.261 0.738 0.000
I15.2 Hypertension secondary to endocrine disorders
0.261 0.738 0.000
I15.0 Renovascular hypertension
0.261 0.738 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.260 0.740 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.260 0.740 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.260 0.740 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.260 0.740 0.000
I12.0 Hypertensive renal disease with renal failure
0.259 0.741 0.000
I05 Rheumatic mitral valve diseases
0.257 0.743 0.000
I60-I69 Cerebrovascular diseases
0.249 0.751 0.000
I07.1 Tricuspid insufficiency
0.238 0.762 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.222 0.777 0.000
I01.8 Other acute rheumatic heart disease
0.222 0.777 0.000
I01.2 Acute rheumatic myocarditis
0.222 0.777 0.000
I01.1 Acute rheumatic endocarditis
0.222 0.777 0.000
I01.0 Acute rheumatic pericarditis
0.222 0.777 0.000
I02.9 Rheumatic chorea without heart involvement
0.222 0.777 0.000
I02.0 Rheumatic chorea with heart involvement
0.222 0.777 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.221 0.778 0.000
I09.9 Rheumatic heart disease, unspecified
0.221 0.779 0.000
I07.9 Tricuspid valve disease, unspecified
0.213 0.787 0.000
I07.8 Other tricuspid valve diseases
0.213 0.787 0.000
I07.2 Tricuspid stenosis with insufficiency
0.213 0.787 0.000
I07.0 Tricuspid stenosis
0.213 0.787 0.000
I27.1 Kyphoscoliotic heart disease
0.212 0.788 0.000
I27.2 Other secondary pulmonary hypertension
0.209 0.791 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.209 0.791 0.000
I27.8 Other specified pulmonary heart diseases
0.206 0.793 0.000
I09.8 Other specified rheumatic heart diseases
0.206 0.794 0.000
I09.2 Chronic rheumatic pericarditis
0.206 0.794 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.206 0.794 0.000
I09.0 Rheumatic myocarditis
0.206 0.794 0.000
I61 Intracerebral haemorrhage
0.204 0.796 0.000
I62 Other nontraumatic intracranial haemorrhage
0.201 0.799 0.000
I05.2 Mitral stenosis with insufficiency
0.199 0.801 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.195 0.805 0.000
I06.8 Other rheumatic aortic valve diseases
0.195 0.805 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.195 0.805 0.000
I06.1 Rheumatic aortic insufficiency
0.195 0.805 0.000
I06.0 Rheumatic aortic stenosis
0.195 0.805 0.000
I27.0 Primary pulmonary hypertension
0.193 0.807 0.000
I05.0 Mitral stenosis
0.187 0.812 0.000
I05.1 Rheumatic mitral insufficiency
0.185 0.815 0.000
I05.8 Other mitral valve diseases
0.184 0.816 0.000
I27.9 Pulmonary heart disease, unspecified
0.180 0.820 0.000
I65.2 Occlusion and stenosis of carotid artery
0.180 0.820 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.179 0.821 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.179 0.821 0.000
I67 Other cerebrovascular diseases
0.175 0.825 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.174 0.826 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.168 0.831 0.000
I08 Multiple valve diseases
0.168 0.832 0.000
I67.2 Cerebral atherosclerosis
0.167 0.833 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.165 0.835 0.000
I61.8 Other intracerebral haemorrhage
0.156 0.844 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.151 0.849 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.150 0.850 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.150 0.850 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.150 0.850 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.150 0.850 0.000
I65.1 Occlusion and stenosis of basilar artery
0.150 0.850 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.150 0.850 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.147 0.853 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.147 0.853 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.147 0.853 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.147 0.853 0.000
I62.1 Nontraumatic extradural haemorrhage
0.144 0.856 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.144 0.856 0.000
I69 Sequelae of cerebrovascular disease
0.142 0.858 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.142 0.858 0.000
I12.9 Hypertensive renal disease without renal failure
0.139 0.860 0.000
I05.9 Mitral valve disease, unspecified
0.139 0.861 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.128 0.871 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.128 0.871 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.128 0.871 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.128 0.871 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.128 0.871 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.128 0.871 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.128 0.871 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.128 0.871 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.128 0.871 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.128 0.871 0.000
I68.0 Cerebral amyloid angiopathy
0.128 0.871 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.127 0.872 0.001
I61.9 Intracerebral haemorrhage, unspecified
0.127 0.873 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.126 0.874 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.126 0.874 0.000
I67.5 Moyamoya disease
0.126 0.874 0.000
I67.4 Hypertensive encephalopathy
0.126 0.874 0.000
I67.3 Progressive vascular leukoencephalopathy
0.126 0.874 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.126 0.874 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.124 0.876 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.124 0.876 0.000
I08.9 Multiple valve disease, unspecified
0.120 0.879 0.000
I08.8 Other multiple valve diseases
0.117 0.883 0.000
I67.8 Other specified cerebrovascular diseases
0.115 0.885 0.000
I60 Subarachnoid haemorrhage
0.114 0.885 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.104 0.896 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.102 0.898 0.000
I08.0 Disorders of both mitral and aortic valves
0.099 0.901 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.097 0.903 0.000
I69.3 Sequelae of cerebral infarction
0.092 0.908 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.091 0.908 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.086 0.914 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.082 0.918 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.082 0.918 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.082 0.918 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.082 0.918 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.082 0.918 0.000
I67.1 Cerebral aneurysm, nonruptured
0.081 0.918 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.079 0.921 0.000
I60.8 Other subarachnoid haemorrhage
0.075 0.925 0.000
I30-I52 Other forms of heart disease
0.074 0.926 0.000
I50.1 Left ventricular failure
0.073 0.927 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.072 0.928 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.071 0.928 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.071 0.929 0.000
I50 Heart failure
0.070 0.930 0.000
I63 Cerebral infarction
0.066 0.934 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.065 0.935 0.000
I30 Acute pericarditis
0.065 0.935 0.000
I42 Cardiomyopathy
0.062 0.938 0.000
I42.9 Cardiomyopathy, unspecified
0.061 0.939 0.000
I30.9 Acute pericarditis, unspecified
0.059 0.941 0.000
I37 Pulmonary valve disorders
0.058 0.942 0.000
I46 Cardiac arrest
0.058 0.942 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.056 0.943 0.000
I36 Nonrheumatic tricuspid valve disorders
0.056 0.944 0.000
I81 Portal vein thrombosis
0.055 0.945 0.000
I33 Acute and subacute endocarditis
0.054 0.946 0.000
I52 Other heart disorders in diseases classified elsewhere
0.053 0.946 0.000
I48 Atrial fibrillation and flutter
0.053 0.946 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.053 0.946 0.000
I41 Myocarditis in diseases classified elsewhere
0.053 0.946 0.000
I40 Acute myocarditis
0.053 0.946 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.053 0.946 0.000
I32 Pericarditis in diseases classified elsewhere
0.053 0.946 0.000
I85 Oesophageal varices
0.053 0.947 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.052 0.948 0.000
I31 Other diseases of pericardium
0.052 0.948 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.051 0.949 0.000
I67.9 Cerebrovascular disease, unspecified
0.050 0.950 0.000
I88 Nonspecific lymphadenitis
0.049 0.950 0.000
I83 Varicose veins of lower extremities
0.048 0.952 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.047 0.953 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.047 0.953 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.047 0.953 0.000
I30.8 Other forms of acute pericarditis
0.047 0.953 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.047 0.953 0.000
I37.1 Pulmonary valve insufficiency
0.046 0.954 0.000
I86 Varicose veins of other sites
0.046 0.954 0.000
I42.2 Other hypertrophic cardiomyopathy
0.046 0.954 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.045 0.954 0.000
I46.0 Cardiac arrest with successful resuscitation
0.045 0.955 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.045 0.955 0.000
I85.9 Oesophageal varices without bleeding
0.045 0.955 0.000
I30.1 Infective pericarditis
0.045 0.955 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.045 0.955 0.000
I42.5 Other restrictive cardiomyopathy
0.045 0.955 0.000
I42.4 Endocardial fibroelastosis
0.045 0.955 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.045 0.955 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.045 0.955 0.000
I87 Other disorders of veins
0.044 0.956 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.043 0.957 0.000
I31.0 Chronic adhesive pericarditis
0.042 0.957 0.000
I42.6 Alcoholic cardiomyopathy
0.042 0.958 0.000
I89.0 Lymphoedema, not elsewhere classified
0.042 0.958 0.000
I46.9 Cardiac arrest, unspecified
0.042 0.958 0.000
I37.9 Pulmonary valve disorder, unspecified
0.042 0.958 0.000
I37.8 Other pulmonary valve disorders
0.042 0.958 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.042 0.958 0.000
I37.0 Pulmonary valve stenosis
0.042 0.958 0.000
I46.1 Sudden cardiac death, so described
0.041 0.958 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.041 0.959 0.000
I31.9 Disease of pericardium, unspecified
0.041 0.959 0.000
I51 Complications and ill-defined descriptions of heart disease
0.041 0.959 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.040 0.960 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.040 0.960 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.040 0.960 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.040 0.960 0.000
I33.0 Acute and subacute infective endocarditis
0.040 0.960 0.000
I42.8 Other cardiomyopathies
0.039 0.960 0.000
I89.1 Lymphangitis
0.039 0.960 0.000
I33.9 Acute endocarditis, unspecified
0.039 0.961 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.038 0.961 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.038 0.961 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.038 0.961 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.038 0.961 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.038 0.961 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.038 0.961 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.038 0.961 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.038 0.961 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.038 0.961 0.000
I40.9 Acute myocarditis, unspecified
0.038 0.961 0.000
I40.8 Other acute myocarditis
0.038 0.961 0.000
I40.1 Isolated myocarditis
0.038 0.961 0.000
I40.0 Infective myocarditis
0.038 0.961 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.038 0.961 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.038 0.961 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.038 0.961 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.038 0.961 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.038 0.961 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.038 0.961 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.038 0.961 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.038 0.961 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.038 0.961 0.000
I48.4 Atypical atrial flutter
0.038 0.961 0.000
I48.3 Typical atrial flutter
0.038 0.961 0.000
I48.2 Chronic atrial fibrillation
0.038 0.961 0.000
I48.1 Persistent atrial fibrillation
0.038 0.961 0.000
I48.0 Paroxysmal atrial fibrillation
0.038 0.961 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.038 0.961 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.038 0.961 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.038 0.961 0.000
I31.8 Other specified diseases of pericardium
0.037 0.963 0.000
I31.2 Haemopericardium, not elsewhere classified
0.037 0.963 0.000
I31.1 Chronic constrictive pericarditis
0.037 0.963 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.963 0.037
I42.1 Obstructive hypertrophic cardiomyopathy
0.037 0.963 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.963 0.037
I34 Nonrheumatic mitral valve disorders
0.037 0.963 0.000
M10.99 Gout, unspecified (Site unspecified)
0.036 0.964 0.000
I50.9 Heart failure, unspecified
0.036 0.964 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.964 0.036
I51.6 Cardiovascular disease, unspecified
0.036 0.964 0.000
I88.8 Other nonspecific lymphadenitis
0.036 0.964 0.000
I88.1 Chronic lymphadenitis, except mesenteric
0.036 0.964 0.000
I88.0 Nonspecific mesenteric lymphadenitis
0.036 0.964 0.000
I63.9 Cerebral infarction, unspecified
0.035 0.965 0.000
I38 Endocarditis, valve unspecified
0.035 0.965 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.035 0.965 0.000
I51.9 Heart disease, unspecified
0.034 0.966 0.000
I82 Other venous embolism and thrombosis
0.033 0.966 0.000
I88.9 Nonspecific lymphadenitis, unspecified
0.033 0.967 0.000
I50.0 Congestive heart failure
0.033 0.967 0.000
I86.4 Gastric varices
0.033 0.967 0.000
I86.3 Vulval varices
0.033 0.967 0.000
I86.2 Pelvic varices
0.033 0.967 0.000
I86.0 Sublingual varices
0.033 0.967 0.000
I86.8 Varicose veins of other specified sites
0.033 0.967 0.000
I63.8 Other cerebral infarction
0.032 0.967 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.032 0.968 0.000
I87.9 Disorder of vein, unspecified
0.031 0.968 0.000
I87.0 Postphlebitic syndrome
0.031 0.968 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.969 0.031
I87.2 Venous insufficiency (chronic) (peripheral)
0.031 0.969 0.000
I80 Phlebitis and thrombophlebitis
0.030 0.970 0.000
I85.0 Oesophageal varices with bleeding
0.030 0.970 0.000
E11 Non-insulin-dependent diabetes mellitus
0.030 0.970 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.029 0.971 0.000
I51.5 Myocardial degeneration
0.029 0.971 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.029 0.971 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.029 0.971 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.971 0.029
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.971 0.029
E14 Unspecified diabetes mellitus
0.029 0.971 0.000
I87.1 Compression of vein
0.029 0.971 0.000
E14.9 Without complications
0.029 0.971 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.971 0.029
I51.3 Intracardiac thrombosis, not elsewhere classified
0.028 0.971 0.000
E10-E14 Diabetes mellitus
0.028 0.972 0.000
I51.0 Cardiac septal defect, acquired
0.028 0.972 0.000
E11.5 With peripheral circulatory complications
0.028 0.972 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.027 0.972 0.000
I51.4 Myocarditis, unspecified
0.027 0.973 0.000
I86.1 Scrotal varices
0.027 0.973 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.973 0.027
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.027 0.973 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.026 0.973 0.001
I87.8 Other specified disorders of veins
0.027 0.973 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.973 0.027
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.973 0.027
I49 Other cardiac arrhythmias
0.027 0.973 0.000
I42.0 Dilated cardiomyopathy
0.027 0.973 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.973 0.027
E11.2 With renal complications
0.027 0.973 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.026 0.973 0.000
I34.1 Mitral (valve) prolapse
0.026 0.974 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.026 0.974 0.000
I44 Atrioventricular and left bundle-branch block
0.025 0.975 0.000
I49.1 Atrial premature depolarisation
0.025 0.975 0.000
E11.0 With coma
0.025 0.975 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.025 0.975 0.000
M06 Other rheumatoid arthritis
0.001 0.975 0.024
I45 Other conduction disorders
0.025 0.975 0.000
I82.3 Embolism and thrombosis of renal vein
0.024 0.976 0.000
I82.1 Thrombophlebitis migrans
0.024 0.976 0.000
I82.0 Budd-Chiari syndrome
0.024 0.976 0.000
I82.2 Embolism and thrombosis of vena cava
0.024 0.976 0.000
E11.1 With ketoacidosis
0.024 0.976 0.000
E14.6 With other specified complications
0.023 0.977 0.000
E14.1 With ketoacidosis
0.023 0.977 0.000
E14.8 With unspecified complications
0.023 0.977 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.023 0.977 0.000
E11.3 With ophthalmic complications
0.023 0.977 0.000
E10 Insulin-dependent diabetes mellitus
0.023 0.977 0.000
E14.4 With neurological complications
0.022 0.978 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.022 0.978 0.000
E11.6 With other specified complications
0.022 0.978 0.000
E11.4 With neurological complications
0.022 0.978 0.000
I44.7 Left bundle-branch block, unspecified
0.022 0.978 0.000
E11.7 With multiple complications
0.021 0.979 0.000
E14.7 With multiple complications
0.021 0.979 0.000
E14.5 With peripheral circulatory complications
0.021 0.979 0.000
E14.2 Withrenal complications
0.021 0.979 0.000
E14.0 With coma
0.021 0.979 0.000
M10.9 Gout, unspecified
0.020 0.979 0.001
I51.8 Other ill-defined heart diseases
0.021 0.979 0.000
I49.4 Other and unspecified premature depolarisation
0.021 0.979 0.000
I44.3 Other and unspecified atrioventricular block
0.020 0.980 0.000
I44.6 Other and unspecified fascicular block
0.020 0.980 0.000
E12 Malnutrition-related diabetes mellitus
0.020 0.980 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.020 0.980 0.000
M06.0 Seronegative rheumatoid arthritis
0.001 0.980 0.020
I82.9 Embolism and thrombosis of unspecified vein
0.020 0.980 0.000
E10.9 Without complications
0.020 0.980 0.000
I49.2 Junctional premature depolarisation
0.019 0.980 0.000
I47 Paroxysmal tachycardia
0.019 0.981 0.000
E11.9 Without complications
0.019 0.981 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.019 0.981 0.000
I45.2 Bifascicular block
0.019 0.981 0.000
E11.8 With unspecified complications
0.019 0.981 0.000
E10.2 With renal complications
0.019 0.981 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.981 0.018
I44.5 Left posterior fascicular block
0.018 0.982 0.000
I44.4 Left anterior fascicular block
0.018 0.982 0.000
I31.3 Pericardial effusion (noninflammatory)
0.018 0.982 0.000
E14.3 With ophthalmic complications
0.018 0.982 0.000
Z82.2 Family history of deafness and hearing loss
0.018 0.982 0.000
M06.4 Inflammatory polyarthropathy
0.001 0.982 0.017
I35 Nonrheumatic aortic valve disorders
0.018 0.982 0.000
M06.8 Other specified rheumatoid arthritis
0.001 0.982 0.017
M06.3 Rheumatoid nodule
0.001 0.982 0.017
M06.2 Rheumatoid bursitis
0.001 0.982 0.017
M06.1 Adult-onset Still's disease
0.001 0.982 0.017
I45.4 Nonspecific intraventricular block
0.018 0.982 0.000
I45.0 Right fascicular block
0.018 0.982 0.000
I45.5 Other specified heart block
0.018 0.982 0.000
I45.3 Trifascicular block
0.018 0.982 0.000
I45.8 Other specified conduction disorders
0.017 0.983 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.017 0.983 0.000
E10.8 With unspecified complications
0.017 0.983 0.000
E10.0 With coma
0.017 0.983 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.017 0.983 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.017 0.983 0.000
Z82.1 Family history of blindness and visual loss
0.017 0.983 0.000
E13 Other specified diabetes mellitus
0.016 0.983 0.000
E10.7 With multiple complications
0.016 0.984 0.000
E10.6 With other specified complications
0.016 0.984 0.000
I45.6 Preexcitation syndrome
0.016 0.984 0.000
I49.8 Other specified cardiac arrhythmias
0.016 0.984 0.000
E10.5 With peripheral circulatory complications
0.016 0.984 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.016 0.984 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.015 0.984 0.001
I82.8 Embolism and thrombosis of other specified veins
0.015 0.984 0.000
I49.0 Ventricular fibrillation and flutter
0.015 0.985 0.000
M10.98 Gout, unspecified (Other)
0.014 0.985 0.001
M10.95 Gout, unspecified (Pelvic region and thigh)
0.014 0.985 0.001
M10.94 Gout, unspecified (Hand)
0.014 0.985 0.001
M10.93 Gout, unspecified (Forearm)
0.014 0.985 0.001
M10.92 Gout, unspecified (Upper arm)
0.014 0.985 0.001
M10.91 Gout, unspecified (Shoulder region)
0.014 0.985 0.001
I35.2 Aortic (valve) stenosis with insufficiency
0.015 0.985 0.000
E12.9 Without complications
0.015 0.985 0.000
E12.8 With unspecified complications
0.015 0.985 0.000
E12.7 With multiple complications
0.015 0.985 0.000
E12.6 With other specified complications
0.015 0.985 0.000
E12.5 With peripheral circulatory complications
0.015 0.985 0.000
E12.4 With neurological complications
0.015 0.985 0.000
E12.3 With ophthalmic complications
0.015 0.985 0.000
E12.2 With renal complications
0.015 0.985 0.000
E12.1 With ketoacidosis
0.015 0.985 0.000
E12.0 With coma
0.015 0.985 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.001 0.985 0.014
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.001 0.985 0.014
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.001 0.985 0.014
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.001 0.985 0.014
M06.04 Seronegative rheumatoid arthritis (Hand)
0.001 0.985 0.014
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.001 0.985 0.014
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.001 0.985 0.014
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.001 0.985 0.014
E10.3 With ophthalmic complications
0.015 0.985 0.000
M10.90 Gout, unspecified (Multiple sites)
0.014 0.985 0.001
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.015 0.985 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.014 0.986 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.014 0.986 0.000
M10 Gout
0.010 0.986 0.004
Z82.3 Family history of stroke
0.014 0.986 0.000
G90-G99 Other disorders of the nervous system
0.014 0.986 0.000
E20-E35 Disorders of other endocrine glands
0.014 0.986 0.000
G93 Other disorders of brain
0.014 0.986 0.000
M10.96 Gout, unspecified (Lower leg)
0.013 0.986 0.001
E10.4 With neurological complications
0.013 0.986 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.011 0.986 0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.001 0.986 0.013
E10.1 With ketoacidosis
0.013 0.986 0.000
G91 Hydrocephalus
0.013 0.986 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.987 0.013
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.001 0.987 0.013
M06.46 Inflammatory polyarthropathy (Lower leg)
0.001 0.987 0.013
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.001 0.987 0.013
M06.44 Inflammatory polyarthropathy (Hand)
0.001 0.987 0.013
M06.43 Inflammatory polyarthropathy (Forearm)
0.001 0.987 0.013
M06.42 Inflammatory polyarthropathy (Upper arm)
0.001 0.987 0.013
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.001 0.987 0.013
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.001 0.987 0.013
I49.5 Sick sinus syndrome
0.013 0.987 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.001 0.987 0.012
M06.18 Adult-onset Still's disease (Other)
0.001 0.987 0.012
M06.17 Adult-onset Still's disease (Ankle and foot)
0.001 0.987 0.012
M06.16 Adult-onset Still's disease (Lower leg)
0.001 0.987 0.012

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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