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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3796587
log Bayes Factor = 17.9101
Chromosome 4   position 156,638,073  (GRCh37) Explore rs3796587 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.001 0.999
I20.9 Angina pectoris, unspecified
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.007 0.993
I20.0 Unstable angina
0.000 0.031 0.969
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.034 0.966
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.034 0.966
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.039 0.961
Z95.4 Presence of other heart-valve replacement
0.000 0.042 0.958
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.045 0.955
I25.2 Old myocardial infarction
0.000 0.064 0.936
I22 Subsequent myocardial infarction
0.000 0.064 0.936
I25.5 Ischaemic cardiomyopathy
0.000 0.065 0.935
I10-I15 Hypertensive diseases
0.000 0.097 0.903
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.100 0.900
I25.4 Coronary artery aneurysm
0.000 0.111 0.889
I24 Other acute ischaemic heart diseases
0.000 0.111 0.889
Z95.3 Presence of xenogenic heart valve
0.000 0.121 0.879
Chapter IX Diseases of the circulatory system
0.000 0.137 0.863
I24.8 Other forms of acute ischaemic heart disease
0.000 0.194 0.806
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.210 0.790
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.213 0.787
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.226 0.774
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.269 0.731
I71 Aortic aneurysm and dissection
0.000 0.279 0.721
Z95.2 Presence of prosthetic heart valve
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I20.8 Other forms of angina pectoris
0.000 0.305 0.695
I23 Certain current complications following acute myocardial infarction
0.000 0.305 0.695
I74 Arterial embolism and thrombosis
0.000 0.309 0.691
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.313 0.687
I15 Secondary hypertension
0.000 0.325 0.674
I77 Other disorders of arteries and arterioles
0.000 0.338 0.662
I70 Atherosclerosis
0.000 0.339 0.661
I13 Hypertensive heart and renal disease
0.000 0.353 0.647
Z95.1 Presence of aortocoronary bypass graft
0.000 0.361 0.639
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.371 0.629
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.381 0.619
I00-I02 Acute rheumatic fever
0.000 0.381 0.619
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.383 0.617
C77.2 Intra-abdominal lymph nodes
0.602 0.398 0.000
I11 Hypertensive heart disease
0.000 0.399 0.601
I25.3 Aneurysm of heart
0.000 0.405 0.595
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.585 0.415 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.417 0.583
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.418 0.582
I70.0 Atherosclerosis of aorta
0.000 0.427 0.573
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.427 0.573
C77.9 Lymph node, unspecified
0.572 0.428 0.000
I71.0 Dissection of aorta [any part]
0.000 0.432 0.568
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.448 0.552
I24.1 Dressler's syndrome
0.000 0.452 0.548
I74.8 Embolism and thrombosis of other arteries
0.000 0.455 0.545
C77.8 Lymph nodes of multiple regions
0.531 0.469 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.470 0.529
I72 Other aneurysm
0.000 0.480 0.520
I15.1 Hypertension secondary to other renal disorders
0.000 0.480 0.520
I70.1 Atherosclerosis of renal artery
0.000 0.482 0.518
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.483 0.517
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.483 0.517
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.483 0.517
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.483 0.517
C77.4 Inguinal and lower limb lymph nodes
0.512 0.488 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.490 0.510
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.499 0.501
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.502 0.498
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.502 0.498
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.502 0.498
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.502 0.498
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.502 0.498
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.502 0.498
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.502 0.498
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.504 0.495
I77.1 Stricture of artery
0.000 0.506 0.494
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.506 0.494
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.487 0.513 0.000
I22.8 Subsequent myocardial infarction of other sites
0.000 0.515 0.485
I15.8 Other secondary hypertension
0.000 0.516 0.484
I15.2 Hypertension secondary to endocrine disorders
0.000 0.516 0.484
I15.0 Renovascular hypertension
0.000 0.516 0.484
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.479 0.521 0.000
I77.0 Arteriovenous fistula, acquired
0.000 0.521 0.478
I23.8 Other current complications following acute myocardial infarction
0.000 0.523 0.476
I77.5 Necrosis of artery
0.000 0.525 0.475
I77.4 Coeliac artery compression syndrome
0.000 0.525 0.475
I77.3 Arterial fibromuscular dysplasia
0.000 0.525 0.475
I70.9 Generalised and unspecified atherosclerosis
0.000 0.526 0.474
I12 Hypertensive renal disease
0.000 0.526 0.474
I15.9 Seconday hypertension, unspecified
0.000 0.527 0.473
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.529 0.471
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.536 0.464
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.536 0.464
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.536 0.464
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.536 0.464
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.542 0.458
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.450 0.550 0.000
I70.8 Atherosclerosis of other arteries
0.000 0.550 0.450
I02 Rheumatic chorea
0.000 0.556 0.444
I01 Rheumatic fever with heart involvement
0.000 0.556 0.444
I00 Rheumatic fever without mention of heart involvement
0.000 0.556 0.444
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.564 0.436
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.567 0.433
C78.2 Secondary malignant neoplasm of pleura
0.430 0.570 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.585 0.415
I72.0 Aneurysm of carotid artery
0.000 0.587 0.413
I72.9 Aneurysm of unspecified site
0.000 0.589 0.411
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.589 0.411
I79.1 Aortitis in diseases classified elsewhere
0.000 0.589 0.411
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.589 0.411
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.592 0.408
C77.3 Axillary and upper limb lymph nodes
0.408 0.592 0.000
I77.2 Rupture of artery
0.000 0.593 0.407
I77.8 Other specified disorders of arteries and arterioles
0.000 0.599 0.401
I72.2 Aneurysm of renal artery
0.000 0.602 0.398
C78.0 Secondary malignant neoplasm of lung
0.377 0.623 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.376 0.624 0.000
I72.3 Aneurysm of iliac artery
0.000 0.625 0.375
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.627 0.373
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.627 0.373
I72.1 Aneurysm of artery of upper extremity
0.000 0.627 0.373
C78.7 Secondary malignant neoplasm of liver
0.372 0.628 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.629 0.371
I78 Diseases of capillaries
0.000 0.636 0.364
I74.5 Embolism and thrombosis of iliac artery
0.000 0.639 0.361
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.357 0.643 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.645 0.355
I77.6 Arteritis, unspecified
0.000 0.648 0.352
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.656 0.344
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.660 0.340
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.660 0.340
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.336 0.664 0.000
C77.0 Lymph nodes of head, face and neck
0.332 0.668 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.670 0.330
C78.1 Secondary malignant neoplasm of mediastinum
0.328 0.672 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.673 0.327
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.673 0.326
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.677 0.323
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.678 0.322
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.681 0.318
I01.8 Other acute rheumatic heart disease
0.000 0.681 0.318
I01.2 Acute rheumatic myocarditis
0.000 0.681 0.318
I01.1 Acute rheumatic endocarditis
0.000 0.681 0.318
I01.0 Acute rheumatic pericarditis
0.000 0.681 0.318
I02.9 Rheumatic chorea without heart involvement
0.000 0.681 0.318
I02.0 Rheumatic chorea with heart involvement
0.000 0.681 0.318
C76 Malignant neoplasm of other and ill-defined sites
0.318 0.682 0.000
I72.4 Aneurysm of artery of lower extremity
0.000 0.685 0.315
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.690 0.310
I21 Acute myocardial infarction
0.000 0.693 0.307
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.701 0.298
C80 Malignant neoplasm without specification of site
0.286 0.714 0.000
I20.1 Angina pectoris with documented spasm
0.001 0.716 0.283
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.281 0.719 0.000
C15-C26 Malignant neoplasms of digestive organs
0.280 0.720 0.000
C25 Malignant neoplasm of pancreas
0.277 0.723 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.725 0.275
Chapter II Neoplasms
0.272 0.728 0.000
C25.0 Head of pancreas
0.271 0.729 0.000
I78.8 Other diseases of capillaries
0.000 0.733 0.266
I73 Other peripheral vascular diseases
0.000 0.733 0.267
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.737 0.263
C56 Malignant neoplasm of ovary
0.261 0.739 0.000
I78.9 Disease of capillaries, unspecified
0.000 0.739 0.261
C51-C58 Malignant neoplasms of female genital organs
0.261 0.739 0.000
C20 Malignant neoplasm of rectum
0.260 0.740 0.000
C21 Malignant neoplasm of anus and anal canal
0.258 0.742 0.000
D00-D09 In situ neoplasms
0.254 0.746 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.251 0.749 0.000
C17 Malignant neoplasm of small intestine
0.242 0.758 0.000
C21.0 Anus, unspecified
0.240 0.760 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.239 0.761 0.000
I95 Hypotension
0.000 0.764 0.236
D03 Melanoma in situ
0.234 0.766 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.770 0.230
I95.2 Hypotension due to drugs
0.000 0.770 0.230
C76.3 Pelvis
0.229 0.771 0.000
I99 Other and unspecified disorders of circulatory system
0.000 0.771 0.229
C76.8 Overlapping lesion of other and ill-defined sites
0.228 0.772 0.000
C76.7 Other ill-defined sites
0.228 0.772 0.000
C76.5 Lower limb
0.228 0.772 0.000
C76.4 Upper limb
0.228 0.772 0.000
C76.2 Abdomen
0.228 0.772 0.000
C25.9 Pancreas, unspecified
0.228 0.772 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.774 0.226
D37-D48 Neoplasms of uncertain or unknown behaviour
0.226 0.774 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.775 0.225
D05 Carcinoma in situ of breast
0.224 0.776 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.779 0.220
D03.5 Melanoma in situ of trunk
0.219 0.781 0.000
C76.1 Thorax
0.217 0.782 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.216 0.783 0.000
C25.4 Endocrine pancreas
0.216 0.784 0.000
C77.5 Intrapelvic lymph nodes
0.215 0.785 0.000
C22.9 Liver, unspecified
0.215 0.785 0.000
D09 Carcinoma in situ of other and unspecified sites
0.215 0.785 0.000
C25.8 Overlapping lesion of pancreas
0.214 0.786 0.000
C17.9 Small intestine, unspecified
0.213 0.787 0.000
C25.2 Tail of pancreas
0.212 0.788 0.000
C80.9 Malignant neoplasm, unspecified
0.210 0.790 0.000
D05.0 Lobular carcinoma in situ
0.210 0.790 0.000
C22.1 Intrahepatic bile duct carcinoma
0.209 0.791 0.000
C76.0 Head, face and neck
0.208 0.792 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.792 0.208
I21.4 Acute subendocardial myocardial infarction
0.000 0.792 0.208
D46 Myelodysplastic syndromes
0.206 0.794 0.000
C16 Malignant neoplasm of stomach
0.206 0.794 0.000
I72.8 Aneurysm of other specified arteries
0.001 0.796 0.203
C40-C41 Malignant neoplasms of bone and articular cartilage
0.203 0.796 0.000
I05-I09 Chronic rheumatic heart diseases
0.000 0.796 0.204
C71 Malignant neoplasm of brain
0.201 0.799 0.000
I28 Other diseases of pulmonary vessels
0.000 0.799 0.201
C25.3 Pancreatic duct
0.201 0.799 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.199 0.800 0.000
C25.7 Other parts of pancreas
0.199 0.801 0.000
C69 Malignant neoplasm of eye and adnexa
0.198 0.802 0.000
C21.1 Anal canal
0.198 0.802 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.197 0.803 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.809 0.191
C17.1 Jejunum
0.191 0.809 0.000
C23 Malignant neoplasm of gallbladder
0.191 0.809 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.810 0.189
C51 Malignant neoplasm of vulva
0.188 0.812 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.188 0.812 0.000
C52 Malignant neoplasm of vagina
0.188 0.812 0.000
C58 Malignant neoplasm of placenta
0.187 0.813 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.187 0.813 0.000
D06 Carcinoma in situ of cervix uteri
0.187 0.813 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.186 0.814 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.186 0.814 0.000
C22.0 Liver cell carcinoma
0.186 0.814 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.815 0.185
C21.2 Cloacogenic zone
0.185 0.815 0.000
D09.0 Bladder
0.185 0.815 0.000
C71.1 Frontal lobe
0.185 0.815 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.183 0.817 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.183 0.817 0.000
D37.5 Rectum
0.182 0.818 0.000
C22.7 Other specified carcinomas of liver
0.180 0.820 0.000
C22.4 Other sarcomas of liver
0.180 0.820 0.000
C22.3 Angiosarcoma of liver
0.180 0.820 0.000
C22.2 Hepatoblastoma
0.180 0.820 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.180 0.820 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.180 0.820 0.000
D45 Polycythaemia vera
0.180 0.820 0.000
C16.1 Fundus of stomach
0.179 0.821 0.000
D05.1 Intraductal carcinoma in situ
0.179 0.821 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.177 0.823 0.000
C17.8 Overlapping lesion of small intestine
0.174 0.826 0.000
C17.3 Meckel's diverticulum
0.174 0.826 0.000
C57.0 Fallopian tube
0.173 0.826 0.000
C71.9 Brain, unspecified
0.173 0.827 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.173 0.827 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.172 0.828 0.000
C17.0 Duodenum
0.172 0.828 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.172 0.828 0.000
C70 Malignant neoplasm of meninges
0.172 0.828 0.000
D05.7 Other carcinoma in situ of breast
0.172 0.828 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.172 0.828 0.000
C53 Malignant neoplasm of cervix uteri
0.172 0.828 0.000
C16.6 Greater curvature of stomach, unspecified
0.171 0.829 0.000
C57.9 Female genital organ, unspecified
0.171 0.829 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.169 0.831 0.000
D46.1 Refractory anaemia with sideroblasts
0.169 0.831 0.000
D03.9 Melanoma in situ, unspecified
0.168 0.832 0.000
D03.8 Melanoma in situ of other sites
0.168 0.832 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.168 0.832 0.000
D03.0 Melanoma in situ of lip
0.168 0.832 0.000
D03.4 Melanoma in situ of scalp and neck
0.166 0.834 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.163 0.837 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.837 0.163
C69.3 Choroid
0.163 0.837 0.000
D37.7 Other digestive organs
0.163 0.837 0.000
D43.2 Brain, unspecified
0.162 0.838 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.838 0.162
I97.0 Postcardiotomy syndrome
0.000 0.838 0.162
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.162 0.838 0.000
C25.1 Body of pancreas
0.162 0.838 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.162 0.838 0.000
I95.0 Idiopathic hypotension
0.000 0.838 0.161
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.160 0.840 0.000
C16.4 Pylorus
0.159 0.841 0.000
C17.2 Ileum
0.159 0.841 0.000
I95.8 Other hypotension
0.000 0.841 0.159
D09.1 Other and unspecified urinary organs
0.157 0.843 0.000
D46.2 Refractory anaemia with excess of blasts
0.157 0.843 0.000
C71.8 Overlapping lesion of brain
0.156 0.844 0.000
C57.8 Overlapping lesion of female genital organs
0.155 0.845 0.000
C57.7 Other specified female genital organs
0.155 0.845 0.000
C57.4 Uterine adnexa, unspecified
0.155 0.845 0.000
C57.3 Parametrium
0.155 0.845 0.000
C57.2 Round ligament
0.155 0.845 0.000
C57.1 Broad ligament
0.155 0.845 0.000
D07.5 Prostate
0.155 0.845 0.000
I27 Other pulmonary heart diseases
0.000 0.845 0.155
D09.9 Carcinoma in situ, unspecified
0.154 0.846 0.000
D09.7 Carcinoma in situ of other specified sites
0.154 0.846 0.000
D09.3 Thyroid and other endocrine glands
0.154 0.846 0.000
D09.2 Eye
0.154 0.846 0.000
D46.7 Other myelodysplastic syndromes
0.153 0.847 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.152 0.848 0.000
C16.0 Cardia
0.150 0.850 0.000
C69.9 Eye, unspecified
0.150 0.850 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.149 0.851 0.000
C71.3 Parietal lobe
0.149 0.851 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.148 0.852 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.148 0.852 0.000
D46.4 Refractory anaemia, unspecified
0.148 0.852 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.148 0.852 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.148 0.852 0.000
C16.8 Overlapping lesion of stomach
0.148 0.852 0.000
D39.7 Other female genital organs
0.148 0.852 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.146 0.854 0.000
C79 Secondary malignant neoplasm of other sites
0.146 0.854 0.000
C51.0 Labium majus
0.145 0.855 0.000
C69.0 Conjunctiva
0.145 0.855 0.000
C71.7 Brain stem
0.145 0.855 0.000
C71.6 Cerebellum
0.145 0.855 0.000
C71.5 Cerebral ventricle
0.145 0.855 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.856 0.144
I28.1 Aneurysm of pulmonary artery
0.000 0.856 0.144
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.856 0.144
D37.9 Digestive organ, unspecified
0.144 0.856 0.000
C26.0 Intestinal tract, part unspecified
0.144 0.856 0.000
D06.0 Endocervix
0.144 0.856 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.856 0.143
C26.8 Overlapping lesion of digestive system
0.143 0.857 0.000
C26.1 Spleen
0.143 0.857 0.000
C69.8 Overlapping lesion of eye and adnexa
0.142 0.857 0.000
C69.6 Orbit
0.142 0.857 0.000
C69.5 Lachrymal gland and duct
0.142 0.857 0.000
C69.4 Ciliary body
0.142 0.857 0.000
C69.2 Retina
0.142 0.857 0.000
C69.1 Cornea
0.142 0.857 0.000
C26.9 Ill-defined sites within the digestive system
0.141 0.859 0.000
D39.1 Ovary
0.141 0.859 0.000
D41.0 Kidney
0.139 0.861 0.000
D39.0 Uterus
0.139 0.861 0.000
C16.2 Body of stomach
0.139 0.861 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.861 0.139
C24.0 Extrahepatic bile duct
0.139 0.861 0.000
I06 Rheumatic aortic valve diseases
0.000 0.861 0.138
D38.0 Larynx
0.138 0.862 0.000
D37.3 Appendix
0.137 0.863 0.000
D43.0 Brain, supratentorial
0.135 0.864 0.000
C51.8 Overlapping lesion of vulva
0.135 0.865 0.000
C51.2 Clitoris
0.135 0.865 0.000
C51.1 Labium minus
0.135 0.865 0.000
D43.9 Central nervous system, unspecified
0.135 0.865 0.000
D43.7 Other parts of central nervous system
0.135 0.865 0.000
D43.4 Spinal cord
0.135 0.865 0.000
D43.3 Cranial nerves
0.135 0.865 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.134 0.866 0.000
D06.7 Other parts of cervix
0.134 0.866 0.000
D06.1 Exocervix
0.134 0.866 0.000
D39.9 Female genital organ, unspecified
0.133 0.867 0.000
D39.2 Placenta
0.133 0.867 0.000
C18 Malignant neoplasm of colon
0.133 0.867 0.000
D43.1 Brain, infratentorial
0.132 0.867 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.131 0.868 0.000
D02.4 Respiratory system, unspecified
0.131 0.869 0.000
D02.3 Other parts of respiratory system
0.131 0.869 0.000
D02.2 Bronchus and lung
0.131 0.869 0.000
D02.1 Trachea
0.131 0.869 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.131 0.869 0.000
D02.0 Larynx
0.131 0.869 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.130 0.870 0.000
I09 Other rheumatic heart diseases
0.000 0.870 0.130
C24.8 Overlapping lesion of biliary tract
0.129 0.871 0.000
D07.6 Other and unspecified male genital organs
0.129 0.871 0.000
D07.3 Other and unspecified female genital organs
0.129 0.871 0.000
D07.0 Endometrium
0.129 0.871 0.000
C16.5 Lesser curvature of stomach, unspecified
0.129 0.871 0.000
C18.3 Hepatic flexure
0.129 0.871 0.000
I26 Pulmonary embolism
0.000 0.872 0.128
C71.4 Occipital lobe
0.128 0.872 0.000
D06.9 Cervix, unspecified
0.127 0.873 0.000
C24.9 Biliary tract, unspecified
0.127 0.873 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.127 0.873 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.126 0.874 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.126 0.874 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.125 0.875 0.000
C15 Malignant neoplasm of oesophagus
0.124 0.875 0.000
D07.1 Vulva
0.124 0.876 0.000
C51.9 Vulva, unspecified
0.124 0.876 0.000
D01.9 Digestive organ, unspecified
0.124 0.876 0.000
D01.7 Other specified digestive organs
0.124 0.876 0.000
D01.5 Liver, gallbladder and bile ducts
0.124 0.876 0.000
D01.4 Other and unspecified parts of intestine
0.124 0.876 0.000
D01.2 Rectum
0.124 0.876 0.000
D01.1 Rectosigmoid junction
0.124 0.876 0.000
D01.0 Colon
0.124 0.876 0.000
D00.2 Stomach
0.123 0.876 0.000
C70.9 Meninges, unspecified
0.123 0.876 0.000
C70.1 Spinal meninges
0.123 0.876 0.000
C70.0 Cerebral meninges
0.123 0.876 0.000
C72.9 Central nervous system, unspecified
0.123 0.876 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.123 0.876 0.000
C72.5 Other and unspecified cranial nerves
0.123 0.876 0.000
C72.4 Acoustic nerve
0.123 0.876 0.000
C72.3 Optic nerve
0.123 0.876 0.000
C72.2 Olfactory nerve
0.123 0.876 0.000
C72.1 Cauda equina
0.123 0.876 0.000
C72.0 Spinal cord
0.123 0.876 0.000
C41.9 Bone and articular cartilage, unspecified
0.123 0.876 0.000
I28.8 Other specified diseases of pulmonary vessels
0.000 0.877 0.123
C53.8 Overlapping lesion of cervix uteri
0.123 0.877 0.000
C53.1 Exocervix
0.123 0.877 0.000
D38.6 Respiratory organ, unspecified
0.123 0.877 0.000
D38.5 Other respiratory organs
0.123 0.877 0.000
D38.4 Thymus
0.123 0.877 0.000
D38.3 Mediastinum
0.123 0.877 0.000
D38.2 Pleura
0.123 0.877 0.000
D00.1 Oesophagus
0.123 0.877 0.000
D37.0 Lip, oral cavity and pharynx
0.122 0.878 0.000
D41.2 Ureter
0.122 0.878 0.000
D37.1 Stomach
0.121 0.879 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.121 0.879 0.000
C71.0 Cerebrum, except lobes and ventricles
0.121 0.879 0.000
C16.3 Pyloric antrum
0.119 0.880 0.000
C53.0 Endocervix
0.119 0.881 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.117 0.883 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.883 0.117
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.883 0.117
I98.0 Cardiovascular syphilis
0.000 0.883 0.117
I27.0 Primary pulmonary hypertension
0.000 0.883 0.117
D42.9 Meninges, unspecified
0.116 0.884 0.000
D42.1 Spinal meninges
0.116 0.884 0.000
D42.0 Cerebral meninges
0.116 0.884 0.000
I78.1 Naevus, nonneoplastic
0.000 0.884 0.116
D38.1 Trachea, bronchus and lung
0.116 0.884 0.000
C40.2 Long bones of lower limb
0.115 0.884 0.000
C50-C50 Malignant neoplasm of breast
0.115 0.885 0.000
D41.9 Urinary organ, unspecified
0.115 0.885 0.000
D41.7 Other urinary organs
0.115 0.885 0.000
D41.3 Urethra
0.115 0.885 0.000
D41.1 Renal pelvis
0.115 0.885 0.000
D01.3 Anus and anal canal
0.114 0.886 0.000
C79.6 Secondary malignant neoplasm of ovary
0.114 0.886 0.000
D00.0 Lip, oral cavity and pharynx
0.114 0.886 0.000
I97.1 Other functional disturbances following cardiac surgery
0.000 0.887 0.113
C54 Malignant neoplasm of corpus uteri
0.113 0.887 0.000
C53.9 Cervix uteri, unspecified
0.113 0.887 0.000
I07 Rheumatic tricuspid valve diseases
0.000 0.887 0.112
I27.1 Kyphoscoliotic heart disease
0.000 0.889 0.111
C18.0 Caecum
0.111 0.889 0.000
I73.0 Raynaud's syndrome
0.000 0.890 0.110
D07.4 Penis
0.110 0.890 0.000
C40.9 Bone and articular cartilage of limb, unspecified
0.109 0.891 0.000
C40.8 Overlapping lesion of bone and articular cartilage of limbs
0.109 0.891 0.000
C40.3 Short bones of lower limb
0.109 0.891 0.000
C40.1 Short bones of upper limb
0.109 0.891 0.000
C40.0 Scapula and long bones of upper limb
0.109 0.891 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.109 0.891 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.109 0.891 0.000
I05 Rheumatic mitral valve diseases
0.000 0.891 0.109
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.108 0.892 0.000
C79.2 Secondary malignant neoplasm of skin
0.108 0.892 0.000
C74 Malignant neoplasm of adrenal gland
0.107 0.893 0.000
I27.9 Pulmonary heart disease, unspecified
0.000 0.893 0.107
C41.8 Overlapping lesion of bone and articular cartilage
0.107 0.893 0.000
C41.4 Pelvic bones, sacrum and coccyx
0.107 0.893 0.000
C41.3 Ribs, sternum and clavicle
0.107 0.893 0.000
C41.2 Vertebral column
0.107 0.893 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.107 0.893 0.000
D04 Carcinoma in situ of skin
0.106 0.894 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.894 0.106
C18.5 Splenic flexure
0.106 0.894 0.000
D07.2 Vagina
0.106 0.894 0.000
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)
0.105 0.895 0.000
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)
0.105 0.895 0.000
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)
0.105 0.895 0.000
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)
0.105 0.895 0.000
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)
0.105 0.895 0.000
C41.0 Bones of skull and face
0.104 0.896 0.000
C10 Malignant neoplasm of oropharynx
0.103 0.897 0.000
C32 Malignant neoplasm of larynx
0.103 0.897 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.900 0.099
I06.8 Other rheumatic aortic valve diseases
0.000 0.900 0.099
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.900 0.099
I06.0 Rheumatic aortic stenosis
0.000 0.900 0.099
C73 Malignant neoplasm of thyroid gland
0.100 0.900 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.098 0.902 0.000
D37.2 Small intestine
0.098 0.902 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.097 0.903 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.097 0.903 0.000
C04 Malignant neoplasm of floor of mouth
0.096 0.904 0.000
C48.2 Peritoneum, unspecified
0.096 0.904 0.000
C16.9 Stomach, unspecified
0.095 0.904 0.000
C37 Malignant neoplasm of thymus
0.095 0.905 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.095 0.905 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.094 0.906 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.094 0.906 0.000
C31 Malignant neoplasm of accessory sinuses
0.094 0.906 0.000
C33 Malignant neoplasm of trachea
0.094 0.906 0.000
C24.1 Ampulla of Vater
0.094 0.906 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.094 0.906 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.093 0.906 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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