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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3800461
log Bayes Factor = 38.5883
Chromosome 6   position 34,616,322  (GRCh37) Explore rs3800461 on Ensembl!
Variant rs3800461 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
M51 Other intervertebral disk disorders
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
M51.2 Other specified intervertebral disk displacement
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
H55-H59 Other disorders of eye and adnexa
0.995 0.005 0.000
I45 Other conduction disorders
0.994 0.006 0.000
M54.2 Cervicalgia
0.994 0.006 0.000
Chapter VIII Diseases of the ear and mastoid process
0.994 0.006 0.000
I25 Chronic ischaemic heart disease
0.993 0.007 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.992 0.008 0.000
I45.1 Other and unspecified right bundle-branch block
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.991 0.009 0.000
I46 Cardiac arrest
0.991 0.009 0.000
H65-H75 Diseases of middle ear and mastoid
0.991 0.009 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.990 0.010 0.000
M54.22 Cervicalgia (Cervical region)
0.989 0.011 0.000
J95-J99 Other diseases of the respiratory system
0.988 0.012 0.000
M70-M79 Other soft tissue disorders
0.988 0.012 0.000
H01 Other inflammation of eyelid
0.987 0.013 0.000
I25.1 Atherosclerotic heart disease
0.985 0.015 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.985 0.015 0.000
M20-M25 Other joint disorders
0.985 0.015 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.984 0.016 0.000
J98 Other respiratory disorders
0.983 0.017 0.000
H01.0 Blepharitis
0.982 0.018 0.000
I46.0 Cardiac arrest with successful resuscitation
0.982 0.018 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.982 0.018 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.980 0.020 0.000
Z86 Personal history of certain other diseases
0.979 0.021 0.000
J98.4 Other disorders of lung
0.978 0.022 0.000
T66-T78 Other and unspecified effects of external causes
0.978 0.022 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.976 0.024 0.000
M54.9 Dorsalgia, unspecified
0.975 0.025 0.000
M79.6 Pain in limb
0.973 0.027 0.000
T17 Foreign body in respiratory tract
0.972 0.028 0.000
Chapter VI Diseases of the nervous system
0.969 0.031 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.966 0.034 0.000
H74 Other disorders of middle ear and mastoid
0.965 0.035 0.000
M54.5 Low back pain
0.965 0.035 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.964 0.036 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.959 0.041 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.959 0.041 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.958 0.042 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.956 0.044 0.000
Z95.4 Presence of other heart-valve replacement
0.955 0.045 0.000
M54.4 Lumbago with sciatica
0.955 0.045 0.000
Y48 Anaesthetics and therapeutic gases
0.955 0.045 0.000
T17.2 Foreign body in pharynx
0.954 0.046 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.954 0.046 0.000
M13 Other arthritis
0.953 0.047 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.951 0.049 0.000
T78 Adverse effects, not elsewhere classified
0.950 0.050 0.000
M24 Other specific joint derangements
0.949 0.051 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.947 0.053 0.000
M54.56 Low back pain (Lumbar region)
0.946 0.054 0.000
Q00-Q07 Congenital malformations of the nervous system
0.946 0.054 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.942 0.058 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.942 0.058 0.000
M79.0 Rheumatism, unspecified
0.942 0.058 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.940 0.060 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.940 0.060 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.940 0.060 0.000
M07 Psoriatic and enteropathic arthropathies
0.938 0.062 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.935 0.065 0.000
H57 Other disorders of eye and adnexa
0.934 0.066 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.933 0.067 0.000
M35 Other systemic involvement of connective tissue
0.932 0.068 0.000
I26 Pulmonary embolism
0.932 0.068 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.931 0.069 0.000
Z83 Family history of other specific disorders
0.927 0.073 0.000
H71 Cholesteatoma of middle ear
0.926 0.074 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.925 0.075 0.000
G57 Mononeuropathies of lower limb
0.923 0.077 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.922 0.078 0.000
H55 Nystagmus and other irregular eye movements
0.919 0.081 0.000
Q80-Q89 Other congenital malformations
0.911 0.089 0.000
Z99.8 Dependence on other enabling machines and devices
0.911 0.089 0.000
S10-S19 Injuries to the neck
0.911 0.089 0.000
M65-M68 Disorders of synovium and tendon
0.908 0.092 0.000
J84 Other interstitial pulmonary diseases
0.908 0.092 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.905 0.095 0.000
H73 Other disorders of tympanic membrane
0.902 0.098 0.000
Z59 Problems related to housing and economic circumstances
0.900 0.100 0.000
M31 Other necrotising vasculopathies
0.899 0.101 0.000
M13.9 Arthritis, unspecified
0.899 0.101 0.000
Z86.4 Personal history of psychoactive substance abuse
0.899 0.101 0.000
T78.2 Anaphylactic shock, unspecified
0.898 0.102 0.000
Y42.5 Other oestrogens and progestogens
0.897 0.103 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.897 0.103 0.000
I21 Acute myocardial infarction
0.894 0.106 0.000
M07.3 Other psoriatic arthropathies
0.894 0.106 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.893 0.107 0.000
Q05 Spina bifida
0.892 0.108 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.892 0.108 0.000
H10-H13 Disorders of conjunctiva
0.892 0.108 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.892 0.108 0.000
M24.0 Loose body in joint
0.886 0.114 0.000
Z63 Other problems related to primary support group, including family circumstances
0.886 0.114 0.000
Y48.3 Local anaesthetics
0.885 0.115 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.885 0.115 0.000
M79.66 Pain in limb (Lower leg)
0.885 0.115 0.000
M40-M43 Deforming dorsopathies
0.883 0.117 0.000
I51 Complications and ill-defined descriptions of heart disease
0.882 0.118 0.000
G57.8 Other mononeuropathies of lower limb
0.882 0.118 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.881 0.119 0.000
I46.9 Cardiac arrest, unspecified
0.878 0.122 0.000
H53-H54 Visual disturbances and blindness
0.878 0.122 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.876 0.124 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.875 0.125 0.000
Z99.3 Dependence on wheelchair
0.874 0.126 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.874 0.126 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.874 0.126 0.000
M06.3 Rheumatoid nodule
0.873 0.127 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.869 0.131 0.000
H74.0 Tympanosclerosis
0.868 0.132 0.000
M60-M63 Disorders of muscles
0.867 0.133 0.000
J98.8 Other specified respiratory disorders
0.866 0.134 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.865 0.135 0.000
Z99.1 Dependence on respirator
0.863 0.137 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.862 0.138 0.000
Chapter I Certain infectious and parasitic diseases
0.860 0.140 0.000
Chapter XXII Codes for special purposes
0.860 0.140 0.000
H57.8 Other specified disorders of eye and adnexa
0.859 0.141 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.859 0.141 0.000
Z58 Problems related to physical environment
0.858 0.142 0.000
M05 Seropositive rheumatoid arthritis
0.856 0.144 0.000
Y52 Agents primarily affecting the cardiovascular system
0.855 0.145 0.000
I45.3 Trifascicular block
0.855 0.145 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.855 0.145 0.000
Z83.5 Family history of eye and ear disorders
0.854 0.146 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.854 0.146 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.853 0.147 0.000
H40-H42 Glaucoma
0.853 0.147 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.852 0.148 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.851 0.149 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.851 0.149 0.000
H54 Blindness and low vision
0.849 0.151 0.000
H04 Disorders of lachrymal system
0.849 0.151 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.848 0.151 0.000
H70 Mastoiditis and related conditions
0.847 0.153 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.844 0.156 0.000
M79.61 Pain in limb (Shoulder region)
0.842 0.157 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.840 0.160 0.000
M79.69 Pain in limb (Site unspecified)
0.838 0.162 0.000
M53 Other dorsopathies, not elsewhere classified
0.838 0.162 0.000
Q05.9 Spina bifida, unspecified
0.838 0.162 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.837 0.163 0.000
T75 Effects of other external causes
0.837 0.163 0.000
M67 Other disorders of synovium and tendon
0.836 0.164 0.000
H73.8 Other specified disorders of tympanic membrane
0.835 0.165 0.000
E20-E35 Disorders of other endocrine glands
0.834 0.166 0.000
T23 Burn and corrosion of wrist and hand
0.833 0.167 0.000
M79.2 Neuralgia and neuritis, unspecified
0.833 0.167 0.000
Z63.4 Disappearance and death of family member
0.832 0.168 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.832 0.168 0.000
M31.3 Wegener's granulomatosis
0.832 0.168 0.000
M20 Acquired deformities of fingers and toes
0.830 0.170 0.000
I20 Angina pectoris
0.829 0.171 0.000
M24.5 Contracture of joint
0.828 0.172 0.000
M91-M94 Chondropathies
0.827 0.173 0.000
I51.9 Heart disease, unspecified
0.827 0.173 0.000
I27 Other pulmonary heart diseases
0.826 0.174 0.000
M54.3 Sciatica
0.826 0.174 0.000
S30.0 Contusion of lower back and pelvis
0.823 0.177 0.000
E65-E68 Obesity and other hyperalimentation
0.823 0.177 0.000
M79.68 Pain in limb (Other)
0.823 0.177 0.000
V20-V29 Motorcycle rider injured in transport accident
0.822 0.178 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.821 0.179 0.000
Z64 Problems related to certain psychosocial circumstances
0.821 0.179 0.000
Y40 Systemic antibiotics
0.821 0.179 0.000
H60-H62 Diseases of external ear
0.820 0.180 0.000
M86-M90 Other osteopathies
0.820 0.180 0.000
Q89 Other congenital malformations, not elsewhere classified
0.819 0.181 0.000
I45.6 Preexcitation syndrome
0.819 0.181 0.000
Y00-Y09 Assault
0.818 0.182 0.000
Z74 Problems related to care-provider dependency
0.817 0.183 0.000
B35-B49 Mycoses
0.816 0.184 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.816 0.184 0.000
I31 Other diseases of pericardium
0.814 0.186 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.814 0.186 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.813 0.187 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.813 0.187 0.000
I51.7 Cardiomegaly
0.812 0.188 0.000
M24.07 Loose body in joint (Ankle and foot)
0.812 0.188 0.000
M20.5 Other deformities of toe(s) (acquired)
0.812 0.188 0.000
J86 Pyothorax
0.812 0.188 0.000
M35.1 Other overlap syndromes
0.812 0.188 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.810 0.190 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.809 0.191 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.807 0.193 0.000
Z98 Other postsurgical states
0.805 0.195 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.805 0.195 0.000
J98.6 Disorders of diaphragm
0.803 0.197 0.000
Z59.8 Other problems relating to housing and economic circumstances
0.803 0.197 0.000
H04.1 Other disorders of lachrymal gland
0.801 0.199 0.000
X49.9 Unspecified place
0.800 0.200 0.000
W50-W64 Exposure to animate mechanical forces
0.800 0.200 0.000
B25-B34 Other viral diseases
0.799 0.201 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.799 0.201 0.000
H43-H45 Disorders of vitreous body and globe
0.799 0.201 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.798 0.202 0.000
H69 Other disorders of Eustachian tube
0.798 0.202 0.000
H54.4 Blindness, one eye
0.798 0.202 0.000
H10 Conjunctivitis
0.798 0.202 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.796 0.204 0.000
G57.6 Lesion of plantar nerve
0.796 0.204 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.795 0.205 0.000
I45.4 Nonspecific intraventricular block
0.795 0.205 0.000
M54.55 Low back pain (Thoracolumbar region)
0.794 0.206 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.793 0.207 0.000
J98.2 Interstitial emphysema
0.792 0.208 0.000
I20.9 Angina pectoris, unspecified
0.792 0.208 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.791 0.209 0.000
Y48.2 Other and unspecified general anaesthetics
0.791 0.209 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.790 0.210 0.000
Z65 Problems related to other psychosocial circumstances
0.789 0.210 0.000
Q07 Other congenital malformations of nervous system
0.789 0.211 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.788 0.212 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.788 0.212 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.788 0.212 0.000
M35.3 Polymyalgia rheumatica
0.787 0.213 0.000
T78.3 Angioneurotic oedema
0.786 0.214 0.000
J84.8 Other specified interstitial pulmonary diseases
0.786 0.214 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.784 0.216 0.000
E66 Obesity
0.784 0.216 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.784 0.216 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.783 0.217 0.000
H01.1 Non-infectious dermatoses of eyelid
0.782 0.218 0.000
M13.0 Polyarthritis, unspecified
0.782 0.218 0.000
Y42.4 Oral contraceptives
0.782 0.218 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.781 0.219 0.000
M43 Other deforming dorsopathies
0.780 0.220 0.000
H57.1 Ocular pain
0.780 0.220 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.778 0.222 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.776 0.224 0.000
I25.3 Aneurysm of heart
0.776 0.224 0.000
T21 Burn and corrosion of trunk
0.775 0.224 0.000
M79.62 Pain in limb (Upper arm)
0.775 0.225 0.000
M79.08 Rheumatism, unspecified (Other)
0.775 0.225 0.000
I27.0 Primary pulmonary hypertension
0.775 0.225 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.774 0.226 0.000
T70 Effects of air pressure and water pressure
0.773 0.227 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.773 0.227 0.000
B37 Candidiasis
0.773 0.227 0.000
Z83.6 Family history of diseases of the respiratory system
0.773 0.227 0.000
I28 Other diseases of pulmonary vessels
0.772 0.228 0.000
M79.1 Myalgia
0.772 0.228 0.000
M62 Other disorders of muscle
0.772 0.228 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.771 0.228 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.771 0.229 0.000
V01-V09 Pedestrian injured in transport accident
0.770 0.230 0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified
0.770 0.230 0.000
E66.9 Obesity, unspecified
0.769 0.231 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.769 0.231 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.769 0.231 0.000
S30.2 Contusion of external genital organs
0.768 0.232 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.767 0.232 0.000
J86.9 Pyothorax without fistula
0.767 0.233 0.000
T00-T07 Injuries involving multiple body regions
0.766 0.234 0.000
M54.54 Low back pain-Thoracic
0.765 0.235 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.765 0.235 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.765 0.235 0.000
X50-X57 Overexertion, travel and privation
0.764 0.236 0.000
M30 Polyarteritis nodosa and related conditions
0.763 0.237 0.000
M80-M85 Disorders of bone density and structure
0.762 0.238 0.000
M79.63 Pain in limb (Forearm)
0.762 0.238 0.000
M79.7 Fibromyalgia
0.761 0.239 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.761 0.239 0.000
W75-W84 Other accidental threats to breathing
0.761 0.239 0.000
E50-E64 Other nutritional deficiencies
0.760 0.240 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.759 0.241 0.000
T18 Foreign body in alimentary tract
0.759 0.241 0.000
Z58.8 Other problems related to physical environment
0.758 0.242 0.000
Q85 Phakomatoses, not elsewhere classified
0.758 0.242 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.757 0.242 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.755 0.245 0.000
G60 Hereditary and idiopathic neuropathy
0.754 0.246 0.000
Y59 Other and unspecified vaccines and biological substances
0.754 0.246 0.000
S50-S59 Injuries to the elbow and forearm
0.753 0.247 0.000
Q89.2 Congenital malformations of other endocrine glands
0.753 0.247 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.753 0.247 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.753 0.247 0.000
S37 Injury of urinary and pelvic organs
0.753 0.247 0.000
I21.9 Acute myocardial infarction, unspecified
0.752 0.248 0.000
Y48.4 Anaesthetic, unspecified
0.751 0.248 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.751 0.249 0.000
J90-J94 Other diseases of pleura
0.751 0.249 0.000
G54 Nerve root and plexus disorders
0.750 0.250 0.000
H66 Suppurative and unspecified otitis media
0.750 0.250 0.000
I45.9 Conduction disorder, unspecified
0.749 0.251 0.000
G57.5 Tarsal tunnel syndrome
0.749 0.251 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.749 0.251 0.000
Y42.2 Antithyroid drugs
0.748 0.251 0.000
X20-X29 Contact with venomous animals and plants
0.748 0.252 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.747 0.252 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.747 0.253 0.000
H40 Glaucoma
0.747 0.253 0.000
H74.1 Adhesive middle ear disease
0.746 0.254 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.746 0.254 0.000
I40 Acute myocarditis
0.745 0.254 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.745 0.255 0.000
H70.9 Mastoiditis, unspecified
0.745 0.255 0.000
M35.8 Other specified systemic involvement of connective tissue
0.745 0.255 0.000
H90-H95 Other disorders of ear
0.744 0.256 0.000
H40.2 Primary angle-closure glaucoma
0.744 0.256 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.744 0.256 0.000
M76 Enthesopathies of lower limb, excluding foot
0.744 0.256 0.000
I95 Hypotension
0.744 0.256 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.743 0.257 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.742 0.258 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.742 0.258 0.000
U89 Agent resistant to other and unspecified antibiotics
0.742 0.258 0.000
M15-M19 Arthrosis
0.741 0.259 0.000
Z59.0 Homelessness
0.741 0.259 0.000
Z82.2 Family history of deafness and hearing loss
0.740 0.260 0.000
Z83.3 Family history of diabetes mellitus
0.739 0.261 0.000
S90-S99 Injuries to the ankle and foot
0.738 0.261 0.000
M79.5 Residual foreign body in soft tissue
0.738 0.262 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.738 0.262 0.000
X58 Exposure to other specified factors
0.738 0.262 0.000
M06.34 Rheumatoid nodule (Hand)
0.737 0.263 0.000
H01.9 Inflammation of eyelid, unspecified
0.737 0.263 0.000
J85 Abscess of lung and mediastinum
0.736 0.264 0.000
T75.4 Effects of electric current
0.736 0.264 0.000
M51.9 Intervertebral disk disorder, unspecified
0.736 0.264 0.000
S14 Injury of nerves and spinal cord at neck level
0.734 0.266 0.000
Z98.1 Arthrodesis status
0.734 0.266 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.733 0.266 0.000
M54.37 Sciatica (Lumbosacral region)
0.733 0.267 0.000
M12 Other specific arthropathies
0.733 0.267 0.000
B34 Viral infection of unspecified site
0.732 0.268 0.000
I11 Hypertensive heart disease
0.732 0.268 0.000
E24 Cushing's syndrome
0.732 0.268 0.000
M77 Other enthesopathies
0.732 0.268 0.000
H10.9 Conjunctivitis, unspecified
0.730 0.270 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.730 0.270 0.000
M24.6 Ankylosis of joint
0.730 0.270 0.000
M06.4 Inflammatory polyarthropathy
0.729 0.270 0.000
M24.56 Contracture of joint (Lower leg)
0.729 0.271 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.729 0.271 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.728 0.272 0.000
Z60 Problems related to social environment
0.728 0.272 0.000
M06.0 Seronegative rheumatoid arthritis
0.728 0.272 0.000
Z71.2 Person consulting for explanation of investigation findings
0.727 0.273 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.727 0.273 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.727 0.273 0.000
M13.94 Arthritis, unspecified (Hand)
0.726 0.274 0.000
E27 Other disorders of adrenal gland
0.726 0.274 0.000
H01.8 Other specified inflammation of eyelid
0.725 0.275 0.000
T17.8 Foreign body in other and multiple parts of respiratory tract
0.725 0.275 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.725 0.275 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.724 0.276 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.724 0.276 0.000
Y57 Other and unspecified drugs and medicaments
0.723 0.276 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.723 0.277 0.000
I95.1 Orthostatic hypotension
0.723 0.277 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.723 0.277 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.723 0.277 0.000
X10-X19 Contact with heat and hot substances
0.722 0.278 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.721 0.279 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.721 0.279 0.000
X45 Accidental poisoning by and exposure to alcohol
0.720 0.280 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.720 0.280 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.719 0.280 0.000
T63 Toxic effect of contact with venomous animals
0.719 0.281 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.718 0.281 0.000
I25.5 Ischaemic cardiomyopathy
0.718 0.282 0.000
V98-V99 Other and unspecified transport accidents
0.718 0.282 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.718 0.282 0.000
M79.9 Soft tissue disorder, unspecified
0.718 0.282 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.717 0.283 0.000
H04.8 Other disorders of lachrymal system
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
M51.3 Other specified intervertebral disk degeneration
0.717 0.283 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.717 0.283 0.000
Y58 Bacterial vaccines
0.717 0.283 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.717 0.283 0.000
S12 Fracture of neck
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.715 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
M35.2 Behcet's disease
0.715 0.285 0.000
E28 Ovarian dysfunction
0.715 0.285 0.000
M24.02 Loose body in joint (Upper arm)
0.714 0.286 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.713 0.286 0.000
Q05.4 Unspecified spina bifida with hydrocephalus
0.713 0.287 0.000
I45.0 Right fascicular block
0.713 0.287 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.713 0.287 0.000
M54.27 Cervicalgia-Lumbosacral
0.713 0.287 0.000
M54.26 Cervicalgia-Lumbar
0.713 0.287 0.000
M54.25 Cervicalgia-Thoracolumbar
0.713 0.287 0.000
M54.24 Cervicalgia-Thoracic
0.713 0.287 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.713 0.287 0.000
M54.20 Cervicalgia-Mult site
0.713 0.287 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.713 0.287 0.000
M35.0 Sicca syndrome [Sjogren]
0.713 0.287 0.000
M81 Osteoporosis without pathological fracture
0.713 0.287 0.000
I25.6 Silent myocardial ischaemia
0.712 0.288 0.000
H74.4 Polyp of middle ear
0.712 0.288 0.000
M51.4 Schmorl's nodes
0.711 0.288 0.000
M67.8 Other specified disorders of synovium and tendon
0.711 0.289 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.711 0.289 0.000
Z74.2 Need for assistance at home and no other household member able to render care
0.710 0.290 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.710 0.290 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.710 0.290 0.000
I46.1 Sudden cardiac death, so described
0.710 0.290 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.710 0.290 0.000
H68 Eustachian salpingitis and obstruction
0.710 0.290 0.000
H67 Otitis media in diseases classified elsewhere
0.710 0.290 0.000
Q35-Q37 Cleft lip and cleft palate
0.710 0.290 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.710 0.290 0.000
J96 Respiratory failure, not elsewhere classified
0.708 0.292 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.708 0.292 0.000
H00 Hordeolum and chalazion
0.708 0.292 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.708 0.292 0.000
W20-W49 Exposure to inanimate mechanical forces
0.708 0.292 0.000
G57.0 Lesion of sciatic nerve
0.708 0.292 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.707 0.293 0.000
M79.3 Panniculitis, unspecified
0.706 0.294 0.000
G30-G32 Other degenerative diseases of the nervous system
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.706 0.294 0.000
Z62 Other problems related to upbringing
0.706 0.294 0.000
Z61 Problems related to negative life events in childhood
0.706 0.294 0.000
Z55 Problems related to education and literacy
0.706 0.294 0.000
J98.3 Compensatory emphysema
0.705 0.295 0.000
H16 Keratitis
0.704 0.296 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.704 0.296 0.000
T19 Foreign body in genito-urinary tract
0.704 0.296 0.000
T15 Foreign body on external eye
0.704 0.296 0.000
Z64.0 Problems related to unwanted pregnancy
0.703 0.297 0.000
G90-G99 Other disorders of the nervous system
0.703 0.297 0.000
M24.04 Loose body in joint (Hand)
0.703 0.297 0.000
M89 Other disorders of bone
0.703 0.297 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.702 0.297 0.000
Z99.4 Dependence on artificial heart
0.702 0.297 0.000
Z99.0 Dependence on aspirator
0.702 0.297 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.702 0.298 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.702 0.298 0.000
T74 Maltreatment syndromes
0.701 0.299 0.000
T73 Effects of other deprivation
0.701 0.299 0.000
T69 Other effects of reduced temperature
0.701 0.299 0.000
T67 Effects of heat and light
0.701 0.299 0.000
T71 Asphyxiation
0.701 0.299 0.000
T66 Unspecified effects of radiation
0.701 0.299 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.701 0.299 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.701 0.299 0.000
B34.9 Viral infection, unspecified
0.701 0.299 0.000
M40 Kyphosis and lordosis
0.700 0.299 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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