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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs41306231
log Bayes Factor = 22.7252
Chromosome 1   position 200,801,935  (GRCh37) Explore rs41306231 on Ensembl!
Variant rs41306231 is part of Cluster X0146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Z92 Personal history of medical treatment
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.992 0.008 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.991 0.009 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.988 0.012 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.986 0.014 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.985 0.015 0.000
N20-N23 Urolithiasis
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
M50-M54 Other dorsopathies
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.978 0.022 0.000
Z51 Other medical care
0.972 0.028 0.000
N23 Unspecified renal colic
0.970 0.030 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.967 0.033 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.966 0.034 0.000
R42 Dizziness and giddiness
0.965 0.035 0.000
Z45 Adjustment and management of implanted device
0.964 0.036 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.963 0.037 0.000
M20-M25 Other joint disorders
0.963 0.037 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.959 0.041 0.000
Chapter V Mental and behavioural disorders
0.959 0.041 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.956 0.044 0.000
I60-I69 Cerebrovascular diseases
0.954 0.046 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.952 0.048 0.000
N10-N16 Renal tubulo-interstitial diseases
0.952 0.048 0.000
R00 Abnormalities of heart beat
0.943 0.057 0.000
M54 Dorsalgia
0.941 0.059 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.938 0.062 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.933 0.067 0.000
C78.7 Secondary malignant neoplasm of liver
0.932 0.068 0.000
N60-N64 Disorders of breast
0.928 0.072 0.000
S80-S89 Injuries to the knee and lower leg
0.927 0.073 0.000
Z92.3 Personal history of irradiation
0.923 0.077 0.000
G40-G47 Episodic and paroxysmal disorders
0.921 0.079 0.000
Z50 Care involving use of rehabilitation procedures
0.920 0.080 0.000
F30-F39 Mood [affective] disorders
0.915 0.085 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.915 0.085 0.000
R00.2 Palpitations
0.911 0.089 0.000
Chapter VIII Diseases of the ear and mastoid process
0.910 0.090 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.909 0.091 0.000
I51 Complications and ill-defined descriptions of heart disease
0.908 0.092 0.000
I95 Hypotension
0.908 0.092 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.904 0.096 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.904 0.096 0.000
M50 Cervical disk disorders
0.902 0.097 0.000
Z95.0 Presence of cardiac pacemaker
0.900 0.100 0.000
I73 Other peripheral vascular diseases
0.896 0.104 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.895 0.105 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.894 0.106 0.000
M35 Other systemic involvement of connective tissue
0.888 0.112 0.000
S00-S09 Injuries to the head
0.888 0.112 0.000
M65-M68 Disorders of synovium and tendon
0.886 0.114 0.000
Z51.1 Chemotherapy session for neoplasm
0.885 0.115 0.000
N13 Obstructive and reflux uropathy
0.884 0.116 0.000
C51-C58 Malignant neoplasms of female genital organs
0.884 0.116 0.000
R07 Pain in throat and chest
0.883 0.117 0.000
G40 Epilepsy
0.882 0.118 0.000
C78.0 Secondary malignant neoplasm of lung
0.881 0.119 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.881 0.119 0.000
C77.5 Intrapelvic lymph nodes
0.879 0.121 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.878 0.122 0.000
M20 Acquired deformities of fingers and toes
0.875 0.125 0.000
D70 Agranulocytosis
0.874 0.126 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.873 0.127 0.000
Z48 Other surgical follow-up care
0.873 0.127 0.000
R07.4 Chest pain, unspecified
0.869 0.131 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.867 0.133 0.000
Z51.2 Other chemotherapy
0.866 0.134 0.000
C77.2 Intra-abdominal lymph nodes
0.865 0.135 0.000
M50.1 Cervical disk disorder with radiculopathy
0.864 0.136 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.864 0.136 0.000
N40-N51 Diseases of male genital organs
0.863 0.137 0.000
F32 Depressive episode
0.860 0.140 0.000
S20-S29 Injuries to the thorax
0.859 0.141 0.000
I63 Cerebral infarction
0.859 0.141 0.000
G90-G99 Other disorders of the nervous system
0.859 0.141 0.000
I45 Other conduction disorders
0.859 0.141 0.000
R00.0 Tachycardia, unspecified
0.858 0.142 0.000
M54.3 Sciatica
0.857 0.143 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.856 0.144 0.000
Z46 Fitting and adjustment of other devices
0.856 0.144 0.000
I42 Cardiomyopathy
0.856 0.144 0.000
Chapter I Certain infectious and parasitic diseases
0.856 0.144 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.853 0.147 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.853 0.147 0.000
I51.7 Cardiomegaly
0.850 0.150 0.000
N60 Benign mammary dysplasia
0.847 0.153 0.000
I44 Atrioventricular and left bundle-branch block
0.846 0.154 0.000
Z45.8 Adjustment and management of other implanted devices
0.846 0.154 0.000
Z51.5 Palliative care
0.843 0.157 0.000
G40.9 Epilepsy, unspecified
0.843 0.157 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.842 0.158 0.000
T79-T79 Certain early complications of trauma
0.838 0.162 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.837 0.163 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.836 0.164 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.835 0.165 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.834 0.166 0.000
Z51.8 Other specified medical care
0.832 0.168 0.000
S60-S69 Injuries to the wrist and hand
0.831 0.169 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.830 0.170 0.000
M35.3 Polymyalgia rheumatica
0.829 0.171 0.000
N30-N39 Other diseases of urinary system
0.829 0.171 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.828 0.172 0.000
Z40 Prophylactic surgery
0.827 0.173 0.000
C15-C26 Malignant neoplasms of digestive organs
0.826 0.174 0.000
I67 Other cerebrovascular diseases
0.825 0.175 0.000
Z96 Presence of other functional implants
0.822 0.178 0.000
Z42 Follow-up care involving plastic surgery
0.821 0.179 0.000
Y86 Sequelae of other accidents
0.821 0.179 0.000
R45 Symptoms and signs involving emotional state
0.820 0.180 0.000
M54.4 Lumbago with sciatica
0.819 0.181 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.819 0.181 0.000
W00-W19 Falls
0.817 0.183 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.815 0.185 0.000
Z94 Transplanted organ and tissue status
0.813 0.186 0.000
I95.9 Hypotension, unspecified
0.813 0.187 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.811 0.189 0.000
N73 Other female pelvic inflammatory diseases
0.810 0.190 0.000
N20 Calculus of kidney and ureter
0.809 0.191 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.803 0.197 0.000
I05-I09 Chronic rheumatic heart diseases
0.802 0.198 0.000
M54.39 Sciatica (Site unspecified)
0.800 0.200 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.800 0.200 0.000
I31 Other diseases of pericardium
0.800 0.200 0.000
I33 Acute and subacute endocarditis
0.799 0.201 0.000
Z93 Artificial opening status
0.798 0.202 0.000
I73.0 Raynaud's syndrome
0.797 0.203 0.000
I95.1 Orthostatic hypotension
0.797 0.203 0.000
G93 Other disorders of brain
0.796 0.204 0.000
F32.9 Depressive episode, unspecified
0.795 0.205 0.000
M65 Synovitis and tenosynovitis
0.794 0.206 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.794 0.206 0.000
I38 Endocarditis, valve unspecified
0.794 0.206 0.000
I73.9 Peripheral vascular disease, unspecified
0.793 0.207 0.000
H80-H83 Diseases of inner ear
0.793 0.207 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.793 0.207 0.000
N62 Hypertrophy of breast
0.792 0.208 0.000
M21 Other acquired deformities of limbs
0.791 0.209 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.787 0.213 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.787 0.213 0.000
C85.1 B-cell lymphoma, unspecified
0.786 0.214 0.000
S00 Superficial injury of head
0.785 0.215 0.000
S82 Fracture of lower leg, including ankle
0.785 0.215 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.784 0.216 0.000
I99 Other and unspecified disorders of circulatory system
0.783 0.217 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.783 0.217 0.000
C60-C63 Malignant neoplasms of male genital organs
0.782 0.218 0.000
R47-R49 Symptoms and signs involving speech and voice
0.781 0.218 0.000
Z97 Presence of other devices
0.781 0.219 0.000
Chapter XXII Codes for special purposes
0.778 0.222 0.000
Chapter X Diseases of the respiratory system
0.778 0.222 0.000
D72 Other disorders of white blood cells
0.777 0.223 0.000
H65-H75 Diseases of middle ear and mastoid
0.776 0.224 0.000
B95-B98 Bacterial, viral and other infectious agents
0.776 0.224 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.774 0.226 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.774 0.226 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.774 0.226 0.000
I35 Nonrheumatic aortic valve disorders
0.773 0.227 0.000
Z95.4 Presence of other heart-valve replacement
0.772 0.227 0.000
Z92.8 Personal history of other medical treatment
0.771 0.229 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.770 0.230 0.000
M40-M43 Deforming dorsopathies
0.769 0.231 0.000
X60-X84 Intentional self-harm
0.769 0.231 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.769 0.231 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.768 0.232 0.000
W20-W49 Exposure to inanimate mechanical forces
0.767 0.233 0.000
N43 Hydrocele and spermatocele
0.766 0.234 0.000
S80 Superficial injury of lower leg
0.765 0.235 0.000
Z99.3 Dependence on wheelchair
0.763 0.237 0.000
C56 Malignant neoplasm of ovary
0.763 0.237 0.000
Z47 Other orthopaedic follow-up care
0.763 0.237 0.000
M20.2 Hallux rigidus
0.762 0.238 0.000
D00-D09 In situ neoplasms
0.762 0.238 0.000
I69 Sequelae of cerebrovascular disease
0.762 0.238 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.761 0.239 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.761 0.239 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.761 0.239 0.000
C77.3 Axillary and upper limb lymph nodes
0.758 0.242 0.000
F33 Recurrent depressive disorder
0.757 0.243 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.756 0.244 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.753 0.247 0.000
C18 Malignant neoplasm of colon
0.751 0.249 0.000
I20-I25 Ischaemic heart diseases
0.751 0.249 0.000
I78 Diseases of capillaries
0.750 0.250 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.750 0.250 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.749 0.251 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.749 0.251 0.000
Z75 Problems related to medical facilities and other health care
0.748 0.252 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.747 0.253 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.743 0.257 0.000
C92 Myeloid leukaemia
0.742 0.258 0.000
C77.4 Inguinal and lower limb lymph nodes
0.742 0.258 0.000
Z48.0 Attention to surgical dressings and sutures
0.742 0.258 0.000
R02 Gangrene, not elsewhere classified
0.741 0.259 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.741 0.259 0.000
F99-F99 Unspecified mental disorder
0.741 0.259 0.000
I42.9 Cardiomyopathy, unspecified
0.740 0.260 0.000
Z50.8 Care involving use of rehabilitation procedures
0.739 0.260 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.738 0.262 0.000
I47 Paroxysmal tachycardia
0.738 0.262 0.000
I34 Nonrheumatic mitral valve disorders
0.738 0.262 0.000
I80 Phlebitis and thrombophlebitis
0.738 0.262 0.000
I62 Other nontraumatic intracranial haemorrhage
0.738 0.262 0.000
R26 Abnormalities of gait and mobility
0.737 0.263 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.736 0.264 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.736 0.264 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.736 0.264 0.000
Z63 Other problems related to primary support group, including family circumstances
0.735 0.265 0.000
Z96.0 Presence of urogenital implants
0.733 0.267 0.000
Z85 Personal history of malignant neoplasm
0.733 0.267 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.732 0.267 0.000
I74 Arterial embolism and thrombosis
0.732 0.268 0.000
J30-J39 Other diseases of upper respiratory tract
0.732 0.268 0.000
N10 Acute tubulo-interstitial nephritis
0.732 0.268 0.000
I71 Aortic aneurysm and dissection
0.731 0.269 0.000
T39.1 4-Aminophenol derivatives
0.731 0.269 0.000
N35 Urethral stricture
0.729 0.271 0.000
N73.6 Female pelvic peritoneal adhesions
0.728 0.272 0.000
M20.4 Other hammer toe(s) (acquired)
0.728 0.272 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.728 0.272 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.728 0.272 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.272 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.727 0.273 0.000
Z72 Problems related to lifestyle
0.727 0.273 0.000
I20 Angina pectoris
0.727 0.273 0.000
M20.1 Hallux valgus (acquired)
0.726 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.726 0.274 0.000
M31 Other necrotising vasculopathies
0.726 0.274 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.725 0.275 0.000
G41 Status epilepticus
0.725 0.275 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.725 0.275 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.724 0.276 0.000
C77.0 Lymph nodes of head, face and neck
0.724 0.276 0.000
M65.3 Trigger finger
0.723 0.277 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.723 0.277 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.723 0.277 0.000
Z94.8 Other transplanted organ and tissue status
0.722 0.278 0.000
Z51.3 Blood transfusion without reported diagnosis
0.721 0.279 0.000
I67.9 Cerebrovascular disease, unspecified
0.721 0.279 0.000
M54.1 Radiculopathy
0.721 0.279 0.000
I67.1 Cerebral aneurysm, nonruptured
0.720 0.280 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.720 0.280 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.720 0.280 0.000
I45.1 Other and unspecified right bundle-branch block
0.720 0.280 0.000
I60 Subarachnoid haemorrhage
0.720 0.280 0.000
H60-H62 Diseases of external ear
0.719 0.281 0.000
S70-S79 Injuries to the hip and thigh
0.719 0.281 0.000
N61 Inflammatory disorders of breast
0.719 0.281 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.718 0.282 0.000
I44.1 Atrioventricular block, second degree
0.718 0.282 0.000
I63.9 Cerebral infarction, unspecified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z52 Donors of organs and tissues
0.717 0.283 0.000
Z49 Care involving dialysis
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Z89 Acquired absence of limb
0.716 0.283 0.000
Z84 Family history of other conditions
0.716 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.283 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.716 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.716 0.283 0.000
Z92.5 Personal history of rehabilitation measures
0.716 0.283 0.000
Z92.0 Personal history of contraception
0.716 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
C71 Malignant neoplasm of brain
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
F20 Schizophrenia
0.714 0.286 0.000
M25 Other joint disorders, not elsewhere classified
0.713 0.287 0.000
M54.9 Dorsalgia, unspecified
0.712 0.288 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.712 0.288 0.000
D75 Other diseases of blood and blood-forming organs
0.712 0.288 0.000
I42.2 Other hypertrophic cardiomyopathy
0.712 0.288 0.000
I52 Other heart disorders in diseases classified elsewhere
0.711 0.288 0.000
I48 Atrial fibrillation and flutter
0.711 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.711 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.711 0.288 0.000
I40 Acute myocarditis
0.711 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.711 0.288 0.000
I37 Pulmonary valve disorders
0.711 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.711 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.711 0.288 0.000
I30 Acute pericarditis
0.711 0.288 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.711 0.289 0.000
N20.1 Calculus of ureter
0.711 0.289 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.710 0.290 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.710 0.290 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.710 0.290 0.000
I61 Intracerebral haemorrhage
0.710 0.290 0.000
I20.9 Angina pectoris, unspecified
0.710 0.290 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.708 0.292 0.000
S50-S59 Injuries to the elbow and forearm
0.708 0.292 0.000
M70-M79 Other soft tissue disorders
0.707 0.293 0.000
R46 Symptoms and signs involving appearance and behaviour
0.707 0.293 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.707 0.293 0.000
R43 Disturbances of smell and taste
0.707 0.293 0.000
Z80 Family history of malignant neoplasm
0.706 0.294 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.706 0.294 0.000
S40-S49 Injuries to the shoulder and upper arm
0.706 0.294 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.706 0.294 0.000
C90.0 Multiple myeloma
0.705 0.295 0.000
M54.5 Low back pain
0.704 0.296 0.000
M86-M90 Other osteopathies
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V20-V29 Motorcycle rider injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
A30-A49 Other bacterial diseases
0.702 0.297 0.000
M53 Other dorsopathies, not elsewhere classified
0.702 0.298 0.000
R45.8 Other symptoms and signs involving emotional state
0.701 0.299 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.701 0.299 0.000
Y88 Sequelae of surgical and medical care as external cause
0.701 0.299 0.000
N13.3 Other and unspecified hydronephrosis
0.701 0.299 0.000
R50-R69 General symptoms and signs
0.700 0.300 0.000
Z45.1 Adjustment and management of infusion pump
0.700 0.300 0.000
N25-N29 Other disorders of kidney and ureter
0.699 0.301 0.000
I31.9 Disease of pericardium, unspecified
0.699 0.301 0.000
S05 Injury of eye and orbit
0.699 0.301 0.000
S02 Fracture of skull and facial bones
0.698 0.302 0.000
Z48.9 Surgical follow-up care, unspecified
0.697 0.303 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.697 0.303 0.000
N43.3 Hydrocele, unspecified
0.697 0.303 0.000
Z51.9 Medical care, unspecified
0.697 0.303 0.000
Z51.6 Desensitisation to allergens
0.697 0.303 0.000
N48 Other disorders of penis
0.697 0.303 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.696 0.303 0.000
N76 Other inflammation of vagina and vulva
0.696 0.304 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.695 0.305 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.694 0.306 0.000
C77.8 Lymph nodes of multiple regions
0.693 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.693 0.307 0.000
M66 Spontaneous rupture of synovium and tendon
0.693 0.307 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.693 0.307 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.693 0.307 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.693 0.307 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.693 0.307 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.693 0.307 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.693 0.307 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.693 0.307 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
T36 Poisoning by systemic antibiotics
0.693 0.307 0.000
N60.8 Other benign mammary dysplasias
0.691 0.309 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.691 0.309 0.000
Z45.3 Adjustment and management of implanted hearing device
0.691 0.309 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.691 0.309 0.000
I45.9 Conduction disorder, unspecified
0.691 0.309 0.000
C80 Malignant neoplasm without specification of site
0.691 0.309 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.690 0.310 0.000
M34 Systemic sclerosis
0.690 0.310 0.000
M33 Dermatopolymyositis
0.690 0.310 0.000
M32 Systemic lupus erythematosus
0.690 0.310 0.000
M30 Polyarteritis nodosa and related conditions
0.690 0.310 0.000
Q00-Q07 Congenital malformations of the nervous system
0.688 0.312 0.000
Y85 Sequelae of transport accidents
0.688 0.312 0.000
N60.1 Diffuse cystic mastopathy
0.688 0.312 0.000
Z96.8 Presence of other specified functional implants
0.688 0.312 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.688 0.312 0.000
C95 Leukaemia of unspecified cell type
0.688 0.312 0.000
C94 Other leukaemias of specified cell type
0.688 0.312 0.000
C93 Monocytic leukaemia
0.688 0.312 0.000
C88 Malignant immunoproliferative diseases
0.688 0.312 0.000
C86 Other specified types of T/NK-cell lymphoma
0.688 0.312 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.688 0.312 0.000
C81 Hodgkin's disease
0.688 0.312 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.688 0.312 0.000
F80-F89 Disorders of psychological development
0.688 0.312 0.000
F70-F79 Mental retardation
0.688 0.312 0.000
F60-F69 Disorders of adult personality and behaviour
0.688 0.312 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.688 0.312 0.000
Z45.2 Adjustment and management of vascular access device
0.687 0.313 0.000
R50 Fever of unknown origin
0.687 0.313 0.000
Z91.5 Personal history of self-harm
0.687 0.313 0.000
S68 Traumatic amputation of wrist and hand
0.687 0.313 0.000
C15 Malignant neoplasm of oesophagus
0.687 0.313 0.000
I95.2 Hypotension due to drugs
0.686 0.314 0.000
N30 Cystitis
0.686 0.314 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.686 0.314 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.686 0.314 0.000
N41 Inflammatory diseases of prostate
0.685 0.315 0.000
G51 Facial nerve disorders
0.685 0.315 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.685 0.315 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.684 0.316 0.000
H81 Disorders of vestibular function
0.684 0.316 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.684 0.316 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.684 0.316 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.684 0.316 0.000
Z40.8 Other prophylactic surgery
0.684 0.316 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.684 0.316 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.683 0.317 0.000
I72 Other aneurysm
0.683 0.317 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.682 0.317 0.000
N15 Other renal tubulo-interstitial diseases
0.682 0.317 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.682 0.317 0.000
N11 Chronic tubulo-interstitial nephritis
0.682 0.317 0.000
N60.0 Solitary cyst of breast
0.682 0.318 0.000
H73 Other disorders of tympanic membrane
0.682 0.318 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.681 0.319 0.000
Z41 Procedures for purposes other than remedying health state
0.681 0.319 0.000
I51.9 Heart disease, unspecified
0.680 0.320 0.000
R50.9 Fever, unspecified
0.680 0.320 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.680 0.320 0.000
Z95.2 Presence of prosthetic heart valve
0.679 0.321 0.000
S09 Other and unspecified injuries of head
0.679 0.321 0.000
D72.8 Other specified disorders of white blood cells
0.678 0.322 0.000
I86 Varicose veins of other sites
0.678 0.322 0.000
I49 Other cardiac arrhythmias
0.677 0.323 0.000
Z60 Problems related to social environment
0.677 0.323 0.000
I07 Rheumatic tricuspid valve diseases
0.676 0.323 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.676 0.324 0.000
N00-N08 Glomerular diseases
0.676 0.324 0.000
F23 Acute and transient psychotic disorders
0.675 0.324 0.000
S00.0 Superficial injury of scalp
0.675 0.325 0.000
N21 Calculus of lower urinary tract
0.675 0.325 0.000
M54.8 Other dorsalgia
0.675 0.325 0.000
M54.6 Pain in thoracic spine
0.675 0.325 0.000
M54.0 Panniculitis affecting regions of neck and back
0.675 0.325 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.674 0.325 0.000
F31 Bipolar affective disorder
0.674 0.326 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.673 0.327 0.000
F22 Persistent delusional disorders
0.673 0.327 0.000
D55-D59 Haemolytic anaemias
0.672 0.327 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.672 0.327 0.000
M65.34 Trigger finger-Hand
0.672 0.328 0.000
Z22 Carrier of infectious disease
0.672 0.328 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.672 0.328 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.671 0.329 0.000
Z95.3 Presence of xenogenic heart valve
0.670 0.330 0.000
G93.3 Postviral fatigue syndrome
0.670 0.330 0.000
I44.7 Left bundle-branch block, unspecified
0.670 0.330 0.000
R06 Abnormalities of breathing
0.670 0.330 0.000
N45 Orchitis and epididymitis
0.670 0.330 0.000
W07 Fall involving chair
0.670 0.330 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.670 0.330 0.000
M22 Disorders of patella
0.669 0.331 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.669 0.331 0.000
N42 Other disorders of prostate
0.669 0.331 0.000
T93 Sequelae of injuries of lower limb
0.669 0.331 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.669 0.331 0.000
Z57 Occupational exposure to risk-factors
0.668 0.331 0.000
D73 Diseases of spleen
0.668 0.332 0.000
C77.1 Intrathoracic lymph nodes
0.668 0.332 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.668 0.332 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.668 0.332 0.000
R40 Somnolence, stupor and coma
0.667 0.333 0.000
G30-G32 Other degenerative diseases of the nervous system
0.667 0.333 0.000
C18.7 Sigmoid colon
0.667 0.333 0.000
Z72.1 Alcohol use
0.667 0.333 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.665 0.334 0.000
T43.2 Other and unspecified antidepressants
0.665 0.335 0.000
Z73 Problems related to life-management difficulty
0.665 0.335 0.000
S89 Other and unspecified injuries of lower leg
0.664 0.335 0.000
S88 Traumatic amputation of lower leg
0.664 0.335 0.000
S87 Crushing injury of lower leg
0.664 0.335 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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