TreeWAS – Variant ID: rs41308401

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
E10-E14 Diabetes mellitus	0.999	0.001
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001
E10 Insulin-dependent diabetes mellitus	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
I25.1 Atherosclerotic heart disease	0.998	0.002
I25 Chronic ischaemic heart disease	0.997	0.003
Chapter VII Diseases of the eye and adnexa	0.993	0.007
I20-I25 Ischaemic heart diseases	0.988	0.012
Chapter IX Diseases of the circulatory system	0.988	0.012
H30-H36 Disorders of choroid and retina	0.987	0.013
S40-S49 Injuries to the shoulder and upper arm	0.973	0.027
H36 Retinal disorders in diseases classified elsewhere	0.969	0.031
E10.3 With ophthalmic complications	0.959	0.041
I05-I09 Chronic rheumatic heart diseases	0.959	0.041
E14 Unspecified diabetes mellitus	0.956	0.044
H36.0 Diabetic retinopathy	0.955	0.045
Chapter XII Diseases of the skin and subcutaneous tissue	0.954	0.046
I08 Multiple valve diseases	0.943	0.057
E10.9 Without complications	0.943	0.057
S42 Fracture of shoulder and upper arm	0.942	0.058
Chapter XV Pregnancy, childbirth and the puerperium	0.942	0.058
S50-S59 Injuries to the elbow and forearm	0.935	0.065
I25.9 Chronic ischaemic heart disease, unspecified	0.935	0.065
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.925	0.075
Chapter XX External causes of morbidity and mortality	0.922	0.078
L80-L99 Other disorders of the skin and subcutaneous tissue	0.921	0.079
E14.3 With ophthalmic complications	0.920	0.080
L90 Atrophic disorders of skin	0.906	0.094
E11 Non-insulin-dependent diabetes mellitus	0.906	0.094
Chapter VI Diseases of the nervous system	0.906	0.094
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.903	0.097
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.900	0.100
Chapter V Mental and behavioural disorders	0.899	0.101
L90.5 Scar conditions and fibrosis of skin	0.898	0.102
H35 Other retinal disorders	0.896	0.104
I25.8 Other forms of chronic ischaemic heart disease	0.896	0.104
S20-S29 Injuries to the thorax	0.894	0.106
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.892	0.108
G20-G26 Extrapyramidal and movement disorders	0.884	0.116
S42.1 Fracture of scapula	0.883	0.116
H02 Other disorders of eyelid	0.883	0.117
E65-E68 Obesity and other hyperalimentation	0.880	0.120
I25.3 Aneurysm of heart	0.879	0.121
G20 Parkinson's disease	0.877	0.123
L50-L54 Urticaria and erythema	0.872	0.128
S52 Fracture of forearm	0.861	0.139
I25.5 Ischaemic cardiomyopathy	0.861	0.139
H02.9 Disorder of eyelid, unspecified	0.860	0.140
S10-S19 Injuries to the neck	0.857	0.143
Chapter X Diseases of the respiratory system	0.856	0.144
O20-O29 Other maternal disorders predominantly related to pregnancy	0.854	0.146
O94-O99 Other obstetric conditions, not elsewhere classified	0.854	0.146
I08.8 Other multiple valve diseases	0.853	0.147
H34 Retinal vascular occlusions	0.848	0.152
L97 Ulcer of lower limb, not elsewhere classified	0.846	0.154
S42.10 Fracture of scapula (closed)	0.842	0.158
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.841	0.159
S90-S99 Injuries to the ankle and foot	0.840	0.160
E10.4 With neurological complications	0.839	0.161
S42.2 Fracture of upper end of humerus	0.838	0.162
L81 Other disorders of pigmentation	0.836	0.164
O60-O75 Complications of labour and delivery	0.835	0.165
E11.1 With ketoacidosis	0.835	0.165
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.831	0.169
Chapter I Certain infectious and parasitic diseases	0.831	0.169
E10.1 With ketoacidosis	0.829	0.171
H55-H59 Other disorders of eye and adnexa	0.826	0.174
Q20-Q28 Congenital malformations of the circulatory system	0.823	0.177
E10.5 With peripheral circulatory complications	0.819	0.181
O26 Maternal care for other conditions predominantly related to pregnancy	0.819	0.181
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.815	0.185
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.815	0.185
G30-G32 Other degenerative diseases of the nervous system	0.806	0.194
H20 Iridocyclitis	0.801	0.199
I08.1 Disorders of both mitral and tricuspid valves	0.796	0.204
T00-T07 Injuries involving multiple body regions	0.796	0.204
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.792	0.208
O26.8 Other specified pregnancy-related conditions	0.792	0.208
S41 Open wound of shoulder and upper arm	0.791	0.209
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.791	0.209
H35.0 Background retinopathy and retinal vascular changes	0.791	0.209
S52.0 Fracture of upper end of ulna	0.789	0.211
E14.6 With other specified complications	0.788	0.212
H46-H48 Disorders of optic nerve and visual pathways	0.784	0.216
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.782	0.218
E10.0 With coma	0.779	0.221
Chapter XXII Codes for special purposes	0.778	0.222
X50-X57 Overexertion, travel and privation	0.773	0.227
T15-T19 Effects of foreign body entering through natural orifice	0.772	0.228
H02.0 Entropion and trichiasis of eyelid	0.771	0.229
I08.2 Disorders of both aortic and tricuspid valves	0.770	0.230
J95-J99 Other diseases of the respiratory system	0.769	0.231
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.767	0.233
Q00-Q07 Congenital malformations of the nervous system	0.767	0.233
S50 Superficial injury of forearm	0.766	0.234
T20-T25 Burns and corrosions of external body surface, specified by site	0.766	0.234
L53 Other erythematous conditions	0.766	0.234
S70-S79 Injuries to the hip and thigh	0.765	0.234
S42.20 Fracture of upper end of humerus (closed)	0.764	0.236
H34.2 Other retinal artery occlusions	0.764	0.236
A00-A09 Intestinal infectious diseases	0.761	0.239
S54 Injury of nerves at forearm level	0.759	0.241
L81.4 Other melanin hyperpigmentation	0.759	0.241
S42.3 Fracture of shaft of humerus	0.756	0.244
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.755	0.245
H35.9 Retinal disorder, unspecified	0.755	0.245
L92 Granulomatous disorders of skin and subcutaneous tissue	0.754	0.246
L20-L30 Dermatitis and eczema	0.751	0.249
O64 Obstructed labour due to malposition and malpresentation of foetus	0.750	0.250
O75 Other complications of labour and delivery, not elsewhere classified	0.748	0.252
E66 Obesity	0.747	0.253
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.747	0.253
F30-F39 Mood [affective] disorders	0.747	0.253
H21 Other disorders of iris and ciliary body	0.745	0.255
Q21 Congenital malformations of cardiac septa	0.741	0.259
Y60-Y69 Misadventures to patients during surgical and medical care	0.739	0.261
S52.00 Fracture of upper end of ulna (closed)	0.738	0.262
E11.4 With neurological complications	0.738	0.262
S29 Other and unspecified injuries of thorax	0.738	0.262
L50 Urticaria	0.738	0.262
F22 Persistent delusional disorders	0.738	0.262
H25-H28 Disorders of lens	0.737	0.263
E11.3 With ophthalmic complications	0.736	0.264
S22 Fracture of rib(s), sternum and thoracic spine	0.732	0.268
W00-W19 Falls	0.730	0.270
H35.5 Hereditary retinal dystrophy	0.730	0.270
E16 Other disorders of pancreatic internal secretion	0.728	0.272
E10.2 With renal complications	0.728	0.272
S27 Injury of other and unspecified intrathoracic organs	0.725	0.275
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.724	0.276
W50-W64 Exposure to animate mechanical forces	0.722	0.278
E65 Localised adiposity	0.721	0.279
O85-O92 Complications predominantly related to the puerperium	0.720	0.280
G70-G73 Diseases of myoneural junction and muscle	0.720	0.280
E13 Other specified diabetes mellitus	0.719	0.281
H31 Other disorders of choroid	0.718	0.282
X40-X49 Accidental poisoning by and exposure to noxious substances	0.718	0.282
H35.7 Separation of retinal layers	0.718	0.282
S52.5 Fracture of lower end of radius	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
W20-W49 Exposure to inanimate mechanical forces	0.716	0.284
E10.8 With unspecified complications	0.715	0.285
E10.7 With multiple complications	0.715	0.285
E10.6 With other specified complications	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
Q38-Q45 Other congenital malformations of the digestive system	0.715	0.285
I25.6 Silent myocardial ischaemia	0.715	0.285
I25.4 Coronary artery aneurysm	0.715	0.285
I25.0 Atherosclerotic cardiovascular disease, so described	0.715	0.285
S92 Fracture of foot, except ankle	0.711	0.289
E11.5 With peripheral circulatory complications	0.711	0.289
S46 Injury of muscle and tendon at shoulder and upper arm level	0.711	0.289
H35.2 Other proliferative retinopathy	0.711	0.289
H02.4 Ptosis of eyelid	0.710	0.290
I23 Certain current complications following acute myocardial infarction	0.709	0.291
H01 Other inflammation of eyelid	0.709	0.291
I00-I02 Acute rheumatic fever	0.708	0.292
H32 Chorioretinal disorders in diseases classified elsewhere	0.708	0.292
H30 Chorioretinal inflammation	0.708	0.292
V40-V49 Car occupant injured in transport accident	0.707	0.293
G63 Polyneuropathy in diseases classified elsewhere	0.707	0.293
T79-T79 Certain early complications of trauma	0.706	0.294
X60-X84 Intentional self-harm	0.706	0.294
B25-B34 Other viral diseases	0.705	0.295
L93 Lupus erythematosus	0.705	0.295
H03 Disorders of eyelid in diseases classified elsewhere	0.703	0.297
V10-V19 Pedal cyclist injured in transport accident	0.702	0.298
T66-T78 Other and unspecified effects of external causes	0.702	0.298
J60-J70 Lung diseases due to external agents	0.702	0.298
H20.9 Iridocyclitis, unspecified	0.701	0.299
S19 Other and unspecified injuries of neck	0.699	0.301
E20-E35 Disorders of other endocrine glands	0.698	0.302
S48 Traumatic amputation of shoulder and upper arm	0.697	0.303
S45 Injury of blood vessels at shoulder and upper arm level	0.697	0.303
S44 Injury of nerves at shoulder and upper arm level	0.697	0.303
S47 Crushing injury of shoulder and upper arm	0.697	0.303
H10-H13 Disorders of conjunctiva	0.696	0.303
S60-S69 Injuries to the wrist and hand	0.696	0.304
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.696	0.304
X10-X19 Contact with heat and hot substances	0.695	0.305
H36.8 Other retinal disorders in diseases classified elsewhere	0.694	0.305
F25 Schizoaffective disorders	0.694	0.306
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.692	0.308
E50-E64 Other nutritional deficiencies	0.690	0.310
L53.9 Erythematous condition, unspecified	0.689	0.311
L80 Vitiligo	0.688	0.312
I09 Other rheumatic heart diseases	0.687	0.313
I06 Rheumatic aortic valve diseases	0.687	0.313
I05 Rheumatic mitral valve diseases	0.687	0.313
O61 Failed induction of labour	0.687	0.313
J98 Other respiratory disorders	0.685	0.314
E14.8 With unspecified complications	0.685	0.315
E14.7 With multiple complications	0.685	0.315
E14.5 With peripheral circulatory complications	0.685	0.315
E14.4 With neurological complications	0.685	0.315
E14.2 Withrenal complications	0.685	0.315
E14.1 With ketoacidosis	0.685	0.315
E14.0 With coma	0.685	0.315
L10-L14 Bullous disorders	0.684	0.316
H55 Nystagmus and other irregular eye movements	0.684	0.316
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.684	0.316
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.683	0.317
O66 Other obstructed labour	0.683	0.317
F00-F09 Organic, including symptomatic, mental disorders	0.683	0.317
V80-V89 Other land transport accidents	0.682	0.318
Q21.1 Atrial septal defect	0.682	0.318
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.681	0.318
T51 Toxic effect of alcohol	0.681	0.319
H02.3 Blepharochalasis	0.681	0.319
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.681	0.319
H18 Other disorders of cornea	0.680	0.320
S11 Open wound of neck	0.680	0.320
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.680	0.320
E66.9 Obesity, unspecified	0.680	0.320
S42.0 Fracture of clavicle	0.678	0.322
F99-F99 Unspecified mental disorder	0.678	0.322
I08.9 Multiple valve disease, unspecified	0.676	0.324
Q80-Q89 Other congenital malformations	0.676	0.324
J86 Pyothorax	0.676	0.324
S42.9 Fracture of shoulder girdle, part unspecified	0.675	0.325
S42.8 Fracture of other parts of shoulder and upper arm	0.675	0.325
S42.7 Multiple fractures of clavicle, scapula and humerus	0.675	0.325
J00-J06 Acute upper respiratory infections	0.675	0.325
H35.3 Degeneration of macula and posterior pole	0.674	0.326
T93 Sequelae of injuries of lower limb	0.674	0.326
O23 Infections of genito-urinary tract in pregnancy	0.672	0.328
E11.0 With coma	0.672	0.328
F60-F69 Disorders of adult personality and behaviour	0.671	0.328
O64.1 Obstructed labour due to breech presentation	0.671	0.329
F31 Bipolar affective disorder	0.671	0.329
S59 Other and unspecified injuries of forearm	0.670	0.329
S58 Traumatic amputation of forearm	0.670	0.329
S57 Crushing injury of forearm	0.670	0.329
S56 Injury of muscle and tendon at forearm level	0.670	0.329
S55 Injury of blood vessels at forearm level	0.670	0.329
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.670	0.329
F22.0 Delusional disorder	0.670	0.330
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.670	0.330
S52.3 Fracture of shaft of radius	0.668	0.332
J98.1 Pulmonary collapse	0.667	0.333
S43.0 Dislocation of shoulder joint	0.667	0.333
A50-A64 Infections with a predominantly sexual mode of transmission	0.664	0.336
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.663	0.336
Q35-Q37 Cleft lip and cleft palate	0.663	0.336
Q30-Q34 Congenital malformations of the respiratory system	0.663	0.336
O62 Abnormalities of forces of labour	0.663	0.337
X20-X29 Contact with venomous animals and plants	0.662	0.338
Y35-Y36 Legal intervention and operations of war	0.661	0.339
Y10-Y34 Event of undetermined intent	0.661	0.339
Y00-Y09 Assault	0.661	0.339
X85-X99 Assault	0.661	0.339
X58-X59 Accidental exposure to other and unspecified factors	0.661	0.339
X30-X39 Exposure to forces of nature	0.661	0.339
X00-X09 Exposure to smoke, fire and flames	0.661	0.339
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.661	0.339
W75-W84 Other accidental threats to breathing	0.661	0.339
W65-W74 Accidental drowning and submersion	0.661	0.339
V98-V99 Other and unspecified transport accidents	0.661	0.339
V95-V97 Air and space transport accidents	0.661	0.339
V90-V94 Water transport accidents	0.661	0.339
V70-V79 Bus occupant injured in transport accident	0.661	0.339
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.661	0.339
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.661	0.339
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.661	0.339
V01-V09 Pedestrian injured in transport accident	0.661	0.339
S41.0 Open wound of shoulder	0.661	0.339
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.661	0.339
L94 Other localised connective tissue disorders	0.661	0.339
L87 Transepidermal elimination disorders	0.661	0.339
L88 Pyoderma gangrenosum	0.661	0.339
L86 Keratoderma in diseases classified elsewhere	0.661	0.339
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.660	0.340
G30 Alzheimer's disease	0.659	0.341
E40-E46 Malnutrition	0.659	0.341
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.658	0.341
L95 Vasculitis limited to skin, not elsewhere classified	0.657	0.343
L83 Acanthosis nigricans	0.657	0.343
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.655	0.345
I95-I99 Other and unspecified disorders of the circulatory system	0.655	0.345
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.655	0.345
H25 Senile cataract	0.653	0.347
F20 Schizophrenia	0.653	0.347
S49 Other and unspecified injuries of shoulder and upper arm	0.653	0.347
T00 Superficial injuries involving multiple body regions	0.651	0.349
E11.6 With other specified complications	0.650	0.349
L90.9 Atrophic disorder of skin, unspecified	0.650	0.350
L90.8 Other atrophic disorders of skin	0.650	0.350
L90.6 Striae atrophicae	0.650	0.350
L90.4 Acrodermatitis chronica atrophicans	0.650	0.350
L90.3 Atrophoderma of Pasini and Pierini	0.650	0.350
L90.2 Anetoderma of Jadassohn-Pellizzari	0.650	0.350
L90.1 Anetoderma of Schweninger-Buzzi	0.650	0.350
O00-O08 Pregnancy with abortive outcome	0.650	0.350
L81.9 Disorder of pigmentation, unspecified	0.650	0.350
E11.8 With unspecified complications	0.649	0.350
E11.7 With multiple complications	0.649	0.350
G61 Inflammatory polyneuropathy	0.649	0.351
Y40 Systemic antibiotics	0.648	0.352
O69 Labour and delivery complicated by umbilical cord complications	0.648	0.352
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.647	0.352
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.647	0.352
H17 Corneal scars and opacities	0.647	0.352
H15 Disorders of sclera	0.647	0.352
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.647	0.353
T36-T50 Poisoning by drugs, medicaments and biological substances	0.647	0.353
G62 Other polyneuropathies	0.647	0.353
Q23 Congenital malformations of aortic and mitral valves	0.647	0.353
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.646	0.354
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.644	0.356
F70-F79 Mental retardation	0.644	0.356
H47 Other disorders of optic [2nd] nerve and visual pathways	0.643	0.357
H35.1 Retinopathy of prematurity	0.642	0.358
B65-B83 Helminthiases	0.642	0.358
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.642	0.358
S92.0 Fracture of calcaneus	0.641	0.359
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.641	0.359
S26 Injury of heart	0.641	0.359
S25 Injury of blood vessels of thorax	0.641	0.359
S24 Injury of nerves and spinal cord at thorax level	0.641	0.359
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.641	0.359
S21 Open wound of thorax	0.641	0.359
O21 Excessive vomiting in pregnancy	0.641	0.359
Q12 Congenital lens malformations	0.640	0.360
S40 Superficial injury of shoulder and upper arm	0.638	0.361
T95 Sequelae of burns, corrosions and frostbite	0.638	0.362
H20.8 Other iridocyclitis	0.638	0.362
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.637	0.362
S10 Superficial injury of neck	0.638	0.362
S00-S09 Injuries to the head	0.636	0.364
Q24 Other congenital malformations of heart	0.636	0.364
X50 Overexertion and strenuous or repetitive movements	0.635	0.365
G23 Other degenerative diseases of basal ganglia	0.634	0.366
G21 Secondary Parkinsonism	0.634	0.366
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.634	0.366
G22 Parkinsonism in diseases classified elsewhere	0.634	0.366
S42.11 Fracture of scapula (open)	0.633	0.366
J90-J94 Other diseases of pleura	0.633	0.367
H02.7 Other degenerative disorders of eyelid and periocular area	0.633	0.367
H02.2 Lagophthalmos	0.633	0.367
H02.5 Other disorders affecting eyelid function	0.633	0.367
S54.0 Injury of ulnar nerve at forearm level	0.633	0.367
L92.0 Granuloma annulare	0.632	0.368
S70 Superficial injury of hip and thigh	0.632	0.368
E67 Other hyperalimentation	0.631	0.369
E68 Sequelae of hyperalimentation	0.631	0.369
A04 Other bacterial intestinal infections	0.630	0.370
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.629	0.371
G63.2 Diabetic polyneuropathy	0.629	0.371
Q60-Q64 Congenital malformations of the urinary system	0.629	0.371
J99 Respiratory disorders in diseases classified elsewhere	0.627	0.373
H25.9 Senile cataract, unspecified	0.627	0.373
Chapter II Neoplasms	0.627	0.373
S29.9 Unspecified injury of thorax	0.626	0.374
L54 Erythema in diseases classified elsewhere	0.625	0.374
L51 Erythema multiforme	0.625	0.374
L52 Erythema nodosum	0.625	0.374
S42.30 Fracture of shaft of humerus (closed)	0.624	0.376
S52.7 Multiple fractures of forearm	0.623	0.377
S91 Open wound of ankle and foot	0.623	0.377
L00-L08 Infections of the skin and subcutaneous tissue	0.623	0.377
F80-F89 Disorders of psychological development	0.622	0.378
V20-V29 Motorcycle rider injured in transport accident	0.622	0.378
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.622	0.378
A02 Other Salmonella infections	0.621	0.379
J40-J47 Chronic lower respiratory diseases	0.620	0.380
B90-B94 Sequelae of infectious and parasitic diseases	0.619	0.381
Q07 Other congenital malformations of nervous system	0.619	0.381
S12 Fracture of neck	0.619	0.381
J85 Abscess of lung and mediastinum	0.618	0.382
S52.9 Fracture of forearm, part unspecified	0.618	0.382
S52.4 Fracture of shafts of both ulna and radius	0.618	0.382
S52.2 Fracture of shaft of ulna	0.618	0.382
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.617	0.383
S52.1 Fracture of upper end of radius	0.616	0.384
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.616	0.384
S20 Superficial injury of thorax	0.616	0.384
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.615	0.385
O75.0 Maternal distress during labour and delivery	0.615	0.385
S17 Crushing injury of neck	0.614	0.386
S15 Injury of blood vessels at neck level	0.614	0.386
S14 Injury of nerves and spinal cord at neck level	0.614	0.386
S18 Traumatic amputation at neck level	0.614	0.386
S16 Injury of muscle and tendon at neck level	0.614	0.386
S50.8 Other superficial injuries of forearm	0.614	0.386
S71 Open wound of hip and thigh	0.613	0.387
O71 Other obstetric trauma	0.612	0.387
O29 Complications of anaesthesia during pregnancy	0.612	0.387
O28 Abnormal findings on antenatal screening of mother	0.612	0.387
O22 Venous complications in pregnancy	0.612	0.387
O25 Malnutrition in pregnancy	0.612	0.387
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.612	0.388
O97 Death from sequelae of direct obstetric causes	0.612	0.388
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.612	0.388
O95 Obstetric death of unspecified cause	0.612	0.388
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.612	0.388
B20-B24 Human immunodeficiency virus [HIV] disease	0.611	0.389
S52.50 Fracture of lower end of radius (closed)	0.611	0.389
S62 Fracture at wrist and hand level	0.610	0.390
G00-G09 Inflammatory diseases of the central nervous system	0.609	0.391
H34.9 Retinal vascular occlusion, unspecified	0.608	0.392
H34.1 Central retinal artery occlusion	0.608	0.392
H34.0 Transient retinal artery occlusion	0.608	0.392
I24 Other acute ischaemic heart diseases	0.608	0.392
I10-I15 Hypertensive diseases	0.608	0.392
F29 Unspecified nonorganic psychosis	0.607	0.393
H57 Other disorders of eye and adnexa	0.606	0.394
W13 Fall from, out of or through building or structure	0.606	0.394
E16.2 Hypoglycaemia, unspecified	0.606	0.394
H16 Keratitis	0.604	0.396
G70 Myasthenia gravis and other myoneural disorders	0.604	0.396
E15 Nondiabetic hypoglycaemic coma	0.603	0.397
X51 Travel and motion	0.603	0.397
L50.0 Allergic urticaria	0.603	0.397
S99 Other and unspecified injuries of ankle and foot	0.602	0.398
S98 Traumatic amputation of ankle and foot	0.602	0.398
S97 Crushing injury of ankle and foot	0.602	0.398
S96 Injury of muscle and tendon at ankle and foot level	0.602	0.398
S95 Injury of blood vessels at ankle and foot level	0.602	0.398
S94 Injury of nerves at ankle and foot level	0.602	0.398
O26.9 Pregnancy-related condition, unspecified	0.602	0.398
H21.8 Other specified disorders of iris and ciliary body	0.602	0.398
L21 Seborrhoeic dermatitis	0.602	0.398
Q05 Spina bifida	0.601	0.399
S42.21 Fracture of upper end of humerus (open)	0.601	0.399
S27.0 Traumatic pneumothorax	0.601	0.399
T68 Hypothermia	0.601	0.399
E11.2 With renal complications	0.600	0.400
L81.8 Other specified disorders of pigmentation	0.599	0.400
L81.7 Pigmented purpuric dermatosis	0.599	0.400
L81.6 Other disorders of diminished melanin formation	0.599	0.400
L81.5 Leukoderma, not elsewhere classified	0.599	0.400
L81.3 Cafe au lait spots	0.599	0.400
L81.2 Freckles	0.599	0.400
L81.1 Chloasma	0.599	0.400
L81.0 Postinflammatory hyperpigmentation	0.599	0.400
T23 Burn and corrosion of wrist and hand	0.599	0.401
I07 Rheumatic tricuspid valve diseases	0.599	0.401
O74 Complications of anaesthesia during labour and delivery	0.599	0.401
O65 Obstructed labour due to maternal pelvic abnormality	0.599	0.401
O60 Preterm delivery	0.599	0.401
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.597	0.403
I22 Subsequent myocardial infarction	0.597	0.403
F28 Other nonorganic psychotic disorders	0.596	0.404
F24 Induced delusional disorder	0.596	0.404
F21 Schizotypal disorder	0.596	0.404
B99-B99 Other infectious diseases	0.596	0.404
B85-B89 Pediculosis, acariasis and other infestations	0.596	0.404
B50-B64 Protozoal diseases	0.596	0.404
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.596	0.404
A75-A79 Rickettsioses	0.596	0.404
A70-A74 Other diseases caused by chlamydiae	0.596	0.404
A65-A69 Other spirochaetal diseases	0.596	0.404
A20-A28 Certain zoonotic bacterial diseases	0.596	0.404
A15-A19 Tuberculosis	0.596	0.404
T18 Foreign body in alimentary tract	0.596	0.404
H33 Retinal detachments and breaks	0.596	0.404
F25.9 Schizoaffective disorder, unspecified	0.595	0.405
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.595	0.405
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.595	0.405
T16 Foreign body in ear	0.595	0.405
S50.9 Superficial injury of forearm, unspecified	0.594	0.406
Y54.3 Benzothiadiazine derivatives	0.594	0.406
F31.9 Bipolar affective disorder, unspecified	0.594	0.406
O80-O84 Delivery	0.593	0.407
J86.9 Pyothorax without fistula	0.592	0.408
E16.1 Other hypoglycaemia	0.592	0.408
Chapter VIII Diseases of the ear and mastoid process	0.592	0.408
S92.00 Fracture of calcaneus (closed)	0.591	0.409
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.591	0.409
H02.1 Ectropion of eyelid	0.591	0.409
I20 Angina pectoris	0.591	0.409
J30-J39 Other diseases of upper respiratory tract	0.590	0.410
Q26 Congenital malformations of great veins	0.590	0.410
Q25 Congenital malformations of great arteries	0.590	0.410
Q22 Congenital malformations of pulmonary and tricuspid valves	0.590	0.410
Q20 Congenital malformations of cardiac chambers and connexions	0.590	0.410
T63 Toxic effect of contact with venomous animals	0.590	0.410
G31.8 Other specified degenerative diseases of nervous system	0.589	0.411
S22.2 Fracture of sternum	0.589	0.411
L90.0 Lichen sclerosus et atrophicus	0.589	0.411
T51.9 Alcohol, unspecified	0.589	0.411
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.589	0.411
L50.9 Urticaria, unspecified	0.588	0.412
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.587	0.412
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.587	0.413
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.587	0.413
O26.5 Maternal hypotension syndrome	0.587	0.413
O26.4 Herpes gestationis	0.587	0.413
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.587	0.413
O26.2 Pregnancy care of habitual aborter	0.587	0.413
O26.1 Low weight gain in pregnancy	0.587	0.413
O26.0 Excessive weight gain in pregnancy	0.587	0.413
A80-A89 Viral infections of the central nervous system	0.587	0.413
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.586	0.413
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.586	0.414
F39 Unspecified mood [affective] disorder	0.586	0.414
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.585	0.415

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations