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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4261353
log Bayes Factor = 0.16368
Chromosome 3   position 191,695,113  (GRCh37) Explore rs4261353 on Ensembl!
Variant rs4261353 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.313 0.687 0.000
Chapter V Mental and behavioural disorders
0.312 0.688 0.000
Chapter VI Diseases of the nervous system
0.300 0.700 0.000
F30-F39 Mood [affective] disorders
0.298 0.702 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.296 0.704 0.000
Chapter IX Diseases of the circulatory system
0.295 0.705 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.291 0.709 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.290 0.710 0.000
F32 Depressive episode
0.288 0.712 0.000
I30-I52 Other forms of heart disease
0.286 0.714 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.282 0.718 0.000
G40-G47 Episodic and paroxysmal disorders
0.282 0.718 0.000
F32.9 Depressive episode, unspecified
0.282 0.718 0.000
M20-M25 Other joint disorders
0.278 0.722 0.000
Chapter I Certain infectious and parasitic diseases
0.276 0.724 0.000
E70-E90 Metabolic disorders
0.274 0.726 0.000
F41 Other anxiety disorders
0.274 0.726 0.000
I50 Heart failure
0.266 0.734 0.000
M23 Internal derangement of knee
0.263 0.737 0.000
G40 Epilepsy
0.256 0.744 0.000
Chapter II Neoplasms
0.254 0.746 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.253 0.747 0.000
S00-S09 Injuries to the head
0.250 0.750 0.000
M50-M54 Other dorsopathies
0.248 0.752 0.000
I35 Nonrheumatic aortic valve disorders
0.248 0.752 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.248 0.752 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.243 0.757 0.000
F41.9 Anxiety disorder, unspecified
0.240 0.760 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.240 0.760 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.240 0.760 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.238 0.762 0.000
I50.1 Left ventricular failure
0.235 0.765 0.000
G43 Migraine
0.235 0.765 0.000
I60-I69 Cerebrovascular diseases
0.234 0.766 0.000
E65-E68 Obesity and other hyperalimentation
0.233 0.767 0.000
E86 Volume depletion
0.232 0.768 0.000
G47 Sleep disorders
0.231 0.769 0.000
G30-G32 Other degenerative diseases of the nervous system
0.231 0.769 0.000
F41.2 Mixed anxiety and depressive disorder
0.231 0.769 0.000
G40.9 Epilepsy, unspecified
0.230 0.770 0.000
M65-M68 Disorders of synovium and tendon
0.230 0.770 0.000
Chapter XX External causes of morbidity and mortality
0.229 0.771 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.228 0.772 0.000
Chapter VIII Diseases of the ear and mastoid process
0.228 0.772 0.000
A30-A49 Other bacterial diseases
0.228 0.772 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.226 0.774 0.000
G20-G26 Extrapyramidal and movement disorders
0.226 0.774 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.225 0.774 0.000
I50.0 Congestive heart failure
0.225 0.775 0.000
Chapter XXII Codes for special purposes
0.224 0.776 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.224 0.776 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.224 0.776 0.000
I51 Complications and ill-defined descriptions of heart disease
0.224 0.776 0.000
Chapter VII Diseases of the eye and adnexa
0.224 0.776 0.000
F99-F99 Unspecified mental disorder
0.224 0.776 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.224 0.776 0.000
F80-F89 Disorders of psychological development
0.224 0.776 0.000
F70-F79 Mental retardation
0.224 0.776 0.000
F60-F69 Disorders of adult personality and behaviour
0.224 0.776 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.224 0.776 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.224 0.776 0.000
M45-M49 Spondylopathies
0.224 0.776 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.221 0.779 0.000
M23.3 Other meniscus derangements
0.221 0.779 0.000
M25 Other joint disorders, not elsewhere classified
0.221 0.779 0.000
I05-I09 Chronic rheumatic heart diseases
0.220 0.780 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.219 0.780 0.000
A00-A09 Intestinal infectious diseases
0.219 0.781 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.219 0.781 0.000
I45 Other conduction disorders
0.218 0.782 0.000
E50-E64 Other nutritional deficiencies
0.217 0.783 0.000
S01 Open wound of head
0.217 0.783 0.000
D10-D36 Benign neoplasms
0.216 0.784 0.000
S40-S49 Injuries to the shoulder and upper arm
0.216 0.784 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.216 0.784 0.000
G90-G99 Other disorders of the nervous system
0.215 0.785 0.000
G70-G73 Diseases of myoneural junction and muscle
0.215 0.785 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.215 0.785 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.215 0.785 0.000
I10-I15 Hypertensive diseases
0.215 0.785 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.214 0.786 0.000
F38 Other mood [affective] disorders
0.214 0.786 0.000
F34 Persistent mood [affective] disorders
0.214 0.786 0.000
F33 Recurrent depressive disorder
0.214 0.786 0.000
F31 Bipolar affective disorder
0.214 0.786 0.000
F30 Manic episode
0.214 0.786 0.000
F39 Unspecified mood [affective] disorder
0.214 0.786 0.000
D50-D53 Nutritional anaemias
0.213 0.787 0.000
I31 Other diseases of pericardium
0.213 0.787 0.000
M70-M79 Other soft tissue disorders
0.213 0.787 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.213 0.787 0.000
S60-S69 Injuries to the wrist and hand
0.212 0.788 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.212 0.788 0.000
M91-M94 Chondropathies
0.212 0.788 0.000
M86-M90 Other osteopathies
0.212 0.788 0.000
M60-M63 Disorders of muscles
0.212 0.788 0.000
M40-M43 Deforming dorsopathies
0.212 0.788 0.000
M00-M03 Infectious arthropathies
0.212 0.788 0.000
I00-I02 Acute rheumatic fever
0.212 0.788 0.000
I47 Paroxysmal tachycardia
0.211 0.789 0.000
B35-B49 Mycoses
0.210 0.790 0.000
G35 Multiple sclerosis
0.210 0.790 0.000
E40-E46 Malnutrition
0.209 0.791 0.000
E20-E35 Disorders of other endocrine glands
0.209 0.791 0.000
B95-B98 Bacterial, viral and other infectious agents
0.209 0.791 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.208 0.792 0.000
F48 Other neurotic disorders
0.208 0.792 0.000
F45 Somatoform disorders
0.208 0.792 0.000
F44 Dissociative [conversion] disorders
0.208 0.792 0.000
F43 Reaction to severe stress, and adjustment disorders
0.208 0.792 0.000
F42 Obsessive-compulsive disorder
0.208 0.792 0.000
F40 Phobic anxiety disorders
0.208 0.792 0.000
I49 Other cardiac arrhythmias
0.208 0.792 0.000
S50-S59 Injuries to the elbow and forearm
0.207 0.792 0.000
F32.8 Other depressive episodes
0.207 0.793 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.207 0.793 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.207 0.793 0.000
F32.1 Moderate depressive episode
0.207 0.793 0.000
F32.0 Mild depressive episode
0.207 0.793 0.000
I35.0 Aortic (valve) stenosis
0.206 0.794 0.000
M54 Dorsalgia
0.206 0.794 0.000
I52 Other heart disorders in diseases classified elsewhere
0.205 0.794 0.000
I48 Atrial fibrillation and flutter
0.205 0.794 0.000
I46 Cardiac arrest
0.205 0.794 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.205 0.794 0.000
I42 Cardiomyopathy
0.205 0.794 0.000
I41 Myocarditis in diseases classified elsewhere
0.205 0.794 0.000
I40 Acute myocarditis
0.205 0.794 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.205 0.794 0.000
I37 Pulmonary valve disorders
0.205 0.794 0.000
I36 Nonrheumatic tricuspid valve disorders
0.205 0.794 0.000
I33 Acute and subacute endocarditis
0.205 0.794 0.000
I32 Pericarditis in diseases classified elsewhere
0.205 0.794 0.000
I30 Acute pericarditis
0.205 0.794 0.000
I38 Endocarditis, valve unspecified
0.205 0.794 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.205 0.795 0.000
M80-M85 Disorders of bone density and structure
0.203 0.797 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.203 0.797 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.202 0.797 0.000
T79-T79 Certain early complications of trauma
0.202 0.797 0.000
T66-T78 Other and unspecified effects of external causes
0.202 0.797 0.000
T33-T35 Frostbite
0.202 0.797 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.202 0.797 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.202 0.797 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.202 0.797 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.202 0.797 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.202 0.797 0.000
T00-T07 Injuries involving multiple body regions
0.202 0.797 0.000
S90-S99 Injuries to the ankle and foot
0.202 0.797 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.202 0.797 0.000
S20-S29 Injuries to the thorax
0.202 0.797 0.000
S10-S19 Injuries to the neck
0.202 0.797 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.202 0.797 0.000
G44 Other headache syndromes
0.202 0.797 0.000
G41 Status epilepticus
0.202 0.797 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.202 0.798 0.000
I44 Atrioventricular and left bundle-branch block
0.202 0.798 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.202 0.798 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.202 0.798 0.000
I50.9 Heart failure, unspecified
0.201 0.799 0.000
G43.9 Migraine, unspecified
0.201 0.799 0.000
I83 Varicose veins of lower extremities
0.200 0.800 0.000
S00 Superficial injury of head
0.200 0.800 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.199 0.801 0.000
M35 Other systemic involvement of connective tissue
0.199 0.801 0.000
M34 Systemic sclerosis
0.199 0.801 0.000
M33 Dermatopolymyositis
0.199 0.801 0.000
M32 Systemic lupus erythematosus
0.199 0.801 0.000
M31 Other necrotising vasculopathies
0.199 0.801 0.000
M30 Polyarteritis nodosa and related conditions
0.199 0.801 0.000
M24 Other specific joint derangements
0.199 0.801 0.000
M22 Disorders of patella
0.199 0.801 0.000
M21 Other acquired deformities of limbs
0.199 0.801 0.000
E83 Disorders of mineral metabolism
0.199 0.801 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.199 0.801 0.000
S70-S79 Injuries to the hip and thigh
0.198 0.802 0.000
S80-S89 Injuries to the knee and lower leg
0.198 0.802 0.000
B99-B99 Other infectious diseases
0.198 0.802 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.198 0.802 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.198 0.802 0.000
B65-B83 Helminthiases
0.198 0.802 0.000
B50-B64 Protozoal diseases
0.198 0.802 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.198 0.802 0.000
B15-B19 Viral hepatitis
0.198 0.802 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.198 0.802 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.198 0.802 0.000
A80-A89 Viral infections of the central nervous system
0.198 0.802 0.000
A75-A79 Rickettsioses
0.198 0.802 0.000
A70-A74 Other diseases caused by chlamydiae
0.198 0.802 0.000
A65-A69 Other spirochaetal diseases
0.198 0.802 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.198 0.802 0.000
A20-A28 Certain zoonotic bacterial diseases
0.198 0.802 0.000
A15-A19 Tuberculosis
0.198 0.802 0.000
E88 Other metabolic disorders
0.197 0.803 0.000
E85 Amyloidosis
0.197 0.803 0.000
E84 Cystic fibrosis
0.197 0.803 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.197 0.803 0.000
E79 Disorders of purine and pyrimidine metabolism
0.197 0.803 0.000
E77 Disorders of glycoprotein metabolism
0.197 0.803 0.000
E76 Disorders of glycosaminoglycan metabolism
0.197 0.803 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.197 0.803 0.000
E74 Other disorders of carbohydrate metabolism
0.197 0.803 0.000
E73 Lactose intolerance
0.197 0.803 0.000
E72 Other disorders of amino-acid metabolism
0.197 0.803 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.197 0.803 0.000
E70 Disorders of aromatic amino-acid metabolism
0.197 0.803 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.197 0.803 0.000
F41.8 Other specified anxiety disorders
0.197 0.803 0.000
F41.3 Other mixed anxiety disorders
0.197 0.803 0.000
F41.1 Generalised anxiety disorder
0.197 0.803 0.000
B25-B34 Other viral diseases
0.195 0.805 0.000
E87.6 Hypokalaemia
0.194 0.806 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.194 0.806 0.000
M05-M14 Inflammatory polyarthropathies
0.194 0.806 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.194 0.806 0.000
C15-C26 Malignant neoplasms of digestive organs
0.194 0.806 0.000
A41 Other septicaemia
0.193 0.807 0.000
E66 Obesity
0.191 0.809 0.000
M51 Other intervertebral disk disorders
0.191 0.809 0.000
C51-C58 Malignant neoplasms of female genital organs
0.190 0.810 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.188 0.811 0.000
M23.9 Internal derangement of knee, unspecified
0.188 0.812 0.000
M23.8 Other internal derangements of knee
0.188 0.812 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.188 0.812 0.000
M23.5 Chronic instability of knee
0.188 0.812 0.000
M23.4 Loose body in knee
0.188 0.812 0.000
M23.1 Discoid meniscus (congenital)
0.188 0.812 0.000
M23.0 Cystic meniscus
0.188 0.812 0.000
F03 Unspecified dementia
0.188 0.812 0.000
G47.3 Sleep apnoea
0.188 0.812 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.188 0.812 0.000
M20 Acquired deformities of fingers and toes
0.188 0.812 0.000
M15-M19 Arthrosis
0.187 0.813 0.000
E10-E14 Diabetes mellitus
0.186 0.814 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.186 0.814 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.185 0.814 0.000
E87.5 Hyperkalaemia
0.185 0.815 0.000
G40.8 Other epilepsy
0.184 0.816 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.184 0.816 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.184 0.816 0.000
G40.5 Special epileptic syndromes
0.184 0.816 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.184 0.816 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.184 0.816 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.184 0.816 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.184 0.816 0.000
C64-C68 Malignant neoplasms of urinary tract
0.183 0.817 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.183 0.817 0.000
M65 Synovitis and tenosynovitis
0.182 0.817 0.000
I67 Other cerebrovascular diseases
0.182 0.818 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.182 0.818 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.182 0.818 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.182 0.818 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.182 0.818 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.182 0.818 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.182 0.818 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.182 0.818 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.182 0.818 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.182 0.818 0.000
D18 Haemangioma and lymphangioma, any site
0.181 0.818 0.000
E78.0 Pure hypercholesterolaemia
0.181 0.819 0.000
D80-D89 Certain disorders involving the immune mechanism
0.181 0.819 0.000
D55-D59 Haemolytic anaemias
0.181 0.819 0.000
I80 Phlebitis and thrombophlebitis
0.181 0.819 0.000
D00-D09 In situ neoplasms
0.181 0.819 0.000
S01.0 Open wound of scalp
0.181 0.819 0.000
I20-I25 Ischaemic heart diseases
0.181 0.819 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.180 0.819 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.180 0.819 0.000
S09 Other and unspecified injuries of head
0.179 0.821 0.000
S08 Traumatic amputation of part of head
0.179 0.821 0.000
S07 Crushing injury of head
0.179 0.821 0.000
S06 Intracranial injury
0.179 0.821 0.000
S05 Injury of eye and orbit
0.179 0.821 0.000
S04 Injury of cranial nerves
0.179 0.821 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.179 0.821 0.000
S02 Fracture of skull and facial bones
0.179 0.821 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.179 0.821 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.179 0.821 0.000
E00-E07 Disorders of thyroid gland
0.178 0.821 0.000
D60-D64 Aplastic and other anaemias
0.178 0.822 0.000
M53 Other dorsopathies, not elsewhere classified
0.178 0.822 0.000
M50 Cervical disk disorders
0.178 0.822 0.000
M47 Spondylosis
0.178 0.822 0.000
I35.9 Aortic valve disorder, unspecified
0.178 0.822 0.000
I35.8 Other aortic valve disorders
0.178 0.822 0.000
I35.1 Aortic (valve) insufficiency
0.178 0.822 0.000
D25 Leiomyoma of uterus
0.178 0.822 0.000
I63 Cerebral infarction
0.178 0.822 0.000
G37 Other demyelinating diseases of central nervous system
0.178 0.822 0.000
G36 Other acute disseminated demyelination
0.178 0.822 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.177 0.822 0.000
I34 Nonrheumatic mitral valve disorders
0.177 0.822 0.000
H65-H75 Diseases of middle ear and mastoid
0.177 0.823 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.177 0.823 0.000
H43-H45 Disorders of vitreous body and globe
0.177 0.823 0.000
C60-C63 Malignant neoplasms of male genital organs
0.177 0.823 0.000
S01.8 Open wound of other parts of head
0.177 0.823 0.000
G47.9 Sleep disorder, unspecified
0.176 0.824 0.000
D50 Iron deficiency anaemia
0.176 0.824 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.175 0.825 0.000
D22 Melanocytic naevi
0.175 0.825 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.175 0.825 0.000
E87.2 Acidosis
0.174 0.825 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.174 0.826 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.174 0.826 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.174 0.826 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.174 0.826 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.174 0.826 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.174 0.826 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.174 0.826 0.000
S60 Superficial injury of wrist and hand
0.173 0.826 0.000
I51.8 Other ill-defined heart diseases
0.173 0.826 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.173 0.827 0.000
G20 Parkinson's disease
0.172 0.827 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.172 0.827 0.000
E87.7 Fluid overload
0.172 0.827 0.000
E87.4 Mixed disorder of acid-base balance
0.172 0.827 0.000
E87.3 Alkalosis
0.172 0.827 0.000
E87.0 Hyperosmolality and hypernatraemia
0.172 0.827 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.172 0.828 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.172 0.828 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.172 0.828 0.000
F02 Dementia in other diseases classified elsewhere
0.172 0.828 0.000
F01 Vascular dementia
0.172 0.828 0.000
F00 Dementia in Alzheimer's disease
0.172 0.828 0.000
F09 Unspecified organic or symptomatic mental disorder
0.172 0.828 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.172 0.828 0.000
G81 Hemiplegia
0.172 0.828 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.171 0.829 0.000
E16 Other disorders of pancreatic internal secretion
0.171 0.829 0.000
M25.5 Pain in joint
0.171 0.829 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.171 0.829 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.171 0.829 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.171 0.829 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.171 0.829 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.171 0.829 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.171 0.829 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.171 0.829 0.000
F11 Mental and behavioural disorders due to use of opioids
0.171 0.829 0.000
I10 Essential (primary) hypertension
0.171 0.829 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.170 0.829 0.000
D23 Other benign neoplasms of skin
0.170 0.830 0.000
A08 Viral and other specified intestinal infections
0.170 0.830 0.000
I69 Sequelae of cerebrovascular disease
0.170 0.830 0.000
M25.4 Effusion of joint
0.170 0.830 0.000
E66.8 Other obesity
0.170 0.830 0.000
I45.1 Other and unspecified right bundle-branch block
0.169 0.831 0.000
I51.7 Cardiomegaly
0.169 0.831 0.000
G43.8 Other migraine
0.168 0.831 0.000
G43.3 Complicated migraine
0.168 0.831 0.000
G43.2 Status migrainosus
0.168 0.831 0.000
G43.1 Migraine with aura [classical migraine]
0.168 0.831 0.000
G43.0 Migraine without aura [common migraine]
0.168 0.831 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.168 0.831 0.000
D51 Vitamin B12 deficiency anaemia
0.168 0.832 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.168 0.832 0.000
S42 Fracture of shoulder and upper arm
0.168 0.832 0.000
T51 Toxic effect of alcohol
0.168 0.832 0.000
H53-H54 Visual disturbances and blindness
0.168 0.832 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.168 0.832 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.168 0.832 0.000
I62 Other nontraumatic intracranial haemorrhage
0.168 0.832 0.000
I61 Intracerebral haemorrhage
0.168 0.832 0.000
I60 Subarachnoid haemorrhage
0.168 0.832 0.000
I47.2 Ventricular tachycardia
0.167 0.833 0.000
E67 Other hyperalimentation
0.167 0.833 0.000
E68 Sequelae of hyperalimentation
0.167 0.833 0.000
E65 Localised adiposity
0.167 0.833 0.000
M54.5 Low back pain
0.167 0.833 0.000
G47.8 Other sleep disorders
0.166 0.834 0.000
G47.4 Narcolepsy and cataplexy
0.166 0.834 0.000
G47.2 Disorders of the sleep-wake schedule
0.166 0.834 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.166 0.834 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.166 0.834 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.166 0.834 0.000
G30 Alzheimer's disease
0.166 0.834 0.000
I08 Multiple valve diseases
0.166 0.834 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.165 0.835 0.000
M67 Other disorders of synovium and tendon
0.165 0.835 0.000
M66 Spontaneous rupture of synovium and tendon
0.165 0.835 0.000
S00.8 Superficial injury of other parts of head
0.165 0.835 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.164 0.835 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.164 0.835 0.000
Y35-Y36 Legal intervention and operations of war
0.164 0.835 0.000
Y10-Y34 Event of undetermined intent
0.164 0.835 0.000
Y00-Y09 Assault
0.164 0.835 0.000
X85-X99 Assault
0.164 0.835 0.000
X60-X84 Intentional self-harm
0.164 0.835 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.164 0.835 0.000
X50-X57 Overexertion, travel and privation
0.164 0.835 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.164 0.835 0.000
X30-X39 Exposure to forces of nature
0.164 0.835 0.000
X20-X29 Contact with venomous animals and plants
0.164 0.835 0.000
X10-X19 Contact with heat and hot substances
0.164 0.835 0.000
X00-X09 Exposure to smoke, fire and flames
0.164 0.835 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.164 0.835 0.000
W75-W84 Other accidental threats to breathing
0.164 0.835 0.000
W65-W74 Accidental drowning and submersion
0.164 0.835 0.000
W50-W64 Exposure to animate mechanical forces
0.164 0.835 0.000
W20-W49 Exposure to inanimate mechanical forces
0.164 0.835 0.000
V98-V99 Other and unspecified transport accidents
0.164 0.835 0.000
V95-V97 Air and space transport accidents
0.164 0.835 0.000
V90-V94 Water transport accidents
0.164 0.835 0.000
V80-V89 Other land transport accidents
0.164 0.835 0.000
V70-V79 Bus occupant injured in transport accident
0.164 0.835 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.164 0.835 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.164 0.835 0.000
V40-V49 Car occupant injured in transport accident
0.164 0.835 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.164 0.835 0.000
V20-V29 Motorcycle rider injured in transport accident
0.164 0.835 0.000
V10-V19 Pedal cyclist injured in transport accident
0.164 0.835 0.000
V01-V09 Pedestrian injured in transport accident
0.164 0.835 0.000
E53 Deficiency of other B group vitamins
0.164 0.836 0.000
A41.9 Septicaemia, unspecified
0.164 0.836 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.164 0.836 0.000
I88 Nonspecific lymphadenitis
0.164 0.836 0.000
I87 Other disorders of veins
0.164 0.836 0.000
I86 Varicose veins of other sites
0.164 0.836 0.000
I85 Oesophageal varices
0.164 0.836 0.000
I82 Other venous embolism and thrombosis
0.164 0.836 0.000
I81 Portal vein thrombosis
0.164 0.836 0.000
H80-H83 Diseases of inner ear
0.164 0.836 0.000
H60-H62 Diseases of external ear
0.164 0.836 0.000
B37 Candidiasis
0.163 0.836 0.000
A49 Bacterial infection of unspecified site
0.163 0.836 0.000
A48 Other bacterial diseases, not elsewhere classified
0.163 0.836 0.000
A44 Bartonellosis
0.163 0.836 0.000
A43 Nocardiosis
0.163 0.836 0.000
A42 Actinomycosis
0.163 0.836 0.000
A40 Streptococcal septicaemia
0.163 0.836 0.000
A39 Meningococcal infection
0.163 0.836 0.000
A37 Whooping cough
0.163 0.836 0.000
A36 Diphtheria
0.163 0.836 0.000
A32 Listeriosis
0.163 0.836 0.000
A31 Infection due to other mycobacteria
0.163 0.836 0.000
A30 Leprosy [Hansen's disease]
0.163 0.836 0.000
A46 Erysipelas
0.163 0.836 0.000
A38 Scarlet fever
0.163 0.836 0.000
A35 Other tetanus
0.163 0.836 0.000
A34 Obstetrical tetanus
0.163 0.836 0.000
A33 Tetanus neonatorum
0.163 0.836 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.163 0.836 0.000
G25 Other extrapyramidal and movement disorders
0.162 0.838 0.000
G24 Dystonia
0.162 0.838 0.000
G23 Other degenerative diseases of basal ganglia
0.162 0.838 0.000
G21 Secondary Parkinsonism
0.162 0.838 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.162 0.838 0.000
G22 Parkinsonism in diseases classified elsewhere
0.162 0.838 0.000
G62 Other polyneuropathies
0.162 0.838 0.000
G83 Other paralytic syndromes
0.162 0.838 0.000
G82 Paraplegia and tetraplegia
0.162 0.838 0.000
G80 Infantile cerebral palsy
0.162 0.838 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.162 0.838 0.000
P90-P96 Other disorders originating in the perinatal period
0.161 0.839 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.161 0.839 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.161 0.839 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.161 0.839 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.161 0.839 0.000
P35-P39 Infections specific to the perinatal period
0.161 0.839 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.161 0.839 0.000
P10-P15 Birth trauma
0.161 0.839 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.161 0.839 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.161 0.839 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.161 0.839 0.000
Q80-Q89 Other congenital malformations
0.161 0.839 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.161 0.839 0.000
Q60-Q64 Congenital malformations of the urinary system
0.161 0.839 0.000
Q50-Q56 Congenital malformations of genital organs
0.161 0.839 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.161 0.839 0.000
Q35-Q37 Cleft lip and cleft palate
0.161 0.839 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.161 0.839 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.161 0.839 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.161 0.839 0.000
Q00-Q07 Congenital malformations of the nervous system
0.161 0.839 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.161 0.839 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.161 0.839 0.000
I77 Other disorders of arteries and arterioles
0.161 0.839 0.000
I51.9 Heart disease, unspecified
0.161 0.839 0.000
I51.6 Cardiovascular disease, unspecified
0.161 0.839 0.000
I51.5 Myocardial degeneration
0.161 0.839 0.000
I51.4 Myocarditis, unspecified
0.161 0.839 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.161 0.839 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.161 0.839 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.161 0.839 0.000
I51.0 Cardiac septal defect, acquired
0.161 0.839 0.000
H55-H59 Other disorders of eye and adnexa
0.161 0.839 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.161 0.839 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.161 0.839 0.000
H10-H13 Disorders of conjunctiva
0.161 0.839 0.000
F25 Schizoaffective disorders
0.161 0.839 0.000
F23 Acute and transient psychotic disorders
0.161 0.839 0.000
F22 Persistent delusional disorders
0.161 0.839 0.000
F20 Schizophrenia
0.161 0.839 0.000
F29 Unspecified nonorganic psychosis
0.161 0.839 0.000
F28 Other nonorganic psychotic disorders
0.161 0.839 0.000
F24 Induced delusional disorder
0.161 0.839 0.000
F21 Schizotypal disorder
0.161 0.839 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.161 0.839 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.161 0.839 0.000
F51 Nonorganic sleep disorders
0.161 0.839 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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