TreeWAS – Variant ID: rs4470583

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
# Top node	0.000	1.000
Chapter XXI Factors influencing health status and contact with health services	0.000	1.000
Chapter XI Diseases of the digestive system	0.000	1.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.001	0.999
Z40-Z54 Persons encountering health services for specific procedures and health care	0.004	0.996
K55-K64 Other diseases of intestines	0.005	0.995
Chapter II Neoplasms	0.013	0.987
K20-K31 Diseases of oesophagus, stomach and duodenum	0.018	0.982
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.022	0.978
Chapter XIV Diseases of the genitourinary system	0.030	0.970
Z53 Persons encountering health services for specifie procedures, not carried out	0.032	0.968
Z51 Other medical care	0.036	0.964
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.052	0.948
Chapter IX Diseases of the circulatory system	0.063	0.937
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.074	0.926
Z87 Personal history of other diseases and conditions	0.079	0.921
K62 Other diseases of anus and rectum	0.079	0.921
K59 Other functional intestinal disorders	0.080	0.920
K22 Other diseases of oesophagus	0.099	0.901
Chapter I Certain infectious and parasitic diseases	0.101	0.899
Z53.8 Procedure not carried out for other reasons	0.109	0.891
N30-N39 Other diseases of urinary system	0.110	0.890
Chapter IV Endocrine, nutritional and metabolic diseases	0.111	0.889
Z96 Presence of other functional implants	0.115	0.885
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.115	0.885
Chapter VIII Diseases of the ear and mastoid process	0.119	0.881
M70-M79 Other soft tissue disorders	0.124	0.876
Chapter X Diseases of the respiratory system	0.125	0.875
N80-N98 Noninflammatory disorders of female genital tract	0.127	0.873
Z51.1 Chemotherapy session for neoplasm	0.130	0.870
K29 Gastritis and duodenitis	0.131	0.869
M15-M19 Arthrosis	0.134	0.866
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.136	0.864
Z91 Personal history of risk-factors, not elsewhere classified	0.140	0.860
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.140	0.860
K57 Diverticular disease of intestine	0.140	0.860
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.141	0.859
K59.0 Constipation	0.142	0.858
Chapter XX External causes of morbidity and mortality	0.147	0.853
K20 Oesophagitis	0.151	0.849
Z53.0 Procedure not carried out because of contraindication	0.152	0.848
K63 Other diseases of intestine	0.153	0.847
Z80 Family history of malignant neoplasm	0.154	0.846
Z98 Other postsurgical states	0.154	0.846
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.157	0.843
Z85 Personal history of malignant neoplasm	0.162	0.838
Z51.8 Other specified medical care	0.163	0.837
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.163	0.837
M20-M25 Other joint disorders	0.164	0.836
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.168	0.832
K56 Paralytic ileus and intestinal obstruction without hernia	0.168	0.831
C15-C26 Malignant neoplasms of digestive organs	0.178	0.822
E70-E90 Metabolic disorders	0.182	0.818
K22.1 Ulcer of oesophagus	0.182	0.818
I20-I25 Ischaemic heart diseases	0.188	0.812
Z92 Personal history of medical treatment	0.190	0.810
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.192	0.808
K62.1 Rectal polyp	0.194	0.806
Z87.4 Personal history of diseases of the genito-urinary system	0.196	0.804
K26 Duodenal ulcer	0.196	0.804
Z87.1 Personal history of diseases of the digestive system	0.200	0.800
D10-D36 Benign neoplasms	0.200	0.800
K21 Gastro-oesophageal reflux disease	0.205	0.795
Z94 Transplanted organ and tissue status	0.207	0.793
K90-K93 Other diseases of the digestive system	0.207	0.793
R30-R39 Symptoms and signs involving the urinary system	0.209	0.791
K50-K52 Noninfective enteritis and colitis	0.214	0.786
C79 Secondary malignant neoplasm of other sites	0.216	0.784
Z00-Z13 Persons encountering health services for examination and investigation	0.217	0.783
C64-C68 Malignant neoplasms of urinary tract	0.218	0.782
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.221	0.779
Z53.9 Procedure not carried out, unspecified reason	0.221	0.778
Z51.5 Palliative care	0.222	0.778
Z48 Other surgical follow-up care	0.226	0.774
Chapter XXII Codes for special purposes	0.228	0.772
C50-C50 Malignant neoplasm of breast	0.232	0.768
N17-N19 Renal failure	0.236	0.764
K62.8 Other specified diseases of anus and rectum	0.238	0.761
Z88.1 Personal history of allergy to other antibiotic agents	0.239	0.761
Z90 Acquired absence of organs, not elsewhere classified	0.239	0.761
N60-N64 Disorders of breast	0.239	0.761
K63.5 Polyp of colon	0.241	0.758
Chapter VII Diseases of the eye and adnexa	0.244	0.756
Z70-Z76 Persons encountering health services in other circumstances	0.244	0.756
Z96.6 Presence of orthopaedic joint implants	0.245	0.755
B95-B98 Bacterial, viral and other infectious agents	0.245	0.755
R10 Abdominal and pelvic pain	0.245	0.755
D00-D09 In situ neoplasms	0.247	0.753
Z51.0 Radiotherapy session	0.249	0.751
N10-N16 Renal tubulo-interstitial diseases	0.249	0.751
N32 Other disorders of bladder	0.250	0.750
K29.6 Other gastritis	0.250	0.750
A00-A09 Intestinal infectious diseases	0.256	0.744
D37-D48 Neoplasms of uncertain or unknown behaviour	0.256	0.743
Z52 Donors of organs and tissues	0.257	0.743
Z51.3 Blood transfusion without reported diagnosis	0.258	0.742
H90-H95 Other disorders of ear	0.259	0.741
M79 Other soft tissue disorders, not elsewhere classified	0.260	0.740
Z49 Care involving dialysis	0.260	0.740
Chapter XV Pregnancy, childbirth and the puerperium	0.260	0.740
Z83 Family history of other specific disorders	0.261	0.739
M40-M43 Deforming dorsopathies	0.262	0.738
Z89 Acquired absence of limb	0.262	0.738
R11 Nausea and vomiting	0.264	0.736
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.265	0.735
K58 Irritable bowel syndrome	0.265	0.734
K22.2 Oesophageal obstruction	0.266	0.734
K70-K77 Diseases of liver	0.267	0.733
Z84 Family history of other conditions	0.268	0.732
N30 Cystitis	0.268	0.732
Z44 Fitting and adjustment of external prosthetic device	0.269	0.731
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.271	0.729
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.272	0.728
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.273	0.727
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.274	0.726
I70-I79 Diseases of arteries, arterioles and capillaries	0.274	0.726
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.274	0.726
N86 Erosion and ectropion of cervix uteri	0.275	0.725
D60-D64 Aplastic and other anaemias	0.275	0.725
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.277	0.723
Z50 Care involving use of rehabilitation procedures	0.277	0.723
N99-N99 Other disorders of the genitourinary system	0.277	0.723
M65-M68 Disorders of synovium and tendon	0.277	0.722
Z96.1 Presence of intraocular lens	0.278	0.722
Z80.0 Family history of malignant neoplasm of digestive organs	0.278	0.722
Z45 Adjustment and management of implanted device	0.279	0.721
J40-J47 Chronic lower respiratory diseases	0.280	0.720
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.281	0.719
Z95 Presence of cardiac and vascular implants and grafts	0.281	0.719
I25 Chronic ischaemic heart disease	0.282	0.718
I95-I99 Other and unspecified disorders of the circulatory system	0.282	0.718
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.282	0.718
C60-C63 Malignant neoplasms of male genital organs	0.283	0.717
Z98.0 Intestinal bypass and anastomosis status	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.283	0.717
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.285	0.715
N92 Excessive, frequent and irregular menstruation	0.286	0.714
Z51.9 Medical care, unspecified	0.286	0.714
K64 Haemorrhoids and perianal venous thrombosis	0.286	0.713
M75 Shoulder lesions	0.287	0.713
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.287	0.713
C51-C58 Malignant neoplasms of female genital organs	0.287	0.712
Z81 Family history of mental and behavioural disorders	0.289	0.711
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.290	0.710
N25-N29 Other disorders of kidney and ureter	0.291	0.709
M19 Other arthrosis	0.291	0.709
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.291	0.709
K02 Dental caries	0.291	0.709
Z40 Prophylactic surgery	0.292	0.708
Z42 Follow-up care involving plastic surgery	0.292	0.708
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.292	0.708
Z54 Convalescence	0.292	0.708
M86-M90 Other osteopathies	0.293	0.707
M91-M94 Chondropathies	0.293	0.707
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.293	0.707
M20 Acquired deformities of fingers and toes	0.293	0.707
K57.3 Diverticular disease of large intestine without perforation or abscess	0.294	0.706
Z43 Attention to artificial openings	0.294	0.706
R91 Abnormal findings on diagnostic imaging of lung	0.294	0.706
K31 Other diseases of stomach and duodenum	0.294	0.705
K65-K67 Diseases of peritoneum	0.295	0.705
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.295	0.705
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.296	0.704
C40-C41 Malignant neoplasms of bone and articular cartilage	0.296	0.704
H65-H75 Diseases of middle ear and mastoid	0.296	0.704
M16 Coxarthrosis [arthrosis of hip]	0.296	0.704
K60 Fissure and fistula of anal and rectal regions	0.296	0.704
R93 Abnormal findings on diagnostic imaging of other body structures	0.296	0.704
K23 Disorders of oesophagus in diseases classified elsewhere	0.297	0.703
K28 Gastrojejunal ulcer	0.297	0.703
E87 Other disorders of fluid, electrolyte and acid-base balance	0.298	0.702
M05-M14 Inflammatory polyarthropathies	0.298	0.702
C43-C44 Melanoma and other malignant neoplasms of skin	0.299	0.700
M45-M49 Spondylopathies	0.300	0.700
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.301	0.699
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.301	0.699
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.301	0.699
Chapter VI Diseases of the nervous system	0.302	0.698
C18 Malignant neoplasm of colon	0.302	0.698
M60-M63 Disorders of muscles	0.303	0.697
M80-M85 Disorders of bone density and structure	0.303	0.697
Chapter XII Diseases of the skin and subcutaneous tissue	0.303	0.697
K22.8 Other specified diseases of oesophagus	0.303	0.697
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.304	0.696
K55 Vascular disorders of intestine	0.304	0.696
K04 Diseases of pulp and periapical tissues	0.305	0.695
K62.5 Haemorrhage of anus and rectum	0.305	0.695
M00-M03 Infectious arthropathies	0.306	0.694
N00-N08 Glomerular diseases	0.308	0.692
K62.6 Ulcer of anus and rectum	0.308	0.692
K27 Peptic ulcer, site unspecified	0.309	0.690
K56.6 Other and unspecified intestinal obstruction	0.309	0.690
K40-K46 Hernia	0.310	0.690
Z51.6 Desensitisation to allergens	0.311	0.689
N39 Other disorders of urinary system	0.311	0.689
K62.3 Rectal prolapse	0.311	0.689
N80 Endometriosis	0.311	0.689
R50-R69 General symptoms and signs	0.311	0.689
Z93 Artificial opening status	0.311	0.688
Z46 Fitting and adjustment of other devices	0.312	0.688
Z41 Procedures for purposes other than remedying health state	0.312	0.688
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.313	0.687
J60-J70 Lung diseases due to external agents	0.313	0.687
J30-J39 Other diseases of upper respiratory tract	0.313	0.687
M50-M54 Other dorsopathies	0.314	0.686
J20-J22 Other acute lower respiratory infections	0.314	0.686
E20-E35 Disorders of other endocrine glands	0.314	0.685
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.315	0.685
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.315	0.685
W00-W19 Falls	0.315	0.685
N20-N23 Urolithiasis	0.316	0.684
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.316	0.684
K59.4 Anal spasm	0.317	0.683
M72 Fibroblastic disorders	0.317	0.683
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.318	0.682
C78.0 Secondary malignant neoplasm of lung	0.318	0.682
I05-I09 Chronic rheumatic heart diseases	0.318	0.682
K29.8 Duodenitis	0.318	0.682
Z85.5 Personal history of malignant neoplasm of urinary tract	0.319	0.681
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.319	0.681
K61 Abscess of anal and rectal regions	0.320	0.680
R95-R99 Ill-defined and unknown causes of mortality	0.320	0.679
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.321	0.679
R13 Dysphagia	0.323	0.677
K59.3 Megacolon, not elsewhere classified	0.323	0.677
N35 Urethral stricture	0.323	0.677
Z97 Presence of other devices	0.324	0.676
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.324	0.676
Z88.0 Personal history of allergy to penicillin	0.324	0.676
C78.7 Secondary malignant neoplasm of liver	0.326	0.674
Chapter V Mental and behavioural disorders	0.327	0.673
K62.7 Radiation proctitis	0.328	0.672
B35-B49 Mycoses	0.328	0.672
I00-I02 Acute rheumatic fever	0.328	0.671
K59.8 Other specified functional intestinal disorders	0.328	0.671
A30-A49 Other bacterial diseases	0.330	0.670
Z47 Other orthopaedic follow-up care	0.331	0.669
Z88.3 Personal history of allergy to other anti-infective agents	0.332	0.668
K35-K38 Diseases of appendix	0.333	0.667
I30-I52 Other forms of heart disease	0.333	0.667
I60-I69 Cerebrovascular diseases	0.334	0.666
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.336	0.664
K29.1 Other acute gastritis	0.336	0.664
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.336	0.663
H80-H83 Diseases of inner ear	0.337	0.663
Z91.5 Personal history of self-harm	0.337	0.663
N85 Other noninflammatory disorders of uterus, except cervix	0.337	0.663
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.337	0.663
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.337	0.662
K29.7 Gastritis, unspecified	0.338	0.662
K50 Crohn's disease [regional enteritis]	0.339	0.661
D70-D77 Other diseases of blood and blood-forming organs	0.339	0.661
C76 Malignant neoplasm of other and ill-defined sites	0.339	0.661
B50-B64 Protozoal diseases	0.339	0.660
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.340	0.660
Z87.6 Personal history of certain conditions arising in the perinatal period	0.341	0.659
K59.2 Neurogenic bowel, not elsewhere classified	0.341	0.659
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.342	0.658
B15-B19 Viral hepatitis	0.342	0.658
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.342	0.658
K62.2 Anal prolapse	0.343	0.657
D25 Leiomyoma of uterus	0.343	0.656
Z51.2 Other chemotherapy	0.344	0.656
N90 Other noninflammatory disorders of vulva and perineum	0.344	0.656
T36-T50 Poisoning by drugs, medicaments and biological substances	0.344	0.656
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.345	0.655
R47-R49 Symptoms and signs involving speech and voice	0.345	0.655
R21 Rash and other nonspecific skin eruption	0.346	0.654
K59.9 Functional intestinal disorder, unspecified	0.346	0.653
R19 Other symptoms and signs involving the digestive system and abdomen	0.347	0.653
K62.0 Anal polyp	0.347	0.653
K13 Other diseases of lip and oral mucosa	0.347	0.653
A50-A64 Infections with a predominantly sexual mode of transmission	0.348	0.652
K22.7 Barrett's oesophagus	0.348	0.652
Z88.7 Personal history of allergy to serum and vaccine	0.349	0.651
J00-J06 Acute upper respiratory infections	0.349	0.651
K59.1 Functional diarrhoea	0.350	0.650
Z98.8 Other specified postsurgical states	0.350	0.650
Z85.4 Personal history of malignant neoplasm of genital organs	0.350	0.649
Z96.8 Presence of other specified functional implants	0.351	0.649
H91 Other hearing loss	0.352	0.648
N36 Other disorders of urethra	0.352	0.648
Z96.0 Presence of urogenital implants	0.353	0.647
M18 Arthrosis of first carpometacarpal joint	0.353	0.647
K62.4 Stenosis of anus and rectum	0.353	0.647
Z88.2 Personal history of allergy to sulphonamides	0.353	0.647
Z87.0 Personal history of diseases of the respiratory system	0.353	0.646
K14 Diseases of tongue	0.353	0.646
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.354	0.646
C80 Malignant neoplasm without specification of site	0.354	0.645
K22.3 Perforation of oesophagus	0.355	0.645
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.355	0.645
A75-A79 Rickettsioses	0.355	0.645
A70-A74 Other diseases caused by chlamydiae	0.355	0.645
A20-A28 Certain zoonotic bacterial diseases	0.356	0.644
J90-J94 Other diseases of pleura	0.356	0.644
B85-B89 Pediculosis, acariasis and other infestations	0.356	0.644
Z80.8 Family history of malignant neoplasm of other organs or systems	0.356	0.644
I85 Oesophageal varices	0.356	0.644
Z51.4 Preparatory care for treatment, not elsewhere classified	0.356	0.643
A65-A69 Other spirochaetal diseases	0.357	0.643
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.357	0.642
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.358	0.642
M16.1 Other primary coxarthrosis	0.358	0.642
M70 Soft tissue disorders related to use, overuse and pressure	0.358	0.642
M17 Gonarthrosis [arthrosis of knee]	0.358	0.642
B99-B99 Other infectious diseases	0.358	0.642
A15-A19 Tuberculosis	0.358	0.641
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.358	0.641
B65-B83 Helminthiases	0.359	0.641
B25-B34 Other viral diseases	0.359	0.641
E10-E14 Diabetes mellitus	0.359	0.641
K62.9 Disease of anus and rectum, unspecified	0.359	0.641
Z08 Follow-up examination after treatment for malignant neoplasm	0.359	0.641
M23 Internal derangement of knee	0.359	0.641
M79.8 Other specified soft tissue disorders	0.359	0.640
B20-B24 Human immunodeficiency virus [HIV] disease	0.360	0.640
C15 Malignant neoplasm of oesophagus	0.360	0.640
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.360	0.640
N17 Acute renal failure	0.360	0.640
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.360	0.640
B90-B94 Sequelae of infectious and parasitic diseases	0.361	0.639
K22.5 Diverticulum of oesophagus, acquired	0.361	0.639
D80-D89 Certain disorders involving the immune mechanism	0.361	0.639
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.361	0.639
A80-A89 Viral infections of the central nervous system	0.362	0.638
N37 Urethral disorders in diseases classified elsewhere	0.362	0.638
N33 Bladder disorders in diseases classified elsewhere	0.362	0.638
K22.0 Achalasia of cardia	0.362	0.638
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.362	0.638
N82 Fistulae involving female genital tract	0.362	0.637
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.363	0.637
S50-S59 Injuries to the elbow and forearm	0.364	0.636
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.365	0.635
H60-H62 Diseases of external ear	0.365	0.635
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.365	0.635
Z92.6 Personal history of chemotherapy for neoplastic disease	0.365	0.635
Z96.5 Presence of tooth-root and mandibular implants	0.365	0.634
Z96.3 Presence of artificial larynx	0.366	0.634
M15 Polyarthrosis	0.366	0.634
N97 Female infertility	0.366	0.633
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.367	0.633
Z96.4 Presence of endocrine implants	0.367	0.633
Z96.9 Presence of functional implant, unspecified	0.367	0.633
E40-E46 Malnutrition	0.367	0.633
N89 Other noninflammatory disorders of vagina	0.368	0.632
N34 Urethritis and urethral syndrome	0.368	0.632
R30 Pain associated with micturition	0.368	0.632
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.368	0.632
M71 Other bursopathies	0.369	0.631
T20-T25 Burns and corrosions of external body surface, specified by site	0.369	0.631
Z87.8 Personal history of other specified conditions	0.369	0.631
K30 Dyspepsia	0.369	0.631
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.369	0.631
R10.3 Pain localised to other parts of lower abdomen	0.369	0.631
E50-E64 Other nutritional deficiencies	0.369	0.630
Z96.2 Presence of otological and audiological implants	0.369	0.630
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.370	0.630
I83 Varicose veins of lower extremities	0.370	0.630
R10.4 Other and unspecified abdominal pain	0.370	0.630
K56.5 Intestinal adhesions [bands] with obstruction	0.370	0.630
Z92.2 Personal history of long-term (current) use of other medicaments	0.370	0.630
N81 Female genital prolapse	0.370	0.630
R90 Abnormal findings on diagnostic imaging of central nervous system	0.371	0.629
Z85.3 Personal history of malignant neoplasm of breast	0.371	0.629
M73 Soft tissue disorders in diseases classified elsewhere	0.372	0.628
K05 Gingivitis and periodontal diseases	0.372	0.628
M34 Systemic sclerosis	0.373	0.627
Z12 Special screening examination for neoplasms	0.374	0.626
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.374	0.626
K57.1 Diverticular disease of small intestine without perforation or abscess	0.374	0.626
Z96.7 Presence of other bone and tendon implants	0.375	0.625
K06 Other disorders of gingiva and edentulous alveolar ridge	0.375	0.625
N98 Complications associated with artificial fertilisation	0.375	0.625
N96 Habitual aborter	0.375	0.625
N70-N77 Inflammatory diseases of female pelvic organs	0.375	0.624
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.376	0.624
K10 Other diseases of jaws	0.376	0.623
J80-J84 Other respiratory diseases principally affecting the interstitium	0.377	0.623
N32.8 Other specified disorders of bladder	0.377	0.623
V90-V94 Water transport accidents	0.377	0.623
M22 Disorders of patella	0.377	0.623
K22.4 Dyskinesia of oesophagus	0.377	0.623
K29.9 Gastroduodenitis, unspecified	0.377	0.623
N93 Other abnormal uterine and vaginal bleeding	0.377	0.623
I84 Haemorrhoids	0.377	0.623
D64 Other anaemias	0.377	0.623
E78.5 Hyperlipidaemia, unspecified	0.377	0.623
N91 Absent, scanty and rare menstruation	0.377	0.622
M76 Enthesopathies of lower limb, excluding foot	0.378	0.622
W75-W84 Other accidental threats to breathing	0.378	0.622
Z88.4 Personal history of allergy to anaesthetic agent	0.378	0.621
C78.4 Secondary malignant neoplasm of small intestine	0.379	0.621
X20-X29 Contact with venomous animals and plants	0.379	0.621
X60-X84 Intentional self-harm	0.379	0.621
C67 Malignant neoplasm of bladder	0.379	0.620
K22.9 Disease of oesophagus, unspecified	0.380	0.620
K57.2 Diverticular disease of large intestine with perforation and abscess	0.381	0.619
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.381	0.619
K11 Diseases of salivary glands	0.381	0.619
R14 Flatulence and related conditions	0.381	0.618
V80-V89 Other land transport accidents	0.381	0.618
K29.2 Alcoholic gastritis	0.382	0.618
K56.2 Volvulus	0.382	0.618
V01-V09 Pedestrian injured in transport accident	0.382	0.617
S70-S79 Injuries to the hip and thigh	0.382	0.617
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.382	0.617
Z88.6 Personal history of allergy to analgesic agent	0.382	0.617
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.383	0.617
Z91.7 Personal history of female genital mutilation	0.383	0.617
Z91.3 Personal history of unhealthy sleep-wake schedule	0.383	0.617
Z91.6 Personal history of other physical trauma	0.383	0.617
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.384	0.616
Z80.3 Family history of malignant neoplasm of breast	0.384	0.616
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.384	0.616
V40-V49 Car occupant injured in transport accident	0.384	0.616
Z91.2 Personal history of poor personal hygiene	0.384	0.616
J95-J99 Other diseases of the respiratory system	0.384	0.616
X40-X49 Accidental poisoning by and exposure to noxious substances	0.384	0.615
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.384	0.615
Z92.3 Personal history of irradiation	0.384	0.615
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.385	0.615
K63.8 Other specified diseases of intestine	0.385	0.615
K03 Other diseases of hard tissues of teeth	0.385	0.615
M33 Dermatopolymyositis	0.386	0.614
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.386	0.614
K57.0 Diverticular disease of small intestine with perforation and abscess	0.386	0.614
K07 Dentofacial anomalies [including malocclusion]	0.386	0.614
H30-H36 Disorders of choroid and retina	0.386	0.614
K29.3 Chronic superficial gastritis	0.387	0.613
Z86 Personal history of certain other diseases	0.387	0.613
R15 Faecal incontinence	0.387	0.613
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.388	0.612
M20.1 Hallux valgus (acquired)	0.388	0.612
Y35-Y36 Legal intervention and operations of war	0.389	0.611
X85-X99 Assault	0.389	0.611
W65-W74 Accidental drowning and submersion	0.389	0.611
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.389	0.611
X30-X39 Exposure to forces of nature	0.389	0.611
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.389	0.611
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.389	0.610
E65-E68 Obesity and other hyperalimentation	0.390	0.610
V70-V79 Bus occupant injured in transport accident	0.390	0.610
C50 Malignant neoplasm of breast	0.390	0.610
W20-W49 Exposure to inanimate mechanical forces	0.390	0.610
V95-V97 Air and space transport accidents	0.390	0.610
V98-V99 Other and unspecified transport accidents	0.390	0.610
K00 Disorders of tooth development and eruption	0.390	0.610
Y10-Y34 Event of undetermined intent	0.390	0.610
X00-X09 Exposure to smoke, fire and flames	0.390	0.610
R35 Polyuria	0.390	0.610
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.390	0.610
M21 Other acquired deformities of limbs	0.390	0.609
K56.4 Other impaction of intestine	0.391	0.609
K29.5 Chronic gastritis, unspecified	0.391	0.609
D23 Other benign neoplasms of skin	0.391	0.609
D11 Benign neoplasm of major salivary glands	0.391	0.609
D55-D59 Haemolytic anaemias	0.391	0.609
K29.4 Chronic atrophic gastritis	0.391	0.609
K12 Stomatitis and related lesions	0.391	0.609
X10-X19 Contact with heat and hot substances	0.392	0.608
N92.0 Excessive and frequent menstruation with regular cycle	0.393	0.607
K01 Embedded and impacted teeth	0.393	0.607
Z88.5 Personal history of allergy to narcotic agent	0.393	0.607
S10-S19 Injuries to the neck	0.393	0.607
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.393	0.607
R34 Anuria and oliguria	0.393	0.607
X50-X57 Overexertion, travel and privation	0.393	0.607
X58-X59 Accidental exposure to other and unspecified factors	0.393	0.606
Y00-Y09 Assault	0.394	0.606
M77 Other enthesopathies	0.394	0.606
K63.4 Enteroptosis	0.394	0.605
I25.1 Atherosclerotic heart disease	0.394	0.605
Z98.1 Arthrodesis status	0.395	0.605
I21 Acute myocardial infarction	0.395	0.605
K63.0 Abscess of intestine	0.395	0.604
I80 Phlebitis and thrombophlebitis	0.396	0.604
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.396	0.604
Z80.6 Family history of leukaemia	0.396	0.604
N88 Other noninflammatory disorders of cervix uteri	0.396	0.604
K29.0 Acute haemorrhagic gastritis	0.397	0.603
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.397	0.603
J47 Bronchiectasis	0.397	0.603
M75.0 Adhesive capsulitis of shoulder	0.398	0.602
J44 Other chronic obstructive pulmonary disease	0.398	0.602
K09 Cysts of oral region, not elsewhere classified	0.398	0.602
D36 Benign neoplasm of other and unspecified sites	0.398	0.602
D17 Benign lipomatous neoplasm	0.398	0.602
R92 Abnormal findings on diagnostic imaging of breast	0.398	0.602
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.398	0.602
K63.3 Ulcer of intestine	0.399	0.601
Z85.0 Personal history of malignant neoplasm of digestive organs	0.399	0.601
V20-V29 Motorcycle rider injured in transport accident	0.399	0.601
C17 Malignant neoplasm of small intestine	0.399	0.601
W50-W64 Exposure to animate mechanical forces	0.399	0.601
Z48.0 Attention to surgical dressings and sutures	0.399	0.601
M24 Other specific joint derangements	0.399	0.601
C78.2 Secondary malignant neoplasm of pleura	0.400	0.600
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.400	0.600
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.400	0.600

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations