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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4496023
log Bayes Factor = 22.4402
Chromosome 14   position 21,303,605  (GRCh37) Explore rs4496023 on Ensembl!
Variant rs4496023 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
F32 Depressive episode
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.002 0.000
F32.9 Depressive episode, unspecified
0.998 0.002 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.998 0.002 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.996 0.004 0.000
I35 Nonrheumatic aortic valve disorders
0.994 0.006 0.000
G40-G47 Episodic and paroxysmal disorders
0.993 0.007 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.992 0.008 0.000
I44 Atrioventricular and left bundle-branch block
0.991 0.009 0.000
E10-E14 Diabetes mellitus
0.991 0.009 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.983 0.017 0.000
G40 Epilepsy
0.980 0.020 0.000
F10.1 Harmful use
0.978 0.022 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.972 0.028 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.971 0.029 0.000
S20-S29 Injuries to the thorax
0.971 0.029 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.970 0.030 0.000
Chapter I Certain infectious and parasitic diseases
0.967 0.033 0.000
I35.0 Aortic (valve) stenosis
0.966 0.034 0.000
G40.9 Epilepsy, unspecified
0.966 0.034 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.959 0.041 0.000
F41 Other anxiety disorders
0.958 0.042 0.000
F17.1 Harmful use
0.955 0.045 0.000
G90-G99 Other disorders of the nervous system
0.954 0.046 0.000
E10 Insulin-dependent diabetes mellitus
0.954 0.046 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.953 0.047 0.000
I44.7 Left bundle-branch block, unspecified
0.947 0.053 0.000
J00-J06 Acute upper respiratory infections
0.943 0.057 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.941 0.059 0.000
F33 Recurrent depressive disorder
0.939 0.061 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.937 0.063 0.000
A30-A49 Other bacterial diseases
0.936 0.064 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.934 0.066 0.000
F10.0 Acute intoxication
0.930 0.070 0.000
F41.2 Mixed anxiety and depressive disorder
0.926 0.074 0.000
I51 Complications and ill-defined descriptions of heart disease
0.922 0.078 0.000
Chapter XX External causes of morbidity and mortality
0.920 0.080 0.000
I74 Arterial embolism and thrombosis
0.920 0.080 0.000
G20-G26 Extrapyramidal and movement disorders
0.917 0.083 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.916 0.084 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.910 0.090 0.000
I35.1 Aortic (valve) insufficiency
0.905 0.095 0.000
E14 Unspecified diabetes mellitus
0.901 0.099 0.000
I26 Pulmonary embolism
0.900 0.100 0.000
I73 Other peripheral vascular diseases
0.897 0.103 0.000
G47 Sleep disorders
0.895 0.105 0.000
I50 Heart failure
0.887 0.113 0.000
A41 Other septicaemia
0.881 0.119 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.876 0.124 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.873 0.127 0.000
E70-E90 Metabolic disorders
0.873 0.127 0.000
J95-J99 Other diseases of the respiratory system
0.873 0.127 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.867 0.133 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.865 0.135 0.000
L90 Atrophic disorders of skin
0.865 0.135 0.000
E10.5 With peripheral circulatory complications
0.862 0.138 0.000
I44.0 Atrioventricular block, first degree
0.861 0.139 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.859 0.141 0.000
S22.3 Fracture of rib
0.858 0.142 0.000
I73.9 Peripheral vascular disease, unspecified
0.855 0.145 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.855 0.145 0.000
I51.7 Cardiomegaly
0.854 0.146 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.854 0.146 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.853 0.147 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.852 0.148 0.000
I46 Cardiac arrest
0.850 0.150 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.850 0.150 0.000
I44.3 Other and unspecified atrioventricular block
0.849 0.151 0.000
E11 Non-insulin-dependent diabetes mellitus
0.848 0.152 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.846 0.154 0.000
J00 Acute nasopharyngitis [common cold]
0.845 0.155 0.000
A41.9 Septicaemia, unspecified
0.843 0.157 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.839 0.161 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.839 0.161 0.000
G25 Other extrapyramidal and movement disorders
0.833 0.167 0.000
E20-E35 Disorders of other endocrine glands
0.833 0.167 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.833 0.167 0.000
S27 Injury of other and unspecified intrathoracic organs
0.832 0.168 0.000
J42 Unspecified chronic bronchitis
0.832 0.168 0.000
E14.9 Without complications
0.831 0.169 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.831 0.169 0.000
I44.1 Atrioventricular block, second degree
0.830 0.170 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.829 0.171 0.000
A49 Bacterial infection of unspecified site
0.828 0.171 0.000
E10.2 With renal complications
0.827 0.173 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.826 0.174 0.000
F33.9 Recurrent depressive disorder, unspecified
0.825 0.175 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.824 0.176 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.824 0.176 0.000
S80-S89 Injuries to the knee and lower leg
0.823 0.177 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.822 0.178 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.819 0.181 0.000
S00-S09 Injuries to the head
0.819 0.181 0.000
I74.5 Embolism and thrombosis of iliac artery
0.814 0.186 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.813 0.187 0.000
F41.1 Generalised anxiety disorder
0.813 0.187 0.000
J09-J18 Influenza and pneumonia
0.811 0.189 0.000
Chapter VII Diseases of the eye and adnexa
0.809 0.191 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.808 0.192 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.805 0.195 0.000
S22.30 Fracture of rib (closed)
0.804 0.196 0.000
E10.4 With neurological complications
0.803 0.197 0.000
L20-L30 Dermatitis and eczema
0.803 0.197 0.000
E65-E68 Obesity and other hyperalimentation
0.801 0.199 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.796 0.203 0.000
F10.2 Dependence syndrome
0.796 0.204 0.000
G93 Other disorders of brain
0.795 0.205 0.000
F60-F69 Disorders of adult personality and behaviour
0.794 0.206 0.000
F32.1 Moderate depressive episode
0.794 0.206 0.000
S22.4 Multiple fractures of ribs
0.793 0.207 0.000
I50.1 Left ventricular failure
0.790 0.210 0.000
J06.9 Acute upper respiratory infection, unspecified
0.790 0.210 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.788 0.212 0.000
L89 Decubitus ulcer
0.788 0.212 0.000
E50-E64 Other nutritional deficiencies
0.786 0.214 0.000
L84 Corns and callosities
0.786 0.214 0.000
F32.0 Mild depressive episode
0.784 0.216 0.000
I34 Nonrheumatic mitral valve disorders
0.783 0.217 0.000
E10.3 With ophthalmic complications
0.782 0.218 0.000
F80-F89 Disorders of psychological development
0.782 0.218 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.780 0.220 0.000
I71 Aortic aneurysm and dissection
0.778 0.222 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.778 0.222 0.000
F31 Bipolar affective disorder
0.778 0.222 0.000
I05-I09 Chronic rheumatic heart diseases
0.776 0.224 0.000
F41.9 Anxiety disorder, unspecified
0.774 0.226 0.000
I31 Other diseases of pericardium
0.773 0.227 0.000
E16 Other disorders of pancreatic internal secretion
0.773 0.227 0.000
F10.4 Withdrawal state with delirium
0.769 0.231 0.000
F43 Reaction to severe stress, and adjustment disorders
0.769 0.231 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.769 0.231 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.767 0.233 0.000
I78 Diseases of capillaries
0.767 0.233 0.000
D70 Agranulocytosis
0.767 0.233 0.000
L08 Other local infections of skin and subcutaneous tissue
0.766 0.234 0.000
S70-S79 Injuries to the hip and thigh
0.766 0.234 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.765 0.235 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.764 0.236 0.000
G47.9 Sleep disorder, unspecified
0.763 0.236 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.763 0.237 0.000
I30 Acute pericarditis
0.763 0.237 0.000
S50-S59 Injuries to the elbow and forearm
0.763 0.237 0.000
T79-T79 Certain early complications of trauma
0.761 0.239 0.000
M50-M54 Other dorsopathies
0.759 0.241 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.758 0.241 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.757 0.243 0.000
I49 Other cardiac arrhythmias
0.757 0.243 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.754 0.246 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.754 0.246 0.000
B35-B49 Mycoses
0.753 0.247 0.000
A00-A09 Intestinal infectious diseases
0.753 0.247 0.000
Chapter XXII Codes for special purposes
0.752 0.248 0.000
G44 Other headache syndromes
0.752 0.248 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.751 0.249 0.000
I51.6 Cardiovascular disease, unspecified
0.748 0.252 0.000
S22.5 Flail chest
0.748 0.252 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.747 0.253 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.745 0.254 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.745 0.255 0.000
I35.9 Aortic valve disorder, unspecified
0.744 0.256 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.744 0.256 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.744 0.256 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.743 0.257 0.000
I95 Hypotension
0.742 0.258 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.742 0.258 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.742 0.258 0.000
E83 Disorders of mineral metabolism
0.741 0.259 0.000
G90 Disorders of autonomic nervous system
0.741 0.259 0.000
T66-T78 Other and unspecified effects of external causes
0.740 0.260 0.000
L90.5 Scar conditions and fibrosis of skin
0.735 0.265 0.000
W00-W19 Falls
0.734 0.266 0.000
S32 Fracture of lumbar spine and pelvis
0.732 0.268 0.000
G20 Parkinson's disease
0.732 0.268 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.731 0.269 0.000
L60-L75 Disorders of skin appendages
0.731 0.269 0.000
F10.3 Withdrawal state
0.730 0.270 0.000
D75 Other diseases of blood and blood-forming organs
0.730 0.270 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.729 0.271 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.728 0.272 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.728 0.272 0.000
I46.0 Cardiac arrest with successful resuscitation
0.728 0.272 0.000
G70-G73 Diseases of myoneural junction and muscle
0.728 0.272 0.000
I50.0 Congestive heart failure
0.728 0.272 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.724 0.276 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.724 0.276 0.000
L50-L54 Urticaria and erythema
0.719 0.280 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.717 0.283 0.000
F34 Persistent mood [affective] disorders
0.717 0.283 0.000
F30 Manic episode
0.717 0.283 0.000
F39 Unspecified mood [affective] disorder
0.717 0.283 0.000
F32.8 Other depressive episodes
0.717 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.717 0.283 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.717 0.283 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.717 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.717 0.283 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.717 0.283 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.717 0.283 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.717 0.283 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.717 0.283 0.000
F11 Mental and behavioural disorders due to use of opioids
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
L10-L14 Bullous disorders
0.715 0.284 0.000
M80-M85 Disorders of bone density and structure
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
F10.9 Unspecified mental and behavioural disorder
0.714 0.286 0.000
F10.8 Other mental and behavioural disorders
0.714 0.286 0.000
F10.7 Residual and late-onset psychotic disorder
0.714 0.286 0.000
F10.6 Amnesic syndrome
0.714 0.286 0.000
F10.5 Psychotic disorder
0.714 0.286 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.714 0.286 0.000
D68 Other coagulation defects
0.714 0.286 0.000
A49.8 Other bacterial infections of unspecified site
0.714 0.286 0.000
I35.8 Other aortic valve disorders
0.713 0.287 0.000
Y40 Systemic antibiotics
0.713 0.287 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.712 0.288 0.000
G41 Status epilepticus
0.712 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.288 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.711 0.289 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.711 0.289 0.000
L94 Other localised connective tissue disorders
0.711 0.289 0.000
L93 Lupus erythematosus
0.711 0.289 0.000
L87 Transepidermal elimination disorders
0.711 0.289 0.000
L88 Pyoderma gangrenosum
0.711 0.289 0.000
L86 Keratoderma in diseases classified elsewhere
0.711 0.289 0.000
L83 Acanthosis nigricans
0.711 0.289 0.000
L80 Vitiligo
0.711 0.289 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.711 0.289 0.000
I44.6 Other and unspecified fascicular block
0.710 0.290 0.000
I44.5 Left posterior fascicular block
0.710 0.290 0.000
I44.4 Left anterior fascicular block
0.710 0.290 0.000
E13 Other specified diabetes mellitus
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.710 0.290 0.000
L40-L45 Papulosquamous disorders
0.710 0.290 0.000
I95.9 Hypotension, unspecified
0.709 0.291 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.707 0.293 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.706 0.294 0.000
I70 Atherosclerosis
0.706 0.294 0.000
E16.2 Hypoglycaemia, unspecified
0.705 0.295 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.705 0.295 0.000
I72 Other aneurysm
0.705 0.295 0.000
D80-D89 Certain disorders involving the immune mechanism
0.705 0.295 0.000
E11.4 With neurological complications
0.704 0.296 0.000
D50-D53 Nutritional anaemias
0.703 0.297 0.000
G40.8 Other epilepsy
0.702 0.298 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.702 0.298 0.000
G40.5 Special epileptic syndromes
0.702 0.298 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.702 0.298 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.702 0.298 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.702 0.298 0.000
J04 Acute laryngitis and tracheitis
0.702 0.298 0.000
J46 Status asthmaticus
0.700 0.299 0.000
D69 Purpura and other haemorrhagic conditions
0.700 0.300 0.000
L85 Other epidermal thickening
0.698 0.302 0.000
F48 Other neurotic disorders
0.697 0.303 0.000
F44 Dissociative [conversion] disorders
0.697 0.303 0.000
F42 Obsessive-compulsive disorder
0.697 0.303 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.696 0.304 0.000
G91 Hydrocephalus
0.696 0.304 0.000
F17.9 Unspecified mental and behavioural disorder
0.696 0.304 0.000
F17.8 Other mental and behavioural disorders
0.696 0.304 0.000
F17.7 Residual and late-onset psychotic disorder
0.696 0.304 0.000
F17.6 Amnesic syndrome
0.696 0.304 0.000
F17.5 Psychotic disorder
0.696 0.304 0.000
F17.4 Withdrawal state with delirium
0.696 0.304 0.000
F17.3 Withdrawal state
0.696 0.304 0.000
F17.0 Acute intoxication
0.696 0.304 0.000
S29 Other and unspecified injuries of thorax
0.696 0.304 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.696 0.304 0.000
S26 Injury of heart
0.696 0.304 0.000
S25 Injury of blood vessels of thorax
0.696 0.304 0.000
S24 Injury of nerves and spinal cord at thorax level
0.696 0.304 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.696 0.304 0.000
S21 Open wound of thorax
0.696 0.304 0.000
L05 Pilonidal cyst
0.696 0.304 0.000
M20-M25 Other joint disorders
0.696 0.304 0.000
H53-H54 Visual disturbances and blindness
0.695 0.305 0.000
M86-M90 Other osteopathies
0.695 0.305 0.000
E11.5 With peripheral circulatory complications
0.695 0.305 0.000
T39.0 Salicylates
0.695 0.305 0.000
B99-B99 Other infectious diseases
0.693 0.306 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.693 0.306 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.693 0.306 0.000
B65-B83 Helminthiases
0.693 0.306 0.000
B50-B64 Protozoal diseases
0.693 0.306 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.693 0.306 0.000
A80-A89 Viral infections of the central nervous system
0.693 0.306 0.000
A75-A79 Rickettsioses
0.693 0.306 0.000
A70-A74 Other diseases caused by chlamydiae
0.693 0.306 0.000
A65-A69 Other spirochaetal diseases
0.693 0.306 0.000
A20-A28 Certain zoonotic bacterial diseases
0.693 0.306 0.000
A15-A19 Tuberculosis
0.693 0.306 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.693 0.306 0.000
L90.0 Lichen sclerosus et atrophicus
0.693 0.307 0.000
S27.0 Traumatic pneumothorax
0.693 0.307 0.000
G25.3 Myoclonus
0.692 0.307 0.000
S22.40 Multiple fractures of ribs (closed)
0.692 0.308 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.690 0.310 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.689 0.311 0.000
J90-J94 Other diseases of pleura
0.687 0.312 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.687 0.313 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.313 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.687 0.313 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.687 0.313 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.687 0.313 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.687 0.313 0.000
T36 Poisoning by systemic antibiotics
0.687 0.313 0.000
F41.8 Other specified anxiety disorders
0.687 0.313 0.000
F41.3 Other mixed anxiety disorders
0.687 0.313 0.000
G47.3 Sleep apnoea
0.687 0.313 0.000
E11.2 With renal complications
0.686 0.313 0.000
M54 Dorsalgia
0.686 0.314 0.000
T90 Sequelae of injuries of head
0.685 0.315 0.000
E10.1 With ketoacidosis
0.685 0.315 0.000
B25-B34 Other viral diseases
0.685 0.315 0.000
E10.8 With unspecified complications
0.684 0.316 0.000
E10.7 With multiple complications
0.684 0.316 0.000
E10.6 With other specified complications
0.684 0.316 0.000
E10.0 With coma
0.684 0.316 0.000
G96 Other disorders of central nervous system
0.684 0.316 0.000
G95 Other diseases of spinal cord
0.684 0.316 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.684 0.316 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G92 Toxic encephalopathy
0.684 0.316 0.000
G37 Other demyelinating diseases of central nervous system
0.684 0.316 0.000
I34.1 Mitral (valve) prolapse
0.684 0.316 0.000
S81 Open wound of lower leg
0.683 0.317 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.683 0.317 0.000
J60-J70 Lung diseases due to external agents
0.683 0.317 0.000
S22.2 Fracture of sternum
0.682 0.318 0.000
S40-S49 Injuries to the shoulder and upper arm
0.682 0.318 0.000
I44.2 Atrioventricular block, complete
0.678 0.322 0.000
I77 Other disorders of arteries and arterioles
0.678 0.322 0.000
E86 Volume depletion
0.678 0.322 0.000
S22.0 Fracture of thoracic vertebra
0.677 0.323 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.676 0.324 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.676 0.324 0.000
J01 Acute sinusitis
0.676 0.324 0.000
S01 Open wound of head
0.675 0.325 0.000
D55-D59 Haemolytic anaemias
0.675 0.325 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.674 0.326 0.000
B15-B19 Viral hepatitis
0.674 0.326 0.000
F33.8 Other recurrent depressive disorders
0.673 0.327 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.673 0.327 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.673 0.327 0.000
E83.1 Disorders of iron metabolism
0.673 0.327 0.000
S20 Superficial injury of thorax
0.672 0.328 0.000
I28 Other diseases of pulmonary vessels
0.672 0.328 0.000
W20-W49 Exposure to inanimate mechanical forces
0.672 0.328 0.000
Y52 Agents primarily affecting the cardiovascular system
0.671 0.329 0.000
A48 Other bacterial diseases, not elsewhere classified
0.671 0.329 0.000
A44 Bartonellosis
0.671 0.329 0.000
A43 Nocardiosis
0.671 0.329 0.000
A42 Actinomycosis
0.671 0.329 0.000
A40 Streptococcal septicaemia
0.671 0.329 0.000
A39 Meningococcal infection
0.671 0.329 0.000
A37 Whooping cough
0.671 0.329 0.000
A36 Diphtheria
0.671 0.329 0.000
A32 Listeriosis
0.671 0.329 0.000
A31 Infection due to other mycobacteria
0.671 0.329 0.000
A30 Leprosy [Hansen's disease]
0.671 0.329 0.000
A46 Erysipelas
0.671 0.329 0.000
A38 Scarlet fever
0.671 0.329 0.000
A35 Other tetanus
0.671 0.329 0.000
A34 Obstetrical tetanus
0.671 0.329 0.000
A33 Tetanus neonatorum
0.671 0.329 0.000
A49.0 Staphylococcal infection, unspecified
0.671 0.329 0.000
J14 Pneumonia due to Haemophilus influenzae
0.670 0.330 0.000
S22.9 Fracture of bony thorax, part unspecified
0.670 0.330 0.000
S22.8 Fracture of other parts of bony thorax
0.670 0.330 0.000
S22.1 Multiple fractures of thoracic spine
0.670 0.330 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.669 0.331 0.000
G93.0 Cerebral cysts
0.669 0.331 0.000
L81 Other disorders of pigmentation
0.669 0.331 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.668 0.332 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.668 0.332 0.000
S60-S69 Injuries to the wrist and hand
0.667 0.333 0.000
E14.3 With ophthalmic complications
0.666 0.334 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.665 0.335 0.000
S27.1 Traumatic haemothorax
0.664 0.336 0.000
I49.8 Other specified cardiac arrhythmias
0.664 0.336 0.000
G25.0 Essential tremor
0.663 0.337 0.000
I51.9 Heart disease, unspecified
0.663 0.337 0.000
T63 Toxic effect of contact with venomous animals
0.662 0.338 0.000
I51.5 Myocardial degeneration
0.661 0.339 0.000
I51.4 Myocarditis, unspecified
0.661 0.339 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.661 0.339 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.661 0.339 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.661 0.339 0.000
I51.0 Cardiac septal defect, acquired
0.661 0.339 0.000
E66 Obesity
0.660 0.340 0.000
X60-X84 Intentional self-harm
0.660 0.340 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.660 0.340 0.000
Y35-Y36 Legal intervention and operations of war
0.660 0.340 0.000
Y10-Y34 Event of undetermined intent
0.660 0.340 0.000
Y00-Y09 Assault
0.660 0.340 0.000
X85-X99 Assault
0.660 0.340 0.000
X50-X57 Overexertion, travel and privation
0.660 0.340 0.000
X30-X39 Exposure to forces of nature
0.660 0.340 0.000
X20-X29 Contact with venomous animals and plants
0.660 0.340 0.000
X10-X19 Contact with heat and hot substances
0.660 0.340 0.000
X00-X09 Exposure to smoke, fire and flames
0.660 0.340 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.660 0.340 0.000
W75-W84 Other accidental threats to breathing
0.660 0.340 0.000
W65-W74 Accidental drowning and submersion
0.660 0.340 0.000
W50-W64 Exposure to animate mechanical forces
0.660 0.340 0.000
V98-V99 Other and unspecified transport accidents
0.660 0.340 0.000
V95-V97 Air and space transport accidents
0.660 0.340 0.000
V90-V94 Water transport accidents
0.660 0.340 0.000
V80-V89 Other land transport accidents
0.660 0.340 0.000
V70-V79 Bus occupant injured in transport accident
0.660 0.340 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.660 0.340 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.660 0.340 0.000
V40-V49 Car occupant injured in transport accident
0.660 0.340 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.660 0.340 0.000
V01-V09 Pedestrian injured in transport accident
0.660 0.340 0.000
G30-G32 Other degenerative diseases of the nervous system
0.659 0.340 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.659 0.341 0.000
I74.8 Embolism and thrombosis of other arteries
0.659 0.341 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.659 0.341 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.659 0.341 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.659 0.341 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.659 0.341 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.659 0.341 0.000
T51 Toxic effect of alcohol
0.658 0.341 0.000
L27 Dermatitis due to substances taken internally
0.657 0.343 0.000
G24 Dystonia
0.657 0.343 0.000
G23 Other degenerative diseases of basal ganglia
0.657 0.343 0.000
G21 Secondary Parkinsonism
0.657 0.343 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.657 0.343 0.000
G22 Parkinsonism in diseases classified elsewhere
0.657 0.343 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.657 0.343 0.000
L04 Acute lymphadenitis
0.656 0.343 0.000
L01 Impetigo
0.656 0.343 0.000
L00 Staphylococcal scalded skin syndrome
0.656 0.343 0.000
V20-V29 Motorcycle rider injured in transport accident
0.656 0.344 0.000
J98 Other respiratory disorders
0.656 0.344 0.000
I38 Endocarditis, valve unspecified
0.656 0.344 0.000
V10-V19 Pedal cyclist injured in transport accident
0.656 0.344 0.000
L91 Hypertrophic disorders of skin
0.655 0.345 0.000
L98.0 Pyogenic granuloma
0.653 0.347 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.653 0.347 0.000
Chapter VIII Diseases of the ear and mastoid process
0.653 0.347 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.652 0.348 0.000
M91-M94 Chondropathies
0.651 0.349 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.648 0.352 0.000
S05 Injury of eye and orbit
0.646 0.354 0.000
F60 Specific personality disorders
0.646 0.354 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.646 0.354 0.000
E14.8 With unspecified complications
0.646 0.354 0.000
E14.7 With multiple complications
0.646 0.354 0.000
E14.6 With other specified complications
0.646 0.354 0.000
E14.5 With peripheral circulatory complications
0.646 0.354 0.000
E14.4 With neurological complications
0.646 0.354 0.000
E14.2 Withrenal complications
0.646 0.354 0.000
E14.1 With ketoacidosis
0.646 0.354 0.000
E14.0 With coma
0.646 0.354 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.646 0.354 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.645 0.355 0.000
S06 Intracranial injury
0.645 0.355 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.645 0.355 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.644 0.356 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.644 0.356 0.000
I73.8 Other specified peripheral vascular diseases
0.643 0.357 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.643 0.357 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.642 0.358 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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