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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs45565837
log Bayes Factor = 23.5217
Chromosome 6   position 31,694,859  (GRCh37) Explore rs45565837 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
J45 Asthma
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
H36 Retinal disorders in diseases classified elsewhere
0.997 0.003 0.000
H36.0 Diabetic retinopathy
0.997 0.003 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.993 0.007 0.000
E10.1 With ketoacidosis
0.987 0.013 0.000
E14 Unspecified diabetes mellitus
0.980 0.020 0.000
J30-J39 Other diseases of upper respiratory tract
0.980 0.020 0.000
E10.4 With neurological complications
0.973 0.027 0.000
E11 Non-insulin-dependent diabetes mellitus
0.971 0.029 0.000
H25-H28 Disorders of lens
0.971 0.029 0.000
Chapter VI Diseases of the nervous system
0.964 0.036 0.000
Chapter XX External causes of morbidity and mortality
0.961 0.039 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.959 0.041 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.946 0.054 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.945 0.055 0.000
J33 Nasal polyp
0.944 0.056 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.943 0.057 0.000
H26 Other cataract
0.931 0.069 0.000
E11.4 With neurological complications
0.926 0.074 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.921 0.079 0.000
E10.5 With peripheral circulatory complications
0.918 0.082 0.000
E14.9 Without complications
0.918 0.082 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.915 0.085 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.915 0.085 0.000
J33.9 Nasal polyp, unspecified
0.914 0.086 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.907 0.093 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.904 0.096 0.000
J00-J06 Acute upper respiratory infections
0.894 0.106 0.000
E10.2 With renal complications
0.890 0.110 0.000
O80-O84 Delivery
0.884 0.116 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.878 0.122 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.875 0.124 0.000
Chapter V Mental and behavioural disorders
0.875 0.125 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.875 0.125 0.000
O80 Single spontaneous delivery
0.869 0.131 0.000
E14.3 With ophthalmic complications
0.865 0.135 0.000
H26.4 After-cataract
0.865 0.135 0.000
H43-H45 Disorders of vitreous body and globe
0.864 0.136 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.863 0.137 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.860 0.139 0.000
O80.0 Spontaneous vertex delivery
0.860 0.140 0.000
L08 Other local infections of skin and subcutaneous tissue
0.860 0.140 0.000
Chapter XXII Codes for special purposes
0.855 0.145 0.000
E11.5 With peripheral circulatory complications
0.855 0.145 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.854 0.146 0.000
H26.9 Cataract, unspecified
0.853 0.147 0.000
E10.0 With coma
0.850 0.150 0.000
J42 Unspecified chronic bronchitis
0.845 0.155 0.000
L20-L30 Dermatitis and eczema
0.844 0.156 0.000
M65-M68 Disorders of synovium and tendon
0.842 0.158 0.000
J60-J70 Lung diseases due to external agents
0.837 0.163 0.000
J34 Other disorders of nose and nasal sinuses
0.835 0.165 0.000
E14.6 With other specified complications
0.830 0.170 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.830 0.170 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.827 0.173 0.000
H35 Other retinal disorders
0.821 0.179 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.821 0.179 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.820 0.180 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.819 0.181 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.817 0.183 0.000
Y40 Systemic antibiotics
0.813 0.187 0.000
M86-M90 Other osteopathies
0.812 0.188 0.000
J44 Other chronic obstructive pulmonary disease
0.811 0.189 0.000
G82 Paraplegia and tetraplegia
0.805 0.195 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.805 0.195 0.000
M13 Other arthritis
0.802 0.198 0.000
E11.1 With ketoacidosis
0.800 0.200 0.000
J46 Status asthmaticus
0.797 0.203 0.000
Y52 Agents primarily affecting the cardiovascular system
0.796 0.204 0.000
M14 Arthropathies in other diseases classified elsewhere
0.795 0.205 0.000
H43 Disorders of vitreous body
0.795 0.205 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.793 0.207 0.000
S00-S09 Injuries to the head
0.793 0.207 0.000
G90-G99 Other disorders of the nervous system
0.788 0.212 0.000
H25 Senile cataract
0.785 0.215 0.000
E16 Other disorders of pancreatic internal secretion
0.785 0.215 0.000
X60-X84 Intentional self-harm
0.780 0.220 0.000
H53-H54 Visual disturbances and blindness
0.778 0.222 0.000
J33.0 Polyp of nasal cavity
0.777 0.223 0.000
M05 Seropositive rheumatoid arthritis
0.774 0.226 0.000
J38.7 Other diseases of larynx
0.774 0.226 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.773 0.227 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.773 0.227 0.000
L03 Cellulitis
0.772 0.228 0.000
G82.2 Paraplegia, unspecified
0.771 0.229 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.769 0.231 0.000
J09-J18 Influenza and pneumonia
0.769 0.231 0.000
M06.0 Seronegative rheumatoid arthritis
0.767 0.233 0.000
E11.0 With coma
0.765 0.235 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.765 0.235 0.000
H27 Other disorders of lens
0.761 0.239 0.000
H10-H13 Disorders of conjunctiva
0.760 0.240 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.759 0.241 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.758 0.242 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.757 0.243 0.000
L30 Other dermatitis
0.756 0.244 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.755 0.245 0.000
J30 Vasomotor and allergic rhinitis
0.747 0.253 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.746 0.254 0.000
G59.0 Diabetic mononeuropathy
0.745 0.255 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.745 0.255 0.000
S40-S49 Injuries to the shoulder and upper arm
0.745 0.255 0.000
E11.6 With other specified complications
0.743 0.257 0.000
M67 Other disorders of synovium and tendon
0.743 0.257 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.742 0.258 0.000
G70-G73 Diseases of myoneural junction and muscle
0.740 0.260 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.740 0.260 0.000
H55-H59 Other disorders of eye and adnexa
0.740 0.260 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.740 0.260 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.737 0.262 0.000
S06 Intracranial injury
0.737 0.263 0.000
E11.3 With ophthalmic complications
0.737 0.263 0.000
E40-E46 Malnutrition
0.736 0.264 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.735 0.264 0.000
F03 Unspecified dementia
0.735 0.265 0.000
E13 Other specified diabetes mellitus
0.734 0.266 0.000
T43.2 Other and unspecified antidepressants
0.730 0.270 0.000
J34.3 Hypertrophy of nasal turbinates
0.730 0.270 0.000
M80-M85 Disorders of bone density and structure
0.729 0.270 0.000
T79-T79 Certain early complications of trauma
0.729 0.271 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.728 0.272 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.727 0.273 0.000
J38.4 Oedema of larynx
0.726 0.274 0.000
H34 Retinal vascular occlusions
0.726 0.274 0.000
G63.2 Diabetic polyneuropathy
0.725 0.275 0.000
H43.1 Vitreous haemorrhage
0.724 0.276 0.000
W50-W64 Exposure to animate mechanical forces
0.724 0.276 0.000
G40-G47 Episodic and paroxysmal disorders
0.723 0.277 0.000
W00-W19 Falls
0.722 0.278 0.000
F01 Vascular dementia
0.722 0.278 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.722 0.278 0.000
E16.2 Hypoglycaemia, unspecified
0.721 0.279 0.000
M11 Other crystal arthropathies
0.721 0.279 0.000
M07 Psoriatic and enteropathic arthropathies
0.720 0.280 0.000
Y57 Other and unspecified drugs and medicaments
0.719 0.280 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.717 0.283 0.000
Chapter VIII Diseases of the ear and mastoid process
0.717 0.283 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
J45.8 Mixed asthma
0.717 0.283 0.000
J45.1 Nonallergic asthma
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.717 0.283 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.717 0.283 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.283 0.000
M06.4 Inflammatory polyarthropathy
0.716 0.283 0.000
M06.3 Rheumatoid nodule
0.716 0.283 0.000
M06.2 Rheumatoid bursitis
0.716 0.283 0.000
M06.1 Adult-onset Still's disease
0.716 0.283 0.000
M12 Other specific arthropathies
0.716 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.283 0.000
M08 Juvenile arthritis
0.716 0.283 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
H54 Blindness and low vision
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.716 0.284 0.000
H31 Other disorders of choroid
0.716 0.284 0.000
H30 Chorioretinal inflammation
0.716 0.284 0.000
J45.0 Predominantly allergic asthma
0.716 0.284 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.715 0.285 0.000
J02 Acute pharyngitis
0.712 0.288 0.000
Y42.5 Other oestrogens and progestogens
0.712 0.288 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.712 0.288 0.000
T66-T78 Other and unspecified effects of external causes
0.711 0.289 0.000
M10 Gout
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
J95-J99 Other diseases of the respiratory system
0.707 0.293 0.000
V10-V19 Pedal cyclist injured in transport accident
0.705 0.295 0.000
J69 Pneumonitis due to solids and liquids
0.705 0.295 0.000
L03.0 Cellulitis of finger and toe
0.704 0.296 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.704 0.296 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.704 0.296 0.000
E14.8 With unspecified complications
0.703 0.297 0.000
E14.7 With multiple complications
0.703 0.297 0.000
E14.5 With peripheral circulatory complications
0.703 0.297 0.000
E14.4 With neurological complications
0.703 0.297 0.000
E14.2 Withrenal complications
0.703 0.297 0.000
E14.1 With ketoacidosis
0.703 0.297 0.000
E14.0 With coma
0.703 0.297 0.000
J37 Chronic laryngitis and laryngotracheitis
0.703 0.297 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.698 0.302 0.000
Q60-Q64 Congenital malformations of the urinary system
0.698 0.302 0.000
E11.8 With unspecified complications
0.696 0.304 0.000
E11.7 With multiple complications
0.696 0.304 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.696 0.304 0.000
J00 Acute nasopharyngitis [common cold]
0.695 0.305 0.000
L30.9 Dermatitis, unspecified
0.694 0.306 0.000
J38.1 Polyp of vocal cord and larynx
0.693 0.306 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.693 0.306 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.691 0.309 0.000
E50-E64 Other nutritional deficiencies
0.690 0.310 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
Y00-Y09 Assault
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.689 0.311 0.000
X50-X57 Overexertion, travel and privation
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X20-X29 Contact with venomous animals and plants
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V40-V49 Car occupant injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
G56 Mononeuropathies of upper limb
0.688 0.312 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.687 0.313 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.687 0.313 0.000
H25.1 Senile nuclear cataract
0.684 0.316 0.000
H35.4 Peripheral retinal degeneration
0.683 0.317 0.000
E11.2 With renal complications
0.682 0.317 0.000
Y43 Primarily systemic agents
0.683 0.317 0.000
H33 Retinal detachments and breaks
0.682 0.318 0.000
E20-E35 Disorders of other endocrine glands
0.682 0.318 0.000
L29 Pruritus
0.680 0.320 0.000
S20-S29 Injuries to the thorax
0.679 0.321 0.000
G30-G32 Other degenerative diseases of the nervous system
0.679 0.321 0.000
T33-T35 Frostbite
0.678 0.322 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.678 0.322 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.678 0.322 0.000
T00-T07 Injuries involving multiple body regions
0.678 0.322 0.000
S10-S19 Injuries to the neck
0.678 0.322 0.000
S02 Fracture of skull and facial bones
0.678 0.322 0.000
Y59 Other and unspecified vaccines and biological substances
0.677 0.323 0.000
Y58 Bacterial vaccines
0.677 0.323 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.677 0.323 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.677 0.323 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.677 0.323 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.677 0.323 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.677 0.323 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
Y48 Anaesthetics and therapeutic gases
0.677 0.323 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.677 0.323 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.677 0.323 0.000
J33.1 Polypoid sinus degeneration
0.677 0.323 0.000
J32 Chronic sinusitis
0.677 0.323 0.000
L10-L14 Bullous disorders
0.676 0.324 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.676 0.324 0.000
H25.0 Senile incipient cataract
0.675 0.325 0.000
O47 False labour
0.674 0.326 0.000
Y44 Agents primarily affecting blood constituents
0.674 0.326 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.673 0.327 0.000
O85-O92 Complications predominantly related to the puerperium
0.673 0.327 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.672 0.328 0.000
S90-S99 Injuries to the ankle and foot
0.671 0.328 0.000
L05 Pilonidal cyst
0.671 0.329 0.000
J01 Acute sinusitis
0.669 0.331 0.000
M50-M54 Other dorsopathies
0.669 0.331 0.000
H26.3 Drug-induced cataract
0.668 0.332 0.000
H26.2 Complicated cataract
0.668 0.332 0.000
H26.1 Traumatic cataract
0.668 0.332 0.000
H26.0 Infantile, juvenile and presenile cataract
0.668 0.332 0.000
G57 Mononeuropathies of lower limb
0.667 0.333 0.000
M40-M43 Deforming dorsopathies
0.666 0.334 0.000
G54 Nerve root and plexus disorders
0.665 0.334 0.000
G96 Other disorders of central nervous system
0.665 0.335 0.000
M67.1 Other contracture of tendon (sheath)
0.665 0.335 0.000
F30-F39 Mood [affective] disorders
0.665 0.335 0.000
L28 Lichen simplex chronicus and prurigo
0.663 0.337 0.000
J06.9 Acute upper respiratory infection, unspecified
0.662 0.338 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.661 0.339 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.661 0.339 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.661 0.339 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.661 0.339 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.661 0.339 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.661 0.339 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.661 0.339 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.661 0.339 0.000
T36 Poisoning by systemic antibiotics
0.661 0.339 0.000
M88 Paget's disease of bone [osteitis deformans]
0.660 0.340 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.660 0.340 0.000
H35.8 Other specified retinal disorders
0.659 0.340 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.659 0.341 0.000
Y40.3 Macrolides
0.657 0.343 0.000
J34.2 Deviated nasal septum
0.657 0.343 0.000
L04 Acute lymphadenitis
0.656 0.344 0.000
L01 Impetigo
0.656 0.344 0.000
L00 Staphylococcal scalded skin syndrome
0.656 0.344 0.000
S06.5 Traumatic subdural haemorrhage
0.656 0.344 0.000
G20-G26 Extrapyramidal and movement disorders
0.653 0.347 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.653 0.347 0.000
L40-L45 Papulosquamous disorders
0.652 0.348 0.000
O36 Maternal care for other known or suspected foetal problems
0.652 0.348 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.651 0.349 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.649 0.350 0.000
M14.6 Neuropathic arthropathy
0.648 0.352 0.000
J35 Chronic diseases of tonsils and adenoids
0.648 0.352 0.000
M13.0 Polyarthritis, unspecified
0.647 0.352 0.000
Q80-Q89 Other congenital malformations
0.647 0.353 0.000
F60-F69 Disorders of adult personality and behaviour
0.647 0.353 0.000
Y40.0 Penicillins
0.646 0.354 0.000
V20-V29 Motorcycle rider injured in transport accident
0.646 0.354 0.000
T91 Sequelae of injuries of neck and trunk
0.646 0.354 0.000
F01.9 Vascular dementia, unspecified
0.644 0.356 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.644 0.356 0.000
J04 Acute laryngitis and tracheitis
0.643 0.357 0.000
U80 Agent resistant to penicillin and related antibiotics
0.643 0.357 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.641 0.359 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.641 0.359 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.639 0.360 0.000
S70-S79 Injuries to the hip and thigh
0.639 0.361 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.639 0.361 0.000
M45-M49 Spondylopathies
0.638 0.362 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.638 0.362 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.637 0.363 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.636 0.364 0.000
H43.8 Other disorders of vitreous body
0.635 0.365 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.635 0.365 0.000
L03.8 Cellulitis of other sites
0.634 0.366 0.000
O84 Multiple delivery
0.634 0.366 0.000
O83 Other assisted single delivery
0.634 0.366 0.000
O81 Single delivery by forceps and vacuum extractor
0.634 0.366 0.000
J39 Other diseases of upper respiratory tract
0.633 0.367 0.000
Q00-Q07 Congenital malformations of the nervous system
0.632 0.368 0.000
Chapter I Certain infectious and parasitic diseases
0.632 0.368 0.000
O48 Prolonged pregnancy
0.632 0.368 0.000
G90 Disorders of autonomic nervous system
0.631 0.369 0.000
J38.6 Stenosis of larynx
0.630 0.370 0.000
J38.5 Laryngeal spasm
0.630 0.370 0.000
J38.2 Nodules of vocal cords
0.630 0.370 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.628 0.372 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.628 0.372 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.628 0.372 0.000
Q50-Q56 Congenital malformations of genital organs
0.628 0.372 0.000
Q35-Q37 Cleft lip and cleft palate
0.628 0.372 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.628 0.372 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.628 0.372 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.628 0.372 0.000
F70-F79 Mental retardation
0.628 0.372 0.000
E15 Nondiabetic hypoglycaemic coma
0.627 0.373 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.627 0.373 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.626 0.374 0.000
F00 Dementia in Alzheimer's disease
0.626 0.374 0.000
L50-L54 Urticaria and erythema
0.625 0.375 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.623 0.376 0.000
O80.8 Other single spontaneous delivery
0.623 0.377 0.000
O80.1 Spontaneous breech delivery
0.623 0.377 0.000
X78 Intentional self-harm by sharp object
0.622 0.378 0.000
L03.3 Cellulitis of trunk
0.621 0.379 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.620 0.380 0.000
J38.0 Paralysis of vocal cords and larynx
0.618 0.381 0.000
T43.9 Psychotropic drug, unspecified
0.618 0.381 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.618 0.381 0.000
T43.6 Psychostimulants with abuse potential
0.618 0.381 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.618 0.381 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.618 0.381 0.000
Y46.4 Iminostilbenes
0.618 0.381 0.000
G52 Disorders of other cranial nerves
0.617 0.383 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.617 0.383 0.000
H35.9 Retinal disorder, unspecified
0.616 0.383 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.616 0.384 0.000
L08.1 Erythrasma
0.616 0.384 0.000
L08.0 Pyoderma
0.616 0.384 0.000
G80 Infantile cerebral palsy
0.616 0.384 0.000
M90 Osteopathies in diseases classified elsewhere
0.616 0.384 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.615 0.385 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.613 0.387 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.612 0.387 0.000
Y40.9 Systemic antibiotic, unspecified
0.611 0.389 0.000
J86 Pyothorax
0.611 0.389 0.000
J69.0 Pneumonitis due to food and vomit
0.611 0.389 0.000
H27.1 Dislocation of lens
0.610 0.389 0.000
G58 Other mononeuropathies
0.610 0.390 0.000
M86 Osteomyelitis
0.608 0.392 0.000
O44 Placenta praevia
0.608 0.392 0.000
F80-F89 Disorders of psychological development
0.608 0.392 0.000
H54.7 Unspecified visual loss
0.607 0.393 0.000
S05 Injury of eye and orbit
0.606 0.394 0.000
J03 Acute tonsillitis
0.605 0.395 0.000
O40 Polyhydramnios
0.605 0.395 0.000
L25 Unspecified contact dermatitis
0.605 0.395 0.000
L24 Irritant contact dermatitis
0.605 0.395 0.000
L23 Allergic contact dermatitis
0.605 0.395 0.000
L21 Seborrhoeic dermatitis
0.605 0.395 0.000
L20 Atopic dermatitis
0.605 0.395 0.000
L26 Exfoliative dermatitis
0.605 0.395 0.000
L22 Diaper [napkin] dermatitis
0.605 0.395 0.000
H20 Iridocyclitis
0.605 0.395 0.000
T42.4 Benzodiazepines
0.604 0.396 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.604 0.396 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.604 0.396 0.000
M66 Spontaneous rupture of synovium and tendon
0.604 0.396 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.603 0.397 0.000
H54.9 Unspecified visual impairment (binocular)
0.602 0.398 0.000
J36 Peritonsillar abscess
0.602 0.398 0.000
S31 Open wound of abdomen, lower back and pelvis
0.601 0.399 0.000
J11 Influenza, virus not identified
0.601 0.399 0.000
J70 Respiratory conditions due to other external agents
0.600 0.400 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.600 0.400 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.600 0.400 0.000
J66 Airway disease due to specific organic dust
0.600 0.400 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.600 0.400 0.000
J62 Pneumoconiosis due to dust containing silica
0.600 0.400 0.000
J65 Pneumoconiosis associated with tuberculosis
0.600 0.400 0.000
J64 Unspecified pneumoconiosis
0.600 0.400 0.000
J60 Coalworker's pneumoconiosis
0.600 0.400 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.599 0.401 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.599 0.401 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.598 0.401 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.598 0.402 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.598 0.402 0.000
O80.9 Single spontaneous delivery, unspecified
0.597 0.403 0.000
L60-L75 Disorders of skin appendages
0.597 0.403 0.000
J30.1 Allergic rhinitis due to pollen
0.596 0.404 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.595 0.405 0.000
F02 Dementia in other diseases classified elsewhere
0.595 0.405 0.000
F09 Unspecified organic or symptomatic mental disorder
0.595 0.405 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.595 0.405 0.000
O47.0 False labour before 37 completed weeks of gestation
0.594 0.406 0.000
M13.9 Arthritis, unspecified
0.594 0.406 0.000
T92 Sequelae of injuries of upper limb
0.594 0.406 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.593 0.407 0.000
Y40.8 Other systemic antibiotics
0.593 0.407 0.000
J47 Bronchiectasis
0.592 0.408 0.000
G71 Primary disorders of muscles
0.591 0.409 0.000
Y85 Sequelae of transport accidents
0.591 0.409 0.000
O30 Multiple gestation
0.590 0.410 0.000
F99-F99 Unspecified mental disorder
0.589 0.411 0.000
H35.7 Separation of retinal layers
0.589 0.411 0.000
H35.6 Retinal haemorrhage
0.589 0.411 0.000
H35.5 Hereditary retinal dystrophy
0.589 0.411 0.000
H35.2 Other proliferative retinopathy
0.589 0.411 0.000
H35.1 Retinopathy of prematurity
0.589 0.411 0.000
H35.0 Background retinopathy and retinal vascular changes
0.589 0.411 0.000
O45 Premature separation of placenta [abruptio placentae]
0.589 0.411 0.000
O43 Placental disorders
0.589 0.411 0.000
O41 Other disorders of amniotic fluid and membranes
0.589 0.411 0.000
O33 Maternal care for known or suspected disproportion
0.589 0.411 0.000
O31 Complications specific to multiple gestation
0.589 0.411 0.000
S60-S69 Injuries to the wrist and hand
0.589 0.411 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.589 0.411 0.000
M54 Dorsalgia
0.588 0.412 0.000
Y42.9 Other and unspecified hormone antagonists
0.587 0.412 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.587 0.412 0.000
Y42.4 Oral contraceptives
0.587 0.412 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.587 0.412 0.000
Y42.2 Antithyroid drugs
0.587 0.412 0.000
Y42.1 Thyroid hormones and substitutes
0.587 0.412 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.587 0.412 0.000
T50.8 Diagnostic agents
0.586 0.414 0.000
T50.7 Analeptics and opioid receptor antagonists
0.586 0.414 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.586 0.414 0.000
T50.5 Appetite depressants
0.586 0.414 0.000
T50.4 Drugs affecting uric acid metabolism
0.586 0.414 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.586 0.414 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.586 0.414 0.000
T50.1 Loop [high-ceiling] diuretics
0.586 0.414 0.000
T50.0 Mineralocorticoids and their antagonists
0.586 0.414 0.000
H60-H62 Diseases of external ear
0.585 0.415 0.000
G47 Sleep disorders
0.585 0.415 0.000
H54.0 Blindness, both eyes
0.584 0.416 0.000
T90 Sequelae of injuries of head
0.583 0.417 0.000
Y40.7 Antifungal antibiotics, systemically used
0.583 0.417 0.000
Y40.6 Rifamycins
0.583 0.417 0.000
Y40.5 Aminoglycosides
0.583 0.417 0.000
Y40.4 Tetracyclines
0.583 0.417 0.000
Y40.2 Chloramphenicol group
0.583 0.417 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.583 0.417 0.000
J02.9 Acute pharyngitis, unspecified
0.582 0.418 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.582 0.418 0.000
H10 Conjunctivitis
0.581 0.418 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.581 0.419 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.581 0.419 0.000
G93 Other disorders of brain
0.580 0.420 0.000
G82.5 Tetraplegia, unspecified
0.577 0.422 0.000
G82.4 Spastic tetraplegia
0.577 0.422 0.000
G82.3 Flaccid tetraplegia
0.577 0.422 0.000
G82.1 Spastic paraplegia
0.577 0.422 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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