TreeWAS – Variant ID: rs4632337

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter II Neoplasms	0.999	0.001
M50-M54 Other dorsopathies	0.998	0.002
M20-M25 Other joint disorders	0.997	0.003
Chapter IV Endocrine, nutritional and metabolic diseases	0.996	0.004
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.995	0.005
E70-E90 Metabolic disorders	0.994	0.006
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.992	0.008
Chapter XXI Factors influencing health status and contact with health services	0.991	0.009
Chapter X Diseases of the respiratory system	0.987	0.013
Chapter VI Diseases of the nervous system	0.987	0.013
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.986	0.014
J30-J39 Other diseases of upper respiratory tract	0.985	0.015
M54 Dorsalgia	0.985	0.015
E78.0 Pure hypercholesterolaemia	0.985	0.015
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.984	0.016
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.983	0.017
Chapter V Mental and behavioural disorders	0.979	0.021
R50-R69 General symptoms and signs	0.977	0.023
G50-G59 Nerve, nerve root and plexus disorders	0.976	0.024
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.975	0.025
R63 Symptoms and signs concerning food and fluid intake	0.971	0.029
M31 Other necrotising vasculopathies	0.971	0.029
M54.5 Low back pain	0.971	0.029
D37-D48 Neoplasms of uncertain or unknown behaviour	0.965	0.035
M45-M49 Spondylopathies	0.965	0.035
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.963	0.037
Chapter VII Diseases of the eye and adnexa	0.963	0.037
M15-M19 Arthrosis	0.962	0.038
Chapter IX Diseases of the circulatory system	0.958	0.042
J34 Other disorders of nose and nasal sinuses	0.955	0.045
M31.6 Other giant cell arteritis	0.952	0.048
R63.4 Abnormal weight loss	0.952	0.048
Z40-Z54 Persons encountering health services for specific procedures and health care	0.952	0.048
Chapter I Certain infectious and parasitic diseases	0.952	0.048
R55 Syncope and collapse	0.951	0.049
M19 Other arthrosis	0.947	0.053
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.946	0.054
M25 Other joint disorders, not elsewhere classified	0.941	0.059
I20-I25 Ischaemic heart diseases	0.937	0.063
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.937	0.063
J34.3 Hypertrophy of nasal turbinates	0.927	0.073
M19.9 Arthrosis, unspecified	0.927	0.073
J32 Chronic sinusitis	0.926	0.074
Z98 Other postsurgical states	0.924	0.076
M50 Cervical disk disorders	0.923	0.077
M47 Spondylosis	0.918	0.082
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.917	0.083
M54.59 Low back pain (Site unspecified)	0.915	0.085
C77.0 Lymph nodes of head, face and neck	0.913	0.087
Z80 Family history of malignant neoplasm	0.911	0.089
E78.5 Hyperlipidaemia, unspecified	0.909	0.091
D45 Polycythaemia vera	0.905	0.095
C79 Secondary malignant neoplasm of other sites	0.902	0.098
I70-I79 Diseases of arteries, arterioles and capillaries	0.900	0.100
M51 Other intervertebral disk disorders	0.897	0.103
I24 Other acute ischaemic heart diseases	0.895	0.105
R63.0 Anorexia	0.890	0.110
Z40 Prophylactic surgery	0.885	0.115
C15-C26 Malignant neoplasms of digestive organs	0.884	0.116
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.883	0.117
C77.1 Intrathoracic lymph nodes	0.882	0.118
M47.8 Other spondylosis	0.875	0.125
Z88.5 Personal history of allergy to narcotic agent	0.873	0.127
Z43 Attention to artificial openings	0.870	0.130
Z51 Other medical care	0.870	0.130
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.866	0.134
M50.1 Cervical disk disorder with radiculopathy	0.866	0.134
H53-H54 Visual disturbances and blindness	0.866	0.134
M05-M14 Inflammatory polyarthropathies	0.866	0.134
M22 Disorders of patella	0.864	0.136
F30-F39 Mood [affective] disorders	0.864	0.136
F00-F09 Organic, including symptomatic, mental disorders	0.858	0.142
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.858	0.142
B95-B98 Bacterial, viral and other infectious agents	0.858	0.142
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.856	0.144
R60 Oedema, not elsewhere classified	0.856	0.144
Z98.0 Intestinal bypass and anastomosis status	0.851	0.149
I21 Acute myocardial infarction	0.851	0.149
Z95 Presence of cardiac and vascular implants and grafts	0.850	0.150
D00-D09 In situ neoplasms	0.849	0.151
J34.2 Deviated nasal septum	0.848	0.152
G58 Other mononeuropathies	0.845	0.155
M19.99 Arthrosis, unspecified (Site unspecified)	0.845	0.155
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.843	0.157
R69 Unknown and unspecified causes of morbidity	0.841	0.159
M51.2 Other specified intervertebral disk displacement	0.841	0.159
M54.57 Low back pain (Lumbosacral region)	0.840	0.160
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.840	0.160
J32.9 Chronic sinusitis, unspecified	0.839	0.161
M19.98 Arthrosis, unspecified (Other)	0.838	0.162
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.838	0.162
M17 Gonarthrosis [arthrosis of knee]	0.836	0.164
J33 Nasal polyp	0.832	0.168
E83 Disorders of mineral metabolism	0.829	0.171
Z98.1 Arthrodesis status	0.829	0.171
I05-I09 Chronic rheumatic heart diseases	0.829	0.171
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.827	0.173
M54.56 Low back pain (Lumbar region)	0.826	0.174
M47.82 Other spondylosis (Cervical region)	0.824	0.176
Z45 Adjustment and management of implanted device	0.822	0.178
H43-H45 Disorders of vitreous body and globe	0.822	0.178
Z51.1 Chemotherapy session for neoplasm	0.820	0.180
G90-G99 Other disorders of the nervous system	0.817	0.182
I24.8 Other forms of acute ischaemic heart disease	0.816	0.184
B35-B49 Mycoses	0.813	0.187
M70-M79 Other soft tissue disorders	0.813	0.187
H10-H13 Disorders of conjunctiva	0.811	0.189
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.809	0.191
I74 Arterial embolism and thrombosis	0.809	0.191
M25.4 Effusion of joint	0.804	0.196
G50 Disorders of trigeminal nerve	0.804	0.196
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.803	0.197
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.796	0.204
H30-H36 Disorders of choroid and retina	0.795	0.205
Z81 Family history of mental and behavioural disorders	0.794	0.206
E78.8 Other disorders of lipoprotein metabolism	0.793	0.207
G20-G26 Extrapyramidal and movement disorders	0.792	0.208
Z88.0 Personal history of allergy to penicillin	0.791	0.209
Chapter XXII Codes for special purposes	0.790	0.210
H55-H59 Other disorders of eye and adnexa	0.790	0.210
F40-F48 Neurotic, stress-related and somatoform disorders	0.790	0.210
M17.1 Other primary gonarthrosis	0.790	0.210
E00-E07 Disorders of thyroid gland	0.790	0.210
Z80.0 Family history of malignant neoplasm of digestive organs	0.789	0.211
C34 Malignant neoplasm of bronchus and lung	0.789	0.211
R53 Malaise and fatigue	0.788	0.212
F31 Bipolar affective disorder	0.788	0.212
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.787	0.213
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.787	0.213
J80-J84 Other respiratory diseases principally affecting the interstitium	0.786	0.214
M21 Other acquired deformities of limbs	0.786	0.214
B25-B34 Other viral diseases	0.786	0.214
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.781	0.219
M13 Other arthritis	0.781	0.219
I21.9 Acute myocardial infarction, unspecified	0.781	0.219
I24.9 Acute ischaemic heart disease, unspecified	0.780	0.220
G54 Nerve root and plexus disorders	0.777	0.223
D05 Carcinoma in situ of breast	0.777	0.223
H53 Visual disturbances	0.777	0.223
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.775	0.225
R58 Haemorrhage, not elsewhere classified	0.774	0.226
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.773	0.227
Z95.8 Presence of other cardiac and vascular implants and grafts	0.772	0.228
C19 Malignant neoplasm of rectosigmoid junction	0.770	0.230
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.769	0.231
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.769	0.231
M19.96 Arthrosis, unspecified-Lower leg	0.768	0.232
C64-C68 Malignant neoplasms of urinary tract	0.768	0.232
F29 Unspecified nonorganic psychosis	0.768	0.232
C79.2 Secondary malignant neoplasm of skin	0.767	0.233
M54.2 Cervicalgia	0.767	0.233
Z51.3 Blood transfusion without reported diagnosis	0.766	0.234
J39 Other diseases of upper respiratory tract	0.765	0.235
Z43.2 Attention to ileostomy	0.765	0.235
G51 Facial nerve disorders	0.765	0.235
R63.8 Other symptoms and signs concerning food and fluid intake	0.764	0.235
C78.7 Secondary malignant neoplasm of liver	0.764	0.236
M79 Other soft tissue disorders, not elsewhere classified	0.764	0.236
I71 Aortic aneurysm and dissection	0.764	0.236
I21.1 Acute transmural myocardial infarction of inferior wall	0.763	0.237
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.762	0.238
M48 Other spondylopathies	0.762	0.238
M46 Other inflammatory spondylopathies	0.759	0.241
M19.1 Posttraumatic arthrosis of other joints	0.758	0.242
E89.0 Postprocedural hypothyroidism	0.758	0.242
J32.8 Other chronic sinusitis	0.758	0.242
R47-R49 Symptoms and signs involving speech and voice	0.757	0.243
M25.7 Osteophyte	0.757	0.243
Z48 Other surgical follow-up care	0.755	0.245
C78.0 Secondary malignant neoplasm of lung	0.754	0.246
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.752	0.248
Chapter XX External causes of morbidity and mortality	0.752	0.248
Z45.2 Adjustment and management of vascular access device	0.750	0.250
G30-G32 Other degenerative diseases of the nervous system	0.749	0.251
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.748	0.252
M86-M90 Other osteopathies	0.748	0.252
I77 Other disorders of arteries and arterioles	0.746	0.254
M54.50 Low back pain (Multiple sites in spine)	0.745	0.255
J36 Peritonsillar abscess	0.744	0.256
M34 Systemic sclerosis	0.744	0.256
M25.5 Pain in joint	0.744	0.256
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.743	0.257
M25.8 Other specified joint disorders	0.742	0.258
M54.3 Sciatica	0.742	0.258
G70-G73 Diseases of myoneural junction and muscle	0.741	0.259
H53.0 Amblyopia ex anopsia	0.741	0.259
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.740	0.260
M19.97 Arthrosis, unspecified (Ankle and foot)	0.739	0.261
M50.3 Other cervical disk degeneration	0.739	0.261
I95-I99 Other and unspecified disorders of the circulatory system	0.739	0.261
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.738	0.262
F03 Unspecified dementia	0.738	0.262
F80-F89 Disorders of psychological development	0.737	0.263
M23 Internal derangement of knee	0.736	0.264
J60-J70 Lung diseases due to external agents	0.736	0.264
C77.3 Axillary and upper limb lymph nodes	0.734	0.265
R52 Pain, not elsewhere classified	0.734	0.266
M25.6 Stiffness of joint, not elsewhere classified	0.734	0.266
M22.4 Chondromalacia patellae	0.734	0.266
I22 Subsequent myocardial infarction	0.734	0.266
G58.8 Other specified mononeuropathies	0.733	0.267
M19.0 Primary arthrosis of other joints	0.732	0.268
C79.7 Secondary malignant neoplasm of adrenal gland	0.732	0.268
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.731	0.269
C49 Malignant neoplasm of other connective and soft tissue	0.731	0.269
I08 Multiple valve diseases	0.730	0.270
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.729	0.271
B15-B19 Viral hepatitis	0.729	0.271
M54.9 Dorsalgia, unspecified	0.728	0.271
M20 Acquired deformities of fingers and toes	0.728	0.272
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.727	0.272
J20-J22 Other acute lower respiratory infections	0.726	0.274
M54.1 Radiculopathy	0.725	0.275
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.725	0.275
J32.0 Chronic maxillary sinusitis	0.725	0.275
E50-E64 Other nutritional deficiencies	0.724	0.276
M91-M94 Chondropathies	0.723	0.277
C80 Malignant neoplasm without specification of site	0.723	0.277
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.723	0.277
J38.3 Other diseases of vocal cords	0.723	0.277
E87 Other disorders of fluid, electrolyte and acid-base balance	0.722	0.278
C20 Malignant neoplasm of rectum	0.721	0.279
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.721	0.279
H43 Disorders of vitreous body	0.720	0.280
M13.9 Arthritis, unspecified	0.720	0.280
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.720	0.280
C77.8 Lymph nodes of multiple regions	0.717	0.282
E20-E35 Disorders of other endocrine glands	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C51-C58 Malignant neoplasms of female genital organs	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.716	0.284
M53 Other dorsopathies, not elsewhere classified	0.716	0.284
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285
M33 Dermatopolymyositis	0.715	0.285
M32 Systemic lupus erythematosus	0.715	0.285
M30 Polyarteritis nodosa and related conditions	0.715	0.285
M40-M43 Deforming dorsopathies	0.714	0.285
E40-E46 Malnutrition	0.714	0.286
C76 Malignant neoplasm of other and ill-defined sites	0.714	0.286
M47.87 Other spondylosis (Lumbosacral region)	0.714	0.286
Z80.4 Family history of malignant neoplasm of genital organs	0.713	0.287
Z89 Acquired absence of limb	0.713	0.287
E88 Other metabolic disorders	0.713	0.287
E85 Amyloidosis	0.713	0.287
E84 Cystic fibrosis	0.713	0.287
E79 Disorders of purine and pyrimidine metabolism	0.713	0.287
E77 Disorders of glycoprotein metabolism	0.713	0.287
E76 Disorders of glycosaminoglycan metabolism	0.713	0.287
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.713	0.287
E74 Other disorders of carbohydrate metabolism	0.713	0.287
E73 Lactose intolerance	0.713	0.287
E72 Other disorders of amino-acid metabolism	0.713	0.287
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.713	0.287
E70 Disorders of aromatic amino-acid metabolism	0.713	0.287
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.713	0.287
C78.2 Secondary malignant neoplasm of pleura	0.712	0.288
C34.3 Lower lobe, bronchus or lung	0.712	0.288
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.712	0.288
Z43.5 Attention to cyctostomy	0.712	0.288
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.712	0.288
E78.9 Disorder of lipoprotein metabolism, unspecified	0.711	0.289
E78.6 Lipoprotein deficiency	0.711	0.289
E78.4 Other hyperlipidaemia	0.711	0.289
E78.3 Hyperchylomicronaemia	0.711	0.289
E78.2 Mixed hyperlipidaemia	0.711	0.289
E78.1 Pure hyperglyceridaemia	0.711	0.289
J09-J18 Influenza and pneumonia	0.711	0.289
R60.0 Localised oedema	0.711	0.289
M47.9 Spondylosis, unspecified	0.710	0.290
Z80.9 Family history of malignant neoplasm, unspecified	0.709	0.291
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.708	0.292
Z95.0 Presence of cardiac pacemaker	0.708	0.292
G00-G09 Inflammatory diseases of the central nervous system	0.707	0.292
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.707	0.293
Z84 Family history of other conditions	0.707	0.293
M19.92 Arthrosis, unspecified (Upper arm)	0.707	0.293
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.706	0.293
J37 Chronic laryngitis and laryngotracheitis	0.706	0.293
M54.8 Other dorsalgia	0.706	0.294
M54.6 Pain in thoracic spine	0.706	0.294
M54.0 Panniculitis affecting regions of neck and back	0.706	0.294
M45 Ankylosing spondylitis	0.706	0.294
Z86 Personal history of certain other diseases	0.706	0.294
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.706	0.294
Z88.7 Personal history of allergy to serum and vaccine	0.706	0.294
Z88.2 Personal history of allergy to sulphonamides	0.705	0.295
Z51.5 Palliative care	0.705	0.295
Z97 Presence of other devices	0.703	0.297
F99-F99 Unspecified mental disorder	0.702	0.298
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.702	0.298
F70-F79 Mental retardation	0.702	0.298
F60-F69 Disorders of adult personality and behaviour	0.702	0.298
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.702	0.298
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.701	0.299
D70-D77 Other diseases of blood and blood-forming organs	0.701	0.299
C79.9 Secondary malignant neoplasm, unspecified site	0.700	0.299
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.700	0.300
R62 Lack of expected normal physiological development	0.700	0.300
R57 Shock, not elsewhere classified	0.700	0.300
R64 Cachexia	0.700	0.300
C79.8 Secondary malignant neoplasm of other specified sites	0.700	0.300
G59 Mononeuropathy in diseases classified elsewhere	0.700	0.300
G53 Cranial nerve disorders in diseases classified elsewhere	0.700	0.300
G52 Disorders of other cranial nerves	0.700	0.300
R95-R99 Ill-defined and unknown causes of mortality	0.699	0.301
M25.47 Effusion of joint (Ankle and foot)	0.699	0.301
D46 Myelodysplastic syndromes	0.699	0.301
F05 Delirium, not induced by alcohol and other psychoactive substances	0.699	0.301
R60.1 Generalised oedema	0.697	0.303
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.697	0.303
R63.6 Insufficient intake of food and water due to self neglect	0.696	0.304
R63.5 Abnormal weight gain	0.696	0.304
R63.3 Feeding difficulties and mismanagement	0.696	0.304
R63.2 Polyphagia	0.696	0.304
R63.1 Polydipsia	0.696	0.304
M31.9 Necrotising vasculopathy, unspecified	0.696	0.304
M31.8 Other specified necrotising vasculopathies	0.696	0.304
M31.7 Microscopic polyangiitis	0.696	0.304
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.696	0.304
M31.4 Aortic arch syndrome [Takayasu]	0.696	0.304
M31.3 Wegener's granulomatosis	0.696	0.304
M31.2 Lethal midline granuloma	0.696	0.304
M31.1 Thrombotic microangiopathy	0.696	0.304
M31.0 Hypersensitivity angiitis	0.696	0.304
M54.55 Low back pain (Thoracolumbar region)	0.696	0.304
M54.54 Low back pain-Thoracic	0.696	0.304
M54.53 Low back pain-Cervicothoracic	0.696	0.304
M54.52 Low back pain-Cervical	0.696	0.304
M54.51 Low back pain-Occipit-atl-axl	0.696	0.304
R20 Disturbances of skin sensation	0.696	0.304
M17.0 Primary gonarthrosis, bilateral	0.696	0.304
Z99.3 Dependence on wheelchair	0.695	0.305
J38.4 Oedema of larynx	0.695	0.305
M47.89 Other spondylosis (Site unspecified)	0.694	0.306
C77.4 Inguinal and lower limb lymph nodes	0.694	0.306
M80-M85 Disorders of bone density and structure	0.693	0.307
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.693	0.307
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.692	0.308
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.692	0.308
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.692	0.308
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.692	0.308
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.692	0.308
I08.1 Disorders of both mitral and tricuspid valves	0.692	0.308
M49 Spondylopathies in diseases classified elsewhere	0.692	0.308
H46-H48 Disorders of optic nerve and visual pathways	0.691	0.309
M15 Polyarthrosis	0.690	0.310
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.690	0.310
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.689	0.311
M19.91 Arthrosis, unspecified (Shoulder region)	0.689	0.311
G57 Mononeuropathies of lower limb	0.689	0.311
J95-J99 Other diseases of the respiratory system	0.688	0.312
I00-I02 Acute rheumatic fever	0.687	0.313
I70 Atherosclerosis	0.686	0.313
F33 Recurrent depressive disorder	0.686	0.314
B37 Candidiasis	0.686	0.314
E83.5 Disorders of calcium metabolism	0.685	0.315
J33.8 Other polyp of sinus	0.685	0.315
J34.1 Cyst and mucocele of nose and nasal sinus	0.685	0.315
J34.0 Abscess, furuncle and carbuncle of nose	0.685	0.315
I20 Angina pectoris	0.685	0.315
Z88.4 Personal history of allergy to anaesthetic agent	0.684	0.316
M20.2 Hallux rigidus	0.683	0.317
Z54 Convalescence	0.682	0.317
Z49 Care involving dialysis	0.682	0.317
Z44 Fitting and adjustment of external prosthetic device	0.682	0.317
B99-B99 Other infectious diseases	0.682	0.318
B90-B94 Sequelae of infectious and parasitic diseases	0.682	0.318
B85-B89 Pediculosis, acariasis and other infestations	0.682	0.318
B65-B83 Helminthiases	0.682	0.318
B50-B64 Protozoal diseases	0.682	0.318
B20-B24 Human immunodeficiency virus [HIV] disease	0.682	0.318
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.682	0.318
A80-A89 Viral infections of the central nervous system	0.682	0.318
A75-A79 Rickettsioses	0.682	0.318
A70-A74 Other diseases caused by chlamydiae	0.682	0.318
A65-A69 Other spirochaetal diseases	0.682	0.318
A50-A64 Infections with a predominantly sexual mode of transmission	0.682	0.318
A20-A28 Certain zoonotic bacterial diseases	0.682	0.318
A15-A19 Tuberculosis	0.682	0.318
J33.0 Polyp of nasal cavity	0.682	0.318
R50 Fever of unknown origin	0.681	0.319
C21 Malignant neoplasm of anus and anal canal	0.680	0.319
G50.0 Trigeminal neuralgia	0.680	0.320
Z43.3 Attention to colostomy	0.680	0.320
M19.8 Other specified arthrosis	0.679	0.321
M19.2 Other secondary arthrosis	0.679	0.321
Z51.8 Other specified medical care	0.678	0.321
M25.77 Osteophyte (Ankle and foot)	0.678	0.322
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.678	0.322
G55.0 Nerve root and plexus compressions in neoplastic disease	0.678	0.322
M24 Other specific joint derangements	0.677	0.323
B97 Viral agents as the cause of diseases classified to other chapters	0.677	0.323
E16 Other disorders of pancreatic internal secretion	0.675	0.324
Z93 Artificial opening status	0.675	0.325
Z95.1 Presence of aortocoronary bypass graft	0.675	0.325
H40-H42 Glaucoma	0.675	0.325
M25.9 Joint disorder, unspecified	0.674	0.325
M25.3 Other instability of joint	0.674	0.325
M25.2 Flail joint	0.674	0.325
M25.1 Fistula of joint	0.674	0.325
M25.0 Haemarthrosis	0.674	0.325
M22.8 Other disorders of patella	0.674	0.326
H54 Blindness and low vision	0.673	0.326
D37.5 Rectum	0.673	0.327
F41 Other anxiety disorders	0.673	0.327
R68 Other general symptoms and signs	0.672	0.328
I23 Certain current complications following acute myocardial infarction	0.672	0.328
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.671	0.329
M19.94 Arthrosis, unspecified (Hand)	0.670	0.330
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.669	0.331
H11 Other disorders of conjunctiva	0.669	0.331
C25 Malignant neoplasm of pancreas	0.668	0.332
Z85 Personal history of malignant neoplasm	0.667	0.333
M35 Other systemic involvement of connective tissue	0.667	0.333
B34 Viral infection of unspecified site	0.667	0.333
H57 Other disorders of eye and adnexa	0.666	0.334
J84 Other interstitial pulmonary diseases	0.666	0.334
M54.4 Lumbago with sciatica	0.666	0.334
H34 Retinal vascular occlusions	0.666	0.334
C18 Malignant neoplasm of colon	0.666	0.334
M79.8 Other specified soft tissue disorders	0.665	0.335
G93 Other disorders of brain	0.665	0.335
Z86.6 Personal history of diseases of the nervous system and sense organs	0.665	0.335
J32.4 Chronic pansinusitis	0.664	0.336
J32.3 Chronic sphenoidal sinusitis	0.664	0.336
J32.2 Chronic ethmoidal sinusitis	0.664	0.336
J32.1 Chronic frontal sinusitis	0.664	0.336
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.664	0.336
Z80.8 Family history of malignant neoplasm of other organs or systems	0.663	0.337
F31.9 Bipolar affective disorder, unspecified	0.663	0.337
Z98.2 Presence of cerebrospinal fluid drainage device	0.662	0.337
Z95.5 Presence of coronary angioplasty implant and graft	0.662	0.338
M50.9 Cervical disk disorder, unspecified	0.662	0.338
M50.8 Other cervical disk disorders	0.662	0.338
C32 Malignant neoplasm of larynx	0.661	0.338
R22.0 Localised swelling, mass and lump, head	0.661	0.339
G80-G83 Cerebral palsy and other paralytic syndromes	0.661	0.339
Z52 Donors of organs and tissues	0.661	0.339
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.660	0.340
C77.2 Intra-abdominal lymph nodes	0.660	0.340
D05.1 Intraductal carcinoma in situ	0.659	0.341
M47.80 Other spondylosis (Multiple sites in spine)	0.659	0.341
M47.2 Other spondylosis with radiculopathy	0.658	0.342
M47.1 Other spondylosis with myelopathy	0.658	0.342
M47.0 Anterior spinal and vertebral artery compression syndromes	0.658	0.342
C78.4 Secondary malignant neoplasm of small intestine	0.658	0.342
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.658	0.342
C78.1 Secondary malignant neoplasm of mediastinum	0.658	0.342
Z81.8 Family history of other mental and behavioural disorders	0.656	0.344
I74.5 Embolism and thrombosis of iliac artery	0.656	0.344
E87.5 Hyperkalaemia	0.655	0.345
C34.1 Upper lobe, bronchus or lung	0.654	0.346
Z48.9 Surgical follow-up care, unspecified	0.654	0.346
A30-A49 Other bacterial diseases	0.654	0.346
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.653	0.347
Z80.6 Family history of leukaemia	0.653	0.347
Z80.5 Family history of malignant neoplasm of urinary tract	0.653	0.347
E80 Disorders of porphyrin and bilirubin metabolism	0.652	0.348
M07 Psoriatic and enteropathic arthropathies	0.652	0.348
Z94 Transplanted organ and tissue status	0.651	0.349
H35 Other retinal disorders	0.651	0.349
G20 Parkinson's disease	0.651	0.349
D04 Carcinoma in situ of skin	0.650	0.349
G95 Other diseases of spinal cord	0.650	0.350
Z99.8 Dependence on other enabling machines and devices	0.649	0.350
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.649	0.351
E07 Other disorders of thyroid	0.647	0.353
C79.6 Secondary malignant neoplasm of ovary	0.647	0.353
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.647	0.353
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.647	0.353
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.647	0.353
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.646	0.354
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.645	0.355
I72 Other aneurysm	0.645	0.355
J35 Chronic diseases of tonsils and adenoids	0.645	0.355
D05.9 Carcinoma in situ of breast, unspecified	0.644	0.356
G58.9 Mononeuropathy, unspecified	0.643	0.356
M51.3 Other specified intervertebral disk degeneration	0.643	0.357
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.643	0.357
M51.9 Intervertebral disk disorder, unspecified	0.643	0.357
M51.8 Other specified intervertebral disk disorders	0.643	0.357
M51.4 Schmorl's nodes	0.643	0.357
I24.1 Dressler's syndrome	0.642	0.358
J38.7 Other diseases of larynx	0.640	0.360
J38.1 Polyp of vocal cord and larynx	0.640	0.360
M05 Seropositive rheumatoid arthritis	0.639	0.361
R54 Senility	0.639	0.361
M11 Other crystal arthropathies	0.638	0.362
F41.9 Anxiety disorder, unspecified	0.637	0.363
M77 Other enthesopathies	0.637	0.363
R22.9 Localised swelling, mass and lump, unspecified	0.637	0.363
M54.29 Cervicalgia-Site unspe	0.636	0.363
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.636	0.363
M50.2 Other cervical disk displacement	0.636	0.364

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations