TreeWAS – Variant ID: rs4750535

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
# Top node	0.837	0.163
Chapter IX Diseases of the circulatory system	0.849	0.151
Chapter XXI Factors influencing health status and contact with health services	0.853	0.147
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.854	0.146
Chapter VIII Diseases of the ear and mastoid process	0.860	0.140
Chapter VI Diseases of the nervous system	0.861	0.139
Chapter X Diseases of the respiratory system	0.862	0.138
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.863	0.137
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.864	0.136
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.864	0.136
I30-I52 Other forms of heart disease	0.871	0.129
Chapter XX External causes of morbidity and mortality	0.871	0.129
Chapter I Certain infectious and parasitic diseases	0.872	0.128
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.874	0.126
Z40-Z54 Persons encountering health services for specific procedures and health care	0.877	0.123
I20-I25 Ischaemic heart diseases	0.879	0.121
Z86 Personal history of certain other diseases	0.880	0.120
Chapter V Mental and behavioural disorders	0.881	0.119
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.882	0.118
Chapter XVI Certain conditions originating in the perinatal period	0.883	0.117
Chapter IV Endocrine, nutritional and metabolic diseases	0.884	0.116
Chapter XXII Codes for special purposes	0.884	0.116
Chapter VII Diseases of the eye and adnexa	0.884	0.116
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.884	0.116
Chapter XII Diseases of the skin and subcutaneous tissue	0.885	0.115
Chapter II Neoplasms	0.885	0.115
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.886	0.114
I10-I15 Hypertensive diseases	0.886	0.114
H90-H95 Other disorders of ear	0.886	0.114
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.886	0.114
S20-S29 Injuries to the thorax	0.887	0.113
J40-J47 Chronic lower respiratory diseases	0.889	0.111
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.889	0.111
H65-H75 Diseases of middle ear and mastoid	0.889	0.110
Chapter XI Diseases of the digestive system	0.890	0.110
S00-S09 Injuries to the head	0.890	0.110
G90-G99 Other disorders of the nervous system	0.890	0.109
I95-I99 Other and unspecified disorders of the circulatory system	0.891	0.109
T15-T19 Effects of foreign body entering through natural orifice	0.891	0.109
S60-S69 Injuries to the wrist and hand	0.891	0.108
S70-S79 Injuries to the hip and thigh	0.892	0.108
I00-I02 Acute rheumatic fever	0.892	0.108
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.892	0.108
S40-S49 Injuries to the shoulder and upper arm	0.892	0.107
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.892	0.107
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.893	0.107
I05-I09 Chronic rheumatic heart diseases	0.893	0.107
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.893	0.107
S10-S19 Injuries to the neck	0.893	0.106
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.894	0.106
T66-T78 Other and unspecified effects of external causes	0.894	0.106
G00-G09 Inflammatory diseases of the central nervous system	0.894	0.106
J09-J18 Influenza and pneumonia	0.894	0.106
I60-I69 Cerebrovascular diseases	0.894	0.106
Z92 Personal history of medical treatment	0.894	0.106
G70-G73 Diseases of myoneural junction and muscle	0.894	0.105
S90-S99 Injuries to the ankle and foot	0.895	0.105
I70-I79 Diseases of arteries, arterioles and capillaries	0.895	0.105
M05-M14 Inflammatory polyarthropathies	0.895	0.105
T33-T35 Frostbite	0.895	0.105
T26-T28 Burns and corrosions confined to eye and internal organs	0.895	0.105
G80-G83 Cerebral palsy and other paralytic syndromes	0.895	0.105
G40-G47 Episodic and paroxysmal disorders	0.895	0.105
Z85 Personal history of malignant neoplasm	0.895	0.105
T00-T07 Injuries involving multiple body regions	0.895	0.105
S80-S89 Injuries to the knee and lower leg	0.895	0.104
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.895	0.104
T79-T79 Certain early complications of trauma	0.895	0.104
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.896	0.104
T20-T25 Burns and corrosions of external body surface, specified by site	0.896	0.104
M70-M79 Other soft tissue disorders	0.896	0.104
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.896	0.104
H60-H62 Diseases of external ear	0.896	0.104
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.896	0.104
H80-H83 Diseases of inner ear	0.896	0.104
J80-J84 Other respiratory diseases principally affecting the interstitium	0.896	0.104
Z90 Acquired absence of organs, not elsewhere classified	0.897	0.103
M80-M85 Disorders of bone density and structure	0.897	0.103
S50-S59 Injuries to the elbow and forearm	0.897	0.103
M20-M25 Other joint disorders	0.897	0.103
M65-M68 Disorders of synovium and tendon	0.897	0.103
Z70-Z76 Persons encountering health services in other circumstances	0.897	0.102
T36-T50 Poisoning by drugs, medicaments and biological substances	0.897	0.102
Z87 Personal history of other diseases and conditions	0.898	0.102
Z80 Family history of malignant neoplasm	0.898	0.102
J20-J22 Other acute lower respiratory infections	0.898	0.102
J95-J99 Other diseases of the respiratory system	0.899	0.101
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.899	0.101
M50-M54 Other dorsopathies	0.899	0.101
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.899	0.100
M86-M90 Other osteopathies	0.899	0.100
M40-M43 Deforming dorsopathies	0.900	0.100
G35-G37 Demyelinating diseases of the central nervous system	0.900	0.100
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.900	0.100
I84 Haemorrhoids	0.900	0.100
Z94 Transplanted organ and tissue status	0.900	0.100
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.900	0.100
J30-J39 Other diseases of upper respiratory tract	0.900	0.099
Z00-Z13 Persons encountering health services for examination and investigation	0.901	0.099
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.901	0.099
J00-J06 Acute upper respiratory infections	0.901	0.099
Z95 Presence of cardiac and vascular implants and grafts	0.901	0.099
G30-G32 Other degenerative diseases of the nervous system	0.901	0.099
I50 Heart failure	0.901	0.099
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.901	0.099
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.901	0.099
Z51 Other medical care	0.901	0.099
J60-J70 Lung diseases due to external agents	0.901	0.098
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.902	0.098
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.902	0.098
M00-M03 Infectious arthropathies	0.902	0.098
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.902	0.098
Z96 Presence of other functional implants	0.902	0.098
M60-M63 Disorders of muscles	0.902	0.098
G20-G26 Extrapyramidal and movement disorders	0.902	0.098
M91-M94 Chondropathies	0.902	0.098
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.902	0.098
Z81 Family history of mental and behavioural disorders	0.902	0.098
I44 Atrioventricular and left bundle-branch block	0.902	0.098
Z84 Family history of other conditions	0.902	0.098
Chapter XIV Diseases of the genitourinary system	0.902	0.098
Z86.4 Personal history of psychoactive substance abuse	0.902	0.098
R95-R99 Ill-defined and unknown causes of mortality	0.902	0.098
I51 Complications and ill-defined descriptions of heart disease	0.902	0.098
Z89 Acquired absence of limb	0.902	0.097
I46 Cardiac arrest	0.903	0.097
W00-W19 Falls	0.903	0.097
Z97 Presence of other devices	0.903	0.097
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.903	0.097
M15-M19 Arthrosis	0.903	0.097
A30-A49 Other bacterial diseases	0.903	0.097
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.903	0.097
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.903	0.097
A00-A09 Intestinal infectious diseases	0.903	0.097
J90-J94 Other diseases of pleura	0.903	0.097
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.903	0.097
I45 Other conduction disorders	0.903	0.096
I25 Chronic ischaemic heart disease	0.904	0.096
R47-R49 Symptoms and signs involving speech and voice	0.904	0.096
G50-G59 Nerve, nerve root and plexus disorders	0.904	0.096
Z83 Family history of other specific disorders	0.904	0.096
Z91 Personal history of risk-factors, not elsewhere classified	0.904	0.096
I35 Nonrheumatic aortic valve disorders	0.904	0.096
B15-B19 Viral hepatitis	0.904	0.095
I80 Phlebitis and thrombophlebitis	0.905	0.095
Z93 Artificial opening status	0.905	0.095
Z98 Other postsurgical states	0.905	0.095
I30 Acute pericarditis	0.905	0.095
R50-R69 General symptoms and signs	0.905	0.095
R07 Pain in throat and chest	0.905	0.095
M45-M49 Spondylopathies	0.905	0.094
V90-V94 Water transport accidents	0.905	0.094
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.906	0.094
B35-B49 Mycoses	0.906	0.094
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.906	0.094
I42 Cardiomyopathy	0.906	0.094
Z86.0 Personal history of other neoplasms	0.906	0.094
W20-W49 Exposure to inanimate mechanical forces	0.906	0.093
Z86.6 Personal history of diseases of the nervous system and sense organs	0.906	0.093
I49 Other cardiac arrhythmias	0.907	0.093
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.907	0.093
T81 Complications of procedures, not elsewhere classified	0.907	0.093
I82 Other venous embolism and thrombosis	0.907	0.093
I87 Other disorders of veins	0.907	0.093
I86 Varicose veins of other sites	0.907	0.093
I52 Other heart disorders in diseases classified elsewhere	0.907	0.092
I48 Atrial fibrillation and flutter	0.907	0.092
I41 Myocarditis in diseases classified elsewhere	0.907	0.092
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.907	0.092
I32 Pericarditis in diseases classified elsewhere	0.907	0.092
I43 Cardiomyopathy in diseases classified elsewhere	0.907	0.092
I40 Acute myocarditis	0.907	0.092
Y35-Y36 Legal intervention and operations of war	0.907	0.092
X85-X99 Assault	0.907	0.092
W65-W74 Accidental drowning and submersion	0.907	0.092
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.907	0.092
X30-X39 Exposure to forces of nature	0.907	0.092
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.907	0.092
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.907	0.092
I37 Pulmonary valve disorders	0.907	0.092
I36 Nonrheumatic tricuspid valve disorders	0.907	0.092
Y10-Y34 Event of undetermined intent	0.907	0.092
X00-X09 Exposure to smoke, fire and flames	0.907	0.092
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.907	0.092
V98-V99 Other and unspecified transport accidents	0.907	0.092
V95-V97 Air and space transport accidents	0.907	0.092
V70-V79 Bus occupant injured in transport accident	0.907	0.092
W75-W84 Other accidental threats to breathing	0.907	0.092
X20-X29 Contact with venomous animals and plants	0.907	0.092
X10-X19 Contact with heat and hot substances	0.907	0.092
V01-V09 Pedestrian injured in transport accident	0.907	0.092
I33 Acute and subacute endocarditis	0.908	0.092
Y00-Y09 Assault	0.908	0.092
X58-X59 Accidental exposure to other and unspecified factors	0.908	0.092
X50-X57 Overexertion, travel and privation	0.908	0.092
I83 Varicose veins of lower extremities	0.908	0.092
V80-V89 Other land transport accidents	0.908	0.092
V40-V49 Car occupant injured in transport accident	0.908	0.092
V20-V29 Motorcycle rider injured in transport accident	0.908	0.092
X40-X49 Accidental poisoning by and exposure to noxious substances	0.908	0.092
W50-W64 Exposure to animate mechanical forces	0.908	0.092
I38 Endocarditis, valve unspecified	0.908	0.092
Y60-Y69 Misadventures to patients during surgical and medical care	0.908	0.092
X60-X84 Intentional self-harm	0.908	0.092
V10-V19 Pedal cyclist injured in transport accident	0.908	0.092
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.908	0.092
A75-A79 Rickettsioses	0.908	0.092
A70-A74 Other diseases caused by chlamydiae	0.908	0.092
B85-B89 Pediculosis, acariasis and other infestations	0.908	0.092
A20-A28 Certain zoonotic bacterial diseases	0.908	0.092
A65-A69 Other spirochaetal diseases	0.908	0.092
B99-B99 Other infectious diseases	0.908	0.092
B50-B64 Protozoal diseases	0.908	0.092
A15-A19 Tuberculosis	0.908	0.092
B65-B83 Helminthiases	0.908	0.092
B20-B24 Human immunodeficiency virus [HIV] disease	0.908	0.092
B90-B94 Sequelae of infectious and parasitic diseases	0.908	0.092
A80-A89 Viral infections of the central nervous system	0.908	0.092
A50-A64 Infections with a predominantly sexual mode of transmission	0.908	0.092
I31 Other diseases of pericardium	0.908	0.092
H91 Other hearing loss	0.908	0.092
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.908	0.092
Z86.7 Personal history of diseases of the circulatory system	0.908	0.091
B95-B98 Bacterial, viral and other infectious agents	0.909	0.091
I20 Angina pectoris	0.909	0.091
Chapter XV Pregnancy, childbirth and the puerperium	0.909	0.091
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.909	0.091
B25-B34 Other viral diseases	0.909	0.091
I34 Nonrheumatic mitral valve disorders	0.909	0.090
Z47 Other orthopaedic follow-up care	0.909	0.090
Z54 Convalescence	0.909	0.090
I88 Nonspecific lymphadenitis	0.910	0.090
I81 Portal vein thrombosis	0.910	0.090
R05 Cough	0.910	0.090
Z46 Fitting and adjustment of other devices	0.910	0.090
I85 Oesophageal varices	0.910	0.090
I47 Paroxysmal tachycardia	0.910	0.090
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.910	0.090
Z40 Prophylactic surgery	0.910	0.090
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.910	0.090
Z53 Persons encountering health services for specifie procedures, not carried out	0.910	0.090
I21 Acute myocardial infarction	0.910	0.089
Z43 Attention to artificial openings	0.911	0.089
K50-K52 Noninfective enteritis and colitis	0.911	0.089
Z50 Care involving use of rehabilitation procedures	0.911	0.089
I10 Essential (primary) hypertension	0.911	0.089
R06 Abnormalities of breathing	0.911	0.089
Z45 Adjustment and management of implanted device	0.912	0.088
Z42 Follow-up care involving plastic surgery	0.912	0.088
Z44 Fitting and adjustment of external prosthetic device	0.912	0.088
Z52 Donors of organs and tissues	0.912	0.088
Z49 Care involving dialysis	0.912	0.088
Z41 Procedures for purposes other than remedying health state	0.912	0.087
Z92.2 Personal history of long-term (current) use of other medicaments	0.913	0.087
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.913	0.087
I23 Certain current complications following acute myocardial infarction	0.913	0.087
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.913	0.087
Z48 Other surgical follow-up care	0.913	0.087
R11 Nausea and vomiting	0.913	0.087
I22 Subsequent myocardial infarction	0.913	0.087
R30-R39 Symptoms and signs involving the urinary system	0.913	0.086
S00 Superficial injury of head	0.913	0.086
I24 Other acute ischaemic heart diseases	0.914	0.086
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.914	0.086
D80-D89 Certain disorders involving the immune mechanism	0.914	0.086
D70-D77 Other diseases of blood and blood-forming organs	0.914	0.086
C51-C58 Malignant neoplasms of female genital organs	0.914	0.086
J43 Emphysema	0.914	0.086
S20 Superficial injury of thorax	0.914	0.086
L00-L08 Infections of the skin and subcutaneous tissue	0.914	0.086
E10-E14 Diabetes mellitus	0.914	0.086
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.914	0.086
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.914	0.085
H46-H48 Disorders of optic nerve and visual pathways	0.914	0.085
G96 Other disorders of central nervous system	0.914	0.085
E00-E07 Disorders of thyroid gland	0.914	0.085
R04 Haemorrhage from respiratory passages	0.915	0.085
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.915	0.085
F70-F79 Mental retardation	0.915	0.085
F99-F99 Unspecified mental disorder	0.915	0.085
F80-F89 Disorders of psychological development	0.915	0.085
C60-C63 Malignant neoplasms of male genital organs	0.915	0.085
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.915	0.085
F60-F69 Disorders of adult personality and behaviour	0.915	0.085
Z86.5 Personal history of other mental and behavioural disorders	0.915	0.085
J44 Other chronic obstructive pulmonary disease	0.915	0.085
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.915	0.085
D55-D59 Haemolytic anaemias	0.915	0.085
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.915	0.085
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.915	0.085
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.915	0.084
F00-F09 Organic, including symptomatic, mental disorders	0.915	0.084
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.916	0.084
Z86.1 Personal history of infectious and parasitic diseases	0.916	0.084
H92 Otalgia and effusion of ear	0.916	0.084
T88 Other complications of surgical and medical care, not elsewhere classified	0.916	0.084
S30 Superficial injury of abdomen, lower back and pelvis	0.916	0.084
P90-P96 Other disorders originating in the perinatal period	0.916	0.084
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.916	0.084
P75-P78 Digestive system disorders of fetus and newborn	0.916	0.084
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.916	0.084
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.916	0.084
P35-P39 Infections specific to the perinatal period	0.916	0.084
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.916	0.084
P05-P08 Disorders related to length of gestation and fetal growth	0.916	0.084
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.916	0.084
P10-P15 Birth trauma	0.916	0.084
L50-L54 Urticaria and erythema	0.916	0.084
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.916	0.084
H90 Conductive and sensorineural hearing loss	0.916	0.084
S24 Injury of nerves and spinal cord at thorax level	0.916	0.084
D50-D53 Nutritional anaemias	0.916	0.084
D60-D64 Aplastic and other anaemias	0.916	0.084
D37-D48 Neoplasms of uncertain or unknown behaviour	0.916	0.083
E40-E46 Malnutrition	0.916	0.083
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.917	0.083
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.917	0.083
H53-H54 Visual disturbances and blindness	0.917	0.083
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.917	0.083
L40-L45 Papulosquamous disorders	0.917	0.083
T85 Complications of other internal prosthetic devices, implants and grafts	0.917	0.083
E65-E68 Obesity and other hyperalimentation	0.917	0.083
H10-H13 Disorders of conjunctiva	0.917	0.083
H55-H59 Other disorders of eye and adnexa	0.917	0.083
S27 Injury of other and unspecified intrathoracic organs	0.917	0.083
L20-L30 Dermatitis and eczema	0.917	0.083
J46 Status asthmaticus	0.917	0.083
E50-E64 Other nutritional deficiencies	0.917	0.083
R02 Gangrene, not elsewhere classified	0.917	0.083
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.917	0.083
H40-H42 Glaucoma	0.917	0.082
L10-L14 Bullous disorders	0.917	0.082
S32 Fracture of lumbar spine and pelvis	0.917	0.082
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.917	0.082
H43-H45 Disorders of vitreous body and globe	0.918	0.082
R01 Cardiac murmurs and other cardiac sounds	0.918	0.082
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.918	0.082
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.918	0.082
C40-C41 Malignant neoplasms of bone and articular cartilage	0.918	0.082
J45 Asthma	0.918	0.082
S22 Fracture of rib(s), sternum and thoracic spine	0.918	0.082
H71 Cholesteatoma of middle ear	0.918	0.082
E70-E90 Metabolic disorders	0.918	0.082
S60 Superficial injury of wrist and hand	0.918	0.082
H25-H28 Disorders of lens	0.918	0.082
I13 Hypertensive heart and renal disease	0.918	0.082
T87 Complications peculiar to reattachment and amputation	0.918	0.082
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.918	0.082
I15 Secondary hypertension	0.918	0.082
H94 Other disorders of ear in diseases classified elsewhere	0.918	0.082
I11 Hypertensive heart disease	0.918	0.082
E20-E35 Disorders of other endocrine glands	0.918	0.082
T80 Complications following infusion, transfusion and therapeutic injection	0.918	0.082
T86 Failure and rejection of transplanted organs and tissues	0.918	0.082
S72 Fracture of femur	0.918	0.082
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.918	0.082
H69 Other disorders of Eustachian tube	0.918	0.082
Q35-Q37 Cleft lip and cleft palate	0.918	0.082
Q30-Q34 Congenital malformations of the respiratory system	0.918	0.082
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.918	0.081
H93 Other disorders of ear, not elsewhere classified	0.918	0.081
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.918	0.081
Q00-Q07 Congenital malformations of the nervous system	0.918	0.081
H74 Other disorders of middle ear and mastoid	0.918	0.081
R03 Abnormal blood-pressure reading, without diagnosis	0.918	0.081
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.918	0.081
K70-K77 Diseases of liver	0.919	0.081
Q38-Q45 Other congenital malformations of the digestive system	0.919	0.081
Q80-Q89 Other congenital malformations	0.919	0.081
Q50-Q56 Congenital malformations of genital organs	0.919	0.081
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.919	0.081
S26 Injury of heart	0.919	0.081
S25 Injury of blood vessels of thorax	0.919	0.081
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.919	0.081
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.919	0.081
H66 Suppurative and unspecified otitis media	0.919	0.081
S21 Open wound of thorax	0.919	0.081
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.919	0.081
S29 Other and unspecified injuries of thorax	0.919	0.081
Q60-Q64 Congenital malformations of the urinary system	0.919	0.081
H72 Perforation of tympanic membrane	0.919	0.081
I12 Hypertensive renal disease	0.919	0.081
H65 Nonsuppurative otitis media	0.919	0.081
Q20-Q28 Congenital malformations of the circulatory system	0.919	0.081
F40-F48 Neurotic, stress-related and somatoform disorders	0.919	0.081
L60-L75 Disorders of skin appendages	0.919	0.081
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.919	0.081
M06 Other rheumatoid arthritis	0.919	0.081
K65-K67 Diseases of peritoneum	0.919	0.081
G95 Other diseases of spinal cord	0.919	0.081
M79 Other soft tissue disorders, not elsewhere classified	0.919	0.081
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.919	0.081
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.919	0.081
Z88.1 Personal history of allergy to other antibiotic agents	0.919	0.080
C64-C68 Malignant neoplasms of urinary tract	0.919	0.080
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.919	0.080
H30-H36 Disorders of choroid and retina	0.919	0.080
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.919	0.080
C43-C44 Melanoma and other malignant neoplasms of skin	0.920	0.080
T17 Foreign body in respiratory tract	0.920	0.080
T18 Foreign body in alimentary tract	0.920	0.080
S67 Crushing injury of wrist and hand	0.920	0.080
G72 Other myopathies	0.920	0.080
I95 Hypotension	0.920	0.080
G93 Other disorders of brain	0.920	0.080
J41 Simple and mucopurulent chronic bronchitis	0.920	0.080
M25 Other joint disorders, not elsewhere classified	0.920	0.080
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.920	0.080
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.920	0.080
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.920	0.080
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.920	0.080
S37 Injury of urinary and pelvic organs	0.920	0.080
S36 Injury of intra-abdominal organs	0.920	0.080
K90-K93 Other diseases of the digestive system	0.920	0.080
J42 Unspecified chronic bronchitis	0.920	0.080
S31 Open wound of abdomen, lower back and pelvis	0.920	0.079
R00 Abnormalities of heart beat	0.920	0.079
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.920	0.079
F30-F39 Mood [affective] disorders	0.920	0.079
J18 Pneumonia, organism unspecified	0.920	0.079
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.920	0.079
H68 Eustachian salpingitis and obstruction	0.920	0.079
H67 Otitis media in diseases classified elsewhere	0.920	0.079
T94 Sequelae of injuries involving multiple and unspecified body regions	0.920	0.079
G82 Paraplegia and tetraplegia	0.920	0.079
H70 Mastoiditis and related conditions	0.921	0.079
S01 Open wound of head	0.921	0.079
S40 Superficial injury of shoulder and upper arm	0.921	0.079
G09 Sequelae of inflammatory diseases of central nervous system	0.921	0.079
J40 Bronchitis, not specified as acute or chronic	0.921	0.079
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.921	0.079
H73 Other disorders of tympanic membrane	0.921	0.079
I27 Other pulmonary heart diseases	0.921	0.079
D00-D09 In situ neoplasms	0.921	0.079
S08 Traumatic amputation of part of head	0.921	0.079
S07 Crushing injury of head	0.921	0.079
S04 Injury of cranial nerves	0.921	0.079
S03 Dislocation, sprain and strain of joints and ligaments of head	0.921	0.079
J13 Pneumonia due to Streptococcus pneumoniae	0.921	0.079
M35 Other systemic involvement of connective tissue	0.921	0.079
T93 Sequelae of injuries of lower limb	0.921	0.079
T09 Other injuries of spine and trunk, level unspecified	0.921	0.079
S05 Injury of eye and orbit	0.921	0.079
Z57 Occupational exposure to risk-factors	0.921	0.079
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.921	0.079
S10 Superficial injury of neck	0.921	0.079
R17 Unspecified jaundice	0.921	0.079
M81 Osteoporosis without pathological fracture	0.921	0.079
G92 Toxic encephalopathy	0.921	0.079
G98 Other disorders of nervous system, not elsewhere classified	0.921	0.079
G94 Other disorders of brain in diseases classified elsewhere	0.921	0.079
S06 Intracranial injury	0.921	0.079
G90 Disorders of autonomic nervous system	0.921	0.078
G06 Intracranial and intraspinal abscess and granuloma	0.921	0.078
G00 Bacterial meningitis, not elsewhere classified	0.921	0.078
H83 Other diseases of inner ear	0.921	0.078
H61 Other disorders of external ear	0.921	0.078
I99 Other and unspecified disorders of circulatory system	0.921	0.078
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.921	0.078
G91 Hydrocephalus	0.921	0.078
L80-L99 Other disorders of the skin and subcutaneous tissue	0.921	0.078
I98 Other disorders of circulatory system in diseases classified elsewhere	0.922	0.078
J11 Influenza, virus not identified	0.922	0.078
S02 Fracture of skull and facial bones	0.922	0.078
G45 Transient cerebral ischaemic attacks and related syndromes	0.922	0.078
I62 Other nontraumatic intracranial haemorrhage	0.922	0.078
J47 Bronchiectasis	0.922	0.078
R18 Ascites	0.922	0.078
S61 Open wound of wrist and hand	0.922	0.078
T15 Foreign body on external eye	0.922	0.078
T19 Foreign body in genito-urinary tract	0.922	0.078
T16 Foreign body in ear	0.922	0.078
G99 Other disorders of nervous system in diseases classified elsewhere	0.922	0.078
G70 Myasthenia gravis and other myoneural disorders	0.922	0.078
S09 Other and unspecified injuries of head	0.922	0.078
Z85.4 Personal history of malignant neoplasm of genital organs	0.922	0.078
S65 Injury of blood vessels at wrist and hand level	0.922	0.078
T78 Adverse effects, not elsewhere classified	0.922	0.078
S78 Traumatic amputation of hip and thigh	0.922	0.078
S77 Crushing injury of hip and thigh	0.922	0.078
S75 Injury of blood vessels at hip and thigh level	0.922	0.078
S74 Injury of nerves at hip and thigh level	0.922	0.078
S69 Other and unspecified injuries of wrist and hand	0.922	0.078
S76 Injury of muscle and tendon at hip and thigh level	0.922	0.078
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.922	0.078
S71 Open wound of hip and thigh	0.922	0.078
I02 Rheumatic chorea	0.922	0.078
I01 Rheumatic fever with heart involvement	0.922	0.078
R07.4 Chest pain, unspecified	0.922	0.078
I00 Rheumatic fever without mention of heart involvement	0.922	0.078
I60 Subarachnoid haemorrhage	0.922	0.078
S79 Other and unspecified injuries of hip and thigh	0.922	0.078
S68 Traumatic amputation of wrist and hand	0.922	0.078
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.922	0.078
C50-C50 Malignant neoplasm of breast	0.922	0.078
R12 Heartburn	0.922	0.078
S70 Superficial injury of hip and thigh	0.922	0.078
G43 Migraine	0.922	0.078
I78 Diseases of capillaries	0.922	0.077
S64 Injury of nerves at wrist and hand level	0.922	0.077

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations