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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4800316
log Bayes Factor = 9.39887
Chromosome 18   position 26,609,089  (GRCh37) Explore rs4800316 on Ensembl!
Variant rs4800316 is part of Cluster X0084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.995 0.005 0.000
Chapter II Neoplasms
0.992 0.008 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
S00-S09 Injuries to the head
0.992 0.008 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.991 0.009 0.000
C34 Malignant neoplasm of bronchus and lung
0.990 0.010 0.000
Chapter V Mental and behavioural disorders
0.981 0.019 0.000
D10-D36 Benign neoplasms
0.979 0.021 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.979 0.021 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.978 0.022 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.978 0.022 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.977 0.023 0.000
T39.1 4-Aminophenol derivatives
0.976 0.024 0.000
C34.1 Upper lobe, bronchus or lung
0.974 0.026 0.000
J40-J47 Chronic lower respiratory diseases
0.970 0.030 0.000
F10.1 Harmful use
0.968 0.032 0.000
D12.0 Caecum
0.962 0.038 0.000
J44 Other chronic obstructive pulmonary disease
0.962 0.038 0.000
Chapter XX External causes of morbidity and mortality
0.961 0.039 0.000
Chapter XIV Diseases of the genitourinary system
0.959 0.041 0.000
D12.3 Transverse colon
0.959 0.041 0.000
S50-S59 Injuries to the elbow and forearm
0.957 0.043 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.957 0.043 0.000
T40.2 Other opioids
0.951 0.049 0.000
Chapter I Certain infectious and parasitic diseases
0.951 0.049 0.000
S60-S69 Injuries to the wrist and hand
0.942 0.058 0.000
B35-B49 Mycoses
0.940 0.060 0.000
C34.9 Bronchus or lung, unspecified
0.938 0.062 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.938 0.062 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.935 0.065 0.000
N30-N39 Other diseases of urinary system
0.929 0.071 0.000
S40-S49 Injuries to the shoulder and upper arm
0.928 0.072 0.000
J43 Emphysema
0.925 0.075 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.924 0.076 0.000
D12.2 Ascending colon
0.923 0.077 0.000
B37 Candidiasis
0.918 0.082 0.000
N20-N23 Urolithiasis
0.913 0.087 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.910 0.090 0.000
S62 Fracture at wrist and hand level
0.909 0.091 0.000
J90-J94 Other diseases of pleura
0.903 0.097 0.000
S06 Intracranial injury
0.902 0.098 0.000
S52 Fracture of forearm
0.901 0.099 0.000
T51 Toxic effect of alcohol
0.900 0.100 0.000
N39 Other disorders of urinary system
0.898 0.102 0.000
N60-N64 Disorders of breast
0.893 0.107 0.000
B37.8 Candidiasis of other sites
0.892 0.108 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.891 0.109 0.000
S10-S19 Injuries to the neck
0.891 0.109 0.000
J43.9 Emphysema, unspecified
0.891 0.109 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.890 0.110 0.000
C34.3 Lower lobe, bronchus or lung
0.889 0.111 0.000
T79-T79 Certain early complications of trauma
0.887 0.113 0.000
Chapter VI Diseases of the nervous system
0.882 0.118 0.000
F10.3 Withdrawal state
0.875 0.125 0.000
M20-M25 Other joint disorders
0.872 0.128 0.000
N39.4 Other specified urinary incontinence
0.870 0.130 0.000
T51.0 Ethanol
0.868 0.132 0.000
S05 Injury of eye and orbit
0.867 0.133 0.000
S52.6 Fracture of lower end of both ulna and radius
0.865 0.135 0.000
N64 Other disorders of breast
0.864 0.136 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.862 0.138 0.000
C45 Mesothelioma
0.862 0.138 0.000
N60 Benign mammary dysplasia
0.860 0.140 0.000
S02 Fracture of skull and facial bones
0.860 0.140 0.000
S09 Other and unspecified injuries of head
0.858 0.142 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.857 0.143 0.000
S62.6 Fracture of other finger
0.854 0.146 0.000
J94 Other pleural conditions
0.853 0.147 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.853 0.147 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.853 0.147 0.000
F10.0 Acute intoxication
0.851 0.149 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.847 0.153 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.845 0.155 0.000
N21 Calculus of lower urinary tract
0.844 0.156 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.840 0.160 0.000
D16 Benign neoplasm of bone and articular cartilage
0.839 0.161 0.000
N25-N29 Other disorders of kidney and ureter
0.838 0.162 0.000
S90-S99 Injuries to the ankle and foot
0.837 0.163 0.000
D10 Benign neoplasm of mouth and pharynx
0.836 0.164 0.000
T39.0 Salicylates
0.835 0.165 0.000
B44 Aspergillosis
0.834 0.166 0.000
B25-B34 Other viral diseases
0.834 0.166 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.832 0.168 0.000
M24 Other specific joint derangements
0.831 0.169 0.000
S50 Superficial injury of forearm
0.831 0.169 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.830 0.170 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.829 0.171 0.000
J95-J99 Other diseases of the respiratory system
0.828 0.172 0.000
M21 Other acquired deformities of limbs
0.826 0.174 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.822 0.178 0.000
G90-G99 Other disorders of the nervous system
0.819 0.181 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.818 0.182 0.000
T40.4 Other synthetic narcotics
0.817 0.182 0.000
S62.60 Fracture of other finger (closed)
0.817 0.183 0.000
D29 Benign neoplasm of male genital organs
0.816 0.184 0.000
X60-X84 Intentional self-harm
0.816 0.184 0.000
S42 Fracture of shoulder and upper arm
0.816 0.184 0.000
N32 Other disorders of bladder
0.812 0.188 0.000
V10-V19 Pedal cyclist injured in transport accident
0.810 0.190 0.000
D37.4 Colon
0.806 0.194 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.806 0.194 0.000
D12.1 Appendix
0.804 0.196 0.000
D11 Benign neoplasm of major salivary glands
0.803 0.197 0.000
M34 Systemic sclerosis
0.802 0.198 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.801 0.199 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.797 0.203 0.000
N64.9 Disorder of breast, unspecified
0.796 0.204 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.796 0.204 0.000
N21.0 Calculus in bladder
0.795 0.205 0.000
B37.9 Candidiasis, unspecified
0.794 0.206 0.000
N23 Unspecified renal colic
0.793 0.207 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.792 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.208 0.000
D12.9 Anus and anal canal
0.790 0.210 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.788 0.212 0.000
J91 Pleural effusion in conditions classified elsewhere
0.787 0.213 0.000
S62.4 Multiple fractures of metacarpal bones
0.787 0.213 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.786 0.214 0.000
D24 Benign neoplasm of breast
0.786 0.214 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.786 0.214 0.000
Y00-Y09 Assault
0.786 0.214 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.785 0.215 0.000
M25 Other joint disorders, not elsewhere classified
0.784 0.216 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.780 0.220 0.000
N39.9 Disorder of urinary system, unspecified
0.780 0.220 0.000
C34.0 Main bronchus
0.780 0.220 0.000
Y44 Agents primarily affecting blood constituents
0.778 0.222 0.000
S67 Crushing injury of wrist and hand
0.776 0.224 0.000
W20-W49 Exposure to inanimate mechanical forces
0.776 0.224 0.000
S01 Open wound of head
0.775 0.225 0.000
G90 Disorders of autonomic nervous system
0.773 0.227 0.000
M65-M68 Disorders of synovium and tendon
0.772 0.228 0.000
G20-G26 Extrapyramidal and movement disorders
0.771 0.229 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.771 0.229 0.000
Y45.0 Opioids and related analgesics
0.770 0.230 0.000
B65-B83 Helminthiases
0.769 0.231 0.000
T58 Toxic effect of carbon monoxide
0.768 0.232 0.000
B49 Unspecified mycosis
0.767 0.233 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.767 0.233 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.767 0.233 0.000
J09-J18 Influenza and pneumonia
0.766 0.234 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.765 0.235 0.000
J94.2 Haemothorax
0.764 0.236 0.000
N64.8 Other specified disorders of breast
0.764 0.236 0.000
F10.2 Dependence syndrome
0.764 0.236 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.763 0.237 0.000
S09.9 Unspecified injury of head
0.763 0.237 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.762 0.238 0.000
S00 Superficial injury of head
0.762 0.238 0.000
N60.3 Fibrosclerosis of breast
0.760 0.239 0.000
J94.8 Other specified pleural conditions
0.758 0.242 0.000
N99-N99 Other disorders of the genitourinary system
0.757 0.243 0.000
B37.1 Pulmonary candidiasis
0.756 0.244 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.755 0.245 0.000
S06.8 Other intracranial injuries
0.753 0.247 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.752 0.248 0.000
S06.5 Traumatic subdural haemorrhage
0.751 0.248 0.000
T63 Toxic effect of contact with venomous animals
0.750 0.250 0.000
T46.1 Calcium-channel blockers
0.749 0.250 0.000
F11 Mental and behavioural disorders due to use of opioids
0.748 0.252 0.000
Y45.1 Salicylates
0.746 0.254 0.000
D34 Benign neoplasm of thyroid gland
0.746 0.254 0.000
B50-B64 Protozoal diseases
0.744 0.255 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.743 0.257 0.000
S52.1 Fracture of upper end of radius
0.743 0.257 0.000
C45.7 Mesothelioma of other sites
0.742 0.258 0.000
M50-M54 Other dorsopathies
0.742 0.258 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.740 0.260 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.738 0.262 0.000
F10.9 Unspecified mental and behavioural disorder
0.737 0.263 0.000
S69 Other and unspecified injuries of wrist and hand
0.735 0.265 0.000
N60.4 Mammary duct ectasia
0.734 0.266 0.000
C45.0 Mesothelioma of pleura
0.734 0.266 0.000
N39.8 Other specified disorders of urinary system
0.733 0.267 0.000
S62.2 Fracture of first metacarpal bone
0.732 0.268 0.000
S42.2 Fracture of upper end of humerus
0.731 0.269 0.000
S10 Superficial injury of neck
0.730 0.270 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.730 0.270 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.728 0.272 0.000
M25.5 Pain in joint
0.728 0.272 0.000
J30-J39 Other diseases of upper respiratory tract
0.727 0.273 0.000
D30 Benign neoplasm of urinary organs
0.726 0.274 0.000
F10.4 Withdrawal state with delirium
0.725 0.275 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.725 0.275 0.000
S50.9 Superficial injury of forearm, unspecified
0.724 0.276 0.000
D26 Other benign neoplasms of uterus
0.723 0.277 0.000
S41 Open wound of shoulder and upper arm
0.723 0.277 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.723 0.277 0.000
X50-X57 Overexertion, travel and privation
0.722 0.278 0.000
B34 Viral infection of unspecified site
0.721 0.278 0.000
M25.51 Pain in joint (Shoulder region)
0.721 0.279 0.000
S02.4 Fracture of malar and maxillary bones
0.720 0.280 0.000
D33.3 Cranial nerves
0.718 0.282 0.000
J86 Pyothorax
0.717 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
Chapter IX Diseases of the circulatory system
0.716 0.284 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.716 0.284 0.000
B44.1 Other pulmonary aspergillosis
0.716 0.284 0.000
S70-S79 Injuries to the hip and thigh
0.715 0.285 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.714 0.286 0.000
T39.4 Antirheumatics, not elsewhere classified
0.714 0.286 0.000
T39.2 Pyrazolone derivatives
0.714 0.286 0.000
M21.0 Valgus deformity, not elsewhere classified
0.713 0.287 0.000
S56 Injury of muscle and tendon at forearm level
0.712 0.288 0.000
S06.2 Diffuse brain injury
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.288 0.000
S08 Traumatic amputation of part of head
0.711 0.289 0.000
S07 Crushing injury of head
0.711 0.289 0.000
S04 Injury of cranial nerves
0.711 0.289 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.711 0.289 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.711 0.289 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.711 0.289 0.000
M80-M85 Disorders of bone density and structure
0.711 0.289 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.710 0.290 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.710 0.290 0.000
C31 Malignant neoplasm of accessory sinuses
0.710 0.290 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.710 0.290 0.000
C37 Malignant neoplasm of thymus
0.710 0.290 0.000
C33 Malignant neoplasm of trachea
0.710 0.290 0.000
C34.8 Overlapping lesion of bronchus and lung
0.710 0.290 0.000
C34.2 Middle lobe, bronchus or lung
0.710 0.290 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.710 0.290 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.709 0.291 0.000
B15-B19 Viral hepatitis
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.291 0.000
Y52 Agents primarily affecting the cardiovascular system
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.706 0.294 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.704 0.296 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
S62.7 Multiple fractures of fingers
0.703 0.297 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.703 0.297 0.000
F70-F79 Mental retardation
0.703 0.297 0.000
N34 Urethritis and urethral syndrome
0.703 0.297 0.000
S64 Injury of nerves at wrist and hand level
0.703 0.297 0.000
D31 Benign neoplasm of eye and adnexa
0.702 0.298 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.702 0.298 0.000
D19 Benign neoplasm of mesothelial tissue
0.702 0.298 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.702 0.298 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.702 0.298 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.702 0.298 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.702 0.298 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.702 0.298 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.702 0.298 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.702 0.298 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.701 0.299 0.000
T40.8 Lysergide [LSD]
0.701 0.299 0.000
T40.7 Cannabis (derivatives)
0.701 0.299 0.000
T40.6 Other and unspecified narcotics
0.701 0.299 0.000
T40.5 Cocaine
0.701 0.299 0.000
T40.3 Methadone
0.701 0.299 0.000
T40.1 Heroin
0.701 0.299 0.000
T40.0 Opium
0.701 0.299 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.701 0.299 0.000
F10.8 Other mental and behavioural disorders
0.701 0.299 0.000
F10.7 Residual and late-onset psychotic disorder
0.701 0.299 0.000
F10.6 Amnesic syndrome
0.701 0.299 0.000
F10.5 Psychotic disorder
0.701 0.299 0.000
X20-X29 Contact with venomous animals and plants
0.700 0.300 0.000
S62.40 Multiple fractures of metacarpal bones (closed)
0.700 0.300 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.700 0.300 0.000
D29.0 Penis
0.700 0.300 0.000
M24.5 Contracture of joint
0.699 0.300 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.699 0.301 0.000
M24.2 Disorder of ligament
0.698 0.302 0.000
S02.1 Fracture of base of skull
0.697 0.302 0.000
S12 Fracture of neck
0.697 0.303 0.000
M34.1 CR(E)ST syndrome
0.697 0.303 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.697 0.303 0.000
J41 Simple and mucopurulent chronic bronchitis
0.696 0.304 0.000
J42 Unspecified chronic bronchitis
0.695 0.305 0.000
N32.9 Bladder disorder, unspecified
0.695 0.305 0.000
D16.3 Short bones of lower limb
0.694 0.306 0.000
N32.3 Diverticulum of bladder
0.694 0.306 0.000
C45.9 Mesothelioma, unspecified
0.692 0.308 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.691 0.309 0.000
F99-F99 Unspecified mental disorder
0.691 0.309 0.000
D10.1 Tongue
0.691 0.309 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.691 0.309 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.691 0.309 0.000
N64.4 Mastodynia
0.691 0.309 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.690 0.310 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.690 0.310 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.690 0.310 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.689 0.311 0.000
D00-D09 In situ neoplasms
0.689 0.311 0.000
A80-A89 Viral infections of the central nervous system
0.688 0.312 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.688 0.312 0.000
N60.1 Diffuse cystic mastopathy
0.687 0.313 0.000
S92 Fracture of foot, except ankle
0.686 0.313 0.000
S59 Other and unspecified injuries of forearm
0.686 0.314 0.000
S58 Traumatic amputation of forearm
0.686 0.314 0.000
S57 Crushing injury of forearm
0.686 0.314 0.000
S55 Injury of blood vessels at forearm level
0.686 0.314 0.000
S54 Injury of nerves at forearm level
0.686 0.314 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.686 0.314 0.000
S02.8 Fractures of other skull and facial bones
0.686 0.314 0.000
T65 Toxic effect of other and unspecified substances
0.686 0.314 0.000
T62 Toxic effect of other noxious substances eaten as food
0.686 0.314 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.686 0.314 0.000
T60 Toxic effect of pesticides
0.686 0.314 0.000
T59 Toxic effect of other gases, fumes and vapours
0.686 0.314 0.000
T57 Toxic effect of other inorganic substances
0.686 0.314 0.000
T56 Toxic effect of metals
0.686 0.314 0.000
T54 Toxic effect of corrosive substances
0.686 0.314 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.686 0.314 0.000
T52 Toxic effect of organic solvents
0.686 0.314 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.686 0.314 0.000
T55 Toxic effect of soaps and detergents
0.686 0.314 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.686 0.314 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.686 0.314 0.000
N60.9 Benign mammary dysplasia, unspecified
0.685 0.315 0.000
B44.9 Aspergillosis, unspecified
0.684 0.316 0.000
M50 Cervical disk disorders
0.684 0.316 0.000
N39.3 Stress incontinence
0.682 0.318 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.682 0.318 0.000
N26 Unspecified contracted kidney
0.682 0.318 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.681 0.318 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.681 0.318 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.681 0.318 0.000
A75-A79 Rickettsioses
0.681 0.318 0.000
A70-A74 Other diseases caused by chlamydiae
0.681 0.318 0.000
A65-A69 Other spirochaetal diseases
0.681 0.318 0.000
A20-A28 Certain zoonotic bacterial diseases
0.681 0.318 0.000
A15-A19 Tuberculosis
0.681 0.318 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.681 0.319 0.000
S52.2 Fracture of shaft of ulna
0.680 0.320 0.000
G51 Facial nerve disorders
0.680 0.320 0.000
D28.1 Vagina
0.679 0.321 0.000
Y54.3 Benzothiadiazine derivatives
0.679 0.321 0.000
F80-F89 Disorders of psychological development
0.678 0.322 0.000
D35.2 Pituitary gland
0.678 0.322 0.000
B27 Infectious mononucleosis
0.677 0.323 0.000
D37.7 Other digestive organs
0.677 0.323 0.000
D11.0 Parotid gland
0.676 0.324 0.000
J17 Pneumonia in diseases classified elsewhere
0.676 0.324 0.000
S65 Injury of blood vessels at wrist and hand level
0.675 0.325 0.000
J43.2 Centrilobular emphysema
0.675 0.325 0.000
D32 Benign neoplasm of meninges
0.674 0.326 0.000
B48 Other mycoses, not elsewhere classified
0.674 0.326 0.000
B47 Mycetoma
0.674 0.326 0.000
B46 Zygomycosis
0.674 0.326 0.000
B45 Cryptococcosis
0.674 0.326 0.000
B43 Chromomycosis and phaeomycotic abscess
0.674 0.326 0.000
B42 Sporotrichosis
0.674 0.326 0.000
B41 Paracoccidioidomycosis
0.674 0.326 0.000
B40 Blastomycosis
0.674 0.326 0.000
B39 Histoplasmosis
0.674 0.326 0.000
B38 Coccidioidomycosis
0.674 0.326 0.000
B36 Other superficial mycoses
0.674 0.326 0.000
D16.4 Bones of skull and face
0.674 0.326 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.674 0.326 0.000
J38.3 Other diseases of vocal cords
0.673 0.327 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.673 0.327 0.000
G90.2 Horner's syndrome
0.672 0.328 0.000
D33.2 Brain, unspecified
0.672 0.328 0.000
Y59 Other and unspecified vaccines and biological substances
0.670 0.330 0.000
Y58 Bacterial vaccines
0.670 0.330 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.670 0.330 0.000
Y48 Anaesthetics and therapeutic gases
0.670 0.330 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.670 0.330 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.670 0.330 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
S42.20 Fracture of upper end of humerus (closed)
0.670 0.330 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.670 0.330 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.670 0.330 0.000
B99-B99 Other infectious diseases
0.670 0.330 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.669 0.331 0.000
D10.3 Other and unspecified parts of mouth
0.669 0.331 0.000
S68 Traumatic amputation of wrist and hand
0.668 0.332 0.000
M33 Dermatopolymyositis
0.668 0.332 0.000
S19 Other and unspecified injuries of neck
0.668 0.332 0.000
M21.3 Wrist or foot drop (acquired)
0.667 0.333 0.000
S32 Fracture of lumbar spine and pelvis
0.667 0.333 0.000
N64.5 Other signs and symptoms in breast
0.666 0.334 0.000
N37 Urethral disorders in diseases classified elsewhere
0.666 0.334 0.000
N33 Bladder disorders in diseases classified elsewhere
0.666 0.334 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.665 0.335 0.000
Y44.2 Anticoagulants
0.665 0.335 0.000
S48 Traumatic amputation of shoulder and upper arm
0.665 0.335 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.665 0.335 0.000
S44 Injury of nerves at shoulder and upper arm level
0.665 0.335 0.000
S47 Crushing injury of shoulder and upper arm
0.665 0.335 0.000
V20-V29 Motorcycle rider injured in transport accident
0.665 0.335 0.000
S01.7 Multiple open wounds of head
0.665 0.335 0.000
S02.6 Fracture of mandible
0.663 0.337 0.000
J43.8 Other emphysema
0.663 0.337 0.000
J43.1 Panlobular emphysema
0.663 0.337 0.000
J43.0 MacLeod's syndrome
0.663 0.337 0.000
N60.2 Fibroadenosis of breast
0.662 0.338 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.662 0.338 0.000
C46 Kaposi's sarcoma
0.662 0.338 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.662 0.338 0.000
Chapter VIII Diseases of the ear and mastoid process
0.662 0.338 0.000
M34.9 Systemic sclerosis, unspecified
0.661 0.339 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.661 0.339 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.660 0.340 0.000
C32 Malignant neoplasm of larynx
0.659 0.340 0.000
M67 Other disorders of synovium and tendon
0.659 0.341 0.000
J98 Other respiratory disorders
0.659 0.341 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.658 0.342 0.000
B37.7 Candidal septicaemia
0.658 0.342 0.000
B37.6 Candidal endocarditis
0.658 0.342 0.000
B37.5 Candidal meningitis
0.658 0.342 0.000
B37.4 Candidiasis of other urogenital sites
0.658 0.342 0.000
B37.2 Candidiasis of skin and nail
0.658 0.342 0.000
M21.2 Flexion deformity
0.658 0.342 0.000
W29 Contact with other powered hand tools and household machinery
0.658 0.342 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.657 0.343 0.000
T98 Sequelae of other and unspecified effects of external causes
0.656 0.343 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.655 0.345 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.655 0.345 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.653 0.347 0.000
I77 Other disorders of arteries and arterioles
0.653 0.347 0.000
Y00 Assault by blunt object
0.652 0.348 0.000
M00-M03 Infectious arthropathies
0.652 0.348 0.000
M21.4 Flat foot [pes planus] (acquired)
0.652 0.348 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.652 0.348 0.000
S62.1 Fracture of other carpal bone(s)
0.651 0.348 0.000
S06.3 Focal brain injury
0.651 0.349 0.000
Y45.2 Propionic acid derivatives
0.651 0.349 0.000
G20 Parkinson's disease
0.651 0.349 0.000
G95 Other diseases of spinal cord
0.651 0.349 0.000
M24.1 Other articular cartilage disorders
0.650 0.350 0.000
T79.7 Traumatic subcutaneous emphysema
0.649 0.351 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.649 0.351 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.648 0.352 0.000
N20 Calculus of kidney and ureter
0.648 0.352 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.647 0.353 0.000
S06.9 Intracranial injury, unspecified
0.647 0.353 0.000
S06.7 Intracranial injury with prolonged coma
0.647 0.353 0.000
S06.4 Epidural haemorrhage
0.647 0.353 0.000
S06.1 Traumatic cerebral oedema
0.647 0.353 0.000
S52.9 Fracture of forearm, part unspecified
0.646 0.354 0.000
S52.7 Multiple fractures of forearm
0.646 0.354 0.000
S52.4 Fracture of shafts of both ulna and radius
0.646 0.354 0.000
S52.3 Fracture of shaft of radius
0.646 0.354 0.000
T17 Foreign body in respiratory tract
0.646 0.354 0.000
Y40 Systemic antibiotics
0.646 0.354 0.000
T51.8 Other alcohols
0.645 0.355 0.000
T51.3 Fusel oil
0.645 0.355 0.000
T51.2 2-Propanol
0.645 0.355 0.000
T51.1 Methanol
0.645 0.355 0.000
T43.2 Other and unspecified antidepressants
0.645 0.355 0.000
N39.2 Orthostatic proteinuria, unspecified
0.644 0.356 0.000
N39.1 Persistent proteinuria, unspecified
0.644 0.356 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.644 0.356 0.000
S02.5 Fracture of tooth
0.642 0.358 0.000
G24 Dystonia
0.641 0.359 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.641 0.359 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.640 0.360 0.000
N25 Disorders resulting from impaired renal tubular function
0.640 0.360 0.000
Chapter XXII Codes for special purposes
0.640 0.360 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.639 0.361 0.000
B80 Enterobiasis
0.639 0.361 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.639 0.361 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.639 0.361 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.639 0.361 0.000
T46.7 Peripheral vasodilators
0.639 0.361 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.639 0.361 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.639 0.361 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.639 0.361 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.639 0.361 0.000
S17 Crushing injury of neck
0.639 0.361 0.000
S15 Injury of blood vessels at neck level
0.639 0.361 0.000
S14 Injury of nerves and spinal cord at neck level
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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