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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4831269
log Bayes Factor = 8.89457
Chromosome 8   position 13,898,600  (GRCh37) Explore rs4831269 on Ensembl!
Variant rs4831269 is part of Cluster X0133

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
C18 Malignant neoplasm of colon
0.999 0.001 0.000
N60-N64 Disorders of breast
0.995 0.005 0.000
N30-N39 Other diseases of urinary system
0.994 0.006 0.000
C64-C68 Malignant neoplasms of urinary tract
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.988 0.012 0.000
C67 Malignant neoplasm of bladder
0.981 0.019 0.000
N30 Cystitis
0.979 0.021 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.976 0.024 0.000
N17-N19 Renal failure
0.973 0.027 0.000
N64 Other disorders of breast
0.964 0.036 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.961 0.039 0.000
C18.7 Sigmoid colon
0.960 0.040 0.000
N39 Other disorders of urinary system
0.955 0.045 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.954 0.046 0.000
N17 Acute renal failure
0.953 0.047 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.950 0.050 0.000
Chapter VI Diseases of the nervous system
0.947 0.053 0.000
N61 Inflammatory disorders of breast
0.943 0.057 0.000
C18.9 Colon, unspecified
0.930 0.070 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.929 0.071 0.000
G20-G26 Extrapyramidal and movement disorders
0.926 0.074 0.000
C67.9 Bladder, unspecified
0.922 0.078 0.000
N39.0 Urinary tract infection, site not specified
0.918 0.082 0.000
N30.8 Other cystitis
0.916 0.084 0.000
B25-B34 Other viral diseases
0.913 0.087 0.000
N64.9 Disorder of breast, unspecified
0.909 0.091 0.000
G20 Parkinson's disease
0.909 0.091 0.000
N17.9 Acute renal failure, unspecified
0.908 0.092 0.000
Chapter XX External causes of morbidity and mortality
0.906 0.094 0.000
S20-S29 Injuries to the thorax
0.899 0.101 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.896 0.104 0.000
C18.6 Descending colon
0.893 0.107 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.885 0.115 0.000
Chapter V Mental and behavioural disorders
0.873 0.127 0.000
N19 Unspecified renal failure
0.873 0.127 0.000
B07 Viral warts
0.872 0.128 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.872 0.128 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.871 0.129 0.000
C18.4 Transverse colon
0.871 0.129 0.000
N64.5 Other signs and symptoms in breast
0.870 0.130 0.000
Chapter X Diseases of the respiratory system
0.869 0.131 0.000
M91-M94 Chondropathies
0.869 0.131 0.000
N17.0 Acute renal failure with tubular necrosis
0.867 0.133 0.000
C67.2 Lateral wall of bladder
0.864 0.136 0.000
N30.2 Other chronic cystitis
0.856 0.144 0.000
A30-A49 Other bacterial diseases
0.856 0.144 0.000
C18.2 Ascending colon
0.854 0.146 0.000
J00-J06 Acute upper respiratory infections
0.853 0.147 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.853 0.147 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.851 0.149 0.000
B34 Viral infection of unspecified site
0.850 0.150 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.850 0.150 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.849 0.151 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.847 0.153 0.000
N00-N08 Glomerular diseases
0.844 0.156 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.844 0.156 0.000
N30.0 Acute cystitis
0.841 0.159 0.000
B00 Herpesviral [herpes simplex] infections
0.841 0.159 0.000
Y95 Nosocomial condition
0.841 0.159 0.000
Chapter VIII Diseases of the ear and mastoid process
0.841 0.159 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.840 0.160 0.000
J06.9 Acute upper respiratory infection, unspecified
0.839 0.161 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.838 0.162 0.000
C25 Malignant neoplasm of pancreas
0.838 0.162 0.000
C15 Malignant neoplasm of oesophagus
0.837 0.163 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.835 0.165 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.834 0.166 0.000
N36 Other disorders of urethra
0.828 0.172 0.000
Q80-Q89 Other congenital malformations
0.826 0.174 0.000
N39.3 Stress incontinence
0.822 0.178 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.822 0.178 0.000
C67.3 Anterior wall of bladder
0.821 0.179 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.820 0.180 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.820 0.180 0.000
N20-N23 Urolithiasis
0.819 0.181 0.000
M45-M49 Spondylopathies
0.812 0.188 0.000
G70-G73 Diseases of myoneural junction and muscle
0.810 0.190 0.000
F20 Schizophrenia
0.808 0.192 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.808 0.192 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.806 0.194 0.000
S22.0 Fracture of thoracic vertebra
0.803 0.197 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.800 0.200 0.000
C45 Mesothelioma
0.799 0.201 0.000
C67.4 Posterior wall of bladder
0.797 0.203 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.797 0.203 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.796 0.204 0.000
B34.9 Viral infection, unspecified
0.796 0.204 0.000
Q50-Q56 Congenital malformations of genital organs
0.795 0.205 0.000
C16 Malignant neoplasm of stomach
0.794 0.205 0.000
Q00-Q07 Congenital malformations of the nervous system
0.794 0.206 0.000
N21 Calculus of lower urinary tract
0.792 0.208 0.000
N60 Benign mammary dysplasia
0.789 0.211 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.788 0.212 0.000
S70-S79 Injuries to the hip and thigh
0.787 0.213 0.000
Chapter XXI Factors influencing health status and contact with health services
0.784 0.216 0.000
G90-G99 Other disorders of the nervous system
0.784 0.216 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.783 0.217 0.000
M86-M90 Other osteopathies
0.781 0.219 0.000
C18.3 Hepatic flexure
0.778 0.222 0.000
S22.4 Multiple fractures of ribs
0.776 0.224 0.000
M60-M63 Disorders of muscles
0.775 0.225 0.000
N62 Hypertrophy of breast
0.774 0.226 0.000
S27 Injury of other and unspecified intrathoracic organs
0.774 0.226 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.772 0.227 0.000
N21.0 Calculus in bladder
0.772 0.228 0.000
M80-M85 Disorders of bone density and structure
0.771 0.229 0.000
S32 Fracture of lumbar spine and pelvis
0.770 0.230 0.000
M94 Other disorders of cartilage
0.769 0.231 0.000
C23 Malignant neoplasm of gallbladder
0.767 0.233 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.764 0.236 0.000
J81 Pulmonary oedema
0.761 0.239 0.000
B02 Zoster [herpes zoster]
0.760 0.239 0.000
B35-B49 Mycoses
0.758 0.242 0.000
N25-N29 Other disorders of kidney and ureter
0.758 0.242 0.000
C67.5 Bladder neck
0.755 0.244 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.756 0.244 0.000
E20-E35 Disorders of other endocrine glands
0.755 0.245 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.755 0.245 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.754 0.246 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.751 0.249 0.000
T92 Sequelae of injuries of upper limb
0.751 0.249 0.000
M05-M14 Inflammatory polyarthropathies
0.751 0.249 0.000
M47 Spondylosis
0.750 0.250 0.000
C34 Malignant neoplasm of bronchus and lung
0.749 0.251 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.745 0.255 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.745 0.255 0.000
A41 Other septicaemia
0.744 0.256 0.000
N30.9 Cystitis, unspecified
0.744 0.256 0.000
N34 Urethritis and urethral syndrome
0.743 0.257 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.743 0.257 0.000
S10-S19 Injuries to the neck
0.742 0.258 0.000
C17 Malignant neoplasm of small intestine
0.742 0.258 0.000
D68 Other coagulation defects
0.741 0.259 0.000
E10-E14 Diabetes mellitus
0.739 0.260 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.737 0.263 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.737 0.263 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.735 0.265 0.000
N64.4 Mastodynia
0.734 0.266 0.000
Q60-Q64 Congenital malformations of the urinary system
0.733 0.267 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.733 0.267 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.732 0.268 0.000
N30.3 Trigonitis
0.730 0.270 0.000
F20.0 Paranoid schizophrenia
0.730 0.270 0.000
M15-M19 Arthrosis
0.730 0.270 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.727 0.272 0.000
C48.2 Peritoneum, unspecified
0.727 0.273 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.727 0.273 0.000
A80-A89 Viral infections of the central nervous system
0.726 0.273 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.727 0.273 0.000
B65-B83 Helminthiases
0.726 0.274 0.000
B01 Varicella [chickenpox]
0.724 0.276 0.000
C67.1 Dome of bladder
0.721 0.279 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.721 0.279 0.000
F20.9 Schizophrenia, unspecified
0.721 0.279 0.000
C18.5 Splenic flexure
0.721 0.279 0.000
Z72 Problems related to lifestyle
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C21 Malignant neoplasm of anus and anal canal
0.717 0.283 0.000
C18.8 Overlapping lesion of colon
0.716 0.284 0.000
C18.1 Appendix
0.716 0.284 0.000
A41.9 Septicaemia, unspecified
0.716 0.284 0.000
F23 Acute and transient psychotic disorders
0.714 0.285 0.000
Q66 Congenital deformities of feet
0.714 0.286 0.000
N99-N99 Other disorders of the genitourinary system
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.714 0.286 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.713 0.287 0.000
G71 Primary disorders of muscles
0.713 0.287 0.000
N37 Urethral disorders in diseases classified elsewhere
0.713 0.287 0.000
N33 Bladder disorders in diseases classified elsewhere
0.713 0.287 0.000
Z72.1 Alcohol use
0.712 0.288 0.000
M92 Other juvenile osteochondrosis
0.712 0.288 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.711 0.288 0.000
C66 Malignant neoplasm of ureter
0.711 0.288 0.000
C65 Malignant neoplasm of renal pelvis
0.711 0.288 0.000
E11 Non-insulin-dependent diabetes mellitus
0.711 0.289 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.711 0.289 0.000
F25 Schizoaffective disorders
0.709 0.291 0.000
G35 Multiple sclerosis
0.709 0.291 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
A15-A19 Tuberculosis
0.708 0.292 0.000
S22.40 Multiple fractures of ribs (closed)
0.708 0.292 0.000
H60-H62 Diseases of external ear
0.708 0.292 0.000
N63 Unspecified lump in breast
0.708 0.292 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.705 0.295 0.000
G24 Dystonia
0.705 0.295 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.704 0.295 0.000
N30.1 Interstitial cystitis (chronic)
0.704 0.296 0.000
C67.8 Overlapping lesion of bladder
0.704 0.296 0.000
C67.7 Urachus
0.704 0.296 0.000
C67.0 Trigone of bladder
0.704 0.296 0.000
C25.0 Head of pancreas
0.703 0.297 0.000
N30.4 Irradiation cystitis
0.702 0.298 0.000
B15-B19 Viral hepatitis
0.701 0.299 0.000
N03 Chronic nephritic syndrome
0.701 0.299 0.000
A40 Streptococcal septicaemia
0.700 0.300 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.700 0.300 0.000
Q35-Q37 Cleft lip and cleft palate
0.700 0.300 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.700 0.300 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.700 0.300 0.000
B00.4 Herpesviral encephalitis
0.698 0.302 0.000
N60.0 Solitary cyst of breast
0.698 0.302 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.696 0.304 0.000
B25 Cytomegaloviral disease
0.695 0.305 0.000
S50-S59 Injuries to the elbow and forearm
0.693 0.307 0.000
Y40 Systemic antibiotics
0.692 0.308 0.000
L40-L45 Papulosquamous disorders
0.692 0.308 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.692 0.308 0.000
J02 Acute pharyngitis
0.692 0.308 0.000
N64.3 Galactorrhoea not associated with childbirth
0.691 0.309 0.000
N64.2 Atrophy of breast
0.691 0.309 0.000
N64.0 Fissure and fistula of nipple
0.691 0.309 0.000
Y88 Sequelae of surgical and medical care as external cause
0.690 0.310 0.000
T91 Sequelae of injuries of neck and trunk
0.689 0.311 0.000
E40-E46 Malnutrition
0.689 0.311 0.000
B06 Rubella [German measles]
0.689 0.311 0.000
B05 Measles
0.689 0.311 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.689 0.311 0.000
B04 Monkeypox
0.689 0.311 0.000
B03 Smallpox
0.689 0.311 0.000
D46 Myelodysplastic syndromes
0.686 0.314 0.000
C67.6 Ureteric orifice
0.685 0.315 0.000
N39.2 Orthostatic proteinuria, unspecified
0.685 0.315 0.000
N39.1 Persistent proteinuria, unspecified
0.685 0.315 0.000
M94.8 Other specified disorders of cartilage
0.685 0.315 0.000
M47.9 Spondylosis, unspecified
0.685 0.315 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.684 0.316 0.000
C46 Kaposi's sarcoma
0.684 0.316 0.000
D69 Purpura and other haemorrhagic conditions
0.684 0.316 0.000
N17.8 Other acute renal failure
0.683 0.317 0.000
N17.2 Acute renal failure with medullary necrosis
0.683 0.317 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.683 0.317 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.683 0.317 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.683 0.317 0.000
E11.3 With ophthalmic complications
0.682 0.318 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.681 0.319 0.000
N36.0 Urethral fistula
0.681 0.319 0.000
H80-H83 Diseases of inner ear
0.681 0.319 0.000
B95-B98 Bacterial, viral and other infectious agents
0.680 0.320 0.000
S90-S99 Injuries to the ankle and foot
0.680 0.320 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.679 0.321 0.000
N64.1 Fat necrosis of breast
0.679 0.321 0.000
B00.5 Herpesviral ocular disease
0.678 0.322 0.000
M20-M25 Other joint disorders
0.678 0.322 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.675 0.325 0.000
C49.9 Connective and soft tissue, unspecified
0.674 0.326 0.000
C15.4 Middle third of oesophagus
0.674 0.326 0.000
C12 Malignant neoplasm of pyriform sinus
0.674 0.326 0.000
C05 Malignant neoplasm of palate
0.673 0.327 0.000
W50-W64 Exposure to animate mechanical forces
0.670 0.329 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.668 0.332 0.000
C22.1 Intrahepatic bile duct carcinoma
0.668 0.332 0.000
C49.5 Connective and soft tissue of pelvis
0.667 0.332 0.000
S22.1 Multiple fractures of thoracic spine
0.667 0.332 0.000
T33-T35 Frostbite
0.666 0.334 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.666 0.334 0.000
T00-T07 Injuries involving multiple body regions
0.666 0.334 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.666 0.334 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.666 0.334 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.665 0.335 0.000
M19 Other arthrosis
0.665 0.335 0.000
N39.4 Other specified urinary incontinence
0.665 0.335 0.000
G23 Other degenerative diseases of basal ganglia
0.664 0.336 0.000
G21 Secondary Parkinsonism
0.664 0.336 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.664 0.336 0.000
G22 Parkinsonism in diseases classified elsewhere
0.664 0.336 0.000
Q82 Other congenital malformations of skin
0.664 0.336 0.000
M00-M03 Infectious arthropathies
0.663 0.336 0.000
N39.9 Disorder of urinary system, unspecified
0.661 0.339 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.661 0.339 0.000
C48.0 Retroperitoneum
0.661 0.339 0.000
C15.5 Lower third of oesophagus
0.661 0.339 0.000
Z73 Problems related to life-management difficulty
0.660 0.340 0.000
F80-F89 Disorders of psychological development
0.660 0.340 0.000
D55-D59 Haemolytic anaemias
0.659 0.340 0.000
C71 Malignant neoplasm of brain
0.659 0.341 0.000
L40 Psoriasis
0.659 0.341 0.000
G25 Other extrapyramidal and movement disorders
0.658 0.342 0.000
Q85 Phakomatoses, not elsewhere classified
0.658 0.342 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.657 0.343 0.000
Q76 Congenital malformations of spine and bony thorax
0.657 0.343 0.000
B35 Dermatophytosis
0.655 0.345 0.000
C24.1 Ampulla of Vater
0.655 0.345 0.000
B33 Other viral diseases, not elsewhere classified
0.655 0.345 0.000
B30 Viral conjunctivitis
0.655 0.345 0.000
B27 Infectious mononucleosis
0.655 0.345 0.000
B26 Mumps
0.655 0.345 0.000
Q51 Congenital malformations of uterus and cervix
0.654 0.345 0.000
G95 Other diseases of spinal cord
0.654 0.346 0.000
C45.9 Mesothelioma, unspecified
0.654 0.346 0.000
S22.2 Fracture of sternum
0.654 0.346 0.000
N36.8 Other specified disorders of urethra
0.653 0.347 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.652 0.348 0.000
V80-V89 Other land transport accidents
0.652 0.348 0.000
G90 Disorders of autonomic nervous system
0.652 0.348 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.651 0.348 0.000
Q05 Spina bifida
0.651 0.349 0.000
M62 Other disorders of muscle
0.650 0.350 0.000
D43.2 Brain, unspecified
0.650 0.350 0.000
M25 Other joint disorders, not elsewhere classified
0.650 0.350 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.650 0.350 0.000
T79-T79 Certain early complications of trauma
0.650 0.350 0.000
Y35-Y36 Legal intervention and operations of war
0.650 0.350 0.000
Y10-Y34 Event of undetermined intent
0.650 0.350 0.000
Y00-Y09 Assault
0.650 0.350 0.000
X85-X99 Assault
0.650 0.350 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.650 0.350 0.000
X30-X39 Exposure to forces of nature
0.650 0.350 0.000
X10-X19 Contact with heat and hot substances
0.650 0.350 0.000
X00-X09 Exposure to smoke, fire and flames
0.650 0.350 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.650 0.350 0.000
W75-W84 Other accidental threats to breathing
0.650 0.350 0.000
W65-W74 Accidental drowning and submersion
0.650 0.350 0.000
V98-V99 Other and unspecified transport accidents
0.650 0.350 0.000
V95-V97 Air and space transport accidents
0.650 0.350 0.000
V90-V94 Water transport accidents
0.650 0.350 0.000
V70-V79 Bus occupant injured in transport accident
0.650 0.350 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.650 0.350 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.650 0.350 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.650 0.350 0.000
V01-V09 Pedestrian injured in transport accident
0.650 0.350 0.000
B34.8 Other viral infections of unspecified site
0.648 0.352 0.000
S37 Injury of urinary and pelvic organs
0.647 0.353 0.000
D43.0 Brain, supratentorial
0.646 0.354 0.000
V20-V29 Motorcycle rider injured in transport accident
0.646 0.354 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.646 0.354 0.000
M93 Other osteochondropathies
0.646 0.354 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.645 0.355 0.000
S26 Injury of heart
0.645 0.355 0.000
S25 Injury of blood vessels of thorax
0.645 0.355 0.000
S24 Injury of nerves and spinal cord at thorax level
0.645 0.355 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.645 0.355 0.000
S21 Open wound of thorax
0.645 0.355 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.644 0.356 0.000
V40-V49 Car occupant injured in transport accident
0.644 0.356 0.000
S72 Fracture of femur
0.644 0.356 0.000
C24.0 Extrahepatic bile duct
0.644 0.356 0.000
G71.0 Muscular dystrophy
0.644 0.356 0.000
L50-L54 Urticaria and erythema
0.643 0.357 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.642 0.357 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.642 0.357 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.642 0.357 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.641 0.359 0.000
X20-X29 Contact with venomous animals and plants
0.640 0.360 0.000
D75 Other diseases of blood and blood-forming organs
0.638 0.362 0.000
M24 Other specific joint derangements
0.637 0.363 0.000
C43 Malignant melanoma of skin
0.636 0.364 0.000
C22.0 Liver cell carcinoma
0.636 0.364 0.000
M82 Osteoporosis in diseases classified elsewhere
0.635 0.365 0.000
D60-D64 Aplastic and other anaemias
0.635 0.365 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.634 0.366 0.000
D45 Polycythaemia vera
0.634 0.366 0.000
A46 Erysipelas
0.634 0.366 0.000
S27.2 Traumatic heamopneumothorax
0.634 0.366 0.000
T93 Sequelae of injuries of lower limb
0.633 0.367 0.000
C25.9 Pancreas, unspecified
0.633 0.367 0.000
M14 Arthropathies in other diseases classified elsewhere
0.633 0.367 0.000
J01 Acute sinusitis
0.632 0.368 0.000
T66-T78 Other and unspecified effects of external causes
0.631 0.369 0.000
L40.9 Psoriasis, unspecified
0.630 0.370 0.000
D68.2 Hereditary deficiency of other clotting factors
0.630 0.370 0.000
F99-F99 Unspecified mental disorder
0.630 0.370 0.000
B00.1 Herpesviral vesicular dermatitis
0.630 0.370 0.000
C16.9 Stomach, unspecified
0.630 0.370 0.000
G30-G32 Other degenerative diseases of the nervous system
0.629 0.371 0.000
M40-M43 Deforming dorsopathies
0.629 0.371 0.000
Q24 Other congenital malformations of heart
0.628 0.372 0.000
Z04 Examination and observation for other reasons
0.628 0.372 0.000
S70 Superficial injury of hip and thigh
0.627 0.373 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.627 0.373 0.000
G82 Paraplegia and tetraplegia
0.627 0.373 0.000
C45.0 Mesothelioma of pleura
0.626 0.373 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.626 0.374 0.000
F70-F79 Mental retardation
0.626 0.374 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.625 0.375 0.000
Y98 Lifestyle-related condition
0.625 0.375 0.000
Y97 Environmental-pollution-related condition
0.625 0.375 0.000
Y96 Work-related condition
0.625 0.375 0.000
M84 Disorders of continuity of bone
0.625 0.375 0.000
C34.1 Upper lobe, bronchus or lung
0.625 0.375 0.000
S22.9 Fracture of bony thorax, part unspecified
0.624 0.375 0.000
S22.8 Fracture of other parts of bony thorax
0.624 0.375 0.000
S22.5 Flail chest
0.624 0.375 0.000
Q66.8 Other congenital deformities of feet
0.624 0.376 0.000
S27.0 Traumatic pneumothorax
0.624 0.376 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.623 0.377 0.000
Y86 Sequelae of other accidents
0.623 0.377 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.622 0.378 0.000
H61 Other disorders of external ear
0.621 0.379 0.000
E29 Testicular dysfunction
0.621 0.379 0.000
Z75 Problems related to medical facilities and other health care
0.620 0.380 0.000
F30-F39 Mood [affective] disorders
0.620 0.380 0.000
M19.94 Arthrosis, unspecified (Hand)
0.619 0.381 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.618 0.381 0.000
M19.9 Arthrosis, unspecified
0.618 0.382 0.000
N02 Recurrent and persistent haematuria
0.618 0.382 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.617 0.383 0.000
B02.9 Zoster without complication
0.617 0.383 0.000
D68.8 Other specified coagulation defects
0.615 0.385 0.000
Y85 Sequelae of transport accidents
0.615 0.385 0.000
A48 Other bacterial diseases, not elsewhere classified
0.614 0.386 0.000
A44 Bartonellosis
0.614 0.386 0.000
A43 Nocardiosis
0.614 0.386 0.000
A42 Actinomycosis
0.614 0.386 0.000
A39 Meningococcal infection
0.614 0.386 0.000
A37 Whooping cough
0.614 0.386 0.000
A36 Diphtheria
0.614 0.386 0.000
A32 Listeriosis
0.614 0.386 0.000
A31 Infection due to other mycobacteria
0.614 0.386 0.000
A30 Leprosy [Hansen's disease]
0.614 0.386 0.000
A38 Scarlet fever
0.614 0.386 0.000
A35 Other tetanus
0.614 0.386 0.000
A34 Obstetrical tetanus
0.614 0.386 0.000
A33 Tetanus neonatorum
0.614 0.386 0.000
M11 Other crystal arthropathies
0.613 0.387 0.000
F22 Persistent delusional disorders
0.613 0.387 0.000
G96 Other disorders of central nervous system
0.612 0.388 0.000
T98 Sequelae of other and unspecified effects of external causes
0.611 0.388 0.000
T95 Sequelae of burns, corrosions and frostbite
0.611 0.388 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.611 0.388 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.611 0.388 0.000
C34.9 Bronchus or lung, unspecified
0.611 0.389 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.611 0.389 0.000
J80 Adult respiratory distress syndrome
0.610 0.390 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.609 0.390 0.000
F25.9 Schizoaffective disorder, unspecified
0.609 0.391 0.000
B34.4 Papovirus infection, unspecified
0.609 0.391 0.000
B34.3 Parvovirus infection, unspecified
0.609 0.391 0.000
B34.2 Coronavirus infection, unspecified
0.609 0.391 0.000
B34.1 Enterovirus infection, unspecified
0.609 0.391 0.000
B34.0 Adenovirus infection, unspecified
0.609 0.391 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.609 0.391 0.000
S36 Injury of intra-abdominal organs
0.609 0.391 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.609 0.391 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.609 0.391 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.609 0.391 0.000
S31 Open wound of abdomen, lower back and pelvis
0.609 0.391 0.000
N60.3 Fibrosclerosis of breast
0.609 0.391 0.000
F28 Other nonorganic psychotic disorders
0.609 0.391 0.000
F24 Induced delusional disorder
0.609 0.391 0.000
F21 Schizotypal disorder
0.609 0.391 0.000
S22.3 Fracture of rib
0.609 0.391 0.000
C15.9 Oesophagus, unspecified
0.608 0.392 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.608 0.392 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.607 0.393 0.000
B08.1 Molluscum contagiosum
0.607 0.393 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.607 0.393 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.607 0.393 0.000
C31 Malignant neoplasm of accessory sinuses
0.607 0.393 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.607 0.393 0.000
C37 Malignant neoplasm of thymus
0.607 0.393 0.000
C33 Malignant neoplasm of trachea
0.607 0.393 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.607 0.393 0.000
F60-F69 Disorders of adult personality and behaviour
0.606 0.393 0.000
S32.0 Fracture of lumbar vertebra
0.606 0.394 0.000
E11.6 With other specified complications
0.606 0.394 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.606 0.394 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.605 0.394 0.000
N06 Isolated proteinuria with specified morphological lesion
0.605 0.394 0.000
N01 Rapidly progressive nephritic syndrome
0.605 0.394 0.000
N00 Acute nephritic syndrome
0.605 0.394 0.000
J06.8 Other acute upper respiratory infections of multiple sites
0.605 0.395 0.000
J06.0 Acute laryngopharyngitis
0.605 0.395 0.000
D48.0 Bone and articular cartilage
0.605 0.395 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.604 0.396 0.000
B00.9 Herpesviral infection, unspecified
0.603 0.397 0.000
B00.8 Other forms of herpesviral infection
0.603 0.397 0.000
B00.7 Disseminated herpesviral disease
0.603 0.397 0.000
B00.3 Herpesviral meningitis
0.603 0.397 0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis
0.603 0.397 0.000
B00.0 Eczema herpeticum
0.603 0.397 0.000
J04 Acute laryngitis and tracheitis
0.602 0.398 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.602 0.398 0.000
Q78 Other osteochondrodysplasias
0.602 0.398 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.602 0.398 0.000
Q75 Other congenital malformations of skull and face bones
0.602 0.398 0.000
Q74 Other congenital malformations of limb(s)
0.602 0.398 0.000
Q73 Reduction defects of unspecified limb
0.602 0.398 0.000
Q72 Reduction defects of lower limb
0.602 0.398 0.000
Q71 Reduction defects of upper limb
0.602 0.398 0.000
Q70 Syndactyly
0.602 0.398 0.000
Q69 Polydactyly
0.602 0.398 0.000
Q68 Other congenital musculoskeletal deformities
0.602 0.398 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.602 0.398 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.602 0.398 0.000
E27 Other disorders of adrenal gland
0.602 0.398 0.000
N60.8 Other benign mammary dysplasias
0.601 0.399 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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