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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4921542
log Bayes Factor = 5.71395
Chromosome 8   position 17,205,577  (GRCh37) Explore rs4921542 on Ensembl!
Variant rs4921542 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
E10-E14 Diabetes mellitus
0.971 0.029 0.000
S50-S59 Injuries to the elbow and forearm
0.969 0.031 0.000
O60-O75 Complications of labour and delivery
0.965 0.035 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.964 0.036 0.000
Chapter XX External causes of morbidity and mortality
0.958 0.042 0.000
Chapter XIV Diseases of the genitourinary system
0.957 0.043 0.000
S80-S89 Injuries to the knee and lower leg
0.956 0.044 0.000
E65-E68 Obesity and other hyperalimentation
0.954 0.046 0.000
E10 Insulin-dependent diabetes mellitus
0.948 0.052 0.000
S90-S99 Injuries to the ankle and foot
0.942 0.058 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.937 0.063 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.936 0.064 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.930 0.070 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.929 0.071 0.000
S82 Fracture of lower leg, including ankle
0.926 0.074 0.000
E66 Obesity
0.925 0.075 0.000
N17-N19 Renal failure
0.924 0.076 0.000
N00-N08 Glomerular diseases
0.920 0.080 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.919 0.081 0.000
E66.8 Other obesity
0.918 0.082 0.000
S40-S49 Injuries to the shoulder and upper arm
0.914 0.086 0.000
Chapter VII Diseases of the eye and adnexa
0.910 0.090 0.000
S52 Fracture of forearm
0.907 0.093 0.000
Y95 Nosocomial condition
0.907 0.093 0.000
N18 Chronic renal failure
0.903 0.097 0.000
E10.9 Without complications
0.897 0.103 0.000
S20-S29 Injuries to the thorax
0.895 0.105 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.876 0.124 0.000
G90-G99 Other disorders of the nervous system
0.875 0.125 0.000
S52.6 Fracture of lower end of both ulna and radius
0.874 0.126 0.000
G20-G26 Extrapyramidal and movement disorders
0.868 0.132 0.000
Chapter I Certain infectious and parasitic diseases
0.866 0.134 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.865 0.135 0.000
Chapter VIII Diseases of the ear and mastoid process
0.859 0.141 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.858 0.142 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.857 0.143 0.000
H55-H59 Other disorders of eye and adnexa
0.854 0.146 0.000
Chapter V Mental and behavioural disorders
0.852 0.148 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.850 0.150 0.000
B95-B98 Bacterial, viral and other infectious agents
0.850 0.150 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.845 0.155 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.845 0.155 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.845 0.155 0.000
G40-G47 Episodic and paroxysmal disorders
0.843 0.157 0.000
N18.5 Chronic kidney disease, stage 5
0.841 0.159 0.000
G62 Other polyneuropathies
0.841 0.159 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.838 0.162 0.000
S82.1 Fracture of upper end of tibia
0.834 0.166 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.834 0.166 0.000
N18.4 Chronic kidney disease, stage 4
0.832 0.168 0.000
S82.3 Fracture of lower end of tibia
0.830 0.170 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.829 0.171 0.000
O00-O08 Pregnancy with abortive outcome
0.828 0.172 0.000
E13 Other specified diabetes mellitus
0.824 0.176 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.821 0.179 0.000
E00-E07 Disorders of thyroid gland
0.821 0.179 0.000
S91 Open wound of ankle and foot
0.820 0.180 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.819 0.181 0.000
E10.1 With ketoacidosis
0.818 0.182 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.817 0.183 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.814 0.186 0.000
N03 Chronic nephritic syndrome
0.812 0.188 0.000
S50 Superficial injury of forearm
0.810 0.190 0.000
S70-S79 Injuries to the hip and thigh
0.809 0.191 0.000
T91 Sequelae of injuries of neck and trunk
0.807 0.193 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.805 0.195 0.000
G70-G73 Diseases of myoneural junction and muscle
0.803 0.197 0.000
N99-N99 Other disorders of the genitourinary system
0.802 0.198 0.000
N02 Recurrent and persistent haematuria
0.800 0.200 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.800 0.200 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.799 0.201 0.000
S51 Open wound of forearm
0.798 0.202 0.000
F30-F39 Mood [affective] disorders
0.796 0.204 0.000
G30-G32 Other degenerative diseases of the nervous system
0.796 0.204 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.796 0.204 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.796 0.204 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.790 0.210 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.789 0.211 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.788 0.212 0.000
O30 Multiple gestation
0.787 0.213 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.784 0.216 0.000
T93 Sequelae of injuries of lower limb
0.783 0.217 0.000
N10-N16 Renal tubulo-interstitial diseases
0.783 0.217 0.000
W50-W64 Exposure to animate mechanical forces
0.783 0.217 0.000
S92 Fracture of foot, except ankle
0.782 0.218 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.782 0.218 0.000
S20 Superficial injury of thorax
0.781 0.218 0.000
S80 Superficial injury of lower leg
0.780 0.220 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.777 0.223 0.000
E20-E35 Disorders of other endocrine glands
0.775 0.225 0.000
S40 Superficial injury of shoulder and upper arm
0.774 0.225 0.000
N17 Acute renal failure
0.774 0.226 0.000
H55 Nystagmus and other irregular eye movements
0.773 0.227 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.771 0.229 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.770 0.230 0.000
G62.9 Polyneuropathy, unspecified
0.770 0.230 0.000
O04 Medical abortion
0.769 0.231 0.000
S82.10 Fracture of upper end of tibia (closed)
0.768 0.232 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.767 0.233 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.767 0.233 0.000
N05 Unspecified nephritic syndrome
0.766 0.234 0.000
H52 Disorders of refraction and accommodation
0.765 0.235 0.000
E11 Non-insulin-dependent diabetes mellitus
0.765 0.235 0.000
N18.9 Chronic renal failure, unspecified
0.764 0.236 0.000
O71 Other obstetric trauma
0.763 0.237 0.000
S82.30 Fracture of lower end of tibia (closed)
0.761 0.239 0.000
H18 Other disorders of cornea
0.760 0.240 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.760 0.240 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.754 0.246 0.000
G24 Dystonia
0.753 0.247 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.752 0.248 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.752 0.248 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.752 0.248 0.000
S90 Superficial injury of ankle and foot
0.750 0.250 0.000
T90 Sequelae of injuries of head
0.749 0.251 0.000
H60-H62 Diseases of external ear
0.749 0.251 0.000
S82.0 Fracture of patella
0.748 0.252 0.000
E10.4 With neurological complications
0.748 0.252 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.746 0.254 0.000
O40 Polyhydramnios
0.745 0.255 0.000
N73 Other female pelvic inflammatory diseases
0.744 0.256 0.000
G82 Paraplegia and tetraplegia
0.744 0.256 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.744 0.256 0.000
N18.0 End-stage renal disease
0.743 0.257 0.000
S52.1 Fracture of upper end of radius
0.742 0.258 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.742 0.258 0.000
O85-O92 Complications predominantly related to the puerperium
0.742 0.258 0.000
S10-S19 Injuries to the neck
0.738 0.262 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.738 0.262 0.000
V20-V29 Motorcycle rider injured in transport accident
0.736 0.264 0.000
N03.9 Unspecified
0.735 0.265 0.000
S82.4 Fracture of fibula alone
0.734 0.266 0.000
S00-S09 Injuries to the head
0.733 0.267 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.732 0.268 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.732 0.268 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.732 0.268 0.000
S82.6 Fracture of lateral malleolus
0.732 0.268 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.731 0.269 0.000
Chapter XXII Codes for special purposes
0.731 0.269 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.730 0.270 0.000
G90 Disorders of autonomic nervous system
0.729 0.271 0.000
O04.9 Complete or unspecified, without complication
0.728 0.272 0.000
O62 Abnormalities of forces of labour
0.726 0.274 0.000
G40 Epilepsy
0.726 0.274 0.000
T42.4 Benzodiazepines
0.725 0.275 0.000
N84 Polyp of female genital tract
0.724 0.276 0.000
S20.2 Contusion of thorax
0.723 0.277 0.000
S89 Other and unspecified injuries of lower leg
0.720 0.280 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.720 0.280 0.000
S51.0 Open wound of elbow
0.720 0.280 0.000
T79-T79 Certain early complications of trauma
0.719 0.280 0.000
E10.3 With ophthalmic complications
0.719 0.281 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.719 0.281 0.000
O36 Maternal care for other known or suspected foetal problems
0.719 0.281 0.000
N87 Dysplasia of cervix uteri
0.719 0.281 0.000
G95 Other diseases of spinal cord
0.718 0.281 0.000
E13.9 Without complications
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F41 Other anxiety disorders
0.717 0.283 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.714 0.286 0.000
H21 Other disorders of iris and ciliary body
0.711 0.289 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.711 0.289 0.000
T43.2 Other and unspecified antidepressants
0.710 0.290 0.000
S86 Injury of muscle and tendon at lower leg level
0.710 0.290 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.709 0.291 0.000
G44 Other headache syndromes
0.709 0.291 0.000
T92 Sequelae of injuries of upper limb
0.708 0.292 0.000
H57 Other disorders of eye and adnexa
0.707 0.293 0.000
F31 Bipolar affective disorder
0.704 0.296 0.000
G61 Inflammatory polyneuropathy
0.703 0.297 0.000
N84.0 Polyp of corpus uteri
0.703 0.297 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.702 0.298 0.000
O46.9 Antepartum haemorrhage, unspecified
0.702 0.298 0.000
S99 Other and unspecified injuries of ankle and foot
0.701 0.299 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.700 0.300 0.000
F41.2 Mixed anxiety and depressive disorder
0.699 0.301 0.000
H65-H75 Diseases of middle ear and mastoid
0.699 0.301 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.698 0.302 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.698 0.302 0.000
S50.9 Superficial injury of forearm, unspecified
0.697 0.303 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.696 0.304 0.000
E12 Malnutrition-related diabetes mellitus
0.696 0.304 0.000
S91.3 Open wound of other parts of foot
0.695 0.305 0.000
S59 Other and unspecified injuries of forearm
0.695 0.305 0.000
S58 Traumatic amputation of forearm
0.695 0.305 0.000
S57 Crushing injury of forearm
0.695 0.305 0.000
S56 Injury of muscle and tendon at forearm level
0.695 0.305 0.000
S55 Injury of blood vessels at forearm level
0.695 0.305 0.000
S54 Injury of nerves at forearm level
0.695 0.305 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.695 0.305 0.000
H43-H45 Disorders of vitreous body and globe
0.695 0.305 0.000
O44 Placenta praevia
0.693 0.307 0.000
S71 Open wound of hip and thigh
0.693 0.307 0.000
E16 Other disorders of pancreatic internal secretion
0.692 0.308 0.000
N72 Inflammatory disease of cervix uteri
0.692 0.308 0.000
G96 Other disorders of central nervous system
0.692 0.308 0.000
O74 Complications of anaesthesia during labour and delivery
0.692 0.308 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.692 0.308 0.000
O61 Failed induction of labour
0.692 0.308 0.000
O60 Preterm delivery
0.692 0.308 0.000
N73.6 Female pelvic peritoneal adhesions
0.691 0.309 0.000
W20-W49 Exposure to inanimate mechanical forces
0.691 0.309 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.691 0.309 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.691 0.309 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.691 0.309 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.691 0.309 0.000
T36 Poisoning by systemic antibiotics
0.691 0.309 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.691 0.309 0.000
N04 Nephrotic syndrome
0.690 0.310 0.000
N71 Inflammatory disease of uterus, except cervix
0.689 0.311 0.000
O63 Long labour
0.689 0.311 0.000
O75.0 Maternal distress during labour and delivery
0.688 0.312 0.000
Y35-Y36 Legal intervention and operations of war
0.687 0.313 0.000
Y10-Y34 Event of undetermined intent
0.687 0.313 0.000
Y00-Y09 Assault
0.687 0.313 0.000
X85-X99 Assault
0.687 0.313 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.687 0.313 0.000
X50-X57 Overexertion, travel and privation
0.687 0.313 0.000
X30-X39 Exposure to forces of nature
0.687 0.313 0.000
X20-X29 Contact with venomous animals and plants
0.687 0.313 0.000
X10-X19 Contact with heat and hot substances
0.687 0.313 0.000
X00-X09 Exposure to smoke, fire and flames
0.687 0.313 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.313 0.000
W75-W84 Other accidental threats to breathing
0.687 0.313 0.000
W65-W74 Accidental drowning and submersion
0.687 0.313 0.000
V98-V99 Other and unspecified transport accidents
0.687 0.313 0.000
V95-V97 Air and space transport accidents
0.687 0.313 0.000
V90-V94 Water transport accidents
0.687 0.313 0.000
V70-V79 Bus occupant injured in transport accident
0.687 0.313 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.687 0.313 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.687 0.313 0.000
V40-V49 Car occupant injured in transport accident
0.687 0.313 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.687 0.313 0.000
V01-V09 Pedestrian injured in transport accident
0.687 0.313 0.000
N80 Endometriosis
0.686 0.314 0.000
S88 Traumatic amputation of lower leg
0.686 0.314 0.000
S87 Crushing injury of lower leg
0.686 0.314 0.000
S85 Injury of blood vessels at lower leg level
0.686 0.314 0.000
S84 Injury of nerves at lower leg level
0.686 0.314 0.000
S41 Open wound of shoulder and upper arm
0.685 0.315 0.000
N95 Menopausal and other perimenopausal disorders
0.685 0.315 0.000
E67 Other hyperalimentation
0.684 0.316 0.000
E68 Sequelae of hyperalimentation
0.684 0.316 0.000
E65 Localised adiposity
0.684 0.316 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.684 0.316 0.000
S52.2 Fracture of shaft of ulna
0.683 0.317 0.000
E10.8 With unspecified complications
0.679 0.320 0.000
E10.7 With multiple complications
0.679 0.320 0.000
E10.6 With other specified complications
0.679 0.320 0.000
E10.2 With renal complications
0.679 0.320 0.000
E10.0 With coma
0.679 0.320 0.000
N02.8 Other
0.679 0.321 0.000
O30.0 Twin pregnancy
0.678 0.322 0.000
O73 Retained placenta and membranes, without haemorrhage
0.678 0.322 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.677 0.323 0.000
S92.3 Fracture of metatarsal bone
0.677 0.323 0.000
E11.4 With neurological complications
0.677 0.323 0.000
O43 Placental disorders
0.676 0.324 0.000
S98 Traumatic amputation of ankle and foot
0.675 0.325 0.000
S97 Crushing injury of ankle and foot
0.675 0.325 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.675 0.325 0.000
S95 Injury of blood vessels at ankle and foot level
0.675 0.325 0.000
S94 Injury of nerves at ankle and foot level
0.675 0.325 0.000
Q80-Q89 Other congenital malformations
0.675 0.325 0.000
Q50-Q56 Congenital malformations of genital organs
0.675 0.325 0.000
S27 Injury of other and unspecified intrathoracic organs
0.675 0.325 0.000
G93 Other disorders of brain
0.674 0.325 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.674 0.326 0.000
S82.8 Fractures of other parts of lower leg
0.673 0.327 0.000
F32 Depressive episode
0.673 0.327 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.673 0.327 0.000
O45 Premature separation of placenta [abruptio placentae]
0.672 0.328 0.000
O33 Maternal care for known or suspected disproportion
0.672 0.328 0.000
O31 Complications specific to multiple gestation
0.672 0.328 0.000
T98 Sequelae of other and unspecified effects of external causes
0.671 0.329 0.000
T95 Sequelae of burns, corrosions and frostbite
0.671 0.329 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.671 0.329 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.671 0.329 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.671 0.329 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.670 0.330 0.000
G24.9 Dystonia, unspecified
0.670 0.330 0.000
E06 Thyroiditis
0.670 0.330 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.669 0.331 0.000
G63.2 Diabetic polyneuropathy
0.668 0.332 0.000
G25 Other extrapyramidal and movement disorders
0.668 0.332 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.668 0.332 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.667 0.333 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.667 0.333 0.000
Y98 Lifestyle-related condition
0.667 0.333 0.000
Y97 Environmental-pollution-related condition
0.667 0.333 0.000
Y96 Work-related condition
0.667 0.333 0.000
G64 Other disorders of peripheral nervous system
0.666 0.334 0.000
E50-E64 Other nutritional deficiencies
0.666 0.334 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.666 0.334 0.000
O42 Premature rupture of membranes
0.665 0.334 0.000
G70 Myasthenia gravis and other myoneural disorders
0.665 0.335 0.000
S82.9 Fracture of lower leg, part unspecified
0.664 0.336 0.000
S82.7 Multiple fractures of lower leg
0.664 0.336 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.663 0.337 0.000
E66.1 Drug-induced obesity
0.663 0.337 0.000
E66.0 Obesity due to excess calories
0.663 0.337 0.000
E04 Other non-toxic goitre
0.663 0.337 0.000
E10.5 With peripheral circulatory complications
0.662 0.338 0.000
N17.0 Acute renal failure with tubular necrosis
0.660 0.340 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.660 0.340 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.660 0.340 0.000
N06 Isolated proteinuria with specified morphological lesion
0.660 0.340 0.000
N01 Rapidly progressive nephritic syndrome
0.660 0.340 0.000
N00 Acute nephritic syndrome
0.660 0.340 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.660 0.340 0.000
G45.4 Transient global amnesia
0.659 0.341 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.659 0.341 0.000
S91.1 Open wound of toe(s) without damage to nail
0.658 0.342 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.658 0.342 0.000
V10-V19 Pedal cyclist injured in transport accident
0.656 0.344 0.000
H18.4 Corneal degeneration
0.656 0.344 0.000
H50 Other strabismus
0.656 0.344 0.000
S48 Traumatic amputation of shoulder and upper arm
0.655 0.345 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.655 0.345 0.000
S44 Injury of nerves at shoulder and upper arm level
0.655 0.345 0.000
S47 Crushing injury of shoulder and upper arm
0.655 0.345 0.000
O72 Postpartum haemorrhage
0.655 0.345 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.655 0.345 0.000
O41 Other disorders of amniotic fluid and membranes
0.654 0.345 0.000
H52.0 Hypermetropia
0.654 0.346 0.000
N80.1 Endometriosis of ovary
0.654 0.346 0.000
O70 Perineal laceration during delivery
0.654 0.346 0.000
H16 Keratitis
0.654 0.346 0.000
H65 Nonsuppurative otitis media
0.652 0.348 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.651 0.349 0.000
B99-B99 Other infectious diseases
0.651 0.349 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.651 0.349 0.000
S52.9 Fracture of forearm, part unspecified
0.650 0.349 0.000
S52.7 Multiple fractures of forearm
0.650 0.349 0.000
S52.4 Fracture of shafts of both ulna and radius
0.650 0.349 0.000
S52.3 Fracture of shaft of radius
0.650 0.349 0.000
O66 Other obstructed labour
0.650 0.350 0.000
N18.8 Other chronic renal failure
0.648 0.352 0.000
N18.1 Chronic kidney disease, stage 1
0.648 0.352 0.000
E11.3 With ophthalmic complications
0.648 0.352 0.000
B15-B19 Viral hepatitis
0.648 0.352 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.648 0.352 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.647 0.353 0.000
G60 Hereditary and idiopathic neuropathy
0.647 0.353 0.000
E07 Other disorders of thyroid
0.646 0.354 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.645 0.355 0.000
H61 Other disorders of external ear
0.643 0.357 0.000
V80-V89 Other land transport accidents
0.643 0.357 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.643 0.357 0.000
N95.0 Postmenopausal bleeding
0.642 0.358 0.000
S29 Other and unspecified injuries of thorax
0.641 0.358 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.641 0.358 0.000
S26 Injury of heart
0.641 0.358 0.000
S25 Injury of blood vessels of thorax
0.641 0.358 0.000
S24 Injury of nerves and spinal cord at thorax level
0.641 0.358 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.641 0.358 0.000
S21 Open wound of thorax
0.641 0.358 0.000
G45.3 Amaurosis fugax
0.641 0.359 0.000
O75.8 Other specified complications of labour and delivery
0.640 0.360 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.640 0.360 0.000
N02.9 Unspecified
0.640 0.360 0.000
S43.0 Dislocation of shoulder joint
0.639 0.361 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.639 0.361 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.638 0.361 0.000
N25-N29 Other disorders of kidney and ureter
0.638 0.362 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.637 0.363 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.636 0.363 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.636 0.364 0.000
S82.5 Fracture of medial malleolus
0.636 0.364 0.000
X60-X84 Intentional self-harm
0.635 0.365 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.635 0.365 0.000
F44 Dissociative [conversion] disorders
0.634 0.366 0.000
T91.3 Sequelae of injury of spinal cord
0.633 0.367 0.000
G20 Parkinson's disease
0.631 0.369 0.000
E40-E46 Malnutrition
0.631 0.369 0.000
H30-H36 Disorders of choroid and retina
0.631 0.369 0.000
N18.2 Chronic kidney disease, stage 2
0.631 0.369 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.630 0.370 0.000
G82.4 Spastic tetraplegia
0.630 0.370 0.000
N93 Other abnormal uterine and vaginal bleeding
0.630 0.370 0.000
G82.5 Tetraplegia, unspecified
0.629 0.371 0.000
S52.8 Fracture of other parts of forearm
0.629 0.371 0.000
T13 Other injuries of lower limb, level unspecified
0.629 0.371 0.000
H18.2 Other corneal oedema
0.629 0.371 0.000
G62.8 Other specified polyneuropathies
0.628 0.372 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.628 0.372 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.628 0.372 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.628 0.372 0.000
G92 Toxic encephalopathy
0.628 0.372 0.000
H52.3 Anisometropia and aniseikonia
0.628 0.372 0.000
E27 Other disorders of adrenal gland
0.628 0.372 0.000
S52.61 Fracture of lower end of both ulna and radius (open)
0.626 0.373 0.000
O23 Infections of genito-urinary tract in pregnancy
0.626 0.374 0.000
S80.8 Other superficial injuries of lower leg
0.626 0.374 0.000
S22.4 Multiple fractures of ribs
0.626 0.374 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.626 0.374 0.000
T20 Burn and corrosion of head and neck
0.625 0.375 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.625 0.375 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.625 0.375 0.000
B35-B49 Mycoses
0.625 0.375 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.625 0.375 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.625 0.375 0.000
H52.7 Disorder of refraction, unspecified
0.625 0.375 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.624 0.376 0.000
S52.10 Fracture of upper end of radius (closed)
0.624 0.376 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.624 0.376 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.624 0.376 0.000
G23 Other degenerative diseases of basal ganglia
0.623 0.377 0.000
G21 Secondary Parkinsonism
0.623 0.377 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.623 0.377 0.000
G22 Parkinsonism in diseases classified elsewhere
0.623 0.377 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.623 0.377 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.622 0.378 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.621 0.379 0.000
B65-B83 Helminthiases
0.621 0.379 0.000
B50-B64 Protozoal diseases
0.621 0.379 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.621 0.379 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.621 0.379 0.000
A75-A79 Rickettsioses
0.621 0.379 0.000
A70-A74 Other diseases caused by chlamydiae
0.621 0.379 0.000
A65-A69 Other spirochaetal diseases
0.621 0.379 0.000
A20-A28 Certain zoonotic bacterial diseases
0.621 0.379 0.000
A15-A19 Tuberculosis
0.621 0.379 0.000
S82.00 Fracture of patella (closed)
0.621 0.379 0.000
Q60-Q64 Congenital malformations of the urinary system
0.621 0.379 0.000
H49 Paralytic strabismus
0.621 0.379 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.620 0.379 0.000
O97 Death from sequelae of direct obstetric causes
0.620 0.379 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.620 0.379 0.000
O95 Obstetric death of unspecified cause
0.620 0.379 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.620 0.379 0.000
H90-H95 Other disorders of ear
0.620 0.380 0.000
S80.0 Contusion of knee
0.619 0.381 0.000
T93.2 Sequelae of other fractures of lower limb
0.619 0.381 0.000
O71.4 Obstetric high vaginal laceration alone
0.618 0.382 0.000
Y86 Sequelae of other accidents
0.618 0.382 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.618 0.382 0.000
N89 Other noninflammatory disorders of vagina
0.618 0.382 0.000
N05.9 Unspecified
0.616 0.384 0.000
S70 Superficial injury of hip and thigh
0.615 0.384 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.615 0.385 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.615 0.385 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.615 0.385 0.000
T42.3 Barbiturates
0.615 0.385 0.000
T42.2 Succinimides and oxazolidinediones
0.615 0.385 0.000
T42.1 Iminostilbenes
0.615 0.385 0.000
T42.0 Hydantoin derivatives
0.615 0.385 0.000
T43.9 Psychotropic drug, unspecified
0.614 0.385 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.614 0.385 0.000
T43.6 Psychostimulants with abuse potential
0.614 0.385 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.614 0.385 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.614 0.385 0.000
T50.4 Drugs affecting uric acid metabolism
0.614 0.386 0.000
S42 Fracture of shoulder and upper arm
0.613 0.387 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.612 0.387 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.612 0.387 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.612 0.388 0.000
S90.8 Other superficial injuries of ankle and foot
0.612 0.388 0.000
N87.0 Mild cervical dysplasia
0.611 0.389 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.611 0.389 0.000
F70-F79 Mental retardation
0.611 0.389 0.000
T93.1 Sequelae of fracture of femur
0.610 0.389 0.000
S71.1 Open wound of thigh
0.610 0.390 0.000
G95.8 Other specified diseases of spinal cord
0.610 0.390 0.000
O16 Unspecified maternal hypertension
0.610 0.390 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.609 0.391 0.000
G03 Meningitis due to other and unspecified causes
0.609 0.391 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.609 0.391 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.609 0.391 0.000
E20 Hypoparathyroidism
0.608 0.392 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.607 0.393 0.000
O03 Spontaneous abortion
0.607 0.393 0.000
N05.2 Diffuse membranous glomerulonephritis
0.607 0.393 0.000
S92.4 Fracture of great toe
0.606 0.394 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.606 0.394 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.606 0.394 0.000
H17 Corneal scars and opacities
0.606 0.394 0.000
H15 Disorders of sclera
0.606 0.394 0.000
O75.9 Complication of labour and delivery, unspecified
0.606 0.394 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.606 0.394 0.000
O75.4 Other complications of obstetric surgery and procedures
0.606 0.394 0.000
O75.3 Other infection during labour
0.606 0.394 0.000
O75.1 Shock during or following labour and delivery
0.606 0.394 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.606 0.394 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.606 0.394 0.000
Q35-Q37 Cleft lip and cleft palate
0.606 0.394 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.606 0.394 0.000
T93.0 Sequelae of open wound of lower limb
0.605 0.395 0.000
O47 False labour
0.605 0.395 0.000
E23 Hypofunction and other disorders of pituitary gland
0.605 0.395 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.604 0.396 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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