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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs55742391
log Bayes Factor = 8.79257
Chromosome 15   position 66,061,627  (GRCh37) Explore rs55742391 on Ensembl!
Variant rs55742391 is part of Cluster X0263

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
C15-C26 Malignant neoplasms of digestive organs
0.993 0.007 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.993 0.007 0.000
C64-C68 Malignant neoplasms of urinary tract
0.991 0.009 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.990 0.010 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.989 0.011 0.000
M45-M49 Spondylopathies
0.986 0.014 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.984 0.016 0.000
M50-M54 Other dorsopathies
0.983 0.017 0.000
C67 Malignant neoplasm of bladder
0.981 0.019 0.000
M54 Dorsalgia
0.975 0.025 0.000
C67.9 Bladder, unspecified
0.965 0.035 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.961 0.039 0.000
M48 Other spondylopathies
0.958 0.042 0.000
D50-D53 Nutritional anaemias
0.956 0.044 0.000
M54.5 Low back pain
0.956 0.044 0.000
B25-B34 Other viral diseases
0.954 0.046 0.000
A30-A49 Other bacterial diseases
0.948 0.052 0.000
Q60-Q64 Congenital malformations of the urinary system
0.946 0.054 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.945 0.055 0.000
M40-M43 Deforming dorsopathies
0.944 0.056 0.000
M48.0 Spinal stenosis
0.943 0.057 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.940 0.060 0.000
M47 Spondylosis
0.939 0.061 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.938 0.062 0.000
C15 Malignant neoplasm of oesophagus
0.936 0.064 0.000
M54.59 Low back pain (Site unspecified)
0.935 0.065 0.000
Chapter XX External causes of morbidity and mortality
0.934 0.066 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.932 0.068 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.929 0.071 0.000
C21 Malignant neoplasm of anus and anal canal
0.928 0.072 0.000
D41.4 Bladder
0.928 0.072 0.000
Q61 Cystic kidney disease
0.927 0.073 0.000
B34 Viral infection of unspecified site
0.926 0.074 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.923 0.077 0.000
M65-M68 Disorders of synovium and tendon
0.918 0.082 0.000
A49 Bacterial infection of unspecified site
0.917 0.083 0.000
Y43 Primarily systemic agents
0.917 0.083 0.000
D60-D64 Aplastic and other anaemias
0.916 0.084 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.915 0.085 0.000
M48.06 Spinal stenosis (Lumbar region)
0.913 0.087 0.000
L20-L30 Dermatitis and eczema
0.912 0.088 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.905 0.095 0.000
C44 Other malignant neoplasms of skin
0.905 0.095 0.000
Y43.3 Other antineoplastic drugs
0.904 0.096 0.000
B34.9 Viral infection, unspecified
0.904 0.096 0.000
D70 Agranulocytosis
0.903 0.097 0.000
M54.1 Radiculopathy
0.901 0.099 0.000
D51 Vitamin B12 deficiency anaemia
0.895 0.105 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.891 0.109 0.000
L81 Other disorders of pigmentation
0.888 0.112 0.000
M41 Scoliosis
0.885 0.115 0.000
M47.8 Other spondylosis
0.877 0.123 0.000
M80-M85 Disorders of bone density and structure
0.869 0.131 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.868 0.132 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.863 0.136 0.000
M05-M14 Inflammatory polyarthropathies
0.863 0.137 0.000
Q61.3 Polycystic kidney, unspecified
0.862 0.138 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.861 0.139 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.861 0.139 0.000
E65-E68 Obesity and other hyperalimentation
0.860 0.140 0.000
D61 Other aplastic anaemias
0.859 0.141 0.000
Chapter VI Diseases of the nervous system
0.859 0.141 0.000
M48.09 Spinal stenosis (Site unspecified)
0.856 0.144 0.000
E66 Obesity
0.855 0.145 0.000
L81.4 Other melanin hyperpigmentation
0.849 0.151 0.000
Q61.2 Polycystic kidney, adult type
0.848 0.152 0.000
L27 Dermatitis due to substances taken internally
0.845 0.155 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.845 0.155 0.000
M41.9 Scoliosis, unspecified
0.842 0.158 0.000
A49.0 Staphylococcal infection, unspecified
0.840 0.160 0.000
C15.9 Oesophagus, unspecified
0.840 0.160 0.000
E66.9 Obesity, unspecified
0.840 0.160 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.839 0.161 0.000
L85 Other epidermal thickening
0.837 0.163 0.000
D50 Iron deficiency anaemia
0.837 0.163 0.000
B95-B98 Bacterial, viral and other infectious agents
0.835 0.165 0.000
C67.2 Lateral wall of bladder
0.832 0.168 0.000
B02 Zoster [herpes zoster]
0.831 0.169 0.000
G90-G99 Other disorders of the nervous system
0.831 0.169 0.000
C44.0 Skin of lip
0.830 0.170 0.000
C83.3 Large cell (diffuse)
0.829 0.171 0.000
Chapter VIII Diseases of the ear and mastoid process
0.826 0.174 0.000
L50-L54 Urticaria and erythema
0.825 0.175 0.000
M54.56 Low back pain (Lumbar region)
0.823 0.177 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.821 0.179 0.000
D37.1 Stomach
0.818 0.182 0.000
D61.9 Aplastic anaemia, unspecified
0.818 0.182 0.000
D50.8 Other iron deficiency anaemias
0.816 0.184 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.815 0.185 0.000
M60-M63 Disorders of muscles
0.813 0.187 0.000
D46 Myelodysplastic syndromes
0.810 0.190 0.000
C67.6 Ureteric orifice
0.809 0.191 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.809 0.191 0.000
M47.9 Spondylosis, unspecified
0.809 0.191 0.000
C15.4 Middle third of oesophagus
0.808 0.192 0.000
C18 Malignant neoplasm of colon
0.807 0.193 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.805 0.195 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.805 0.195 0.000
D73 Diseases of spleen
0.805 0.195 0.000
M13 Other arthritis
0.802 0.198 0.000
C44.1 Skin of eyelid, including canthus
0.800 0.200 0.000
Y40 Systemic antibiotics
0.800 0.200 0.000
M47.82 Other spondylosis (Cervical region)
0.799 0.201 0.000
A49.8 Other bacterial infections of unspecified site
0.799 0.201 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.798 0.202 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.797 0.203 0.000
L89 Decubitus ulcer
0.796 0.204 0.000
M67 Other disorders of synovium and tendon
0.793 0.207 0.000
C21.1 Anal canal
0.793 0.207 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.793 0.207 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.792 0.208 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.791 0.209 0.000
Q80-Q89 Other congenital malformations
0.787 0.213 0.000
T66-T78 Other and unspecified effects of external causes
0.785 0.215 0.000
E66.8 Other obesity
0.783 0.217 0.000
X60-X84 Intentional self-harm
0.782 0.218 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.781 0.219 0.000
C44.5 Skin of trunk
0.781 0.219 0.000
S80-S89 Injuries to the knee and lower leg
0.780 0.220 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.779 0.221 0.000
C21.0 Anus, unspecified
0.778 0.222 0.000
M81 Osteoporosis without pathological fracture
0.777 0.223 0.000
L85.8 Other specified epidermal thickening
0.776 0.224 0.000
H65-H75 Diseases of middle ear and mastoid
0.775 0.225 0.000
M86-M90 Other osteopathies
0.773 0.227 0.000
D41.0 Kidney
0.773 0.227 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.772 0.228 0.000
L84 Corns and callosities
0.771 0.229 0.000
M54.4 Lumbago with sciatica
0.771 0.229 0.000
M65 Synovitis and tenosynovitis
0.770 0.230 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.770 0.230 0.000
G93 Other disorders of brain
0.769 0.231 0.000
A49.9 Bacterial infection, unspecified
0.768 0.232 0.000
M43 Other deforming dorsopathies
0.765 0.235 0.000
C44.4 Skin of scalp and neck
0.765 0.235 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.763 0.237 0.000
L29 Pruritus
0.756 0.244 0.000
A80-A89 Viral infections of the central nervous system
0.755 0.244 0.000
Y43.1 Antineoplastic antimetabolites
0.754 0.246 0.000
M54.12 Radiculopathy (Cervical region)
0.754 0.246 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.751 0.249 0.000
D00-D09 In situ neoplasms
0.750 0.250 0.000
C88 Malignant immunoproliferative diseases
0.750 0.250 0.000
D37.9 Digestive organ, unspecified
0.748 0.252 0.000
M51 Other intervertebral disk disorders
0.748 0.252 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.746 0.253 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.745 0.255 0.000
C66 Malignant neoplasm of ureter
0.744 0.256 0.000
D37.5 Rectum
0.744 0.256 0.000
Chapter VII Diseases of the eye and adnexa
0.744 0.256 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.743 0.257 0.000
M54.55 Low back pain (Thoracolumbar region)
0.743 0.257 0.000
Q61.0 Congenital single renal cyst
0.741 0.259 0.000
C67.5 Bladder neck
0.740 0.260 0.000
C16 Malignant neoplasm of stomach
0.739 0.261 0.000
Y43.4 Immunosuppressive agents
0.738 0.262 0.000
M54.19 Radiculopathy (Site unspecified)
0.737 0.263 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.734 0.266 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.734 0.266 0.000
Q21 Congenital malformations of cardiac septa
0.733 0.267 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.732 0.268 0.000
C23 Malignant neoplasm of gallbladder
0.731 0.269 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.731 0.269 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.731 0.269 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.730 0.269 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.730 0.270 0.000
C44.2 Skin of ear and external auricular canal
0.730 0.270 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.729 0.271 0.000
S10-S19 Injuries to the neck
0.728 0.272 0.000
M13.9 Arthritis, unspecified
0.726 0.274 0.000
M47.89 Other spondylosis (Site unspecified)
0.725 0.275 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.725 0.275 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.725 0.275 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.723 0.277 0.000
M48.02 Spinal stenosis (Cervical region)
0.722 0.278 0.000
A40 Streptococcal septicaemia
0.722 0.278 0.000
B99-B99 Other infectious diseases
0.721 0.279 0.000
M10 Gout
0.721 0.279 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.721 0.279 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.721 0.279 0.000
B65-B83 Helminthiases
0.720 0.280 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.718 0.282 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
D53 Other nutritional anaemias
0.716 0.284 0.000
B00 Herpesviral [herpes simplex] infections
0.715 0.285 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.713 0.287 0.000
M54.57 Low back pain (Lumbosacral region)
0.713 0.287 0.000
Q00-Q07 Congenital malformations of the nervous system
0.713 0.287 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
T23 Burn and corrosion of wrist and hand
0.712 0.288 0.000
C17 Malignant neoplasm of small intestine
0.712 0.288 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.712 0.288 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.712 0.288 0.000
L50 Urticaria
0.711 0.289 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.710 0.289 0.000
C65 Malignant neoplasm of renal pelvis
0.710 0.289 0.000
T18 Foreign body in alimentary tract
0.710 0.290 0.000
L10-L14 Bullous disorders
0.709 0.291 0.000
C51-C58 Malignant neoplasms of female genital organs
0.709 0.291 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.708 0.292 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.708 0.292 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.708 0.292 0.000
Y95 Nosocomial condition
0.708 0.292 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.707 0.293 0.000
C18.2 Ascending colon
0.707 0.293 0.000
M49 Spondylopathies in diseases classified elsewhere
0.707 0.293 0.000
C15.5 Lower third of oesophagus
0.707 0.293 0.000
M00-M03 Infectious arthropathies
0.707 0.293 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.706 0.294 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.705 0.295 0.000
Q35-Q37 Cleft lip and cleft palate
0.705 0.295 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.705 0.295 0.000
D37.2 Small intestine
0.704 0.296 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.704 0.296 0.000
S40-S49 Injuries to the shoulder and upper arm
0.704 0.296 0.000
M66 Spontaneous rupture of synovium and tendon
0.703 0.297 0.000
G93.8 Other specified disorders of brain
0.703 0.297 0.000
C67.8 Overlapping lesion of bladder
0.703 0.297 0.000
C67.7 Urachus
0.703 0.297 0.000
C67.0 Trigone of bladder
0.703 0.297 0.000
B02.2 Zoster with other nervous system involvement
0.703 0.297 0.000
M54.9 Dorsalgia, unspecified
0.702 0.298 0.000
L29.2 Pruritus vulvae
0.701 0.299 0.000
B34.8 Other viral infections of unspecified site
0.701 0.299 0.000
M54.8 Other dorsalgia
0.699 0.301 0.000
M54.0 Panniculitis affecting regions of neck and back
0.699 0.301 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.699 0.301 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.698 0.302 0.000
M67.8 Other specified disorders of synovium and tendon
0.697 0.303 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.697 0.303 0.000
H43-H45 Disorders of vitreous body and globe
0.697 0.303 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.697 0.303 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.697 0.303 0.000
A00-A09 Intestinal infectious diseases
0.697 0.303 0.000
W50-W64 Exposure to animate mechanical forces
0.696 0.304 0.000
C92 Myeloid leukaemia
0.695 0.305 0.000
M54.3 Sciatica
0.694 0.306 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.693 0.307 0.000
B35-B49 Mycoses
0.692 0.308 0.000
M53 Other dorsopathies, not elsewhere classified
0.692 0.308 0.000
L57.0 Actinic keratosis
0.692 0.308 0.000
C77.5 Intrapelvic lymph nodes
0.691 0.309 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.690 0.310 0.000
C67.3 Anterior wall of bladder
0.689 0.310 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.689 0.311 0.000
T78 Adverse effects, not elsewhere classified
0.689 0.311 0.000
D41.9 Urinary organ, unspecified
0.689 0.311 0.000
D41.7 Other urinary organs
0.689 0.311 0.000
D41.3 Urethra
0.689 0.311 0.000
D41.2 Ureter
0.689 0.311 0.000
D41.1 Renal pelvis
0.689 0.311 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.688 0.312 0.000
L83 Acanthosis nigricans
0.688 0.312 0.000
D40.1 Testis
0.688 0.312 0.000
M48.9 Spondylopathy, unspecified
0.687 0.313 0.000
M48.8 Other specified spondylopathies
0.687 0.313 0.000
M48.4 Fatigue fracture of vertebra
0.687 0.313 0.000
M48.3 Traumatic spondylopathy
0.687 0.313 0.000
M48.2 Kissing spine
0.687 0.313 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.687 0.313 0.000
D52 Folate deficiency anaemia
0.686 0.314 0.000
M54.54 Low back pain-Thoracic
0.685 0.315 0.000
M54.53 Low back pain-Cervicothoracic
0.685 0.315 0.000
M54.52 Low back pain-Cervical
0.685 0.315 0.000
M54.51 Low back pain-Occipit-atl-axl
0.685 0.315 0.000
D55-D59 Haemolytic anaemias
0.684 0.316 0.000
Y48 Anaesthetics and therapeutic gases
0.684 0.316 0.000
B33 Other viral diseases, not elsewhere classified
0.684 0.316 0.000
B30 Viral conjunctivitis
0.684 0.316 0.000
B27 Infectious mononucleosis
0.684 0.316 0.000
B26 Mumps
0.684 0.316 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.683 0.317 0.000
S86 Injury of muscle and tendon at lower leg level
0.683 0.317 0.000
B02.3 Zoster ocular disease
0.683 0.317 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.681 0.318 0.000
Chapter XXII Codes for special purposes
0.680 0.320 0.000
A48 Other bacterial diseases, not elsewhere classified
0.680 0.320 0.000
A44 Bartonellosis
0.680 0.320 0.000
A43 Nocardiosis
0.680 0.320 0.000
A42 Actinomycosis
0.680 0.320 0.000
A39 Meningococcal infection
0.680 0.320 0.000
A37 Whooping cough
0.680 0.320 0.000
A36 Diphtheria
0.680 0.320 0.000
A32 Listeriosis
0.680 0.320 0.000
A31 Infection due to other mycobacteria
0.680 0.320 0.000
A30 Leprosy [Hansen's disease]
0.680 0.320 0.000
A38 Scarlet fever
0.680 0.320 0.000
A35 Other tetanus
0.680 0.320 0.000
A34 Obstetrical tetanus
0.680 0.320 0.000
A33 Tetanus neonatorum
0.680 0.320 0.000
H30-H36 Disorders of choroid and retina
0.680 0.320 0.000
D62 Acute posthaemorrhagic anaemia
0.680 0.320 0.000
M62 Other disorders of muscle
0.679 0.321 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.679 0.321 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.678 0.322 0.000
M47.86 Other spondylosis (Lumbar region)
0.678 0.322 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.678 0.322 0.000
Q64 Other congenital malformations of urinary system
0.678 0.322 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.678 0.322 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.677 0.322 0.000
B02.9 Zoster without complication
0.678 0.322 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.677 0.322 0.000
L94 Other localised connective tissue disorders
0.677 0.322 0.000
L87 Transepidermal elimination disorders
0.677 0.322 0.000
L88 Pyoderma gangrenosum
0.677 0.322 0.000
L86 Keratoderma in diseases classified elsewhere
0.677 0.322 0.000
L80 Vitiligo
0.677 0.322 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.677 0.323 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.677 0.323 0.000
M42 Spinal osteochondrosis
0.677 0.323 0.000
M40 Kyphosis and lordosis
0.677 0.323 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.676 0.324 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.676 0.324 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.676 0.324 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.676 0.324 0.000
M48.04 Spinal stenosis (Thoracic region)
0.676 0.324 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.676 0.324 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.676 0.324 0.000
C77.2 Intra-abdominal lymph nodes
0.675 0.325 0.000
H60-H62 Diseases of external ear
0.674 0.326 0.000
L89.1 Stage II decubitus ulcer
0.674 0.326 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.674 0.326 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.674 0.326 0.000
D74 Methaemoglobinaemia
0.674 0.326 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.674 0.326 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.674 0.326 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.673 0.326 0.000
T20 Burn and corrosion of head and neck
0.673 0.327 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.672 0.327 0.000
C95 Leukaemia of unspecified cell type
0.672 0.327 0.000
C94 Other leukaemias of specified cell type
0.672 0.327 0.000
C93 Monocytic leukaemia
0.672 0.327 0.000
C86 Other specified types of T/NK-cell lymphoma
0.672 0.327 0.000
M15-M19 Arthrosis
0.672 0.328 0.000
C15.8 Overlapping lesion of oesophagus
0.671 0.328 0.000
C15.3 Upper third of oesophagus
0.671 0.328 0.000
C15.2 Abdominal part of oesophagus
0.671 0.328 0.000
C15.1 Thoracic part of oesophagus
0.671 0.328 0.000
C15.0 Cervical part of oesophagus
0.671 0.328 0.000
Y35-Y36 Legal intervention and operations of war
0.669 0.330 0.000
Y10-Y34 Event of undetermined intent
0.669 0.330 0.000
Y00-Y09 Assault
0.669 0.330 0.000
X85-X99 Assault
0.669 0.330 0.000
X50-X57 Overexertion, travel and privation
0.669 0.330 0.000
X30-X39 Exposure to forces of nature
0.669 0.330 0.000
X10-X19 Contact with heat and hot substances
0.669 0.330 0.000
X00-X09 Exposure to smoke, fire and flames
0.669 0.330 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.669 0.330 0.000
W75-W84 Other accidental threats to breathing
0.669 0.330 0.000
W65-W74 Accidental drowning and submersion
0.669 0.330 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.330 0.000
V95-V97 Air and space transport accidents
0.669 0.330 0.000
V90-V94 Water transport accidents
0.669 0.330 0.000
V70-V79 Bus occupant injured in transport accident
0.669 0.330 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.669 0.330 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.669 0.330 0.000
V40-V49 Car occupant injured in transport accident
0.669 0.330 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.669 0.330 0.000
V01-V09 Pedestrian injured in transport accident
0.669 0.330 0.000
M13.0 Polyarthritis, unspecified
0.669 0.331 0.000
M47.2 Other spondylosis with radiculopathy
0.669 0.331 0.000
D09 Carcinoma in situ of other and unspecified sites
0.668 0.332 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.667 0.333 0.000
M84 Disorders of continuity of bone
0.667 0.333 0.000
T33-T35 Frostbite
0.666 0.334 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.666 0.334 0.000
D37.0 Lip, oral cavity and pharynx
0.666 0.334 0.000
C21.2 Cloacogenic zone
0.665 0.334 0.000
L20 Atopic dermatitis
0.664 0.335 0.000
Q61.9 Cystic kidney disease, unspecified
0.664 0.335 0.000
Q61.8 Other cystic kidney diseases
0.664 0.335 0.000
Q61.5 Medullary cystic kidney
0.664 0.335 0.000
Q61.4 Renal dysplasia
0.664 0.335 0.000
Q61.1 Polycystic kidney, infantile type
0.664 0.335 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.664 0.336 0.000
B34.4 Papovirus infection, unspecified
0.664 0.336 0.000
B34.3 Parvovirus infection, unspecified
0.664 0.336 0.000
B34.2 Coronavirus infection, unspecified
0.664 0.336 0.000
B34.1 Enterovirus infection, unspecified
0.664 0.336 0.000
B34.0 Adenovirus infection, unspecified
0.664 0.336 0.000
Y57 Other and unspecified drugs and medicaments
0.664 0.336 0.000
S50-S59 Injuries to the elbow and forearm
0.664 0.336 0.000
D38.0 Larynx
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.663 0.337 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.663 0.337 0.000
D73.1 Hypersplenism
0.663 0.337 0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.662 0.338 0.000
Y43.0 Antiallergic and antiemetic drugs
0.662 0.338 0.000
Y59 Other and unspecified vaccines and biological substances
0.662 0.338 0.000
Y58 Bacterial vaccines
0.662 0.338 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.662 0.338 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.662 0.338 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.662 0.338 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.662 0.338 0.000
C25 Malignant neoplasm of pancreas
0.662 0.338 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.661 0.338 0.000
G90 Disorders of autonomic nervous system
0.661 0.339 0.000
S60-S69 Injuries to the wrist and hand
0.661 0.339 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.660 0.340 0.000
L82 Seborrhoeic keratosis
0.659 0.341 0.000
M54.2 Cervicalgia
0.659 0.341 0.000
M13.98 Arthritis, unspecified (Other)
0.659 0.341 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.659 0.341 0.000
C26.0 Intestinal tract, part unspecified
0.659 0.341 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.658 0.342 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.658 0.342 0.000
A49.3 Mycoplasma infection, unspecified
0.658 0.342 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.658 0.342 0.000
T17 Foreign body in respiratory tract
0.658 0.342 0.000
Y43.9 Primarily systemic agent, unspecified
0.657 0.343 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.657 0.343 0.000
Y43.6 Enzymes, not elsewhere classified
0.657 0.343 0.000
Y43.5 Acidifying and alkalising agents
0.657 0.343 0.000
Y43.2 Antineoplastic natural products
0.657 0.343 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.657 0.343 0.000
G95 Other diseases of spinal cord
0.657 0.343 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.657 0.343 0.000
D03 Melanoma in situ
0.656 0.344 0.000
D37.3 Appendix
0.656 0.344 0.000
E20-E35 Disorders of other endocrine glands
0.656 0.344 0.000
M47.1 Other spondylosis with myelopathy
0.656 0.344 0.000
D47.2 Monoclonal gammopathy
0.656 0.344 0.000
S90-S99 Injuries to the ankle and foot
0.655 0.345 0.000
H71 Cholesteatoma of middle ear
0.654 0.346 0.000
L25 Unspecified contact dermatitis
0.654 0.346 0.000
L24 Irritant contact dermatitis
0.654 0.346 0.000
L23 Allergic contact dermatitis
0.654 0.346 0.000
L21 Seborrhoeic dermatitis
0.654 0.346 0.000
L26 Exfoliative dermatitis
0.654 0.346 0.000
L22 Diaper [napkin] dermatitis
0.654 0.346 0.000
G70-G73 Diseases of myoneural junction and muscle
0.654 0.346 0.000
Q21.1 Atrial septal defect
0.654 0.346 0.000
D73.8 Other diseases of spleen
0.654 0.346 0.000
M81.9 Osteoporosis, unspecified
0.653 0.347 0.000
C67.1 Dome of bladder
0.653 0.347 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.651 0.349 0.000
B25 Cytomegaloviral disease
0.649 0.350 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.649 0.351 0.000
B06 Rubella [German measles]
0.649 0.351 0.000
B05 Measles
0.649 0.351 0.000
B01 Varicella [chickenpox]
0.649 0.351 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.649 0.351 0.000
B04 Monkeypox
0.649 0.351 0.000
B03 Smallpox
0.649 0.351 0.000
W20-W49 Exposure to inanimate mechanical forces
0.649 0.351 0.000
C44.8 Overlapping lesion of skin
0.649 0.351 0.000
L05 Pilonidal cyst
0.648 0.352 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.648 0.352 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.647 0.353 0.000
H65 Nonsuppurative otitis media
0.647 0.353 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.646 0.354 0.000
M54.14 Radiculopathy (Thoracic region)
0.646 0.354 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.646 0.354 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.646 0.354 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.646 0.354 0.000
M43.1 Spondylolisthesis
0.646 0.354 0.000
H72 Perforation of tympanic membrane
0.645 0.355 0.000
E50-E64 Other nutritional deficiencies
0.644 0.356 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.642 0.358 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.642 0.358 0.000
D51.2 Transcobalamin II deficiency
0.642 0.358 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.642 0.358 0.000
A46 Erysipelas
0.641 0.359 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.641 0.359 0.000
T79-T79 Certain early complications of trauma
0.640 0.360 0.000
M80 Osteoporosis with pathological fracture
0.640 0.360 0.000
X20-X29 Contact with venomous animals and plants
0.639 0.361 0.000
Q39 Congenital malformations of oesophagus
0.639 0.361 0.000
C83.7 Burkitt's tumour
0.638 0.361 0.000
C83.6 Undifferentiated (diffuse)
0.638 0.361 0.000
C83.5 Lymphoblastic (diffuse)
0.638 0.361 0.000
C83.4 Immunoblastic (diffuse)
0.638 0.361 0.000
C83.2 Mixed small and large cell (diffuse)
0.638 0.361 0.000
C83.1 Small cleaved cell (diffuse)
0.638 0.361 0.000
A41 Other septicaemia
0.638 0.362 0.000
Y40.0 Penicillins
0.638 0.362 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.638 0.362 0.000
C83.0 Small cell (diffuse)
0.637 0.363 0.000
M11 Other crystal arthropathies
0.637 0.363 0.000
M54.6 Pain in thoracic spine
0.637 0.363 0.000
L81.8 Other specified disorders of pigmentation
0.637 0.363 0.000
L81.7 Pigmented purpuric dermatosis
0.637 0.363 0.000
L81.6 Other disorders of diminished melanin formation
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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