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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs56190744
log Bayes Factor = 18.1608
Chromosome 15   position 78,170,282  (GRCh37) Explore rs56190744 on Ensembl!
Variant rs56190744 is part of Cluster X0153

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
D10-D36 Benign neoplasms
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
Chapter XI Diseases of the digestive system
0.987 0.013 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.987 0.013 0.000
D17 Benign lipomatous neoplasm
0.984 0.016 0.000
Chapter V Mental and behavioural disorders
0.984 0.016 0.000
J90-J94 Other diseases of pleura
0.982 0.018 0.000
R07 Pain in throat and chest
0.979 0.021 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.976 0.024 0.000
J43 Emphysema
0.970 0.030 0.000
J44 Other chronic obstructive pulmonary disease
0.968 0.032 0.000
F30-F39 Mood [affective] disorders
0.968 0.032 0.000
N60-N64 Disorders of breast
0.964 0.036 0.000
D24 Benign neoplasm of breast
0.956 0.044 0.000
J43.9 Emphysema, unspecified
0.949 0.051 0.000
Chapter XX External causes of morbidity and mortality
0.948 0.052 0.000
R07.4 Chest pain, unspecified
0.945 0.055 0.000
Chapter VI Diseases of the nervous system
0.945 0.055 0.000
J30-J39 Other diseases of upper respiratory tract
0.944 0.056 0.000
F32 Depressive episode
0.944 0.056 0.000
J90 Pleural effusion, not elsewhere classified
0.944 0.056 0.000
I51 Complications and ill-defined descriptions of heart disease
0.940 0.060 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.937 0.063 0.000
Chapter I Certain infectious and parasitic diseases
0.933 0.067 0.000
N10-N16 Renal tubulo-interstitial diseases
0.930 0.070 0.000
I35 Nonrheumatic aortic valve disorders
0.929 0.071 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.922 0.078 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.920 0.080 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.919 0.081 0.000
R07.3 Other chest pain
0.918 0.082 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.915 0.085 0.000
I50 Heart failure
0.915 0.085 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.909 0.091 0.000
C64-C68 Malignant neoplasms of urinary tract
0.906 0.094 0.000
J45 Asthma
0.901 0.099 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.899 0.101 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.899 0.101 0.000
K35-K38 Diseases of appendix
0.895 0.105 0.000
N63 Unspecified lump in breast
0.895 0.105 0.000
J38.3 Other diseases of vocal cords
0.886 0.114 0.000
I46 Cardiac arrest
0.886 0.114 0.000
R00 Abnormalities of heart beat
0.884 0.116 0.000
K90-K93 Other diseases of the digestive system
0.883 0.117 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.883 0.117 0.000
I51.7 Cardiomegaly
0.881 0.119 0.000
F32.9 Depressive episode, unspecified
0.880 0.120 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.875 0.125 0.000
I35.0 Aortic (valve) stenosis
0.873 0.127 0.000
N20-N23 Urolithiasis
0.870 0.130 0.000
N13 Obstructive and reflux uropathy
0.870 0.130 0.000
D22 Melanocytic naevi
0.869 0.131 0.000
N99-N99 Other disorders of the genitourinary system
0.869 0.131 0.000
K81 Cholecystitis
0.863 0.137 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.861 0.139 0.000
I34 Nonrheumatic mitral valve disorders
0.857 0.143 0.000
B25-B34 Other viral diseases
0.853 0.147 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.850 0.150 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.849 0.151 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.849 0.151 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.849 0.151 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.849 0.151 0.000
J20-J22 Other acute lower respiratory infections
0.848 0.152 0.000
S00-S09 Injuries to the head
0.845 0.155 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.844 0.156 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.840 0.160 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.837 0.163 0.000
R50-R69 General symptoms and signs
0.837 0.163 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.828 0.172 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.828 0.172 0.000
D23 Other benign neoplasms of skin
0.821 0.179 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.819 0.181 0.000
A00-A09 Intestinal infectious diseases
0.818 0.182 0.000
G90-G99 Other disorders of the nervous system
0.818 0.182 0.000
K92 Other diseases of digestive system
0.817 0.183 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.816 0.184 0.000
S60-S69 Injuries to the wrist and hand
0.816 0.184 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.815 0.185 0.000
R00.0 Tachycardia, unspecified
0.814 0.186 0.000
D32 Benign neoplasm of meninges
0.814 0.186 0.000
I05-I09 Chronic rheumatic heart diseases
0.814 0.186 0.000
I60-I69 Cerebrovascular diseases
0.813 0.187 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.811 0.189 0.000
J92 Pleural plaque
0.811 0.189 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.811 0.189 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.810 0.190 0.000
J45.9 Asthma, unspecified
0.809 0.191 0.000
I51.9 Heart disease, unspecified
0.809 0.191 0.000
I38 Endocarditis, valve unspecified
0.809 0.191 0.000
C15-C26 Malignant neoplasms of digestive organs
0.808 0.192 0.000
R42 Dizziness and giddiness
0.807 0.193 0.000
N23 Unspecified renal colic
0.806 0.194 0.000
J40 Bronchitis, not specified as acute or chronic
0.805 0.194 0.000
S20-S29 Injuries to the thorax
0.805 0.195 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.804 0.196 0.000
K81.1 Chronic cholecystitis
0.804 0.196 0.000
F33 Recurrent depressive disorder
0.803 0.196 0.000
D50-D53 Nutritional anaemias
0.802 0.198 0.000
C50-C50 Malignant neoplasm of breast
0.802 0.198 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.801 0.199 0.000
J93 Pneumothorax
0.799 0.201 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.796 0.204 0.000
K37 Unspecified appendicitis
0.796 0.204 0.000
B34 Viral infection of unspecified site
0.795 0.205 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.795 0.205 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.793 0.207 0.000
K82 Other diseases of gallbladder
0.792 0.208 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.789 0.211 0.000
R51 Headache
0.787 0.213 0.000
T79-T79 Certain early complications of trauma
0.787 0.213 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.787 0.213 0.000
D12.2 Ascending colon
0.785 0.215 0.000
N60 Benign mammary dysplasia
0.785 0.215 0.000
I46.0 Cardiac arrest with successful resuscitation
0.785 0.215 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.785 0.215 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.785 0.215 0.000
S40-S49 Injuries to the shoulder and upper arm
0.784 0.216 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.784 0.216 0.000
I50.1 Left ventricular failure
0.784 0.216 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.783 0.217 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.783 0.217 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.782 0.218 0.000
I50.0 Congestive heart failure
0.782 0.218 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.779 0.221 0.000
D26 Other benign neoplasms of uterus
0.778 0.222 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.777 0.223 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.777 0.223 0.000
N00-N08 Glomerular diseases
0.775 0.225 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.774 0.226 0.000
F32.0 Mild depressive episode
0.774 0.226 0.000
G40-G47 Episodic and paroxysmal disorders
0.773 0.227 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.772 0.228 0.000
G81 Hemiplegia
0.772 0.228 0.000
D25 Leiomyoma of uterus
0.771 0.229 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.770 0.230 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.770 0.230 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.770 0.230 0.000
J60-J70 Lung diseases due to external agents
0.770 0.230 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.767 0.233 0.000
J35 Chronic diseases of tonsils and adenoids
0.766 0.234 0.000
C67 Malignant neoplasm of bladder
0.766 0.234 0.000
K83 Other diseases of biliary tract
0.764 0.236 0.000
Y84.8 Other medical procedures
0.761 0.239 0.000
N64 Other disorders of breast
0.761 0.239 0.000
N13.8 Other obstructive and reflux uropathy
0.760 0.240 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.760 0.240 0.000
R07.2 Precordial pain
0.760 0.240 0.000
I34.0 Mitral (valve) insufficiency
0.759 0.241 0.000
J91 Pleural effusion in conditions classified elsewhere
0.757 0.243 0.000
J46 Status asthmaticus
0.757 0.243 0.000
R53 Malaise and fatigue
0.757 0.243 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.757 0.243 0.000
A30-A49 Other bacterial diseases
0.756 0.244 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.756 0.244 0.000
N61 Inflammatory disorders of breast
0.755 0.245 0.000
B34.9 Viral infection, unspecified
0.754 0.246 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.754 0.246 0.000
E10-E14 Diabetes mellitus
0.754 0.246 0.000
I27 Other pulmonary heart diseases
0.754 0.246 0.000
N30-N39 Other diseases of urinary system
0.753 0.247 0.000
T81 Complications of procedures, not elsewhere classified
0.752 0.248 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.751 0.248 0.000
N13.3 Other and unspecified hydronephrosis
0.751 0.249 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.750 0.250 0.000
I73 Other peripheral vascular diseases
0.749 0.251 0.000
I33 Acute and subacute endocarditis
0.748 0.252 0.000
K40-K46 Hernia
0.748 0.252 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.746 0.254 0.000
T43.2 Other and unspecified antidepressants
0.745 0.255 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.745 0.255 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.744 0.256 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.743 0.257 0.000
X60-X84 Intentional self-harm
0.742 0.258 0.000
F31 Bipolar affective disorder
0.739 0.260 0.000
J22 Unspecified acute lower respiratory infection
0.739 0.261 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.737 0.263 0.000
C51-C58 Malignant neoplasms of female genital organs
0.737 0.263 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.737 0.263 0.000
I42 Cardiomyopathy
0.736 0.264 0.000
I77 Other disorders of arteries and arterioles
0.735 0.265 0.000
R45 Symptoms and signs involving emotional state
0.735 0.265 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.734 0.266 0.000
I35.8 Other aortic valve disorders
0.733 0.267 0.000
N25-N29 Other disorders of kidney and ureter
0.733 0.267 0.000
D22.5 Melanocytic naevi of trunk
0.732 0.268 0.000
R47-R49 Symptoms and signs involving speech and voice
0.731 0.269 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.729 0.270 0.000
N17-N19 Renal failure
0.729 0.270 0.000
I69 Sequelae of cerebrovascular disease
0.728 0.272 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.728 0.272 0.000
R02 Gangrene, not elsewhere classified
0.727 0.273 0.000
D23.7 Skin of lower limb, including hip
0.727 0.273 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.727 0.273 0.000
K35 Acute appendicitis
0.725 0.275 0.000
J30 Vasomotor and allergic rhinitis
0.725 0.275 0.000
S80-S89 Injuries to the knee and lower leg
0.724 0.275 0.000
N62 Hypertrophy of breast
0.724 0.276 0.000
I49 Other cardiac arrhythmias
0.724 0.276 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.724 0.276 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.723 0.277 0.000
D12.0 Caecum
0.723 0.277 0.000
T40.2 Other opioids
0.722 0.278 0.000
D12.3 Transverse colon
0.722 0.278 0.000
K12 Stomatitis and related lesions
0.722 0.278 0.000
R52 Pain, not elsewhere classified
0.722 0.278 0.000
S70-S79 Injuries to the hip and thigh
0.721 0.279 0.000
N10 Acute tubulo-interstitial nephritis
0.721 0.279 0.000
I47 Paroxysmal tachycardia
0.719 0.281 0.000
I45 Other conduction disorders
0.719 0.281 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.719 0.281 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
R04 Haemorrhage from respiratory passages
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
D31 Benign neoplasm of eye and adnexa
0.716 0.284 0.000
D30 Benign neoplasm of urinary organs
0.716 0.284 0.000
D29 Benign neoplasm of male genital organs
0.716 0.284 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.716 0.284 0.000
D19 Benign neoplasm of mesothelial tissue
0.716 0.284 0.000
D16 Benign neoplasm of bone and articular cartilage
0.716 0.284 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.716 0.284 0.000
D10 Benign neoplasm of mouth and pharynx
0.716 0.284 0.000
G81.9 Hemiplegia, unspecified
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
R30-R39 Symptoms and signs involving the urinary system
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.284 0.000
I48 Atrial fibrillation and flutter
0.715 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.284 0.000
I40 Acute myocarditis
0.715 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.284 0.000
I37 Pulmonary valve disorders
0.715 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.284 0.000
I30 Acute pericarditis
0.715 0.284 0.000
D50 Iron deficiency anaemia
0.715 0.284 0.000
J38.4 Oedema of larynx
0.715 0.285 0.000
A04 Other bacterial intestinal infections
0.715 0.285 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.285 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.711 0.289 0.000
D60-D64 Aplastic and other anaemias
0.710 0.290 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.709 0.290 0.000
K07 Dentofacial anomalies [including malocclusion]
0.709 0.291 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.709 0.291 0.000
D34 Benign neoplasm of thyroid gland
0.709 0.291 0.000
S00 Superficial injury of head
0.708 0.292 0.000
K82.4 Cholesterolosis of gallbladder
0.708 0.292 0.000
E70-E90 Metabolic disorders
0.707 0.293 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.707 0.293 0.000
R07.0 Pain in throat
0.706 0.294 0.000
N30 Cystitis
0.706 0.294 0.000
G30-G32 Other degenerative diseases of the nervous system
0.706 0.294 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.706 0.294 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.706 0.294 0.000
J45.0 Predominantly allergic asthma
0.706 0.294 0.000
F99-F99 Unspecified mental disorder
0.705 0.294 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.705 0.294 0.000
F80-F89 Disorders of psychological development
0.705 0.294 0.000
F70-F79 Mental retardation
0.705 0.294 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.294 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.705 0.294 0.000
J94 Other pleural conditions
0.704 0.296 0.000
S90-S99 Injuries to the ankle and foot
0.704 0.296 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.702 0.298 0.000
Chapter XXII Codes for special purposes
0.702 0.298 0.000
R07.1 Chest pain on breathing
0.702 0.298 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.701 0.299 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.700 0.300 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.700 0.300 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.700 0.300 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.700 0.300 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.700 0.300 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.700 0.300 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.700 0.300 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.700 0.300 0.000
T36 Poisoning by systemic antibiotics
0.700 0.300 0.000
Y84.6 Urinary catheterisation
0.699 0.301 0.000
J31.0 Chronic rhinitis
0.698 0.302 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.698 0.302 0.000
K86 Other diseases of pancreas
0.698 0.302 0.000
R33 Retention of urine
0.698 0.302 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.698 0.302 0.000
J09-J18 Influenza and pneumonia
0.697 0.303 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.697 0.303 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.697 0.303 0.000
J42 Unspecified chronic bronchitis
0.697 0.303 0.000
F32.1 Moderate depressive episode
0.695 0.305 0.000
J43.8 Other emphysema
0.695 0.305 0.000
J43.2 Centrilobular emphysema
0.695 0.305 0.000
J43.1 Panlobular emphysema
0.695 0.305 0.000
J43.0 MacLeod's syndrome
0.695 0.305 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.695 0.305 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.695 0.305 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.694 0.305 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.694 0.306 0.000
F38 Other mood [affective] disorders
0.694 0.306 0.000
F34 Persistent mood [affective] disorders
0.694 0.306 0.000
F30 Manic episode
0.694 0.306 0.000
F39 Unspecified mood [affective] disorder
0.694 0.306 0.000
K55-K64 Other diseases of intestines
0.691 0.309 0.000
F20 Schizophrenia
0.690 0.310 0.000
W20-W49 Exposure to inanimate mechanical forces
0.690 0.310 0.000
C45 Mesothelioma
0.689 0.311 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.688 0.312 0.000
I46.9 Cardiac arrest, unspecified
0.687 0.313 0.000
D23.3 Skin of other and unspecified parts of face
0.687 0.313 0.000
I50.9 Heart failure, unspecified
0.686 0.314 0.000
R40 Somnolence, stupor and coma
0.685 0.314 0.000
T51 Toxic effect of alcohol
0.685 0.314 0.000
K08 Other disorders of teeth and supporting structures
0.684 0.316 0.000
I71 Aortic aneurysm and dissection
0.684 0.316 0.000
S50-S59 Injuries to the elbow and forearm
0.684 0.316 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.684 0.316 0.000
K70-K77 Diseases of liver
0.683 0.316 0.000
D00-D09 In situ neoplasms
0.683 0.317 0.000
T86 Failure and rejection of transplanted organs and tissues
0.683 0.317 0.000
C34 Malignant neoplasm of bronchus and lung
0.683 0.317 0.000
T66-T78 Other and unspecified effects of external causes
0.683 0.317 0.000
E50-E64 Other nutritional deficiencies
0.683 0.317 0.000
B35-B49 Mycoses
0.683 0.317 0.000
G93 Other disorders of brain
0.681 0.319 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.680 0.320 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.679 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.679 0.320 0.000
Y10-Y34 Event of undetermined intent
0.679 0.320 0.000
Y00-Y09 Assault
0.679 0.320 0.000
X85-X99 Assault
0.679 0.320 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.679 0.320 0.000
X50-X57 Overexertion, travel and privation
0.679 0.320 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.679 0.320 0.000
X30-X39 Exposure to forces of nature
0.679 0.320 0.000
X20-X29 Contact with venomous animals and plants
0.679 0.320 0.000
X10-X19 Contact with heat and hot substances
0.679 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.679 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.679 0.320 0.000
W75-W84 Other accidental threats to breathing
0.679 0.320 0.000
W65-W74 Accidental drowning and submersion
0.679 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.679 0.320 0.000
V98-V99 Other and unspecified transport accidents
0.679 0.320 0.000
V95-V97 Air and space transport accidents
0.679 0.320 0.000
V90-V94 Water transport accidents
0.679 0.320 0.000
V80-V89 Other land transport accidents
0.679 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.679 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.679 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.679 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.679 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.679 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.679 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.679 0.320 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.678 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.678 0.322 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.678 0.322 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.678 0.322 0.000
K14 Diseases of tongue
0.678 0.322 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.677 0.322 0.000
J37 Chronic laryngitis and laryngotracheitis
0.677 0.323 0.000
J32 Chronic sinusitis
0.677 0.323 0.000
F32.8 Other depressive episodes
0.677 0.323 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.677 0.323 0.000
S60 Superficial injury of wrist and hand
0.675 0.325 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.674 0.326 0.000
I51.6 Cardiovascular disease, unspecified
0.674 0.326 0.000
I51.5 Myocardial degeneration
0.674 0.326 0.000
I51.4 Myocarditis, unspecified
0.674 0.326 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.674 0.326 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.674 0.326 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.674 0.326 0.000
I51.0 Cardiac septal defect, acquired
0.674 0.326 0.000
D46 Myelodysplastic syndromes
0.674 0.326 0.000
C71 Malignant neoplasm of brain
0.674 0.326 0.000
V10-V19 Pedal cyclist injured in transport accident
0.673 0.326 0.000
A49 Bacterial infection of unspecified site
0.673 0.327 0.000
E20-E35 Disorders of other endocrine glands
0.672 0.328 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.672 0.328 0.000
K85 Acute pancreatitis
0.672 0.328 0.000
K05 Gingivitis and periodontal diseases
0.672 0.328 0.000
S06 Intracranial injury
0.671 0.329 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.671 0.329 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.670 0.329 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.670 0.330 0.000
C18 Malignant neoplasm of colon
0.670 0.330 0.000
K65-K67 Diseases of peritoneum
0.669 0.331 0.000
B99-B99 Other infectious diseases
0.669 0.331 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.669 0.331 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.669 0.331 0.000
B65-B83 Helminthiases
0.669 0.331 0.000
B50-B64 Protozoal diseases
0.669 0.331 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.669 0.331 0.000
B15-B19 Viral hepatitis
0.669 0.331 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.669 0.331 0.000
A75-A79 Rickettsioses
0.669 0.331 0.000
A70-A74 Other diseases caused by chlamydiae
0.669 0.331 0.000
A65-A69 Other spirochaetal diseases
0.669 0.331 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.669 0.331 0.000
A20-A28 Certain zoonotic bacterial diseases
0.669 0.331 0.000
A15-A19 Tuberculosis
0.669 0.331 0.000
J00-J06 Acute upper respiratory infections
0.668 0.332 0.000
J93.9 Pneumothorax, unspecified
0.668 0.332 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.667 0.333 0.000
N15 Other renal tubulo-interstitial diseases
0.667 0.333 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.667 0.333 0.000
N11 Chronic tubulo-interstitial nephritis
0.667 0.333 0.000
Y95 Nosocomial condition
0.667 0.333 0.000
I35.9 Aortic valve disorder, unspecified
0.666 0.334 0.000
J92.0 Pleural plaque with presence of asbestos
0.666 0.334 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.666 0.334 0.000
A04.8 Other specified bacterial intestinal infections
0.665 0.335 0.000
I27.2 Other secondary pulmonary hypertension
0.665 0.335 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.664 0.336 0.000
J39 Other diseases of upper respiratory tract
0.664 0.336 0.000
I73.0 Raynaud's syndrome
0.664 0.336 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.663 0.337 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.662 0.338 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.661 0.338 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.660 0.340 0.000
R46 Symptoms and signs involving appearance and behaviour
0.660 0.340 0.000
R43 Disturbances of smell and taste
0.660 0.340 0.000
C50 Malignant neoplasm of breast
0.660 0.340 0.000
T43.9 Psychotropic drug, unspecified
0.659 0.341 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.659 0.341 0.000
T43.6 Psychostimulants with abuse potential
0.659 0.341 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.659 0.341 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.659 0.341 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.659 0.341 0.000
R00.1 Bradycardia, unspecified
0.657 0.343 0.000
D55-D59 Haemolytic anaemias
0.656 0.344 0.000
K42 Umbilical hernia
0.656 0.344 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.653 0.347 0.000
J38.6 Stenosis of larynx
0.651 0.348 0.000
J38.5 Laryngeal spasm
0.651 0.348 0.000
J38.2 Nodules of vocal cords
0.651 0.348 0.000
J38.1 Polyp of vocal cord and larynx
0.651 0.348 0.000
J38.0 Paralysis of vocal cords and larynx
0.651 0.348 0.000
C60-C63 Malignant neoplasms of male genital organs
0.651 0.349 0.000
I63 Cerebral infarction
0.650 0.350 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.650 0.350 0.000
C66 Malignant neoplasm of ureter
0.650 0.350 0.000
C65 Malignant neoplasm of renal pelvis
0.650 0.350 0.000
K59 Other functional intestinal disorders
0.649 0.351 0.000
K83.1 Obstruction of bile duct
0.649 0.351 0.000
G43 Migraine
0.649 0.351 0.000
D11 Benign neoplasm of major salivary glands
0.648 0.352 0.000
D25.2 Subserosal leiomyoma of uterus
0.648 0.352 0.000
G20-G26 Extrapyramidal and movement disorders
0.647 0.353 0.000
J45.8 Mixed asthma
0.646 0.354 0.000
J45.1 Nonallergic asthma
0.646 0.354 0.000
S02 Fracture of skull and facial bones
0.645 0.355 0.000
N60.4 Mammary duct ectasia
0.645 0.355 0.000
T87 Complications peculiar to reattachment and amputation
0.645 0.355 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.645 0.355 0.000
S62 Fracture at wrist and hand level
0.645 0.355 0.000
C01 Malignant neoplasm of base of tongue
0.645 0.355 0.000
D80-D89 Certain disorders involving the immune mechanism
0.644 0.356 0.000
D32.9 Meninges, unspecified
0.644 0.356 0.000
G91 Hydrocephalus
0.643 0.356 0.000
K92.0 Haematemesis
0.643 0.357 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.643 0.357 0.000
N30.9 Cystitis, unspecified
0.643 0.357 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.642 0.358 0.000
K38 Other diseases of appendix
0.642 0.358 0.000
K36 Other appendicitis
0.642 0.358 0.000
I07 Rheumatic tricuspid valve diseases
0.641 0.359 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.641 0.359 0.000
R01 Cardiac murmurs and other cardiac sounds
0.640 0.360 0.000
D25.1 Intramural leiomyoma of uterus
0.640 0.360 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.640 0.360 0.000
R52.1 Chronic intractable pain
0.639 0.361 0.000
F22 Persistent delusional disorders
0.639 0.361 0.000
T39.1 4-Aminophenol derivatives
0.639 0.361 0.000
N99.2 Postprocedural adhesions of vagina
0.638 0.362 0.000
K92.1 Melaena
0.637 0.363 0.000
G82 Paraplegia and tetraplegia
0.637 0.363 0.000
D36 Benign neoplasm of other and unspecified sites
0.636 0.364 0.000
I08 Multiple valve diseases
0.636 0.364 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.636 0.364 0.000
D32.0 Cerebral meninges
0.635 0.365 0.000
I46.1 Sudden cardiac death, so described
0.635 0.365 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.635 0.365 0.000
E10 Insulin-dependent diabetes mellitus
0.635 0.365 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.635 0.365 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.635 0.365 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.633 0.366 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.633 0.367 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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