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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs56286522
log Bayes Factor = 14.5169
Chromosome 1   position 99,517,636  (GRCh37) Explore rs56286522 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.998 0.002 0.000
D60-D64 Aplastic and other anaemias
0.991 0.009 0.000
C79 Secondary malignant neoplasm of other sites
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
M20-M25 Other joint disorders
0.984 0.016 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
D64 Other anaemias
0.980 0.020 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.978 0.022 0.000
C15-C26 Malignant neoplasms of digestive organs
0.974 0.026 0.000
R60 Oedema, not elsewhere classified
0.973 0.027 0.000
D64.9 Anaemia, unspecified
0.972 0.028 0.000
R50 Fever of unknown origin
0.968 0.032 0.000
M05-M14 Inflammatory polyarthropathies
0.964 0.036 0.000
Chapter VI Diseases of the nervous system
0.961 0.039 0.000
R60.0 Localised oedema
0.957 0.043 0.000
Chapter XI Diseases of the digestive system
0.957 0.043 0.000
M80-M85 Disorders of bone density and structure
0.955 0.045 0.000
R50.9 Fever, unspecified
0.950 0.050 0.000
M20 Acquired deformities of fingers and toes
0.948 0.052 0.000
K70-K77 Diseases of liver
0.945 0.055 0.000
C60-C63 Malignant neoplasms of male genital organs
0.942 0.058 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.940 0.060 0.000
E20-E35 Disorders of other endocrine glands
0.938 0.062 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.935 0.065 0.000
R52 Pain, not elsewhere classified
0.931 0.069 0.000
D50-D53 Nutritional anaemias
0.929 0.071 0.000
W00-W19 Falls
0.928 0.072 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.926 0.074 0.000
R59 Enlarged lymph nodes
0.913 0.087 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.909 0.091 0.000
D80-D89 Certain disorders involving the immune mechanism
0.907 0.093 0.000
M81 Osteoporosis without pathological fracture
0.898 0.102 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.892 0.108 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.892 0.108 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.887 0.113 0.000
C78.7 Secondary malignant neoplasm of liver
0.887 0.113 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.884 0.116 0.000
C25 Malignant neoplasm of pancreas
0.883 0.117 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.877 0.123 0.000
W19 Unspecified fall
0.876 0.124 0.000
D51 Vitamin B12 deficiency anaemia
0.874 0.126 0.000
M06 Other rheumatoid arthritis
0.872 0.128 0.000
S80-S89 Injuries to the knee and lower leg
0.871 0.129 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.871 0.129 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.870 0.129 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.870 0.130 0.000
K70 Alcoholic liver disease
0.868 0.132 0.000
R59.1 Generalised enlarged lymph nodes
0.867 0.133 0.000
Chapter XXI Factors influencing health status and contact with health services
0.867 0.133 0.000
K76 Other diseases of liver
0.866 0.134 0.000
C20 Malignant neoplasm of rectum
0.864 0.136 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.863 0.136 0.000
S00-S09 Injuries to the head
0.863 0.137 0.000
K55-K64 Other diseases of intestines
0.861 0.139 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.861 0.139 0.000
M81.9 Osteoporosis, unspecified
0.857 0.143 0.000
E70-E90 Metabolic disorders
0.856 0.144 0.000
C61 Malignant neoplasm of prostate
0.854 0.146 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.853 0.147 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.853 0.147 0.000
S70-S79 Injuries to the hip and thigh
0.852 0.148 0.000
K62 Other diseases of anus and rectum
0.848 0.152 0.000
M20.2 Hallux rigidus
0.847 0.153 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.840 0.160 0.000
S32 Fracture of lumbar spine and pelvis
0.839 0.161 0.000
S40-S49 Injuries to the shoulder and upper arm
0.838 0.162 0.000
Chapter XXII Codes for special purposes
0.837 0.163 0.000
R52.1 Chronic intractable pain
0.837 0.163 0.000
C78.0 Secondary malignant neoplasm of lung
0.836 0.164 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.835 0.165 0.000
G56 Mononeuropathies of upper limb
0.834 0.166 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.834 0.166 0.000
E83 Disorders of mineral metabolism
0.833 0.167 0.000
Y43 Primarily systemic agents
0.833 0.167 0.000
K62.1 Rectal polyp
0.833 0.167 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.826 0.174 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.826 0.174 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.824 0.176 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.823 0.177 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.822 0.178 0.000
D61 Other aplastic anaemias
0.821 0.179 0.000
M65-M68 Disorders of synovium and tendon
0.821 0.179 0.000
M25 Other joint disorders, not elsewhere classified
0.820 0.180 0.000
C62 Malignant neoplasm of testis
0.818 0.182 0.000
W19.9 Unspecified place
0.817 0.183 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.812 0.188 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.811 0.189 0.000
K82 Other diseases of gallbladder
0.809 0.191 0.000
R56 Convulsions, not elsewhere classified
0.809 0.191 0.000
Z60 Problems related to social environment
0.808 0.192 0.000
D70 Agranulocytosis
0.808 0.192 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.807 0.192 0.000
E65-E68 Obesity and other hyperalimentation
0.803 0.197 0.000
M35 Other systemic involvement of connective tissue
0.802 0.198 0.000
M20.3 Other deformity of hallux (acquired)
0.802 0.198 0.000
S82 Fracture of lower leg, including ankle
0.801 0.199 0.000
R63 Symptoms and signs concerning food and fluid intake
0.800 0.200 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.798 0.202 0.000
C15 Malignant neoplasm of oesophagus
0.798 0.202 0.000
K08 Other disorders of teeth and supporting structures
0.798 0.202 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.797 0.203 0.000
M20.1 Hallux valgus (acquired)
0.797 0.203 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.795 0.205 0.000
C90.0 Multiple myeloma
0.794 0.206 0.000
K62.5 Haemorrhage of anus and rectum
0.794 0.206 0.000
E23 Hypofunction and other disorders of pituitary gland
0.793 0.207 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.793 0.207 0.000
M22 Disorders of patella
0.792 0.208 0.000
S90-S99 Injuries to the ankle and foot
0.792 0.208 0.000
Z60.2 Living alone
0.791 0.209 0.000
R54 Senility
0.787 0.213 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.786 0.214 0.000
R41.0 Disorientation, unspecified
0.786 0.214 0.000
G20-G26 Extrapyramidal and movement disorders
0.786 0.214 0.000
M06.9 Rheumatoid arthritis, unspecified
0.783 0.217 0.000
R21 Rash and other nonspecific skin eruption
0.780 0.220 0.000
G56.0 Carpal tunnel syndrome
0.780 0.220 0.000
S32.0 Fracture of lumbar vertebra
0.777 0.223 0.000
K72 Hepatic failure, not elsewhere classified
0.777 0.223 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.776 0.224 0.000
M11 Other crystal arthropathies
0.776 0.224 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.776 0.224 0.000
G30-G32 Other degenerative diseases of the nervous system
0.776 0.224 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.775 0.225 0.000
R47-R49 Symptoms and signs involving speech and voice
0.775 0.225 0.000
R52.2 Other chronic pain
0.775 0.225 0.000
K76.9 Liver disease, unspecified
0.775 0.225 0.000
S00 Superficial injury of head
0.774 0.226 0.000
M31 Other necrotising vasculopathies
0.772 0.228 0.000
C78.2 Secondary malignant neoplasm of pleura
0.771 0.229 0.000
E10-E14 Diabetes mellitus
0.769 0.231 0.000
C25.9 Pancreas, unspecified
0.768 0.232 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.767 0.233 0.000
E83.5 Disorders of calcium metabolism
0.767 0.233 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.766 0.234 0.000
K74 Fibrosis and cirrhosis of liver
0.764 0.236 0.000
T66-T78 Other and unspecified effects of external causes
0.764 0.236 0.000
M21 Other acquired deformities of limbs
0.764 0.236 0.000
M10 Gout
0.763 0.237 0.000
E50-E64 Other nutritional deficiencies
0.761 0.239 0.000
D62 Acute posthaemorrhagic anaemia
0.760 0.240 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.759 0.241 0.000
M80 Osteoporosis with pathological fracture
0.758 0.241 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.757 0.243 0.000
Y52 Agents primarily affecting the cardiovascular system
0.757 0.243 0.000
Y43.3 Other antineoplastic drugs
0.756 0.244 0.000
S20-S29 Injuries to the thorax
0.753 0.247 0.000
M85 Other disorders of bone density and structure
0.753 0.247 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.751 0.249 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.750 0.250 0.000
M07 Psoriatic and enteropathic arthropathies
0.750 0.250 0.000
K82.8 Other specified diseases of gallbladder
0.750 0.250 0.000
X60-X84 Intentional self-harm
0.748 0.252 0.000
R53 Malaise and fatigue
0.748 0.252 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.746 0.254 0.000
W19.2 School, other institution and public administrative area
0.746 0.254 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.744 0.256 0.000
M05 Seropositive rheumatoid arthritis
0.743 0.257 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.743 0.257 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.742 0.258 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.742 0.258 0.000
K08.3 Retained dental root
0.741 0.259 0.000
C25.0 Head of pancreas
0.740 0.260 0.000
M86-M90 Other osteopathies
0.740 0.260 0.000
E22 Hyperfunction of pituitary gland
0.738 0.262 0.000
M13 Other arthritis
0.737 0.263 0.000
D86 Sarcoidosis
0.737 0.263 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.737 0.263 0.000
E21.0 Primary hyperparathyroidism
0.737 0.263 0.000
M81.98 Osteoporosis, unspecified (Other)
0.737 0.263 0.000
L50-L54 Urticaria and erythema
0.736 0.263 0.000
C64-C68 Malignant neoplasms of urinary tract
0.736 0.264 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.736 0.264 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.735 0.265 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.734 0.266 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.734 0.266 0.000
S82.8 Fractures of other parts of lower leg
0.733 0.267 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.733 0.267 0.000
K70.9 Alcoholic liver disease, unspecified
0.733 0.267 0.000
K70.3 Alcoholic cirrhosis of liver
0.731 0.269 0.000
E27 Other disorders of adrenal gland
0.730 0.270 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.729 0.271 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.729 0.271 0.000
W06 Fall involving bed
0.729 0.271 0.000
C62.9 Testis, unspecified
0.729 0.271 0.000
M20.0 Deformity of finger(s)
0.728 0.271 0.000
L90 Atrophic disorders of skin
0.727 0.272 0.000
R55 Syncope and collapse
0.726 0.274 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.725 0.275 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.723 0.277 0.000
C80 Malignant neoplasm without specification of site
0.722 0.278 0.000
G56.2 Lesion of ulnar nerve
0.722 0.278 0.000
Y40 Systemic antibiotics
0.722 0.278 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.720 0.280 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
R52.0 Acute pain
0.719 0.281 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
E83.1 Disorders of iron metabolism
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.717 0.283 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.717 0.283 0.000
D55-D59 Haemolytic anaemias
0.717 0.283 0.000
D52 Folate deficiency anaemia
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
E83.4 Disorders of magnesium metabolism
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.285 0.000
R62 Lack of expected normal physiological development
0.715 0.285 0.000
R57 Shock, not elsewhere classified
0.715 0.285 0.000
R64 Cachexia
0.715 0.285 0.000
R58 Haemorrhage, not elsewhere classified
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
G90-G99 Other disorders of the nervous system
0.715 0.285 0.000
M24 Other specific joint derangements
0.714 0.286 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.714 0.286 0.000
M25.5 Pain in joint
0.713 0.287 0.000
C16 Malignant neoplasm of stomach
0.712 0.288 0.000
S71 Open wound of hip and thigh
0.711 0.289 0.000
K59 Other functional intestinal disorders
0.711 0.289 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.711 0.289 0.000
K86 Other diseases of pancreas
0.710 0.290 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.709 0.291 0.000
C79.6 Secondary malignant neoplasm of ovary
0.709 0.291 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.709 0.291 0.000
C79.2 Secondary malignant neoplasm of skin
0.709 0.291 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.709 0.291 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.708 0.292 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.708 0.292 0.000
E40-E46 Malnutrition
0.708 0.292 0.000
L84 Corns and callosities
0.708 0.292 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.705 0.295 0.000
M34 Systemic sclerosis
0.705 0.295 0.000
M33 Dermatopolymyositis
0.705 0.295 0.000
M32 Systemic lupus erythematosus
0.705 0.295 0.000
M30 Polyarteritis nodosa and related conditions
0.705 0.295 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.704 0.296 0.000
Chapter I Certain infectious and parasitic diseases
0.704 0.296 0.000
C81 Hodgkin's disease
0.703 0.297 0.000
D64.8 Other specified anaemias
0.702 0.298 0.000
D64.4 Congenital dyserythropoietic anaemia
0.702 0.298 0.000
D64.3 Other sideroblastic anaemias
0.702 0.298 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.702 0.298 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.702 0.298 0.000
D64.0 Hereditary sideroblastic anaemia
0.702 0.298 0.000
K75 Other inflammatory liver diseases
0.702 0.298 0.000
K55 Vascular disorders of intestine
0.701 0.299 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.701 0.299 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.701 0.299 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.701 0.299 0.000
S82.3 Fracture of lower end of tibia
0.701 0.299 0.000
D00-D09 In situ neoplasms
0.701 0.299 0.000
D61.9 Aplastic anaemia, unspecified
0.700 0.300 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.700 0.300 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.699 0.301 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.699 0.301 0.000
C21 Malignant neoplasm of anus and anal canal
0.699 0.301 0.000
C17 Malignant neoplasm of small intestine
0.699 0.301 0.000
C23 Malignant neoplasm of gallbladder
0.699 0.301 0.000
M67 Other disorders of synovium and tendon
0.699 0.301 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.698 0.301 0.000
R60.1 Generalised oedema
0.698 0.302 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.696 0.303 0.000
K76.6 Portal hypertension
0.695 0.305 0.000
M20.5 Other deformities of toe(s) (acquired)
0.695 0.305 0.000
G70-G73 Diseases of myoneural junction and muscle
0.695 0.305 0.000
R50.8 Other specified fever
0.694 0.306 0.000
R50.2 Drug-induced fever
0.694 0.306 0.000
R50.1 Persistent fever
0.694 0.306 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.692 0.308 0.000
C18 Malignant neoplasm of colon
0.692 0.308 0.000
M06.0 Seronegative rheumatoid arthritis
0.692 0.308 0.000
K35-K38 Diseases of appendix
0.692 0.308 0.000
M14 Arthropathies in other diseases classified elsewhere
0.691 0.309 0.000
M12 Other specific arthropathies
0.691 0.309 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.691 0.309 0.000
M08 Juvenile arthritis
0.691 0.309 0.000
C92 Myeloid leukaemia
0.690 0.310 0.000
E23.0 Hypopituitarism
0.689 0.310 0.000
L20-L30 Dermatitis and eczema
0.689 0.311 0.000
S00.8 Superficial injury of other parts of head
0.688 0.312 0.000
K04 Diseases of pulp and periapical tissues
0.687 0.312 0.000
W20-W49 Exposure to inanimate mechanical forces
0.687 0.313 0.000
K70.4 Alcoholic hepatic failure
0.687 0.313 0.000
S41 Open wound of shoulder and upper arm
0.687 0.313 0.000
M70-M79 Other soft tissue disorders
0.687 0.313 0.000
M84 Disorders of continuity of bone
0.685 0.315 0.000
M83 Adult osteomalacia
0.685 0.315 0.000
M82 Osteoporosis in diseases classified elsewhere
0.685 0.315 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.685 0.315 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.684 0.316 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.684 0.316 0.000
R61 Hyperhidrosis
0.683 0.316 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.683 0.316 0.000
R23 Other skin changes
0.682 0.318 0.000
E28 Ovarian dysfunction
0.681 0.319 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.679 0.321 0.000
R68 Other general symptoms and signs
0.679 0.321 0.000
R60.9 Oedema, unspecified
0.678 0.321 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.677 0.322 0.000
K77 Liver disorders in diseases classified elsewhere
0.677 0.323 0.000
K73 Chronic hepatitis, not elsewhere classified
0.677 0.323 0.000
K71 Toxic liver disease
0.677 0.323 0.000
Chapter IX Diseases of the circulatory system
0.677 0.323 0.000
Y45.0 Opioids and related analgesics
0.676 0.323 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.676 0.324 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.676 0.324 0.000
C60 Malignant neoplasm of penis
0.676 0.324 0.000
C71 Malignant neoplasm of brain
0.676 0.324 0.000
Y59 Other and unspecified vaccines and biological substances
0.674 0.326 0.000
Y58 Bacterial vaccines
0.674 0.326 0.000
Y57 Other and unspecified drugs and medicaments
0.674 0.326 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.674 0.326 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.674 0.326 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.674 0.326 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.674 0.326 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.674 0.326 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.674 0.326 0.000
Y48 Anaesthetics and therapeutic gases
0.674 0.326 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.674 0.326 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.674 0.326 0.000
Y44 Agents primarily affecting blood constituents
0.674 0.326 0.000
R56.8 Other and unspecified convulsions
0.674 0.326 0.000
C91 Lymphoid leukaemia
0.673 0.327 0.000
S72 Fracture of femur
0.673 0.327 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.673 0.327 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.673 0.327 0.000
E34 Other endocrine disorders
0.673 0.327 0.000
E32 Diseases of thymus
0.673 0.327 0.000
E31 Polyglandular dysfunction
0.673 0.327 0.000
E30 Disorders of puberty, not elsewhere classified
0.673 0.327 0.000
E29 Testicular dysfunction
0.673 0.327 0.000
E26 Hyperaldosteronism
0.673 0.327 0.000
E25 Adrenogenital disorders
0.673 0.327 0.000
E24 Cushing's syndrome
0.673 0.327 0.000
E20 Hypoparathyroidism
0.673 0.327 0.000
D73 Diseases of spleen
0.673 0.327 0.000
M40-M43 Deforming dorsopathies
0.672 0.328 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.671 0.328 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.671 0.329 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.670 0.330 0.000
C95 Leukaemia of unspecified cell type
0.670 0.330 0.000
C94 Other leukaemias of specified cell type
0.670 0.330 0.000
C93 Monocytic leukaemia
0.670 0.330 0.000
C88 Malignant immunoproliferative diseases
0.670 0.330 0.000
C86 Other specified types of T/NK-cell lymphoma
0.670 0.330 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.670 0.330 0.000
Chapter VII Diseases of the eye and adnexa
0.670 0.330 0.000
E66 Obesity
0.670 0.330 0.000
S89 Other and unspecified injuries of lower leg
0.669 0.331 0.000
R63.0 Anorexia
0.669 0.331 0.000
K07 Dentofacial anomalies [including malocclusion]
0.669 0.331 0.000
L08 Other local infections of skin and subcutaneous tissue
0.669 0.331 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.668 0.332 0.000
K62.8 Other specified diseases of anus and rectum
0.668 0.332 0.000
K82.4 Cholesterolosis of gallbladder
0.667 0.333 0.000
D53 Other nutritional anaemias
0.666 0.334 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.666 0.334 0.000
W18 Other fall on same level
0.665 0.334 0.000
W17 Other fall from one level to another
0.665 0.334 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.665 0.334 0.000
W15 Fall from cliff
0.665 0.334 0.000
W14 Fall from tree
0.665 0.334 0.000
W13 Fall from, out of or through building or structure
0.665 0.334 0.000
W12 Fall on and from scaffolding
0.665 0.334 0.000
W11 Fall on and from ladder
0.665 0.334 0.000
W10 Fall on and from stairs and steps
0.665 0.334 0.000
W09 Fall involving playground equipment
0.665 0.334 0.000
W08 Fall involving other furniture
0.665 0.334 0.000
W07 Fall involving chair
0.665 0.334 0.000
W05 Fall involving wheelchair
0.665 0.334 0.000
W04 Fall while being carried or supported by other persons
0.665 0.334 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.665 0.334 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.665 0.334 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.665 0.334 0.000
W00 Fall on same level involving ice and snow
0.665 0.334 0.000
S01 Open wound of head
0.665 0.335 0.000
L10-L14 Bullous disorders
0.664 0.336 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.662 0.338 0.000
D46 Myelodysplastic syndromes
0.661 0.339 0.000
L85 Other epidermal thickening
0.659 0.341 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.659 0.341 0.000
M20.4 Other hammer toe(s) (acquired)
0.658 0.342 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.658 0.342 0.000
V10-V19 Pedal cyclist injured in transport accident
0.658 0.342 0.000
K72.9 Hepatic failure, unspecified
0.657 0.343 0.000
C15.9 Oesophagus, unspecified
0.656 0.344 0.000
S06 Intracranial injury
0.656 0.344 0.000
R59.9 Enlarged lymph nodes, unspecified
0.654 0.345 0.000
M35.0 Sicca syndrome [Sjogren]
0.654 0.346 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.652 0.348 0.000
S37 Injury of urinary and pelvic organs
0.652 0.348 0.000
S36 Injury of intra-abdominal organs
0.652 0.348 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.652 0.348 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.652 0.348 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.652 0.348 0.000
S31 Open wound of abdomen, lower back and pelvis
0.652 0.348 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.652 0.348 0.000
K12 Stomatitis and related lesions
0.652 0.348 0.000
K62.4 Stenosis of anus and rectum
0.651 0.348 0.000
D84 Other immunodeficiencies
0.650 0.349 0.000
D83 Common variable immunodeficiency
0.650 0.349 0.000
D82 Immunodeficiency associated with other major defects
0.650 0.349 0.000
D81 Combined immunodeficiencies
0.650 0.349 0.000
D80 Immunodeficiency with predominantly antibody defects
0.650 0.349 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.650 0.350 0.000
C51-C58 Malignant neoplasms of female genital organs
0.650 0.350 0.000
Z63 Other problems related to primary support group, including family circumstances
0.649 0.351 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.648 0.352 0.000
M22.2 Patellofemoral disorders
0.648 0.352 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.648 0.352 0.000
T39.0 Salicylates
0.646 0.354 0.000
K02 Dental caries
0.646 0.354 0.000
M50-M54 Other dorsopathies
0.646 0.354 0.000
R52.9 Pain, unspecified
0.646 0.354 0.000
E14 Unspecified diabetes mellitus
0.644 0.356 0.000
G25 Other extrapyramidal and movement disorders
0.644 0.356 0.000
M81.8 Other osteoporosis
0.644 0.356 0.000
M81.6 Localised osteoporosis [Lequesne]
0.644 0.356 0.000
M81.5 Idiopathic osteoporosis
0.644 0.356 0.000
M81.4 Drug-induced osteoporosis
0.644 0.356 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.644 0.356 0.000
M81.2 Osteoporosis of disuse
0.644 0.356 0.000
M81.1 Postoophorectomy osteoporosis
0.644 0.356 0.000
M81.0 Postmenopausal osteoporosis
0.644 0.356 0.000
S81 Open wound of lower leg
0.643 0.357 0.000
L89 Decubitus ulcer
0.643 0.357 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.643 0.357 0.000
R81 Glycosuria
0.642 0.358 0.000
S42 Fracture of shoulder and upper arm
0.641 0.358 0.000
E00-E07 Disorders of thyroid gland
0.641 0.358 0.000
E10 Insulin-dependent diabetes mellitus
0.641 0.359 0.000
S90 Superficial injury of ankle and foot
0.641 0.359 0.000
M11.2 Other chondrocalcinosis
0.641 0.359 0.000
R50.0 Fever with chills
0.640 0.360 0.000
R46 Symptoms and signs involving appearance and behaviour
0.639 0.360 0.000
R43 Disturbances of smell and taste
0.639 0.360 0.000
S40 Superficial injury of shoulder and upper arm
0.639 0.361 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.639 0.361 0.000
D72 Other disorders of white blood cells
0.637 0.362 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.637 0.363 0.000
S32.5 Fracture of pubis
0.637 0.363 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.636 0.364 0.000
D74 Methaemoglobinaemia
0.636 0.364 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.636 0.364 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.636 0.364 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.636 0.364 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.635 0.365 0.000
Chapter VIII Diseases of the ear and mastoid process
0.635 0.365 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.635 0.365 0.000
Z36 Antenatal screening
0.635 0.365 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.635 0.365 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.634 0.365 0.000
G40-G47 Episodic and paroxysmal disorders
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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