TreeWAS – Variant ID: rs56369933

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter II Neoplasms	1.000	0.000
D10-D36 Benign neoplasms	1.000	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001
I10 Essential (primary) hypertension	0.999	0.001
I10-I15 Hypertensive diseases	0.999	0.001
Z86.4 Personal history of psychoactive substance abuse	0.998	0.002
Z86 Personal history of certain other diseases	0.998	0.002
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.998	0.002
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.998	0.002
Chapter XXI Factors influencing health status and contact with health services	0.998	0.002
M20-M25 Other joint disorders	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.995	0.005
M80-M85 Disorders of bone density and structure	0.987	0.013
Chapter VIII Diseases of the ear and mastoid process	0.986	0.014
M23 Internal derangement of knee	0.984	0.016
Chapter XX External causes of morbidity and mortality	0.973	0.027
D12.2 Ascending colon	0.967	0.033
Chapter XII Diseases of the skin and subcutaneous tissue	0.965	0.035
D12.5 Sigmoid colon	0.960	0.040
M81 Osteoporosis without pathological fracture	0.960	0.040
Chapter VI Diseases of the nervous system	0.959	0.041
I60-I69 Cerebrovascular diseases	0.952	0.048
H65-H75 Diseases of middle ear and mastoid	0.945	0.055
G40-G47 Episodic and paroxysmal disorders	0.939	0.061
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.938	0.062
M81.9 Osteoporosis, unspecified	0.933	0.067
Chapter XIV Diseases of the genitourinary system	0.929	0.071
Chapter X Diseases of the respiratory system	0.925	0.075
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.922	0.078
H80-H83 Diseases of inner ear	0.921	0.079
I64 Stroke, not specified as haemorrhage or infarction	0.917	0.083
M65-M68 Disorders of synovium and tendon	0.915	0.085
D12.0 Caecum	0.913	0.087
I70-I79 Diseases of arteries, arterioles and capillaries	0.913	0.087
M23.2 Derangement of meniscus due to old tear or injury	0.909	0.091
L80-L99 Other disorders of the skin and subcutaneous tissue	0.907	0.093
S60-S69 Injuries to the wrist and hand	0.905	0.095
J40-J47 Chronic lower respiratory diseases	0.905	0.095
M81.99 Osteoporosis, unspecified (Site unspecified)	0.904	0.096
D24 Benign neoplasm of breast	0.904	0.096
M23.8 Other internal derangements of knee	0.898	0.102
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.898	0.102
M05-M14 Inflammatory polyarthropathies	0.896	0.104
T66-T78 Other and unspecified effects of external causes	0.889	0.111
Z87 Personal history of other diseases and conditions	0.884	0.116
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.882	0.118
D12.3 Transverse colon	0.881	0.119
D37-D48 Neoplasms of uncertain or unknown behaviour	0.878	0.122
J20-J22 Other acute lower respiratory infections	0.877	0.123
D23 Other benign neoplasms of skin	0.874	0.126
Q20-Q28 Congenital malformations of the circulatory system	0.871	0.129
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.870	0.130
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.869	0.131
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.863	0.137
M15-M19 Arthrosis	0.862	0.138
N20-N23 Urolithiasis	0.861	0.139
D32 Benign neoplasm of meninges	0.857	0.143
W00-W19 Falls	0.857	0.143
L00-L08 Infections of the skin and subcutaneous tissue	0.857	0.143
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.855	0.145
M06 Other rheumatoid arthritis	0.853	0.147
S62 Fracture at wrist and hand level	0.849	0.151
Z97 Presence of other devices	0.847	0.153
H83 Other diseases of inner ear	0.846	0.154
J22 Unspecified acute lower respiratory infection	0.843	0.157
L02 Cutaneous abscess, furuncle and carbuncle	0.837	0.163
G00-G09 Inflammatory diseases of the central nervous system	0.837	0.163
M23.3 Other meniscus derangements	0.835	0.165
H65 Nonsuppurative otitis media	0.831	0.169
T92 Sequelae of injuries of upper limb	0.830	0.169
M19 Other arthrosis	0.830	0.170
S50-S59 Injuries to the elbow and forearm	0.829	0.171
M06.9 Rheumatoid arthritis, unspecified	0.829	0.171
Z00-Z13 Persons encountering health services for examination and investigation	0.827	0.173
M22 Disorders of patella	0.826	0.174
J45 Asthma	0.826	0.174
I74 Arterial embolism and thrombosis	0.825	0.175
Z90 Acquired absence of organs, not elsewhere classified	0.825	0.175
Z89 Acquired absence of limb	0.823	0.177
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.822	0.178
J47 Bronchiectasis	0.822	0.178
G44 Other headache syndromes	0.822	0.178
M67 Other disorders of synovium and tendon	0.821	0.179
G90-G99 Other disorders of the nervous system	0.820	0.180
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.820	0.180
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.819	0.181
L60-L75 Disorders of skin appendages	0.818	0.182
D36 Benign neoplasm of other and unspecified sites	0.818	0.182
Z86.7 Personal history of diseases of the circulatory system	0.817	0.183
L90 Atrophic disorders of skin	0.816	0.184
G47 Sleep disorders	0.814	0.186
V10-V19 Pedal cyclist injured in transport accident	0.809	0.190
G43 Migraine	0.809	0.190
D12.9 Anus and anal canal	0.809	0.191
N40-N51 Diseases of male genital organs	0.808	0.192
M20 Acquired deformities of fingers and toes	0.807	0.193
Q23 Congenital malformations of aortic and mitral valves	0.807	0.193
M35 Other systemic involvement of connective tissue	0.806	0.194
H60-H62 Diseases of external ear	0.805	0.195
M80 Osteoporosis with pathological fracture	0.804	0.196
Z03 Medical observation and evaluation for suspected diseases and conditions	0.803	0.197
M86-M90 Other osteopathies	0.802	0.198
C15-C26 Malignant neoplasms of digestive organs	0.802	0.198
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.801	0.199
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.801	0.199
Z03.8 Observation for other suspected diseases and conditions	0.801	0.199
C60-C63 Malignant neoplasms of male genital organs	0.800	0.200
M24 Other specific joint derangements	0.798	0.201
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.797	0.203
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.797	0.203
D29 Benign neoplasm of male genital organs	0.795	0.205
T15-T19 Effects of foreign body entering through natural orifice	0.794	0.206
D13.2 Duodenum	0.794	0.206
S10-S19 Injuries to the neck	0.793	0.207
H83.0 Labyrinthitis	0.792	0.208
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.792	0.208
I05-I09 Chronic rheumatic heart diseases	0.792	0.208
M19.9 Arthrosis, unspecified	0.791	0.209
M85 Other disorders of bone density and structure	0.791	0.209
I69 Sequelae of cerebrovascular disease	0.791	0.209
S62.6 Fracture of other finger	0.787	0.213
I73 Other peripheral vascular diseases	0.785	0.215
H71 Cholesteatoma of middle ear	0.783	0.217
D16 Benign neoplasm of bone and articular cartilage	0.782	0.218
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.782	0.218
Chapter XXII Codes for special purposes	0.782	0.218
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.779	0.221
M84 Disorders of continuity of bone	0.776	0.224
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.776	0.224
Z80 Family history of malignant neoplasm	0.776	0.224
M91-M94 Chondropathies	0.775	0.224
C83 Diffuse non-Hodgkin's lymphoma	0.774	0.226
M21 Other acquired deformities of limbs	0.774	0.226
N00-N08 Glomerular diseases	0.773	0.227
N60-N64 Disorders of breast	0.772	0.228
J42 Unspecified chronic bronchitis	0.772	0.228
Z87.4 Personal history of diseases of the genito-urinary system	0.772	0.228
M81.4 Drug-induced osteoporosis	0.770	0.230
M19.91 Arthrosis, unspecified (Shoulder region)	0.766	0.234
N20 Calculus of kidney and ureter	0.764	0.236
T93 Sequelae of injuries of lower limb	0.764	0.236
N23 Unspecified renal colic	0.763	0.237
G40 Epilepsy	0.762	0.238
Chapter IV Endocrine, nutritional and metabolic diseases	0.761	0.239
Q23.1 Congenital insufficiency of aortic valve	0.761	0.239
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.760	0.240
W20-W49 Exposure to inanimate mechanical forces	0.760	0.240
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.760	0.240
M23.4 Loose body in knee	0.759	0.240
L10-L14 Bullous disorders	0.759	0.241
Z87.0 Personal history of diseases of the respiratory system	0.758	0.242
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.758	0.242
Z88.0 Personal history of allergy to penicillin	0.758	0.242
Z11 Special screening examination for infectious and parasitic diseases	0.757	0.243
Z98 Other postsurgical states	0.756	0.244
D32.0 Cerebral meninges	0.756	0.244
M67.8 Other specified disorders of synovium and tendon	0.754	0.246
L84 Corns and callosities	0.753	0.247
S70-S79 Injuries to the hip and thigh	0.752	0.248
L97 Ulcer of lower limb, not elsewhere classified	0.752	0.248
H70 Mastoiditis and related conditions	0.752	0.248
I11 Hypertensive heart disease	0.752	0.248
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.752	0.248
T68 Hypothermia	0.751	0.249
M81.98 Osteoporosis, unspecified (Other)	0.751	0.249
Z86.6 Personal history of diseases of the nervous system and sense organs	0.751	0.249
D12.6 Colon, unspecified	0.751	0.249
T92.2 Sequelae of fracture at wrist and hand level	0.748	0.252
C45 Mesothelioma	0.748	0.252
N40 Hyperplasia of prostate	0.747	0.253
Z85 Personal history of malignant neoplasm	0.747	0.253
I62 Other nontraumatic intracranial haemorrhage	0.746	0.254
M65 Synovitis and tenosynovitis	0.746	0.254
H81 Disorders of vestibular function	0.746	0.254
D14 Benign neoplasm of middle ear and respiratory system	0.745	0.255
L92 Granulomatous disorders of skin and subcutaneous tissue	0.744	0.256
Z88.1 Personal history of allergy to other antibiotic agents	0.743	0.257
D21 Other benign neoplasms of connective and other soft tissue	0.743	0.257
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.743	0.257
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.742	0.258
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.742	0.258
D22 Melanocytic naevi	0.741	0.259
I61 Intracerebral haemorrhage	0.741	0.259
M35.0 Sicca syndrome [Sjogren]	0.741	0.259
Z86.5 Personal history of other mental and behavioural disorders	0.740	0.260
N10-N16 Renal tubulo-interstitial diseases	0.740	0.260
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.740	0.260
M20.4 Other hammer toe(s) (acquired)	0.739	0.261
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.738	0.262
D12.4 Descending colon	0.738	0.262
J45.9 Asthma, unspecified	0.737	0.263
H73 Other disorders of tympanic membrane	0.737	0.263
L83 Acanthosis nigricans	0.737	0.263
S69 Other and unspecified injuries of wrist and hand	0.737	0.263
V40-V49 Car occupant injured in transport accident	0.737	0.263
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.735	0.265
M25 Other joint disorders, not elsewhere classified	0.735	0.265
W19 Unspecified fall	0.734	0.266
V80-V89 Other land transport accidents	0.733	0.267
M23.5 Chronic instability of knee	0.731	0.269
Z90.3 Acquired absence of part of stomach	0.730	0.270
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.730	0.270
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.730	0.270
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.730	0.270
S62.60 Fracture of other finger (closed)	0.730	0.270
S90-S99 Injuries to the ankle and foot	0.729	0.271
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.729	0.271
H65.3 Chronic mucoid otitis media	0.728	0.272
Z94 Transplanted organ and tissue status	0.728	0.272
W50-W64 Exposure to animate mechanical forces	0.727	0.273
C43-C44 Melanoma and other malignant neoplasms of skin	0.726	0.274
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.725	0.275
D23.4 Skin of scalp and neck	0.725	0.275
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.725	0.275
X40-X49 Accidental poisoning by and exposure to noxious substances	0.723	0.277
D00-D09 In situ neoplasms	0.722	0.278
Z95 Presence of cardiac and vascular implants and grafts	0.721	0.279
T36-T50 Poisoning by drugs, medicaments and biological substances	0.720	0.279
H66 Suppurative and unspecified otitis media	0.720	0.280
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.720	0.280
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.719	0.280
Z90.2 Acquired absence of lung [part of]	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
D31 Benign neoplasm of eye and adnexa	0.717	0.283
D30 Benign neoplasm of urinary organs	0.717	0.283
D28 Benign neoplasm of other and unspecified female genital organs	0.717	0.283
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.717	0.283
D19 Benign neoplasm of mesothelial tissue	0.717	0.283
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.717	0.283
I00-I02 Acute rheumatic fever	0.716	0.283
I15 Secondary hypertension	0.716	0.284
I13 Hypertensive heart and renal disease	0.716	0.284
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.716	0.284
G35-G37 Demyelinating diseases of the central nervous system	0.716	0.284
D12.1 Appendix	0.716	0.284
Z84 Family history of other conditions	0.715	0.284
Z81 Family history of mental and behavioural disorders	0.715	0.284
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285
M34 Systemic sclerosis	0.715	0.285
M33 Dermatopolymyositis	0.715	0.285
M32 Systemic lupus erythematosus	0.715	0.285
M30 Polyarteritis nodosa and related conditions	0.715	0.285
S64 Injury of nerves at wrist and hand level	0.715	0.285
T75 Effects of other external causes	0.714	0.286
J46 Status asthmaticus	0.714	0.286
C19 Malignant neoplasm of rectosigmoid junction	0.714	0.286
T33-T35 Frostbite	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T20-T25 Burns and corrosions of external body surface, specified by site	0.713	0.287
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
Z97.4 Presence of external hearing-aid	0.713	0.287
D11 Benign neoplasm of major salivary glands	0.713	0.287
Q38-Q45 Other congenital malformations of the digestive system	0.712	0.288
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.712	0.288
H69 Other disorders of Eustachian tube	0.712	0.288
C83.3 Large cell (diffuse)	0.711	0.289
G45 Transient cerebral ischaemic attacks and related syndromes	0.709	0.291
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.708	0.292
M83 Adult osteomalacia	0.708	0.292
M82 Osteoporosis in diseases classified elsewhere	0.708	0.292
D23.1 Skin of eyelid, including canthus	0.707	0.293
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.706	0.294
M23.9 Internal derangement of knee, unspecified	0.706	0.294
M23.6 Other spontaneous disruption of ligament(s) of knee	0.706	0.294
M23.1 Discoid meniscus (congenital)	0.706	0.294
M23.0 Cystic meniscus	0.706	0.294
M45-M49 Spondylopathies	0.706	0.294
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.705	0.295
L90.5 Scar conditions and fibrosis of skin	0.704	0.296
G43.9 Migraine, unspecified	0.704	0.296
D69 Purpura and other haemorrhagic conditions	0.704	0.296
D13.1 Stomach	0.702	0.298
Q60-Q64 Congenital malformations of the urinary system	0.701	0.298
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.701	0.299
L95 Vasculitis limited to skin, not elsewhere classified	0.701	0.299
L72 Follicular cysts of skin and subcutaneous tissue	0.700	0.300
G47.3 Sleep apnoea	0.699	0.301
D26 Other benign neoplasms of uterus	0.698	0.301
I78 Diseases of capillaries	0.698	0.302
Y35-Y36 Legal intervention and operations of war	0.698	0.302
Y10-Y34 Event of undetermined intent	0.698	0.302
Y00-Y09 Assault	0.698	0.302
X85-X99 Assault	0.698	0.302
X58-X59 Accidental exposure to other and unspecified factors	0.698	0.302
X50-X57 Overexertion, travel and privation	0.698	0.302
X30-X39 Exposure to forces of nature	0.698	0.302
X20-X29 Contact with venomous animals and plants	0.698	0.302
X10-X19 Contact with heat and hot substances	0.698	0.302
X00-X09 Exposure to smoke, fire and flames	0.698	0.302
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.698	0.302
W75-W84 Other accidental threats to breathing	0.698	0.302
W65-W74 Accidental drowning and submersion	0.698	0.302
V98-V99 Other and unspecified transport accidents	0.698	0.302
V95-V97 Air and space transport accidents	0.698	0.302
V90-V94 Water transport accidents	0.698	0.302
V70-V79 Bus occupant injured in transport accident	0.698	0.302
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.698	0.302
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.698	0.302
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.698	0.302
V20-V29 Motorcycle rider injured in transport accident	0.698	0.302
V01-V09 Pedestrian injured in transport accident	0.698	0.302
D23.0 Skin of lip	0.698	0.302
M20.0 Deformity of finger(s)	0.697	0.303
Z91 Personal history of risk-factors, not elsewhere classified	0.696	0.304
Q50-Q56 Congenital malformations of genital organs	0.696	0.304
I72 Other aneurysm	0.696	0.304
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.695	0.305
Z80.9 Family history of malignant neoplasm, unspecified	0.694	0.306
L93 Lupus erythematosus	0.694	0.306
T79-T79 Certain early complications of trauma	0.693	0.306
M17 Gonarthrosis [arthrosis of knee]	0.693	0.307
G95 Other diseases of spinal cord	0.693	0.307
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.692	0.308
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.692	0.308
V18 Pedal cyclist injured in noncollision transport accident	0.692	0.308
D36.7 Other specified sites	0.692	0.308
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.691	0.308
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.691	0.309
T78 Adverse effects, not elsewhere classified	0.691	0.309
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.691	0.309
M31 Other necrotising vasculopathies	0.690	0.310
I05 Rheumatic mitral valve diseases	0.689	0.311
G41 Status epilepticus	0.689	0.311
I60 Subarachnoid haemorrhage	0.689	0.311
Z98.0 Intestinal bypass and anastomosis status	0.689	0.311
M81.8 Other osteoporosis	0.688	0.311
M81.6 Localised osteoporosis [Lequesne]	0.688	0.311
M81.5 Idiopathic osteoporosis	0.688	0.311
M81.3 Postsurgical malabsorption osteoporosis	0.688	0.311
M81.2 Osteoporosis of disuse	0.688	0.311
M81.1 Postoophorectomy osteoporosis	0.688	0.311
M81.0 Postmenopausal osteoporosis	0.688	0.311
M14 Arthropathies in other diseases classified elsewhere	0.688	0.312
Z89.4 Acquired absence of foot and ankle	0.688	0.312
S30 Superficial injury of abdomen, lower back and pelvis	0.687	0.313
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.687	0.313
N60 Benign mammary dysplasia	0.687	0.313
E20-E35 Disorders of other endocrine glands	0.686	0.314
M19.90 Arthrosis, unspecified (Multiple sites)	0.685	0.315
Z93 Artificial opening status	0.684	0.316
I20-I25 Ischaemic heart diseases	0.684	0.316
D34 Benign neoplasm of thyroid gland	0.683	0.317
H80 Otosclerosis	0.683	0.317
I68 Cerebrovascular disorders in diseases classified elsewhere	0.683	0.317
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.683	0.317
L90.0 Lichen sclerosus et atrophicus	0.682	0.318
T92.8 Sequelae of other specified injuries of upper limb	0.681	0.319
Chapter V Mental and behavioural disorders	0.681	0.319
N70-N77 Inflammatory diseases of female pelvic organs	0.680	0.320
Q00-Q07 Congenital malformations of the nervous system	0.680	0.320
S62.5 Fracture of thumb	0.679	0.321
T90 Sequelae of injuries of head	0.679	0.321
G90 Disorders of autonomic nervous system	0.678	0.322
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.677	0.323
H68 Eustachian salpingitis and obstruction	0.677	0.323
H67 Otitis media in diseases classified elsewhere	0.677	0.323
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.677	0.323
J45.0 Predominantly allergic asthma	0.677	0.323
Z83 Family history of other specific disorders	0.676	0.323
M05 Seropositive rheumatoid arthritis	0.676	0.324
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.674	0.326
M70-M79 Other soft tissue disorders	0.674	0.326
I69.3 Sequelae of cerebral infarction	0.673	0.327
G46 Vascular syndromes of brain in cerebrovascular diseases	0.673	0.327
G44.8 Other specified headache syndromes	0.672	0.327
S52 Fracture of forearm	0.672	0.328
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.672	0.328
Q80-Q89 Other congenital malformations	0.672	0.328
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.672	0.328
Q35-Q37 Cleft lip and cleft palate	0.672	0.328
Q30-Q34 Congenital malformations of the respiratory system	0.672	0.328
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.672	0.328
D33 Benign neoplasm of brain and other parts of central nervous system	0.672	0.328
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.672	0.328
N30-N39 Other diseases of urinary system	0.672	0.328
H72 Perforation of tympanic membrane	0.671	0.329
G44.2 Tension-type headache	0.671	0.329
M20.3 Other deformity of hallux (acquired)	0.670	0.330
H74 Other disorders of middle ear and mastoid	0.669	0.331
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.669	0.331
M81.96 Osteoporosis, unspecified (Lower leg)	0.669	0.331
M81.94 Osteoporosis, unspecified (Hand)	0.669	0.331
M81.93 Osteoporosis, unspecified (Forearm)	0.669	0.331
M81.92 Osteoporosis, unspecified (Upper arm)	0.669	0.331
M81.91 Osteoporosis, unspecified (Shoulder region)	0.669	0.331
C61 Malignant neoplasm of prostate	0.669	0.331
X60-X84 Intentional self-harm	0.668	0.332
M80.9 Unspecified osteoporosis with pathological fracture	0.668	0.332
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.668	0.332
Z92 Personal history of medical treatment	0.668	0.332
G47.1 Disorders of excessive somnolence [hypersomnias]	0.668	0.332
J80-J84 Other respiratory diseases principally affecting the interstitium	0.668	0.332
D69.3 Idiopathic thrombocytopenic purpura	0.667	0.333
Z85.4 Personal history of malignant neoplasm of genital organs	0.667	0.333
Z90.5 Acquired absence of kidney	0.666	0.334
N03 Chronic nephritic syndrome	0.666	0.334
J44 Other chronic obstructive pulmonary disease	0.666	0.334
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.666	0.334
D13.0 Oesophagus	0.666	0.334
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.666	0.334
C20 Malignant neoplasm of rectum	0.665	0.335
G06 Intracranial and intraspinal abscess and granuloma	0.665	0.335
G80-G83 Cerebral palsy and other paralytic syndromes	0.665	0.335
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.665	0.335
M22.2 Patellofemoral disorders	0.663	0.337
M40-M43 Deforming dorsopathies	0.663	0.337
N99-N99 Other disorders of the genitourinary system	0.662	0.338
C81 Hodgkin's disease	0.662	0.338
T98 Sequelae of other and unspecified effects of external causes	0.661	0.339
T95 Sequelae of burns, corrosions and frostbite	0.661	0.339
T94 Sequelae of injuries involving multiple and unspecified body regions	0.661	0.339
T91 Sequelae of injuries of neck and trunk	0.661	0.339
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.661	0.339
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.661	0.339
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.661	0.339
W08 Fall involving other furniture	0.661	0.339
Z11.0 Special screening examination for intestinal infectious diseases	0.661	0.339
H82 Vertiginous syndromes in diseases classified elsewhere	0.661	0.339
N45 Orchitis and epididymitis	0.661	0.339
Y60-Y69 Misadventures to patients during surgical and medical care	0.659	0.340
S62.0 Fracture of navicular [scaphoid] bone of hand	0.659	0.341
M19.2 Other secondary arthrosis	0.659	0.341
E70-E90 Metabolic disorders	0.658	0.342
I24 Other acute ischaemic heart diseases	0.658	0.342
H65.4 Other chronic nonsuppurative otitis media	0.657	0.343
L89 Decubitus ulcer	0.657	0.343
W07 Fall involving chair	0.657	0.343
M19.0 Primary arthrosis of other joints	0.656	0.344
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.656	0.344
M66 Spontaneous rupture of synovium and tendon	0.656	0.344
Z95.0 Presence of cardiac pacemaker	0.656	0.344
Q27 Other congenital malformations of peripheral vascular system	0.655	0.345
Z03.3 Observation for suspected nervous system disorder	0.654	0.346
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.654	0.346
M65.9 Synovitis and tenosynovitis, unspecified	0.653	0.347
L71 Rosacea	0.653	0.347
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.653	0.347
I73.9 Peripheral vascular disease, unspecified	0.653	0.347
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.652	0.348
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.652	0.348
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.652	0.348
D22.1 Melanocytic naevi of eyelid, including canthus	0.652	0.348
S60 Superficial injury of wrist and hand	0.651	0.349
M85.8 Other specified disorders of bone density and structure	0.651	0.349
Q21 Congenital malformations of cardiac septa	0.651	0.349
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.651	0.349
L94 Other localised connective tissue disorders	0.651	0.349
L87 Transepidermal elimination disorders	0.651	0.349
L88 Pyoderma gangrenosum	0.651	0.349
L86 Keratoderma in diseases classified elsewhere	0.651	0.349
L80 Vitiligo	0.651	0.349
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.650	0.350
Z90.4 Acquired absence of other parts of digestive tract	0.649	0.351
S65 Injury of blood vessels at wrist and hand level	0.649	0.351
M10 Gout	0.649	0.351
J41 Simple and mucopurulent chronic bronchitis	0.649	0.351
D29.1 Prostate	0.649	0.351
N20.1 Calculus of ureter	0.647	0.353
Z97.5 Presence of (intra-uterine) contraceptive device	0.646	0.354
M19.96 Arthrosis, unspecified-Lower leg	0.645	0.355
D35 Benign neoplasm of other and unspecified endocrine glands	0.644	0.356
M23.87 Other internal derangements of knee (Capsular ligament)	0.644	0.356
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.644	0.356
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.644	0.356
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.644	0.356
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.644	0.356
M23.80 Other internal derangements of knee (Multiple sites)	0.644	0.356
D13.9 Ill-defined sites within the digestive system	0.644	0.356
D13.7 Endocrine pancreas	0.644	0.356
D13.6 Pancreas	0.644	0.356
D13.5 Extrahepatic bile ducts	0.644	0.356
D13.4 Liver	0.644	0.356
D13.3 Other and unspecified parts of small intestine	0.644	0.356
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.643	0.357
M12 Other specific arthropathies	0.642	0.357
M09 Juvenile arthritis in diseases classified elsewhere	0.642	0.357
M08 Juvenile arthritis	0.642	0.357
I24.8 Other forms of acute ischaemic heart disease	0.642	0.358
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.642	0.358
D27 Benign neoplasm of ovary	0.642	0.358
C43 Malignant melanoma of skin	0.641	0.359
J60-J70 Lung diseases due to external agents	0.641	0.359
G30-G32 Other degenerative diseases of the nervous system	0.641	0.359
M87 Osteonecrosis	0.641	0.359
L85 Other epidermal thickening	0.640	0.359
C45.0 Mesothelioma of pleura	0.640	0.360
M22.4 Chondromalacia patellae	0.640	0.360
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.640	0.360
D45 Polycythaemia vera	0.639	0.360
G70-G73 Diseases of myoneural junction and muscle	0.639	0.361
S67 Crushing injury of wrist and hand	0.638	0.362
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.638	0.362
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.638	0.362

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations