TreeWAS – Variant ID: rs57582212

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.999	0.001	0.000
E04 Other non-toxic goitre	0.995	0.005	0.000
E04.9 Non-toxic goitre, unspecified	0.988	0.012	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.935	0.065	0.000
E04.2 Non-toxic multinodular goitre	0.932	0.068	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.926	0.074	0.000
E05.9 Thyrotoxicosis, unspecified	0.910	0.090	0.000
J45.9 Asthma, unspecified	0.908	0.092	0.000
M06.9 Rheumatoid arthritis, unspecified	0.889	0.111	0.000
M06 Other rheumatoid arthritis	0.878	0.122	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.875	0.125	0.000
M05-M14 Inflammatory polyarthropathies	0.873	0.127	0.000
J45 Asthma	0.868	0.132	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.858	0.142	0.000
# Top node	0.856	0.144	0.000
M05 Seropositive rheumatoid arthritis	0.856	0.144	0.000
Chapter X Diseases of the respiratory system	0.855	0.145	0.000
J40-J47 Chronic lower respiratory diseases	0.852	0.148	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.844	0.156	0.000
Chapter XX External causes of morbidity and mortality	0.841	0.159	0.000
E10-E14 Diabetes mellitus	0.831	0.169	0.000
E06 Thyroiditis	0.830	0.170	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.826	0.174	0.000
E20-E35 Disorders of other endocrine glands	0.824	0.176	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.807	0.193	0.000
E10 Insulin-dependent diabetes mellitus	0.806	0.194	0.000
J95-J99 Other diseases of the respiratory system	0.796	0.204	0.000
V10-V19 Pedal cyclist injured in transport accident	0.794	0.206	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.785	0.215	0.000
J09-J18 Influenza and pneumonia	0.784	0.216	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.779	0.221	0.000
E10.9 Without complications	0.777	0.223	0.000
S40-S49 Injuries to the shoulder and upper arm	0.777	0.223	0.000
M91-M94 Chondropathies	0.776	0.224	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.773	0.227	0.000
S70-S79 Injuries to the hip and thigh	0.769	0.231	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.769	0.231	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.747	0.253	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.742	0.258	0.000
E07 Other disorders of thyroid	0.738	0.262	0.000
E27 Other disorders of adrenal gland	0.734	0.266	0.000
J98 Other respiratory disorders	0.732	0.268	0.000
M70-M79 Other soft tissue disorders	0.728	0.272	0.000
S10-S19 Injuries to the neck	0.728	0.272	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.723	0.277	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.722	0.278	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.720	0.280	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.718	0.282	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E13 Other specified diabetes mellitus	0.714	0.286	0.000
E04.8 Other specified non-toxic goitre	0.714	0.286	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.713	0.287	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.710	0.290	0.000
M40-M43 Deforming dorsopathies	0.704	0.296	0.000
Chapter XXII Codes for special purposes	0.704	0.296	0.000
E10.2 With renal complications	0.702	0.298	0.000
V18.0 Driver injured in nontraffic accident	0.701	0.299	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.700	0.300	0.000
J42 Unspecified chronic bronchitis	0.698	0.302	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.697	0.303	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.695	0.305	0.000
W50-W64 Exposure to animate mechanical forces	0.694	0.306	0.000
J00-J06 Acute upper respiratory infections	0.694	0.306	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.689	0.311	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.689	0.311	0.000
E04.0 Non-toxic diffuse goitre	0.686	0.314	0.000
E50-E64 Other nutritional deficiencies	0.684	0.316	0.000
V20-V29 Motorcycle rider injured in transport accident	0.684	0.316	0.000
M86-M90 Other osteopathies	0.683	0.317	0.000
J18 Pneumonia, organism unspecified	0.682	0.318	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.682	0.318	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.681	0.319	0.000
J98.1 Pulmonary collapse	0.681	0.319	0.000
Y84.8 Other medical procedures	0.678	0.322	0.000
M06.4 Inflammatory polyarthropathy	0.677	0.323	0.000
M77 Other enthesopathies	0.675	0.325	0.000
J17 Pneumonia in diseases classified elsewhere	0.674	0.326	0.000
T92 Sequelae of injuries of upper limb	0.672	0.328	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.671	0.329	0.000
S72 Fracture of femur	0.670	0.330	0.000
E05.8 Other thyrotoxicosis	0.670	0.330	0.000
E05.5 Thyroid crisis or storm	0.670	0.330	0.000
E05.4 Thyrotoxicosis factitia	0.670	0.330	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.670	0.330	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.670	0.330	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.670	0.330	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.669	0.331	0.000
E27.1 Primary adrenocortical insufficiency	0.668	0.332	0.000
E06.9 Thyroiditis, unspecified	0.667	0.333	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.662	0.338	0.000
S90-S99 Injuries to the ankle and foot	0.657	0.343	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.656	0.344	0.000
M94 Other disorders of cartilage	0.656	0.344	0.000
E06.3 Autoimmune thyroiditis	0.655	0.345	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.655	0.345	0.000
M92 Other juvenile osteochondrosis	0.654	0.346	0.000
Y00-Y09 Assault	0.654	0.346	0.000
E28 Ovarian dysfunction	0.653	0.347	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.653	0.347	0.000
M00-M03 Infectious arthropathies	0.651	0.349	0.000
E03.8 Other specified hypothyroidism	0.648	0.352	0.000
V40-V49 Car occupant injured in transport accident	0.646	0.354	0.000
J18.1 Lobar pneumonia, unspecified	0.645	0.355	0.000
T18 Foreign body in alimentary tract	0.645	0.355	0.000
E10.3 With ophthalmic complications	0.645	0.355	0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.642	0.358	0.000
S12 Fracture of neck	0.642	0.358	0.000
E26 Hyperaldosteronism	0.641	0.359	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.640	0.360	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.638	0.362	0.000
D80-D89 Certain disorders involving the immune mechanism	0.637	0.363	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.636	0.364	0.000
J60-J70 Lung diseases due to external agents	0.636	0.364	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.636	0.364	0.000
X20-X29 Contact with venomous animals and plants	0.634	0.366	0.000
T92.1 Sequelae of fracture of arm	0.634	0.366	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.633	0.367	0.000
T93 Sequelae of injuries of lower limb	0.632	0.368	0.000
E13.9 Without complications	0.630	0.370	0.000
M06.8 Other specified rheumatoid arthritis	0.630	0.370	0.000
M06.2 Rheumatoid bursitis	0.630	0.370	0.000
M06.1 Adult-onset Still's disease	0.630	0.370	0.000
S40 Superficial injury of shoulder and upper arm	0.627	0.373	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.626	0.374	0.000
M12 Other specific arthropathies	0.626	0.374	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.626	0.374	0.000
M08 Juvenile arthritis	0.626	0.374	0.000
M77.9 Enthesopathy, unspecified	0.625	0.375	0.000
J45.8 Mixed asthma	0.623	0.377	0.000
J45.1 Nonallergic asthma	0.623	0.377	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.618	0.382	0.000
T00-T07 Injuries involving multiple body regions	0.618	0.382	0.000
E40-E46 Malnutrition	0.618	0.382	0.000
J02 Acute pharyngitis	0.618	0.382	0.000
E27.9 Disorder of adrenal gland, unspecified	0.616	0.384	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.614	0.386	0.000
M05.8 Other seropositive rheumatoid arthritis	0.613	0.386	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.613	0.386	0.000
M05.2 Rheumatoid vasculitis	0.613	0.386	0.000
M05.1 Rheumatoid lung disease	0.613	0.386	0.000
M05.0 Felty's syndrome	0.613	0.386	0.000
Y84.2 Radiological procedure and radiotherapy	0.612	0.388	0.000
J41 Simple and mucopurulent chronic bronchitis	0.611	0.389	0.000
S79 Other and unspecified injuries of hip and thigh	0.610	0.390	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.609	0.391	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.608	0.392	0.000
T14 Injury of unspecified body region	0.608	0.392	0.000
S41 Open wound of shoulder and upper arm	0.607	0.393	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.605	0.395	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.605	0.395	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.605	0.395	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.605	0.395	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.605	0.395	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.605	0.395	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.605	0.395	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.605	0.395	0.000
E24 Cushing's syndrome	0.604	0.396	0.000
Y35-Y36 Legal intervention and operations of war	0.603	0.397	0.000
Y10-Y34 Event of undetermined intent	0.603	0.397	0.000
X85-X99 Assault	0.603	0.397	0.000
X30-X39 Exposure to forces of nature	0.603	0.397	0.000
X10-X19 Contact with heat and hot substances	0.603	0.397	0.000
X00-X09 Exposure to smoke, fire and flames	0.603	0.397	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.603	0.397	0.000
W75-W84 Other accidental threats to breathing	0.603	0.397	0.000
W65-W74 Accidental drowning and submersion	0.603	0.397	0.000
V98-V99 Other and unspecified transport accidents	0.603	0.397	0.000
V95-V97 Air and space transport accidents	0.603	0.397	0.000
V90-V94 Water transport accidents	0.603	0.397	0.000
V70-V79 Bus occupant injured in transport accident	0.603	0.397	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.603	0.397	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.603	0.397	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.603	0.397	0.000
V01-V09 Pedestrian injured in transport accident	0.603	0.397	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.602	0.398	0.000
S70 Superficial injury of hip and thigh	0.601	0.399	0.000
T13 Other injuries of lower limb, level unspecified	0.601	0.399	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.600	0.400	0.000
J98.4 Other disorders of lung	0.599	0.401	0.000
E34 Other endocrine disorders	0.599	0.401	0.000
W00-W19 Falls	0.599	0.401	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.596	0.404	0.000
E20 Hypoparathyroidism	0.596	0.404	0.000
E12 Malnutrition-related diabetes mellitus	0.596	0.404	0.000
E06.5 Other chronic thyroiditis	0.595	0.405	0.000
E06.4 Drug-induced thyroiditis	0.595	0.405	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.595	0.405	0.000
E06.1 Subacute thyroiditis	0.595	0.405	0.000
E06.0 Acute thyroiditis	0.595	0.405	0.000
S37 Injury of urinary and pelvic organs	0.594	0.406	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.594	0.406	0.000
M11 Other crystal arthropathies	0.592	0.408	0.000
M75 Shoulder lesions	0.592	0.408	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.592	0.408	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.591	0.409	0.000
E32 Diseases of thymus	0.591	0.409	0.000
E31 Polyglandular dysfunction	0.591	0.409	0.000
E30 Disorders of puberty, not elsewhere classified	0.591	0.409	0.000
E25 Adrenogenital disorders	0.591	0.409	0.000
J10 Influenza due to identified influenza virus	0.590	0.410	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.589	0.411	0.000
M75.0 Adhesive capsulitis of shoulder	0.589	0.411	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.589	0.411	0.000
J40 Bronchitis, not specified as acute or chronic	0.587	0.413	0.000
M14 Arthropathies in other diseases classified elsewhere	0.586	0.413	0.000
S36 Injury of intra-abdominal organs	0.586	0.414	0.000
M60-M63 Disorders of muscles	0.586	0.414	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.585	0.415	0.000
M93 Other osteochondropathies	0.584	0.416	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.583	0.417	0.000
S92 Fracture of foot, except ankle	0.579	0.421	0.000
T33-T35 Frostbite	0.579	0.421	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.579	0.421	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.579	0.421	0.000
E10.8 With unspecified complications	0.578	0.422	0.000
E10.7 With multiple complications	0.578	0.422	0.000
E10.6 With other specified complications	0.578	0.422	0.000
E10.0 With coma	0.578	0.422	0.000
E10.1 With ketoacidosis	0.575	0.425	0.000
J14 Pneumonia due to Haemophilus influenzae	0.575	0.425	0.000
J17.3 Pneumonia in parasitic diseases	0.575	0.425	0.000
J98.6 Disorders of diaphragm	0.575	0.425	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.574	0.426	0.000
J98.9 Respiratory disorder, unspecified	0.574	0.426	0.000
S10 Superficial injury of neck	0.572	0.428	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.571	0.429	0.000
W20-W49 Exposure to inanimate mechanical forces	0.571	0.429	0.000
J96 Respiratory failure, not elsewhere classified	0.571	0.429	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.570	0.430	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.569	0.431	0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.569	0.431	0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.569	0.431	0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.569	0.431	0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.569	0.431	0.000
V11 Pedal cyclist injured in collision with other pedal cycle	0.569	0.431	0.000
V10 Pedal cyclist injured in collision with pedestrian or animal	0.569	0.431	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.569	0.431	0.000
V80-V89 Other land transport accidents	0.567	0.433	0.000
S72.3 Fracture of shaft of femur	0.566	0.433	0.000
T98 Sequelae of other and unspecified effects of external causes	0.566	0.434	0.000
S71 Open wound of hip and thigh	0.565	0.435	0.000
M94.8 Other specified disorders of cartilage	0.564	0.436	0.000
E07.8 Other specified disorders of thyroid	0.564	0.436	0.000
J02.9 Acute pharyngitis, unspecified	0.563	0.437	0.000
S72.0 Fracture of neck of femur	0.563	0.437	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.562	0.438	0.000
J12 Viral pneumonia, not elsewhere classified	0.562	0.438	0.000
J09 Influenza due to certain identified influenza virus	0.562	0.438	0.000
V28 Motorcycle rider injured in noncollision transport accident	0.561	0.439	0.000
S12.1 Fracture of second cervical vertebra	0.561	0.439	0.000
M07 Psoriatic and enteropathic arthropathies	0.560	0.440	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.559	0.441	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.559	0.441	0.000
X50-X57 Overexertion, travel and privation	0.557	0.442	0.000
T18.1 Foreign body in oesophagus	0.557	0.443	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.557	0.443	0.000
S48 Traumatic amputation of shoulder and upper arm	0.557	0.443	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.557	0.443	0.000
S44 Injury of nerves at shoulder and upper arm level	0.557	0.443	0.000
S47 Crushing injury of shoulder and upper arm	0.557	0.443	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.556	0.443	0.000
M06.3 Rheumatoid nodule	0.556	0.444	0.000
M41 Scoliosis	0.555	0.445	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.555	0.445	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.554	0.446	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.554	0.446	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.554	0.446	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.554	0.446	0.000
S31 Open wound of abdomen, lower back and pelvis	0.554	0.446	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.554	0.446	0.000
E23 Hypofunction and other disorders of pituitary gland	0.554	0.446	0.000
J04 Acute laryngitis and tracheitis	0.554	0.446	0.000
M06.0 Seronegative rheumatoid arthritis	0.552	0.448	0.000
S78 Traumatic amputation of hip and thigh	0.552	0.448	0.000
S77 Crushing injury of hip and thigh	0.552	0.448	0.000
S75 Injury of blood vessels at hip and thigh level	0.552	0.448	0.000
S74 Injury of nerves at hip and thigh level	0.552	0.448	0.000
S30.0 Contusion of lower back and pelvis	0.551	0.449	0.000
M80-M85 Disorders of bone density and structure	0.550	0.450	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.550	0.450	0.000
E04.1 Non-toxic single thyroid nodule	0.549	0.451	0.000
X60-X84 Intentional self-harm	0.549	0.451	0.000
S73.0 Dislocation of hip	0.548	0.452	0.000
M90 Osteopathies in diseases classified elsewhere	0.547	0.453	0.000
E10.4 With neurological complications	0.546	0.453	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.543	0.456	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.543	0.457	0.000
Y86 Sequelae of other accidents	0.542	0.458	0.000
D86 Sarcoidosis	0.540	0.460	0.000
M43 Other deforming dorsopathies	0.539	0.461	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.538	0.462	0.000
M76 Enthesopathies of lower limb, excluding foot	0.538	0.462	0.000
E53 Deficiency of other B group vitamins	0.537	0.462	0.000
V14.4 Driver injured in traffic accident	0.533	0.467	0.000
D69 Purpura and other haemorrhagic conditions	0.533	0.467	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.533	0.467	0.000
S32 Fracture of lumbar spine and pelvis	0.532	0.468	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.532	0.468	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.532	0.468	0.000
V18.4 Driver injured in traffic accident	0.532	0.468	0.000
V18.5 Passenger injured in traffic accident	0.532	0.468	0.000
V18.3 Person injured while boarding or alighting	0.532	0.468	0.000
V18.1 Passenger injured in nontraffic accident	0.532	0.468	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.532	0.468	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.531	0.469	0.000
Chapter VIII Diseases of the ear and mastoid process	0.531	0.469	0.000
E28.2 Polycystic ovarian syndrome	0.530	0.469	0.000
E29 Testicular dysfunction	0.530	0.470	0.000
E07.1 Dyshormogenetic goitre	0.529	0.471	0.000
E07.0 Hypersecretion of calcitonin	0.529	0.471	0.000
E65-E68 Obesity and other hyperalimentation	0.527	0.472	0.000
Chapter VI Diseases of the nervous system	0.526	0.474	0.000
E27.5 Adrenomedullary hyperfunction	0.526	0.474	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.526	0.474	0.000
E27.2 Addisonian crisis	0.526	0.474	0.000
E27.0 Other adrenocortical overactivity	0.526	0.474	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.525	0.474	0.001
S19 Other and unspecified injuries of neck	0.526	0.474	0.000
J98.3 Compensatory emphysema	0.525	0.475	0.000
J98.2 Interstitial emphysema	0.525	0.475	0.000
M40 Kyphosis and lordosis	0.524	0.476	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.524	0.476	0.000
S72.1 Pertrochanteric fracture	0.524	0.476	0.000
M77.5 Other enthesopathy of foot	0.524	0.476	0.000
J17.2 Pneumonia in mycoses	0.524	0.476	0.000
J01 Acute sinusitis	0.524	0.476	0.000
V43 Car occupant injured in collision with car, pick-up truck or van	0.523	0.477	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.523	0.477	0.000
S42 Fracture of shoulder and upper arm	0.522	0.478	0.000
M88 Paget's disease of bone [osteitis deformans]	0.522	0.478	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.522	0.478	0.000
S17 Crushing injury of neck	0.522	0.478	0.000
S15 Injury of blood vessels at neck level	0.522	0.478	0.000
S14 Injury of nerves and spinal cord at neck level	0.522	0.478	0.000
S11 Open wound of neck	0.522	0.478	0.000
S18 Traumatic amputation at neck level	0.522	0.478	0.000
S16 Injury of muscle and tendon at neck level	0.522	0.478	0.000
E21.0 Primary hyperparathyroidism	0.522	0.478	0.000
M10 Gout	0.520	0.480	0.000
Y00 Assault by blunt object	0.519	0.481	0.000
W07 Fall involving chair	0.519	0.481	0.000
T95 Sequelae of burns, corrosions and frostbite	0.519	0.481	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.519	0.481	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.519	0.481	0.000
J64 Unspecified pneumoconiosis	0.518	0.482	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.516	0.484	0.000
T11 Other injuries of upper limb, level unspecified	0.515	0.485	0.000
T09 Other injuries of spine and trunk, level unspecified	0.515	0.485	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.515	0.485	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.515	0.485	0.000
T12 Fracture of lower limb, level unspecified	0.515	0.485	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.515	0.485	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.515	0.485	0.000
T10 Fracture of upper limb, level unspecified	0.515	0.485	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.515	0.485	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.515	0.485	0.000
T08 Fracture of spine, level unspecified	0.515	0.485	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.514	0.486	0.000
T79-T79 Certain early complications of trauma	0.513	0.487	0.000
E61 Deficiency of other nutrient elements	0.513	0.487	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.513	0.487	0.000
Y89 Sequelae of other external causes	0.512	0.488	0.000
E07.9 Disorder of thyroid, unspecified	0.512	0.488	0.000
T18.5 Foreign body in anus and rectum	0.512	0.488	0.000
E13.8 With unspecified complications	0.512	0.488	0.000
E13.7 With multiple complications	0.512	0.488	0.000
E13.6 With other specified complications	0.512	0.488	0.000
E13.5 With peripheral circulatory complications	0.512	0.488	0.000
E13.4 With neurological complications	0.512	0.488	0.000
E13.3 With ophthalmic complications	0.512	0.488	0.000
E13.2 With renal complications	0.512	0.488	0.000
E13.1 With ketoacidosis	0.512	0.488	0.000
E13.0 With coma	0.512	0.488	0.000
Y85 Sequelae of transport accidents	0.511	0.489	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.511	0.489	0.000
E26.0 Primary hyperaldosteronism	0.510	0.490	0.000
U89 Agent resistant to other and unspecified antibiotics	0.510	0.490	0.000
S92.0 Fracture of calcaneus	0.510	0.490	0.000
T19 Foreign body in genito-urinary tract	0.509	0.491	0.000
T15 Foreign body on external eye	0.509	0.491	0.000
T16 Foreign body in ear	0.509	0.491	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.509	0.491	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.509	0.491	0.000
W06 Fall involving bed	0.509	0.491	0.000
M77.0 Medial epicondylitis	0.509	0.491	0.000
T92.0 Sequelae of open wound of upper limb	0.508	0.492	0.000
J15.2 Pneumonia due to staphylococcus	0.507	0.493	0.000
W50.9 Unspecified place	0.506	0.493	0.000
J43 Emphysema	0.506	0.494	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.505	0.495	0.000
M87 Osteonecrosis	0.505	0.495	0.000
M42 Spinal osteochondrosis	0.504	0.495	0.000
M94.88 Other specified disorders of cartilage (Other)	0.505	0.495	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.504	0.496	0.000
S99 Other and unspecified injuries of ankle and foot	0.503	0.497	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.503	0.497	0.000
M00 Pyogenic arthritis	0.502	0.497	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.500	0.500	0.000
J11 Influenza, virus not identified	0.500	0.500	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.500	0.500	0.000
S30.2 Contusion of external genital organs	0.500	0.500	0.000
T13.1 Open wound of lower limb, level unspecified	0.500	0.500	0.000
T93.1 Sequelae of fracture of femur	0.500	0.500	0.000
S90 Superficial injury of ankle and foot	0.499	0.500	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.498	0.502	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.498	0.502	0.000
W59 Bitten or crushed by other reptiles	0.498	0.502	0.000
W58 Bitten or struck by crocodile or alligator	0.498	0.502	0.000
W56 Contact with marine animal	0.498	0.502	0.000
W54 Bitten or struck by dog	0.498	0.502	0.000
W53 Bitten by rat	0.498	0.502	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.498	0.502	0.000
W51 Striking against or bumped into by another person	0.498	0.502	0.000
S79.9 Unspecified injury of hip and thigh	0.496	0.504	0.000
S30.1 Contusion of abdominal wall	0.496	0.504	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.496	0.504	0.000
T17 Foreign body in respiratory tract	0.495	0.505	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.494	0.506	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.494	0.506	0.000
Y84.9 Medical procedure, unspecified	0.494	0.506	0.000
Y84.7 Blood-sampling	0.494	0.506	0.000
Y84.5 Insertion of gastric or duodenal sound	0.494	0.506	0.000
Y84.4 Aspiration of fluid	0.494	0.506	0.000
Y84.3 Shock therapy	0.494	0.506	0.000
S72.30 Fracture of shaft of femur (closed)	0.492	0.508	0.000
T14.0 Superficial injury of unspecified body region	0.491	0.509	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.491	0.509	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.490	0.510	0.000
E63 Other nutritional deficiencies	0.490	0.510	0.000
E56 Other vitamin deficiencies	0.490	0.510	0.000
E51 Thiamine deficiency	0.490	0.510	0.000
E50 Vitamin A deficiency	0.490	0.510	0.000
E60 Dietary zinc deficiency	0.490	0.510	0.000
E59 Dietary selenium deficiency	0.490	0.510	0.000
E58 Dietary calcium deficiency	0.490	0.510	0.000
E54 Ascorbic acid deficiency	0.490	0.510	0.000
E52 Niacin deficiency [pellagra]	0.490	0.510	0.000
M86 Osteomyelitis	0.490	0.510	0.000
V29 Motorcycle rider injured in other and unspecified transport accidents	0.490	0.510	0.000
V27 Motorcycle rider injured in collision with fixed or stationary object	0.490	0.510	0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle	0.490	0.510	0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle	0.490	0.510	0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus	0.490	0.510	0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle	0.490	0.510	0.000
V21 Motorcycle rider injured in collision with pedal cycle	0.490	0.510	0.000
V20 Motorcycle rider injured in collision with pedestrian or animal	0.490	0.510	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.489	0.510	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.489	0.511	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.489	0.511	0.000
S12.2 Fracture of other specified cervical vertebra	0.489	0.511	0.000
J18.8 Other pneumonia, organism unspecified	0.489	0.511	0.000
J18.2 Hypostatic pneumonia, unspecified	0.489	0.511	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.489	0.511	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.489	0.511	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.488	0.511	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.488	0.511	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.488	0.511	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.488	0.511	0.000
M94.9 Disorder of cartilage, unspecified	0.488	0.512	0.000
T14.9 Injury, unspecified	0.487	0.513	0.000
S72.00 Fracture of neck of femur (closed)	0.486	0.514	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.486	0.514	0.000
J90-J94 Other diseases of pleura	0.486	0.514	0.000
S41.1 Open wound of upper arm	0.486	0.514	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.485	0.514	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.485	0.514	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.485	0.514	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.485	0.514	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.485	0.514	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.485	0.514	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.485	0.514	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.485	0.514	0.000
J18.0 Bronchopneumonia, unspecified	0.485	0.515	0.000
X23 Contact with hornets, wasps and bees	0.485	0.515	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.484	0.516	0.000
M77.3 Calcaneal spur	0.484	0.516	0.000
M77.2 Periarthritis of wrist	0.484	0.516	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.483	0.516	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.483	0.516	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.483	0.516	0.000
J00 Acute nasopharyngitis [common cold]	0.483	0.517	0.000
D86.9 Sarcoidosis, unspecified	0.483	0.517	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations