TreeWAS – Variant ID: rs59355858

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
O60-O75 Complications of labour and delivery	1.000	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	1.000	0.000
Chapter II Neoplasms	0.999	0.001
Chapter IV Endocrine, nutritional and metabolic diseases	0.996	0.004
O68 Labour and delivery complicated by foetal stress [distress]	0.993	0.007
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.982	0.018
E00-E07 Disorders of thyroid gland	0.982	0.018
O72 Postpartum haemorrhage	0.980	0.020
E05 Thyrotoxicosis [hyperthyroidism]	0.977	0.023
E05.0 Thyrotoxicosis with diffuse goitre	0.976	0.024
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.975	0.025
T36-T50 Poisoning by drugs, medicaments and biological substances	0.970	0.030
S40-S49 Injuries to the shoulder and upper arm	0.967	0.033
C90 Multiple myeloma and malignant plasma cell neoplasms	0.965	0.035
T20-T25 Burns and corrosions of external body surface, specified by site	0.963	0.037
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.958	0.042
O63 Long labour	0.958	0.042
O72.0 Third-stage haemorrhage	0.955	0.045
E20-E35 Disorders of other endocrine glands	0.953	0.047
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.939	0.061
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.936	0.064
Chapter V Mental and behavioural disorders	0.931	0.069
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.927	0.073
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.926	0.074
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.924	0.076
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.922	0.078
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.920	0.080
C90.0 Multiple myeloma	0.916	0.084
D37-D48 Neoplasms of uncertain or unknown behaviour	0.911	0.089
O34 Maternal care for known or suspected abnormality of pelvic organs	0.911	0.089
C85.1 B-cell lymphoma, unspecified	0.909	0.091
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.909	0.091
E24 Cushing's syndrome	0.904	0.096
O63.1 Prolonged second stage (of labour)	0.904	0.096
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.903	0.097
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.899	0.101
C83 Diffuse non-Hodgkin's lymphoma	0.895	0.105
O48 Prolonged pregnancy	0.895	0.105
C77.8 Lymph nodes of multiple regions	0.893	0.107
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.892	0.108
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.892	0.108
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.889	0.111
S42 Fracture of shoulder and upper arm	0.889	0.111
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.887	0.113
F10 Mental and behavioural disorders due to use of alcohol	0.883	0.117
D00-D09 In situ neoplasms	0.881	0.119
F10.0 Acute intoxication	0.877	0.123
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.876	0.124
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.875	0.125
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.872	0.128
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.872	0.128
O34.2 Maternal care due to uterine scar from previous surgery	0.872	0.128
O72.1 Other immediate postpartum haemorrhage	0.872	0.128
Q20-Q28 Congenital malformations of the circulatory system	0.870	0.130
T51 Toxic effect of alcohol	0.868	0.132
S90-S99 Injuries to the ankle and foot	0.868	0.132
C91 Lymphoid leukaemia	0.865	0.135
S60-S69 Injuries to the wrist and hand	0.859	0.141
C77.9 Lymph node, unspecified	0.857	0.143
C85.7 Other specified types of non-Hodgkin's lymphoma	0.856	0.144
C77.3 Axillary and upper limb lymph nodes	0.854	0.146
Chapter XX External causes of morbidity and mortality	0.852	0.148
C81 Hodgkin's disease	0.848	0.152
Chapter I Certain infectious and parasitic diseases	0.846	0.154
T42.4 Benzodiazepines	0.844	0.156
S68 Traumatic amputation of wrist and hand	0.841	0.159
E06 Thyroiditis	0.839	0.161
T51.0 Ethanol	0.838	0.162
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.837	0.163
O32 Maternal care for known or suspected malpresentation of foetus	0.835	0.165
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.834	0.166
O65 Obstructed labour due to maternal pelvic abnormality	0.831	0.169
O94-O99 Other obstetric conditions, not elsewhere classified	0.831	0.169
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.829	0.171
T92 Sequelae of injuries of upper limb	0.825	0.175
T21 Burn and corrosion of trunk	0.823	0.177
S42.0 Fracture of clavicle	0.817	0.183
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.817	0.183
F80-F89 Disorders of psychological development	0.816	0.184
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.813	0.187
T00-T07 Injuries involving multiple body regions	0.812	0.188
O63.0 Prolonged first stage (of labour)	0.810	0.190
E16 Other disorders of pancreatic internal secretion	0.810	0.190
E24.9 Cushing's syndrome, unspecified	0.805	0.195
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.804	0.196
S49 Other and unspecified injuries of shoulder and upper arm	0.803	0.197
S20-S29 Injuries to the thorax	0.802	0.198
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.800	0.200
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.798	0.202
T14 Injury of unspecified body region	0.797	0.203
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.787	0.213
E27 Other disorders of adrenal gland	0.786	0.214
C76 Malignant neoplasm of other and ill-defined sites	0.785	0.215
D46 Myelodysplastic syndromes	0.784	0.216
S42.7 Multiple fractures of clavicle, scapula and humerus	0.784	0.216
S91 Open wound of ankle and foot	0.780	0.220
C90.1 Plasma cell leukaemia	0.777	0.223
E70-E90 Metabolic disorders	0.777	0.223
O69 Labour and delivery complicated by umbilical cord complications	0.777	0.223
Q23 Congenital malformations of aortic and mitral valves	0.775	0.225
T66-T78 Other and unspecified effects of external causes	0.774	0.226
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.774	0.226
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.774	0.226
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.773	0.227
C71 Malignant neoplasm of brain	0.771	0.229
A00-A09 Intestinal infectious diseases	0.770	0.230
D05 Carcinoma in situ of breast	0.767	0.233
S42.00 Fracture of clavicle (closed)	0.766	0.234
Q60-Q64 Congenital malformations of the urinary system	0.765	0.235
S46 Injury of muscle and tendon at shoulder and upper arm level	0.764	0.236
W20-W49 Exposure to inanimate mechanical forces	0.762	0.238
T92.0 Sequelae of open wound of upper limb	0.762	0.238
C90.2 Plasmacytoma, extramedullary	0.762	0.238
O35 Maternal care for known or suspected foetal abnormality and damage	0.760	0.240
T23 Burn and corrosion of wrist and hand	0.760	0.240
A50-A64 Infections with a predominantly sexual mode of transmission	0.760	0.240
O30 Multiple gestation	0.758	0.242
C77.1 Intrathoracic lymph nodes	0.757	0.243
S41 Open wound of shoulder and upper arm	0.756	0.244
C92 Myeloid leukaemia	0.756	0.244
T90 Sequelae of injuries of head	0.755	0.245
E16.2 Hypoglycaemia, unspecified	0.754	0.246
E29 Testicular dysfunction	0.754	0.246
E24.0 Pituitary-dependent Cushing's disease	0.753	0.247
O20-O29 Other maternal disorders predominantly related to pregnancy	0.753	0.247
S42.1 Fracture of scapula	0.752	0.248
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.751	0.249
S10-S19 Injuries to the neck	0.751	0.249
D55-D59 Haemolytic anaemias	0.751	0.249
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.750	0.250
E24.2 Drug-induced Cushing's syndrome	0.750	0.250
O46 Antepartum haemorrhage, not elsewhere classified	0.750	0.250
Chapter XXII Codes for special purposes	0.748	0.252
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.748	0.252
C40-C41 Malignant neoplasms of bone and articular cartilage	0.747	0.253
T95 Sequelae of burns, corrosions and frostbite	0.745	0.255
O61 Failed induction of labour	0.745	0.255
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.744	0.256
T46 Poisoning by agents primarily affecting the cardiovascular system	0.744	0.256
E06.3 Autoimmune thyroiditis	0.743	0.257
F80 Specific developmental disorders of speech and language	0.741	0.259
T58 Toxic effect of carbon monoxide	0.741	0.259
E22 Hyperfunction of pituitary gland	0.740	0.260
C84 Peripheral and cutaneous T-cell lymphomas	0.739	0.260
Y60-Y69 Misadventures to patients during surgical and medical care	0.739	0.261
C82.0 Small cleaved cell, follicular	0.738	0.262
D05.1 Intraductal carcinoma in situ	0.737	0.263
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.734	0.266
T20 Burn and corrosion of head and neck	0.734	0.266
A04 Other bacterial intestinal infections	0.732	0.268
V10-V19 Pedal cyclist injured in transport accident	0.731	0.269
D68 Other coagulation defects	0.730	0.270
C81.1 Nodular sclerosis	0.729	0.271
T31 Burns classified according to extent of body surface involved	0.720	0.280
O66 Other obstructed labour	0.719	0.281
O73 Retained placenta and membranes, without haemorrhage	0.719	0.281
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
O74 Complications of anaesthesia during labour and delivery	0.717	0.283
O60 Preterm delivery	0.717	0.283
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.717	0.283
C95 Leukaemia of unspecified cell type	0.717	0.283
C94 Other leukaemias of specified cell type	0.717	0.283
C93 Monocytic leukaemia	0.717	0.283
C86 Other specified types of T/NK-cell lymphoma	0.717	0.283
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.716	0.284
O64 Obstructed labour due to malposition and malpresentation of foetus	0.716	0.284
O85-O92 Complications predominantly related to the puerperium	0.715	0.284
T56 Toxic effect of metals	0.715	0.285
E07 Other disorders of thyroid	0.714	0.286
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.714	0.286
E50-E64 Other nutritional deficiencies	0.713	0.286
C83.1 Small cleaved cell (diffuse)	0.712	0.288
T98 Sequelae of other and unspecified effects of external causes	0.711	0.289
T21.2 Burn of second degree of trunk	0.711	0.289
Q24 Other congenital malformations of heart	0.711	0.289
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.711	0.289
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.710	0.290
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.709	0.291
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.709	0.291
S70-S79 Injuries to the hip and thigh	0.709	0.291
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.708	0.291
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.708	0.292
Q28 Other congenital malformations of circulatory system	0.708	0.292
C91.9 Lymphoid leukaemia, unspecified	0.707	0.293
S90 Superficial injury of ankle and foot	0.706	0.294
T15-T19 Effects of foreign body entering through natural orifice	0.705	0.295
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.704	0.296
C85.0 Lymphosarcoma	0.704	0.296
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.704	0.296
E00 Congenital iodine-deficiency syndrome	0.704	0.296
E02 Subclinical iodine-deficiency hypothyroidism	0.704	0.296
D07 Carcinoma in situ of other and unspecified genital organs	0.704	0.296
W22 Striking against or struck by other objects	0.703	0.297
O72.3 Postpartum coagulation defects	0.703	0.297
T11 Other injuries of upper limb, level unspecified	0.701	0.299
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.700	0.299
E05.8 Other thyrotoxicosis	0.700	0.300
E05.5 Thyroid crisis or storm	0.700	0.300
E05.4 Thyrotoxicosis factitia	0.700	0.300
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.700	0.300
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.700	0.300
O44 Placenta praevia	0.700	0.300
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.699	0.301
C82.6 Cutaneous follicle centre lymphoma	0.699	0.301
C82.5 Diffuse follicle centre lymphoma	0.699	0.301
C82.4 Follicular lymphoma grade IIIb	0.699	0.301
C82.3 Follicular lymphoma grade IIIa	0.699	0.301
C82.2 Large cell, follicular	0.699	0.301
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.698	0.302
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.695	0.304
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.695	0.304
T41 Poisoning by anaesthetics and therapeutic gases	0.695	0.304
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.695	0.304
S48 Traumatic amputation of shoulder and upper arm	0.693	0.307
S45 Injury of blood vessels at shoulder and upper arm level	0.693	0.307
S44 Injury of nerves at shoulder and upper arm level	0.693	0.307
S47 Crushing injury of shoulder and upper arm	0.693	0.307
O41 Other disorders of amniotic fluid and membranes	0.693	0.307
D46.9 Myelodysplastic syndrome, unspecified	0.693	0.307
O33 Maternal care for known or suspected disproportion	0.693	0.307
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.692	0.308
C90.3 Solitary plasmacytoma	0.692	0.308
T09 Other injuries of spine and trunk, level unspecified	0.691	0.309
C91.1 Chronic lymphocytic leukaemia	0.691	0.309
T14.0 Superficial injury of unspecified body region	0.691	0.309
T25 Burn and corrosion of ankle and foot	0.691	0.309
E85 Amyloidosis	0.690	0.310
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.690	0.310
X60-X84 Intentional self-harm	0.689	0.311
T94 Sequelae of injuries involving multiple and unspecified body regions	0.689	0.311
F80.1 Expressive language disorder	0.688	0.312
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.688	0.312
C91.4 Hairy-cell leukaemia	0.688	0.312
O31 Complications specific to multiple gestation	0.687	0.313
O63.2 Delayed delivery of second twin, triplet, etc.	0.687	0.313
T63 Toxic effect of contact with venomous animals	0.687	0.313
S49.9 Unspecified injury of shoulder and upper arm	0.686	0.314
F12 Mental and behavioural disorders due to use of cannabinoids	0.686	0.314
A04.8 Other specified bacterial intestinal infections	0.685	0.315
O32.0 Maternal care for unstable lie	0.684	0.315
Q23.1 Congenital insufficiency of aortic valve	0.684	0.316
E35 Disorders of endocrine glands in diseases classified elsewhere	0.683	0.316
E32 Diseases of thymus	0.683	0.316
E31 Polyglandular dysfunction	0.683	0.316
E30 Disorders of puberty, not elsewhere classified	0.683	0.316
E25 Adrenogenital disorders	0.683	0.316
E20 Hypoparathyroidism	0.683	0.316
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.683	0.317
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.683	0.317
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.682	0.318
C71.9 Brain, unspecified	0.681	0.319
O63.9 Long labour, unspecified	0.681	0.319
C83.3 Large cell (diffuse)	0.680	0.320
O32.2 Maternal care for transverse and oblique lie	0.679	0.321
E34 Other endocrine disorders	0.679	0.321
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.679	0.321
O71 Other obstetric trauma	0.679	0.321
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.679	0.321
D04 Carcinoma in situ of skin	0.678	0.321
O45 Premature separation of placenta [abruptio placentae]	0.678	0.322
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.678	0.322
O34.7 Maternal care for abnormality of vulva and perineum	0.678	0.322
S31 Open wound of abdomen, lower back and pelvis	0.677	0.323
D50-D53 Nutritional anaemias	0.677	0.323
F10.1 Harmful use	0.675	0.325
C83.0 Small cell (diffuse)	0.675	0.325
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.675	0.325
T36 Poisoning by systemic antibiotics	0.674	0.326
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.674	0.326
A15-A19 Tuberculosis	0.674	0.326
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.674	0.326
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.672	0.328
T65 Toxic effect of other and unspecified substances	0.671	0.329
T62 Toxic effect of other noxious substances eaten as food	0.671	0.329
T61 Toxic effect of noxious substances eaten as seafood	0.671	0.329
T60 Toxic effect of pesticides	0.671	0.329
T57 Toxic effect of other inorganic substances	0.671	0.329
T54 Toxic effect of corrosive substances	0.671	0.329
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.671	0.329
T52 Toxic effect of organic solvents	0.671	0.329
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.671	0.329
T55 Toxic effect of soaps and detergents	0.671	0.329
O20 Haemorrhage in early pregnancy	0.671	0.329
S91.1 Open wound of toe(s) without damage to nail	0.670	0.330
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.670	0.330
O75 Other complications of labour and delivery, not elsewhere classified	0.669	0.331
C82.1 Mixed small cleaved and large cell, follicular	0.668	0.332
A04.7 Enterocolitis due to Clostridium difficile	0.668	0.332
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.667	0.332
F70-F79 Mental retardation	0.667	0.332
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.666	0.334
C88 Malignant immunoproliferative diseases	0.666	0.334
C77.4 Inguinal and lower limb lymph nodes	0.665	0.335
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.664	0.336
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.664	0.336
O67.9 Intrapartum haemorrhage, unspecified	0.664	0.336
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.663	0.336
S22 Fracture of rib(s), sternum and thoracic spine	0.663	0.337
D02 Carcinoma in situ of middle ear and respiratory system	0.662	0.338
T92.4 Sequelae of injury of nerve of upper limb	0.661	0.339
W50-W64 Exposure to animate mechanical forces	0.660	0.340
F10.3 Withdrawal state	0.660	0.340
O34.8 Maternal care for other abnormalities of pelvic organs	0.660	0.340
B25-B34 Other viral diseases	0.660	0.340
S40 Superficial injury of shoulder and upper arm	0.660	0.340
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.660	0.340
Q35-Q37 Cleft lip and cleft palate	0.660	0.340
Q30-Q34 Congenital malformations of the respiratory system	0.660	0.340
O34.1 Maternal care for tumour of corpus uteri	0.660	0.340
F99-F99 Unspecified mental disorder	0.660	0.340
T40.6 Other and unspecified narcotics	0.659	0.341
S61 Open wound of wrist and hand	0.659	0.341
Y00-Y09 Assault	0.658	0.342
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.657	0.343
D09 Carcinoma in situ of other and unspecified sites	0.655	0.345
E89.0 Postprocedural hypothyroidism	0.655	0.345
S65 Injury of blood vessels at wrist and hand level	0.655	0.345
S91.3 Open wound of other parts of foot	0.655	0.345
V01-V09 Pedestrian injured in transport accident	0.655	0.345
S42.10 Fracture of scapula (closed)	0.654	0.346
A63.0 Anogenital (venereal) warts	0.654	0.346
E27.2 Addisonian crisis	0.654	0.346
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.653	0.346
E23 Hypofunction and other disorders of pituitary gland	0.653	0.346
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.653	0.347
O34.6 Maternal care for abnormality of vagina	0.653	0.347
O34.5 Maternal care for other abnormalities of gravid uterus	0.653	0.347
O34.3 Maternal care for cervical incompetence	0.653	0.347
O34.0 Maternal care for congenital malformation of uterus	0.653	0.347
O32.4 Maternal care for high head at term	0.653	0.347
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.652	0.348
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.651	0.348
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.651	0.348
T42.5 Mixed antiepileptics, not elsewhere classified	0.651	0.348
T42.3 Barbiturates	0.651	0.348
T42.2 Succinimides and oxazolidinediones	0.651	0.348
T42.0 Hydantoin derivatives	0.651	0.348
W75-W84 Other accidental threats to breathing	0.651	0.348
O34.4 Maternal care for other abnormalities of cervix	0.651	0.349
C69 Malignant neoplasm of eye and adnexa	0.650	0.350
T01 Open wounds involving multiple body regions	0.650	0.350
F10.5 Psychotic disorder	0.650	0.350
D58 Other hereditary haemolytic anaemias	0.650	0.350
E24.8 Other Cushing's syndrome	0.648	0.352
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.648	0.352
E24.3 Ectopic ACTH syndrome	0.648	0.352
E24.1 Nelson's syndrome	0.648	0.352
Q00-Q07 Congenital malformations of the nervous system	0.648	0.352
S67 Crushing injury of wrist and hand	0.648	0.352
S42.4 Fracture of lower end of humerus	0.648	0.352
T13 Other injuries of lower limb, level unspecified	0.647	0.352
T12.X1 Fracture of lower limb, level unspecified (open)	0.647	0.352
T12.X0 Fracture of lower limb, level unspecified (closed)	0.647	0.352
T12 Fracture of lower limb, level unspecified	0.647	0.352
T10.X1 Fracture of upper limb, level unspecified (open)	0.647	0.352
T10.X0 Fracture of upper limb, level unspecified (closed)	0.647	0.352
T10 Fracture of upper limb, level unspecified	0.647	0.352
T08.X1 Fracture of spine, level unspecified (open)	0.647	0.352
T08.X0 Fracture of spine, level unspecified (closed)	0.647	0.352
T08 Fracture of spine, level unspecified	0.647	0.352
D66 Hereditary factor VIII deficiency	0.647	0.353
B35-B49 Mycoses	0.647	0.353
S60 Superficial injury of wrist and hand	0.647	0.353
W22.9 Unspecified place	0.647	0.353
S00-S09 Injuries to the head	0.647	0.353
D03 Melanoma in situ	0.646	0.354
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.645	0.355
Q21 Congenital malformations of cardiac septa	0.645	0.355
D68.5 Primary Thrombophilia	0.645	0.355
F18 Mental and behavioural disorders due to use of volatile solvents	0.645	0.355
F16 Mental and behavioural disorders due to use of hallucinogens	0.645	0.355
F14 Mental and behavioural disorders due to use of cocaine	0.645	0.355
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.645	0.355
F11 Mental and behavioural disorders due to use of opioids	0.645	0.355
E26 Hyperaldosteronism	0.644	0.356
T90.9 Sequelae of unspecified injury of head	0.644	0.356
Chapter IX Diseases of the circulatory system	0.643	0.357
C92.7 Other myeloid leukaemia	0.643	0.357
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.643	0.357
T91 Sequelae of injuries of neck and trunk	0.642	0.358
E74 Other disorders of carbohydrate metabolism	0.642	0.358
C83.7 Burkitt's tumour	0.642	0.358
C83.6 Undifferentiated (diffuse)	0.642	0.358
C83.5 Lymphoblastic (diffuse)	0.642	0.358
C83.4 Immunoblastic (diffuse)	0.642	0.358
C83.2 Mixed small and large cell (diffuse)	0.642	0.358
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.641	0.358
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.641	0.359
S99 Other and unspecified injuries of ankle and foot	0.641	0.359
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.641	0.359
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.640	0.359
O16 Unspecified maternal hypertension	0.640	0.360
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.640	0.360
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.640	0.360
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.640	0.360
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.640	0.360
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.640	0.360
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.640	0.360
T44.1 Other parasympathomimetics [cholinergics]	0.640	0.360
T44.0 Anticholinesterase agents	0.640	0.360
B50-B64 Protozoal diseases	0.639	0.360
X10-X19 Contact with heat and hot substances	0.639	0.361
E27.1 Primary adrenocortical insufficiency	0.639	0.361
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.639	0.361
T00 Superficial injuries involving multiple body regions	0.638	0.362
O20.9 Haemorrhage in early pregnancy, unspecified	0.638	0.362
S42.8 Fracture of other parts of shoulder and upper arm	0.637	0.363
T42.1 Iminostilbenes	0.637	0.363
E15 Nondiabetic hypoglycaemic coma	0.636	0.364
T31.0 Burns involving less than 10% of body surface	0.636	0.364
F52 Sexual dysfunction, not caused by organic disorder or disease	0.636	0.364
F50 Eating disorders	0.636	0.364
T14.1 Open wound of unspecified body region	0.635	0.364
O32.9 Maternal care for malpresentation of foetus, unspecified	0.635	0.365
S96 Injury of muscle and tendon at ankle and foot level	0.634	0.366
F10.8 Other mental and behavioural disorders	0.633	0.366
F10.7 Residual and late-onset psychotic disorder	0.633	0.366
F10.6 Amnesic syndrome	0.633	0.366
S00 Superficial injury of head	0.633	0.367
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.632	0.367
D01 Carcinoma in situ of other and unspecified digestive organs	0.632	0.368
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.632	0.368
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.631	0.369
C51-C58 Malignant neoplasms of female genital organs	0.631	0.369
B90-B94 Sequelae of infectious and parasitic diseases	0.631	0.369
D80-D89 Certain disorders involving the immune mechanism	0.630	0.370
T46.3 Coronary vasodilators, not elsewhere classified	0.630	0.370
C81.9 Hodgkin's disease, unspecified	0.630	0.370
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.630	0.370
E07.8 Other specified disorders of thyroid	0.629	0.370
V40-V49 Car occupant injured in transport accident	0.629	0.371
Q27 Other congenital malformations of peripheral vascular system	0.629	0.371
Q80-Q89 Other congenital malformations	0.628	0.371
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.627	0.373
X20-X29 Contact with venomous animals and plants	0.626	0.373
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.625	0.374
C70 Malignant neoplasm of meninges	0.625	0.374
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.625	0.375
D41.0 Kidney	0.625	0.375
Q26 Congenital malformations of great veins	0.624	0.376
Q25 Congenital malformations of great arteries	0.624	0.376
Q22 Congenital malformations of pulmonary and tricuspid valves	0.624	0.376
Q20 Congenital malformations of cardiac chambers and connexions	0.624	0.376
D68.2 Hereditary deficiency of other clotting factors	0.623	0.376
T92.9 Sequelae of unspecified injury of upper limb	0.623	0.377
V20-V29 Motorcycle rider injured in transport accident	0.623	0.377
S43.1 Dislocation of acromioclavicular joint	0.623	0.377
T51.8 Other alcohols	0.623	0.377
T51.3 Fusel oil	0.623	0.377
T51.2 2-Propanol	0.623	0.377
T51.1 Methanol	0.623	0.377
C76.2 Abdomen	0.622	0.377
S98 Traumatic amputation of ankle and foot	0.622	0.377
S97 Crushing injury of ankle and foot	0.622	0.377
S95 Injury of blood vessels at ankle and foot level	0.622	0.377
S94 Injury of nerves at ankle and foot level	0.622	0.377
C76.3 Pelvis	0.622	0.378
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.622	0.378
O62 Abnormalities of forces of labour	0.621	0.378
F10.9 Unspecified mental and behavioural disorder	0.621	0.379
T59 Toxic effect of other gases, fumes and vapours	0.620	0.379
C91.8 Mature B-cell leukaemia Burkitt-type	0.620	0.380
C91.7 Other lymphoid leukaemia	0.620	0.380
C91.6 Prolymphocytic leukaemia of T-cell type	0.620	0.380
C91.5 Adult T-cell leukaemia	0.620	0.380
C91.3 Prolymphocytic leukaemia	0.620	0.380
C91.2 Subacute lymphocytic leukaemia	0.620	0.380
A65-A69 Other spirochaetal diseases	0.619	0.381
A02 Other Salmonella infections	0.619	0.381
O30.0 Twin pregnancy	0.615	0.385
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.615	0.385
T21.0 Burn of unspecified degree of trunk	0.613	0.387
S29 Other and unspecified injuries of thorax	0.612	0.388
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.611	0.389
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.611	0.389
W21 Striking against or struck by sports equipment	0.611	0.389
Y35-Y36 Legal intervention and operations of war	0.611	0.389
Y10-Y34 Event of undetermined intent	0.611	0.389
X85-X99 Assault	0.611	0.389
X58-X59 Accidental exposure to other and unspecified factors	0.611	0.389
X30-X39 Exposure to forces of nature	0.611	0.389
X00-X09 Exposure to smoke, fire and flames	0.611	0.389
W65-W74 Accidental drowning and submersion	0.611	0.389
V98-V99 Other and unspecified transport accidents	0.611	0.389
V95-V97 Air and space transport accidents	0.611	0.389
V90-V94 Water transport accidents	0.611	0.389
V70-V79 Bus occupant injured in transport accident	0.611	0.389
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.611	0.389
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.611	0.389
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.611	0.389
E29.1 Testicular hypofunction	0.610	0.389
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.609	0.391
Q23.0 Congenital stenosis of aortic valve	0.609	0.391
E03 Other hypothyroidism	0.609	0.391

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations