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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6028466
log Bayes Factor = 4.11798
Chromosome 20   position 38,129,002  (GRCh37) Explore rs6028466 on Ensembl!
Variant rs6028466 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
S80-S89 Injuries to the knee and lower leg
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
S82 Fracture of lower leg, including ankle
0.993 0.007 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.990 0.010 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
E20-E35 Disorders of other endocrine glands
0.987 0.013 0.000
Chapter VII Diseases of the eye and adnexa
0.985 0.015 0.000
C34 Malignant neoplasm of bronchus and lung
0.985 0.015 0.000
M70-M79 Other soft tissue disorders
0.984 0.016 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.983 0.017 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.980 0.020 0.000
S82.8 Fractures of other parts of lower leg
0.976 0.024 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.970 0.030 0.000
C18 Malignant neoplasm of colon
0.970 0.030 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.968 0.032 0.000
C34.9 Bronchus or lung, unspecified
0.967 0.033 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.966 0.034 0.000
C25 Malignant neoplasm of pancreas
0.962 0.038 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.957 0.043 0.000
Chapter XX External causes of morbidity and mortality
0.954 0.046 0.000
M80-M85 Disorders of bone density and structure
0.948 0.052 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.947 0.053 0.000
M79.8 Other specified soft tissue disorders
0.947 0.053 0.000
H40-H42 Glaucoma
0.946 0.054 0.000
C18.7 Sigmoid colon
0.945 0.055 0.000
M79.6 Pain in limb
0.940 0.060 0.000
M77 Other enthesopathies
0.936 0.064 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.932 0.068 0.000
S81 Open wound of lower leg
0.931 0.069 0.000
E10-E14 Diabetes mellitus
0.926 0.074 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.924 0.076 0.000
C71 Malignant neoplasm of brain
0.918 0.082 0.000
H40 Glaucoma
0.918 0.082 0.000
E00-E07 Disorders of thyroid gland
0.914 0.086 0.000
C34.3 Lower lobe, bronchus or lung
0.910 0.090 0.000
M77.1 Lateral epicondylitis
0.906 0.094 0.000
T91 Sequelae of injuries of neck and trunk
0.905 0.095 0.000
X60-X84 Intentional self-harm
0.902 0.098 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.901 0.099 0.000
D68 Other coagulation defects
0.900 0.100 0.000
E23 Hypofunction and other disorders of pituitary gland
0.898 0.102 0.000
C25.9 Pancreas, unspecified
0.894 0.106 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.892 0.108 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.891 0.109 0.000
S82.5 Fracture of medial malleolus
0.888 0.112 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.885 0.115 0.000
S82.2 Fracture of shaft of tibia
0.885 0.115 0.000
H40.0 Glaucoma suspect
0.884 0.116 0.000
C18.9 Colon, unspecified
0.881 0.119 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.881 0.119 0.000
E10 Insulin-dependent diabetes mellitus
0.880 0.120 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.880 0.120 0.000
E24 Cushing's syndrome
0.878 0.122 0.000
E05.9 Thyrotoxicosis, unspecified
0.877 0.123 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.875 0.125 0.000
S86 Injury of muscle and tendon at lower leg level
0.874 0.126 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.871 0.129 0.000
Chapter XXII Codes for special purposes
0.868 0.132 0.000
S60-S69 Injuries to the wrist and hand
0.868 0.132 0.000
C71.9 Brain, unspecified
0.867 0.133 0.000
M80 Osteoporosis with pathological fracture
0.867 0.133 0.000
M79.69 Pain in limb (Site unspecified)
0.866 0.134 0.000
E28 Ovarian dysfunction
0.864 0.136 0.000
H53-H54 Visual disturbances and blindness
0.863 0.137 0.000
T51 Toxic effect of alcohol
0.861 0.139 0.000
M79.62 Pain in limb (Upper arm)
0.856 0.144 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.852 0.148 0.000
E27 Other disorders of adrenal gland
0.849 0.151 0.000
C25.0 Head of pancreas
0.848 0.152 0.000
M79.5 Residual foreign body in soft tissue
0.846 0.154 0.000
S80 Superficial injury of lower leg
0.846 0.154 0.000
S81.8 Open wound of other parts of lower leg
0.842 0.158 0.000
M79.64 Pain in limb (Hand)
0.840 0.160 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.836 0.164 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.833 0.167 0.000
T93 Sequelae of injuries of lower limb
0.832 0.168 0.000
D60-D64 Aplastic and other anaemias
0.829 0.171 0.000
D46 Myelodysplastic syndromes
0.826 0.174 0.000
V80-V89 Other land transport accidents
0.823 0.177 0.000
D68.8 Other specified coagulation defects
0.822 0.178 0.000
T92 Sequelae of injuries of upper limb
0.821 0.179 0.000
C21 Malignant neoplasm of anus and anal canal
0.818 0.182 0.000
T17 Foreign body in respiratory tract
0.818 0.182 0.000
C17 Malignant neoplasm of small intestine
0.817 0.183 0.000
S82.50 Fracture of medial malleolus (closed)
0.813 0.187 0.000
C20 Malignant neoplasm of rectum
0.812 0.188 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.811 0.188 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.811 0.189 0.000
S82.4 Fracture of fibula alone
0.810 0.189 0.000
S82.20 Fracture of shaft of tibia (closed)
0.807 0.193 0.000
C34.2 Middle lobe, bronchus or lung
0.805 0.195 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.805 0.195 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.805 0.195 0.000
H30-H36 Disorders of choroid and retina
0.805 0.195 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.804 0.196 0.000
T40.2 Other opioids
0.802 0.198 0.000
H40.5 Glaucoma secondary to other eye disorders
0.801 0.199 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.800 0.200 0.000
H40.1 Primary open-angle glaucoma
0.798 0.202 0.000
S50-S59 Injuries to the elbow and forearm
0.798 0.202 0.000
M79.7 Fibromyalgia
0.796 0.204 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.796 0.204 0.000
E23.0 Hypopituitarism
0.796 0.204 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.795 0.205 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.795 0.205 0.000
D45 Polycythaemia vera
0.793 0.207 0.000
H43-H45 Disorders of vitreous body and globe
0.791 0.209 0.000
X62.9 Unspecified place
0.789 0.211 0.000
T98 Sequelae of other and unspecified effects of external causes
0.788 0.211 0.000
M91-M94 Chondropathies
0.787 0.213 0.000
M84 Disorders of continuity of bone
0.786 0.214 0.000
C23 Malignant neoplasm of gallbladder
0.785 0.215 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.785 0.215 0.000
E20 Hypoparathyroidism
0.784 0.216 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.777 0.223 0.000
E28.2 Polycystic ovarian syndrome
0.777 0.223 0.000
C18.3 Hepatic flexure
0.776 0.224 0.000
M60-M63 Disorders of muscles
0.773 0.227 0.000
T51.0 Ethanol
0.773 0.227 0.000
S62 Fracture at wrist and hand level
0.772 0.228 0.000
C34.1 Upper lobe, bronchus or lung
0.772 0.228 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.772 0.228 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.769 0.231 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.768 0.232 0.000
D61 Other aplastic anaemias
0.763 0.237 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.763 0.237 0.000
T91.3 Sequelae of injury of spinal cord
0.762 0.238 0.000
H54 Blindness and low vision
0.761 0.239 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.755 0.245 0.000
V10-V19 Pedal cyclist injured in transport accident
0.754 0.245 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.754 0.246 0.000
S82.1 Fracture of upper end of tibia
0.751 0.249 0.000
E29 Testicular dysfunction
0.751 0.249 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.750 0.250 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.750 0.250 0.000
E10.9 Without complications
0.749 0.251 0.000
C18.6 Descending colon
0.749 0.251 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.749 0.251 0.000
S81.0 Open wound of knee
0.748 0.252 0.000
M71 Other bursopathies
0.747 0.253 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.747 0.253 0.000
C69 Malignant neoplasm of eye and adnexa
0.746 0.254 0.000
E24.9 Cushing's syndrome, unspecified
0.746 0.254 0.000
S70-S79 Injuries to the hip and thigh
0.745 0.255 0.000
T19 Foreign body in genito-urinary tract
0.745 0.255 0.000
M79.67 Pain in limb (Ankle and foot)
0.743 0.257 0.000
T91.1 Sequelae of fracture of spine
0.743 0.257 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.743 0.257 0.000
E22 Hyperfunction of pituitary gland
0.742 0.257 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.742 0.258 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.742 0.258 0.000
S80.9 Superficial injury of lower leg, unspecified
0.742 0.258 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.742 0.258 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.741 0.259 0.000
M81 Osteoporosis without pathological fracture
0.741 0.259 0.000
D48.1 Connective and other soft tissue
0.740 0.260 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.739 0.261 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.739 0.261 0.000
E10.3 With ophthalmic complications
0.738 0.262 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.262 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.737 0.263 0.000
C71.1 Frontal lobe
0.737 0.263 0.000
T51.9 Alcohol, unspecified
0.737 0.263 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.737 0.263 0.000
S61 Open wound of wrist and hand
0.734 0.266 0.000
M85 Other disorders of bone density and structure
0.733 0.267 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.732 0.268 0.000
T42.4 Benzodiazepines
0.731 0.268 0.000
E24.0 Pituitary-dependent Cushing's disease
0.731 0.269 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.729 0.271 0.000
M77.0 Medial epicondylitis
0.728 0.272 0.000
D68.0 Von Willebrand's disease
0.726 0.274 0.000
Y57 Other and unspecified drugs and medicaments
0.726 0.274 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.726 0.274 0.000
T58 Toxic effect of carbon monoxide
0.725 0.275 0.000
S81.9 Open wound of lower leg, part unspecified
0.724 0.275 0.000
C45 Mesothelioma
0.724 0.276 0.000
E10.1 With ketoacidosis
0.723 0.277 0.000
T36 Poisoning by systemic antibiotics
0.723 0.277 0.000
E34 Other endocrine disorders
0.722 0.278 0.000
H34 Retinal vascular occlusions
0.721 0.279 0.000
C16 Malignant neoplasm of stomach
0.721 0.279 0.000
V20-V29 Motorcycle rider injured in transport accident
0.720 0.280 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.720 0.280 0.000
H50 Other strabismus
0.718 0.282 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.717 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D61.9 Aplastic anaemia, unspecified
0.717 0.283 0.000
S88 Traumatic amputation of lower leg
0.716 0.283 0.000
S87 Crushing injury of lower leg
0.716 0.283 0.000
S85 Injury of blood vessels at lower leg level
0.716 0.283 0.000
S84 Injury of nerves at lower leg level
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
H46 Optic neuritis
0.715 0.285 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.715 0.285 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.713 0.287 0.000
E10.4 With neurological complications
0.712 0.288 0.000
S82.9 Fracture of lower leg, part unspecified
0.712 0.288 0.000
S82.7 Multiple fractures of lower leg
0.712 0.288 0.000
C25.2 Tail of pancreas
0.712 0.288 0.000
D68.2 Hereditary deficiency of other clotting factors
0.711 0.289 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.710 0.290 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.710 0.290 0.000
C31 Malignant neoplasm of accessory sinuses
0.710 0.290 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.710 0.290 0.000
C37 Malignant neoplasm of thymus
0.710 0.290 0.000
C33 Malignant neoplasm of trachea
0.710 0.290 0.000
D69 Purpura and other haemorrhagic conditions
0.709 0.291 0.000
M86-M90 Other osteopathies
0.708 0.291 0.000
W20-W49 Exposure to inanimate mechanical forces
0.708 0.292 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.707 0.293 0.000
E32 Diseases of thymus
0.707 0.293 0.000
E31 Polyglandular dysfunction
0.707 0.293 0.000
E30 Disorders of puberty, not elsewhere classified
0.707 0.293 0.000
E25 Adrenogenital disorders
0.707 0.293 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.707 0.293 0.000
C34.8 Overlapping lesion of bronchus and lung
0.706 0.294 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.294 0.000
M79.61 Pain in limb (Shoulder region)
0.706 0.294 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.706 0.294 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.705 0.295 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.295 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.705 0.295 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
T56 Toxic effect of metals
0.704 0.296 0.000
H43 Disorders of vitreous body
0.704 0.296 0.000
H20 Iridocyclitis
0.704 0.296 0.000
T93.2 Sequelae of other fractures of lower limb
0.704 0.296 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.703 0.297 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.703 0.297 0.000
M79.9 Soft tissue disorder, unspecified
0.703 0.297 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.703 0.297 0.000
M79.3 Panniculitis, unspecified
0.703 0.297 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.702 0.298 0.000
E13 Other specified diabetes mellitus
0.701 0.299 0.000
Y00-Y09 Assault
0.701 0.299 0.000
S82.86 Maisonneuve's fracture
0.700 0.300 0.000
T17.2 Foreign body in pharynx
0.700 0.300 0.000
W50-W64 Exposure to animate mechanical forces
0.700 0.300 0.000
H15 Disorders of sclera
0.699 0.301 0.000
E23.7 Disorder of pituitary gland, unspecified
0.699 0.301 0.000
E23.2 Diabetes insipidus
0.698 0.302 0.000
D62 Acute posthaemorrhagic anaemia
0.698 0.302 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.698 0.302 0.000
E50-E64 Other nutritional deficiencies
0.697 0.303 0.000
D55-D59 Haemolytic anaemias
0.696 0.304 0.000
C71.0 Cerebrum, except lobes and ventricles
0.696 0.304 0.000
T95 Sequelae of burns, corrosions and frostbite
0.695 0.304 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.695 0.304 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.695 0.304 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.695 0.304 0.000
C18.8 Overlapping lesion of colon
0.695 0.305 0.000
M76 Enthesopathies of lower limb, excluding foot
0.695 0.305 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.692 0.308 0.000
M00-M03 Infectious arthropathies
0.692 0.308 0.000
C71.8 Overlapping lesion of brain
0.692 0.308 0.000
C21.0 Anus, unspecified
0.691 0.309 0.000
D68.6 Other Thrombophilia
0.690 0.310 0.000
C25.8 Overlapping lesion of pancreas
0.689 0.310 0.000
C25.7 Other parts of pancreas
0.689 0.310 0.000
C25.4 Endocrine pancreas
0.689 0.310 0.000
C25.3 Pancreatic duct
0.689 0.310 0.000
C25.1 Body of pancreas
0.689 0.310 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.688 0.312 0.000
H40.8 Other glaucoma
0.688 0.312 0.000
M05-M14 Inflammatory polyarthropathies
0.688 0.312 0.000
D68.5 Primary Thrombophilia
0.688 0.312 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.686 0.314 0.000
C70 Malignant neoplasm of meninges
0.686 0.314 0.000
S80.7 Multiple superficial injuries of lower leg
0.685 0.315 0.000
H54.0 Blindness, both eyes
0.684 0.316 0.000
Y35-Y36 Legal intervention and operations of war
0.684 0.316 0.000
Y10-Y34 Event of undetermined intent
0.684 0.316 0.000
X85-X99 Assault
0.684 0.316 0.000
X50-X57 Overexertion, travel and privation
0.684 0.316 0.000
X30-X39 Exposure to forces of nature
0.684 0.316 0.000
X00-X09 Exposure to smoke, fire and flames
0.684 0.316 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.684 0.316 0.000
W75-W84 Other accidental threats to breathing
0.684 0.316 0.000
W65-W74 Accidental drowning and submersion
0.684 0.316 0.000
V98-V99 Other and unspecified transport accidents
0.684 0.316 0.000
V95-V97 Air and space transport accidents
0.684 0.316 0.000
V90-V94 Water transport accidents
0.684 0.316 0.000
V70-V79 Bus occupant injured in transport accident
0.684 0.316 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.684 0.316 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.684 0.316 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.684 0.316 0.000
V01-V09 Pedestrian injured in transport accident
0.684 0.316 0.000
D66 Hereditary factor VIII deficiency
0.684 0.316 0.000
S10-S19 Injuries to the neck
0.683 0.317 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.683 0.317 0.000
H21 Other disorders of iris and ciliary body
0.682 0.318 0.000
S89 Other and unspecified injuries of lower leg
0.681 0.319 0.000
M82 Osteoporosis in diseases classified elsewhere
0.680 0.320 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.680 0.320 0.000
D43.2 Brain, unspecified
0.680 0.320 0.000
S82.40 Fracture of fibula alone (closed)
0.680 0.320 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.680 0.320 0.000
E04 Other non-toxic goitre
0.680 0.320 0.000
M83 Adult osteomalacia
0.679 0.320 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.679 0.321 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.679 0.321 0.000
M79.88 Other specified soft tissue disorders (Other)
0.679 0.321 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.679 0.321 0.000
S52 Fracture of forearm
0.679 0.321 0.000
M80.8 Other osteoporosis with pathological fracture
0.678 0.321 0.000
H42 Glaucoma in diseases classified elsewhere
0.678 0.322 0.000
C18.1 Appendix
0.678 0.322 0.000
M50-M54 Other dorsopathies
0.677 0.323 0.000
M15-M19 Arthrosis
0.677 0.323 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.676 0.324 0.000
M84.0 Malunion of fracture
0.675 0.325 0.000
D68.9 Coagulation defect, unspecified
0.675 0.325 0.000
M79.68 Pain in limb (Other)
0.674 0.326 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.674 0.326 0.000
E11 Non-insulin-dependent diabetes mellitus
0.674 0.326 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.674 0.326 0.000
M79.1 Myalgia
0.673 0.326 0.000
M79.2 Neuralgia and neuritis, unspecified
0.673 0.327 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.672 0.328 0.000
E26 Hyperaldosteronism
0.672 0.328 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.671 0.329 0.000
M77.5 Other enthesopathy of foot
0.671 0.329 0.000
M77.3 Calcaneal spur
0.671 0.329 0.000
M77.2 Periarthritis of wrist
0.671 0.329 0.000
C17.9 Small intestine, unspecified
0.670 0.330 0.000
H50.1 Divergent concomitant strabismus
0.670 0.330 0.000
H10-H13 Disorders of conjunctiva
0.670 0.330 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.670 0.330 0.000
D67 Hereditary factor IX deficiency
0.668 0.332 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.668 0.332 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.668 0.332 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.668 0.332 0.000
S81.7 Multiple open wounds of lower leg
0.668 0.332 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.666 0.334 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.665 0.335 0.000
M79.79 Fibromyalgia (Site unspecified)
0.664 0.336 0.000
E12 Malnutrition-related diabetes mellitus
0.664 0.336 0.000
T65 Toxic effect of other and unspecified substances
0.663 0.337 0.000
T62 Toxic effect of other noxious substances eaten as food
0.663 0.337 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.663 0.337 0.000
T60 Toxic effect of pesticides
0.663 0.337 0.000
T57 Toxic effect of other inorganic substances
0.663 0.337 0.000
T54 Toxic effect of corrosive substances
0.663 0.337 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.663 0.337 0.000
T52 Toxic effect of organic solvents
0.663 0.337 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.663 0.337 0.000
T55 Toxic effect of soaps and detergents
0.663 0.337 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.661 0.339 0.000
S90-S99 Injuries to the ankle and foot
0.660 0.340 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.660 0.340 0.000
X20-X29 Contact with venomous animals and plants
0.660 0.340 0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level
0.659 0.341 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.659 0.341 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.659 0.341 0.000
Chapter VI Diseases of the nervous system
0.659 0.341 0.000
C71.7 Brain stem
0.658 0.341 0.000
C71.6 Cerebellum
0.658 0.341 0.000
C71.5 Cerebral ventricle
0.658 0.341 0.000
C71.4 Occipital lobe
0.658 0.341 0.000
C71.3 Parietal lobe
0.658 0.341 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.658 0.342 0.000
H40.6 Glaucoma secondary to drugs
0.658 0.342 0.000
H40.4 Glaucoma secondary to eye inflammation
0.658 0.342 0.000
H40.3 Glaucoma secondary to eye trauma
0.658 0.342 0.000
Y44 Agents primarily affecting blood constituents
0.658 0.342 0.000
S71 Open wound of hip and thigh
0.658 0.342 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.657 0.343 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.657 0.343 0.000
M94 Other disorders of cartilage
0.657 0.343 0.000
Y57.9 Drug or medicament, unspecified
0.656 0.344 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.656 0.344 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.655 0.345 0.000
E00 Congenital iodine-deficiency syndrome
0.655 0.345 0.000
U51 Admission status on psychiatric patients
0.655 0.345 0.000
H53 Visual disturbances
0.655 0.345 0.000
M40-M43 Deforming dorsopathies
0.654 0.346 0.000
S56 Injury of muscle and tendon at forearm level
0.653 0.347 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.653 0.347 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.652 0.348 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.651 0.348 0.000
D73 Diseases of spleen
0.651 0.349 0.000
S67 Crushing injury of wrist and hand
0.650 0.350 0.000
M77.19 Lateral epicondylitis (Site unspecified)
0.650 0.350 0.000
M77.18 Lateral epicondylitis-Other
0.650 0.350 0.000
M77.17 Lateral epicondylitis-Ankle/Foot
0.650 0.350 0.000
M77.16 Lateral epicondylitis (Lower leg)
0.650 0.350 0.000
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.650 0.350 0.000
M77.14 Lateral epicondylitis-Hand
0.650 0.350 0.000
M77.13 Lateral epicondylitis-Forearm
0.650 0.350 0.000
M77.11 Lateral epicondylitis-Shldr region
0.650 0.350 0.000
M77.10 Lateral epicondylitis (Multiple sites)
0.650 0.350 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.650 0.350 0.000
C71.2 Temporal lobe
0.649 0.351 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.649 0.351 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.649 0.351 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.649 0.351 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.649 0.351 0.000
H47.2 Optic atrophy
0.649 0.351 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.648 0.352 0.000
C32 Malignant neoplasm of larynx
0.647 0.353 0.000
X84 Intentional self-harm by unspecified means
0.646 0.353 0.000
X83 Intentional self-harm by other specified means
0.646 0.353 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.646 0.353 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.646 0.353 0.000
X80 Intentional self-harm by jumping from a high place
0.646 0.353 0.000
X79 Intentional self-harm by blunt object
0.646 0.353 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.646 0.353 0.000
X76 Intentional self-harm by smoke, fire and flames
0.646 0.353 0.000
X75 Intentional self-harm by explosive material
0.646 0.353 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.646 0.353 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.646 0.353 0.000
X72 Intentional self-harm by handgun discharge
0.646 0.353 0.000
X71 Intentional self-harm by drowning and submersion
0.646 0.353 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.646 0.353 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.646 0.353 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.646 0.353 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.646 0.353 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.646 0.353 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.646 0.353 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.646 0.353 0.000
T15 Foreign body on external eye
0.646 0.354 0.000
T16 Foreign body in ear
0.646 0.354 0.000
S62.3 Fracture of other metacarpal bone
0.646 0.354 0.000
D68.4 Acquired coagulation factor deficiency
0.645 0.354 0.000
D68.1 Hereditary factor XI deficiency
0.645 0.354 0.000
C18.2 Ascending colon
0.645 0.355 0.000
E23.6 Other disorders of pituitary gland
0.644 0.356 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.644 0.356 0.000
E23.1 Drug-induced hypopituitarism
0.644 0.356 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.643 0.356 0.000
T40.4 Other synthetic narcotics
0.643 0.357 0.000
S69 Other and unspecified injuries of wrist and hand
0.642 0.358 0.000
C15 Malignant neoplasm of oesophagus
0.641 0.359 0.000
H35 Other retinal disorders
0.641 0.359 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.640 0.360 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.640 0.360 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.640 0.360 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.640 0.360 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.640 0.360 0.000
T44.0 Anticholinesterase agents
0.640 0.360 0.000
M77.9 Enthesopathy, unspecified
0.640 0.360 0.000
E05.8 Other thyrotoxicosis
0.638 0.361 0.000
E05.5 Thyroid crisis or storm
0.638 0.361 0.000
E05.4 Thyrotoxicosis factitia
0.638 0.361 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.638 0.361 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.638 0.361 0.000
H16 Keratitis
0.639 0.361 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.638 0.362 0.000
D75 Other diseases of blood and blood-forming organs
0.638 0.362 0.000
E20.9 Hypoparathyroidism, unspecified
0.638 0.362 0.000
S82.81 Fractures of other parts of lower leg (open)
0.638 0.362 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.638 0.362 0.000
S80.0 Contusion of knee
0.637 0.362 0.000
S82.51 Fracture of medial malleolus (open)
0.637 0.363 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.636 0.364 0.000
H54.7 Unspecified visual loss
0.636 0.364 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.635 0.365 0.000
E04.2 Non-toxic multinodular goitre
0.635 0.365 0.000
S82.21 Fracture of shaft of tibia (open)
0.634 0.365 0.000
T19.1 Foreign body in bladder
0.633 0.367 0.000
H43.8 Other disorders of vitreous body
0.632 0.368 0.000
E27.9 Disorder of adrenal gland, unspecified
0.632 0.368 0.000
S62.7 Multiple fractures of fingers
0.632 0.368 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.631 0.368 0.000
E10.8 With unspecified complications
0.631 0.369 0.000
E10.7 With multiple complications
0.631 0.369 0.000
E10.6 With other specified complications
0.631 0.369 0.000
E10.0 With coma
0.631 0.369 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.631 0.369 0.000
T40.8 Lysergide [LSD]
0.631 0.369 0.000
T40.7 Cannabis (derivatives)
0.631 0.369 0.000
T40.6 Other and unspecified narcotics
0.631 0.369 0.000
T40.5 Cocaine
0.631 0.369 0.000
T40.3 Methadone
0.631 0.369 0.000
T40.1 Heroin
0.631 0.369 0.000
T40.0 Opium
0.631 0.369 0.000
E10.5 With peripheral circulatory complications
0.631 0.369 0.000
E24.8 Other Cushing's syndrome
0.629 0.370 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.629 0.370 0.000
E24.3 Ectopic ACTH syndrome
0.629 0.370 0.000
E24.2 Drug-induced Cushing's syndrome
0.629 0.370 0.000
E24.1 Nelson's syndrome
0.629 0.370 0.000
X63.0 Home
0.629 0.371 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.628 0.372 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.628 0.372 0.000
S86.0 Injury of Achilles tendon
0.627 0.373 0.000
S86.7 Injury of multiple muscles and tendons at lower leg level
0.627 0.373 0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level
0.627 0.373 0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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