TreeWAS – Variant ID: rs6062302

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C71 Malignant neoplasm of brain	0.644	0.356	0.000
C71.9 Brain, unspecified	0.630	0.370	0.000
C71.2 Temporal lobe	0.629	0.371	0.000
C71.1 Frontal lobe	0.611	0.389	0.000
C71.4 Occipital lobe	0.571	0.429	0.000
C71.0 Cerebrum, except lobes and ventricles	0.561	0.439	0.000
C71.8 Overlapping lesion of brain	0.543	0.457	0.000
C71.3 Parietal lobe	0.517	0.483	0.000
C71.6 Cerebellum	0.473	0.527	0.000
C71.5 Cerebral ventricle	0.455	0.544	0.000
C71.7 Brain stem	0.413	0.586	0.000
G93 Other disorders of brain	0.406	0.594	0.000
G90-G99 Other disorders of the nervous system	0.402	0.598	0.000
G93.3 Postviral fatigue syndrome	0.395	0.605	0.000
G95 Other diseases of spinal cord	0.392	0.608	0.000
G90 Disorders of autonomic nervous system	0.383	0.617	0.000
G93.6 Cerebral oedema	0.378	0.622	0.000
G93.9 Disorder of brain, unspecified	0.372	0.628	0.000
G95.9 Disease of spinal cord, unspecified	0.371	0.629	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.359	0.641	0.000
G90.2 Horner's syndrome	0.351	0.649	0.000
G95.2 Cord compression, unspecified	0.342	0.658	0.000
S00.9 Superficial injury of head, part unspecified	0.333	0.667	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.332	0.668	0.000
G93.0 Cerebral cysts	0.328	0.672	0.000
G93.5 Compression of brain	0.327	0.673	0.000
G95.8 Other specified diseases of spinal cord	0.326	0.674	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.314	0.686	0.000
G93.2 Benign intracranial hypertension	0.313	0.687	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.302	0.698	0.000
G95.1 Vascular myelopathies	0.298	0.702	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.295	0.705	0.000
G93.7 Reye's syndrome	0.291	0.709	0.000
S00 Superficial injury of head	0.291	0.709	0.000
G92 Toxic encephalopathy	0.279	0.721	0.000
S00.1 Contusion of eyelid and periocular area	0.279	0.721	0.000
G90.4 Autonomic dysreflexia	0.274	0.725	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.274	0.725	0.000
G90.8 Other disorders of autonomic nervous system	0.272	0.727	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.267	0.733	0.000
S00.0 Superficial injury of scalp	0.261	0.739	0.000
G90.3 Multisystem degeneration	0.259	0.741	0.000
G96 Other disorders of central nervous system	0.252	0.747	0.000
G91 Hydrocephalus	0.244	0.756	0.000
G93.8 Other specified disorders of brain	0.243	0.757	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.243	0.757	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.242	0.757	0.000
G94.1 Hydrocephalus in neoplastic disease	0.240	0.760	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.235	0.765	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.234	0.766	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.225	0.775	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.225	0.775	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.216	0.783	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.216	0.783	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.216	0.784	0.000
G95.0 Syringomyelia and syringobulbia	0.214	0.786	0.000
S00.4 Superficial injury of ear	0.214	0.786	0.000
G91.0 Communicating hydrocephalus	0.209	0.791	0.000
H04.2 Epiphora	0.204	0.796	0.000
G93.4 Encephalopathy, unspecified	0.202	0.797	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.202	0.798	0.000
G96.9 Disorder of central nervous system, unspecified	0.200	0.800	0.000
S00.3 Superficial injury of nose	0.199	0.801	0.000
H04 Disorders of lachrymal system	0.194	0.806	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.192	0.808	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.192	0.808	0.000
S00.5 Superficial injury of lip and oral cavity	0.190	0.810	0.000
C61 Malignant neoplasm of prostate	0.185	0.815	0.000
G96.0 Cerebrospinal fluid leak	0.185	0.815	0.000
H04.1 Other disorders of lachrymal gland	0.182	0.818	0.000
G96.8 Other specified disorders of central nervous system	0.178	0.821	0.000
G91.9 Hydrocephalus, unspecified	0.175	0.825	0.000
H04.8 Other disorders of lachrymal system	0.174	0.826	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.174	0.826	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.172	0.827	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.169	0.831	0.000
G97.8 Other postprocedural disorders of nervous system	0.166	0.833	0.000
S00-S09 Injuries to the head	0.164	0.836	0.000
G91.2 Normal-pressure hydrocephalus	0.163	0.837	0.000
C70 Malignant neoplasm of meninges	0.162	0.838	0.000
H04.4 Chronic inflammation of lachrymal passages	0.162	0.838	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.162	0.838	0.000
T39.1 4-Aminophenol derivatives	0.162	0.838	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.160	0.840	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.160	0.840	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.159	0.841	0.000
K51.9 Ulcerative colitis, unspecified	0.154	0.846	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.154	0.846	0.000
T40.2 Other opioids	0.154	0.846	0.000
C69 Malignant neoplasm of eye and adnexa	0.150	0.850	0.000
H04.9 Disorder of lachrymal system, unspecified	0.148	0.852	0.000
H04.0 Dacryoadenitis	0.148	0.852	0.000
S02 Fracture of skull and facial bones	0.147	0.853	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.146	0.854	0.000
E11.3 With ophthalmic complications	0.144	0.856	0.000
E11 Non-insulin-dependent diabetes mellitus	0.143	0.857	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.142	0.858	0.000
G91.1 Obstructive hydrocephalus	0.138	0.862	0.000
T40.6 Other and unspecified narcotics	0.137	0.862	0.000
H04.6 Other changes in lachrymal passages	0.137	0.863	0.000
S00.7 Multiple superficial injuries of head	0.136	0.864	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.136	0.864	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.135	0.865	0.000
E10-E14 Diabetes mellitus	0.134	0.866	0.000
G91.8 Other hydrocephalus	0.133	0.867	0.000
E11.9 Without complications	0.133	0.867	0.000
T36 Poisoning by systemic antibiotics	0.133	0.867	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.131	0.869	0.000
C72.0 Spinal cord	0.130	0.870	0.000
E10 Insulin-dependent diabetes mellitus	0.130	0.870	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.130	0.870	0.000
T17 Foreign body in respiratory tract	0.128	0.872	0.000
S05 Injury of eye and orbit	0.128	0.872	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.127	0.873	0.000
S02.2 Fracture of nasal bones	0.127	0.873	0.000
S60-S69 Injuries to the wrist and hand	0.127	0.873	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.126	0.874	0.000
E10.5 With peripheral circulatory complications	0.126	0.874	0.000
T92 Sequelae of injuries of upper limb	0.126	0.874	0.000
T45.0 Antiallergic and antiemetic drugs	0.125	0.874	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.125	0.875	0.000
C72.9 Central nervous system, unspecified	0.125	0.875	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.125	0.875	0.000
C72.5 Other and unspecified cranial nerves	0.125	0.875	0.000
C72.4 Acoustic nerve	0.125	0.875	0.000
C72.3 Optic nerve	0.125	0.875	0.000
C72.2 Olfactory nerve	0.125	0.875	0.000
C72.1 Cauda equina	0.125	0.875	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.125	0.875	0.000
T40.3 Methadone	0.124	0.875	0.000
T40.1 Heroin	0.124	0.876	0.000
E11.0 With coma	0.124	0.876	0.000
S02.5 Fracture of tooth	0.123	0.877	0.000
S08 Traumatic amputation of part of head	0.123	0.877	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.123	0.877	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.122	0.878	0.000
T92.1 Sequelae of fracture of arm	0.122	0.878	0.000
T23 Burn and corrosion of wrist and hand	0.121	0.879	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.120	0.880	0.000
K51 Ulcerative colitis	0.120	0.880	0.000
S64 Injury of nerves at wrist and hand level	0.119	0.881	0.000
E11.8 With unspecified complications	0.119	0.881	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.119	0.881	0.000
S02.6 Fracture of mandible	0.118	0.881	0.000
E10.1 With ketoacidosis	0.118	0.882	0.000
S07 Crushing injury of head	0.117	0.882	0.000
S04 Injury of cranial nerves	0.117	0.882	0.000
S62 Fracture at wrist and hand level	0.117	0.883	0.000
C69.6 Orbit	0.117	0.883	0.000
S02.8 Fractures of other skull and facial bones	0.117	0.883	0.000
E10.0 With coma	0.117	0.883	0.000
C70.9 Meninges, unspecified	0.116	0.883	0.000
C70.1 Spinal meninges	0.116	0.883	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.116	0.884	0.000
T40.4 Other synthetic narcotics	0.116	0.884	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.115	0.884	0.000
E11.6 With other specified complications	0.115	0.885	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.115	0.885	0.000
T40.8 Lysergide [LSD]	0.115	0.885	0.000
T40.7 Cannabis (derivatives)	0.115	0.885	0.000
T40.0 Opium	0.115	0.885	0.000
T39.4 Antirheumatics, not elsewhere classified	0.115	0.885	0.000
T39.2 Pyrazolone derivatives	0.115	0.885	0.000
T42.4 Benzodiazepines	0.114	0.886	0.000
E11.4 With neurological complications	0.114	0.886	0.000
S02.20 Fracture of nasal bones (closed)	0.114	0.886	0.000
S62.3 Fracture of other metacarpal bone	0.114	0.886	0.000
E10.4 With neurological complications	0.114	0.886	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.114	0.886	0.000
T45.2 Vitamins, not elsewhere classified	0.113	0.887	0.000
E13 Other specified diabetes mellitus	0.112	0.888	0.000
S02.3 Fracture of orbital floor	0.112	0.888	0.000
T45.5 Anticoagulants	0.112	0.888	0.000
T17.2 Foreign body in pharynx	0.111	0.889	0.000
T36.3 Macrolides	0.111	0.889	0.000
T25 Burn and corrosion of ankle and foot	0.111	0.889	0.000
T93 Sequelae of injuries of lower limb	0.111	0.889	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.111	0.889	0.000
C70.0 Cerebral meninges	0.110	0.889	0.000
C69.0 Conjunctiva	0.110	0.890	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.110	0.890	0.000
S02.0 Fracture of vault of skull	0.110	0.890	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.108	0.892	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.108	0.892	0.000
C69.2 Retina	0.107	0.892	0.000
C69.8 Overlapping lesion of eye and adnexa	0.107	0.892	0.000
C69.5 Lachrymal gland and duct	0.107	0.892	0.000
C69.1 Cornea	0.107	0.892	0.000
T45.4 Iron and its compounds	0.107	0.892	0.000
T40.5 Cocaine	0.107	0.893	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.107	0.893	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.107	0.893	0.000
S02.50 Fracture of tooth (closed)	0.106	0.894	0.000
S90-S99 Injuries to the ankle and foot	0.106	0.894	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.106	0.894	0.001
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.106	0.894	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.106	0.894	0.000
S64.3 Injury of digital nerve of thumb	0.106	0.894	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.105	0.895	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.105	0.895	0.000
T23.2 Burn of second degree of wrist and hand	0.105	0.895	0.000
T23.3 Burn of third degree of wrist and hand	0.105	0.895	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.105	0.895	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.104	0.895	0.000
T45.8 Other primarily systemic and haematological agents	0.104	0.895	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.104	0.895	0.000
T45.6 Fibrinolysis-affecting drugs	0.104	0.895	0.000
T45.3 Enzymes, not elsewhere classified	0.104	0.895	0.000
S10-S19 Injuries to the neck	0.104	0.896	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.104	0.896	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.104	0.896	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.103	0.897	0.000
T36.0 Penicillins	0.103	0.897	0.000
T20 Burn and corrosion of head and neck	0.103	0.897	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.102	0.898	0.000
T17.5 Foreign body in bronchus	0.102	0.898	0.000
T33-T35 Frostbite	0.102	0.898	0.000
T42.0 Hydantoin derivatives	0.102	0.898	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.102	0.898	0.000
T21 Burn and corrosion of trunk	0.102	0.898	0.000
E14 Unspecified diabetes mellitus	0.102	0.898	0.000
C69.4 Ciliary body	0.101	0.898	0.000
S62.2 Fracture of first metacarpal bone	0.101	0.899	0.000
S05.8 Other injuries of eye and orbit	0.101	0.899	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.101	0.899	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.100	0.900	0.000
T51 Toxic effect of alcohol	0.100	0.900	0.000
T39.0 Salicylates	0.100	0.900	0.000
E11.7 With multiple complications	0.099	0.900	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.099	0.901	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.098	0.901	0.000
K51.5 Mucosal proctocolitis	0.098	0.902	0.000
T42.3 Barbiturates	0.098	0.902	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.098	0.902	0.000
E11.2 With renal complications	0.098	0.902	0.000
S02.60 Fracture of mandible (closed)	0.098	0.902	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.098	0.902	0.000
S03.2 Dislocation of tooth	0.097	0.902	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.097	0.902	0.000
T42.2 Succinimides and oxazolidinediones	0.097	0.902	0.000
C69.9 Eye, unspecified	0.097	0.903	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.097	0.903	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.097	0.903	0.000
S02.1 Fracture of base of skull	0.097	0.903	0.000
E13.9 Without complications	0.097	0.903	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.096	0.903	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.096	0.904	0.000
E12 Malnutrition-related diabetes mellitus	0.096	0.904	0.000
T42.1 Iminostilbenes	0.095	0.905	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.095	0.905	0.000
T36.9 Systemic antibiotic, unspecified	0.095	0.905	0.000
T36.8 Other systemic antibiotics	0.095	0.905	0.000
T36.7 Antifungal antibiotics, systemically used	0.095	0.905	0.000
T36.6 Rifamycins	0.095	0.905	0.000
T36.5 Aminoglycosides	0.095	0.905	0.000
T36.2 Chloramphenicol group	0.095	0.905	0.000
S03.1 Dislocation of septal cartilage of nose	0.095	0.905	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.095	0.905	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.095	0.905	0.000
S02.4 Fracture of malar and maxillary bones	0.095	0.905	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.095	0.905	0.000
E10.6 With other specified complications	0.095	0.905	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.095	0.905	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.095	0.905	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.095	0.905	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.094	0.906	0.000
S08.1 Traumatic amputation of ear	0.094	0.906	0.000
S64.1 Injury of median nerve at wrist and hand level	0.094	0.906	0.000
E10.8 With unspecified complications	0.094	0.906	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.094	0.906	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.094	0.906	0.000
T17.3 Foreign body in larynx	0.093	0.906	0.000
T63 Toxic effect of contact with venomous animals	0.093	0.907	0.000
S02.7 Multiple fractures involving skull and facial bones	0.093	0.907	0.000
S05.1 Contusion of eyeball and orbital tissues	0.093	0.907	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.092	0.908	0.000
S67 Crushing injury of wrist and hand	0.092	0.908	0.000
T17.4 Foreign body in trachea	0.092	0.908	0.000
T17.1 Foreign body in nostril	0.092	0.908	0.000
T17.0 Foreign body in nasal sinus	0.092	0.908	0.000
S05.7 Avulsion of eye	0.092	0.908	0.000
T25.2 Burn of second degree of ankle and foot	0.091	0.908	0.000
S03.0 Dislocation of jaw	0.091	0.908	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.091	0.909	0.000
S03.4 Sprain and strain of jaw	0.091	0.909	0.000
S03.3 Dislocation of other and unspecified parts of head	0.091	0.909	0.000
S63.5 Sprain and strain of wrist	0.091	0.909	0.000
T15 Foreign body on external eye	0.091	0.909	0.000
T51.0 Ethanol	0.091	0.909	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.091	0.909	0.000
T98 Sequelae of other and unspecified effects of external causes	0.091	0.909	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.090	0.909	0.000
K51.2 Ulcerative (chronic) proctitis	0.091	0.909	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.090	0.910	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.090	0.910	0.000
T49.9 Topical agent, unspecified	0.090	0.910	0.000
T49.8 Other topical agents	0.090	0.910	0.000
T49.7 Dental drugs, topically applied	0.090	0.910	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.090	0.910	0.000
T49.5 Ophthalmological drugs and preparations	0.090	0.910	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.090	0.910	0.000
T49.3 Emollients, demulcents and protectants	0.090	0.910	0.000
T49.2 Local astringents and local detergents	0.090	0.910	0.000
T49.1 Antipruritics	0.090	0.910	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.090	0.910	0.000
C69.3 Choroid	0.090	0.910	0.000
E10.7 With multiple complications	0.089	0.910	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.089	0.910	0.000
S65 Injury of blood vessels at wrist and hand level	0.089	0.910	0.000
T91 Sequelae of injuries of neck and trunk	0.089	0.911	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.089	0.911	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.089	0.911	0.000
S02.51 Fracture of tooth (open)	0.089	0.911	0.000
S08.9 Traumatic amputation of unspecified part of head	0.088	0.911	0.000
S08.8 Traumatic amputation of other parts of head	0.088	0.911	0.000
S08.0 Avulsion of scalp	0.088	0.911	0.000
T00-T07 Injuries involving multiple body regions	0.088	0.912	0.000
T47.6 Antidiarrhoeal drugs	0.088	0.912	0.000
S63.1 Dislocation finger	0.088	0.912	0.000
T92.0 Sequelae of open wound of upper limb	0.088	0.912	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.088	0.912	0.000
S62.7 Multiple fractures of fingers	0.088	0.912	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.087	0.912	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.087	0.912	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.087	0.912	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.087	0.912	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.087	0.912	0.000
T44.0 Anticholinesterase agents	0.087	0.912	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.087	0.913	0.000
E10.2 With renal complications	0.087	0.913	0.000
T23.7 Corrosion of third degree of wrist and hand	0.087	0.913	0.000
T23.6 Corrosion of second degree of wrist and hand	0.087	0.913	0.000
T23.5 Corrosion of first degree of wrist and hand	0.087	0.913	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.087	0.913	0.000
S02.30 Fracture of orbital floor (closed)	0.087	0.913	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.087	0.913	0.000
T54 Toxic effect of corrosive substances	0.087	0.913	0.000
E14.5 With peripheral circulatory complications	0.086	0.914	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.086	0.914	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.086	0.914	0.000
T47.7 Emetics	0.086	0.914	0.000
T47.5 Digestants	0.086	0.914	0.000
T47.3 Saline and osmotic laxatives	0.086	0.914	0.000
T56 Toxic effect of metals	0.086	0.914	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.086	0.914	0.000
T55 Toxic effect of soaps and detergents	0.086	0.914	0.000
S14 Injury of nerves and spinal cord at neck level	0.086	0.914	0.000
S02.01 Fracture of vault of skull (open)	0.086	0.914	0.000
T62 Toxic effect of other noxious substances eaten as food	0.086	0.914	0.000
T95 Sequelae of burns, corrosions and frostbite	0.086	0.914	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.085	0.914	0.000
S64.8 Injury of other nerves at wrist and hand level	0.085	0.914	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.085	0.915	0.000
S02.61 Fracture of mandible (open)	0.085	0.915	0.000
T20.2 Burn of second degree of head and neck	0.085	0.915	0.000
S02.21 Fracture of nasal bones (open)	0.085	0.915	0.000
S04.9 Injury of unspecified cranial nerve	0.084	0.915	0.000
S04.8 Injury of other cranial nerves	0.084	0.915	0.000
S04.7 Injury of accessory nerve	0.084	0.915	0.000
S04.6 Injury of acoustic nerve	0.084	0.915	0.000
S04.5 Injury of facial nerve	0.084	0.915	0.000
S04.4 Injury of abducent nerve	0.084	0.915	0.000
S04.3 Injury of trigeminal nerve	0.084	0.915	0.000
S04.2 Injury of trochlear nerve	0.084	0.915	0.000
S04.1 Injury of oculomotor nerve	0.084	0.915	0.000
S04.0 Injury of optic nerve and pathways	0.084	0.915	0.000
S07.9 Crushing injury of head, part unspecified	0.084	0.915	0.000
S07.8 Crushing injury of other parts of head	0.084	0.915	0.000
S07.1 Crushing injury of skull	0.084	0.915	0.000
S07.0 Crushing injury of face	0.084	0.915	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.084	0.916	0.000
T18 Foreign body in alimentary tract	0.084	0.916	0.000
T36.4 Tetracyclines	0.084	0.916	0.000
T50.1 Loop [high-ceiling] diuretics	0.084	0.916	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.084	0.916	0.000
S02.81 Fractures of other skull and facial bones (open)	0.084	0.916	0.000
S62.4 Multiple fractures of metacarpal bones	0.084	0.916	0.000
T60 Toxic effect of pesticides	0.084	0.916	0.000
T57 Toxic effect of other inorganic substances	0.084	0.916	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.084	0.916	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.084	0.916	0.000
T16 Foreign body in ear	0.083	0.916	0.000
T29 Burns and corrosions of multiple body regions	0.083	0.917	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.083	0.917	0.000
S63.2 Multiple dislocations of fingers	0.083	0.917	0.000
S62.1 Fracture of other carpal bone(s)	0.083	0.917	0.000
T41.5 Therapeutic gases	0.083	0.917	0.000
T41.4 Anaesthetic, unspecified	0.083	0.917	0.000
T41.3 Local anaesthetics	0.083	0.917	0.000
T41.1 Intravenous anaesthetics	0.083	0.917	0.000
T41.0 Inhaled anaesthetics	0.083	0.917	0.000
T21.3 Burn of third degree of trunk	0.083	0.917	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.083	0.917	0.000
T52 Toxic effect of organic solvents	0.083	0.917	0.000
T47.0 Histamine H(2)-receptor antagonists	0.082	0.917	0.000
E13.3 With ophthalmic complications	0.082	0.917	0.000
T41.2 Other and unspecified general anaesthetics	0.082	0.918	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.082	0.918	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.082	0.918	0.000
T21.2 Burn of second degree of trunk	0.082	0.918	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.082	0.918	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.082	0.918	0.000
S10 Superficial injury of neck	0.081	0.918	0.000
T50.4 Drugs affecting uric acid metabolism	0.081	0.919	0.000
S98 Traumatic amputation of ankle and foot	0.081	0.919	0.000
T93.0 Sequelae of open wound of lower limb	0.081	0.919	0.000
S70-S79 Injuries to the hip and thigh	0.081	0.919	0.000
S99 Other and unspecified injuries of ankle and foot	0.081	0.919	0.000
T47.4 Other laxatives	0.081	0.919	0.000
E13.8 With unspecified complications	0.081	0.919	0.000
E13.7 With multiple complications	0.081	0.919	0.000
E13.6 With other specified complications	0.081	0.919	0.000
E13.5 With peripheral circulatory complications	0.081	0.919	0.000
E13.4 With neurological complications	0.081	0.919	0.000
E13.2 With renal complications	0.081	0.919	0.000
E13.1 With ketoacidosis	0.081	0.919	0.000
E13.0 With coma	0.081	0.919	0.000
S93.1 Dislocation of toe(s)	0.081	0.919	0.000
S02.31 Fracture of orbital floor (open)	0.080	0.919	0.000
S12 Fracture of neck	0.081	0.919	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.080	0.920	0.000
E14.3 With ophthalmic complications	0.080	0.920	0.000
E14.2 Withrenal complications	0.080	0.920	0.000
T20.0 Burn of unspecified degree of head and neck	0.080	0.920	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.080	0.920	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.080	0.920	0.000
T25.7 Corrosion of third degree of ankle and foot	0.080	0.920	0.000
T25.6 Corrosion of second degree of ankle and foot	0.080	0.920	0.000
T25.5 Corrosion of first degree of ankle and foot	0.080	0.920	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.080	0.920	0.000
T25.1 Burn of first degree of ankle and foot	0.080	0.920	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.080	0.920	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.080	0.920	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.079	0.921	0.000
T48.4 Expectorants	0.079	0.921	0.000
T48.3 Antitussives	0.079	0.921	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.079	0.921	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.079	0.921	0.000
T48.0 Oxytocic drugs	0.079	0.921	0.000
C60-C63 Malignant neoplasms of male genital organs	0.079	0.921	0.000
S62.5 Fracture of thumb	0.078	0.922	0.000
T94.1 Sequelae of injuries, not specified by body region	0.078	0.922	0.000
T31 Burns classified according to extent of body surface involved	0.078	0.922	0.000
E14.6 With other specified complications	0.078	0.922	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.078	0.922	0.000
T47.2 Stimulant laxatives	0.078	0.922	0.000
T50.7 Analeptics and opioid receptor antagonists	0.078	0.922	0.000
T50.5 Appetite depressants	0.078	0.922	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.078	0.922	0.000
T50.0 Mineralocorticoids and their antagonists	0.078	0.922	0.000
T25.3 Burn of third degree of ankle and foot	0.077	0.922	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.077	0.923	0.000
T59 Toxic effect of other gases, fumes and vapours	0.077	0.923	0.000
S05.9 Injury of eye and orbit, part unspecified	0.077	0.923	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.077	0.923	0.000
S90 Superficial injury of ankle and foot	0.077	0.923	0.000
T79-T79 Certain early complications of trauma	0.077	0.923	0.000
S63.6 Sprain and strain of finger(s)	0.077	0.923	0.000
K51.4 Pseudopolyposis of colon	0.077	0.923	0.000
S95 Injury of blood vessels at ankle and foot level	0.076	0.924	0.000
S94 Injury of nerves at ankle and foot level	0.076	0.924	0.000
S02.00 Fracture of vault of skull (closed)	0.076	0.924	0.000
S62.31 Fracture of other metacarpal bone (open)	0.076	0.924	0.000
T30 Burn and corrosion, body region unspecified	0.076	0.924	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.076	0.924	0.000
T26 Burn and corrosion confined to eye and adnexa	0.076	0.924	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.076	0.924	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.076	0.924	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.076	0.924	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.076	0.924	0.000
S17 Crushing injury of neck	0.075	0.925	0.000
S15 Injury of blood vessels at neck level	0.075	0.925	0.000
S18 Traumatic amputation at neck level	0.075	0.925	0.000
S16 Injury of muscle and tendon at neck level	0.075	0.925	0.000
T23.1 Burn of first degree of wrist and hand	0.075	0.925	0.000
T91.3 Sequelae of injury of spinal cord	0.075	0.925	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.075	0.925	0.000
T28 Burn and corrosion of other internal organs	0.074	0.925	0.000
T27 Burn and corrosion of respiratory tract	0.074	0.925	0.000
T20.7 Corrosion of third degree of head and neck	0.074	0.926	0.000
T20.6 Corrosion of second degree of head and neck	0.074	0.926	0.000
T20.5 Corrosion of first degree of head and neck	0.074	0.926	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.074	0.926	0.000
D50.9 Iron deficiency anaemia, unspecified	0.074	0.926	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.073	0.926	0.000
T34 Frostbite with tissue necrosis	0.073	0.926	0.000
T33 Superficial frostbite	0.073	0.926	0.000
T21.1 Burn of first degree of trunk	0.073	0.926	0.000
T21.7 Corrosion of third degree of trunk	0.073	0.926	0.000
T21.6 Corrosion of second degree of trunk	0.073	0.926	0.000
T21.5 Corrosion of first degree of trunk	0.073	0.926	0.000
T21.4 Corrosion of unspecified degree of trunk	0.073	0.926	0.000
S02.11 Fracture of base of skull (open)	0.073	0.927	0.000
K50-K52 Noninfective enteritis and colitis	0.073	0.927	0.000
E14.7 With multiple complications	0.073	0.927	0.000
S62.21 Fracture of first metacarpal bone (open)	0.073	0.927	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.073	0.927	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.072	0.927	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.072	0.927	0.000
T37.5 Antiviral drugs	0.072	0.927	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations